CN217885995U

CN217885995U - Multifunctional animal behavioral testing device for cerebral ischemia

Info

Publication number: CN217885995U
Application number: CN202220356630.2U
Authority: CN
Inventors: 李轶; 钟伟杰; 杨晓笙; 张文川
Original assignee: Ninth Peoples Hospital Shanghai Jiaotong University School of Medicine
Current assignee: Ninth Peoples Hospital Shanghai Jiaotong University School of Medicine
Priority date: 2022-02-22
Filing date: 2022-02-22
Publication date: 2022-11-25
Anticipated expiration: 2032-02-22

Abstract

The utility model relates to the technical field of medical equipment. The multifunctional cerebral ischemia animal ethology detection device comprises a balance wood rod and a buffer box, wherein the buffer box comprises a box body and a flexible padding placed in the box body; two ends of the balance wood rod are respectively connected with the box body through two vertically arranged support rods; threading pieces are arranged on the two supporting rods, and threading holes for threading suspension wires are formed in the threading pieces on the two supporting rods; the turnover box also comprises a hard plate body for turning over an animal, and the hard plate body is detachably connected with the box body. The utility model discloses a setting of buffering box for the cushioning effect when balance beam and suspension experiment laboratory mouse drop and should adapt to animal and device in advance when carrying out the behavioural experiment. The suspension experiment was performed by means of a suspension wire. The positive reflection experiment was performed through a hard plate. The balance beam experiment was performed by a balance beam.

Description

Multifunctional animal behavioral testing device for cerebral ischemia

Technical Field

The utility model relates to the field of medical equipment, specifically be behavioural detection device.

Background

The existing animal ethology devices are various, but although the ethology devices on the market are simple in composition, the price is expensive, one device can only complete the same ethology experiment generally, and the device needs to be unfolded again when the next item needs to be carried out, so that the experiment is time-consuming and labor-consuming.

The animal disease model is important as a behavior detection, particularly the cerebral ischemia animal model, and in behavior monitoring, due to individual differences, multiple behavior co-monitoring is of great reference significance.

Cerebrovascular disease is the first five diseases of mortality, and has a poor prognosis, with ischemic stroke being particularly preferred. The problem of ischemic stroke is getting worse as the population ages, but the therapeutic modality for ischemic stroke remains to be explored further. The research on a disease depends on the development of basic experiments, so that an ischemic stroke model is very critical, and the evaluation of the ischemic stroke model and the establishment of treatment effect need the auxiliary verification of means such as ethology, histology and the like.

Balance beam experiments and suspension experiments are used as classical ethological methods for ischemic stroke, and righting reflex is also an important monitoring means in a neonatal mouse ischemic-hypoxic encephalopathy model.

CN213726635U discloses a rat brain injury after nerve function scoring table, which can realize a balance beam experiment of a cerebral ischemia animal, but can not realize a suspension experiment and a righting reflex experiment, and has a single function.

At present, a behavioural detection device which can integrate balance beam experiments, suspension experiments and righting reflex into a whole and is suitable for cerebral ischemia is lacked.

SUMMERY OF THE UTILITY MODEL

Problem to prior art existence, the utility model provides a multi-functional cerebral ischemia animal behavioural test device to solve above at least one technical problem.

In order to achieve the purpose, the utility model provides a multifunctional cerebral ischemia animal behavior detection device, which comprises a balance wood rod and is characterized by also comprising a buffer box, wherein the buffer box comprises a box body and a flexible pad material arranged in the box body;

two ends of the balance wood rod are respectively connected with the box body through two vertically arranged support rods;

threading pieces are arranged on the two supporting rods, threading holes penetrating through the suspension wires are formed in the threading pieces on the two supporting rods, and the threading pieces on the two supporting rods are connected through the suspension wires penetrating through the threading holes;

the turnover box also comprises a hard plate body used for turning over animals, and the hard plate body is detachably connected with the box body.

The utility model discloses a setting of buffering box for the cushioning effect when balance beam and suspension experiment laboratory mouse drop and should adapt to animal and device in advance when carrying out the behavioural experiment.

The suspension experiment was performed by means of a suspension wire. The righting reflection experiment is carried out through a hard plate body. The balance beam experiment was performed by a balance beam.

Further preferably, the flexible padding comprises a sponge.

Further preferably, the two support rods are respectively a first support rod and a second support rod, the first support rod is installed at the corner of the left rear side of the box body, and the second support rod is installed in the central area of the right side plate of the box body.

Further preferably, a dark box is installed at one end of the balance wood pole, and an opening of the dark box faces the balance wood pole.

Because the laboratory mouse has light shading, can move toward the magazine when carrying out the balance beam experiment. The walking direction of the experimental mouse is induced.

Further preferably, a first camera is installed in the camera bellows, and the collecting direction of the first camera faces the balance wood rod.

Is convenient for collecting the balance beam experiment of the experimental mouse.

Further preferably, a second camera is mounted on any one of the two support rods, and the second camera faces the suspension line.

The collection of hanging experimental pictures is convenient to realize.

Further preferably, the box body is provided with a slot for inserting the support rod. The assembly is convenient.

Further preferably, both ends of the balance wood pole are detachably connected with the support poles respectively.

Further preferably, one end of the hard plate body is hinged with the top of the rear side wall of the box body;

when the hard plate body is horizontally arranged, the hard plate body is in lap joint with the front side wall of the box body.

The hard plate body can be conveniently turned over and removed from the box body or the overlapped switching can be conveniently put.

Or the hard plate body comprises a front plate body and a rear plate body, the front plate body is hinged with the top of the front side of the box body, and the rear plate body is hinged with the top of the rear side of the box body;

the front plate body and the rear plate body are detachably connected and spliced to form the hard plate body.

When the experiment is just turned over to needs to be realized being convenient for, plate body and back plate body overturn before realizing, plate body and back plate body upset to the top of box body before realizing.

Has the advantages that:

1) Three behaviours are improved into one device, so that the experimental operation is convenient, and the result is more sufficient due to the combination of multiple behaviours.

2) And objectively recording the behavioristic experiment by using a camera for subsequent analysis.

3) The whole device reduces the occupied area and the use cost.

4) The details of each part meet the requirements of behavioral monitoring, such as animal pre-adaptation in advance, animal damage prevention and the like.

Drawings

Fig. 1 is a schematic structural diagram of embodiment 1 of the present invention;

fig. 2 is a schematic structural diagram of embodiment 3 of the present invention.

Wherein: 1 is the box body, 2 is the balance wood pole, 3 is the bracing piece, 4 is the threading piece, 5 is the suspension wire, 6 is the stereoplasm plate body, 7 is the camera, 8 is the second camera, 9 is the bolt, 61 is preceding plate body, 62 is the back plate body.

Detailed Description

The present invention will be further described with reference to the accompanying drawings.

Referring to fig. 1, specific example 1: multifunctional cerebral ischemia animal behavioural test device, including the buffer box, the buffer box includes box body 1 and places the flexible pad in box body 1. The box body 1 has a length of 85cm, a width of 40cm and a height of 30cm. The height of the flexible padding may be 20cm.

Still include balanced wooden pole 2, the both ends of balanced wooden pole 2 link to each other with box body 1 through two bracing pieces 3 of vertical setting respectively. The balance wood rod 2 is in a cuboid shape. The balance bar 2 has dimensions of 80cm × 1cm × 1cm.

All install threading piece 4 on two spinal branch vaulting poles, set up the through wires hole that passes suspension line 5 on the threading piece 4 on two spinal branch vaulting poles 3, threading piece 4 on two spinal branch vaulting poles links to each other through the suspension line 5 that passes the through wires hole. The support rod is in a cuboid shape. The support rods had dimensions of 60cm by 4cm.

The turnover box also comprises a hard plate body 6 for turning over animals, wherein the hard plate body 6 is detachably connected with the box body 1.

The suspension experiment was performed by means of the suspension wire 5. The positive reflection experiment was performed through the hard plate 6. The balance beam experiment was performed by the balance beam 2.

The flexible padding comprises sponge.

The two support rods are respectively a first support rod and a second support rod, the first support rod is installed at the corner of the left rear side of the box body 1, and the second support rod is installed in the central area of the right side plate of the box body 1. The first supporting rod and the second supporting rod are provided with scale marks which are vertically arranged. The threading piece is detachably connected with the two support rods. The height of the suspension line can be conveniently adjusted.

A dark box 7 is arranged at one end of the balance wood rod 2, and the opening of the dark box 7 faces the balance wood rod 2. Because the laboratory mouse has light shading, can move toward the magazine when carrying out the balance beam experiment. The walking direction of the experimental mouse is induced. The camera bellows is installed above any one of the two support rods. The end part of the balance wood rod partially extends into the dark box.

The camera bellows includes the bottom plate, and the bottom plate is connected with preceding curb plate, posterior lateral plate and left side board, and preceding curb plate articulates there is the apron. The inner walls of the dark box are covered with black shading plates. The top of the front side plate and the top of the rear side plate are connected with a right side plate, and the lower end of the right side plate is provided with an opening. The experimental animal can enter the device conveniently.

Install first camera in the camera bellows, the collection direction of first camera is towards balanced wooden pole 2. Is convenient for collecting the balance beam experiment of the experimental mouse. The first support bar may be a hollow support bar. The lead wires of the first camera and the second camera extend from the inside of the first support rod.

A second camera 8 is mounted on any one of the two support rods, the second camera 8 facing the suspension wire 5. The collection of hanging experimental pictures is convenient to realize.

The box body 1 is provided with a slot for inserting the supporting rod. The assembly is convenient.

The both ends of balanced wooden pole can be dismantled with the bracing piece respectively and be connected.

The working principle is as follows:

in the test of the balance beam,

put the experimental animals to the one side that the camera bellows was kept away from to balanced wooden pole, according to light-shading, the experimental animals can be along balanced wooden pole toward the camera bellows motion, through the motion gesture and the time of experimental animals on balanced wooden pole, as the analysis reference. (in this case, the rigid plate is not located above the flexible padding.)

When the suspension test is carried out, the suspension test,

the upper limbs of the experimental animals are placed on the hanging lines, and whether the experimental animals can be held on the hanging lines or not, hanging time and the like are recorded and used as analysis references. (in this case, the rigid plate is not located above the flexible padding.)

When the reflection is turned over, the reflection light is reflected,

the experimental animal is placed on the hard plate body in a lying posture, and the turning time and the turning posture of the experimental animal are recorded and used as analysis references. (in this case, the rigid plate is located above the flexible mat and is lapped on the box body.)

In embodiment 2, based on embodiment 1, one end of the hard plate is hinged to the top of the rear side wall of the box body; when the hard plate body is horizontally arranged, the hard plate body is lapped with the front side wall of the box body. The switching of the hard plate body from the box body in a turnover manner or in a placing and overlapping manner is convenient to realize.

Referring to fig. 2, in embodiment 3, based on embodiment 1, the hard plate includes a front plate and a rear plate, the front plate 61 is hinged to the top of the front side of the box, and the rear plate 62 is hinged to the top of the rear side of the box; the front plate body and the rear plate body are detachably connected and spliced to form a hard plate body. When the experiment is just turned over to needs to be realized being convenient for, plate body and back plate body overturn before realizing, plate body and back plate body upset to the top of box body before realizing. Preferably, the front plate body and the rear plate body are detachably connected with the bolt seat through bolts 9. The front plate body and the rear plate body are provided with bolt seats which penetrate through bolts. Bolt seats are installed at the left end and the right end of the front plate body and the rear plate body. The bolt is connected with the front plate body or the rear plate body through the connecting rope.

In specific embodiment 4, on the basis of specific embodiment 1, the top of the rear side plate of the box body is higher than the top of the front side plate of the box body, the rear side plate of the box body is provided with a strip-shaped opening penetrating through the hard plate body, and the front end of the hard plate body penetrates through the strip-shaped opening and is lapped on the front side plate of the box body. The front end of the hard plate body is provided with a limiting flanging extending upwards. The limiting flanging prevents the hard plate body from retreating from the strip-shaped opening.

The foregoing is only a preferred embodiment of the present invention, and it should be noted that, for those skilled in the art, a plurality of improvements and decorations can be made without departing from the principle of the present invention, and these improvements and decorations should also be regarded as the protection scope of the present invention.

Claims

1. The multifunctional cerebral ischemia animal ethology detection device comprises a balance wood rod and is characterized by further comprising a buffer box, wherein the buffer box comprises a box body and a flexible pad placed in the box body;

the turnover box also comprises a hard plate body used for turning over an animal, and the hard plate body is detachably connected with the box body;

the animals were laboratory mice.

2. The multifunctional behavioral testing device for cerebral ischemia animals according to claim 1, characterized in that: the flexible padding comprises a sponge.

3. The multifunctional behavioral testing device for cerebral ischemia animals according to claim 1, characterized in that: two bracing pieces are first bracing piece and second bracing piece respectively, first bracing piece is installed the bight at the left rear of box body, the second bracing piece is installed the central zone of the right side board of box body.

4. The multifunctional behavioral testing device for cerebral ischemia animals according to claim 1, characterized in that: a camera bellows is installed at one end of the balance wood rod, and an opening of the camera bellows faces the balance wood rod.

5. The multifunctional behavioral testing device for cerebral ischemia animals according to claim 4, characterized in that: install first camera in the camera bellows, the collection direction of first camera is towards balanced vaulting pole.

6. The multifunctional behavioral testing apparatus for cerebral ischemia animals according to claim 1, characterized in that: and a second camera is arranged on any one of the two support rods, and faces the suspension line.

7. The multifunctional behavioral testing device for cerebral ischemia animals according to claim 1, characterized in that: the box body is provided with a slot for inserting the supporting rod.

8. The multifunctional behavioral testing device for cerebral ischemia animals according to claim 1, characterized in that: the two ends of the balance wood rod are detachably connected with the supporting rods respectively.

9. The multifunctional behavioral testing device for cerebral ischemia animals according to claim 1, characterized in that: one end of the hard plate body is hinged with the top of the rear side wall of the box body;

10. The multifunctional behavioral testing apparatus for cerebral ischemia animals according to claim 1, characterized in that: the hard plate body comprises a front plate body and a rear plate body, the front plate body is hinged with the top of the front side of the box body, and the rear plate body is hinged with the top of the rear side of the box body;