CN217931035U - Tissue sample processing device - Google Patents

Abstract

The application provides a tissue sample processing device, which comprises a device body, a lysis tube and forceps; the device body is provided with an operation surface, at least one first cavity, at least one second cavity and at least one third cavity are arranged on the operation surface, wherein the first cavity is used for accommodating and limiting the cracking tube, the second cavity is used for accommodating and limiting the tweezers, and the third cavity is used for accommodating the physiological saline. The tissue sample processing apparatus that this application embodiment provided, tissue sample processing apparatus's operation face can contain normal saline, place tweezers and lysis tube, has integrated the required main apparatus of tissue processing, can directly wash and separate the tissue through tweezers in the first cavity that contains normal saline, sends to measurement personnel department after accomplishing the schizolysis through the lysis tube and detects, and is simple and convenient, and the sample is difficult for being contaminated.

Description

Tissue sample processing device

Technical Field

The present application relates to the medical field, and more particularly to tissue sample processing devices.

Background

The current intraoperative genetic testing techniques have begun to evolve, and many surgeries, such as some surgeries involving tumors, require intraoperative sampling for testing. Intraoperative genetic testing requires first processing a test sample, which typically includes the steps of: obtaining a tissue; washing the tissue with physiological saline; separating the tissue into appropriate sizes; adding the separated tissue into a cracking tube for cracking; and carrying out automatic detection after shaking and centrifuging. At present, the treatment of the detection sample is to distribute the tissue to a pathology department or a third-party institution for further treatment and detection after the tissue is obtained, which is time-consuming and labor-consuming; the sample detection is directly carried out in the operating room, local materials are needed to be obtained in the operating room, existing instruments in the operating room are combined to carry out sample detection, and the problems that the operation is not standard and the sample detection is easy to pollute are easily caused.

SUMMERY OF THE UTILITY MODEL

The embodiment of the application provides a tissue sample processing device to solve the technical problems that the processing of a detection sample in an operating room is irregular in operation and the detection sample is easy to pollute.

The embodiment of the application provides a tissue sample processing device, which comprises a device body, a lysis tube and forceps; the device body is provided with an operation surface, at least one first cavity, at least one second cavity and at least one third cavity are arranged on the operation surface, wherein the first cavity is used for containing and limiting the cracking tube, the second cavity is used for containing and limiting the forceps, and the third cavity is used for containing physiological saline.

In some embodiments of the present application, one side of the device body is further provided with a writable recording area.

In some embodiments of the present application, a fourth cavity is further provided within the device body for housing the lysis tube and the forceps.

In some embodiments of the present application, the fourth cavity is disposed opposite to the recording area.

In some embodiments of the present application, the device body is a box body, the device body is disposed opposite to an opening of the operation surface, and the fourth cavity is an inner cavity of the box body.

In some embodiments of the present application, a plurality of limiting mechanisms are disposed in the fourth cavity, and the lysis tube and the forceps are limited in the limiting mechanisms.

In some embodiments of the present application, the limiting mechanism includes a first limiting mechanism with one slot and a second limiting mechanism with two slots, the connecting end of the tweezers is clamped in the slot of the first limiting mechanism, and the two clamping ends of the tweezers are clamped in the slot of the second limiting mechanism.

In some embodiments of the present application, the limiting mechanism comprises a third limiting mechanism for limiting one end of the lysis tube and a fourth limiting mechanism for limiting the other end of the lysis tube.

In some embodiments of the present application, the third limiting mechanism is used for limiting one end of the cracking tube close to the device body, the fourth limiting mechanism is used for limiting the other end of the cracking tube close to the device body, and the side surface of the device body is provided with an opening opposite to one end or the other end of the cracking tube.

In some embodiments of the application, the opposite two side faces of the device body are provided with matched clamping blocks, and the adjacent device bodies are mutually limited through the clamping blocks.

In some embodiments of the present application, the first cavity has a shape that conforms to a shape of an end of the lysis tube.

In some embodiments of the present application, the cross-section of the second cavity is rectangular with a diagonal length equal to the width of the connecting end of the forceps.

Compared with the prior art, the technical scheme provided by the embodiment of the application has the following advantages:

the tissue sample processing apparatus that this application embodiment provided, tissue sample processing apparatus's operation face can contain normal saline, place tweezers and schizolysis pipe, has integrated the required main apparatus of tissue processing, can directly wash and separate the tissue through tweezers in the first cavity that contains normal saline, sends to measurement personnel department after accomplishing the schizolysis through the schizolysis pipe and detects, and is simple and convenient, and the sample is difficult for being contaminated.

Drawings

The accompanying drawings, which are incorporated in and constitute a part of this specification, illustrate embodiments consistent with the present application and together with the description, serve to explain the principles of the application.

In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, and it is obvious for those skilled in the art to obtain other drawings without inventive labor.

Fig. 1 is a schematic perspective view of a tissue sample processing device according to an embodiment of the present disclosure;

FIG. 2 is a schematic diagram illustrating a top view of a tissue sample processing device according to an embodiment of the present disclosure;

FIG. 3 is a schematic bottom view of a tissue sample processing device according to an embodiment of the present disclosure;

fig. 4 is a schematic diagram of a fixture block fitting structure of a tissue sample processing device according to an embodiment of the present disclosure;

fig. 5 is a schematic flow chart of a tissue sample processing method according to an embodiment of the present disclosure.

Detailed Description

The present application will be specifically explained below with reference to specific embodiments and examples, and the advantages and various effects of the present application will be more clearly apparent therefrom. It will be understood by those skilled in the art that these specific embodiments and examples are provided to illustrate and not to limit the application.

Throughout the specification, unless otherwise specifically noted, terms used herein should be understood as having meanings as commonly used in the art. Accordingly, unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this application belongs. If there is a conflict, the present specification will control.

Unless otherwise specifically indicated, various raw materials, reagents, instruments, equipment and the like used in the present application are either commercially available or can be prepared by existing methods.

Furthermore, it should be understood that the detailed description and specific examples, while indicating exemplary embodiments of the invention, are given by way of illustration and explanation only, and are not intended to limit the scope of the invention. In this application, where the context requires no explicit explanation, the use of directional words such as "upper" and "lower" in particular refers to the direction of the drawing in the figures. In addition, in the description of the present specification, the term "including" means "including but not limited to". Various embodiments of the present invention may exist in a range of forms; it should be understood that the description in range format is merely for convenience and brevity and should not be construed as an inflexible limitation on the scope of the invention; accordingly, the description of a range should be considered to have specifically disclosed all the possible subranges as well as individual numerical values within that range. For example, it is contemplated that the description of a range from 1 to 6 has specifically disclosed sub-ranges, such as from 1 to 3, from 1 to 4, from 1 to 5, from 2 to 4, from 2 to 6, from 3 to 6, etc., as well as single numbers within the stated range, such as 1, 2, 3, 4, 5, and 6, as applicable regardless of the range. In addition, whenever a numerical range is indicated herein, it is meant to include any number (fractional or integer) recited within the indicated range.

In the present application, "and/or" describes an association relationship of associated objects, meaning that there may be three relationships, for example, a and/or B, which may mean: a alone, A and B together, and B alone. Wherein A and B can be singular or plural.

In the present application, "at least one" means one or more, "a plurality" means two or more. "at least one," "at least one item(s) below," or similar expressions, refer to any combination of these items, including any combination of item(s) alone or item(s) in plurality. For example, "at least one (a), b, or c", or "at least one (a), b, and c", may each represent: a, b, c, a-b (i.e., a and b), a-c, b-c, or a-b-c, wherein a, b, and c may be single or plural, respectively.

In this application, relational terms such as "first" and "second", and the like, may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus. Without further limitation, an element defined by the phrases "comprising 8230; \8230;" 8230; "does not exclude the presence of additional like elements in a process, method, article, or apparatus that comprises the element.

At present, the sample detection treatment is directly carried out in an operating room, local materials are required to be obtained in the operating room, existing instruments in the operating room are combined to carry out the sample detection treatment, and the problems that the operation is not standard and the sample detection is easy to pollute are easily caused.

To solve the above technical problems, an embodiment of the present invention provides a tissue sample processing device and a tissue sample processing method, please refer to fig. 1-5, in which reference numerals in fig. 1-5 refer to: the device comprises a device body 100, a first cavity 110, a second cavity 120, a third cavity 130, a recording area 140, a fourth cavity 150, a first limiting mechanism 151, a second limiting mechanism 152, a third limiting mechanism 153, a fourth limiting mechanism 154, an opening 160, a fixture block 170, a lysis tube 200, forceps 300, a connecting end 310, a clamping end 320, a step S1, a step S2, a step S3 and a step S4.

In a first aspect, embodiments of the present application provide a tissue sample processing device comprising a device body 100, a lysis tube 200, and forceps 300; the device body 100 has an operation surface, the operation surface is provided with at least one first cavity 110, at least one second cavity 120 and at least one third cavity 130, wherein the first cavity 110 is used for accommodating and limiting the lysis tube 200, the second cavity 120 is used for accommodating and limiting the forceps 300, and the third cavity 130 is used for accommodating physiological saline.

The tissue sample processing device provided by the embodiment of the application is provided with the lysis tube 200 and the forceps 300, so that instruments do not need to be temporarily found in an operating room when the tissue sample needs to be processed in an operation; the first cavity 110, the second cavity 120, the third cavity 130 and the operation surface can limit the cracking tube 200, the forceps 300 and the physiological saline, so that the cracking tube 200 and the forceps 300 can be taken at any time only on the operation surface; must be equipped with normal saline in the operating room, take on the spot in adding third cavity 130, directly organize the sample processing in the normal saline environment in third cavity 130, rely on the operation panel just so can accomplish the whole operations of organizing sample processing, simple and convenient, the sample is difficult for being contaminated.

In some embodiments of the present application, three third cavities 130 are disposed on the operating face. The three third cavities 130 may provide three clean operating spaces so that the tissue sample may be rinsed multiple times.

In some embodiments of the present application, a writable recording area 140 is further disposed on one side of the device body 100.

The recording area 140 is used to record operation-related information, tissue-related information, and the like, as will be understood by those skilled in the art. The operating room is typically equipped with a water pen, a marker, etc. that can be used on site to write on the recording area 140.

In some embodiments of the present application, a fourth cavity 150 for accommodating the lysis tube 200 and the forceps 300 is further disposed in the device body 100. The fourth cavity 150 is arranged inside the device body 100, which is beneficial to fully utilizing the space and reducing the volume of the tissue sample processing device; the fourth cavity 150 may have only one, and may also contain the lysis tube 200 and the forceps 300, or may have a plurality of cavities, respectively containing the lysis tube 200 and the forceps 300. The fourth cavity 150 is used for accommodating the lysis tube 200 and the forceps 300 before the operation, so as to facilitate the usual accommodation; when the tissue sample is to be processed during the operation, the lysis tube 200 and the forceps 300 are removed from the fourth cavity 150 and placed in the first cavity 110 and the second cavity 120 for easy access.

In some embodiments of the present application, the fourth cavity 150 is disposed opposite to the recording area 140. Since the third cavity 130 is disposed on the operation surface, the third cavity 130 is required to contain saline, and occupies a relatively large volume, and the recording area 140 is only required to provide a writable plane, and occupies little volume, the fourth cavity 150 is disposed opposite to the recording area 140, which is beneficial to reducing the overall volume of the tissue sample processing device.

In some embodiments of the present application, the device body 100 is a box, a side opening 160 of the device body 100 opposite to the operation surface is disposed, and the fourth cavity 150 is an inner cavity of the box. The apparatus body 100 is provided in the form of a box, which is advantageous for saving materials and transportation. When the device is used, the lysis tube 200, the forceps 300 and the first cavity 110 and the second cavity 120 placed in the operation surface are taken out from the box body, and then the tissue sample processing can be started.

In some embodiments of the present application, a plurality of limiting mechanisms are disposed in the fourth cavity 150, and the lysis tube 200 and the forceps 300 are limited by the limiting mechanisms. The limiting mechanism can limit the lysis tube 200 and the forceps 300, so that the lysis tube 200 and the forceps 300 are prevented from moving, and transportation is facilitated. Those skilled in the art can understand that the limiting mechanism may be a groove adapted to the shape of the lysis tube 200 or the forceps 300, or may be a mechanism having a limiting effect, such as a buckle, a slot, an elastic rib, etc., and those skilled in the art can reasonably select the limiting mechanism according to actual needs.

In some embodiments of the present application, the limiting mechanism includes a first limiting mechanism 151 having one slot and a second limiting mechanism 152 having two slots, the connecting end 310 of the forceps 300 is clamped in the slot of the first limiting mechanism 151, and the two holding ends 320 of the forceps 300 are clamped in the slots of the second limiting mechanism 152.

As will be understood by those skilled in the art, the forceps 300 generally includes two long members, each of which has a certain elasticity, one ends of the long members are connected, the other ends of the long members are opposite to each other, and the other ends of the long members can be close to each other by external force so as to clamp an article; the end of the two members connected together is the connecting end 310, and the end of the two members that can grip an item is the holding end 320, and generally a pair of tweezers 300 has two holding ends 320.

In some embodiments of the present application, the first limiting mechanism 151 is a protrusion disposed in the fourth cavity 150, the first limiting mechanism 151 is recessed up and down to form a slot, and the connecting end 310 of the tweezers 300 can be inserted into the slot. Similarly, the second limiting mechanism 152 is also a protrusion disposed in the fourth cavity 150, the fourth limiting mechanism 154 is concave upwards and downwards to form two slots, and the two holding ends 320 of the forceps 300 can be inserted into the two slots respectively.

In some embodiments of the present application, the tissue sample processing device includes two forceps 300, two second cavities 120 are disposed on the operation surface, and two sets of first and second limiting mechanisms 151 and 152 are disposed in the fourth cavity 150.

It will be appreciated by those skilled in the art that the separation of the biological tissue may be accomplished by processing the biological tissue into small pieces with forceps 300. The two forceps 300 can respectively clamp two ends of the biological tissue and then tear the biological tissue, so that the biological tissue can be conveniently separated. It will be appreciated by those skilled in the art that a single forceps 300 may also be used to separate biological tissue, such as by direct pinching off of biological tissue with forceps 300 having sharp grasping ends 320.

In some embodiments of the present application, the limiting mechanism comprises a third limiting mechanism 153 for limiting one end of the lysis tube 200 and a fourth limiting mechanism 154 for limiting the other end of the lysis tube 200.

In some embodiments of the present application, the third limiting mechanism 153 is used for limiting the position of one end of the cracking tube 200 close to the device body 100, the fourth limiting mechanism 154 is used for limiting the position of the other end of the cracking tube 200 close to the device body 100, and the side of the device body 100 is provided with an opening 160 opposite to one end or the other end of the cracking tube 200.

It will be understood by those skilled in the art that the third limiting mechanism 153 and the fourth limiting mechanism 154 are used to limit the position of the lysis tube 200 close to the device body 100, so that the lysis tube 200 can be taken out from the lysis tube 200 away from the device body 100. The opening 160 formed on the side of the device body 100 is convenient for medical staff to extend fingers from the opening 160 into the fourth cavity 150, and directly poke one end or the other end of the lysis tube 200 to take out the lysis tube 200 from the first and second limiting mechanisms 151 and 152.

In some embodiments of the present application, the third limiting mechanism 153 is a limiting seat, two ends of the limiting seat are provided with protrusions, and a groove-shaped structure is formed between the two protrusions and between the limiting seats, so that one end of the cracking tube 200 can be embedded into the limiting seat.

In some embodiments of the present application, the fourth limiting mechanism 154 is composed of three protrusions, one of the protrusions is connected to the other end of the cracking tube 200 opposite to the opening 160, and the other two protrusions are connected to two sides of one end of the cracking tube 200, so as to prevent the cracking tube 200 from axial displacement and radial displacement, and limit the cracking tube 200.

In some embodiments of the present application, two opposite side surfaces of the device body 100 are respectively provided with a fitting block 170, and the adjacent device bodies 100 are mutually limited by the fitting blocks 170.

Referring to fig. 4, in some embodiments of the present application, two engaging blocks 170 disposed on the left side of the device body 100 can be just inserted between two engaging blocks 170 disposed on the right side of the device body 100, such that the tissue sample processing device adjacent to each other on the left and right sides can be mutually limited; the two latches 170 on the lower side of the device body 100 can be just inserted between the two latches 170 on the upper side of the device body 100, so that the tissue sample processing devices adjacent to each other up and down can be mutually limited. Therefore, the device bodies 100 placed in sequence can be mutually limited, and are not easy to displace in the transportation process, thereby being convenient for packaging and transportation. It should be noted that, the upper, lower, left and right directions described in the present application are all directions of the drawing, and should not be construed as limiting the essential aspects of the present application.

In some embodiments of the present application, the shape of the first cavity 110 is identical to the shape of one end of the lysis tube 200.

In some embodiments of the present application, the end shape of one end of the lysis tube 200 is: a cylindrical shape having a diameter uniformly increased from one end of the cracking tube 200 to the other end thereof. The first cavity 110 is in a truncated cone shape matched with one end of the cracking tube 200, so that the cracking tube 200 is stably limited.

In some embodiments of the present application, the cross section of the second cavity 120 is rectangular with a diagonal length equal to the width of the connection end 310 of the forceps 300, so as to facilitate stable position limitation of the forceps 300.

In a second aspect, an embodiment of the present application provides a tissue sample processing method, including the following steps:

s1: providing the aforementioned tissue sample processing device, providing a biological tissue;

s2: placing the lysis tube 200 and the forceps 300 into the first cavity 110 and the second cavity 120, respectively;

s3: providing normal saline and adding the normal saline into the third cavity 130, taking the forceps 300 to clamp the biological tissue, adding the biological tissue into the third cavity 130, immersing the biological tissue into the normal saline, and separating and rinsing the biological tissue;

s4: taking the lysis tube 200, adding the biological tissue into the lysis tube 200 for lysis, and delivering the lysis tube 200 to a detection person for detection.

The following will further describe the tumor-related surgery as an example.

In some embodiments of the present application, in step S1, the biological tissue is tumor tissue or tissue suspected of being tumor tissue on the patient, and the biological tissue is provided through the patient body.

In step S2, before the biological tissue is taken out, the lysis tube 200 is first placed in the first cavity 110, and the forceps 300 is placed in the second cavity 120, so that all the required instruments are integrated on the operation surface and can be taken out at any time.

In step S3, the saline comes from the operating room, which is well known to those skilled in the art to be stock saline.

In some embodiments of the present application, the biological tissue is separated by grasping both ends of the biological tissue with two forceps 300 and tearing the biological tissue. The purpose of isolating the biological tissue is to process the biological tissue to a size suitable for lysis.

In step S4, after the biological tissue is separated and rinsed, the lysis operation can be performed in situ through the lysis tube 200, and then the whole lysis tube 200 can be delivered to the inspector for inspection.

The previous description is only an example of the present application, and is provided to enable any person skilled in the art to understand or implement the present application. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the generic principles defined herein may be applied to other embodiments without departing from the spirit or scope of the application. Thus, the present application is not intended to be limited to the embodiments shown herein but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.

Claims (12)

1. A tissue sample processing device, comprising a device body, a lysis tube, and forceps; the device body is provided with an operation surface, at least one first cavity, at least one second cavity and at least one third cavity are arranged on the operation surface, wherein the first cavity is used for containing and limiting the cracking tube, the second cavity is used for containing and limiting the forceps, and the third cavity is used for containing physiological saline.

2. The tissue sample processing device according to claim 1, wherein one face of said device body is further provided with a writable recording area.

3. The tissue sample processing device according to claim 2, wherein a fourth cavity is further disposed within the device body for housing the lysis tube and the forceps.

4. The tissue sample processing device according to claim 3, wherein the fourth cavity is disposed opposite the recording region.

5. The tissue sample processing device according to claim 3, wherein the device body is a cartridge, a side of the device body opposite to the operation surface is open, and the fourth cavity is an inner cavity of the cartridge.

6. The tissue sample processing device according to claim 3, wherein a plurality of limiting mechanisms are arranged in the fourth cavity, and the lysis tube and the forceps are limited in the limiting mechanisms.

7. The tissue specimen processing device according to claim 6, wherein the limiting mechanism comprises a first limiting mechanism with one slot and a second limiting mechanism with two slots, the connecting end of the forceps is clamped in the slot of the first limiting mechanism, and the two holding ends of the forceps are clamped in the slots of the second limiting mechanism.

8. The tissue sample processing device according to claim 6, wherein the limiting mechanism comprises a third limiting mechanism for limiting one end of the lysis tube and a fourth limiting mechanism for limiting the other end of the lysis tube.

9. The tissue sample processing device according to claim 8, wherein the third limiting mechanism is used for limiting one end of the lysis tube close to the device body, the fourth limiting mechanism is used for limiting the other end of the lysis tube close to the device body, and the side surface of the device body is provided with an opening opposite to one end or the other end of the lysis tube.

10. The tissue sample processing device according to claim 1, wherein the opposing sides of the device body are provided with engaging locking blocks, and adjacent device bodies are mutually limited by the locking blocks.

11. The tissue sample processing device according to claim 1, wherein the first cavity has a shape that conforms to a shape of an end of the lysis tube.

12. The tissue sample processing device according to claim 1, wherein the cross-section of the second cavity is rectangular with a diagonal length equal to the width of the connecting end of the forceps.

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