CN218128779U

CN218128779U - Solid tumor tracer

Info

Publication number: CN218128779U
Application number: CN202123113785.8U
Authority: CN
Inventors: 周星; 苏文宇; 徐华苹; 罗丽飞; 张武
Original assignee: Guangzhou T K Medical Instrument Co ltd
Current assignee: Guangzhou T K Medical Instrument Co ltd
Priority date: 2021-12-10
Filing date: 2021-12-10
Publication date: 2022-12-27
Anticipated expiration: 2031-12-10

Abstract

The utility model discloses a solid tumor tracing device, which comprises a displacement prevention mechanism, a delivery mechanism, a developing mechanism and a medical optical tracing system; the medical optical tracing system carries out optical tracing on the anti-shifting mechanism. The medical optical tracing system comprises a light source and an optical tracing carrier. Light emitted by the light source is conducted through the optical tracing carrier, and then the optical tracing carrier is optically traced. The light source can also adopt a miniature LED light source, and the light-emitting end of the LED light source and the optical tracing carrier are directly arranged into a whole to be placed in a human body for optical tracing. Because the design has medical optics tracer system, the utility model discloses a solid tumour tracer can carry out the spike of solid tumour through visible light after getting into human, during the operation, the switch-on light source, optics tracer carrier trace preventing shifting mechanism, just can be under the guide of light, and the position at solid tumour place is observed directly perceivedly to the naked eye, and clinical operation is safer, convenient.

Description

Solid tumor tracer

Technical Field

The utility model relates to a medical tracer system, especially a solid tumour tracer.

Background

With the great improvement of the resolution of the medical imaging equipment, some tumor tissues can be found in a very small volume, such as lung nodules, uterine fibroids, esophageal tumors, liver tumors and the like. Because these tumor tissues are small in size, such as lung nodules, and are difficult to accurately identify during the endoscopic resection, the tumor tissues to be resected need to be identified, and the surgical resection is convenient under the endoscope.

At present, the calibration of small-volume tumor tissues is usually to place an identification mechanism such as a positioning hook in an X-ray environment, then to retain the identification mechanism such as the positioning hook at the tumor tissues, and to perform an operation by identifying the position of the identification mechanism in the operation process.

Because of the marking mechanism usually is very small in size, and just develop easily under the environment such as X-ray, consequently, under the chamber mirror, during the operation process, because the interference effect of blood etc. marking mechanism often hardly discerns to cause the position of the difficult accurate judgement tumour of operation process.

The utility model discloses a tumour tissue based on visible light technique, especially solid tumour's demarcation technique and device.

Disclosure of Invention

The utility model aims to solve the problem that the position can't accurately be differentiateed to small size tumor tissue or solid tumor tissue in current clinical operation, through the setting that adopts the optics spike mode, in clinical operation, through the setting of different colour light sources, the tumor tissue that needs the excision among the clinical operation is differentiateed to the accuracy, conveniently carries out the operation excision of tumor tissue under the chamber mirror.

The utility model discloses a solid tumour tracer, its characterized in that: the solid tumor tracing device 910 comprises a medical optical tracing system 500; the medical optical tracing system 500 is placed in a solid tumor, and the solid tumor is identified by a visible light tracing technology.

The medical optical tracing system 500 can emit visible light under the action of the optical tracing carrier 2, and can rapidly and effectively identify solid tumors and perform surgical excision by the prompt of the visible light in clinical operations.

The solid tumor tracking device 910 contains a visualization mechanism 4. The development mechanism 4 can perform development prompt in the scenes such as X-ray, magnetic navigation, B-ultrasonic and the like, so that the solid tumor tracer 910 can be conveniently placed.

The solid tumor tracking device 910 includes an anti-migration mechanism 910-1. The anti-displacement mechanism 910-1 can be fixed on the solid tumor to be calibrated to prevent the solid tumor tracing apparatus 910 from displacing along with the human body movement, such as the lung breathing movement, the intestinal tract movement, the stomach movement, etc.

The solid tumor tracking device 910 includes a delivery mechanism 910-2. The delivery mechanism 910-2 can deliver the anti-migration mechanism 910-1 to a solid tumor to be identified.

In clinical application, the delivery mechanism 910-2 delivers the anti-displacement mechanism 910-1 to the position of the solid tumor under X-ray or MRI and fixes the anti-displacement mechanism 910-1 on the solid tumor, and the optical tracing carrier 2 is disposed on the anti-displacement mechanism 910-1 to position the anti-displacement mechanism 910-1, so that the position of the solid tumor can be visually observed under the guidance of light during operation.

The anti-shift mechanism 910-1 is configured to have a hook-shaped structure, a horn-shaped structure, a dumbbell-shaped structure, a spiral spring-shaped structure, and/or a nail-shaped structure when in an operating state. The applicant herein only illustrates the manner of the above-mentioned several structures of the anti-displacement mechanism 910-1, and in practical applications, those skilled in the art can design the anti-displacement mechanism 910-1 with different structures as required, and the applicant does not exemplify here, but does not depart from the scope of the present application.

The anti-displacement mechanism 910-1 is of a hook-shaped structure and at least comprises 1 positioning hook 910-11.

The anti-shifting mechanism 910-1 includes 2 positioning hooks 910-11. Generally, the displacement prevention mechanism 910-1 comprises 2 or 3 positioning hooks 910-11 to better prevent the displacement prevention mechanism 910-1 from displacing along with the movement of the human body, such as the respiratory movement of the lung, the peristalsis of the intestinal tract, etc.

The anti-displacement mechanism 910-1 is made of shape memory alloy, is in a linear structure when in vitro, and is restored to a set hook-shaped structure, and/or a horn-shaped structure, and/or a dumbbell-shaped structure, and/or a spiral spring-shaped structure, and/or a nail-shaped structure under the action of body temperature after entering a human body.

The anti-displacement mechanism 910-1 is made of a developing material, and the developing mechanism 4 is configured to perform development under X-ray, MRI, and/or B-ultrasound. In clinical use, the anti-migration mechanism 910-1 is placed into the tumor tissue to be targeted under X-ray, MRI and/or B-ultrasound.

The delivery mechanism 910-2 includes a pushing mechanism 910-21 and a delivery sheath 910-22.

The anti-migration mechanism 910-1 is disposed within the delivery sheath 910-22, and the pushing mechanism 910-21 is capable of pushing the anti-migration mechanism 910-1 out of the delivery sheath 910-22 and into a solid tumor.

The pushing mechanism 910-22 may be fixedly connected to the displacement prevention mechanism 910-1, and the displacement prevention mechanism 910-1 is pushed out from the delivery sheath 910-21 and stays together in the body; the pushing mechanism 910-22 can also be detachably connected to the anti-migration mechanism 910-1, and after the anti-migration mechanism 910-1 is pushed out from the delivery sheath 910-21, the anti-migration mechanism 910-1 is disconnected, so that the anti-migration mechanism 910-1 can be left at the solid tumor only.

The medical optical tracing system 500 comprises a light source 1 and an optical tracing carrier 2;

A. the optical tracing carrier 2 contains light guide material;

B. the light emitted by the light source 1 is conducted through the optical tracing carrier 2, and the optical tracing carrier 2 is optically traced.

The optical tracing carrier 2 can optically trace the shifting mechanism 910-1.

The light source 1 is an LED light source 11, and/or a medical cold light source 12, and/or natural light. The light source 1 can be various light sources capable of emitting light, and the light emitted by the light source 1 can be traced after being transmitted by the optical tracing carrier 1. Compared with a common lighting light source, the LED light source 11 has the characteristics of small volume, high luminous efficiency, strong light source directivity and the like, and particularly has the advantage that the common light source cannot compare with the LED light source in the aspect of safety. Firstly, the LED light source is supplied with low-voltage direct current, and the supply voltage is only 6 to 24V; secondly, mercury is not added in the LED light source, so that poisoning and other injuries to a human body cannot be caused; in addition, more importantly, the LED light source is a cold light source, can not generate heat seriously in the working process, can be safely touched, and can not cause accidental high-temperature scald to human bodies. The medical cold light source 12 is a common light source used in the existing operation process, and the light source 1 can be arranged at the back, is easy to obtain in an operating room, and does not need additional equipment.

The color of the light emitted by the light source 1 can be set according to the background color or the penetration requirement. Through the setting of light, in clinical operation, the doctor can directly see through the tissue through the naked eye the position at 2 places of optical tracer carriers, and then in the accurate clinical operation of differentiateing, blood vessel, tissue or the organ that need key protection effectively avoid the unexpected injury of operation in-process. The light emitted by the light source 1 can be arranged differently according to the background color in the body cavity or the tissue to be penetrated, when the tissue is required to be penetrated, the red color and the yellow color are better, and the purple color and the white color are second order.

The light source 1 is a blinking type light emission. The light source 1 may be set to be intermittently lighted, flickered, etc. as required.

The intensity of the light emitted by the light source 1 can be set. The intensity of the light emitted by the light source 1 can also be adjusted as required to adapt to different clinical environments. The illumination intensity of the light emitted by the light source 1 can reach 30 ten thousand lux, and the preferred range is 5 thousand lux to 15 ten thousand lux.

The light source 1 comprises a control system 13, the control system 13 comprises a wavelength adjusting mechanism 13-1 and a light intensity adjusting mechanism 13-2, the wavelength adjusting mechanism 13-1 can adjust the color of the emitted light through adjusting the wavelength, and the light intensity adjusting mechanism 13-2 can adjust the illumination of the emitted light.

The LED light source 11 is disposed inside the body, and/or outside the body. Because the volume of the light emitting end 11-1 of the LED light source 11 can be very small, the LED light source 11 can be arranged outside the human body, and the optical tracing carrier 2 can conduct light rays to the human body and can be directly arranged in the human body, and the optical tracing carrier 2 is coated outside and is directly arranged at the position needing tracing.

The optical tracing carrier 2 is a light-storing self-luminous tracing carrier 21. Self-luminous material is a material capable of absorbing energy in some way and converting it into unbalanced light radiation, and the process of converting the energy absorbed inside the material into unbalanced light radiation is the luminescence process. Especially, the light-storing self-luminous material can continuously emit light for more than 12 hours in a dark environment after a few minutes or tens of minutes under the action of external light, and can meet the tracing requirements of most operation time. The light-storing and self-luminous tracing carrier 21 can directly absorb the energy of lamplight in an operating room, so that various external lights can form the light source 1 without being directly connected with the light source 1, and the use process is very simple.

The light-storing and self-luminous tracing carrier 21 contains a light-storing and self-luminous body 21-1 and a protective carrier 21-2.

The protective carrier 21-2 is made of transparent light guide material, and the light storage self-luminous body 21-1 is arranged in the protective carrier 21-2 in a sealing mode.

The light-storing self-luminous body 21-1 can absorb external energy and perform conversion luminescence. The protective carrier 21-2 is made of transparent medical materials and can be directly contacted with tissues, and the light energy emitted by the light-storing and self-luminous body 21-1 through energy conversion can effectively penetrate for effective tracing, and meanwhile, the biological safety of clinical use is guaranteed. The light-storing self-luminous body 21-1 can be arranged at different positions and designed into different shapes, and fixed-point tracing or integral tracing can be carried out according to requirements.

The optical trace carrier 2 is a light-conducting optical fiber 22. The light guide fiber 22 has a good light guide effect, can conduct light to different positions according to needs, can be switched on or switched off according to needs, and is very convenient for clinical use.

The light-guiding optical fiber 22 has a non-smooth surface 22-1.

The non-smooth surface 22-1 is a non-smooth surface 22-11 that is capable of forming reflections, and/or scattering. The non-smooth surface 22-1 can realize the overall luminescence of the non-smooth surface 22-1 through the reflection and/or scattering of light, so as to achieve the overall tracing effect.

The light guide fiber 22 is provided with a light outlet 22-2 intermittently. Each light outlet 22-2 which is arranged intermittently is provided with a light transmitting surface 22-21 and a reflecting surface 22-22, light is transmitted through the light transmitting surface 22-21, when reaching the reflecting surface 22-22, the light is reflected and emitted from the light outlet 22-2 to form a tracing point, and a plurality of light outlets 22-2 can form a chain-shaped tracing band.

The light guide optical fibers 22 are woven into a net shape, and light outlets 22-2 are distributed at different positions in a scattered manner. The light guide fibers 22 are woven into a mesh shape, the lengths of the light guide fibers 22 can be set to be different, the light outlets 22-2 of the light guide fibers 22 are also different, and the light outlets are scattered and distributed, so that the integral tracing of a three-dimensional space can be realized, and because the light outlet 22-1 is not required to be arranged in the middle of each light guide fiber 22, the light conduction effect is better, and the visual effect of a single tracing point is very bright. The light exit 22-2 may be disposed on a side surface, and the light guide fiber 22 capable of being lit integrally may be woven into a mesh shape, so as to realize full-area tracing of the entire displacement prevention mechanism 910-1.

The surface of the light guide optical fiber 22 contains a coating 3. The coating 3 can be designed with coatings of different properties, such as an anti-coagulant coating, a hydrophilic coating or a hydrophobic coating, as desired.

The optical tracing carrier 2 is provided with a developing mechanism 4, and the developing mechanism 4 carries out development under X-ray, MRI and/or B-ultrasonic. The developing mechanism 4 may be a developing line, and/or a developing ring, and/or a developing block, and the like. The applicant only exemplifies the above several development modes, and in practical applications, a person skilled in the art can design different development modes according to needs. The developing mechanism 4 can carry out development prompt under the scenes of X-ray, magnetic navigation or B-ultrasonic and the like, and the developing mechanism 4 is convenient for the optical tracing carrier 2 can be placed into tumor tissues under the condition of visibility or navigation.

The optical tracing carrier 2 is made of a compliant medical material and is arranged on the outer surface of the displacement prevention mechanism 910-1.

The optical tracing carrier 2 is a light guide optical fiber 22, a proximal end of the light guide optical fiber 22 is connected with a light guide joint 26, a distal end of the light guide optical fiber 22 is connected and fixed to the displacement prevention mechanism 910-1, and a light outlet 22-2 of the light guide optical fiber 22 is arranged on the displacement prevention mechanism 910-1 to trace the displacement prevention mechanism 910-1.

The light guide fiber 22 has a non-smooth surface 22-1, a light outlet 22-2 is formed in the side surface of the light guide fiber 22, and the light guide fiber 22 integrally traces the displacement prevention mechanism 910-1.

The light guide optical fiber 22 is made of a flexible medical material and is fixedly connected to the displacement prevention mechanism 910-1, and when the displacement prevention mechanism 910-1 deforms, the light guide optical fiber 22 deforms along with the displacement prevention mechanism 910-1. Since the light guide fiber 22 can be integrally lighted, the light guide fiber 22 can be wound around the displacement prevention mechanism 910-1, especially the positioning hook 910-11, and deformed together with the displacement prevention mechanism 910-1, especially when the displacement prevention mechanism 910-1 is made of shape memory alloy, the shape of the light guide fiber 22 is changed along with the change of the shape of the displacement prevention mechanism 910-1, so as to ensure the tracing effect on the displacement prevention mechanism 910-1.

The light source 1 of the medical optical tracing system 500 is an LED light source 11, the optical tracing carrier 2 is made of a transparent material, the light emitting end 11-1 of the LED light source 11 is disposed on the optical tracing carrier 2, and is disposed on the displacement prevention mechanism 910-1 or the displacement prevention mechanism 910-1 together with the optical tracing carrier 2, so as to trace the displacement prevention mechanism 910-1.

When the light source 1 adopts the LED light source 11, the light emitting end 11-1 of the LED light source 11 can be packaged with the optical tracing carrier 2 into a whole, and is disposed at the position of the displacement prevention mechanism 910-1 to be traced, and the light emitted from the light emitting end 11-1 is transmitted by the light guide material of the optical tracing carrier 2 and then displayed, so as to identify the position of the solid tumor in clinic.

The LED light source 11 comprises a light emitting end 11-1, a circuit system 11-2, a driving board 11-3 and a power supply 11-4; the light-emitting end 11-1 is connected with the driving board 11-3 and the power supply 11-4 through the circuit system 11-2, under the control of the driving board 11-3, the power supply 11-4 supplies power to the light-emitting end 11-1 through the circuit system 11-2, and the light-emitting end 11-1 emits light; the driving board 11-3 and the power supply 11-4 are arranged outside the body, and the light emitting end 11-1 is arranged inside the body to trace the displacement prevention mechanism 910-1.

The circuit system 11-2 is a flexible circuit board 11-21, and the light emitting ends 11-1 of the LED light sources 11 are dispersedly disposed on the flexible circuit board 11-21 and encapsulated in the optical tracing carrier 2 to form an LED light strip, an LED light net, or an LED light ball, which is disposed on the displacement prevention mechanism 910-1 to trace the displacement prevention mechanism 910-1.

The LED light source 11 may be packaged by using a single light emitting end 11-1 for fixed-point tracing. The circuit system 11-2 may also be a flexible circuit board 11-21, and the light-emitting end 11-1 is dispersedly disposed at any position of the flexible circuit board 11-21, so as to form a light-emitting strip, and the light-emitting strip is wound on the anti-displacement mechanism 910-1, or a plurality of LED light sources 11 are packaged together with the optical tracing carrier 2 into a net shape, a sphere shape, or the like, so as to trace the anti-displacement mechanism 910-1 as a whole.

The light emitting end 11-1 of the LED light source 11 is disposed on the displacement prevention mechanism 910-1, the optical tracing carrier 2 made of a transparent material is coated outside the light emitting end 11-1, and the light emitted by the light emitting end 11-1 traces the displacement prevention mechanism 910-1.

The light emitting end 11-1 is dispersedly arranged on the anti-displacement mechanism 910-1, and the anti-displacement mechanism (910-1) is integrally traced.

The light emitting end 11-1 can be directly disposed on the displacement prevention mechanism 910-1, and then the optical tracing carrier 2 made of transparent material is coated outside, so that the light emitting end 11-1 can completely fit the outer contour of the displacement prevention mechanism 910-1, and traces any shape of the displacement prevention mechanism 910-1.

In addition, the light emitting end 11-1 is symmetrically arranged, the optical tracing carrier 2 is externally coated, the anti-displacement mechanism 910-1 can be formed by utilizing the internal support of the light emitting end 11-1 and the circuit system 11-2 and the volume of the light emitting end 11-1, and the medical optical tracing system 500 can have both tracing function and positioning function of the anti-displacement mechanism 910-1.

The circuit system 11-2 is a flexible circuit board 11-21, the optical tracing carrier 2 is made of a soft transparent material, the light emitting end 11-1, the flexible circuit board 11-21 and the developing mechanism 4 are arranged in the optical tracing carrier 2 and arranged on the displacement prevention mechanism 910-1, and when the displacement prevention mechanism 910-1 deforms, the light emitting end 11-1, the flexible circuit board 11-21, the developing mechanism 4 and the optical tracing carrier 2 deform together with the displacement prevention mechanism 910-1. Especially, when the anti-displacement mechanism 910-1 is made of shape memory alloy, the shape of the flexible circuit board 11-21 changes along with the change of the shape of the anti-displacement mechanism 910-1, so as to ensure the tracing effect on the anti-displacement mechanism 910-1.

In clinical use, the anti-displacement mechanism 910-1 is disposed in the delivery sheath 910-21, the delivery sheath 910-21 is inserted into a position where a solid tumor is located under X-ray or MRI conditions, the anti-displacement mechanism 910-1 is pushed out by the pushing mechanism 910-22 and fixed on the solid tumor, the delivery sheath 910-21 is removed, the anti-displacement mechanism 910-1 is stopped and fixed on the solid tumor, and the light source 1 is switched on during surgery, and the optical tracing carrier traces the anti-displacement mechanism 910-1, so that the position where the solid tumor is located can be visually observed under the guidance of light.

The utility model discloses a solid tumor tracing device, which comprises a displacement prevention mechanism 910-1, a delivery mechanism 910-2, a developing mechanism 4 and a medical optical tracing system 500; the medical optical tracing system 500 optically traces the displacement prevention mechanism 910-1. The medical optical tracing system 500 includes a light source 1 and an optical tracing carrier 2. And after the light emitted by the light source 1 is transmitted by the optical tracing carrier 2, the optical tracing carrier 2 is optically traced. The light source 1 can also adopt the miniature LED light source 11, and the light emitting end 11-1 of the LED light source 11 and the optical tracing carrier 2 are directly arranged into a whole to be placed in a human body for optical tracing. Because the design has medical optics tracer system 500, the utility model discloses a solid tumour tracer can carry out the spike of solid tumour through visible light after getting into human, during the operation, the switch-on light source 1, optics tracer carrier 2 is right prevent that aversion mechanism 910-1 carries out the tracer, just can be under the guide of light, the position at solid tumour place is observed directly perceivedly to the naked eye, and clinical operation is safer, convenient.

Drawings

Fig. 1 is a schematic perspective view of a solid tumor tracer device according to the present invention, which is hooked in a delivery sheath.

Fig. 1-1 isbase:Sub>A sectional viewbase:Sub>A-base:Sub>A of fig. 1.

Fig. 1-2 are enlarged views at A1 of fig. 1.

Fig. 2 is a schematic view of the positioning hook of fig. 1 in a structure when pushed out.

Fig. 2-1 is a sectional view B-B of fig. 2.

Fig. 2-2 is an enlarged view at B1 of fig. 2.

Fig. 2-3 is an enlarged view at B2 of fig. 2-2.

Fig. 2-4 are exploded views of fig. 2.

Fig. 3 is a schematic structural view of the light emitting end of the LED light source arranged on the positioning hook.

Fig. 3-1 is an enlarged view at C1 of fig. 3.

Fig. 4 is a schematic structural diagram of a solid tumor tracer device of the present invention comprising an interrupted open casing.

Fig. 4-1 is an enlarged view at D1 of fig. 4.

Fig. 5 is a schematic diagram of a structure containing a plurality of solid tumor tracking devices.

Fig. 5-1 is an exploded view of fig. 5.

Fig. 6 is a schematic structural diagram of a solid tumor tracer device of the present invention comprising a spherical anti-displacement mechanism.

Fig. 6-1 is a cross-sectional view E-E of fig. 6.

Fig. 6-2 is an enlarged view at E1 of fig. 6-1.

Fig. 7 is a schematic structural diagram of a solid tumor tracing device of the present invention comprising a dumbbell-shaped anti-displacement mechanism.

Fig. 7-1 is an enlarged view at F1 of fig. 7.

Fig. 7-2 is a sectional view F-F of fig. 7.

Fig. 7-3 is an enlarged view at F2 of fig. 7-2.

Fig. 7-4 are dumbbell-type anti-shifting mechanisms with coatings.

Fig. 8 is a schematic structural view of the solid tumor tracer device of the invention comprising a screw type displacement prevention mechanism.

Fig. 8-1 is an enlarged view of G1 of fig. 8.

Fig. 9 is a schematic structural diagram of a solid tumor tracing device of the present invention including both a spiral constant and dumbbell type anti-displacement mechanism.

Fig. 9-1 is an enlarged view at H1 of fig. 9.

Fig. 10 is a schematic structural diagram of a solid tumor tracing device of the present invention including an LED light source.

Fig. 10-1 is a schematic view of the delivery mechanism of fig. 10 after removal.

Fig. 11 is a schematic structural diagram of a tracing device for solid tumor of the present invention including a medical cold light source.

Fig. 12 is a schematic structural diagram of a solid tumor tracing device of the present invention containing light-storing self-luminous tracing carriers.

Fig. 12-1 is an enlarged view at I1 of fig. 12.

Fig. 13 is a schematic diagram of the operation of the solid tumor tracer of the invention when inserted into a lung nodule.

Fig. 13-1 is a schematic diagram of the operation of fig. 13 with the light source connected to the light guide fiber of the delivery mechanism removed.

In the above figures:

500 is a medical optical tracing system, 910 is the solid tumor tracing apparatus of the present invention.

1 is a light source, 2 is an optical tracing carrier, 3 is a coating, 4 is a developing mechanism, and 5 is a protective sleeve.

11 is an LED light source, 12 is a medical cold light source, 13 is a control system, 11-1 is a light emitting end, 11-2 is a circuit system, 11-3 is a driving plate, 11-4 is a power supply, 13-1 is a wavelength adjusting mechanism, 13-2 is a light intensity adjusting mechanism, and 11-21 is a flexible circuit board.

21 is a light-storing self-luminous tracing carrier, 22 is a light guide optical fiber, and 26 is a light guide joint; 21-1 is a light-storing self-luminous body, and 21-2 is a protective carrier; 22-1 is a non-smooth surface, and 22-2 is a light outlet; 22-11 is a non-smooth surface capable of forming reflection and/or scattering, 22-21 is a conduction surface, and 22-22 is a reflection surface.

910-1 is an anti-shifting mechanism, 910-2 is a delivery mechanism; 910-11 is a positioning hook, 910-21 is a delivery sheath, and 910-22 is a pushing mechanism.

Detailed Description

Example 1: the utility model discloses a solid tumor tracer

Referring to fig. 1 to 5-1, the present embodiment includes an anti-displacement mechanism 910-1, a delivery mechanism 910-2, a visualization mechanism 4, and a medical optical tracing system 500, wherein the medical optical tracing system 500 optically traces the anti-displacement mechanism 910-1.

The anti-displacement mechanism 910-1 can be fixed on the solid tumor to be calibrated to prevent the solid tumor tracing apparatus 910 from displacing along with the human body movement, such as the lung breathing movement, the intestinal tract movement, the stomach movement, etc.

The color of the light emitted by the light source 1 can be set according to the background color or the penetration requirement. Through the setting of light, in clinical operation, the doctor can directly see through the tissue through the naked eye the position at 2 places of optical tracer carriers, and then in the accurate clinical operation of differentiateing, blood vessel, tissue or the organ that need key protection effectively avoid the unexpected injury of operation in-process. The light emitted by the light source 1 can be arranged differently according to the background color in the body cavity or the tissue to be penetrated, when the tissue is required to be penetrated, the red color and the yellow color are better, and the purple color and the white color are inferior.

The light source 1 is a flicker type light emitting. The light source 1 may be set to be intermittently lighted, flickering, etc. as required.

Referring to fig. 10 and 11, the light source 1 includes a control system 13, the control system 13 includes a wavelength adjusting mechanism 13-1 and a light intensity adjusting mechanism 13-2, the wavelength adjusting mechanism 13-1 can adjust the color of the emitted light by adjusting the wavelength, and the light intensity adjusting mechanism 13-2 can adjust the illuminance of the emitted light.

Referring to fig. 1 to 5-1, in the present embodiment, the anti-shift mechanism 910-1 is in a hook-shaped structure in an operating state, and includes 2 positioning hooks 910-11.

Generally, the displacement prevention mechanism 910-1 comprises 2 or 3 positioning hooks 910-11 to better prevent the displacement of the displacement prevention mechanism 910-1 along with the movement of the human body, such as the respiratory movement of the lung, the peristalsis of the intestinal tract, and the like.

In practical applications, the anti-shift mechanism 910-1 may also be a ball-shaped structure (refer to fig. 6 to 6-2), a trumpet-shaped structure, and/or a dumbbell-shaped structure (refer to fig. 7 to 7-3, fig. 9 and 9-1), and/or a coil spring-shaped structure (refer to fig. 8 and 8-1, fig. 9 and 9-1), and/or a nail-shaped structure in the operating state. The applicant herein only illustrates the manner of the above-mentioned several structures of the anti-displacement mechanism 910-1, and in practical applications, those skilled in the art can design the anti-displacement mechanism 910-1 with different structures as required, and the applicant does not exemplify here, but does not depart from the scope of the present application.

The anti-displacement mechanism 910-1 may be made of shape memory alloy, and has a linear structure when in vitro, and after entering into the human body, it will return to a set hook-shaped structure, and/or a horn-shaped structure, and/or a dumbbell-shaped structure, and/or a coil spring-shaped structure, and/or a nail-shaped structure under the action of body temperature.

In this embodiment, the anti-displacement mechanism 910-1 is made of a developing material, and the developing mechanism 4 is configured to perform development under X-ray, MRI, and/or B-ultrasound. In clinical use, the anti-migration mechanism 910-1 is placed into the tumor tissue to be targeted under X-ray, MRI and/or B-ultrasonic.

Referring to fig. 1 and 1-1, the anti-migration mechanism 910-1 is disposed within the delivery sheath 910-22, and the pushing mechanism 910-21 is capable of pushing the anti-migration mechanism 910-1 out of the delivery sheath 910-22 and into a solid tumor.

The pushing mechanism 910-22 can be fixedly connected to the anti-displacement mechanism 910-1, and the anti-displacement mechanism 910-1 can be pushed out from the delivery sheath 910-21 and stays together in the body; the pushing mechanism 910-22 can also be detachably connected to the anti-migration mechanism 910-1, and after the anti-migration mechanism 910-1 is pushed out from the delivery sheath 910-21, the anti-migration mechanism 910-1 is disconnected, so that the anti-migration mechanism 910-1 can be left at the solid tumor only.

The medical optical tracing system 500 comprises a light source 1 and an optical tracing carrier 2.

The optical tracing carrier 2 contains a light guide material, and light emitted by the light source 1 is conducted through the optical tracing carrier 2 and carries out optical tracing on the optical tracing carrier 2.

The optical tracing carrier 2 can optically trace the displacement mechanism 910-1.

Referring to fig. 10 to 11, the light source 1 may be an LED light source 11, and/or a medical cold light source 12, and/or natural light. The light source 1 can be various light sources capable of emitting light, and the light emitted by the light source 1 can be traced after being transmitted by the optical tracing carrier 1. Compared with a common lighting light source, the LED light source 11 has the characteristics of small volume, high luminous efficiency, strong light source directivity and the like, and particularly has the advantage that the common light source cannot compare with the LED light source in the aspect of safety. Firstly, the LED light source is supplied with low-voltage direct current, and the supply voltage is only 6 to 24V; secondly, mercury is not added in the LED light source, so that poisoning and other injuries to a human body cannot be caused; in addition, the LED light source is a cold light source, so that the LED light source does not generate heat seriously in the working process, can be safely touched and does not cause accidental high-temperature scalding to a human body. The medical cold light source 12 is a common light source used in the existing operation process, and the light source 1 can be arranged at the back, is easy to obtain in an operating room, and does not need additional equipment.

In this embodiment, the light source 1 is the LED light source 11.

The LED light source 11 may be disposed inside the body or outside the body. Because the volume of the light emitting end 11-1 of the LED light source 11 can be very small, the size of the light emitting end 11-1 is usually controlled below 2mm, for example, an LED lamp with a package size of 0.2 mm-0.5 mm, the LED light source 11 can be not only arranged outside the body and conducts light into the human body through the optical tracing carrier 2, but also can be directly arranged in the human body, and the optical tracing carrier 2 is externally coated and directly arranged at a part needing tracing.

When the LED light source 11 is arranged outside the body, the optical tracing carrier 2 is a light guiding fiber 22. The light guide optical fiber 22 has a good light guide effect, conducts light to different positions according to needs, can be switched on or switched off according to needs, and is very convenient for clinical use.

Referring to fig. 2 and 4, in the present embodiment, the light guide fiber 22 has a non-smooth surface 22-1.

The non-smooth surface 22-1 is a non-smooth surface 22-11 that is capable of forming reflections, and/or scatters. The overall luminescence of the non-smooth surface 22-1 can be achieved, achieving an overall tracing effect.

The light guide fiber 22 is provided with a light outlet 22-2 intermittently. Each light outlet 22-2 which is arranged intermittently is provided with a light transmitting surface 22-21 and a reflecting surface 22-22, light is transmitted through the light transmitting surface 22-21, when reaching the reflecting surface 22-22, the light is reflected and emitted from the light outlet 22-2 to form a tracing point, and a plurality of light outlets 22-2 can form a chain-shaped tracing band. The light guide fiber 22 may be fixed to the displacement prevention mechanism 910-1 by a protection sleeve 5, as shown in the drawing.

The light guide fiber 22 can also be woven into a net shape, and light outlets 22-2 are distributed at different positions in a scattered manner. The light guide fibers 22 are woven into a mesh shape, the lengths of the light guide fibers 22 can be set to be different, the light outlets 22-2 of the light guide fibers 22 are also different, and the light outlets are scattered and distributed, so that the integral tracing of a three-dimensional space can be realized, and because the light outlet 22-1 is not required to be arranged in the middle of each light guide fiber 22, the light conduction effect is better, and the visual effect of a single tracing point is very bright. The light exit 22-2 may be disposed on a side surface of the light guide fiber 22, and the light guide fiber 22 capable of being lit integrally may be woven into a mesh shape, so as to realize the full-area tracing of the entire displacement prevention mechanism 910-1.

Referring to fig. 7-4, the surface of the light-guiding fiber 22 may be provided with a coating 3. The coating 3 can be designed with different properties as desired, such as an anti-coagulant coating, a hydrophilic coating or a hydrophobic coating.

When the anti-displacement mechanism 910-1 is made of a non-imaging material, the imaging mechanism 4 may be disposed on the optical tracing carrier 2, and the imaging mechanism 4 performs imaging under X-ray, MRI, and/or B-ultrasonic. The developing mechanism 4 may be a developing line 41, and/or a developing ring 42, and/or a developing block 43, and the like. The applicant herein only illustrates the above several development modes, and in practical applications, those skilled in the art may design different development modes according to needs. The developing mechanism 4 can perform developing prompt in scenes such as X-ray, magnetic navigation or B-ultrasonic, and the developing mechanism 4 is convenient for the optical tracing carrier 2 to be placed into tumor tissue under the condition of visualization or navigation, and the reference figure is a drawing.

In this embodiment, the proximal end of the light guide fiber 22 is connected to the light guide connector 26, the distal end of the light guide fiber 22 is connected to and fixed to the displacement prevention mechanism 910-1, and the light outlet 22-2 of the light guide fiber 22 is disposed on the displacement prevention mechanism 910-1.

Referring to fig. 2 to 2-3, the light guide fiber 22 is made of a flexible medical material and is connected and fixed to the displacement prevention mechanism 910-1, and when the displacement prevention mechanism 910-1 deforms, the light guide fiber 22 deforms along with the displacement prevention mechanism 910-1. Since the light guide fiber 22 can be integrally lighted, the light guide fiber 22 can be wound around the displacement prevention mechanism 910-1, especially the positioning hook 910-11, and deformed together with the displacement prevention mechanism 910-1, especially when the displacement prevention mechanism 910-1 is made of shape memory alloy, the shape of the light guide fiber 22 is changed along with the change of the shape of the displacement prevention mechanism 910-1, so as to ensure the tracing effect on the displacement prevention mechanism 910-1.

When the LED light source 11 is designed in a micro-scale, the LED light source 11 comprises a light-emitting end 11-1 and a circuit system 11-2. The light emitting end 11-1 may be disposed in the body.

At this time, the optical tracing carrier 2 is made of a transparent material, and the light emitting end 11-1 of the LED light source 11 can be packaged on the optical tracing carrier 2, and is disposed on the displacement preventing mechanism 910-1 together with the optical tracing carrier 2 to trace the displacement preventing mechanism 910-1.

The light emitted by the light-emitting end 11-1 is transmitted by the light guide material of the optical tracing carrier 2 and then displayed for clinical identification of the position of the solid tumor.

Referring to fig. 3 and 3-1 and fig. 7 to 7-3, the LED light source 11 includes a light emitting terminal 11-1, a circuit system 11-2, a driving board 11-3 and a power supply 11-4; the light-emitting end 11-1 is connected with the driving board 11-3 and the power supply 11-4 through the circuit system 11-2, under the control of the driving board 11-3, the power supply 11-4 supplies power to the light-emitting end 11-1 through the circuit system 11-2, and the light-emitting end 11-1 emits light; the driving board 11-3 and the power supply 11-4 are arranged outside the body, and the light emitting end 11-1 is arranged inside the body to trace the displacement prevention mechanism 910-1.

The LED light sources 11 may be packaged by using a single light emitting end 11-1 for fixed-point tracing, or the circuit system 11-2 may be a flexible circuit board 11-21, and the light emitting ends 11-1 are dispersedly disposed at any position of the flexible circuit board 11-21, so as to form a light emitting band, and the light emitting band is wound around the displacement prevention mechanism 910-1, or the plurality of LED light sources 11 and the optical tracing carrier 2 are packaged together into a mesh shape, a spherical shape, or the like, so as to integrally trace the displacement prevention mechanism 910-1.

The light emitting end 11-1 of the LED light source 11 may also be directly disposed on the anti-shift mechanism 910-1, the optical tracing carrier 2 made of a transparent material is coated outside the anti-shift mechanism, and light emitted from the light emitting end 11-1 traces the anti-shift mechanism 910-1.

The light emitting end 11-1 can be directly disposed on the displacement prevention mechanism 910-1 and then externally coated with the optical tracing carrier 2 made of transparent material, so that the light emitting end 11-1 can completely conform to the external contour of the displacement prevention mechanism 910-1 to trace the shape of the displacement prevention mechanism 910-1 in any shape.

In addition, the light emitting end 11-1 is symmetrically disposed, the optical tracing carrier 2 is externally wrapped, the anti-displacement mechanism 910-1 can be formed by using the internal support of the light emitting end 11-1 and the circuit system 11-2 and the self volume of the light emitting end 11-1, and the medical optical tracing system 500 can have both tracing function and positioning function of the anti-displacement mechanism 910-1, refer to fig. 7-4.

The circuit system 11-2 is a flexible circuit board 11-21, the optical tracing carrier 2 is made of a soft transparent material, the light emitting end 11-1, the flexible circuit board 11-21 and the developing mechanism 4 are arranged in the optical tracing carrier 2 and arranged on the displacement prevention mechanism 910-1, and when the displacement prevention mechanism 910-1 deforms, the light emitting end 11-1, the flexible circuit board 11-21, the developing mechanism 4 and the optical tracing carrier 2 deform together with the displacement prevention mechanism 910-1. Particularly, when the anti-displacement mechanism 910-1 is made of shape memory alloy, as the shape of the anti-displacement mechanism 910-1 changes, the shape of the flexible circuit board 11-21 changes, so as to ensure the tracing effect on the anti-displacement mechanism 910-1.

With reference to fig. 12 and 12-1, the optical trace carrier 2 is a light-accumulating self-luminescent trace carrier 21. Self-luminous material is a material capable of absorbing energy in some way and converting it into unbalanced light radiation, and the process of converting the energy absorbed inside the material into unbalanced light radiation is the luminescence process. Especially, the light-storing self-luminous material can continuously emit light for more than 12 hours in a dark environment after a few minutes or tens of minutes under the action of external light, and can meet the tracing requirements of most operation time. The light-storing and self-luminous tracing carrier 21 can directly absorb the energy of lamplight in an operating room, so that various external lights can form the light source 1 without being directly connected with the light source 1, and the use process is very simple.

Referring to fig. 13, in clinical application, when a lung tumor (especially a lung nodule) or a liver tumor needs to be marked, the anti-displacement mechanism 910-1 is disposed in the delivery sheath 910-21, the delivery sheath 910-21 is inserted into a position of a solid tumor under X-ray, the anti-displacement mechanism 910-1 is pushed out by the pushing mechanism 910-22 and fixed on the solid tumor such as the lung tumor (especially the lung nodule) or the liver tumor, then the delivery sheath 910-21 is removed, the anti-displacement mechanism 910-1 is stopped and fixed on the solid tumor, and the light-guiding optical fiber 22 is connected to the light source 1, referring to fig. 13-1, the light source 1 is switched on during surgery, and the optical tracing carrier 2 traces the anti-displacement mechanism 910-1, so that the position of the lung tumor (especially the lung nodule) or the liver tumor can be visually observed under the guidance of light.

In clinical application, if hysteromyoma needs to be calibrated, the anti-displacement mechanism 910-1 can be delivered to the hysteromyoma under the guidance of B-ultrasonic waves and fixed on the hysteromyoma, the light source 1 is switched on during operation, and the optical tracing carrier 2 traces the anti-displacement mechanism 910-1, so that the position of the hysteromyoma can be visually observed by naked eyes under the guidance of light.

The solid tumour tracer of this embodiment is owing to the design medical optics tracer system 500, the utility model discloses a solid tumour tracer can carry out the spike of solid tumour through visible light after getting into human body, during the operation, the switch-on light source 1, optics tracer carrier is right prevent that aversion mechanism 910-1 carries out the spike, just can be under the guide of light, and the position at solid tumour place is observed directly perceivedly to the naked eye, and clinical operation is safer, convenient.

It should be noted that structures disclosed and described herein may be replaced by other structures having the same effect, and the described embodiments of the invention are not the only structures for carrying out the invention. Although preferred embodiments of the present invention have been shown and described herein, it will be understood by those skilled in the art that these embodiments are by way of example only, and that numerous changes, modifications and substitutions may be made without departing from the scope of the invention as defined in the appended claims.

Claims

1. Solid tumour tracer, its characterized in that: the solid tumor tracking device (910) includes a medical optical tracking system (500); the medical optical tracing system (500) is arranged in the solid tumor, and the position of the solid tumor is marked by a visible light tracing technology;

A. the medical optical tracing system (500) comprises a light source (1) and an optical tracing carrier (2);

B. the optical tracing carrier (2) contains light guide material;

C. the light guide material is a light-storing self-luminous material and/or a light guide optical fiber (22) and/or a transparent material;

D. the light emitted by the light source (1) is conducted through the light guide material of the optical tracing carrier (2), and the optical tracing carrier (2) is optically traced.

2. The solid tumor tracking device of claim 1, wherein: the solid tumor tracking device (910) includes a visualization mechanism (4).

3. The solid tumor tracking device of claim 1, wherein: the solid tumor tracing device (910) comprises a displacement prevention mechanism (910-1).

4. The solid tumor tracking device of claim 1, wherein: the solid tumor tracking device (910) includes a delivery mechanism (910-2).

5. The solid tumor tracking device of claim 3, wherein: the anti-displacement mechanism (910-1) is in a hook-shaped structure, and/or a horn-shaped structure, and/or a dumbbell-shaped structure, and/or a spiral spring-shaped structure, and/or a nail-shaped structure when in a working state.

6. The solid tumor tracking device of claim 5, wherein: the anti-displacement mechanism (910-1) is in a hook-shaped structure and at least comprises 1 positioning hook (910-11).

7. The solid tumor tracking device of claim 6, wherein: the anti-displacement mechanism (910-1) comprises 2 positioning hooks (910-11).

8. The solid tumor tracking device of claim 6, wherein: the anti-displacement mechanism (910-1) is made of shape memory alloy, is in a linear structure in vitro, and is restored to a set hook-shaped structure, and/or a horn-shaped structure, and/or a dumbbell-shaped structure, and/or a spiral spring-shaped structure, and/or a nail-shaped structure under the action of body temperature after entering a human body.

9. The solid tumor tracking device of claim 3, wherein: the anti-displacement mechanism (910-1) is made of a developing material, and forms a developing mechanism (4) for developing under X-ray, MRI and/or B-ultrasonic.

10. The solid tumor tracking device of claim 4, wherein: the delivery mechanism (910-2) includes a pushing mechanism (910-21) and a delivery sheath (910-22).

11. The solid tumor tracking device of claim 10, wherein: an anti-migration mechanism (910-1) is disposed within the delivery sheath (910-22), the push mechanism (910-21) capable of pushing the anti-migration mechanism (910-1) out of the delivery sheath (910-22) and into a solid tumor.

12. The solid tumor tracking device of claim 1, wherein: the light source (1) is an LED light source (11), and/or a medical cold light source (12), and/or natural light.

13. The solid tumor tracking device of claim 1, wherein: the color of the light emitted by the light source (1) can be set according to the background color or the penetration requirement.

14. The solid tumor tracking device of claim 1, wherein: the light source (1) is of a blinking type.

15. The solid tumor tracking device of claim 1, wherein: the intensity of the light emitted by the light source (1) can be set.

16. The solid tumor tracking device of claim 12, wherein: the LED light source (11) is arranged in vivo and/or in vitro.

17. The solid tumor tracking device of claim 1, wherein: the optical tracing carrier (2) is a light-storing self-luminous tracing carrier (21).

18. The solid tumor tracking device of claim 17, wherein: the light-storing and self-luminous tracing carrier (21) contains a light-storing and self-luminous body (21-1) and a protective carrier (21-2).

19. The solid tumor tracking device of claim 18, wherein: the protective carrier (21-2) is made of transparent light guide materials, and the light storage self-luminous body (21-1) is arranged in the protective carrier (21-2) in a sealing mode.

20. The solid tumor tracking device of claim 1, wherein: the optical tracing carrier (2) is a light guiding optical fiber (22).

21. The solid tumor tracking device of claim 20, wherein: the light-guiding optical fiber (22) has a non-smooth surface (22-1).

22. The solid tumor tracking device of claim 21, wherein: the non-smooth surface (22-1) is a non-smooth surface (22-11) that is reflective, and/or scattering.

23. The solid tumor tracking device of claim 22, wherein: the light guide optical fiber (22) is provided with a light outlet (22-2) in an intermittent manner.

24. The solid tumor tracking device of claim 23, wherein: the light guide optical fibers (22) are woven into a net shape, and light outlets (22-2) are distributed at different positions in a scattered manner.

25. The solid tumor tracking device of claim 20, wherein: the surface of the light guide optical fiber (22) contains a coating (3).

26. The solid tumor tracking device of claim 20, wherein: the optical tracing carrier (2) is provided with a developing mechanism (4), and the developing mechanism (4) performs development under X-ray, MRI and/or B-ultrasonic.

27. The solid tumor tracking device of claim 3, wherein: the optical tracing carrier (2) is made of a flexible medical material and is arranged on the outer surface of the displacement prevention mechanism (910-1).

28. The solid tumor tracking device of claim 1, wherein: the optical tracing carrier (2) is a light guide optical fiber (22), the near end of the light guide optical fiber (22) is connected with a light guide joint (26), the far end of the light guide optical fiber (22) is connected and fixed on the anti-displacement mechanism (910-1), and the light outlet (22-2) of the light guide optical fiber (22) is arranged on the anti-displacement mechanism (910-1) to trace the anti-displacement mechanism (910-1).

29. The solid tumor tracking device of claim 28, wherein: the light guide optical fiber (22) is provided with a non-smooth surface (22-1), a light outlet (22-2) is formed in the side face of the light guide optical fiber (22), and the light guide optical fiber (22) is used for integrally tracing the anti-displacement mechanism (910-1).

30. A solid tumor tracking apparatus as claimed in claim 29, wherein: the light guide optical fiber (22) is made of a flexible medical material and is fixedly connected to the anti-displacement mechanism (910-1), and when the anti-displacement mechanism (910-1) deforms, the light guide optical fiber (22) deforms along with the anti-displacement mechanism (910-1).

31. The solid tumor tracking device of claim 1, wherein: light source (1) of medical optical tracing system (500) is LED light source (11), optical tracing carrier (2) are made by transparent material, the luminous end (11-1) of LED light source (11) sets up on optical tracing carrier (2), with optical tracing carrier (2) set up together on preventing aversion mechanism (910-1), it is right prevent aversion mechanism (910-1) and carry out the spike.

32. A solid tumor tracking apparatus as claimed in claim 31, wherein: the LED light source (11) comprises a light emitting end (11-1), a circuit system (11-2), a driving board (11-3) and a power supply (11-4); the light-emitting end (11-1) is connected with the driving board (11-3) and the power supply (11-4) through the circuit system (11-2), under the control of the driving board (11-3), the power supply (11-4) supplies power to the light-emitting end (11-1) through the circuit system (11-2), and the light-emitting end (11-1) emits light; the driving board (11-3) and the power supply (11-4) are arranged outside the body, and the light-emitting end (11-1) is arranged inside the body and traces the anti-displacement mechanism (910-1).

33. The solid tumor tracking device of claim 32, wherein: the circuit system (11-2) is a flexible circuit board (11-21), the light emitting ends (11-1) of the LED light sources (11) are dispersedly arranged on the flexible circuit board (11-21) and encapsulated in the optical tracing carrier (2) to form an LED lamp strip, an LED lamp net or an LED lamp ball, and the LED lamp strip, the LED lamp net or the LED lamp ball is arranged on the anti-displacement mechanism (910-1) to trace the anti-displacement mechanism (910-1).

34. The solid tumor tracking device of claim 28, wherein: the light-emitting end (11-1) of the LED light source (11) is arranged on the anti-displacement mechanism (910-1), the optical tracing carrier (2) is made of transparent materials and coated outside, and light rays emitted by the light-emitting end (11-1) trace the anti-displacement mechanism (910-1).

35. A solid tumor tracking apparatus as claimed in claim 34, wherein: the light-emitting ends (11-1) are dispersedly arranged on the anti-displacement mechanism (910-1) and carry out integral tracing on the anti-displacement mechanism (910-1).

36. A solid tumor tracking apparatus as claimed in claim 35, wherein: circuit system (11-2) are flexible circuit board (11-21), optical tracer carrier (2) are made by soft transparent material, luminous end (11-1) flexible circuit board (11-21) and development mechanism (4) set up together in optical tracer carrier (2), and set up prevent on the aversion mechanism (910-1), when prevent aversion mechanism (910-1) when taking place to warp, luminous end (11-1), flexible circuit board (11-21), development mechanism (4) and optical tracer carrier (2) are along with prevent aversion mechanism (910-1) and take place to warp.