CN218035943U - Fixed flusher that experiment mouse brain tissue was drawn materials - Google Patents
Fixed flusher that experiment mouse brain tissue was drawn materials Download PDFInfo
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- CN218035943U CN218035943U CN202221409061.XU CN202221409061U CN218035943U CN 218035943 U CN218035943 U CN 218035943U CN 202221409061 U CN202221409061 U CN 202221409061U CN 218035943 U CN218035943 U CN 218035943U
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Abstract
The utility model relates to a medical science experiment technical field's a fixed flusher that experiment mouse brain tissue was drawn materials, including fixed flusher and the board of drawing materials, fixed flusher includes shell, elastic membrane, fixer and water pocket, the elastic membrane is established on a side surface of shell, the water pocket sets up the inside at the shell, the one end at the shell is installed to the one end of fixer, draw materials one side of board upper surface and install the lateral wall, the internally mounted of lateral wall has brain groove, the inside of the board of drawing materials is equipped with the ice dish. The liquid outlet amount can be controlled at will by pressing the water sac with the thumb; the head end circular ring can effectively fix brain tissues; through getting to have the lateral wall that can lean on the material board, embedded brain groove can help fixed, upset brain tissue, and the board surface of getting to draw materials can reduce to slide and make things convenient for the memory brain tissue piece of having peeled off for frosting and demarcation, just the utility model discloses simple structure is ingenious, easy to operate, and the practicality is stronger.
Description
Technical Field
The utility model relates to a medical science experiment technical field especially relates to a fixed flusher that experiment mouse brain tissue was drawn materials.
Background
In animal experiments of mouse and rat nervous system disease models, materials are often drawn from specific brain tissue structures. However, the murine brain itself is very small, fragile and easy to liquefy, and the corresponding structures such as hippocampus, substantia nigra and striatum are smaller and more complex, for example, the striatum is wrapped deeply and closely adhered to the peripheral white matter, and the difficulty in separating these nerve nuclei is very high, which is a great obstacle restricting neuroscience research.
Aiming at the problems, people design methods of firstly freezing and then peeling, positioning and slicing and then separating, and carrying out three-dimensional positioning injection on dyes in advance to reduce the separation difficulty, however, the process is more complex and the cost is higher, the traditional empirical peeling of fresh brain still cannot be replaced, but the tool used for peeling is still the separation of the ophthalmological forceps held by two hands, one side is used for assisting in fixing, and the other side is used for peeling, however, the brain tissue is extremely fragile and easy to liquefy, the ophthalmological forceps are blunt and easily clamp the brain tissue, the tissue is difficult to fix so that the other hand can be peeled, the brain tissue is difficult to turn over when being moistened and smooth, in addition, the boundary of part of the structure is difficult to distinguish, other tissues are easy to take due to the quick liquefying, the subsequent detection result is influenced, the conventional corresponding means is to shorten the material taking time and cool the ice dish, and the factors also cause an operator to need a large number of mice to practice the holding of strength, precision, speed and skill, so that the material taking cost is greatly increased, and a fixing flusher for taking materials of the experimental mouse brain tissue is provided.
SUMMERY OF THE UTILITY MODEL
To the above problem, the utility model provides a fixed flusher that experiment mouse brain tissue was drawn materials has and is difficult to turn, fixes brain tissue in solving brain tissue and drawing materials, and the problem of brain tissue liquefaction fast, difficult distinguishment structure.
The technical scheme of the utility model is that: the utility model provides a fixed flusher that experiment mouse brain tissue was drawn materials, includes fixed flusher and gets the material board, fixed flusher includes shell, elastic membrane, fixer and water pocket, the elastic membrane is established at a side surface of shell, the water pocket sets up the inside at the shell, the one end at the shell is installed to the one end of fixer, draw materials one side of board upper surface and install the lateral wall, the internally mounted of lateral wall has the brain groove, the inside of getting the material board is equipped with the ice dish.
In a further technical scheme, the fixer is divided into a vertical rod and a fixing ring, and the fixing ring is circular.
In a further technical scheme, the water bag is filled with ice physiological saline, and one end of the water bag is arranged on the surface of the fixer in the shell.
In a further technical scheme, the surface of the material taking plate is provided with a frosted surface.
In a further technical scheme, an area A, an area B, an area C and an area D are distributed on the surface of the material taking plate.
The beneficial effects of the utility model are that:
the liquid outlet amount can be controlled at will by pressing the water sac with the thumb; the head end circular ring can effectively fix brain tissues and reduce pressure intensity so as to avoid damaging the structure of the brain tissues; the water sac in the handle can extract ice physiological saline to irrigate the surface of the brain tissue for cooling at any time, and can flush the tissue to help distinguish the boundary of a fine nucleus structure, particularly, redundant white matter fibers are easy to attach to a target structure and can be distinguished and effectively removed through flushing; the side wall which can lean against is arranged on the material taking plate, the brain groove is embedded, the brain tissue can be fixed and turned, the surface of the material taking plate is a frosted surface and is divided into subareas, the sliding can be reduced, and the stripped brain tissue fragments can be conveniently memorized;
drawings
FIG. 1 is a sectional view of the front structure of the fastener according to the embodiment of the present invention;
fig. 2 is a sectional view of a side structure of a holder according to an embodiment of the present invention;
fig. 3 is a schematic view of the bottom structure of the fixing device according to the embodiment of the present invention;
FIG. 4 is a schematic view of the upper surface structure of the material drawing plate according to the embodiment of the present invention;
fig. 5 is a schematic front view of a material drawing plate according to an embodiment of the present invention.
Description of reference numerals:
1. a housing; 2. an elastic film; 3. a holder; 4. a water bladder; 5. brain channels; 6. taking a material plate; 7. and (4) a ice dish.
Detailed Description
The embodiments of the present invention will be further explained with reference to the drawings.
The embodiment is as follows:
as shown in fig. 1-5, a fixed flusher of drawing materials of experimental mouse brain tissue, including fixed flusher and the board 6 of drawing materials, fixed flusher includes shell 1, elastic membrane 2, fixer 3 and water pocket 4, and elastic membrane 2 establishes a side surface at shell 1, and water pocket 4 sets up in the inside of shell 1, and the one end at shell 1 is installed to the one end of fixer 3, draws materials one side of board 6 upper surface and installs the lateral wall, and the internally mounted of lateral wall has brain groove 5, draws materials the inside of board 6 and is equipped with ice dish 7.
The working principle of the technical scheme is as follows:
the liquid outlet amount can be controlled at will by pressing the water bag 4 with the thumb by holding the water bag with the left hand; the head end circular ring of the fixer 3 can effectively fix brain tissues and reduce pressure intensity so as to avoid damaging the structure of the fixer; the water sac 4 in the handle can be used for pumping ice physiological saline to irrigate the surface of brain tissue for cooling at any time, and can flush the tissue to help distinguish the boundary of a fine nucleus structure, particularly, redundant white matter fibers are easy to attach to a target structure and can be distinguished and effectively removed through flushing; the lateral wall that can lean on is gone up to the board of drawing materials 6 of design, embeds brain groove 5, can help fixed, upset brain tissue, draws materials the board 6 surface of 6 and for frosting and demarcate the subregion, can reduce to slide and make things convenient for the memory brain tissue piece that strips out.
In another embodiment, as shown in fig. 1, 2 and 3, the fixer 3 is divided into a vertical rod and a fixing ring, and the fixing ring is shaped like a circular ring.
The brain tissue can be effectively fixed and the pressure intensity can be reduced through the fixing ring at one end of the fixer 3 so as to avoid damaging the structure of the fixer, and one end of the vertical rod is arranged in the shell 1, so that the fixer 3 can be supported.
In another embodiment, as shown in fig. 1, 2 and 3, the inside of the water bag 4 is filled with ice saline, and one end of the water bag 4 is provided on the surface of the holder 3 inside the housing 1.
Hold between the fingers through the left hand, the thumb presses water pocket 4 alright the control liquid output volume at will, and the inside water pocket 4 of handle can extract ice normal saline water waters brain tissue surface cooling at any time to can wash the limit that the tissue helps distinguish meticulous nucleus structure, especially unnecessary white matter fibre is attached on target structure easily, through wash alright with distinguishing and effectively rejecting.
In another embodiment, as shown in fig. 4 and 5, the surface of the material-drawing plate 6 is provided with a frosted surface.
The surface of the material taking plate 6 is set to be a frosted surface, so that brain tissue fragments stripped by sliding can be effectively reduced.
In another embodiment, as shown in FIG. 4 and FIG. 5, the material-drawing plate 6 has a distribution of the regions A, B, C and D on the surface thereof.
By taking four areas of the surface of the plate 6, it is possible to facilitate the memory of the brain tissue fragments that have been stripped off.
The above embodiments only express the specific embodiments of the present invention, and the description thereof is specific and detailed, but not construed as limiting the scope of the present invention. It should be noted that, for those skilled in the art, without departing from the spirit of the present invention, several variations and modifications can be made, which are within the scope of the present invention.
Claims (5)
1. The utility model provides a fixed flusher that experimental mouse brain tissue was drawn materials, includes fixed flusher and draw materials board (6), its characterized in that: the fixed flusher comprises a shell (1), an elastic membrane (2), a fixer (3) and a water bag (4), the elastic membrane (2) is arranged on one side surface of the shell (1), the water bag (4) is arranged in the shell (1), one end of the fixer (3) is arranged at one end of the shell (1), one side of the upper surface of a material taking plate (6) is provided with a side wall, the inside of the side wall is provided with a brain groove (5), and the inside of the material taking plate (6) is provided with a ice dish (7).
2. The fixed irrigator for taking experimental rat brain tissue according to claim 1, wherein: the fixer (3) is divided into a vertical rod and a fixing ring, and the fixing ring is in a ring shape.
3. The fixed irrigator for taking experimental rat brain tissue according to claim 2, wherein: the water bag (4) is filled with ice physiological saline, and one end of the water bag (4) is arranged on the surface of the fixer (3) in the shell (1).
4. The fixed irrigator for taking experimental rat brain tissue according to claim 1, wherein: the surface of the material taking plate (6) is provided with a frosted surface.
5. The fixed irrigator for taking experimental mouse brain tissue according to claim 4, wherein: the surface of the material taking plate (6) is distributed with an area A, an area B, an area C and an area D.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202221409061.XU CN218035943U (en) | 2022-06-01 | 2022-06-01 | Fixed flusher that experiment mouse brain tissue was drawn materials |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202221409061.XU CN218035943U (en) | 2022-06-01 | 2022-06-01 | Fixed flusher that experiment mouse brain tissue was drawn materials |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN218035943U true CN218035943U (en) | 2022-12-13 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202221409061.XU Active CN218035943U (en) | 2022-06-01 | 2022-06-01 | Fixed flusher that experiment mouse brain tissue was drawn materials |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN218035943U (en) |
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2022
- 2022-06-01 CN CN202221409061.XU patent/CN218035943U/en active Active
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