CN217962604U - Constant temperature water bath device for serum protein purification treatment - Google Patents
Constant temperature water bath device for serum protein purification treatment Download PDFInfo
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- CN217962604U CN217962604U CN202221952394.7U CN202221952394U CN217962604U CN 217962604 U CN217962604 U CN 217962604U CN 202221952394 U CN202221952394 U CN 202221952394U CN 217962604 U CN217962604 U CN 217962604U
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- water bath
- serum protein
- fixedly connected
- limiting
- purifying
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- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 title claims abstract description 69
- 102000004506 Blood Proteins Human genes 0.000 title claims abstract description 41
- 108010017384 Blood Proteins Proteins 0.000 title claims abstract description 41
- 238000001742 protein purification Methods 0.000 title claims abstract description 11
- 230000007246 mechanism Effects 0.000 claims abstract description 23
- 238000007789 sealing Methods 0.000 claims description 24
- 230000005389 magnetism Effects 0.000 claims description 6
- 238000004321 preservation Methods 0.000 claims description 2
- 239000012153 distilled water Substances 0.000 abstract description 17
- 230000000630 rising effect Effects 0.000 abstract description 5
- 210000002966 serum Anatomy 0.000 description 14
- 238000000746 purification Methods 0.000 description 10
- 238000000034 method Methods 0.000 description 7
- 230000000694 effects Effects 0.000 description 6
- 102000007562 Serum Albumin Human genes 0.000 description 5
- 108010071390 Serum Albumin Proteins 0.000 description 5
- 230000008859 change Effects 0.000 description 5
- 238000001816 cooling Methods 0.000 description 4
- 230000008569 process Effects 0.000 description 4
- 238000000926 separation method Methods 0.000 description 4
- 230000009471 action Effects 0.000 description 3
- 102000009027 Albumins Human genes 0.000 description 2
- 108010088751 Albumins Proteins 0.000 description 2
- 102000001554 Hemoglobins Human genes 0.000 description 2
- 108010054147 Hemoglobins Proteins 0.000 description 2
- 108010062374 Myoglobin Proteins 0.000 description 2
- 102000036675 Myoglobin Human genes 0.000 description 2
- 238000010438 heat treatment Methods 0.000 description 2
- 230000002159 abnormal effect Effects 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 238000009413 insulation Methods 0.000 description 1
- 210000001503 joint Anatomy 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 238000002636 symptomatic treatment Methods 0.000 description 1
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Abstract
The utility model discloses a thermostatic waterbath device for purifying serum protein, which relates to the technical field of serum protein purification treatment and comprises a water bath box, wherein a leak hole supporting plate is movably arranged in the water bath box, a cold and hot pipe is arranged at the bottom of the water bath box, and a drain pipe which is communicated outwards is fixedly connected at the bottom of the rear side of the water bath box; the inside both sides fixedly connected with stop gear of water bath, the both sides of small opening backup pad are equipped with the latch mechanism with stop gear assorted. This constant temperature water bath device is used in serum protein purification treatment, the both sides of small opening backup pad are equipped with the latch mechanism with stop gear assorted, and the small opening backup pad passes through latch mechanism to be installed at stop gear's not co-altitude. Therefore, the level of the leak hole supporting plate can be adjusted according to the height of the serum protein container, so that the level of the serum protein in the serum protein container and the height of the distilled water are lower than each other or are lower than each other, and the temperature rising or reducing speed of the serum protein in the container is further improved.
Description
Technical Field
The utility model relates to a serum protein purification treatment technical field specifically is a serum protein purification treatment is with water bath with thermostatic control device.
Background
The serum protein measurement and examination can judge the abnormal physical condition of the examinee according to the body nutrition state and immune state level of the examinee, thereby facilitating the symptomatic treatment of the examinee. And present serum albumen is when separation purification handles, need use the thermostatic waterbath device to carry out purification treatment to serum albumen, can improve serum albumen's purification treatment efficiency, but owing to the serum albumen volume that will purify the treatment differs, the container size of storage serum albumen highly differs, because the inside fagging of thermostatic waterbath device highly can't be adjusted, the horizontal plane that leads to serum albumen in the container of part height is higher than the horizontal plane in the thermostatic waterbath device, it is relatively poor to lead to the serum albumen constant temperature treatment effect that exceeds, influence serum albumen's purification treatment.
Therefore, it is necessary to provide a thermostatic waterbath device for serum protein purification treatment to solve the above problems.
SUMMERY OF THE UTILITY MODEL
An object of the utility model is to provide a serum albumen purification is handled and is used water bath with constant temperature device to in solving the current water bath with constant temperature device that proposes among the above-mentioned background art to serum albumen purification, can't be according to the height of the inside fagging of serum albumen container altitude mixture control, serum albumen constant temperature treatment effect relatively poor problem in the container that leads to the part height.
In order to achieve the above purpose, the utility model discloses a following technical scheme realizes: a constant temperature water bath device for purifying and treating serum protein comprises a water bath tank, wherein a leak hole supporting plate is movably arranged in the water bath tank, a cold and hot pipe is arranged at the bottom of the water bath tank, and the bottom of the rear side of the water bath tank is fixedly connected with a drain pipe which is communicated outwards;
the two sides in the water bath box are fixedly connected with limiting mechanisms, the two sides of the leak hole supporting plate are provided with clamping mechanisms matched with the limiting mechanisms, and the leak hole supporting plate is arranged at different heights of the limiting mechanisms through the clamping mechanisms;
the limiting mechanism comprises a limiting plate, a limiting groove is formed in the middle of the limiting plate, a magnet piece is fixedly connected to the inner side of the limiting groove, and a plurality of groups of rotating grooves A are formed in two sides of the limiting groove;
clamping mechanism is including rotating groove B and rotating the post, it rotates the inside that sets up at rotating groove B to rotate the post, the top fixedly connected with of rotating the post changes the board with the rotation groove A assorted magnetism and changes the board, magnetism changes the board and changes the contained angle between the board and be ninety degrees.
Optionally, the top of the inner side of the water bath box is fixedly connected with a ring plate for supporting the heat preservation cover.
Optionally, a sealing cover is hermetically mounted at the top of the water bath box.
Optionally, a sealing groove is formed in the top of the water bath box, and a sealing strip is fixedly connected to the bottom of the sealing cover and the corresponding position of the sealing groove.
Optionally, a plurality of placing grooves are formed in the top of the leak hole supporting plate.
Optionally, a plurality of the placing grooves are distributed at equal intervals.
Optionally, the plurality of groups of rotating grooves a are arranged at equal intervals.
Compared with the prior art, the utility model provides a serum protein purification is with thermostatic waterbath device possesses following beneficial effect:
1. this serum protein purification is with thermostatic waterbath device, the inside both sides fixedly connected with stop gear of water bath case, the both sides of small opening backup pad be equipped with stop gear assorted latch mechanism, the small opening backup pad passes through latch mechanism and installs the not co-altitude at stop gear. Therefore, the horizontal height of the leak hole supporting plate can be adjusted according to the height of the serum protein container, so that the horizontal plane of the serum protein in the serum protein container and the height level of the distilled water or the height lower than the height of the distilled water are ensured, the temperature rising or cooling speed of the serum protein in the container is further improved, and the using effect is better.
2. This serum protein purification is with thermostatic waterbath device, the sealed lid of top seal installation of water bath, the seal groove has been seted up at the top of water bath, and the bottom of sealed lid corresponds position fixedly connected with sealing strip with the seal groove. The temperature rising or lowering speed of the distilled water is further improved through the sealing cover, the temperature generally required for the separation and purification of the hemoglobin, the myoglobin and the albumin is about 25 ℃, and the distilled water in the water bath box can reach the temperature more quickly through the arrangement of the sealing cover. Through the setting of sealed lid, make the device suitability stronger, the range of application is wider.
Drawings
FIG. 1 is a schematic view of a cold-hot tube structure of a constant temperature water bath device for purifying serum proteins according to the present invention;
FIG. 2 is a schematic view of a leak hole supporting plate structure of the constant temperature water bath device for purifying serum proteins of the present invention;
FIG. 3 is an enlarged schematic view of the structure of the region A in FIG. 2 of the constant temperature water bath apparatus for purifying and treating serum proteins of the present invention;
FIG. 4 is a schematic view of the ring plate structure of the thermostatic waterbath device for purifying serum proteins of the present invention;
FIG. 5 is a schematic view of the sealing cover mounting structure of the thermostatic waterbath device for purifying serum proteins of the present invention;
FIG. 6 is a schematic diagram of the sealing cover structure of the thermostatic water bath device for purifying and treating serum protein.
In the figure: 1. a water bath tank; 2. a leak hole supporting plate; 3. a cold and hot pipe; 4. a drain pipe; 5. a limiting plate; 6. a limiting groove; 7. a magnet piece; 8. a rotating groove A; 9. a rotating groove B; 10. rotating the column; 11. a magnetic rotating plate; 12. rotating the plate; 13. a ring plate; 14. a placement groove; 15. a sealing groove; 16. a sealing cover; 17. a sealing strip.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative efforts all belong to the protection scope of the present invention.
In the description of the present invention, it is to be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "connected," and "connected" are to be construed broadly, and may be, for example, fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meaning of the above terms in the present invention can be understood in specific cases to those skilled in the art.
The technical features mentioned in the different embodiments of the invention described below can be combined with each other as long as they do not conflict with each other.
Referring to fig. 1-3, an embodiment of the present application provides a thermostatic waterbath apparatus for purifying serum protein, which includes a water bath tank 1, a leak hole supporting plate 2 movably installed inside the water bath tank 1, a cold and hot pipe 3 installed at the bottom of the water bath tank 1, and a drain pipe 4 fixedly connected to the bottom of the rear side of the water bath tank 1 and penetrating outward.
In this embodiment, after the distilled water is poured into the water bath 1, the container of serum protein is supported by the perforated support plate 2, and the water is heated or cooled by the cold and hot pipe 3, so that the water bath 1 keeps a better dissolving temperature, thereby improving the separation and purification effect of serum protein.
In this embodiment, in addition, the inside both sides fixedly connected with stop gear of water bath 1, the both sides of small opening backup pad 2 be equipped with stop gear assorted latch mechanism, small opening backup pad 2 passes through latch mechanism and installs the not co-altitude at stop gear. The level of the leak hole supporting plate 2 can be adjusted according to the height of the container of the serum albumin, so that the level of the serum albumin in the container of the serum albumin and the height of the distilled water or the height of the serum albumin lower than the height of the distilled water are increased, the temperature rising or cooling speed of the serum albumin in the container is increased, and the using effect is better.
The limiting mechanism comprises a limiting plate 5, a limiting groove 6 is formed in the middle of the limiting plate 5, a magnet piece 7 is fixedly connected to the inner side of the limiting groove 6, and a plurality of groups of rotating grooves A8 are formed in two sides of the limiting groove 6; the clamping mechanism comprises a rotating groove B9 and a rotating column 10, the rotating column 10 is rotatably arranged inside the rotating groove B9, the top of the rotating column 10 is fixedly connected with a magnetic rotating plate 11 and a rotating plate 12 which are matched with the rotating groove A8, and an included angle between the magnetic rotating plate 11 and the rotating plate 12 is ninety degrees. The plurality of groups of rotating grooves A8 are arranged at equal intervals.
In this embodiment, change board 11 and change board 12 through magnetism and can conveniently rotate the rotation of post 10, change the butt joint of board 11 through magnet piece 7 and magnetism simultaneously and can fix the 2 level in small opening backup pad with magnetic force, change 12 non-magnetic forces on the board, can be when adjusting the 2 level in small opening backup pad, will change board 12 and rotate and move into spacing groove 6 and adjust.
Referring to fig. 3-6, in an embodiment of the present application, a ring plate 13 is fixedly connected to the top of the inner side of the water bath tank 1 for supporting the heat insulation cover, so that the distilled water is heated or cooled more quickly, and the temperature maintaining effect is better.
Further, a sealing cover 16 is hermetically mounted at the top of the water bath tank 1, a sealing groove 15 is formed in the top of the water bath tank 1, and a sealing strip 17 is fixedly connected to the bottom of the sealing cover 16 and the sealing groove 15 at a position corresponding to each other. The temperature rising or lowering speed of the distilled water is further increased by the sealing cover 16, the temperature generally required for the separation and purification of hemoglobin, myoglobin and albumin is about 25 ℃, and the distilled water in the water bath tank 1 can reach the temperature more quickly by the arrangement of the sealing cover 16. Through the setting of sealed lid 16, make the device suitability stronger, the range of application is wider.
In this embodiment, in addition, a plurality of standing grooves 14 have been seted up at the top of small opening backup pad 2, and a plurality of standing grooves 14 are equidistant distribution, can carry out the constant temperature water bath to many examples serum albumen respectively through a plurality of standing grooves 14 to improve the purification efficiency to serum albumen.
The utility model discloses when using:
firstly, the horizontal height of the leak hole supporting plate 2 is adjusted according to the serum protein container to be purified, during adjustment, the rotating column 10 is rotated through the two groups of magnetic rotating plates 11 and 12, when the proper height is adjusted, the two groups of magnetic rotating plates 11 and the magnetic rotating plates 11 of the rotating plates 12 are rotated into the limiting groove 6, and the two ends of the leak hole supporting plate 2 are kept stable through the magnetic adsorption of the magnetic rotating plates 11 and the magnet sheets 7.
Then, distilled water is poured into the water bath tank 1, the distilled water is required to reach or exceed the level of serum protein in the protein container, then the distilled water is heated or cooled through the cold-hot pipe 3, and in the heating and cooling process, the top of the water bath tank 1 can be sealed through the sealing cover 16, so that the heating or cooling speed of the distilled water is increased.
Finally, after the distilled water is kept at a predetermined temperature, the sealing cap 16 is removed, and the serum protein is purified by placing a serum protein container in the distilled water kept at a constant temperature in the holding tank 14.
It should be noted that, in this document, relational terms such as first and second, and the like are used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus. Without further limitation, an element defined by the phrases "comprising one of 8230; \8230;" 8230; "does not exclude the presence of additional like elements in a process, method, article, or apparatus that comprises the element.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (7)
1. The utility model provides a serum protein purification is with thermostatic waterbath device, includes water bath (1), its characterized in that: a leak hole supporting plate (2) is movably arranged in the water bath tank (1), a cold and hot pipe (3) is arranged at the bottom of the water bath tank (1), and a drain pipe (4) which is communicated outwards is fixedly connected to the bottom of the rear side of the water bath tank (1);
the two sides in the water bath tank (1) are fixedly connected with limiting mechanisms, the two sides of the leak hole supporting plate (2) are provided with clamping mechanisms matched with the limiting mechanisms, and the leak hole supporting plate (2) is arranged at different heights of the limiting mechanisms through the clamping mechanisms;
the limiting mechanism comprises a limiting plate (5), a limiting groove (6) is formed in the middle of the limiting plate (5), magnet pieces (7) are fixedly connected to the inner side of the limiting groove (6), and a plurality of groups of rotating grooves A (8) are formed in two sides of the limiting groove (6);
clamping mechanism is including rotating groove B (9) and rotating post (10), it rotates the inside that sets up at rotating groove B (9) to rotate post (10), the top fixedly connected with who rotates post (10) changes board (11) and commentaries on classics board (12) with the magnetism that rotates groove A (8) assorted, magnetism changes board (11) and changes the contained angle between board (12) for ninety degrees.
2. The thermostatic waterbath device for purifying and processing serum protein according to claim 1, characterized in that: the top of the inner side of the water bath box (1) is fixedly connected with a ring plate (13) for supporting a heat preservation cover.
3. The thermostatic waterbath device for purifying and treating serum protein according to claim 2, characterized in that: the top of the water bath box (1) is hermetically provided with a sealing cover (16).
4. The thermostatic waterbath device for purifying and treating serum protein according to claim 3, characterized in that: seal groove (15) have been seted up at the top of water bath (1), the bottom of sealed lid (16) corresponds position fixedly connected with sealing strip (17) with seal groove (15).
5. The thermostatic waterbath device for purifying and treating serum protein according to claim 4, characterized in that: the top of the leak hole supporting plate (2) is provided with a plurality of placing grooves (14).
6. The thermostatic waterbath device for purifying and processing serum protein according to claim 5, characterized in that: the placing grooves (14) are distributed at equal intervals.
7. The thermostatic waterbath device for purifying and treating serum protein according to claim 6, characterized in that: the plurality of groups of the rotating grooves A (8) are arranged at equal intervals.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202221952394.7U CN217962604U (en) | 2022-07-27 | 2022-07-27 | Constant temperature water bath device for serum protein purification treatment |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202221952394.7U CN217962604U (en) | 2022-07-27 | 2022-07-27 | Constant temperature water bath device for serum protein purification treatment |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN217962604U true CN217962604U (en) | 2022-12-06 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202221952394.7U Active CN217962604U (en) | 2022-07-27 | 2022-07-27 | Constant temperature water bath device for serum protein purification treatment |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN217962604U (en) |
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2022
- 2022-07-27 CN CN202221952394.7U patent/CN217962604U/en active Active
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Effective date of registration: 20230425 Address after: 471600 group 13, Yuquan village, Liuquan Town, Yiyang County, Luoyang City, Henan Province Patentee after: Xu Yihui Address before: No. 1103-1, 11th Floor, Building 6, No. 78 Chaofeng Road, Zhengzhou District (Economic Development Zone), Free Trade Zone, Zhengzhou City, Henan Province, 450000 Patentee before: Henan Qianze Biotechnology Co.,Ltd. |