CN217879016U - Blood sample analysis module - Google Patents
Blood sample analysis module Download PDFInfo
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- CN217879016U CN217879016U CN202221116990.1U CN202221116990U CN217879016U CN 217879016 U CN217879016 U CN 217879016U CN 202221116990 U CN202221116990 U CN 202221116990U CN 217879016 U CN217879016 U CN 217879016U
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Abstract
The application provides a blood sample analysis module, which comprises a shell and an enclosing wall assembly, wherein a cavity is arranged in the shell, and is provided with a first through hole, a second through hole and a third through hole; the wall assembly is arranged in the cavity and is in contact with the cavity to form a standard cavity and a contrast cavity, the first through hole and the second through hole are communicated with the standard cavity, and the third through hole is communicated with the contrast cavity; the wall of the standard cavity and the wall of the contrast cavity are both provided with electrode assemblies; the week side in the standard chamber of enclosure subassembly and/or contrast chamber is equipped with first pipeline and second pipeline, first pipeline embedding first through-hole, second pipeline embedding second through-hole, and first pipeline and second pipeline all communicate standard chamber. The blood sample analysis module that this application embodiment provided forms standard chamber and contrast chamber through setting up the enclosure subassembly in the casing to set up the first pipeline and the second pipeline in intercommunication standard chamber on the enclosure subassembly, make the outside liquid of blood sample analysis module can flow in the outflow standard chamber from first pipeline and second pipeline, realize repeated measurement many times.
Description
Technical Field
The application relates to the technical field of medical equipment, in particular to a blood sample analysis module.
Background
In medical diagnosis, the determination of some indicators of blood samples is important in medical diagnosis and therapy, such as pH, hematocrit, ion concentration (K +, na +, cl-, ca) 2 (+) glucose, lactic acid, and O 2 、CO 2 Partial pressure, etc.
The blood-gas biochemical test card is widely used in the medical industry, integrates biochemical test electrodes, is cleaned by cleaning fluid, is calibrated by calibration fluid, and then is used for testing the test fluid (blood). The waste liquid in the test process is stored in the test card, however, the test card can only finish single round or few round measurement generally based on the limited capacity in the test card, the measurement times are limited, and the improvement of the test efficiency is not facilitated.
SUMMERY OF THE UTILITY MODEL
The application aims at providing a blood sample analysis module to solve the defect that the biochemical test card of blood gas can only accomplish single round or few rounds of measurement generally.
The embodiment of the application provides a blood sample analysis module, which comprises a shell and a wall assembly, wherein a cavity is arranged in the shell, and a first through hole, a second through hole and a third through hole are formed in the shell; the wall assembly is arranged in the cavity and is in contact with the cavity to form a standard cavity and a contrast cavity, the first through hole and the second through hole are communicated with the standard cavity, and the third through hole is communicated with the contrast cavity; the cavity walls of the standard cavity and the contrast cavity are provided with electrode assemblies; wherein, the enclosure subassembly the standard chamber and/or week side of contrast chamber is equipped with first pipeline and second pipeline, first pipeline embedding first through-hole, the embedding of second pipeline the second through-hole, just first pipeline with the second pipeline all communicates the standard chamber.
The embodiment of the application provides a blood sample analysis module, through set up the enclosure subassembly in order to form standard chamber and contrast chamber in the cavity in the casing, and through first pipeline and the second pipeline that sets up the standard chamber of intercommunication on the enclosure subassembly, the first through-hole of first pipeline embedding casing, the second through-hole of second pipeline embedding casing, in order to communicate the casing inside and outside, make the outside liquid of blood sample analysis module can flow in from first pipeline and second pipeline and flow out standard chamber, and the liquid of holding in advance in outside liquid or the blood sample analysis module can flow in contrast chamber from the third through-hole. Meanwhile, the cavity walls of the standard cavity and the contrast cavity are provided with electrode assemblies, so that the blood sample analysis module can complete corresponding measurement operation, liquid in the standard cavity cannot be stored in the blood sample analysis module after measurement is completed, and the size of the blood sample analysis module can be greatly reduced. Liquid in the standard cavity can flow in and flow out blood sample analysis module through first pipeline and second pipeline respectively for blood sample analysis module can realize many times of repeated measurements, has greatly improved the measurement number of times of blood sample analysis module, need not frequently to change blood sample analysis module, and efficiency of software testing is high.
Drawings
In order to more clearly illustrate the technical solutions in the embodiments of the present application, the drawings needed to be used in the embodiments will be briefly described below. It is obvious that the drawings in the following description are only some embodiments of the application, and that for a person skilled in the art, other drawings can be derived from them without inventive effort.
FIG. 1 is a schematic diagram of a blood sample analysis module according to some embodiments of the present disclosure;
FIG. 2 is a schematic diagram showing the blood sample analyzing module of FIG. 1;
FIG. 3 is a cross-sectional view of a blood sample analysis module according to some embodiments of the present application;
FIG. 4 is a schematic structural view of a fence assembly according to some embodiments of the present application;
FIG. 5 isbase:Sub>A schematic cross-sectional view along A-A of the enclosure assembly of FIG. 4;
FIG. 6 is a schematic view of a first housing according to some embodiments of the present disclosure;
FIG. 7 is a schematic cross-sectional view of another embodiment of a blood sample analysis module of the present application;
FIG. 8 is a schematic view of a first housing in accordance with still further embodiments of the present application;
FIG. 9 is a schematic diagram of a portion of a blood sample analysis module according to some embodiments of the present application.
Detailed Description
The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application. It should be apparent that the described embodiments are only some of the embodiments of the present application, and not all of the embodiments. All other embodiments obtained by a person of ordinary skill in the art based on the embodiments in the present application without making any creative effort belong to the protection scope of the present application.
Reference herein to "an embodiment" means that a particular feature, structure, or characteristic described in connection with the embodiment can be included in at least one embodiment of the application. The appearances of the phrase in various places in the specification are not necessarily all referring to the same embodiment, nor are separate or alternative embodiments mutually exclusive of other embodiments. It is explicitly and implicitly understood by one skilled in the art that the embodiments described herein may be combined with other embodiments.
The "blood sample analysis module" used herein may be referred to as a "blood gas biochemical test card" or a "test card". The blood sample analysis module can be matched with a blood gas analysis device for measuring the pH value, the hematocrit and the ion concentration (K +, na +, cl-Ca) in a blood sample 2 (+) glucose, lactic acid, and O 2 、CO 2 Partial pressure, etc. The blood sample analysis module can generally utilize an electrochemical method or an alternating current impedance method to complete the parameter measurement.
As used herein, the "blood gas analyzing apparatus" may be referred to as a "blood gas analyzer" or a "blood gas biochemical analyzer" and utilizes a blood gas analyzing technique. The blood gas analysis technology is applied to blood gas analysis equipmentAlternatively, the concentration of H + in the blood sample, dissolved gases in the blood (mainly CO) can be measured 2 、O 2 Etc.) and other parameters, etc., which can directly reflect the function of pulmonary ventilation and the acid-base equilibrium state thereof, and the adopted specimen is usually a blood sample.
Referring to fig. 1, fig. 1 is a schematic diagram of a blood sample analysis module 100 according to some embodiments of the present disclosure, the blood sample analysis module 100 generally including a housing 10 and a wall assembly 30.
A chamber 101 is disposed in the housing 10, and the fence assembly 30 is disposed in the chamber 101 and contacts the chamber 101 to form a standard chamber 301 and a reference chamber 302. The housing 10 is further provided with a first through hole 110, a second through hole 120 and a third through hole 130, wherein the first through hole 110 and the second through hole 120 are communicated with the standard cavity 301, and the third through hole 130 is communicated with the comparison cavity 302.
The external liquid of the blood sample analysis module 100 can flow into and out of the standard chamber 301 through the first through hole 110 and the second through hole 120, and the external liquid or the liquid pre-contained in the blood sample analysis module 100 can flow into the control chamber 302 through the third through hole 130. Further, the wall of each of the standard chamber 301 and the control chamber 302 is provided with an electrode assembly 50, so that the blood sample analysis module 100 can perform corresponding measurement operations. It can be understood that the external liquid may be a cleaning liquid, a calibration liquid, a testing liquid, etc., which flows into the standard cavity 301 from the outside of the blood sample analysis module 100, and can be cleaned, calibrated, tested, etc. by the electrode assembly 50, after the measurement, the liquid in the standard cavity 301 can flow out of the blood sample analysis module 100, and will not be stored inside the blood sample analysis module 100, so as to greatly reduce the volume of the blood sample analysis module 100. The liquid in the standard cavity 301 can flow into and out of the blood sample analysis module 100, so that the blood sample analysis module 100 can realize repeated measurement for many times, the measurement times of the blood sample analysis module 100 are greatly improved, the blood sample analysis module 100 does not need to be frequently replaced, and the measurement efficiency is high.
In one embodiment, the electrode assembly 50 generally includes a first set of test electrodes 51 exposed in the reference chamber 301 and a second set of test electrodes 52 exposed in the control chamber 302.
In an embodiment, the housing 10 may further include a fourth through hole 140 communicating with the chamber 101, and the fourth through hole 140 is not communicated with the standard chamber 301 and the control chamber 302. The electrode assembly 50 may further include a third testing electrode set 53 exposed in the fourth through hole 140, that is, the third testing electrode set 53 may be exposed to the outside of the blood sample analysis module 100 through the fourth through hole 140, so that the blood sample analysis module 100 can be connected to a blood gas analysis apparatus through the third testing electrode set 53 to conduct signals related to the test. The first test electrode group 51 and the second test electrode group 52 are respectively signal-connected to the third test electrode group 53.
Further, the surrounding side of the standard chamber 301 and/or the control chamber 302 of the enclosure assembly 30 is provided with a first pipe 310 and a second pipe 320, the first pipe 310 is embedded in the first through hole 110, the second pipe 320 is embedded in the second through hole 120, and both the first pipe 310 and the second pipe 320 are communicated with the standard chamber 301, so that the external liquid of the blood sample analysis module 100 can flow into and out of the standard chamber 301 from the first pipe 310 and the second pipe 320. Preferably, the perimeter side of the standard cavity 301 of the fence assembly 30 is provided with a first conduit 310 and a second conduit 320.
It is understood that in the embodiment of the present application, all directional indications (such as up, down, left, right, front, rear, 8230) \8230;) are used only to explain the relative positional relationship between the components in a certain posture (as shown in the drawing), the motion situation, etc., and if the certain posture is changed, the directional indications are correspondingly changed.
Referring to fig. 2, fig. 2 is a schematic exploded view of the blood sample analysis module 100 in the embodiment of fig. 1, and the housing 10 generally includes a first housing 11 and a second housing 12 disposed on one side of the first housing 11. The first shell 11 can be connected with the second shell 12 through connection modes such as screw joint, insertion, buckle, bonding, welding and the like, and is matched with the second shell to form a cavity 101. Of course, in other embodiments, the first housing 11 and the second housing 12 may be a unitary structure.
The first housing 11 may be made of a hard material such as plastic, resin, or polymer. For example, the first housing 11 may be made of ABS (Acrylonitrile Butadiene Styrene), PDMS (Polydimethylsiloxane), PC (Polycarbonate), PMMA (Polymethyl methacrylate), PS (General purpose polystyrene), PP (Polypropylene), COC (polymers of cyclo olefin copolymer), etc., and may be formed by injection molding, numerical control machining, or 3D printing, etc.
The material of the second housing 12 may be the same as or different from that of the first housing 11. Preferably, the second case 12 may be a circuit board provided with the electrode assembly 50, that is, the circuit board is provided with a first test electrode group 51, a second test electrode group 52 and a third test electrode group 53, respectively, wherein the first test electrode group 51 and the second test electrode group 52 are provided on the same side of the circuit board, that is, the second case 12; the third testing electrode group 53 and the first testing electrode group 51 may be disposed on the same side of the circuit board, i.e., the second casing 12, or disposed on two opposite sides of the second casing 12.
The first through hole 110 and the second through hole 120 respectively penetrate through the second housing 12 to communicate with the standard chamber 301, and the third through hole 130 penetrates through the first housing 11 to communicate with the reference chamber 302.
Referring to fig. 3, fig. 3 is a schematic cross-sectional view of a blood sample analysis module 100 according to some embodiments of the present disclosure, in which a first receiving cavity 11a and a second receiving cavity 11b are respectively disposed on two opposite sides of a first housing 11, and a second housing 12 is at least partially embedded in the first receiving cavity 11a and surrounds the first housing 11 to form a cavity 101. In other words, a first accommodating cavity 11a is disposed on a side of the first housing 11 close to the second housing 12, and a second accommodating cavity 11b is disposed on a side of the first housing 11 away from the second housing 12. The wall assembly 30 is disposed between the first housing 11 and the second housing 12, and abuts against two opposite sides of the cavity 101 to form the standard cavity 301 and the comparison cavity 302, that is, two opposite sides of the wall assembly 30 respectively abut against the first housing 11 and the second housing 12 to form the standard cavity 301 and the comparison cavity 302.
Preferably, the second housing 12 is embedded in the first receiving cavity 11a, and an outer periphery of the second housing 12 is matched with a cavity wall of the first receiving cavity 11a in shape. In an embodiment, the second housing 12 may be fixedly connected to the wall of the first accommodating cavity 11a by screwing, inserting, fastening, bonding, welding, and the like. For example, at least one assembling structure (e.g., a positioning column, a positioning hole, etc.) is disposed on the wall of the first receiving cavity 11a, and a connecting structure (e.g., a positioning column, a positioning hole, etc.) adapted to the positioning structure is disposed on the second housing 12. The assembling structure and the connecting structure cooperate to realize the assembling connection of the cavity wall of the first accommodating cavity 11a and the second housing 12. Preferably, the assembling structure and the connecting structure may be in a fool-proof manner to avoid a reverse assembling phenomenon when the second housing 12 is assembled on the first housing 11.
The third through hole 130 penetrates through the wall of the second accommodating cavity 11b, and the contrast cavity 302 and the second accommodating cavity 11b are communicated through the third through hole 130. Preferably, the comparison chamber 302 is disposed on the wall of the second housing chamber 11b adjacent to the first housing chamber 11a, and the third through hole 130 penetrates the wall of the second housing chamber 11b adjacent to the first housing chamber 11a to connect the comparison chamber 302 and the second housing chamber 11b. The fourth through hole 140 penetrates the first housing 11 to communicate with the first accommodating cavity 11a, and the fourth through hole 140 is not communicated with the standard cavity 301 and the comparison cavity 302.
Preferably, the shapes of the first through hole 110, the second through hole 120, the third through hole 130, and the fourth through hole 140 may be circular, rectangular, polygonal, and the like, without particular limitation. The first through hole 110 and the second through hole 120 penetrate the second housing 12 at an interval, and the axial lines of the first through hole 110 and the second through hole 120 are substantially parallel and arranged at an interval. The third through hole 130 and the fourth through hole 140 penetrate the wall of the first accommodating cavity 11a at intervals and communicate with the first accommodating cavity 11a, and the axial leads of the third through hole 130 and the fourth through hole 140 are substantially parallel and arranged at intervals. Of course, in some embodiments, the axes of the first through hole 110, the second through hole 120, the third through hole 130, and the fourth through hole 140 are substantially parallel. It is to be understood that the use of the term "substantially" in this application in terms of a numerical quantity or other quantifiable relationship (e.g., perpendicularity or parallelism) is to be understood as indicating a quantity of ± 10%. Thus, for example, lines that are substantially parallel to each other may be at an angle of between 0 ° and 10 ° to each other.
It is noted that the terms "first", "second", etc. are used herein for descriptive purposes only and are not to be construed as indicating or implying relative importance or implying any number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of the described features.
Referring to fig. 4 and 5, fig. 4 isbase:Sub>A schematic structural view ofbase:Sub>A fence component 30 in some embodiments of the present application, and fig. 5 isbase:Sub>A schematic structural view ofbase:Sub>A cross-section of the fence component 30 alongbase:Sub>A directionbase:Sub>A-base:Sub>A in the embodiment of fig. 4. The enclosure assembly 30 generally includes a first wall 30a and a second wall 30b, the first wall 30a abuts against two opposite sides of the chamber 101 to form a standard chamber 301, the second wall 30b abuts against the two opposite sides of the chamber 101 to form a reference chamber 302, and the liquids in the standard chamber 301 and the reference chamber 302 are not communicated with each other.
Specifically, opposite sides of the first surrounding wall 30a respectively interfere with the first and second cases 11 and 12 to form the standard cavity 301, and opposite sides of the second surrounding wall 30b respectively interfere with the first and second cases 11 and 12 to form the reference cavity 302. The first pipe 310 and the second pipe 320 are provided on the peripheral side of the first enclosure wall 30 a. Preferably, the first duct 310 and the second duct 320 are provided at a side of the first surrounding wall 30a abutting against the second housing 12.
Wherein, the first pipe 310 and the second pipe 320 are disposed at two ends of the first surrounding wall 30a, and both communicate with the standard chamber 301, and both do not communicate with the reference chamber 302. The first surrounding wall 30a and the second surrounding wall 30b are provided between the first housing 11 and the second housing 12, that is, the first housing 11 and the second housing 12 cooperatively sandwich the first surrounding wall 30a and the second surrounding wall 30b. The first surrounding wall 30a and the second surrounding wall 30b may be fixedly connected to the first housing 11 and/or the second housing 12 by screwing, plugging, snapping, welding, adhering, or the like.
The first wall 30a is substantially annular and surrounds the first set of test electrodes 51 such that the first set of test electrodes 51 is exposed to the reference chamber 301. The second wall 30b is generally annular and surrounds the second set of test electrodes 52 such that the second set of test electrodes 52 is exposed to the control chamber 302.
The first duct 310 and the second duct 320 are disposed on the same side of the first surrounding wall 30a and penetrate the second housing 12, respectively. Wherein, the first pipe 310 is embedded in the first through hole 110 and is in interference fit with the inner wall of the first through hole 110 to realize sealing; the second pipe 320 is inserted into the second through hole 120 and is in interference fit with the inner wall of the second through hole 120 to achieve sealing.
In one embodiment, the wall elements 30 can be made of rubber, silicone, or other materials with certain elasticity. For example, the enclosure assembly 30 is made of silicon, and the first enclosure wall 30a, the second enclosure wall 30b, the first pipe 310 and the second pipe 320 may be formed by an integral molding process (e.g., injection molding). Of course, in other embodiments, the first enclosure wall 30a, the second enclosure wall 30b, the first conduit 310, and the second conduit 320 may be assembled into the enclosure assembly 30 after being individually molded, which is not specifically described.
Preferably, the enclosure assembly 30 made of rubber, silicon gel or other materials with certain elasticity may facilitate the first housing 11 and the second housing 12 to seal the standard cavity 301 and the control cavity 302 respectively in an interference fit manner when the enclosure assembly 30 is clamped.
In one embodiment, the first pipe 310 is formed with a liquid inlet hole 311, the second pipe 320 is formed with a liquid outlet hole 321, and the liquid inlet hole 311 and the liquid outlet hole 321 are respectively communicated with the standard chamber 301. Wherein, feed liquor hole 311 roughly includes first feed liquor hole section 3111 and second feed liquor hole section 3112 that are linked together, first feed liquor hole section 3111 and standard chamber 301 intercommunication, and first feed liquor hole section 3111 is located the tip that deviates from standard chamber 301 in first feed liquor hole section 3111 to second feed liquor hole section 3112. The liquid outlet 321 generally comprises a first liquid outlet section 3211 and a second liquid outlet section 3212 which are communicated with each other, the first liquid outlet section 3211 is communicated with the standard cavity 301, and the second liquid outlet section 3212 is arranged at an end of the first liquid outlet section 3211 which deviates from the standard cavity 301. Preferably, the aperture of the first inlet section 3111 is substantially uniform along the axis thereof, and the aperture of the second inlet section 3112 along the axis thereof is gradually increased along the direction away from the first inlet section 3111, that is, the second inlet section 3112 is substantially horn-shaped. The first liquid outlet hole section 3211 has a substantially uniform aperture along the axial direction thereof, and the second liquid outlet hole section 3212 has a gradually increasing aperture along the axial direction thereof in a direction away from the first liquid outlet hole section 3211, that is, the second liquid outlet hole section 3212 is substantially trumpet-shaped. It can be appreciated that the flared second inlet segment 3112 facilitates docking with an external fluid conduit, and the flared second outlet segment 3212 facilitates docking with an external fluid conduit.
Referring to fig. 6, fig. 6 is a schematic structural diagram of the first housing 11 according to some embodiments of the present disclosure. The enclosure assembly 30 generally comprises a first wall 30a and a second wall 30b, the first wall 30a abutting opposite sides of the chamber 101 to form a standard chamber 301, and the second wall 30b abutting the opposite sides of the chamber 101 to form a reference chamber 302. At least one of two opposite surfaces of the cavity 101 has a limiting member 150, and the enclosure assembly 30 is sleeved on the limiting member 150 to limit the enclosure assembly 30.
For example, the limiting member 150 is disposed on the cavity wall of the first accommodating cavity 11a, the limiting member 150 may be a plurality of limiting posts protruding on the cavity wall of the first accommodating cavity 11a, and the first wall 30a and the second wall 30b are sleeved on the plurality of limiting posts to achieve limiting. Of course, in other embodiments, the limiting member 150 may be a limiting wall surrounding the standard chamber 301 and the reference chamber 302, the limiting wall cooperates with the chamber wall of the first receiving chamber 11a to form a limiting groove, and the first wall 30a and the second wall 30b are embedded in the limiting groove to achieve limiting.
Referring to fig. 7 and 8, fig. 7 is a cross-sectional view of a blood sample analysis module 100 according to some embodiments of the present application, and fig. 8 is a structural view of a first housing 11 according to other embodiments of the present application. The enclosure assembly 30 generally comprises a first wall 30a and a second wall 30b, the first wall 30a abutting opposite sides of the chamber 101 to form a standard chamber 301, and the second wall 30b abutting the opposite sides of the chamber 101 to form a reference chamber 302. At least one of two opposite surfaces of the cavity 101 is provided with a first receiving groove 1011 for limiting the first surrounding wall 30a and a second receiving groove 1012 for limiting the second surrounding wall 30b. The first surrounding wall 30a is at least partially embedded in the first receiving groove 1011, and the second surrounding wall 30b is at least partially embedded in the second receiving groove 1012, so as to avoid the dislocation phenomenon of the surrounding wall assembly 30 during assembly.
It should be understood that, by embedding the first surrounding wall 30a and the second surrounding wall 30b in the first receiving groove 1011 and the second receiving groove 1012, respectively, the wall assembly 30 can be prevented from being misaligned, and the tightness of the standard chamber 301 and the reference chamber 302 can be improved, so as to prevent liquid leakage. The shape of the first receiving groove 1011 is adapted to the outer periphery of the first surrounding wall 30a, and the shape of the second receiving groove 1012 is adapted to the outer periphery of the second surrounding wall 30b.
In an embodiment, the first wall 30a and the second wall 30b are an integral structure, and at this time, the first receiving groove 1011 and the second receiving groove 1012 are communicated. Of course, in other embodiments, the first surrounding wall 30a and the second surrounding wall 30b may be separate structures, and in this case, the first receiving groove 1011 and the second receiving groove 1012 are not communicated with each other.
The first pipe 310 and the second pipe 320 are disposed on a side of the first surrounding wall 30a away from the first receiving groove 1011, and are respectively communicated with the first receiving groove 1011, so that the first pipe 310 and the second pipe 320 can be communicated with the standard cavity 301 via the first receiving groove 1011.
Specifically, the bottom wall of the first receiving cavity 1011 is provided with a first fluid channel 1011a communicating with the liquid inlet 311 and a second fluid channel 1011b communicating with the liquid outlet 321, the first fluid channel 1011a communicates with the liquid inlet 311 and the standard cavity 301, respectively, and the second fluid channel 1011b communicates with the liquid outlet 321 and the standard cavity 301, respectively. In other words, the liquid inlet 311 may be communicated with the standard chamber 301 through the first fluid channel 1011a, and the liquid outlet 321 may be communicated with the standard chamber 301 through the second fluid channel 1011 b. That is, the first pipe 310 may communicate with the standard chamber 301 through the first fluid slot 1011a, and the second pipe 320 may communicate with the standard chamber 301 through the second fluid slot 1011 b.
The first enclosure wall 30a and the second enclosure wall 30b are disposed side by side on the wall of the first housing cavity 11 a. When the first shell 11 and the second shell 12 are matched and clamped with the first surrounding wall 30a and the second surrounding wall 30b, the first shell 11 and the second shell 12 are matched and clamped with the first surrounding wall 30a, so that two opposite surfaces of the first surrounding wall 30a are respectively in interference fit with the first shell 11 and the second shell 12 to achieve a sealing effect; the first housing 11 and the second housing 12 cooperate to clamp the second surrounding wall 30b, so that the two opposite surfaces of the second surrounding wall 30b are in interference fit with the first housing 11 and the second housing 12 respectively to achieve a sealing effect.
Meanwhile, the first pipe 310 and the standard cavity 301 are respectively communicated with the first fluid groove 1011a, and the second pipe 320 and the standard cavity 301 are respectively communicated with the second fluid groove 1011b, so that the liquid outside the blood sample analysis module 100 can flow into the first fluid groove 1011a through the first pipe 310 and then flow into the standard cavity 301 through the first fluid groove 1011 a; and the liquid in the standard chamber 301 can flow into the second pipe 320 through the second fluid groove 1011b and then flow to the outside of the blood sample analysis module 100 through the second pipe 320.
As described above, the third through hole 130 penetrates the wall of the second receiving cavity 11b. Further, the third through hole 130 penetrates through the bottom wall of the second receiving groove 1012, so that the contrast chamber 302 can be communicated with the second receiving chamber 11b through the third through hole 130. That is, the liquid in the second receiving chamber 11b can flow into the contrast chamber 302 through the third through hole 130. Preferably, the second wall 30b is disposed around the periphery of the third through hole 130 to improve the sealing effect of the control chamber 302.
It can be understood that when the blood sample analysis module 100 is used with a blood gas analysis device, the liquids such as the test solution, the calibration solution, and the cleaning solution can flow through the standard chamber 301 to perform the corresponding testing, calibration, and cleaning operations. It is understood that at least one electrode for performing electrochemical analysis may be disposed on the second housing 12, the electrode may be distributed on the walls of the standard chamber 301 and the control chamber 302, and the liquid flowing into the standard chamber 301 and the control chamber 302 covers the electrode, so that PH, hematocrit, ion concentration, lactic acid, and O can be realized by the electric signal on the electrode 2 、CO 2 Partial pressure and the like.
The application provides a blood sample analysis module, before testing liquid measurement, washing liquid and calibration liquid flow in the standard chamber respectively and accomplish washing and calibration operation to from the standard chamber class sample analysis module that flows out after the operation is accomplished, can not store inside the blood sample analysis module. The test solution flows into the standard cavity to complete parameter measurement, and flows out of the blood sample analysis module from the standard cavity after the measurement is completed, so that the test solution cannot be stored in the blood sample analysis module. The application provides a blood sample analysis module need not to set up the waste liquid recovery container in blood sample analysis module inside, can greatly reduce the volume of blood sample analysis module, does benefit to the frivolousization that realizes blood sample analysis module. In addition, test solution, washing liquid and calibration liquid flow through the standard chamber respectively in order to accomplish corresponding operation, then flow out blood sample analysis module from the standard chamber for blood sample analysis module can realize repetitious measurements many times, has greatly improved the measurement number of times of blood sample analysis module, need not frequently to change blood sample analysis module, can further promote efficiency of software testing.
Referring to fig. 9, fig. 9 is a partial structural schematic view of a blood sample analysis module 100 according to some embodiments of the present application, wherein fig. 9 illustrates a manner in which a wall assembly 30 is engaged with a second housing 12. The first enclosure wall 30a and the second enclosure wall 30b of the enclosure assembly 30 are disposed side by side on the second housing 12, and cooperate with the second housing 12 and the first housing 11 to form a reference chamber 302 of the standard chamber 301. As mentioned above, the second casing 12 may be a circuit board on which the first testing electrode set 51, the second testing electrode set 52 and the third testing electrode set 53 are disposed at intervals.
Wherein the first test electrode group 51 is configured to measure an electrochemical parameter of the liquid in the standard chamber 301, and the second test electrode group 52 is configured to obtain an electrode potential to ensure that the potential of the first test electrode group 51 is stable.
In particular, the first set of test electrodes 51 may comprise at least one test electrode exposed on a wall of the standard chamber 301 for acquiring electrochemical parameters of the liquid in the standard chamber 301. The second test electrode set 52 can include at least one reference electrode exposed on the walls of the control chamber 302 for acquiring electrode potentials. The first test electrode group 51 and the second test electrode group 52 are respectively connected to the third test electrode group 53, so that the acquired signal data are sent to the blood gas analysis equipment for further processing through the third test electrode group 53.
Based on this, the control cavity 302 is configured to contain liquid such as reference liquid, and no additional container for containing liquid such as reference liquid is needed, so that the whole structure is simple, and the assembly is convenient. Wherein, a salt bridge 54 penetrating through the standard cavity 301 and the comparison cavity 302 is further arranged on the second shell 12 to reduce the hydraulic connection potential. It can be understood that a salt bridge is inserted between the two solutions to replace the original direct contact of the two solutions, so as to reduce or stabilize the liquid junction potential (when two electrolytes with different compositions or activities are contacted, a double electric layer is formed at a solution junction due to the fact that positive and negative ions are separated through the difference of ion migration speeds of the interface in a diffusion mode, so that the generated potential difference is called the liquid junction diffusion potential, namely the liquid junction potential), and the liquid junction potential is reduced to the minimum to be close to the elimination. I.e. to prevent ions in the standard chamber 301 from diffusing into the control chamber 302 and affecting the potential of the reference electrode. For example, when the reference solution in the control chamber 302 is a saturated KCI solution, the concentration is generally as high as 4.2mol/dm 3 When the salt bridge is inserted into the interface between two electrolyte solutions of low concentration, two interfaces are created, and the outward diffusion of K + and CI-in the salt bridge becomes the main stream of ion diffusion at these two interfaces. Because the diffusion rates of K + and CI-are similar, the liquid-contact potential generated by the contact of the salt bridge and two solutions is very small, and the directions of the K + and the CI-are opposite, so that the K + and the CI-are mutually counteracted and then reduced to 1-2 mV. The principle of choosing the electrolyte in the salt bridge is high concentration, nearly equal transport numbers of positive and negative ions, and no chemical reaction with the liquid in the standard chamber 301. The reference solution is usually a saturated solution of KCI, NH4NO3 and KNO 3.
Namely, the salt bridge 54 is arranged to penetrate through the standard cavity 301 and the control cavity 302 so as to ensure that the liquid in the standard cavity 301 and the liquid in the control cavity 302 are not mixed, and the potential influence on the reference electrode is reduced.
It will be appreciated that the second receiving cavity 11b is configured to receive the reference solution or a container containing the reference solution, and the reference solution in the second receiving cavity 11b can flow into the control cavity 302 through the third through hole 130, so as to increase the number of times the blood sample analysis module is used.
The application provides a blood sample analysis module, through set up the enclosure subassembly in order to form standard chamber and contrast chamber in the cavity in the casing, and through first pipeline and the second pipeline that sets up intercommunication standard chamber on the enclosure subassembly, the first through-hole of first pipeline embedding casing, the second through-hole of second pipeline embedding casing, in order to communicate the casing inside and outside, make the outside liquid of blood sample analysis module can flow in from first pipeline and second pipeline and flow out standard chamber, and the liquid of holding in advance in outside liquid or the blood sample analysis module can flow in contrast chamber from the third through-hole. Meanwhile, the cavity walls of the standard cavity and the contrast cavity are provided with electrode assemblies, so that the blood sample analysis module can complete corresponding measurement operation, liquid in the standard cavity after measurement is completed cannot be stored in the blood sample analysis module, and the volume of the blood sample analysis module can be greatly reduced. Liquid in the standard cavity can flow in and flow out blood sample analysis module through first pipeline and second pipeline respectively for blood sample analysis module can realize the repeated measurement many times, has greatly improved the measuring number of times of blood sample analysis module, need not frequently to change blood sample analysis module, and efficiency of software testing is high.
It is noted that the terms "comprises" and "comprising," as well as any variations thereof, are intended to cover non-exclusive inclusions. For example, a process, method, system, article, or apparatus that comprises a list of steps or elements is not limited to only those steps or elements listed, but may alternatively include other steps or elements not listed, or inherent to such process, method, article, or apparatus.
The above description is only a part of the embodiments of the present application, and not intended to limit the scope of the present application, and all equivalent devices or equivalent processes performed by the content of the present application and the attached drawings, or directly or indirectly applied to other related technical fields, are also included in the scope of the present application.
Claims (13)
1. A blood sample analysis module, comprising:
the shell is internally provided with a cavity and is provided with a first through hole, a second through hole and a third through hole;
the wall assembly is arranged in the cavity and is in contact with the cavity to form a standard cavity and a contrast cavity, the first through hole and the second through hole are communicated with the standard cavity, and the third through hole is communicated with the contrast cavity; the wall of each standard cavity and the wall of each contrast cavity are provided with electrode assemblies;
wherein, the enclosure subassembly the standard chamber and/or week side of contrast chamber is equipped with first pipeline and second pipeline, first pipeline embedding first through-hole, the embedding of second pipeline the second through-hole, just first pipeline with the second pipeline all communicates the standard chamber.
2. The blood sample analysis module of claim 1, wherein the enclosure assembly comprises a first enclosure wall and a second enclosure wall, the first enclosure wall abutting opposite sides of the chamber body to form the standard chamber, the second enclosure wall abutting opposite sides of the chamber body to form the control chamber, and the standard chamber and the control chamber are not in fluid communication with each other.
3. The blood sample analysis module of claim 2, wherein a retaining member is disposed on a wall of at least one of the opposing sides, and the enclosure assembly is disposed around the retaining member.
4. The module of claim 2, wherein a wall of one of the opposing surfaces defines a first receiving cavity for receiving the first wall and a second receiving cavity for receiving the second wall, the first wall being at least partially embedded in the first receiving cavity, and the second wall being at least partially embedded in the second receiving cavity.
5. The blood sample analysis module of claim 4 wherein the first enclosure wall and the second enclosure wall are of unitary construction.
6. The blood sample analysis module of claim 4, wherein the first receiving cavity is in communication with the second receiving cavity.
7. The module of claim 4, wherein the first conduit and the second conduit are disposed on a side of the first wall facing away from the first receiving chamber and are respectively connected to the first receiving chamber.
8. The module of claim 7, wherein the bottom wall of the first receiving chamber defines a first fluid channel and a second fluid channel, the first conduit communicates with the standard chamber via the first fluid channel, and the second conduit communicates with the standard chamber via the second fluid channel.
9. The blood sample analysis module of claim 1, wherein the housing comprises a first housing and a second housing disposed on one side of the first housing, and a first receiving cavity and a second receiving cavity are disposed on opposite sides of the first housing; the second shell is at least partially embedded in the first accommodating cavity and is matched with the first shell to enclose the first accommodating cavity to form the cavity.
10. The blood sample analysis module of claim 9, wherein the first and second through-holes each extend through the second housing to communicate with the standard chamber.
11. The blood sample analysis module of claim 9, wherein the third aperture extends through a wall of the second receiving chamber, and the control chamber and the second receiving chamber are in communication via the third aperture.
12. The blood sample analysis module of claim 9, wherein the second housing is a circuit board, and the electrode assembly includes a first set of test electrodes and a second set of test electrodes disposed on the circuit board, the first set of test electrodes being exposed in the standard chamber and the second set of test electrodes being exposed in the control chamber.
13. The blood sample analysis module of claim 12, wherein the electrode assembly further comprises a third testing electrode set disposed on the circuit board, the first housing defines a fourth through hole in communication with the first receiving cavity, and the third testing electrode set is exposed to the exterior of the blood sample analysis module through the fourth through hole.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202221116990.1U CN217879016U (en) | 2022-05-09 | 2022-05-09 | Blood sample analysis module |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202221116990.1U CN217879016U (en) | 2022-05-09 | 2022-05-09 | Blood sample analysis module |
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| Publication Number | Publication Date |
|---|---|
| CN217879016U true CN217879016U (en) | 2022-11-22 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN202221116990.1U Active CN217879016U (en) | 2022-05-09 | 2022-05-09 | Blood sample analysis module |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024027668A1 (en) * | 2022-07-31 | 2024-02-08 | 深圳市理邦精密仪器股份有限公司 | Sample test card |
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2022
- 2022-05-09 CN CN202221116990.1U patent/CN217879016U/en active Active
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024027668A1 (en) * | 2022-07-31 | 2024-02-08 | 深圳市理邦精密仪器股份有限公司 | Sample test card |
| WO2024027667A1 (en) * | 2022-07-31 | 2024-02-08 | 深圳市理邦精密仪器股份有限公司 | Detection assembly for medical detection equipment, and medical detection equipment |
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