CN217774975U

CN217774975U - Heparin sodium preparation is with elution device

Info

Publication number: CN217774975U
Application number: CN202221272247.5U
Authority: CN
Inventors: 余兰勇; 余艳
Original assignee: Xinyang Pingqiao Xinyi Casing Technology Co ltd
Current assignee: Xinyang Pingqiao Xinyi Casing Technology Co ltd
Priority date: 2022-05-25
Filing date: 2022-05-25
Publication date: 2022-11-11
Anticipated expiration: 2032-05-25

Abstract

The utility model provides an elution device for heparin sodium preparation, which relates to the technical field of heparin sodium and comprises an elution tank, a water pump and a filter box, wherein the bottom of the elution tank is fixedly connected with a pumping pipe; the utility model discloses fill into the inside in-process of rose box, open the solenoid valve on a shunt tubes and close the solenoid valve on two other shunt tubes, resin in the solution filters through an elution filter screen, the back is through opening the solenoid valve on communicating pipe, the solution after will filtering is discharged again and is added sodium chloride solution once more to elution jar inside, repeated above-mentioned operation is eluted once more, can fully elute the resin and draw the heparin composition that adsorbs wherein after the elution cubic, the device has replaced the mode that uses three elution jar to carry out elution in the past, thereby the area of user equipment has been reduced, and take out through the inside of following the rose box with the elution filter screen, thereby make the device conveniently clear up the advantage of elution filter screen.

Description

Heparin sodium preparation is with elution device

Technical Field

The utility model relates to a heparin sodium technical field specifically is a heparin sodium preparation is with elution device.

Background

Heparin sodium is a mucopolysaccharide sulfate anticoagulant, is sodium salt of glycosaminoglycan extracted from intestinal mucosa of pigs or cattle, belongs to mucopolysaccharide substances, generally needs to be subjected to the process steps of intestine scraping, enzymolysis, adsorption, elution, precipitation and the like in the conventional heparin sodium processing method of a heparin primary product, and in the elution process, the resin after heparin adsorption is usually eluted by saline water in an elution tank.

The three elution processes that come to carry out elution for a set of usually of current elution jar, and the jar body is installed subaerial, and it is great to occupy factory building area, and installs the inconvenient clearance of filter screen in the elution jar.

SUMMERY OF THE UTILITY MODEL

An object of the utility model is to provide an elution device is used in heparin sodium preparation, aim at solving the problem that proposes in the background art.

In order to achieve the above purpose, the utility model adopts the following technical scheme: the utility model provides a heparin sodium preparation is with elution device, includes elution jar, water pump and rose box, elution jar's bottom fixedly connected with pumping pipe, the pumping end of water pump with pumping pipe is linked together, the drainage end of water pump is connected with row material pipe, arrange the other end of material pipe and install three shunt tubes, two baffles of rose box's inside fixedly connected with, two the baffle falls into three filter chamber with the inside of rose box, and is three the shunt tubes extends to threely respectively the inside of filter chamber, every all install the solenoid valve on the shunt tubes, every the inside of filter chamber all installs two and places the piece, every group place and all be equipped with the elution filter screen on the piece, the bottom fixedly connected with communicating pipe of rose box, install the solenoid valve on communicating pipe, the other end fixed connection of communicating pipe is in elution jar's top, elution jar's inside is equipped with rabbling mechanism.

In order to make the utility model discloses have the effect of stirring to the inside solution of elution jar, the utility model discloses a further technical scheme does, rabbling mechanism includes agitator motor, puddler and stirring leaf, agitator motor fixed connection is in on the elution jar, the puddler fixed connection be in agitator motor's output shaft end, stirring leaf fixed connection is in on the puddler, the inside of elution jar is equipped with heating mechanism.

In order to make the utility model discloses have the effect at specific temperature to the inside solution control of elution jar, the utility model discloses a further technical scheme does, heating mechanism includes the electrical heating stick, electrical heating stick fixed connection is in the inner wall of elution jar.

In order to ensure that the utility model discloses have and be convenient for add the resin to the inside effect of elution jar, the utility model discloses a further technical scheme does, elution jar's top fixedly connected with inlet pipe.

In order to make the utility model discloses have and be convenient for evenly add the effect to the elution jar inside with sodium chloride solution, the utility model discloses a further technical scheme does, the inside fixedly connected with shower of elution jar, the one end of shower extends to the outside of elution jar, a plurality of shower nozzles of fixedly connected with on the shower.

In order to make the utility model discloses have the effect between sealed elution filter screen and the rose box gap, the utility model discloses a further technical scheme does, is three the elution filter screen is all pegged graft the inside of rose box, the one end of elution filter screen is equipped with the sealing washer.

In order to make the utility model discloses have the effect of taking the elution filter screen out from the rose box is inside, the utility model discloses a further technical scheme does, every the handle is all installed to the one end of elution filter screen.

In order to make the utility model discloses have the effect of the solution discharge collection after will eluting, the utility model discloses a further technical scheme does, install the blowing pipe on the pumping pipe, install the solenoid valve on the blowing pipe.

The utility model has the advantages that:

1. vertical and sodium chloride solution that will treat the elution add to the inside of elution jar, stir its inside through rabbling mechanism, start the water pump and draw the solution that has heparin inside the elution jar through the pump tube after the stirring is accomplished, fill into the inside of rose box through row material pipe and shunt tubes, in the in-process of filling into rose box inside, open the solenoid valve on a shunt tube and close the solenoid valve on two other shunt tubes, resin in the solution filters through an elution filter screen, later through opening the solenoid valve on communicating pipe, arrange the solution after filtering again into elution jar inside and add the sodium chloride solution once more, repeat above-mentioned operation and elute once more, can fully elute the resin and draw the heparin composition that adsorbs wherein after the elution triple, the device has replaced the mode that uses three elution jar to elute in the past, thereby the area of using equipment has been reduced, and through taking out the elution filter screen from the inside of rose box, thereby make the device conveniently clear up the advantage of elution filter screen.

2. Drive the puddler through starting agitator motor and rotate, come to stir the inside solution of elution jar through the stirring leaf on the puddler, be convenient for heat the inside solution of elution jar through setting up the electrical heating stick, thereby make solution reach specific temperature value, be convenient for pour the resin into to the inside of elution jar through the inlet pipe, be convenient for spray sodium chloride solution to the inside of elution jar through the shower nozzle on the shower, make it and resin homogeneous mixing, through setting up the sealing washer, the leakproofness between elution filter screen one end and the rose box gap has been increased, be convenient for take the elution filter screen out from the inside of rose box through setting up the handle, through opening the solenoid valve on the blowing pipe after the cubic elution, be convenient for discharge the solution and collect.

Drawings

Fig. 1 is a schematic diagram of an elution tank according to an embodiment of the present invention.

Fig. 2 is a schematic structural diagram of a filter box in an embodiment of the present invention.

Fig. 3 is a rear view of a filter box according to an embodiment of the present invention.

In the figure: 1. an elution tank; 2. a material pumping pipe; 3. a water pump; 4. a discharge pipe; 5. a filter box; 6. a shunt tube; 7. a partition plate; 8. placing the blocks; 9. eluting the filter screen; 10. a communicating pipe; 11. a feeding pipe; 12. a spray pipe; 13. an electrical heating rod; 14. a stirring motor; 15. a stirring rod; 16. stirring blades; 17. a seal ring; 18. and discharging the pipe.

Detailed Description

The following description will further describe embodiments of the present invention with reference to the accompanying drawings.

As shown in fig. 1-3, an elution device for heparin sodium preparation, including elution jar 1, water pump 3 and rose box 5, elution jar 1's bottom fixedly connected with drawing pipe 2, the drawing end of water pump 3 is linked together with drawing pipe 2, the drainage end of water pump 3 is connected with row material pipe 4, three shunt tubes 6 are installed to row material pipe 4's the other end, two baffles 7 of rose box 5's inside fixedly connected with, two baffles 7 divide into three filter chamber with rose box 5's inside, three shunt tubes 6 extends to the inside of three filter chamber respectively, all install the solenoid valve on every shunt tubes 6, two inside of every filter chamber all install and place piece 8, every is placed and all is equipped with elution filter screen 9 on piece 8, rose box 5's bottom fixedly connected with communicating pipe 10, install the solenoid valve on communicating pipe 10, the other end fixed connection of communicating pipe 10 is at elution jar 1's top, elution jar 1's inside is equipped with rabbling mechanism.

In the embodiment, the vertical sodium chloride solution to be eluted and the sodium chloride solution are added into the elution tank 1, the inner part of the elution tank 1 is stirred by a stirring mechanism, after the stirring is finished, a water pump 3 is started to extract the solution with heparin in the elution tank 1 through a pumping pipe 2, the solution is filled into the filtering box 5 through a discharging pipe 4 and a shunt pipe 6, in the process of filling the filtering box 5, an electromagnetic valve on one shunt pipe 6 is opened to close electromagnetic valves on the other two shunt pipes 6, the resin in the solution is filtered through one elution filter screen 9, then the electromagnetic valve on a communicating pipe 10 is opened, the filtered solution is discharged into the elution tank 1 again to be added with the sodium chloride solution again, the operation is repeated for elution again, the resin can be fully eluted after elution is carried out for three times, the heparin components adsorbed in the resin can be extracted, the device replaces the traditional mode of using three elution tanks for elution, the occupied area of equipment is reduced, and the elution filter screen 9 is pumped out of the filtering box 5, so that the device can conveniently clean the filter screen of the elution 9.

In another embodiment of the present invention, the stirring rod 15 is driven to rotate by starting the stirring motor 14, and the solution inside the elution tank 1 is stirred by the stirring blade 16 on the stirring rod 15.

Specifically, the solution inside the elution tank 1 is conveniently heated by arranging the electric heating rod 13, so that the solution reaches a specific temperature value.

Furthermore, resin is poured into the interior of the elution tank 1 conveniently through the feeding pipe 11, and the sodium chloride solution is sprayed into the interior of the elution tank 1 conveniently through the spray head on the spray pipe 12, so that the sodium chloride solution and the resin are uniformly mixed.

Preferably, the sealing performance between one end of the elution filter screen 9 and the gap of the filter box 5 is increased by arranging the sealing ring 17, and the elution filter screen 9 is convenient to be drawn out from the inside of the filter box 5 by arranging the handle.

It should be noted that, after three times of elution, the solution is discharged and collected conveniently by opening the electromagnetic valve on the discharging pipe 18.

In the description of the present invention, unless otherwise expressly specified or limited, the terms "mounted," "connected," and "connected" are to be construed broadly, e.g., as meaning a fixed connection, a removable connection, or an integral connection; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meaning of the above terms in the present invention can be understood in specific cases to those skilled in the art.

It is obvious to a person skilled in the art that the invention is not restricted to details of the above-described exemplary embodiments, but that it can be implemented in other specific forms without departing from the spirit or essential characteristics of the invention. The present embodiments are therefore to be considered in all respects as illustrative and not restrictive, the scope of the invention being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein. Any reference sign in a claim should not be construed as limiting the claim concerned.

Furthermore, it should be understood that although the present specification describes embodiments, not every embodiment includes only a single embodiment, and such description is for clarity purposes only, and it is to be understood that all embodiments may be combined as appropriate by one of ordinary skill in the art to form other embodiments as will be apparent to those of skill in the art from the description herein.

Claims

1. The utility model provides a heparin sodium preparation is with elution device, characterized by, including elution jar (1), water pump (3) and rose box (5), the bottom fixedly connected with drawing pipe (2) of elution jar (1), the drawing end of water pump (3) with drawing pipe (2) are linked together, the drainage end of water pump (3) is connected with row material pipe (4), three shunt tubes (6) are installed to the other end of row material pipe (4), two baffle (7) of the inside fixedly connected with of rose box (5), two baffle (7) fall into three filter chamber with the inside of rose box (5), three shunt tubes (6) extend to three respectively the inside of filter chamber, every all install the solenoid valve on shunt tubes (6), every filter chamber's inside all installs two and places piece (8), every group place all be equipped with elution filter screen (9) on piece (8), the bottom fixedly connected with of rose box (5) is communicating pipe (10), install the solenoid valve on communicating pipe (10), the other end fixed connection of communicating pipe (10) is in elution jar (1) top, elution jar (1) is equipped with the stirring mechanism.

2. The elution device for preparing heparin sodium according to claim 1, wherein the stirring mechanism comprises a stirring motor (14), a stirring rod (15) and a stirring blade (16), the stirring motor (14) is fixedly connected to the elution tank (1), the stirring rod (15) is fixedly connected to an output rotating shaft end of the stirring motor (14), the stirring blade (16) is fixedly connected to the stirring rod (15), and a heating mechanism is arranged inside the elution tank (1).

3. The elution device for preparing heparin sodium according to the claim 2, wherein the heating mechanism comprises an electric heating rod (13), and the electric heating rod (13) is fixedly connected to the inner wall of the elution tank (1).

4. The elution device for preparing heparin sodium according to the claim 1, wherein the top of the elution tank (1) is fixedly connected with a feeding pipe (11).

5. The elution device for preparing heparin sodium according to claim 1, wherein a spray pipe (12) is fixedly connected to the inside of the elution tank (1), one end of the spray pipe (12) extends to the outside of the elution tank (1), and a plurality of nozzles are fixedly connected to the spray pipe (12).

6. The elution device for preparing heparin sodium according to claim 1, wherein three elution filter screens (9) are inserted into the filter box (5), and one end of each elution filter screen (9) is provided with a sealing ring (17).

7. The elution device for sodium heparin preparation according to claim 6, wherein a handle is installed at one end of each elution screen (9).

8. The elution device for preparing heparin sodium according to claim 1, wherein a discharging pipe (18) is installed on the pumping pipe (2), and an electromagnetic valve is installed on the discharging pipe (18).