CN218077794U - Controllable 4-BMA production of feeding and discharging in succession is with extraction enrichment facility - Google Patents

Abstract

The utility model discloses a controllable continuous feeding and discharging extraction and concentration device for 4-BMA production, which comprises an extraction kettle, a concentration kettle, a condenser and an extract liquor recovery tank, wherein the bottom of the extraction kettle is provided with a main discharging pipe, and the output end of the main discharging pipe is connected with an organic phase discharging pipe and a water phase discharging pipe; the top of the concentration kettle is provided with an organic phase feed inlet and an upper layer steam outlet, the organic phase discharge pipe is communicated with the organic phase feed inlet, and the upper layer steam outlet is sequentially communicated with the condenser, the extract liquor recovery tank and the recovered extract liquor feed inlet. Organic phase in the extraction cauldron is arranged to concentrated cauldron in by organic phase row material pipe, ethyl ester extractant evaporation in the concentrated cauldron gets into the condenser, get into the extract recovery jar after the condensation, driving motor drive (mixing) shaft positive and negative rotation in turn, improve the convection effect, promote the evaporation of organic phase in the concentrated cauldron, through the drive sealing plug decline compress tightly sealed opening, make upper chamber and lower floor's chamber separate, make organic continuous row to the upper intracavity, realize continuous feeding, improve production efficiency.

Description

Controllable 4-BMA production of feeding and discharging in succession is with extraction enrichment facility

Technical Field

The utility model relates to the technical field of chemical equipment, in particular to a controllable continuous feeding and discharging extraction and concentration device for 4-BMA production.

Background

Meropenem, also known as meropenem, is one of important members of carbapenem antibiotics, has the characteristics of good chemical stability, stability to-beta lactamase and renal dehydropeptidase, and the like, has excellent treatment effect on severe and multiple drug-resistant bacterial infections such as respiratory tract infection, abdominal cavity infection, urinary tract infection, and the like, and is widely applied in the world at present and has wide market prospect.

At present, the synthesis method of meropenem mainly comprises the steps of firstly synthesizing (3S, 4S) -4- [ (R) -1-carboxyethyl ] -3- [ (R) -1-isobutyldimethylsilyloxyethyl ] -2-azetidinone, namely 4-BMA, and then reacting with other raw material intermediates through a series of diazotization, deprotection, hydrogenation, refining and the like to finally obtain the meropenem. Wherein, after the preparation and synthesis of the 4-BMA, an extraction kettle is needed to extract an organic phase, so that the concentration kettle concentrates the organic phase to separate out 4-BMA crystals.

The existing extraction and concentration kettles generally cannot realize continuous work, and the working efficiency of part of the concentration kettles which can realize continuous work is still to be improved. The patent with publication number CN216336694U discloses a continuous evaporation low-temperature liquid material concentration device. When the dense liquid is discharged to needs, the valve between evaporation kettle body and the flowing back cauldron is opened, and the dense liquid enters into the flowing back cauldron, and the valve between evaporation kettle body and the flowing back cauldron is closed after that, and the leakage fluid dram valve of flowing back cauldron is opened, and atmospheric pressure arrives atmospheric pressure back flowing back, so this internal vacuum state that remains throughout of evaporation kettle, can not lose the vacuum because of needs flowing back, therefore reation kettle can work continuously.

The device can be further improved, for example, when the evaporation kettle body heats the liquid to be evaporated and concentrated, the vapor formed after the liquid is boiled is discharged into the evaporator through a pipeline, the liquid in the evaporation kettle body can be gradually reduced and concentrated along with the increase of time, the available space in the evaporation kettle body is gradually increased, the potential utilization value is achieved, but the organic phase solution extracted from the extraction kettle can not be directly added into the kettle body again, the phenomenon that the liquid cannot be boiled due to the reduction of the temperature of the liquid is avoided, and the continuous feeding and concentration operation cannot be realized; in addition, when the device detects that the liquid level of the liquid in the evaporation kettle body is lower than a set value through the liquid level sensor, the controller controls the first valve to be opened, the liquid in the evaporation kettle body flows into the liquid drainage kettle, and the situation that the error is large when the preset concentration value is reached is judged only according to the high level of the liquid level.

SUMMERY OF THE UTILITY MODEL

In view of the above, there is a need to provide an extraction and concentration device for 4-BMA production, which can control and continuously feed and discharge materials.

In order to achieve the purpose, the utility model provides a controllable continuous feeding and discharging 4-BMA production extraction concentration device, which comprises an extraction kettle, a concentration kettle, a condenser and an extract liquor recovery tank, wherein the top of the extraction kettle is provided with an original extract liquor feeding port, a recovered extract liquor feeding port and a material inlet, the bottom of the extraction kettle is provided with a main discharging pipe, and the output end of the main discharging pipe is connected with an organic phase discharging pipe and a water phase discharging pipe; concentrated cauldron top is equipped with organic phase feed inlet and upper steam outlet, organic phase row expects the pipe and communicates with organic phase feed inlet, upper steam outlet passes through upper steam conduit and condenser input intercommunication, the condenser output passes through extract recovery pipe and extract recovery jar intercommunication, extract recovery jar output is through retrieving extract delivery pipe and retrieving extract feed inlet intercommunication, it installs first valve on the extract delivery pipe to retrieve, the extraction cauldron internal fixation has the layering board, the layering board separates concentrated cauldron inner chamber into upper chamber and lower chamber, set up the opening of intercommunication upper chamber and lower chamber on the layering board, be equipped with the sealing plug that can reciprocate in the concentrated cauldron, the sealing plug is used for opening and close the opening with the opening cooperation, lower floor's chamber top one side is equipped with lower floor's steam outlet, lower floor's steam outlet passes through lower floor's steam conduit and upper steam conduit intercommunication, install the second valve on the lower floor's steam conduit.

Preferably, a driving motor is installed at the top of the concentration kettle, a stirring shaft is installed at the output end of the driving motor through a coupling, the upper part of the stirring shaft is rotatably and hermetically installed at the top of the concentration kettle, the lower end of the stirring shaft is located in the concentration kettle and is rotatably and hermetically installed on the layered plate through a sealing bearing, a nut seat is sequentially installed on the stirring shaft from top to bottom, an upper stirring blade and a lower stirring blade are located in an upper cavity, the lower stirring blade is located in a lower cavity, a guide rod is fixed in the extraction kettle and is arranged in parallel with the stirring shaft, a threaded section is arranged on the stirring shaft, the nut seat is in threaded installation on the threaded section and can move to the lower part of the threaded section, the nut seat is slidably installed on the guide rod, a lifting frame is fixedly connected on the nut seat, a guide sleeve is fixed on the lifting frame, a lifting rod is slidably installed in the guide sleeve, the lower end of the lifting rod is fixedly connected with the top of the lifting rod, a limiting plate is fixed on the top of the lifting rod, a spring seat is fixed on the lifting rod, and a pressure spring is sleeved on the lifting rod, and the upper and lower ends of the lifting rod are respectively abutted against the guide sleeve and the spring seat.

Preferably, the sealing plug is of a frustum shape.

Preferably, install upper liquid level detector, lower floor's liquid level detector and density detector on the concentrated cauldron, upper liquid level detector is used for detecting the liquid level of upper intracavity liquid, and lower floor's liquid level detector is used for detecting the liquid level of lower intracavity liquid, and density detector is used for detecting the concentration of lower intracavity liquid.

Preferably, a main discharge valve and a layered view mirror are installed on the main discharge pipe.

Preferably, a vacuum pump is installed on the upper layer steam pipeline.

Preferably, the outer wall of the concentration kettle is provided with a jacket, one side of the upper part of the jacket is provided with a heat medium inlet, and one side of the lower part of the jacket is provided with a heat medium outlet.

Preferably, the organic phase discharge pipe is provided with a third valve, and the aqueous phase discharge pipe is provided with a fourth valve.

Preferably, the sealing plug moves between the layering plate and the upper stirring blade.

Preferably, the bottom of the concentration kettle is provided with a discharge opening, and a fifth valve is arranged at the discharge opening.

Compared with the prior art, the technical scheme has the following beneficial effects:

1. the organic phase in the extraction kettle is discharged into an organic phase feed inlet and a concentration kettle from a main discharge pipe and an organic phase discharge pipe, an ethyl ester extractant in the concentration kettle is evaporated and enters a condenser, the ethyl ester extractant is condensed by the condenser and then enters an extract liquor recovery tank from an extract liquor recovery pipe, a first valve is opened, the extract liquor recovered in the extract liquor recovery tank can be conveyed to the extract liquor recovery feed inlet and the extraction kettle from a recovered extract liquor discharge pipe, and the next material can be conveniently extracted;

2. the driving motor drives the stirring shaft to rotate forward and backward alternately, drives the sealing plug to move up and down to stir the organic phase, and drives the upper-layer stirring blade and the lower-layer stirring blade to stir the organic phase in the concentration kettle, so that the convection effect can be improved, and the evaporation of the organic phase in the concentration kettle is promoted;

3. when the liquid level drops to be lower than the lower layer liquid level detector, the driving motor drives the sealing plug to drop to tightly press the sealing opening, so that the upper layer cavity is separated from the lower layer cavity, steam in the lower layer cavity is discharged by the lower layer steam exhaust pipe, and at the moment, the third valve can be opened again, so that the organic phase is discharged to the organic phase feeding hole and the upper layer cavity from the main material discharge pipe and the organic phase material discharge pipe; when the density detector detects that the liquid concentration in the lower layer cavity reaches a preset value, the fifth valve can be opened to discharge the 4-BMA material in the lower layer cavity, so that continuous feeding is realized, and the production efficiency is improved;

4. after the material discharge of lower floor's intracavity, driving motor antiport, under the promotion of pressure spring elastic restoring force, along with the rotation of (mixing) shaft, on the screw thread section is screwed in again to the nut seat, the opening is kept away from in the rise of nut seat drive sealing plug for upper chamber and lower floor's chamber intercommunication, the liquid of upper intracavity gets into lower floor's intracavity by the opening, can continue to add the organic phase to organic phase feed inlet, until the liquid level reaches and predetermines the liquid level interval, realize continuous feeding, improve production efficiency.

Drawings

Fig. 1 is a schematic structural diagram of an embodiment of the present invention;

FIG. 2 is a schematic diagram of a configuration of a concentrating tank;

FIG. 3 is another state diagram of the thickening tank;

FIG. 4 is an enlarged view of a portion of FIG. 3 at A;

in the figure, 1, an extraction kettle; 2. a concentration kettle; 3. a condenser; 4. an extract liquor recovery tank; 5. a raw extract liquid feeding port; 6. a feed inlet for recovered extract; 7. a material inlet; 8. a main discharging pipe; 9. an organic phase discharge pipe; 10. a water phase discharge pipe; 11. an organic phase feed port; 12. an upper steam outlet; 13. an upper steam line; 14. an extract liquid recovery pipe; 15. an extract liquor recovery discharge pipe; 16. a first valve; 17. a laminate; 18. an upper cavity; 19. a lower cavity; 20. an opening; 21. a sealing plug; 22. a lower layer steam outlet; 23. a lower steam line; 24. a second valve; 25. a drive motor; 26. a stirring shaft; 27. sealing the bearing; 28. a nut seat; 29. an upper layer stirring blade; 30. a lower layer of stirring blades; 31. a threaded segment; 32. a guide rod; 33. a lifting frame; 34. a guide sleeve; 35. a lifting rod; 36. a limiting plate; 37. a spring seat; 38. a pressure spring; 39. an upper level detector; 40. a lower level detector; 41. a density detector; 42. a main discharge valve; 43. layering sight glasses; 44. a vacuum pump; 45. a jacket; 46. a heating medium inlet; 47. a heating medium outlet; 48. a third valve; 49. a fourth valve; 50. a discharge opening; 51. and a fifth valve.

Detailed Description

In order to make the aforementioned objects, features and advantages of the present invention more comprehensible, embodiments accompanied with figures are described in detail below. In the following description, numerous specific details are set forth in order to provide a thorough understanding of the present invention. The invention may be embodied in many other forms different from those described herein and similar modifications may be made by those skilled in the art without departing from the spirit and scope of the invention and, therefore, the invention is not to be limited to the specific embodiments disclosed below.

Referring to fig. 1 to 4, an embodiment of the present application provides an extraction and concentration apparatus for 4-BMA production with controllable and continuous feeding and discharging, including an extraction kettle 1, a concentration kettle 2, a condenser 3 and an extract recovery tank 4, wherein the top of the extraction kettle 1 is provided with an original extract feed inlet 5, a recovered extract feed inlet 6 and a material inlet 7, the bottom of the extraction kettle 1 is provided with a main discharge pipe 8, and an output end of the main discharge pipe 8 is connected with an organic phase discharge pipe 9 and a water phase discharge pipe 10; the top of the concentration kettle 2 is provided with an organic phase feed inlet 11 and an upper layer steam outlet 12, an organic phase discharge pipe 9 is communicated with the organic phase feed inlet 11, the upper layer steam outlet 12 is communicated with the input end of a condenser 3 through an upper layer steam pipeline 13, the output end of the condenser 3 is communicated with an extraction liquid recovery tank 4 through an extraction liquid recovery pipe 14, the output end of the extraction liquid recovery tank 4 is communicated with a recovered extraction liquid feed inlet 6 through a recovered extraction liquid discharge pipe 15, a first valve 16 is installed on the recovered extraction liquid discharge pipe 15, a layering plate 17 is fixed in the extraction kettle 1, the inner cavity of the concentration kettle 2 is divided into an upper layer cavity 18 and a lower layer cavity 19 through the layering plate 17, an opening 20 communicating the upper layer cavity 18 and the lower layer cavity 19 is arranged on the layering plate 17, a sealing plug 21 capable of moving up and down is arranged in the concentration kettle 2, the sealing plug 21 is matched with the opening 20 to open and close the opening 20, one side of the top of the lower layer cavity 19 is provided with a lower layer steam outlet 22, the lower layer steam outlet 22 is communicated with the upper layer steam pipeline 13 through a lower layer steam pipeline 23, and a second valve 24 is installed on the lower layer steam pipeline 23. In order to improve the concentration efficiency and avoid the problem that the steam is blocked and cannot be smoothly discharged, the openings 20 can be arranged in a plurality, the total area of the openings 20 is increased by increasing the number of the openings 20, and the steam is convenient to be discharged upwards.

In order to improve the liquidity of liquid in the concentration kettle 2 and further improve the concentration efficiency, simultaneously, the sealing plug 21 is driven to move up and down, the driving motor 25 is installed at the top of the concentration kettle 2, the driving motor 25 selects a servo motor, the output end of the driving motor 25 is provided with the stirring shaft 26 through a coupler, the upper part of the stirring shaft 26 is rotatably and hermetically installed at the top of the concentration kettle 2, the upper part of the stirring shaft 26 can be hermetically connected with the concentration kettle 2 through a filler, the lower end of the stirring shaft 26 is located in the concentration kettle 2 and is rotatably and hermetically installed on the layered plate 17 through a sealing bearing 27, the stirring shaft 26 is sequentially provided with the nut seat 28, the upper stirring blade 29 and the lower stirring blade 30 from top to bottom, the upper stirring blade 29 is located in the upper cavity 18, the lower stirring blade 30 is located in the lower cavity 19, the extraction kettle 1 is fixedly provided with the guide rod 32, the guide rod 32 is parallel to the stirring shaft 26, the stirring shaft 26 is provided with the threaded section 31, the nut seat 28 is threadedly installed on the threaded section 31 and can move to the lower part below the threaded section 31, the nut seat 28 is slidably installed on the guide rod 32, the nut seat 28 is fixedly connected with the lifting frame 33, the guide sleeve 34, the guide rod 34 is fixedly connected with the limiting spring seat 35, the limiting plate 35, the limiting spring seat 35 and the limiting plate 35, the limiting spring seat 35 is connected with the limiting plate 35, and the limiting spring seat 35, and the limiting plate 35 are respectively connected with the limiting plate 35.

To improve the sealing effect of the opening 20, the sealing plug 21 is provided in the form of a frustum. A frustoconical sealing plug 21 may enter the opening 20, substantially contacting the opening 20 and sealing the opening 20.

In order to facilitate the detection of the liquid levels of the upper chamber 18 and the lower chamber 19 and the concentration of the liquid in the concentration tank 2, an upper liquid level detector 39, a lower liquid level detector 40 and a density detector 41 are installed on the concentration tank 2, the upper liquid level detector 39 is used for detecting the liquid level of the liquid in the upper chamber 18, the lower liquid level detector 40 is used for detecting the liquid level of the liquid in the lower chamber 19, and the density detector 41 is used for detecting the concentration of the liquid in the lower chamber 19. The upper layer liquid level detector 39 and the lower layer liquid level detector 40 both adopt side-mounted capacitive liquid level sensors. The density detector 41 is a tuning fork type liquid density sensor, and may be an ultrasonic density sensor, a capacitance type liquid density sensor, or the like.

In order to discharge the materials in the extraction kettle 1 and observe the critical line of the organic phase and the oil phase, a main discharge valve 42 and a layered sight glass 43 are arranged on the main discharge pipe 8.

In order to facilitate the evacuation and steam delivery of the concentrating still 2, a vacuum pump 44 is installed on the upper steam pipeline 13.

In order to heat the concentration kettle 2 conveniently, a jacket 45 is arranged on the outer wall of the concentration kettle 2, a heating medium inlet 46 is arranged on one side of the upper part of the jacket 45, and a heating medium outlet 47 is arranged on one side of the lower part of the jacket 45. A heating cavity is formed between the jacket 45 and the concentration kettle 2, a heating medium is introduced into the heating medium inlet 46, and the heating medium after heat exchange is discharged from a heating medium outlet 47.

For the purpose of controlling the discharge of the organic phase, a third valve 48 is provided in the organic phase discharge pipe 9, and for the purpose of controlling the discharge of the aqueous phase, a fourth valve 49 is provided in the aqueous phase discharge pipe 10.

In order to avoid contact interference with the upper stirring blade 29 when the sealing plug 21 moves up and down, the sealing plug 21 is arranged to move between the layered plate 17 and the upper stirring blade 29.

In order to discharge the concentrated materials in the concentration kettle 2 conveniently, a discharge opening 50 is arranged at the bottom of the concentration kettle 2, and a fifth valve 51 is arranged at the discharge opening 50.

Each electrical component in this embodiment all connects same PLC control system, and PLC control system has preset control program, and the work of relevant electrical component can be controlled to the accessible control program.

The working steps of the embodiment are as follows:

s1, adding an extraction liquid into an extraction kettle 1 from an original extraction liquid feeding port 5, adding a mixed material to be extracted into the extraction kettle 1 from a material inlet 7, and starting up a stirring system of the extraction kettle 1; after standing and phase splitting, discharging;

s2, opening a main discharge valve 42 and a fourth valve 49, firstly discharging a water phase, discharging the water phase from a main discharge pipe 8 and a water phase discharge pipe 10, observing a layered viewing mirror 43, switching the valves after observing an organic phase, closing the fourth valve 49, opening a third valve 48, and discharging the organic phase from the main discharge pipe 8 and an organic phase discharge pipe 9 to an organic phase feed inlet 11 and a concentration kettle 2;

s3, heating medium is introduced into the jacket 45 to heat the concentration kettle 2, the driving motor 25 drives the stirring shaft 26 to rotate in a positive and negative alternating mode, the nut seat 28 moves up and down under the guiding action of the guide rod 32 to drive the sealing plug 21 to move up and down to stir the organic phase, the number of turns of the stirring shaft 26 rotating in the positive and negative alternating mode is constant, the nut seat 28 cannot be separated from the thread section 31 all the time, and the upper-layer stirring blade 29 and the lower-layer stirring blade 30 stir the organic phase in the concentration kettle 2;

s4, detecting the highest liquid level in the concentration kettle 2 by the upper liquid level detector 39, stopping adding the organic phase after reaching a preset highest liquid level interval, and closing the third valve 48;

s5, vacuumizing the inner cavity of the concentration kettle 2 by a vacuum pump 44 through an upper steam exhaust pipe; the ethyl ester extractant in the concentration kettle 2 is firstly evaporated and enters the condenser 3 from an upper steam exhaust pipe, the extractant is condensed by the condenser 3 and then enters the extraction liquid recovery tank 4 from the extraction liquid recovery pipe 14, the first valve 16 is opened, the extraction liquid recovered in the extraction liquid recovery tank 4 can be conveyed to the extraction liquid recovery inlet 6 and the extraction kettle 1 from the extraction liquid recovery outlet pipe 15, and the next material is extracted;

s6, along with the continuous discharge of the liquid in the concentration kettle 2 in a steam form, the liquid level in the concentration kettle 2 is gradually reduced, when the liquid level is reduced to be lower than the layering plate 17, the liquid is located in the lower-layer cavity 19, and the steam enters the upper-layer cavity 18 through the opening 20; when the liquid level drops to be lower than the lower liquid level detector 40, the lower liquid level detector 40 detects a signal and sends the signal to a PLC control system, the PLC control system controls a sub-driving motor 25 to output power in a single rotation direction, the driving motor 25 drives a nut seat 28, a lifting frame 33, a lifting rod 35 and a sealing plug 21 to sequentially descend, when the nut seat 28 is about to move out of a threaded section 31, the sealing plug 21 is in contact with an opening 20, then the nut seat 28 continues to descend, a pressure spring 38 compresses, the sealing plug 21 tightly presses and seals the opening 20, so that an upper layer cavity 18 is separated from a lower layer cavity 19, a second valve 24 is opened, and steam in the lower layer cavity 19 is discharged to an upper layer exhaust pipe through a lower layer exhaust pipe and enters a condenser 3 through a vacuum pump 44;

s7, after the opening 20 is closed by the sealing plug 21, the third valve 48 can be opened again, so that the organic phase is discharged from the main discharge pipe 8 and the organic phase discharge pipe 9 to the organic phase feed port 11 and the upper cavity 18;

s8, detecting the liquid level in the upper layer cavity 18 by the upper layer liquid level detector 39, and stopping feeding when a preset liquid level interval is reached; at the moment, the upper layer cavity 18 and the lower layer cavity 19 are heated simultaneously, steam in the upper layer cavity 18 is discharged from the upper layer steam exhaust pipe, and steam in the lower layer cavity 19 is discharged from the lower layer steam exhaust pipe to the upper layer steam exhaust pipe; when the density detector 41 detects that the liquid concentration of the lower cavity 19 reaches a preset value, a signal is sent to the PLC control system, and at the moment, the fifth valve 51 can be opened to discharge the 4-BMA material in the lower cavity 19;

s9, after the 4-BMA material in the lower layer cavity 19 is discharged, the PLC control system controls the driving motor 25 to rotate reversely, the nut seat 28 is tightly attached to the lower end of the threaded section 31 under the pushing of the elastic restoring force of the pressure spring 38, the nut seat 28 is screwed into the threaded section 31 again along with the rotation of the stirring shaft 26, the nut seat 28 drives the sealing plug 21 to ascend and be away from the opening 20, the upper layer cavity 18 is communicated with the lower layer cavity 19, the liquid in the upper layer cavity 18 enters the lower layer cavity 19 from the opening 20, the organic phase is continuously added into the organic phase feeding hole 11 until the liquid level reaches a preset liquid level interval, continuous feeding and discharging are achieved, and the production efficiency is improved.

All possible combinations of the technical features in the above embodiments may not be described for the sake of brevity, but should be considered as being within the scope of the present disclosure as long as there is no contradiction between the combinations of the technical features.

The above embodiments only represent several embodiments of the present invention, and the description thereof is specific and detailed, but not to be construed as limiting the scope of the present invention. It should be noted that, for those skilled in the art, without departing from the spirit of the present invention, several variations and modifications can be made, which are within the scope of the present invention. Therefore, the protection scope of the present invention should be subject to the appended claims.

In the description of the present invention, it is to be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", "axial", "radial", "circumferential", and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of description and for simplicity of description, and do not indicate or imply that the device or element referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus, should not be construed as limiting the present invention.

Furthermore, the terms "first", "second" and "first" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or to implicitly indicate the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include at least one such feature. In the description of the present invention, "a plurality" means at least two, e.g., two, three, etc., unless specifically limited otherwise.

In the present invention, unless otherwise explicitly specified or limited, the terms "mounted," "connected," "secured," and the like are to be construed broadly, e.g., as being fixedly connected, detachably connected, or integrated; can be mechanically or electrically connected; they may be directly connected or indirectly connected through intervening media, or they may be connected internally or in any other suitable relationship, unless expressly stated otherwise. The specific meaning of the above terms in the present invention can be understood according to specific situations by those skilled in the art.

Claims (10)

1. The extraction and concentration device for the 4-BMA production with controllable and continuous feeding and discharging comprises an extraction kettle (1), a concentration kettle (2), and is characterized by further comprising a condenser (3) and an extract recovery tank (4), wherein the top of the extraction kettle (1) is provided with an original extract feed inlet (5), a recovered extract feed inlet (6) and a material inlet (7), the bottom of the extraction kettle (1) is provided with a main discharging pipe (8), and the output end of the main discharging pipe (8) is connected with an organic phase discharging pipe (9) and a water phase discharging pipe (10); an organic phase feed inlet (11) and an upper layer steam outlet (12) are arranged at the top of the concentration kettle (2), an organic phase discharge pipe (9) is communicated with the organic phase feed inlet (11), the upper layer steam outlet (12) is communicated with the input end of a condenser (3) through an upper layer steam pipeline (13), the output end of the condenser (3) is communicated with an extraction liquid recovery tank (4) through an extraction liquid recovery pipe (14), the output end of the extraction liquid recovery tank (4) is communicated with a recovered extraction liquid feed inlet (6) through a recovered extraction liquid discharge pipe (15), a first valve (16) is arranged on the recovered extraction liquid discharge pipe (15), a layered plate (17) is fixed in the extraction kettle (1), the inner cavity of the concentration kettle (2) is divided into an upper layer cavity (18) and a lower layer cavity (19) through the layered plate (17), an opening (20) for communicating the upper layer cavity (18) and the lower layer cavity (19) is formed in the layered plate (17), a sealing plug (21) capable of moving up and down is arranged in the concentration kettle (2), and the sealing plug (21) is matched with the opening (20) for opening and closing the opening (20); one side of the top of the lower layer cavity (19) is provided with a lower layer steam outlet (22), the lower layer steam outlet (22) is communicated with the upper layer steam pipeline (13) through a lower layer steam pipeline (23), and a second valve (24) is arranged on the lower layer steam pipeline (23).

2. The extraction and concentration device for controllable and continuous feeding and discharging 4-BMA production according to claim 1, wherein a driving motor (25) is installed on the top of the concentration kettle (2), a stirring shaft (26) is installed at the output end of the driving motor (25) through a coupler, the upper portion of the stirring shaft (26) is rotatably and hermetically installed on the top of the concentration kettle (2), the lower end of the stirring shaft (26) is located in the concentration kettle (2) and is rotatably and hermetically installed on the layered plate (17) through a sealing bearing (27), a nut seat (28), an upper stirring blade (29) and a lower stirring blade (30) are sequentially installed on the stirring shaft (26) from top to bottom, the upper stirring blade (29) is located in the upper cavity (18), the lower stirring blade (30) is located in the lower cavity (19), a guide rod (32) is fixed in the extraction kettle (1), the guide rod (32) and the stirring shaft (26) are arranged in parallel, a threaded section (31) is arranged on the stirring shaft (26), a nut seat (28) is threadedly installed on the threaded section (31) and can move to the lower part of the threaded section (31), the nut seat (28) is slidably installed on the guide rod (34), a lifting frame (34) is fixedly connected with a lifting frame (34), and a lifting frame (34), the lower end of the lifting rod (35) is fixedly connected with the sealing plug (21), the top of the lifting rod (35) is fixedly provided with a limiting plate (36), a spring seat (37) is fixed on the lifting rod (35), a pressure spring (38) is sleeved on the lifting rod (35), and the upper end and the lower end of the pressure spring (38) are respectively abutted to the guide sleeve (34) and the spring seat (37).

3. The apparatus for the extractive concentration for 4-BMA production with controllable and continuous feeding and discharging as claimed in claim 2, wherein the sealing plug (21) is of a frustum shape.

4. The extraction and concentration device for 4-BMA production with controllable and continuous feeding and discharging of materials according to claim 1, wherein an upper liquid level detector (39), a lower liquid level detector (40) and a density detector (41) are installed on the concentration kettle (2), the upper liquid level detector (39) is used for detecting the liquid level in the upper cavity (18), the lower liquid level detector (40) is used for detecting the liquid level in the lower cavity (19), and the density detector (41) is used for detecting the concentration of the liquid in the lower cavity (19).

5. The extraction and concentration device for 4-BMA production with controllable and continuous feeding and discharging according to claim 1, wherein the main discharging pipe (8) is provided with a main discharging valve (42) and a layered view mirror (43).

6. The apparatus for controlled continuous feed and discharge of extraction and concentration for 4-BMA production according to claim 1, wherein a vacuum pump (44) is installed on the upper steam pipe (13).

7. The extraction and concentration device for 4-BMA production with controllable and continuous feeding and discharging according to claim 1, wherein a jacket (45) is installed on the outer wall of the concentration kettle (2), a heating medium inlet (46) is arranged on one side of the upper part of the jacket (45), and a heating medium outlet (47) is arranged on one side of the lower part of the jacket (45).

8. The apparatus for the extractive concentration of 4-BMA production with controllable and continuous feeding and discharging according to claim 1, wherein a third valve (48) is installed on the organic phase discharging pipe (9), and a fourth valve (49) is installed on the aqueous phase discharging pipe (10).

9. The apparatus for the extractive concentration of 4-BMA production with controllable and continuous feeding and discharging of materials according to claim 1, wherein the sealing plug (21) is movable between the layered plate (17) and the upper stirring blade (29).

10. The extraction and concentration device for 4-BMA production with controllable and continuous feeding and discharging according to claim 1, wherein the bottom of the concentration kettle (2) is provided with a discharge opening (50), and a fifth valve (51) is arranged at the discharge opening (50).

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