CN217838984U - Glutathione reductase detection kit - Google Patents
Glutathione reductase detection kit Download PDFInfo
- Publication number
- CN217838984U CN217838984U CN202221404218.XU CN202221404218U CN217838984U CN 217838984 U CN217838984 U CN 217838984U CN 202221404218 U CN202221404218 U CN 202221404218U CN 217838984 U CN217838984 U CN 217838984U
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- Prior art keywords
- glutathione reductase
- box
- test tube
- water bath
- box body
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- 108010063907 Glutathione Reductase Proteins 0.000 title claims abstract description 40
- 102100036442 Glutathione reductase, mitochondrial Human genes 0.000 title claims abstract description 40
- 238000001514 detection method Methods 0.000 title claims description 39
- 238000006243 chemical reaction Methods 0.000 claims abstract description 45
- 238000012360 testing method Methods 0.000 claims abstract description 34
- 230000007246 mechanism Effects 0.000 claims abstract description 24
- 238000010438 heat treatment Methods 0.000 claims abstract description 22
- 239000000463 material Substances 0.000 claims abstract description 20
- 239000003153 chemical reaction reagent Substances 0.000 claims abstract description 14
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 50
- 238000001816 cooling Methods 0.000 claims description 18
- 239000002826 coolant Substances 0.000 claims description 16
- 238000009434 installation Methods 0.000 claims description 11
- 235000017166 Bambusa arundinacea Nutrition 0.000 claims description 9
- 235000017491 Bambusa tulda Nutrition 0.000 claims description 9
- 241001330002 Bambuseae Species 0.000 claims description 9
- 235000015334 Phyllostachys viridis Nutrition 0.000 claims description 9
- 239000011425 bamboo Substances 0.000 claims description 9
- 238000003149 assay kit Methods 0.000 claims description 7
- 238000010521 absorption reaction Methods 0.000 claims description 6
- 238000009413 insulation Methods 0.000 claims description 5
- 230000005389 magnetism Effects 0.000 claims description 3
- 230000006872 improvement Effects 0.000 abstract description 4
- 230000004044 response Effects 0.000 description 5
- 230000009471 action Effects 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 108010024636 Glutathione Proteins 0.000 description 2
- 108010053070 Glutathione Disulfide Proteins 0.000 description 2
- ACFIXJIJDZMPPO-NNYOXOHSSA-N NADPH Chemical compound C1=CCC(C(=O)N)=CN1[C@H]1[C@H](O)[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]2[C@H]([C@@H](OP(O)(O)=O)[C@@H](O2)N2C3=NC=NC(N)=C3N=C2)O)O1 ACFIXJIJDZMPPO-NNYOXOHSSA-N 0.000 description 2
- 239000012620 biological material Substances 0.000 description 2
- 239000003085 diluting agent Substances 0.000 description 2
- RWSXRVCMGQZWBV-WDSKDSINSA-N glutathione Chemical compound OC(=O)[C@@H](N)CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O RWSXRVCMGQZWBV-WDSKDSINSA-N 0.000 description 2
- YPZRWBKMTBYPTK-BJDJZHNGSA-N glutathione disulfide Chemical compound OC(=O)[C@@H](N)CCC(=O)N[C@H](C(=O)NCC(O)=O)CSSC[C@@H](C(=O)NCC(O)=O)NC(=O)CC[C@H](N)C(O)=O YPZRWBKMTBYPTK-BJDJZHNGSA-N 0.000 description 2
- 229930027945 nicotinamide-adenine dinucleotide Natural products 0.000 description 2
- YPZRWBKMTBYPTK-UHFFFAOYSA-N oxidized gamma-L-glutamyl-L-cysteinylglycine Natural products OC(=O)C(N)CCC(=O)NC(C(=O)NCC(O)=O)CSSCC(C(=O)NCC(O)=O)NC(=O)CCC(N)C(O)=O YPZRWBKMTBYPTK-UHFFFAOYSA-N 0.000 description 2
- 239000000523 sample Substances 0.000 description 2
- 108010001103 Glutathione oxidase Proteins 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 238000003491 array Methods 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000012472 biological sample Substances 0.000 description 1
- 230000006037 cell lysis Effects 0.000 description 1
- 238000004737 colorimetric analysis Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 150000001451 organic peroxides Chemical class 0.000 description 1
- 125000002081 peroxide group Chemical group 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
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- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The utility model relates to a glutathione reductase detects technical field, and discloses a glutathione reductase detect reagent box, including box, a plurality of rubber head burette of locating the box top, articulate in the chamber door of box one side, locate inside reaction platform, rotary mechanism and the water-bath heating subassembly of box and locate the test tube fixture on the reaction platform, rotary mechanism is used for driving the reaction platform rotates, the water-bath heating subassembly is used for realizing the water-bath heating that glutathione reductase detected, test tube fixture is used for the clamping splendid attire to detect the test tube that biological examined the material, the utility model discloses a test tube fixture can carry out the centre gripping with the test tube of different diameters to make detect reagent box be applicable to the test tube of different diameters, increased detect reagent box's application scope effectively, great improvement detect reagent box's practicality, so that glutathione reductase's high efficiency detects.
Description
Technical Field
The utility model belongs to the technical field of glutathione reductase detects, concretely relates to glutathione reductase detect reagent box.
Background
The glutathione reductase detection kit is a simple and easy kit for detecting the activity of the glutathione reductase in cells, tissues or other samples by ultraviolet colorimetry. Glutathione reductase is distributed in many tissues and can maintain sufficient levels of reduced glutathione in the cell. To scavenge free radicals or some organic peroxides, glutathione reductase assay kits are typically used to perform assays in which reduced glutathione may, or may serve as a substrate for glutathione oxidase, scavenge glutathione reductase activity in some peroxide cells, tissues or other samples.
In the chinese patent with patent No. 201822128358.9, a glutathione reductase detection kit is mentioned, which can detect the activity of glutathione reductase in biological samples such as tissue homogenate products, cell lysis products and the like, one kit can carry out multiple detections, the operation is simple, and biological detection materials and reagents required by the detection of glutathione reductase can be transported and stored simultaneously, but the detection kit can not clamp test tubes with different diameters, so that the detection kit can not be suitable for the test tubes with different diameters, the efficient detection of glutathione reductase is inconvenient, in addition, the disassembly and assembly of a reaction table are complicated, the quick disassembly and assembly of the reaction table can not be realized, the efficient detection of the biological detection materials is inconvenient, and the detection cost is increased.
SUMMERY OF THE UTILITY MODEL
An object of the utility model is to provide a glutathione reductase detect reagent box to the test tube that can not be with different diameters that proposes in solving above-mentioned background art carries out the centre gripping, leads to detect reagent box can not be applicable to the test tube of different diameters, can not realize the quick assembly disassembly of reaction platform in addition, and the biology of being not convenient for is examined the high efficiency of material and is detected, has increased the problem that detects the cost.
In order to achieve the above purpose, the utility model provides a following technical scheme: the utility model provides a glutathione reductase detect reagent box, includes box, a plurality of rubber head burette of locating the box top, articulates in the chamber door of box one side, locates inside reaction platform, rotary mechanism and the water bath heating subassembly of box and locate the test tube fixture on the reaction platform, rotary mechanism is used for driving the reaction platform rotates, the water bath heating subassembly is used for realizing the water bath heating that glutathione reductase detected, test tube fixture is used for the clamping splendid attire to wait to detect the test tube of biological material, and test tube fixture includes that a plurality of annular arrays of being install in the installation section of thick bamboo on reaction platform top, and a plurality of installation sections of thick bamboo and a plurality of rubber head burette one-to-one, and is a plurality of springs that are annular array and distribute are all installed to the inside of installation section of thick bamboo, and the one end of a plurality of springs all is connected with the grip block.
Preferably, the inside of box still is equipped with cooling unit and heat insulating board, and cooling unit and heat insulating board are located between rotary mechanism and the water bath heating unit from top to bottom in proper order.
Preferably, the rotating mechanism comprises a cam divider and a support frame which are arranged inside the box body, and a rotating rod horizontally screwed on one side of the box body, a connecting shaft is arranged at the top end of the cam divider, one side of the cam divider is movably connected with the end part of the rotating rod, a hand wheel is arranged at one end of the rotating rod, which is positioned outside the box body, and the rotating rod penetrates through the support frame.
Preferably, the water bath heating assembly comprises a water bath cavity arranged below the inside of the box body, a second temperature sensor arranged on one side of the inner wall of the water bath cavity, and a water inlet pipe and a water outlet pipe which are fixed on two sides of the box body, wherein the water inlet pipe and the water outlet pipe are communicated with the water bath cavity.
Preferably, the cooling assembly comprises a cooling cavity, a first temperature sensor fixed on one side of the inner wall of the box body, and a cooling medium inlet and a cooling medium outlet which are arranged on two sides of the box body, and the cooling medium inlet and the cooling medium outlet are communicated with the cooling cavity.
Preferably, still include the absorption fixed establishment who is connected reaction table and rotary mechanism, absorption fixed establishment is including installing in the connecting cylinder of reaction table bottom, seting up in the inside axial trough of connecting cylinder, seting up in the inside recess of axial trough and be fixed in the projection on connecting axle top, the projection inserts in the recess, and the top of projection installs first magnetic path, the inside of recess is fixed with the second magnetic path opposite with first magnetic path magnetism.
Preferably, adsorb fixed establishment still includes spacing subassembly, spacing subassembly includes that a plurality of stopper that are the annular array and install in the shaft groove inner wall and a plurality of spacing groove of seting up in the connecting axle outer wall, and is a plurality of spacing groove and a plurality of stopper one-to-one.
Compared with the prior art, the beneficial effects of the utility model are that:
(1) The utility model discloses a test tube fixture can carry out the centre gripping with the test tube of different diameters to make detect reagent box be applicable to the test tube of different diameters, increased detect reagent box's application scope effectively, great improvement detect reagent box's practicality, so that glutathione reductase's high efficiency detects.
(2) The utility model discloses an adsorb fixed establishment and simplified the dismouting step of reaction bench, can realize the quick assembly disassembly of reaction bench, improved the dismouting efficiency of reaction bench effectively to in the biological detection of examining the material, great improvement biological detection efficiency of examining the material, can further realize the high-efficient of glutathione reductase and detect, sparingly detect the cost.
Drawings
FIG. 1 is a schematic view of the present invention;
fig. 2 is a front view of the present invention;
FIG. 3 is a top view of the reaction table of the present invention;
FIG. 4 is a bottom view of the reaction table of the present invention;
fig. 5 is a top view of the connecting shaft of the present invention;
FIG. 6 is an enlarged view taken at A in FIG. 3;
FIG. 7 is an enlarged view of FIG. 3 at B;
in the figure: 1. a box body; 2. a rubber head dropper; 3. a box door; 4. a heat insulation plate; 5. a cooling assembly; 51. a cooling medium inlet; 52. a cooling chamber; 53. a first temperature sensor; 54. a cooling medium outlet; 6. a rotation mechanism; 61. a hand wheel; 62. a support frame; 63. a rotating rod; 64. a cam divider; 65. a connecting shaft; 7. a water bath heating assembly; 71. a water bath cavity; 72. a water inlet pipe; 73. a second temperature sensor; 74. a water outlet pipe; 8. an adsorption fixing mechanism; 81. a connecting cylinder; 82. a shaft groove; 83. a limiting block; 84. a convex column; 85. a first magnetic block; 86. a limiting groove; 87. a groove; 88. a second magnetic block; 9. a reaction platform; 10. a test tube clamping mechanism; 101. mounting the cylinder; 102. a spring; 103. and (4) clamping the plate.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative efforts all belong to the protection scope of the present invention.
Referring to fig. 1-7, the present invention provides the following technical solutions: a glutathione reductase detection kit comprises a box body 1, a plurality of rubber dropper 2 embedded at the top of the box body 1, a box door 3 hinged at one side of the box body 1, a reaction table 9 arranged inside the box body 1, a rotating mechanism 6, a water bath heating component 7 and a test tube clamping mechanism 10 arranged on the reaction table 9;
the rotating mechanism 6 is used for driving the reaction table 9 to rotate, the rotating mechanism 6 comprises a cam divider 64 and a support frame 62 which are arranged inside the box body 1, and a rotating rod 63 which is horizontally screwed on one side of the box body 1, a connecting shaft 65 is arranged at the top end of the cam divider 64, one side of the cam divider 64 is movably connected with the end part of the rotating rod 63, a hand wheel 61 is arranged at one end of the rotating rod 63 which is positioned outside the box body 1, and the rotating rod 63 penetrates through the support frame 62;
the water bath heating assembly 7 is used for realizing water bath heating of glutathione reductase detection, the water bath heating assembly 7 comprises a water bath cavity 71 arranged below the inner part of the box body 1, a second temperature sensor 73 arranged on one side of the inner wall of the water bath cavity 71, and a water inlet pipe 72 and a water outlet pipe 74 which are fixed on two sides of the box body 1, and the water inlet pipe 72 and the water outlet pipe 74 are both communicated with the water bath cavity 71;
As shown in fig. 1 to 3, four rubber dropper tubes 2 and four mounting cylinders 101 are provided; when the biological detection material is used for detecting glutathione reductase, a detector can firstly suck the glutathione reductase, oxidized glutathione, NADPH and a sample diluent solution in a quantitative mode one by four rubber-headed droppers 2, sequentially install the four rubber-headed droppers 2 at the top of a box body 1, sequentially install four test tubes with the biological detection material in four installation cylinders 101 on a reaction table 9, then open a box door 3, install the reaction table 9 on a rotating mechanism 6, close the box door 3, rotate a rotating rod 63 through a hand wheel 61, drive the reaction table 9 to rotate under the action of a cam divider 64 and a connecting shaft 65 so as to drive the four installation cylinders 101 on the reaction table 9 to rotate intermittently, and simultaneously, the detector gradually pinches the four rubber-headed droppers 2 so that the glutathione reductase, the oxidized glutathione, the NADPH and the sample diluent solution in the four rubber-headed droppers 2 are gradually and quantitatively dripped into the test tubes with the biological detection material, so as to detect the glutathione reductase for the biological detection material;
after the detection of the glutathione reductase is completed, a detector can open the box door 3, disassemble the reaction platform 9, put the reaction platform 9 into the water bath cavity 71, close the box door 3, add water into the water bath cavity 71 through the water inlet pipe 72 to heat the biological detection material on the reaction platform 9 in a water bath, and simultaneously, the second temperature sensor 73 detects the temperature in the water bath cavity 71 in real time and displays the temperature through the display screen on the box door 3, so that the detection of the glutathione reductase is realized;
in addition, as shown in fig. 3 and fig. 6, each mounting cylinder 101 is provided with four clamping plates 103 and springs 102, when a tester inserts a test tube containing biological detection materials into the mounting cylinder 101, the four clamping plates 103 inside the mounting cylinder 101 elastically clamp the test tube under the action of the springs 102, and the clamping plates 103 can clamp the test tubes with different diameters under the elastic action of the springs 102, so that the detection kit is suitable for the test tubes with different diameters, the application range of the detection kit is effectively increased, the practicability of the detection kit is greatly improved, and the efficient detection of glutathione reductase is facilitated.
Furthermore, a cooling assembly 5 and a heat insulation plate 4 are arranged inside the box body 1, and the cooling assembly 5 and the heat insulation plate 4 are sequentially positioned between the rotating mechanism 6 and the water bath heating assembly 7 from top to bottom;
the cooling assembly 5 comprises a cooling cavity 52, a first temperature sensor 53 fixed on one side of the inner wall of the box body 1, and a cooling medium inlet 51 and a cooling medium outlet 54 which are arranged on two sides of the box body 1, wherein the cooling medium inlet 51 and the cooling medium outlet 54 are both communicated with the cooling cavity 52.
When the biological detection material is stored after the detection is finished, a detector can input a cooling medium into the cooling cavity 52 through the cooling medium inlet 51 to cool the interior of the box body 1, and meanwhile, the first temperature sensor 53 detects the temperature of the interior of the box body 1 in real time and displays the temperature through the display screen on the box door 3 to ensure that the biological detection material on the reaction table 9 is stored in a proper environment;
in addition, the thermal-insulated layer 4 can insulate heat between the reaction platform 9 and the water bath heating assembly 7, so that the storage environment of the biological detection material on the reaction platform 9 is prevented from being influenced by the water bath heating assembly 7, and the storage of the biological detection material is further ensured.
Further, still include the absorption fixed establishment 8 of being connected reaction platform 9 and rotary mechanism 6, absorption fixed establishment 8 is including installing at the connecting cylinder 81 of reaction platform 9 bottom, seting up in the inside shaft slot 82 of connecting cylinder 81, seting up in the inside recess 87 of shaft slot 82, and be fixed in the projection 84 at connecting axle 65 top, in projection 84 inserts recess 87, and the top of projection 84 installs first magnetic block 85, and the inside of recess 87 is fixed with the second magnetic block 88 opposite with first magnetic block 85 magnetism.
When a detector installs the reaction table 9 on the rotating mechanism 6, the reaction table 9 can be sleeved on the top end of the connecting shaft 65 through the connecting cylinder 81 at the bottom of the reaction table 9, so that the top of the connecting shaft 65 is inserted into the shaft groove 82 until the convex column 84 is inserted into the groove 87, then the first magnetic block 85 is contacted with the second magnetic block 88, and the connecting shaft 65 and the connecting shaft 81 are magnetically attracted under the principle that like magnetic poles repel each other and opposite magnetic poles attract each other, so that the reaction table 9 and the rotating mechanism 6 are adsorbed and fixed, and then biological detection materials on the reaction table 9 are detected;
after detecting the completion, the testing personnel can upwards stimulate the response platform 9, make first magnetic path 85 and the separation of second magnetic path 88, separate until connecting cylinder 81 and connecting axle 65, in order to dismantle response platform 9, then the testing personnel put into water bath chamber 71 with response platform 9 and carry out the water bath heating, thereby realize the quick assembly disassembly of response platform 9, the dismouting efficiency of response platform 9 has been improved effectively, in order to examine the detection of material biologically, great improvement the detection efficiency of material is examined to biology, can further realize the high-efficient detection of glutathione reductase, save the detection cost.
Further, adsorb fixed establishment 8 and still include spacing subassembly, spacing subassembly includes a plurality of stopper 83 that are the annular array and install in axle slot 82 inner wall, and a plurality of spacing groove 86 of seting up in connecting axle 65 outer wall, a plurality of spacing groove 86 and a plurality of stopper 83 one-to-one, when connecting axle 65 injects in axle slot 82, stopper 83 injects into the spacing groove 86 thereupon, with spacing between connecting axle 65 and the axle slot 82, thereby be convenient for stably peg graft between connecting axle 65 and the axle slot 82.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (7)
1. A glutathione reductase detect reagent box, characterized by that: including box (1), a plurality of rubber head burette (2) of locating box (1) top, articulate in box door (3) of box (1) one side, locate inside reaction platform (9), rotary mechanism (6) and water bath heating subassembly (7) of box (1) and locate test tube fixture (10) on reaction platform (9), rotary mechanism (6) are used for driving reaction platform (9) rotate, water bath heating subassembly (7) are used for realizing the water bath heating that glutathione reductase detected, test tube fixture (10) are used for the clamping splendid attire to wait to detect the test tube of biological detection material, and test tube fixture (10) include that a plurality of are annular array and install in installation section of thick bamboo (101) on reaction platform (9) top, and a plurality of installation section of thick bamboo (101) and a plurality of rubber head burette (2) one-to-ones, and a plurality of spring (102) that are the annular array and distribute are all installed to the inside of installation section of thick bamboo (101), and the one end of a plurality of spring (102) all is connected with grip block (103).
2. The glutathione reductase assay kit according to claim 1, wherein: the box body (1) is internally provided with a cooling assembly (5) and a heat insulation plate (4), and the cooling assembly (5) and the heat insulation plate (4) are sequentially arranged between the rotating mechanism (6) and the water bath heating assembly (7) from top to bottom.
3. The glutathione reductase assay kit of claim 1, wherein: the rotating mechanism (6) comprises a cam divider (64) and a support frame (62) which are installed inside the box body (1), and a rotating rod (63) horizontally screwed on one side of the box body (1), a connecting shaft (65) is installed at the top end of the cam divider (64), one side of the cam divider (64) is movably connected with the end portion of the rotating rod (63), a hand wheel (61) is installed at one end, located outside the box body (1), of the rotating rod (63), and the rotating rod (63) penetrates through the support frame (62).
4. The glutathione reductase assay kit according to claim 2, wherein: the water bath heating assembly (7) comprises a water bath cavity (71) arranged below the inside of the box body (1), a second temperature sensor (73) arranged on one side of the inner wall of the water bath cavity (71), and a water inlet pipe (72) and a water outlet pipe (74) fixed on two sides of the box body (1), wherein the water inlet pipe (72) and the water outlet pipe (74) are communicated with the water bath cavity (71).
5. The glutathione reductase assay kit of claim 2, wherein: the cooling assembly (5) comprises a cooling cavity (52), a first temperature sensor (53) fixed on one side of the inner wall of the box body (1), a cooling medium inlet (51) and a cooling medium outlet (54) which are installed on two sides of the box body (1), wherein the cooling medium inlet (51) and the cooling medium outlet (54) are communicated with the cooling cavity (52).
6. The glutathione reductase assay kit of claim 3, wherein: still include absorption fixed establishment (8) of being connected reaction platform (9) and rotary mechanism (6), absorption fixed establishment (8) is including installing in connecting cylinder (81) of reaction platform (9) bottom, offering in inside axle slot (82) of connecting cylinder (81), offering in inside recess (87) of axle slot (82) and being fixed in convex column (84) on connecting axle (65) top, convex column (84) insert in recess (87), and the top of convex column (84) installs first magnetic path (85), the inside of recess (87) is fixed with second magnetic path (88) opposite with first magnetic path (85) magnetism.
7. The glutathione reductase assay kit of claim 6, wherein: adsorb fixed establishment (8) and still include spacing subassembly, spacing subassembly includes a plurality of stopper (83) that are the annular array and install in shaft groove (82) inner wall and a plurality of spacing groove (86) of seting up in connecting axle (65) outer wall, and is a plurality of spacing groove (86) and a plurality of stopper (83) one-to-one.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202221404218.XU CN217838984U (en) | 2022-06-08 | 2022-06-08 | Glutathione reductase detection kit |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202221404218.XU CN217838984U (en) | 2022-06-08 | 2022-06-08 | Glutathione reductase detection kit |
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| Publication Number | Publication Date |
|---|---|
| CN217838984U true CN217838984U (en) | 2022-11-18 |
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ID=84021181
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202221404218.XU Active CN217838984U (en) | 2022-06-08 | 2022-06-08 | Glutathione reductase detection kit |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN217838984U (en) |
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2022
- 2022-06-08 CN CN202221404218.XU patent/CN217838984U/en active Active
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| TR01 | Transfer of patent right |
Effective date of registration: 20231106 Address after: No. 213, Beigushi Village, Nanshahe Town, Tengzhou City, Zaozhuang City, Shandong Province, 277513 Patentee after: Cai Jinbao Address before: Room 216 and 218, Block A, China Russia Science Park Incubation Building, No. 191 Chaoqun Street, Changchun Hi tech Industrial Development Zone, 130000 Jilin Province Patentee before: Jilin Guoke Technology Co.,Ltd. |
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Effective date of registration: 20240103 Address after: 277521, Zone 1-2316, Lunda D, Beixin Road, Beixin Street, Tengzhou City, Zaozhuang City, Shandong Province Patentee after: Shandong Tianming Biotechnology Co.,Ltd. Address before: No. 213, Beigushi Village, Nanshahe Town, Tengzhou City, Zaozhuang City, Shandong Province, 277513 Patentee before: Cai Jinbao |