CN217931700U - Luminous immunity analyzer - Google Patents

Luminous immunity analyzer Download PDF

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Publication number
CN217931700U
CN217931700U CN202221291596.1U CN202221291596U CN217931700U CN 217931700 U CN217931700 U CN 217931700U CN 202221291596 U CN202221291596 U CN 202221291596U CN 217931700 U CN217931700 U CN 217931700U
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China
Prior art keywords
injection
quality control
liquid
arm
bottle
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CN202221291596.1U
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Chinese (zh)
Inventor
孟杰
罗伟
章铖皓
童明
战乃乾
吴和晋
蔡坤鹏
余波
胡亚军
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Zhejiang Pushkang Biotechnology Co ltd
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Zhejiang Pushkang Biotechnology Co ltd
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Priority to CN202221291596.1U priority Critical patent/CN217931700U/en
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Abstract

The utility model provides a luminous immunoassay appearance. The analyzer comprises a machine body, a bracket assembly and a liquid injection assembly. The machine body comprises a base; the bracket assembly comprises a tray and a cover plate, wherein the tray is provided with an installation part for installing a detection chip, the cover plate is provided with a covering position for covering the installation part and an avoiding position for avoiding the installation part, and the cover plate is provided with an injection port; the liquid injection component comprises an injection arm, a driving mechanism, an injection rod and a plurality of quality control liquid bottles, the injection arm is movably installed on the base and located above the bracket component, the quality control liquid bottles are installed on the injection arm side by side, the quality control liquid bottles comprise liquid outlets, the driving mechanism is connected with the injection arm in a driving mode, and the injection rod is at least used for applying external force to the quality control liquid bottles so that liquid in the quality control liquid bottles can flow to the injection ports. The utility model discloses can solve the quality control liquid of the luminous immunoassay appearance among the prior art and add mode complex operation's problem.

Description

Luminous immunity analyzer
Technical Field
The utility model relates to the technical field of medical machinery, particularly, relate to a luminous immunoassay appearance.
Background
A luminescence immunoassay analyzer is an analysis instrument that combines a luminescence reaction with an immune reaction to detect an antigen or an antibody. It adopts the micro-multiplication technology, and has good sensitivity and specificity; the detection range is very wide, and the detection range can be detected from traditional proteins, hormones, enzymes to medicines.
At present, when the luminescence immunoassay analyzer is used for detecting and analyzing a sample, different quality control liquids need to be added according to different detection items, the adding mode of the current quality control liquid needs to be manually held and a pipettor is pressed, different quality control bottles need to be replaced according to different detection items, and the luminescence immunoassay analyzer is complex in operation and high in manual labor intensity.
SUMMERY OF THE UTILITY MODEL
A primary object of the present invention is to provide a luminescence immunoassay analyzer to solve the problem of adding complex operation of the quality control liquid of luminescence immunoassay analyzer in the prior art.
In order to achieve the above object, the present invention provides a luminescence immunoassay analyzer, comprising:
a body including a base;
the bracket assembly is arranged on the base and comprises a tray and a cover plate, the tray is rotatably arranged on the base, an installation part for installing a detection chip is arranged on the tray, the cover plate is provided with a covering position for covering the installation part and an avoiding position for avoiding the installation part, and the cover plate is provided with an injection port; and
annotate the liquid subassembly, annotate the liquid subassembly and include application of sample arm, actuating mechanism, notes liquid pole and a plurality of matter accuse liquid bottle, the application of sample arm movably install in the base is located the top of bracket assembly, it is a plurality of matter accuse liquid bottle install side by side in on the application of sample arm, matter accuse liquid bottle includes the liquid outlet, actuating mechanism with application of sample arm drive is connected to make a plurality ofly selectively one in the matter accuse liquid bottle the liquid outlet with the filling port intercommunication, it is right at least to annotate the liquid pole be used for quality accuse liquid bottle exert external force so that the liquid in the matter accuse liquid bottle flows extremely the filling port.
Furthermore, the quality control liquid bottle comprises a bottle body and a spray head, the spray head is arranged on the bottle body, the liquid outlet is arranged on the spray head, and the spray head sprays the liquid in the bottle body out of the liquid outlet under the action of the pressing force exerted by the liquid injection rod;
the sample adding arm is provided with a plurality of positioning holes, the quality control liquid bottles are arranged in the positioning holes in an inverted mode in a one-to-one correspondence mode, and when the driving mechanism drives the sample adding arm to move to a preset position, the liquid outlet of one of the quality control liquid bottles is opposite to the injection port so as to achieve communication.
Furthermore, the sample adding arm can be rotatably or telescopically arranged on the base, and the driving mechanism is in driving connection with the sample adding arm so as to drive the sample adding arm to rotate or stretch.
Furthermore, the sample adding arm is rotatably arranged on the base, and the quality control liquid bottles are arranged on the sample adding arm along the same circumference.
Further, annotate liquid subassembly still includes the substrate and adds the mechanism, the substrate adds the mechanism and includes:
a substrate sample injection needle disposed on the sample injection arm, the substrate sample injection needle being driven by the drive mechanism to communicate with the injection port;
a substrate bottle disposed at the base;
a dosing pump in communication with the substrate bottle and the substrate sample addition needle via a conduit.
Further, a light sealing bin is arranged on the base, and the substrate bottle is arranged in the light sealing bin.
Further, the substrate bottle comprises a bottle body and a bottle cap covering the bottle body, the bottle cap is installed in the light-tight bin through a lifting assembly and connected with the quantitative pump through the pipeline, and the bottle body is replaceably arranged in the light-tight bin.
Furthermore, the injection assembly also comprises a sealing polish rod which is arranged on the sample adding arm in a vertically movable manner and moves to the position above the injection port under the driving of the driving mechanism;
the liquid injection rod is at least used for applying pressing force to the light-tight rod so that the end part of the light-tight rod seals the injection port.
Further, the luminescence immunoassay analyzer further comprises a detection assembly, the detection assembly comprises a PMT module, a lifting mechanism and a light tight ring are arranged on the PMT module, and when the luminescence immunoassay analyzer works, the lifting mechanism is used for driving the light tight ring to abut against the bottom of the tray.
Furthermore, annotate the liquid subassembly still includes the driving piece, the driving piece with annotate liquid pole drive and be connected in order to drive annotate the liquid pole and follow the direction of height up-and-down motion of luminescence immunoassay appearance.
Use the technical scheme of the utility model, the utility model discloses an among the luminescence immunoassay appearance testing process, to the different detection items, only need utilize actuating mechanism drive application of sample arm to remove for the liquid outlet and the filling opening intercommunication of the quality control liquid bottle of corresponding quality control liquid are equipped with, then utilize and annotate the liquid pole and exert external force to the quality control liquid bottle and can be to the corresponding quality control liquid of detection chip filling, whole process can realize unmanned operation, and easy operation can improve the detection efficiency of luminescence immunoassay appearance, and can reduce the detection cost of luminescence immunoassay appearance.
Drawings
The accompanying drawings, which form a part of the specification, are included to provide a further understanding of the invention, and are incorporated in and constitute a part of this specification, illustrate embodiments of the invention and together with the description serve to explain the invention and not to constitute a limitation on the invention. In the drawings:
fig. 1 is a schematic structural diagram of a luminescence immunoassay analyzer disclosed in an embodiment of the present invention at a first viewing angle;
fig. 2 is a schematic structural diagram of a luminescence immunoassay analyzer at a second viewing angle according to an embodiment of the present invention;
fig. 3 is a schematic structural diagram of a luminescence immunoassay analyzer at a third viewing angle according to an embodiment of the present invention;
fig. 4 is a schematic structural diagram of a luminescence immunoassay analyzer disclosed in an embodiment of the present invention at a fourth viewing angle;
fig. 5 is a schematic view of a first structure of a luminescence immunoassay analyzer according to an embodiment of the present invention after a part of a housing is removed;
FIG. 6 is a schematic view of a second embodiment of a luminescence immunoassay analyzer according to the present invention with portions removed;
FIG. 7 is an exploded view of FIG. 6;
fig. 8 is a schematic structural diagram of a liquid injection assembly part disclosed in an embodiment of the present invention;
FIG. 9 is an exploded view of FIG. 8;
figure 10 is a schematic diagram of a substrate bottle portion according to an embodiment of the present invention.
Wherein the figures include the following reference numerals:
10. a body; 11. a base; 12. an upper cover; 20. a bracket assembly; 21. a tray; 211. an installation part; 22. a cover plate; 221. an injection port; 23. a first motor; 24. a second motor; 30. a liquid injection assembly; 31. a sample addition arm; 311. positioning holes; 32. a drive mechanism; 321. a third motor; 322. a first gear; 323. a second gear; 324. a rotating shaft; 325. a chain; 33. a liquid injection rod; 3301. a fourth motor; 3302. a spring; 34. a quality control liquid bottle; 341. a bottle body; 342. a spray head; 3421. a liquid outlet; 35. a substrate addition mechanism; 351. a substrate loading needle; 352. a substrate bottle; 3521. a bottle body; 3522. a bottle cap; 353. a constant delivery pump; 354. a lifting assembly; 36. a dense polish rod; 361. an elastic sealing gasket; 40. a dense light bin; 41. a bin gate; 50. a PMT module; 51. a lifting mechanism; 52. a dense aperture; 60. a display screen; 70. a printer; 80. and a code scanner.
Detailed Description
It should be noted that, in the present invention, the embodiments and features of the embodiments may be combined with each other without conflict. The present invention will be described in detail below with reference to the accompanying drawings in conjunction with embodiments.
It is noted that the terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of exemplary embodiments according to the invention. As used herein, the singular forms "a", "an" and "the" are intended to include the plural forms as well, and it should be understood that when the terms "comprises" and/or "comprising" are used in this specification, they specify the presence of stated features, steps, operations, devices, components, and/or combinations thereof, unless the context clearly indicates otherwise.
Unless specifically stated otherwise, the relative arrangement of the components and steps, the numerical expressions, and numerical values set forth in these embodiments do not limit the scope of the present invention. Meanwhile, it should be understood that the sizes of the respective portions shown in the drawings are not drawn in an actual proportional relationship for the convenience of description. Techniques, methods, and apparatus known to those of ordinary skill in the relevant art may not be discussed in detail but are intended to be part of the specification where appropriate. In all examples shown and discussed herein, any particular value should be construed as merely illustrative, and not limiting. Thus, other examples of the exemplary embodiments may have different values. It should be noted that: like reference numbers and letters refer to like items in the following figures, and thus, once an item is defined in one figure, further discussion thereof is not required in subsequent figures.
Referring to fig. 1 and 2, according to an embodiment of the present invention, a luminescence immunoassay analyzer is provided. Specifically, the luminescence immunoassay analyzer in this embodiment includes a body 10, and this body 10 includes a base 11 and an upper cover 12, and upper cover 12 is set up on base 11 with overturning, when opening upper cover 12, is convenient for control luminescence immunoassay analyzer in order to carry out luminescence immunoassay to samples such as blood. An avoiding space is arranged on the upper cover 12, a display screen 60 is installed in the avoiding space, and the display screen 60 can be used for displaying information such as detection data and detection items of the luminescence immunoassay, and is also convenient for controlling the luminescence immunoassay analyzer. Alternatively, the display screen 60 may be a display screen such as a touch screen.
Further, two opposite sides of the base 11 are provided with a code scanner 80 and a printer 70, wherein the code scanner 80 is used for reading information of a detection chip (not shown in the figure), and after the code scanner 80 reads the information of the detection chip, the information is transmitted to a controller of the luminescence immunoassay analyzer, and the controller can control the luminescence immunoassay analyzer to start a corresponding detection program according to requirements. After the luminescence immunoassay analyzer has finished testing, the test results can be printed out from the printer 70 by selecting them via the display screen 60.
Referring to fig. 3 to 9, the luminescence immunoassay analyzer in the present embodiment further includes a bracket assembly 20 and a liquid injection assembly 30.
The bracket assembly 20 is arranged on the base 11, the bracket assembly 20 comprises a tray 21 and a cover plate 22, the tray 21 is rotatably arranged on the base 11, an installation part 211 for installing a detection chip (not shown in the figure) is arranged on the tray 21, the cover plate 22 is provided with a covering position for covering the installation part 211 and an avoiding position for avoiding the installation part 211, and the cover plate 22 is provided with an injection port 221; the injection component 30 includes an injection arm 31, a driving mechanism 32, an injection rod 33, and a plurality of quality control liquid bottles 34, the injection arm 31 is movably mounted on the base 11 and located above the bracket assembly 20, the plurality of quality control liquid bottles 34 are mounted on the injection arm 31 side by side, the quality control liquid bottles 34 include liquid outlets 3421, the driving mechanism 32 is in driving connection with the injection arm 31 to selectively communicate the liquid outlets 3421 of one of the plurality of quality control liquid bottles 34 with the injection ports 221, and the injection rod 33 is at least used for applying an external force to the quality control liquid bottles 34 to make the liquid in the quality control liquid bottles 34 flow to the injection ports 221.
It will be appreciated that the detection chip described herein is particularly a centrifugal microfluidic chip. In the detection state, the cover plate 22 is in the covering position, the detection chip is in the tray 21, and the sample injection port on the detection chip is communicated with the injection port 221 on the cover plate 22. In this embodiment, the phrase "the driving mechanism 32 is drivingly connected to the sample-adding arm 31 to selectively communicate the liquid outlet 3421 with the injection port 221 of one of the quality control liquid bottles 34" means that: when the driving mechanism 32 drives the sample-adding arm 31 to move, the plurality of quality control liquid bottles 34 can be driven to move together, so that the liquid outlet 3421 of one of the plurality of quality control liquid bottles 34 can be communicated with the injection port 221 on the cover plate 22.
In the initial state, different quality control liquids are respectively contained in the quality control liquid bottles 34, and when the quality control liquids are filled, the cover plate 22 is firstly switched to the avoiding position, then the detection chip is placed on the tray 21, and then the cover plate 22 is switched to the covering position. Then, a detection sample is injected into the detection chip, and the detection sample can be added into the detection chip from the injection port 221 through a sample injection needle or the like, or the detection sample can be added into the quality control liquid bottle 34 first, and then the detection sample can be added into the detection chip through the quality control liquid bottle 34. After the luminescence immunoassay analyzer operates for a period of time (for example, after the detection sample is separated), the driving mechanism 32 drives the sample adding arm 31 to move according to the quality control liquid to be added, so that the liquid outlet 3421 of one of the quality control liquid bottles 34 is communicated with the injection port 221, and then the liquid injection rod 33 applies an external force to the quality control liquid bottle 34 to make the liquid in the quality control liquid bottle 34 flow to the injection port 221, thereby completing the filling of the quality control liquid.
That is to say, the utility model discloses an among the luminescence immunoassay appearance testing process, to the different detection items, only need utilize actuating mechanism 32 drive application of sample arm 31 to remove for the liquid outlet 3421 and the filling opening 221 intercommunication of the quality control liquid bottle 34 of corresponding quality control liquid are equipped with, then utilize liquid injection pole 33 to exert external force to quality control liquid bottle 34 and can be to the corresponding quality control liquid of detection chip filling, whole process can realize no manual operation, and is easy to operate, can improve luminescence immunoassay appearance's detection efficiency, and can reduce luminescence immunoassay appearance's detection cost.
Further, the bracket assembly 20 in this embodiment further includes a first motor 23 and a second motor 24, wherein the first motor 23 is connected to the tray 21 for driving the tray 21 to rotate, so as to drive the detection chip mounted on the tray 21 to rotate. The second motor 24 is drivingly connected to the cover plate 22 through a transmission mechanism such as a lead screw, and further can drive the cover plate 22 to switch between a covering position and an avoiding position. Of course, in other embodiments, the second motor 24 may be a driving cylinder, and other modifications are within the scope of the present invention as long as they are within the spirit of the present invention.
In some embodiments, the quality control liquid bottle 34 includes a body 341 and a nozzle 342, the nozzle 342 is mounted on the body 341, and the liquid outlet 3421 is disposed on the nozzle 342, so that when in use, the nozzle 342 is pressed by the liquid injection rod 33 to eject the liquid in the body 341 from the liquid outlet 3421.
In order to install the quality control liquid bottles 34, the sample addition arm 31 in this embodiment is provided with a plurality of positioning holes 311, the quality control liquid bottles 34 are arranged in the positioning holes 311 in an inverted manner one by one (i.e. one quality control liquid bottle 34 is arranged in one positioning hole 311 in an inverted manner), when the driving mechanism 32 drives the sample addition arm 31 to move to a predetermined position, one liquid outlet 3421 in the plurality of quality control liquid bottles 34 is opposite to the injection port 221 so as to realize communication, and at this time, an external force, i.e. a pressing force, is applied to the quality control liquid bottles 34 through the liquid injection rod 33, so that the quality control liquid in the quality control liquid bottles 34 can be injected to the injection port 221, and then the detection chip is injected.
Optionally, the liquid injection assembly 30 in this embodiment further includes a spring 3302, the spring 3302 is installed in the positioning hole 311 and is abutted between the positioning hole 311 and the quality control liquid bottle 34, when the liquid injection rod 33 applies a pressing force to the quality control liquid bottle 34, the quality control liquid bottle 34 moves downward and presses the spring 3302, and after the spring 3302 is pressed to a certain position, the quality control liquid bottle 34 continues to move downward and presses the nozzle 342, so as to inject the quality control liquid in the quality control liquid bottle 34 into the injection port 221. When liquid injection rod 33 is far away from quality control liquid bottle 34, the spring 3302 can apply a restoring force to quality control liquid bottle 34, so that quality control liquid bottle 34 moves toward a direction far away from the detection chip to realize resetting.
In order to limit the quality control liquid bottle 34 and the spring 3302, in this embodiment, the positioning hole 311 is provided with a step hole, and when the device is installed, the spring 3302 is pressed against between the step and the quality control liquid bottle 34, so that the structure is stable and reliable.
Further, the sample adding arm 31 in this embodiment is rotatably or telescopically mounted on the base 11, and the driving mechanism 32 is drivingly connected to the sample adding arm 31 to drive the sample adding arm 31 to rotate or telescopically extend. When the sample addition arm 31 is telescopically mounted on the base 11, the driving mechanism 32 is used to drive the sample addition arm 31 to be telescopic, so as to drive the plurality of quality control liquid bottles 34 to move to switch the quality control liquid bottles 34 communicated with the injection ports 221. When the sample addition arm 31 is rotatably mounted on the base 11, the driving mechanism 32 is used to drive the sample addition arm 31 to rotate, so as to drive the plurality of quality control liquid bottles 34 to rotate to switch the quality control liquid bottles 34 communicated with the injection ports 221.
In this embodiment, the sample addition arm 31 is rotatably attached to the base 11. Alternatively, the driving mechanism 32 in this embodiment includes a third motor 321, a first gear 322, a second gear 323, a rotating shaft 324, and a chain 325. Wherein, third motor 321 installs on base 11, the cover is equipped with first gear 322 on the output shaft of third motor 321, pivot 324 rotationally installs on base 11, application of sample arm 31 fixed mounting is on pivot 324, second gear 323 cover is established on pivot 324, chain 325 is connected between first gear 322 and second gear 323, thus, when third motor 321 rotates, can drive first gear 322, chain 325 and second gear 323 rotate, and then can drive pivot 324 and install application of sample arm 31 rotation on pivot 324, moreover, the steam generator is simple in structure, and control accuracy is high.
Of course, in other embodiments of the present invention, the driving mechanism 32 can only include the motor and a rotating shaft, and the rotating shaft is driven by the motor to rotate, so as to rotate the sample adding arm 31 installed on the rotating shaft, and as long as it can drive other deformation modes of the sample adding arm 31, it is all within the protection scope of the present invention.
Further, when the sample-adding arm 31 is telescopically arranged on the base 11, the quality control liquid bottles 34 are arranged at intervals along the length direction of the sample-adding arm 31, and when the sample-adding arm 31 is telescopically arranged, the quality control liquid bottles 34 can be driven to switch positions to communicate with the injection port 221; when the sample addition arm 31 is rotatably disposed on the base 11, the quality control liquid bottles 34 are mounted on the sample addition arm 31 along the same circumference, and when the sample addition arm 31 rotates, the quality control liquid bottles 34 are driven to switch positions to communicate with the injection port 221.
Further, the liquid injection assembly 30 of the present invention further includes a substrate adding mechanism 35, and the substrate adding mechanism 35 includes a substrate adding needle 351, a substrate bottle 352, and a quantitative pump 353. Wherein the substrate sampling needle 351 is provided on the sampling arm 31, and the substrate sampling needle 351 is driven by the driving mechanism 32 to selectively communicate with the injection port 221; the substrate bottle 352 is provided to the base 11; the quantitative pump 353 is in communication with the substrate bottle 352 and the substrate sampling needle 351 through a tube (not shown).
When the driving mechanism 32 drives the sample adding arm 31 to move, the position of the substrate sample adding needle 351 can be adjusted, and then the substrate sample adding needle 351 can be driven to be communicated with the injection port 221, at the moment, the quantitative pump 353 works to add the substrate into the substrate sample adding needle 351, then the external force is applied to the substrate sample adding needle 351 through the sample adding rod 33, and the substrate in the substrate sample adding needle 351 can be added into the injection port 221. Of course, in other embodiments of the present invention, the external force may not be applied through the liquid injection rod 33 during the sample injection process of the substrate sample injection needle 351, and only the substrate needs to be pumped to the substrate sample injection needle 351 by the quantitative pump 353. The concrete sample adding mode is determined according to the concrete structure of the substrate sample adding needle 351, when the substrate sample adding needle 351 needs to be pressed to be in a sample adding structure, the substrate sample adding needle 351 is pressed by the sample adding rod 33, when the substrate sample adding needle 351 is in an empty tube structure, the substrate is poured into the substrate sample adding needle 351 by the quantitative pump 353, and then the substrate sample is dripped into the injection port 221.
Further, the base 11 is provided with the light-tight chamber 40, and the substrate bottle 352 is arranged in the light-tight chamber 40, because the substrate is easy to deteriorate after being exposed to light, in the embodiment, the light-tight chamber 40 is arranged on the base 11, and the substrate bottle 352 is arranged in the light-tight chamber 40, so that the substrate is prevented from deteriorating due to the fact that external light enters the light-tight chamber 40.
In order to replace the substrate bottle 352, the light-tight chamber 40 in this embodiment is provided with a chamber door 41, and when the body 341 is replaced, the chamber door 41 may be opened.
Referring to fig. 7 to 10, the substrate bottle 352 of the present embodiment includes a bottle body 3521 and a bottle cap 3522 covering the bottle body 3521, the bottle cap 3522 is installed in the light-tight chamber 40 by a lifting unit 354 and is connected to a constant volume pump 353 through a pipe, and the bottle body 3521 is replaceably installed in the light-tight chamber 40. When the substrates need to be replaced, the lifting assembly 354 is lifted, the bottle cap 3522 is lifted to separate the bottle cap 3522 from the bottle body 3521, then the bottle body 3521 is taken out, the substrates are poured into the bottle body 3521, or the bottle body 3521 is replaced by a new bottle body 3521 filled with the substrates and then placed back into the light-tight cabin 40, and the operation is simple and quick.
Optionally, the lifting assembly 354 in this embodiment may be a lifting cylinder, a telescopic rod, etc., as long as the other deformation modes under the concept of the present invention are all within the protection scope of the present invention.
Further, the liquid injection assembly 30 in this embodiment further includes a light-tight rod 36, the light-tight rod 36 is movably disposed on the sample injection arm 31 up and down and is driven by the driving mechanism 32 to move to above the injection port 221; the injection rod 33 is at least used for applying a pressing force to the sealing rod 36 so that the end of the sealing rod 36 seals the injection port 221. With this arrangement, after the substrate is injected into the injection port 221, the injection port 221 is sealed by driving the liquid injection rod 33 by the driving mechanism 32, so that the substrate can be further prevented from deterioration due to contact with external light, and the detection effect of the luminescence immunoassay analyzer in the present embodiment can be improved. Further, an elastic packing 361 or an elastic packing is provided at an end of the sealing rod 36, and the injection port 221 is easily sealed by the elastic packing 361 or the elastic packing. Optionally, the elastic sealing gasket 361 or the elastic sealing ring in this embodiment may be a rubber member, and may also be a silicone member.
Further, the liquid injection assembly 30 in this embodiment further includes a driving member, which is in driving connection with the liquid injection rod 33 to drive the liquid injection rod 33 to move up and down along the height direction of the luminescence immunoassay analyzer, so as to apply a pressing force to the quality control liquid bottle 34, the sealing rod 36, and the like. Optionally, the driving member includes a fourth motor 3301, and the fourth motor 3301 is connected to the liquid injection rod 33 through a screw rod or the like, so as to drive the liquid injection rod 33 to move up and down along the height direction of the luminescence immunoassay analyzer. Of course, in other embodiments of the present invention, the driving member may also be a lifting cylinder or the like.
Referring to fig. 7 again, the detecting assembly in this embodiment includes a PMT (photomultiplier tube) module 50, the PMT module 50 is provided with a lifting mechanism 51 and a close-coupled aperture 52, when in actual use, the lifting mechanism 51 drives the close-coupled aperture 52 to abut against the bottom of the tray 21, so that light emitted by the photomultiplier tube on the PMT module 50 can be irradiated from the close-coupled aperture 52 to the detecting chip on the tray 21 without being interfered by the outside, and the detecting accuracy of the luminescence immunoassay analyzer in this embodiment can be further improved. The aperture 52 in this embodiment is an elastic shading ring, and the lifting mechanism 51 may be a telescopic rod or a telescopic cylinder.
From the above description, it can be seen that the above-mentioned embodiments of the present invention achieve the following technical effects: the utility model discloses an in the luminescence immunoassay appearance testing process, to the different detection items, only need utilize actuating mechanism 32 drive application of sample arm 31 to remove, make the liquid outlet 3421 and the filling opening 221 intercommunication of the quality control liquid bottle 34 that is equipped with corresponding quality control liquid, then utilize liquid injection pole 33 to exert external force to quality control liquid bottle 34 can be to detecting the corresponding quality control liquid of chip filling, whole process can realize unmanned operation, and the operation is thus simple, can improve the detection efficiency of luminescence immunoassay appearance, and can reduce the detection cost of luminescence immunoassay appearance.
For ease of description, spatially relative terms such as "over 8230 \ 8230;,"' over 8230;, \8230; upper surface "," above ", etc. may be used herein to describe the spatial relationship of one device or feature to another device or feature as shown in the figures. It will be understood that the spatially relative terms are intended to encompass different orientations of the device in use or operation in addition to the orientation depicted in the figures. For example, if a device in the figures is turned over, devices described as "above" or "on" other devices or configurations would then be oriented "below" or "under" the other devices or configurations. Thus, the exemplary terms "at 8230; \8230; 'above" may include both orientations "at 8230; \8230;' above 8230; 'at 8230;' below 8230;" above ". The device may be otherwise variously oriented (rotated 90 degrees or at other orientations) and the spatially relative descriptors used herein interpreted accordingly.
It should be noted that the terms "first", "second", and the like are used to define the components, and are only used for convenience of distinguishing the corresponding components, and if not stated otherwise, the terms have no special meaning, and therefore, the scope of the present invention should not be construed as being limited.
The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention, and various modifications and changes may be made by those skilled in the art. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims (10)

1. A luminescence immunoassay analyzer, comprising:
a body (10), said body (10) comprising a base (11);
the detection device comprises a bracket assembly (20), wherein the bracket assembly (20) is arranged on the base (11), the bracket assembly (20) comprises a tray (21) and a cover plate (22), the tray (21) is rotatably arranged on the base (11), an installation part (211) for installing a detection chip is arranged on the tray (21), the cover plate (22) is provided with a covering position for covering the installation part (211) and an avoiding position for avoiding the installation part (211), and the cover plate (22) is provided with an injection port (221); and
the liquid injection device comprises a liquid injection assembly (30), wherein the liquid injection assembly (30) comprises a sample injection arm (31), a driving mechanism (32), a liquid injection rod (33) and a plurality of quality control liquid bottles (34), the sample injection arm (31) is movably arranged on the base (11) and is positioned above the bracket assembly (20), the quality control liquid bottles (34) are arranged on the sample injection arm (31) side by side, each quality control liquid bottle (34) comprises a liquid outlet (3421), the driving mechanism (32) is in driving connection with the sample injection arm (31) so as to selectively enable the liquid outlet (3421) of one of the quality control liquid bottles (34) to be communicated with the injection port (221), and the liquid injection rod (33) is at least used for applying external force to the quality control liquid bottles (34) to enable liquid in the quality control liquid bottles (34) to flow to the injection port (221).
2. The luminescence immunoassay analyzer of claim 1, wherein the quality control liquid bottle (34) comprises a bottle body (341) and a nozzle (342), the nozzle (342) is mounted on the bottle body (341), the liquid outlet (3421) is disposed on the nozzle (342), the nozzle (342) ejects the liquid in the bottle body (341) from the liquid outlet (3421) under the pressing force applied by the liquid injection rod (33);
the sample adding arm (31) is provided with a plurality of positioning holes (311), the quality control liquid bottles (34) are arranged in the positioning holes (311) in an inverted mode in a one-to-one correspondence mode, and when the driving mechanism (32) drives the sample adding arm (31) to move to a preset position, the liquid outlet (3421) of one of the quality control liquid bottles (34) is opposite to the injection port (221) so that communication can be achieved.
3. The luminescence immunoassay instrument of claim 1, wherein the sample application arm (31) is rotatably or telescopically mounted to the base (11), and the driving mechanism (32) is drivingly connected to the sample application arm (31) to drive the sample application arm (31) to rotate or telescopically extend.
4. The luminescence immunoassay analyzer according to claim 3, wherein the sample application arm (31) is rotatably disposed on the base (11), and a plurality of the quality control liquid bottles (34) are mounted on the sample application arm (31) along the same circumference.
5. The luminescence immunoassay analyzer of claim 1, wherein the liquid injection module (30) further comprises a substrate adding mechanism (35), the substrate adding mechanism (35) comprising:
a substrate sampling needle (351), wherein the substrate sampling needle (351) is arranged on the sampling arm (31), and the substrate sampling needle (351) is driven by the driving mechanism (32) to be communicated with the injection opening (221);
a substrate bottle (352), the substrate bottle (352) being provided to the base (11);
a quantitative pump (353), wherein the quantitative pump (353) is communicated with the substrate bottle (352) and the substrate sampling needle (351) through a pipeline.
6. The apparatus according to claim 5, wherein the base (11) is provided with a light-tight chamber (40), and the substrate bottle (352) is provided with the light-tight chamber (40).
7. The luminometric immunoassay analyzer of claim 6, wherein the substrate bottle (352) comprises a bottle body (3521) and a bottle cap (3522) covering the bottle body (3521), the bottle cap (3522) is mounted in the light-tight chamber (40) by a lifting assembly (354) and is connected with the dosing pump (353) by the pipe, and the bottle body (3521) is replaceably disposed in the light-tight chamber (40).
8. The luminescence immunoassay instrument of claim 1, wherein the injection assembly (30) further comprises a light-tight rod (36), the light-tight rod (36) is movably disposed up and down on the sample-adding arm (31) and moves to above the injection port (221) under the driving of the driving mechanism (32);
the liquid injection rod (33) is at least used for applying pressing force to the sealing rod (36) so that the end of the sealing rod (36) seals the injection port (221).
9. The luminiscence immunoassay instrument of any one of claims 1 to 8, further comprising a detection assembly, wherein the detection assembly comprises a PMT module (50), a lifting mechanism (51) and a light-tight ring (52) are arranged on the PMT module (50), and when the luminiscence immunoassay instrument is in operation, the lifting mechanism (51) is used for driving the light-tight ring (52) to abut against the bottom of the tray (21).
10. The luminescence immunoassay analyzer of any one of claims 1 to 9, wherein the injection assembly (30) further comprises a driving member, and the driving member is in driving connection with the injection rod (33) to drive the injection rod (33) to move up and down along the height direction of the luminescence immunoassay analyzer.
CN202221291596.1U 2022-05-23 2022-05-23 Luminous immunity analyzer Active CN217931700U (en)

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