CN218067657U

CN218067657U - Fecal occult blood detection reagent bottle

Info

Publication number: CN218067657U
Application number: CN202220509173.6U
Authority: CN
Inventors: 雍学安
Original assignee: Hunan Lituo Biotechnology Co ltd; Zhuhai Lituo Biotechnology Co ltd
Current assignee: Hunan Lituo Biotechnology Co ltd; Zhuhai Lituo Biotechnology Co ltd
Priority date: 2022-03-09
Filing date: 2022-03-09
Publication date: 2022-12-16
Anticipated expiration: 2032-03-09

Abstract

The utility model discloses a fecal occult blood detection reagent bottle, which comprises a bottle body provided with a sealing cavity and a detection cavity, wherein the bottle body is provided with a sampling rod inserted into the sealing cavity, and diluent is loaded in the sealing cavity so as to dilute a sample on the sampling rod; the bottle body is provided with a detection rod inserted into the detection cavity, and the detection rod is provided with a reagent strip; the detection cavity is communicated with the sealing cavity through a normally closed hole, and a plug is inserted into the normally closed hole; the detection rod is sucked into the detection cavity, the plug is ejected out of the normally closed hole, so that the detection cavity is communicated with the sealing cavity, and diluent for diluting a sample flows into the detection cavity and is in contact with the reagent strip in the detection cavity. The utility model discloses a just, occult blood detect reagent bottle, excrement and urine sample is kept apart in effective protection, avoids the direct-view contact, avoids exposing the omission, causes the pollution.

Description

Fecal occult blood detection reagent bottle

Technical Field

The utility model belongs to the field of medical equipment, especially, relate to a just occult blood detection reagent bottle.

Background

The fecal occult blood detection is one of the important technologies for early diagnosis of colorectal cancer and population screening, and the colon endoscopy of the patient with positive fecal occult blood can improve the tumor detection rate by 4-6 times, so that the method is the best method for screening high risk populations with colorectal tumor. The annual detection of fecal occult blood has been demonstrated by a number of large-scale cohort studies to significantly reduce the incidence and mortality of colorectal cancer in humans. Fecal occult blood detection is recommended as the colorectal cancer screening technology of the most main population by a plurality of authoritative organizations such as American cancer society, early diagnosis and early treatment projects of colorectal cancer of the national ministry of health of China, and digestive diseases of the Chinese medical society.

In the conventional fecal occult blood detection, a subject needs to take stool for inspection and the professional in a hospital detects the stool. However, due to the high requirements for specimen preservation and transportation in stool collection and examination, the hospital participants often ignore or do not have the intention to do so without examining the stool. Therefore, in actual screening and physical examination of people, the stool sampling and submitting rate is low. In a colorectal cancer screening test in Hangzhou lower urban areas, shanghai Xuhui areas and Harbin south hilly areas, the excrement delivery rate of community residents is less than 40%. In fact, the operation method of the colloidal gold immunity test paper for detecting the fecal occult blood is very simple, is similar to the early pregnancy test paper, and can be completely detected by community residents at home and judge the result by the community residents.

However, stool tests are significantly different from urine tests: first, feces are more easily contaminated than urine and are unwilling to look directly or touch with them. Secondly, the excrement is solid and needs to be fully dissolved in the liquid before the detection of the immune test paper can be carried out. Again, control of stool sampling volume is more difficult than with urine. Finally, it is necessary to ensure that fecal fluids do not spill during the testing operation, otherwise it is not suitable for home or non-specialized home testing. At present, no instrument suitable for the fecal occult blood self-test exists in the market, and some immune gold-labeled fecal occult blood reagent manufacturers design respective excrement collectors, but the excrement collectors do not have sampling amount control devices and do not comprise detectors, and all detections need to open fecal liquid. At present, fecal occult blood is only carried out in professional medical institutions, and when a professional detects the fecal occult blood, feces is firstly placed in a container with a buffer solution to be dissolved, then the feces solution in the container is poured into a small cup or a small hole, and then a liquid absorption test strip is inserted into the small cup or the small hole to detect the fecal occult blood. The fecal liquid is open during detection, the frequency of direct vision of feces is high, a small cup and a small hole are easy to overturn and overflow and leak the liquid during operation, the operation is carried out by taking gloves, and detection instruments are scattered and not sleeved, so that the detection instruments are inconvenient to carry and transport, and the defects cause that the existing fecal occult blood cannot be automatically determined by non-professionals.

Fecal occult blood is an early warning for digestive tract abnormalities, and when the amount of digestive tract bleeding is small, the appearance of the feces can be changed without abnormalities and can not be identified by naked eyes. Therefore, for patients suspected of having chronic hemorrhage in the digestive tract, fecal occult blood should be checked, which is of great significance for early screening of digestive tract malignant tumors (such as gastric cancer, colorectal cancer, polyp and adenoma). Conventional immunoassay methods hemoglobin detection methods require patients to visit a specialized hospital or physical examination facility and be examined using a sampling tube and a kit. The patient keeps the excrement and urine sample, and medical science inspection personnel use the sampling tube sample, mixes quantitative excrement and urine and stabilizing solution, drips the mixture and adds just occult blood kit, and according to the colloidal gold immunochromatography principle, the mixed liquid is by the test paper strip siphon race plate in the kit, appears the typewriter ribbon, compares with standard colour chart according to the typewriter ribbon colour depth, judges that excrement and urine occult blood is negative or positive.

SUMMERY OF THE UTILITY MODEL

The utility model provides a fecal occult blood detection reagent bottle to solve the complete exposed open technical problem of excrement and urine sample who mentions in the background art.

In order to achieve the above purpose, the utility model discloses a specific technical scheme of just occult blood detect reagent bottle as follows:

a reagent bottle for detecting fecal occult blood comprises a bottle body provided with a sealing cavity and a detection cavity, wherein the bottle body is provided with a sampling rod inserted into the sealing cavity, and diluent is loaded in the sealing cavity to dilute a sample on the sampling rod; the bottle body is provided with a detection rod inserted into the detection cavity, and the detection rod is provided with a reagent strip; the detection cavity is communicated with the sealing cavity through a normally closed hole, and a plug is inserted into the normally closed hole; the detection rod is sucked into the detection cavity, the plug is ejected out of the normally closed hole, so that the detection cavity is communicated with the sealing cavity, and diluent for diluting a sample flows into the detection cavity and is in contact with the reagent strip in the detection cavity.

Furthermore, the detection rod is provided with a detachable blocking piece which is arranged along the direction that the detection rod is inserted into the bottle body; the separation blade is abutted against the edge of the bottle body, so that the detection rod is kept in the detection cavity; and (4) removing the blocking piece, so that the detection rod can be further inserted to eject the plug.

Furthermore, separation blade one end and detection stick integrated into one piece, the other end and body border butt.

Furthermore, a boss for the stop piece to abut against is formed on the bottle body.

Further, the normal closed hole is inserted from keeping away from detection stick one side to the end cap, and the end cap is kept away from detection stick one side and is formed with the chimb, chimb and normal close hole border butt.

Furthermore, the side of the detection rod is provided with an embedding groove, and a reagent strip arranged along the length direction of the detection rod is embedded in the embedding groove.

Furthermore, the bottle body is provided with a positioning hole, a fixing pin is inserted into the positioning hole, and the fixing pin penetrates through the detection rod and is inserted into a limiting hole in the sampling rod.

Further, the bottle includes the transparent body that sets up to observe the reagent strip in detecting the intracavity.

Furthermore, the bottle body forms an insertion hole for inserting the sampling rod, and the insertion hole is connected with the sealing cavity through a communication hole; the middle part of the sampling rod is provided with a sealing part which is connected with the communicating hole in a sealing way.

Furthermore, a pressure lever is formed at the lower end of the detection rod and is used for being abutted to the plug so as to eject the plug from the normally closed hole.

The utility model discloses a just occult blood detect reagent bottle has following advantage:

1. the utility model is designed to effectively protect and isolate the fecal specimen during detection, avoid direct-vision contact, avoid exposure omission and pollution; compared with most detection kits, the detection operation mode is simpler, more convenient and faster, and brings comfortable psychological perception and better operation and use experience to users;

2. the detection rod is inserted, so that the reagent strip can be conveniently inserted or taken out, and the invalid reagent strip can be replaced or installed;

3. through separation blade and fixed pin, carry on spacingly and fixed to sampling stick and detection stick to satisfy and detect the process.

Drawings

FIG. 1 is a schematic view of the structure of a reagent bottle for detecting occult blood in feces according to the present invention;

FIG. 2 is a sectional view of the reagent bottle for detecting occult blood in feces according to the present invention;

FIG. 3 is an exploded view of the reagent bottle for detecting occult blood in feces of the present invention;

FIG. 4 is a schematic structural view of a sampling rod of the present invention;

FIG. 5 is a schematic view of the structure of the detecting rod of the present invention;

FIG. 6 is a schematic view of the bottle body structure of the present invention;

fig. 7 is a schematic view of the plug structure of the present invention;

fig. 8 is a schematic view of the pressing of the fecal occult blood detection reagent bottle of the present invention.

The notation in the figure is:

1. a bottle body; 11. a bottle body; 111. a detection chamber; 112. a jack; 113. a communicating hole; 12. a base; 13. sealing the cavity; 14. a boss; 15. a limiting plate; 2. a sampling rod; 21. a threaded end; 22. a sealing part; 221. a first seal ring; 3. a detection rod; 31. a reagent strip; 32. a baffle plate; 33. a pressure lever; 4. a plug; 41. a convex edge; 42. a second seal ring; 5. a normally closed hole; 6. a fixing pin; 61. a handle.

Detailed Description

In order to better understand the purpose, structure and function of the present invention, the following description is made in detail with reference to the accompanying drawings.

As shown in fig. 1-3, the reagent bottle for detecting occult blood in feces of the present invention comprises a bottle body 1, wherein the bottle body 1 is provided with a detection chamber 111 and a sealing chamber 13. The bottle body 1 is provided with a sampling rod 2 and a detection rod 3.

As shown in FIG. 4, the sampling wand 2 is formed with a press handle at one end and a threaded end 21 at the other end. The sampling rod 2 is held by pressing the handle, so that a sample such as feces is stuck to the threaded end 21 at the end of the sampling rod 2, and then the sampling rod 2 is inserted into the sealed cavity 13 of the bottle body 1.

The body 1 is formed with an insertion hole 112 into which the sampling stick 2 is inserted, and the insertion hole 112 is connected to the sealing chamber 13 through a communication hole 113. The sealed chamber 13 is filled with a diluent. As the sampling wand 2 is inserted into the sealed chamber 13, the sample on the threaded end 21 contacts the diluent in the sealed chamber 13, thereby dissolving the sample in the diluent.

In order to prevent the diluent after diluting the sample from overflowing, the middle part of the sampling rod 2 is formed with a sealing part 22, the outer wall of the sealing part 22 is formed with an annular sealing groove, a first sealing ring 221 is sleeved on the sealing groove, the first sealing ring 221 is clamped between the sealing part 22 and the communication hole 113, and the sealing part 22 and the communication hole 113 are connected in a sealing mode.

In order to prevent the reagent strip 31 from being deteriorated due to moisture or the like caused by the storage environment, the detection rod 3 is inserted into the detection chamber 111 of the vial 1 by being inserted into the vial 1. Referring to FIG. 5, a recessed groove is formed on the side of the detection rod 3, and a reagent strip 31 is embedded in the recessed groove and arranged along the length direction of the detection rod 3. Thereby being convenient for detecting and replacing the reagent strip 31 by inserting and pulling the detection rod 3.

Referring to fig. 1 and 6, the detection cavity 111 is communicated with the sealed cavity 13 through the normally closed hole 5, and since the liquid level of the diluent in the sealed cavity 13 is higher than that of the detection cavity 111, when the normally closed hole 5 is opened, the diluent permeates into the detection cavity 111 from the sealed cavity 13 and contacts with the diluent through the reagent strip 31, so as to obtain an experimental result.

As shown in fig. 2 and 7, a plug 4 is inserted into the normally closed hole 5 to keep the normally closed hole 5 normally closed. A second sealing ring 42 is also sleeved on the plug 4 through an annular groove to seal the normally closed hole 5. With the test stick 3 inserted into the normally closed hole 5, the plug 4 is ejected from the normally closed hole 5, so that the diluent dissolving the sample flows into the test chamber 111 and contacts the reagent strip 31 in the test chamber 111. The bottle body 1 comprises a transparent bottle body 11, so that the reagent strip 31 in the detection cavity 111 can be observed conveniently, and the experimental result can be judged according to the color of the reagent strip 31.

Specifically, the sealed cavity 13 is L-shaped, the detection cavity 111 is 1-shaped, the main body of the sealed cavity 13 is vertically arranged side by side with the detection cavity 111, and the lower end of the sealed cavity 13 horizontally extends to the lower side of the detection cavity 111, so as to set the plug 4 to control the flow of the diluent. And a pressing rod 33 is formed at the lower end of the detection rod 3, and the pressing rod 33 is used for being abutted with the plug 4 so as to eject the plug 4 out of the normally closed hole 5. The plug 4 is inserted into the normally closed hole 5 from one side far away from the detection rod 3, a convex edge 41 is formed on one side far away from the detection rod 3 of the plug 4, and the convex edge 41 is abutted against the edge of the normally closed hole 5 to ensure the insertion depth

The bottle body 1 comprises a bottle body 11 and a base 12, and the bottle body 11 and a bottom cover are also welded into a whole through ultrasonic welding.

As can be seen from the above, the sample rod 2 and the detection rod 3 need to be inserted twice in stages. For the first time, the tail end of the sampling rod 2 is inserted into the sealed cavity 13 to dilute the sample, and the detection rod 3 is inserted into the detection cavity 111 to wait for detection; and secondly, the detection rod 3 is further inserted into the detection cavity 111 and ejects the plug 4 out, the sampling rod 2 is further inserted into the sealing cavity 13, and the diluent is accelerated to enter the detection cavity 111. Therefore, the pressing handle of the detecting rod 3 is provided with a detachable blocking piece 32, the blocking piece 32 is arranged along the direction that the detecting rod 3 is inserted into the bottle body 1, specifically, one end of the blocking piece 32 is integrally formed with the detecting rod 3, the other end of the blocking piece is abutted against the edge of the bottle body 11, so that the detecting rod 3 is kept in the detecting cavity 111, the blocking piece 32 is detached through breaking, and the detecting rod 3 can be further inserted to eject the plug 4. The bottle body 1 is also formed with a boss 14 against which the stopper 32 abuts.

In addition, 1 upper end of bottle is opened there is the locating hole, and the locating hole is pegged graft and is had fixed pin 6, and fixed pin 6 runs through and detects stick 3 to peg graft with the spacing hole on the sampling stick 2, thereby die bottle 1,

detection stick

3, 2 three kinds of locks of sampling stick simultaneously, guarantee that the transportation drops or damages. The fixing pin 6 has a handle 61 formed at an end thereof, and the handle 61 is formed with a notch into which the boss 14 is inserted to radially fix the handle 61 and prevent the handle 61 from rotating.

The bottle body 1 is provided with a limiting plate 15, the limiting plate 15 is positioned between the detection rod 3 and the sampling rod 2, and a first sliding chute and a second sliding chute are respectively formed in the limiting plate 15; a first sliding block is formed on the detection rod 3 and slides along the first sliding groove to limit the insertion depth of the detection rod 3;

in summary, referring to fig. 8, the fixing pin 6 is firstly pulled out, the sampling rod 2 is taken out, feces are collected by the threaded end 21, and then the sampling rod 2 is inserted into the diluent to dilute the sample; then pull out separation blade 32, down press sampling stick 2 and detection stick 3 to the end, disclose below end cap 4, excrement and urine dilutes the mixed flow and enters detection chamber 111 and detect reagent strip 31 and soak the contact and realize the detection reaction to the form that shows that sees through transparent body 11 feedback result.

It is to be understood that the present invention has been described with reference to certain embodiments, and that various changes or equivalents may be substituted for elements thereof by those skilled in the art without departing from the spirit and scope of the invention. In addition, many modifications may be made to adapt a particular situation or material to the teachings of the invention without departing from the essential scope thereof. Therefore, the present invention is not limited to the specific embodiments disclosed herein, and all embodiments falling within the scope of the claims of the present application are intended to be covered by the present invention.

Claims

1. A reagent bottle for detecting fecal occult blood comprises a bottle body provided with a sealing cavity and a detection cavity, and is characterized in that the bottle body is provided with a sampling rod inserted into the sealing cavity, and diluent is loaded in the sealing cavity to dilute a sample on the sampling rod; the bottle body is provided with a detection rod inserted into the detection cavity, and the detection rod is provided with a reagent strip; the detection cavity is communicated with the sealing cavity through a normally closed hole, and a plug is inserted into the normally closed hole; the detection rod is sucked into the detection cavity, the plug is ejected out of the normally closed hole, so that the detection cavity is communicated with the sealing cavity, and diluent for diluting a sample flows into the detection cavity and is in contact with the reagent strip in the detection cavity.

2. The reagent bottle for detecting fecal occult blood according to claim 1, wherein the detection rod is provided with a detachable blocking sheet, and the blocking sheet is arranged along the direction of inserting the detection rod into the bottle body; the baffle plate is abutted against the edge of the bottle body, so that the detection rod is kept in the detection cavity; and (4) removing the blocking piece, so that the detection rod can be further inserted to eject the plug.

3. The fecal occult blood detecting reagent bottle according to claim 2, wherein the blocking piece has one end integrally formed with the detecting rod and the other end abutting against the edge of the bottle body.

4. The fecal occult blood detecting reagent bottle according to claim 2, wherein the bottle body is formed with a boss against which the blocking piece abuts.

5. The fecal occult blood detecting reagent bottle according to claim 1, wherein the plug is inserted into the normally closed hole from the side away from the detecting rod, a convex edge is formed on the side of the plug away from the detecting rod, and the convex edge abuts against the edge of the normally closed hole.

6. The reagent bottle for detecting fecal occult blood according to claim 1, wherein a caulking groove is formed on the side surface of the detection rod, and a reagent strip arranged along the length direction of the detection rod is embedded in the caulking groove.

7. The occult blood detection reagent bottle of claim 1, wherein the bottle body is provided with a positioning hole, a fixing pin is inserted into the positioning hole, and the fixing pin penetrates through the detection rod and is inserted into a limiting hole on the sampling rod.

8. The fecal occult blood detection reagent bottle of claim 1, wherein the bottle body comprises a transparently disposed body to view the reagent strip in the detection chamber.

9. The reagent bottle for detecting fecal occult blood according to claim 1, wherein the bottle body forms an insertion hole for inserting the sampling rod, and the insertion hole is connected with the sealing cavity through a communication hole; the middle part of the sampling rod is provided with a sealing part which is connected with the communicating hole in a sealing way.

10. The fecal occult blood detecting reagent bottle as claimed in claim 1, wherein the lower end of the detecting rod is formed with a pressing rod, the pressing rod is used for abutting against the plug so as to eject the plug from the normally closed hole.