CN217973184U - Separation device for extracellular vesicles - Google Patents
Separation device for extracellular vesicles Download PDFInfo
- Publication number
- CN217973184U CN217973184U CN202221928241.9U CN202221928241U CN217973184U CN 217973184 U CN217973184 U CN 217973184U CN 202221928241 U CN202221928241 U CN 202221928241U CN 217973184 U CN217973184 U CN 217973184U
- Authority
- CN
- China
- Prior art keywords
- liquid
- filtration membrane
- way valve
- collecting box
- membrane
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Images
Abstract
The utility model discloses a separator of outer vesicle of cell belongs to biological liquid separation technical field, including the injector, the inside lower extreme of injector is provided with the microfiltration membrane, the inside bottom of injector is the arc, the beneficial effects of the utility model are that through the valve of opening first pipeline and second pipeline, make outer vesicle bubble get into first collecting box and the inside collection of second collecting box, because first filtration membrane and second filtration membrane are the slope form, utilize balanced liquid to be convenient for rush into first collecting box and second collecting box through the first filtration membrane and the second filtration membrane of slope inside, set up first filtration membrane and second filtration membrane into the slope form simultaneously, prevent to block up, make outer vesicle bubble granule slide to first filtration membrane and second filtration membrane slope low side, flow in the middle of the liquid accessible and the upper end, avoid whole blockings up, first separation chamber and second separation chamber are transparent material, make the user discover in time to handle this problem more easily.
Description
Technical Field
The utility model relates to a biological liquid separation technical field specifically says a separator of extracellular vesicle.
Background
Extracellular Vesicles (EVs) refer to vesicular bodies with a double-layer membrane structure that are shed from cell membranes or secreted by cells, and have diameters of 50nm to 2mm, and are widely and stably present in various body fluids, such as peripheral blood, urine, saliva, cerebrospinal fluid, milk, ascites, amniotic fluid, and other body fluids, and carry various biomolecules (including proteins, mRNA, miRNA, and the like) derived from cells, and are important tools for carrying out substance transportation, signal transduction, and physiological functions of cells.
The existing extracellular vesicle filtering device has the following problems:
(1) The biological material remains in the filtering membrane due to the overlarge pore diameter, so that the filtering membrane is easily blocked, and the separation is influenced.
(2) The device needs to be disassembled, cleaned and collected, so that the outer vesicle is easily polluted.
SUMMERY OF THE UTILITY MODEL
An object of the utility model is to provide a separator of extracellular vesicle to propose biomaterial in solving above-mentioned background art because the aperture is too big can remain in filtration membrane, lead to filtration membrane jam easily, influence the separation, need carry out dismouting clearance and collection to the device, lead to outer vesicle to cause the problem of pollution easily.
The technical scheme of the utility model is that: including the injector, the inside lower extreme of injector is provided with the microfiltration membrane, the inside bottom of injector is the arc, the injector bottom is provided with first three-way valve, the upper end of first three-way valve with the connection can be dismantled through luer to the bottom of injector, the lower extreme of first three-way valve is provided with first separation chamber, first separation chamber is transparent material, first separation chamber with the lower extreme of first three-way valve can dismantle the connection through luer, the centre of first three-way valve is provided with the liquid filler, the liquid filler with the connection can be dismantled through luer to the centre of first three-way valve, first three-way valve three-terminal all is equipped with corresponding valve, the inside of first separation chamber is provided with first filtration membrane, first filtration membrane is the tilt state, first separation chamber outside is close to the high-end one side of first filtration membrane slope is provided with first liquid and deposits the case, first liquid is deposited the case and is close to one side of first separation chamber is provided with first liquid conveying device, first liquid conveying device goes out the liquid end with first liquid deposits the case and communicates mutually, first liquid conveying device holds first liquid is close to the imbibition chamber and first liquid absorption mouth intercommunication eminence, and first liquid conveying device upper end is linked together.
Furthermore, a first collecting box is arranged on one side, located at the inclined lower end of the first filtering membrane, of the outside of the first separation cavity, a first pipeline is communicated with the upper end of the first collecting box, the other end of the first pipeline is communicated with the first separation cavity, a communication port is located on the upper side of the inclined lower end of the first filtering membrane, and valves are arranged on the first pipeline and the first liquid conveying pipe.
Further, the bottom of first separation chamber is provided with the second three-way valve, the upper end of second three-way valve with the connection can be dismantled through luer joint in the bottom of first separation chamber, the lower extreme of second three-way valve is provided with the second separation chamber, the second separation chamber is transparent material, the second separation chamber with the connection can be dismantled through luer joint in the lower extreme of second three-way valve, be provided with the liquid filler in the middle of the second three-way valve, the liquid filler with the connection can be dismantled through luer joint in the middle of the second three-way valve, the three-end of second three-way valve all is equipped with corresponding valve, the inside of second separation chamber is provided with second filtration membrane, second filtration membrane is the tilt state, second filtration membrane's aperture ratio first filtration membrane is little.
Further, the second separation chamber is externally close to the high-end side of the second filtering membrane inclination is provided with a second liquid storage box, the second liquid storage box is close to one side of the second separation chamber is provided with a second liquid conveying device, the liquid suction end of the second liquid conveying device is communicated with the second liquid storage box, the liquid outlet end of the second liquid conveying device is communicated with a second liquid conveying pipe, the second liquid conveying pipe is communicated with the second separation chamber, and the communication port is located at the high-end upper side of the second filtering membrane inclination.
Furthermore, a second collecting box is arranged on one side, close to the inclined lower end of the second filtering membrane, of the outside of the second separation cavity, a second pipeline is communicated with the upper end of the second collecting box, the other end of the second pipeline is communicated with the second separation cavity, and a communication port is located on one side of the lower end of the second filtering membrane.
Furthermore, a liquid outlet pipe is arranged at the bottom of the second separation cavity, a valve is mounted on the liquid outlet pipe, the lower end of the liquid outlet pipe is communicated with a liquid collecting box, a vacuum pump is arranged on one side of the liquid collecting box, the air suction end of the vacuum pump is communicated with an air suction pipe, and the air suction pipe is communicated with one side of the liquid collecting box.
Further, the upper end threaded connection of injector has sealed lid, sealed lid with injector inlet end connection department is provided with the sealing ring, the intercommunication has the inlet pipe in the middle of the sealed lid, the inlet pipe with sealed lid connection department also is equipped with the sealing ring, the inlet pipe with the injector top is linked together, install the electrovalve door on the inlet pipe.
The utility model discloses an improve and provide a separator of extracellular vesicle here, compare with prior art, have following improvement and advantage:
the utility model discloses a connect the inlet pipe sample outlet of sample collection device, open the electrovalve, make the sample get into the sample injector inside, avoid the dust to get into the sample injector inside and cause the pollution, thereby influence the separation, through microfiltration membrane filtration detach blood platelet and cell debris that probably contains in the body fluid, through the double filtration of first filtration membrane and second filtration membrane, the aperture of first filtration membrane and second filtration membrane is different, in order to respectively carry out intercepting, classification to the extracellular vesicles of different particle diameters, and carry out corresponding analysis, research and application after collecting, through first liquid conveyor and second liquid conveyor carry balanced liquid vesicles to first filtration membrane and second filtration membrane upper end, wash the outer of first filtration membrane and second filtration membrane upper end, through the valve of opening first pipeline and second pipeline, make outer vesicle bubble get into first collecting box and the inside collection that collects of second collecting box, because first filtration membrane and second filtration membrane are the slope form, utilize balanced liquid to be convenient for rush into first collecting box and second collecting box through the first filtration membrane and the second filtration membrane of slope inside, simultaneously with first filtration membrane and second filtration membrane set up to the slope form, prevent to block up, make outer vesicle granule slide to first filtration membrane and second filtration membrane slope low side, flow in the middle of the liquid accessible and the upper end, avoid whole blockings up, first separation chamber and second separation chamber are transparent material, make the user discover this problem in time more easily.
Drawings
The invention is further explained below with reference to the figures and examples:
FIG. 1 is a schematic view of the front view structure of the present invention;
fig. 2 is an enlarged schematic structural view of a point a in fig. 1 according to the present invention;
fig. 3 is an enlarged schematic structural diagram of the position B in fig. 1 of the present invention.
Description of the reference numerals: 1. a sample injector; 2. a microfiltration membrane; 7. a first three-way valve; 8. a liquid feeder; 9. a first separation chamber; 10. a first filter membrane; 11. a first infusion tube; 12. a second infusion tube; 13. a first liquid delivery device; 14. a first liquid storage tank; 15. a first conduit; 16. a second liquid delivery device; 17. a first collection tank; 18. a second three-way valve; 19. a second separation chamber; 20. a second filter membrane; 21. a second liquid storage tank; 22. a second collection tank; 23. a liquid outlet pipe; 24. a liquid collection tank; 25. a vacuum pump; 26. a second conduit; 27. a sealing cover; 28. a seal ring; 29. a feeding pipe; 30. an electric valve; 31. and (4) sucking a pipe.
Detailed Description
The present invention will be described in detail with reference to the accompanying drawings 1 to 3, which clearly and completely describe the technical solutions in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.
The utility model provides a separation device of extracellular vesicles through improvement, as shown in figures 1-3, comprising a sample injector 1, a microfiltration membrane 2 is arranged at the lower end of the interior of the sample injector 1, the bottom end of the interior of the sample injector 1 is arc-shaped, a first three-way valve 7 is arranged at the bottom of the sample injector 1, the upper end of the first three-way valve 7 is detachably connected with the bottom of the sample injector 1 through a luer connector, a first separation cavity 9 is arranged at the lower end of the first three-way valve 7, the first separation cavity 9 is made of transparent material, the lower ends of the first separation cavity 9 and the first three-way valve 7 are detachably connected through a luer connector, a liquid injector 8 is arranged in the middle of the first three-way valve 7, the liquid injector 8 and the middle of the first three-way valve 7 are detachably connected through a luer connector, corresponding valves are arranged at the three ends of the first three-way valve 7, a first filtering membrane 10 is arranged in the interior of the first separation cavity 9, the first filtering membrane 10 is in an inclined state, a first liquid storage box 14 is arranged on one side of the outside of the first separation cavity 9, which is close to the inclined high end of the first filtering membrane 10, a first liquid conveying device 13 is arranged on one side of the first liquid storage box 14, which is close to the first separation cavity 9, the liquid suction end of the first liquid conveying device 13 is communicated with the first liquid storage box 14, the liquid outlet end of the first liquid conveying device 13 is communicated with a first liquid conveying pipe 11, the first liquid conveying pipe 11 is communicated with the first separation cavity 9, and the communication port is arranged at the upper end of the inclined high position of the first filtering membrane 10, liquid to be filtered, such as peripheral blood, urine, saliva, cerebrospinal fluid, milk, ascites, amniotic fluid and the like, enters the sample injector 1, platelets and cell debris and the like possibly contained in the body fluid are filtered and removed through the microfiltration membrane 2, the upper and lower valves of the first three-way valve 7 are opened, so that the sample enters the first separation cavity 9 to be filtered and separated through the first filtering membrane 10, first filtration membrane 10 is the slope state, make outer vesicle most remain in first filtration membrane 10 slope low side, other positions that liquid can also follow first filtration membrane 10 filter, first separation chamber 9 is transparent material, be convenient for observe the inside separation condition, when will drawing the outer vesicle on first filtration membrane 10, start first liquid conveyor 13, open the valve on first transfer line 11, first liquid conveyor 13 deposits the balanced liquid of case 14 with first liquid and carries to the inside first filtration membrane 10 of first separation chamber 9, wash first filtration membrane 10 and make outer vesicle towards the first filtration membrane 10 low side department.
The bottom of the first separation cavity 9 is provided with a second three-way valve 18, the upper end of the second three-way valve 18 is detachably connected with the bottom of the first separation cavity 9 through a luer connector, the lower end of the second three-way valve 18 is provided with a second separation cavity 19, the second separation cavity 19 is made of transparent materials, the lower ends of the second separation cavity 19 and the second three-way valve 18 are detachably connected through a luer connector, a liquid charger 8 is arranged in the middle of the second three-way valve 18, the liquid charger 8 and the second three-way valve 18 are detachably connected through a luer connector, three ends of the second three-way valve 18 are respectively provided with corresponding valves, a second filtering membrane 20 is arranged in the second separation cavity 19, the second filtering membrane 20 is in an inclined state, the aperture of the second filtering membrane 20 is smaller than that of the first filtering membrane 10, when balance liquid is put into the first separation cavity 9, the upper end valve of the second three-way valve 18 is closed, the liquid in the first separation cavity 9 does not enter the second separation cavity 19, when the three-way valve is required to discharge liquid, the upper end valve of the second filtering membrane 18 is opened, the aperture of the second filtering membrane 20 is smaller than the first filtering membrane 10, so that extracellular vesicles with different particle sizes can be respectively intercepted, and correspondingly collected, classified, and analyzed and correspondingly analyzed and analyzed after the liquid is discharged.
The second liquid storage box 21 is arranged on one side, close to the inclined high end of the second filtering membrane 20, of the outside of the second separation cavity 19, the second liquid storage box 21 is provided with a second liquid conveying device 16 on one side, close to the second separation cavity 19, of the second liquid conveying device 16, the liquid suction end of the second liquid conveying device 16 is communicated with the second liquid storage box 21, the liquid outlet end of the second liquid conveying device 16 is communicated with the second liquid conveying pipe 12, the second liquid conveying pipe 12 is communicated with the second separation cavity 19, the communication port is located on the inclined high end upper side of the second filtering membrane 20, the second filtering membrane 20 is in an inclined shape, when the outer vesicle at the upper end of the second filtering membrane 20 needs to be extracted, a valve on the second liquid conveying pipe 12 is opened, the second liquid conveying device 16 is started, balance liquid inside the second liquid storage box 21 enters the upper end of the second filtering membrane 20 inside the second separation cavity 19, the outer vesicle of the second filtering membrane 20 is washed, and the outer vesicle at the lower end of the upper end of the second filtering membrane 20 is flushed towards the inclined low end of the second filtering membrane 20.
The outside of second separation chamber 19 is close to second filtration membrane 20 slope low end one side and is provided with second collecting box 22, the upper end intercommunication of second collecting box 22 has second pipeline 26, the other end and the second separation chamber 19 of second pipeline 26 are linked together, and the intercommunication mouth is located second filtration membrane 20 low end one side, open the valve of second pipeline 26, wash through balanced liquid, make outer vesicle bubble get into inside second collecting box 22 through second pipeline 26, when the height of the inside balanced liquid of second separation chamber 19 surpassed second filtration membrane 20, outer vesicle bubble of balanced liquid upper end also can get into inside second collecting box 22 through second pipeline 26, because second filtration membrane 20 is the tilt state, direction is led to outer vesicle bubble rush current direction, outer vesicle bubble gets into inside second collecting box 22 when more convenient.
A liquid outlet pipe 23 is arranged at the bottom of the second separation cavity 19, a valve is mounted on the liquid outlet pipe 23, the lower end of the liquid outlet pipe 23 is communicated with a liquid collection box 24, a vacuum pump 25 is arranged on one side of the liquid collection box 24, the air suction end of the vacuum pump 25 is communicated with an air suction pipe 31, the air suction pipe 31 is communicated with one side of the liquid collection box 24, and the vacuum pump 25 is used for sucking gas of the liquid collection box 24 to enable the liquid collection box 24 to be at negative pressure so as to facilitate downward circulation of liquid.
The upper end threaded connection of injector 1 has sealed lid 27, sealed lid 27 and injector 1 entrance point junction are provided with sealing ring 28, the intercommunication has inlet pipe 29 in the middle of the sealed lid 27, inlet pipe 29 and sealed lid 27 junction also are equipped with sealing ring 28, inlet pipe 29 and injector 1 top are linked together, install electric valve 30 on the inlet pipe 29, through the appearance mouth of connecting inlet pipe 29 with sample collection device, open electric valve 30, make the sample get into inside the injector 1, avoid the dust to get into the inside pollution that causes of injector 1, thereby influence the separation.
The working principle is as follows: firstly, the feeding pipe 29 is connected with a sample outlet of the sample collecting device, the electric valve 30 is opened, so that a sample enters the sample injector 1, the dust is prevented from entering the sample injector 1 to cause pollution, the separation is influenced, the vacuum pump 25 is opened, the vacuum pump 25 is used for pumping the gas of the liquid collecting box 24 to ensure that the liquid collecting box 24 is at negative pressure, the liquid is convenient to flow downwards, the liquid to be filtered enters the sample injector 1, the micro-filtration membrane 2 is used for filtering and removing blood platelets and cell debris and the like possibly contained in body fluid, the upper valve and the lower valve of the first three-way valve 7 are opened, so that the sample enters the first separation cavity 9 to be filtered and separated through the first filtration membrane 10, the first filtration membrane 10 is in an inclined state, most of outer cysts are left on the inclined lower end side of the first filtration membrane 10, the liquid can be filtered from other positions of the first filtration membrane 10, and the first separation cavity 9 is made of transparent material, when the outer vesicles on the first filter membrane 10 are to be extracted, the upper end valve of the second three-way valve 18 is closed to prevent the liquid in the first separation chamber 9 from entering the second separation chamber 19, the first liquid conveying device 13 is started to open the valve on the first infusion tube 11, the first liquid conveying device 13 conveys the balance liquid in the first liquid storage tank 14 to the first filter membrane 10 in the first separation chamber 9, the first filter membrane 10 is flushed to flush the outer vesicles towards the lower end of the first filter membrane 10, when the balance liquid is discharged, the valve of the first pipeline 15 is opened to allow the outer vesicles to enter the first collection box 17 through the first pipeline 15 for collection, and when the height of the balance liquid is higher than that of the first filter membrane 10 in the first separation chamber 9, the outer vesicles at the upper end of the balance liquid can also enter the first collection box 17 through the first pipeline 15, avoid dismantling, the aperture ratio of second filtration membrane 20 is little than first filtration membrane 10, in order to respectively carry out the intercepting to the outer vesicle bubble of different particle diameters, classify, and carry out corresponding analysis after collecting, research and application, when needing to draw the outer vesicle on second filtration membrane 20, close the valve on drain pipe 23, open the valve on second transfer line 12, start second liquid conveyor 16, make the inside balanced liquid of second liquid storage box 21 get into the inside second filtration membrane 20 upper end of second separation chamber 19, wash the outer vesicle bubble of second filtration membrane 20 upper end, make outer vesicle bubble towards the first department low end of second filtration membrane 20 slope, open the valve of second pipeline 26, wash through balanced liquid, make outer vesicle bubble get into inside second collecting box 22 through second pipeline 26, when the height of the inside balanced liquid of second separation chamber 19 surpassed second filtration membrane 20, the outer vesicle bubble of balanced liquid upper end also can get into inside second collecting box 22 through second pipeline 26.
The previous description of the disclosed embodiments is provided to enable any person skilled in the art to make or use the present invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the generic principles defined herein may be applied to other embodiments without departing from the spirit or scope of the invention. Thus, the present invention is not intended to be limited to the embodiments shown herein but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.
Claims (7)
1. An apparatus for separating extracellular vesicles, comprising: comprises a sample injector (1), the inside lower extreme of sample injector (1) is provided with microfiltration membrane (2), the inside bottom of sample injector (1) is the arc, sample injector (1) bottom is provided with first three-way valve (7), the upper end of first three-way valve (7) with the bottom of sample injector (1) can dismantle the connection through luer connector, the lower extreme of first three-way valve (7) is provided with first disengagement chamber (9), first disengagement chamber (9) is transparent material, first disengagement chamber (9) with the lower extreme of first three-way valve (7) can dismantle the connection through luer connector, the centre of first three-way valve (7) is provided with liquid filler (8), liquid filler (8) with the centre of first three-way valve (7) can dismantle the connection through luer connector, first disengagement chamber (7) three-end all is equipped with corresponding valve, the inside of first disengagement chamber (9) is provided with first filtration membrane (10), first filtration membrane (10) is the tilt state, first disengagement chamber (9) is close to first filtration membrane (10) the outside deposit first filtration membrane (10) slope deposit case (10) one side and deposit case (14) and carry first liquid delivery device (13) and first liquid delivery case (14) is provided with liquid delivery device (13), the liquid outlet end of the first liquid conveying device (13) is communicated with a first liquid conveying pipe (11), the first liquid conveying pipe (11) is communicated with the first separation cavity (9), and a communication opening is formed in the upper end of the inclined high position of the first filtering membrane (10).
2. The apparatus for separating extracellular vesicles according to claim 1, wherein: the first separation cavity (9) is externally provided with a first collecting box (17) at one side of the inclined lower end of the first filtering membrane (10), the upper end of the first collecting box (17) is communicated with a first pipeline (15), the other end of the first pipeline (15) is communicated with the first separation cavity (9), a communicating port is formed in the upper side of the inclined lower end of the first filtering membrane (10), and valves are arranged on the first pipeline (15) and the first infusion tube (11).
3. The apparatus for separating extracellular vesicles according to claim 2, wherein: the bottom of first separation chamber (9) is provided with second three-way valve (18), the upper end of second three-way valve (18) with the bottom of first separation chamber (9) is passed through luer and is connect can dismantle the connection, the lower extreme of second three-way valve (18) is provided with second separation chamber (19), second separation chamber (19) are transparent material, second separation chamber (19) with the lower extreme of second three-way valve (18) is passed through luer and is connect can dismantle the connection, be provided with liquid filler (8) in the middle of second three-way valve (18), liquid filler (8) with the connection can be dismantled through luer in the middle of second three-way valve (18), the three-terminal of second three-way valve (18) all is equipped with corresponding valve, the inside of second separation chamber (19) is provided with second filtration membrane (20), second filtration membrane (20) are the slope state, the aperture ratio of second filtration membrane (20) first filtration membrane (10) are little.
4. The apparatus for separating extracellular vesicles according to claim 3, wherein: second separation chamber (19) outside is close to the high-end one side of second filtration membrane (20) slope is provided with second liquid and deposits case (21), second liquid is deposited case (21) and is close to one side of second separation chamber (19) is provided with second liquid conveyor (16), the imbibition end of second liquid conveyor (16) with second liquid is deposited case (21) and is linked together, the play liquid end intercommunication of second liquid conveyor (16) has second transfer line (12), second transfer line (12) with second separation chamber (19) are linked together, and the intercommunication mouth is located the high-end upside of second filtration membrane (20) slope.
5. The apparatus for separating extracellular vesicles according to claim 4, wherein: a second collecting box (22) is arranged on one side, close to the inclined lower end of the second filtering membrane (20), of the outer portion of the second separation cavity (19), a second pipeline (26) is communicated with the upper end of the second collecting box (22), the other end of the second pipeline (26) is communicated with the second separation cavity (19), and a communication port is located on one side of the lower end of the second filtering membrane (20).
6. The apparatus for separating extracellular vesicles according to claim 5, wherein: the liquid collecting device is characterized in that a liquid outlet pipe (23) is arranged at the bottom of the second separation cavity (19), a valve is mounted on the liquid outlet pipe (23), a liquid collecting box (24) is communicated with the lower end of the liquid outlet pipe (23), a vacuum pump (25) is arranged on one side of the liquid collecting box (24), an air suction end of the vacuum pump (25) is communicated with an air suction pipe (31), and the air suction pipe (31) is communicated with one side of the liquid collecting box (24).
7. The apparatus for separating extracellular vesicles according to claim 1, wherein: the upper end threaded connection of application of sample ware (1) has sealed lid (27), sealed lid (27) with application of sample ware (1) entrance point junction is provided with sealing ring (28), the intercommunication has inlet pipe (29) in the middle of sealed lid (27), inlet pipe (29) with sealed lid (27) junction also is equipped with sealing ring (28), inlet pipe (29) with application of sample ware (1) top is linked together, install electric valve (30) on inlet pipe (29).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202221928241.9U CN217973184U (en) | 2022-07-26 | 2022-07-26 | Separation device for extracellular vesicles |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202221928241.9U CN217973184U (en) | 2022-07-26 | 2022-07-26 | Separation device for extracellular vesicles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN217973184U true CN217973184U (en) | 2022-12-06 |
Family
ID=84281925
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202221928241.9U Active CN217973184U (en) | 2022-07-26 | 2022-07-26 | Separation device for extracellular vesicles |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN217973184U (en) |
-
2022
- 2022-07-26 CN CN202221928241.9U patent/CN217973184U/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN108652517B (en) | Handheld dust catcher and prefilter subassembly | |
| CN108652518B (en) | Hand-held dust collector | |
| CN206285053U (en) | A kind of dust exhaust apparatus | |
| CN108606716B (en) | Handheld dust collector and air treatment assembly | |
| CN217973184U (en) | Separation device for extracellular vesicles | |
| CN2530580Y (en) | Dust-separating mechanism for cyclone suction cleaner | |
| CN109317389B (en) | Synchronous separator of many particle diameters microplastic in stirring formula deposit or earth | |
| CN109621512A (en) | It is a kind of can automatic sampling improvement Suction filtration device and filter method | |
| CN212008554U (en) | Water quality on-line monitoring preprocessing device | |
| CN210786415U (en) | Bag type sewage treatment system | |
| CN210124713U (en) | Dust deposition base and cleaning equipment assembly with same | |
| CN209361958U (en) | It is a kind of can automatic sampling improvement Suction filtration device | |
| CN209372488U (en) | A kind of Research of Environmental Sciences's sewage collector | |
| CN201064421Y (en) | Dust cleaning barrel | |
| CN219517961U (en) | Reagent filter equipment | |
| CN220663584U (en) | Liquid alkali storage tank | |
| CN211079161U (en) | Separation and purification device | |
| CN210495412U (en) | Feather protein deposits filter equipment | |
| CN213537491U (en) | Industrial sludge collecting device | |
| CN211737396U (en) | Vacuum device for automatically separating gas and liquid impurities | |
| CN220432397U (en) | Waste liquid discharging structure of suction filtration bottle | |
| CN220484061U (en) | Sampling storage device for water quality detection | |
| CN214021606U (en) | Anti-clogging device for hair washing of semi-automatic bottle washing machine | |
| CN213408254U (en) | Hollow fiber ultrafiltration system | |
| CN218421272U (en) | Ultrafiltration device for water purification treatment |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant |