CN217717433U - Liquid filling device with adjustable capacity - Google Patents

Liquid filling device with adjustable capacity Download PDF

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Publication number
CN217717433U
CN217717433U CN202221169821.4U CN202221169821U CN217717433U CN 217717433 U CN217717433 U CN 217717433U CN 202221169821 U CN202221169821 U CN 202221169821U CN 217717433 U CN217717433 U CN 217717433U
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China
Prior art keywords
piston
liquid
groove
liquid filling
filling device
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CN202221169821.4U
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Chinese (zh)
Inventor
邵萌
刘丽媛
张娟
程宇
梁超
陈忠
黄士昂
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Beijing Haisite Medical Examine Laboratory Co ltd
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Beijing Haisite Medical Examine Laboratory Co ltd
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Abstract

The utility model relates to a biological assay apparatus field especially relates to a capacity adjustable liquid filling device, including shell, liquid feeding portion, capacity adjustment portion, be equipped with first spacing draw-in groove, the spacing draw-in groove of second, liquid outlet, inlet on the shell, liquid feeding portion includes piston core bar and establishes ties main piston, first sealing piston, the sealed piston of second on the piston core bar, first spacing draw-in groove is used for spacing first sealing piston, the spacing draw-in groove of second is used for spacing second sealing piston, part shell and first sealing piston, the sealed piston of second between first spacing draw-in groove and the spacing draw-in groove of second form the liquid reserve tank jointly, liquid feeding portion still is equipped with the honeycomb duct, honeycomb duct one end is used for being connected with the inlet, and the other end communicates with the liquid reserve tank through piston core bar is inside. The liquid filling device can quantitatively and continuously add samples and improve the sample adding speed.

Description

Liquid filling device with adjustable capacity
Technical Field
The utility model relates to a biological assay apparatus field especially relates to a capacity adjustable liquid filling device.
Background
Flow Cytometry (FCM) is a detection means for quantitatively analyzing and sorting single cells or other biological particles on a functional level, and has the characteristics of high speed, high precision, good accuracy and the like. At present, flow cytometry is widely applied to the fields of clinical medicine and basic medicine research such as immunology, hematology, oncology, cell biology, cytogenetics, biochemistry and the like. The flow cytometry detection technology mainly comprises three major parts, namely sample processing, sample loading and data analysis, and at present, the sample processing part mainly depends on manual operation, wherein the sample loading is particularly important work throughout the experiment; the more common sample-adding devices are: pipettors, droppers, tip sampling bottles, and the like; in these sample-feeding devices, each advantage also has its own disadvantages, such as: pipettes and droppers can be used for quantification, but liquid needs to be repeatedly sucked; the sharp-mouth sample adding bottle can continuously add samples, but cannot quantitatively add the samples; then, can last the speed of application of sample in order to promote the application of sample under the prerequisite of guaranteeing can be quantitative, it is very helpful to improve experimental efficiency.
SUMMERY OF THE UTILITY MODEL
In view of the above-mentioned shortcomings of the prior art, the present invention provides a liquid filling device with adjustable volume, which is used to solve the problems in the prior art.
For realizing above-mentioned purpose and other relevant purpose, the utility model provides a capacity adjustable liquid filling device, liquid filling device includes shell, liquid feeding portion, capacity adjustment portion, be equipped with first spacing draw-in groove, the spacing draw-in groove of second, liquid outlet, inlet on the shell, liquid feeding portion includes the piston core bar and establishes ties main piston, first sealing piston, the second sealing piston on the piston core bar in proper order, piston core bar cavity, first spacing draw-in groove is used for spacing first sealing piston, the spacing draw-in groove of second is used for spacing second sealing piston, part shell and first sealing piston, the common liquid reserve tank that forms of second sealing piston between first spacing draw-in groove and the spacing draw-in groove of second, liquid feeding portion still is equipped with the honeycomb duct, honeycomb duct one end is used for being connected with the inlet, and the other end communicates with the liquid reserve tank through the piston core bar is inside, capacity adjustment portion communicates with each other with the liquid reserve tank.
As above, the utility model discloses a capacity adjustable liquid filling device has following beneficial effect: guarantee can quantitatively last the application of sample, promote the speed of application of sample, improve experimental efficiency.
Drawings
Fig. 1 is a perspective view of the volume-adjustable liquid filling apparatus according to the present invention.
Fig. 2 is a partial sectional view of the capacity adjusting portion of the capacity-adjustable liquid filling apparatus according to the present invention.
Fig. 3 is a state diagram of the liquid filling apparatus with adjustable volume according to the present invention.
Fig. 4 is a state diagram showing the liquid storage of the liquid filling apparatus with adjustable capacity according to the present invention.
Description of the element reference
1. Outer casing
11. First limiting clamping groove
12. Second limit clamping groove
13. Liquid outlet
14. Liquid inlet
15. Liquid storage tank
2. Liquid adding part
21. Piston core rod
211. Pressing handle
22. Main piston
23. First sealing piston
24. Second sealing piston
25. Flow guide pipe
251. Long pipe part
252. Short pipe part
253. Air vent
26. Spring
3. Capacity adjustment unit
31. Adjusting tank
32. Adjusting rod
33. Adjusting piston
Detailed Description
The following description is provided for illustrative purposes, and other advantages and features of the present invention will become apparent to those skilled in the art from the following detailed description.
Please refer to the attached drawings. It should be understood that the structure, ratio, size and the like shown in the drawings attached to the present specification are only used for matching with the content disclosed in the specification, so as to be known and read by those skilled in the art, and are not used for limiting the limit conditions that the present invention can be implemented, so that the present invention has no technical essential meaning, and any structure modification, ratio relationship change or size adjustment should still fall within the scope that the technical content disclosed in the present invention can cover without affecting the function that the present invention can produce and the purpose that the present invention can achieve. Meanwhile, the terms such as "upper", "lower", "left", "right", "middle" and "one" used in the present specification are for convenience of description, and are not intended to limit the scope of the present invention, and changes or adjustments of the relative relationship thereof may be made without substantial technical changes, and the present invention is also regarded as the scope of the present invention.
As shown in fig. 1, the utility model provides a capacity adjustable liquid filling device, liquid filling device includes shell 1, liquid portion 2, capacity adjustment portion 3 of adding, be equipped with first spacing draw-in groove 11, the spacing draw-in groove 12 of second, liquid outlet 13, inlet 14 on the shell 1, liquid portion 2 of adding includes piston core bar 21 and establishes ties master piston 22, first sealed piston 23, the sealed piston 24 of second on piston core bar 21 in proper order, piston core bar 21 cavity, first spacing draw-in groove 11 is used for spacing first sealed piston 23, the spacing draw-in groove 12 of second is used for spacing second sealed piston 24, part shell between first spacing draw-in groove 11 and the spacing draw-in groove 12 of second forms liquid storage tank 15 with first sealed piston 23, the sealed piston 24 of second jointly, capacity adjustment portion 3 communicates with each other with liquid storage tank 15, liquid portion 2 of adding still is equipped with honeycomb duct 25, honeycomb duct 25 one end is used for being connected with inlet 14, and the other end communicates with liquid storage tank 15 through piston core bar 21 is inside.
The inner diameter of the shell 1 is 30-50 mm; the length is 70-150 mm. In one embodiment, the inner diameter of the housing 1 is 40mm; the length is 90mm.
In the embodiment shown in fig. 1, the first limit card slot 11 and the second limit card slot 12 are V-shaped grooves on the housing 1.
The top end of the piston core rod 21 is provided with a pressing handle 211.
In one embodiment, the plunger rod 21 is provided with an air hole at the pressing end (i.e., the upper end in fig. 1).
Preferably, the part of the piston core rod 21 between the first sealing piston 23 and the second sealing piston 24 is two hard connecting rods. The distance between the two hard connecting rods is larger than the width of the corresponding position of the capacity adjusting part 3. Thus, the space for the movement of the volume adjusting section 3 is reserved, so that the liquid in the flow guide pipe 25 can be made to flow to the liquid reservoir 15 to the maximum extent without interfering with the progress of the volume adjusting section 3.
The outer diameter of the piston core rod 21 is 15-30 mm; the total length is 90-130 mm. In one embodiment, the
The outer diameter of the piston core rod 21 is 18mm, and the total length is 110mm. All dimensions of the invention are defined only as ratios between the parts, and smaller or larger sized liquid filling devices can also be made according to the ratios.
The primary piston 22 is cylindrical.
The diameter of the main piston 22 is the same as the inner diameter of the housing 1. The height of the main piston 22 is 20-30 mm. In one embodiment, the height of the primary piston is 25mm.
A spring 26 is sleeved on the piston core rod 21 between the main piston 22 and the first sealing piston 23. The first limit slot 11 is used for limiting the spring 26 and the first sealing piston 23. The spring 26 can rebound the piston core bar 21, the main piston 22, the first sealing piston 23 and the second sealing piston 24 to the original position after the pressing handle 211 is released, so that liquid can be stored in the liquid storage tank 15, and the next liquid adding is facilitated.
The shape of first sealing piston 23 and the shape of first spacing draw-in groove 11 are matched in order to reach first sealing piston 23 stroke during the top with first spacing draw-in groove 11 sealing connection, down, break away from sealedly with first spacing draw-in groove 11, make liquid storage tank 15 and the communicating purpose of liquid feeding portion 2 inner chamber.
The shape of the second sealing piston 24 is matched with that of the second limiting clamping groove 12 so as to achieve the purpose that the second sealing piston 24 is in sealing connection with the second limiting clamping groove 12 at the uppermost end of the stroke and is separated from the sealing with the second limiting clamping groove 12 during descending, so that the liquid storage tank 15 is communicated with the liquid outlet 13.
In the embodiment shown in fig. 1, the first sealing piston 23 and the second sealing piston 24 are in the form of circular truncated cones.
The distance between the first limiting clamping groove 11 and the second limiting clamping groove 12 is 13-19 mm, for example, 16mm.
The inner diameter of the part of the shell between the first limit clamping groove 11 and the second limit clamping groove 12 can be larger than that of the other part of the shell. For example, the inner diameter of the part of the housing between the first limit slot 11 and the second limit slot 12 may be 50-55 mm, for example, 52mm.
In one embodiment, the reservoir 15 has a volume of 5 to 15ml.
When the piston core rod 21 is pressed, the piston core rod 21 drives the second sealing piston 24 to move, so that a flow channel is formed between the second sealing piston 24 and the second limiting clamping groove 12, and the liquid in the liquid storage tank 15 flows out to the liquid outlet 13.
In the embodiment shown in fig. 1, the fluid guiding tube 25 comprises a long tube portion 251 and a short tube portion 252 connected with each other, the long tube portion 251 is disposed inside the piston core rod 21 and is parallel to the axial direction of the piston core rod 21, and the short tube portion 252 is used for connecting with the fluid inlet 14 and further connecting with an external fluid reservoir.
One end of the long pipe part 251 is provided with an air vent 253, and the other end is a flow guide pipe outlet. The air hole 253 is higher than the liquid inlet end of the short pipe part 252. This prevents liquid from escaping through the vent during the accumulation of liquid.
As shown in fig. 1, the angle α between the long pipe portion 251 and the short pipe portion 252 is a right angle or an obtuse angle. Preferably, the angle α is an obtuse angle. The obtuse angle α enables the liquid to flow rapidly to the long tubular portion 251.
The short pipe portion 252 passes through the piston core rod 21 and is flush with the side wall of the main piston 22 through the interior of the main piston 22 to its end. The port of the short tube portion 252 communicates with an external reservoir during the process of storing liquid in the reservoir 15. In the process of discharging the liquid from the liquid storage tank 15, the short tube part 252 moves along with the piston core rod 21, so that the port of the short tube part is disconnected from the external liquid storage bottle, at this time, the main piston can be used for plugging the external liquid storage bottle to stop storing the liquid, and the switch of the external liquid storage bottle can be also closed to stop storing the liquid.
In one embodiment, the material of the flow guide tube 25 is glass. The inner diameter of the flow guide pipe 25 is 1 to 3mm, for example, 2mm.
The capacity adjusting part 3 comprises an adjusting tank 31, an adjusting rod 32 and an adjusting piston 33, the adjusting tank is arranged on the outer wall of the liquid storage tank 15, the adjusting rod 32 is connected with the adjusting piston 33, the adjusting piston 33 is arranged in the adjusting tank 31, and scales are arranged on the outer wall of the adjusting tank 31.
The inner diameter of the regulating reservoir 31 is smaller than the inner diameter of the piston core rod 21, so that the piston core rod 21 is ensured not to influence the movement of the regulating piston 33. In one embodiment, the inner diameter of the conditioning tank 31 is 10 to 15mm, for example 12mm.
In one embodiment, the volume range adjusted by the volume adjusting part 3 is 0 to 5ml. Correspondingly, the scale is 0-5 ml.
The volume adjusting part 3 controls the adjusting piston 33 to push the liquid storage tank 15 by pushing the adjusting rod 32, namely, the liquid storage tank 15 is squeezed to occupy the volume, so as to control the volume of the reagent in the liquid storage tank 15.
The liquid filling device with adjustable capacity of the invention is used as follows:
as shown in fig. 3, when the pressing handle 211 is pressed, the spring 26 is compressed, the piston core rod 21 drives the flow guide tube 25, the main piston 22, the first sealing piston 23, and the second sealing piston 24 to move, so that the port of the short tube portion 252 is disconnected from the external reagent bottle, the main piston 22 blocks the outlet of the external reagent bottle, and a flow channel is formed between the second sealing piston 24 and the second limiting clamping groove 12, so that the liquid in the liquid storage tank 15 flows out to the liquid outlet 13, and then flows out through the liquid outlet 13 to complete the liquid filling process.
After the liquid is filled, the pressing handle 211 is released, as shown in fig. 4, the spring 26 automatically rebounds to drive the main piston 22, the piston core rod 21, the flow guide pipe 25, the first sealing piston 23 and the second sealing piston 24 to return to the original positions, the flow guide pipe 25 is communicated with an external reagent bottle again, the first sealing piston 23 is sealed with the first limiting clamping groove 11 again, the second sealing piston is sealed with the second limiting clamping groove 12 again to form a sealed liquid storage tank 15, the liquid storage tank 15 can be stored with liquid again, the adjusting rod 32 can be pushed to control the volume of the liquid storage tank 15 at the moment, and the next filling can be performed after the liquid storage is completed. If the liquid is not needed to be used after the filling is finished, the switch of the external reagent bottle can be closed, and the liquid is not stored in the liquid filling device. The air pressure inside the device is maintained to be balanced through the air holes 253 in the whole process of liquid storage and filling.
To sum up, the utility model discloses effectively overcome all kinds of shortcomings among the prior art and had high industrial utilization value.
The above embodiments are merely illustrative of the principles and effects of the present invention, and are not intended to limit the present invention. Modifications and variations can be made to the above-described embodiments by those skilled in the art without departing from the spirit and scope of the present invention. Accordingly, it is intended that all equivalent modifications or changes which may be made by those skilled in the art without departing from the spirit and technical spirit of the present invention be covered by the claims of the present invention.

Claims (13)

1. The utility model provides a capacity adjustable liquid filling device, its characterized in that, liquid filling device includes shell (1), liquid feeding portion (2), capacity regulation portion (3), be equipped with first spacing draw-in groove (11), second spacing draw-in groove (12), liquid outlet (13), inlet (14) on shell (1), liquid feeding portion (2) include piston core bar (21) and establish ties master piston (22), first sealed piston (23), second sealed piston (24) on piston core bar (21) in proper order, piston core bar (21) cavity, first spacing draw-in groove (11) are used for spacing first sealed piston (23), second spacing draw-in groove (12) are used for spacing second sealed piston (24), part shell between first spacing draw-in groove (11) and the spacing draw-in groove of second (12) and first sealed piston (23), second sealed piston (24) form liquid storage tank (15) jointly, liquid feeding portion (2) still are equipped with liquid storage tank (25), honeycomb duct (25) one end is used for being connected with first sealed piston (23), the other end is connected with liquid storage tank (15) through liquid storage tank (15), liquid storage tank (15) and liquid guide pipe (3), volume regulation portion (15).
2. Liquid filling device according to claim 1, characterized in that the first and second limiting notches (11, 12) are V-shaped grooves on the housing (1).
3. The liquid filling device according to claim 1, wherein a pressing handle (211) is provided at the top end of the plunger rod (21).
4. Liquid filling device according to claim 1, wherein the part of the piston core rod (21) between the first sealing piston (23) and the second sealing piston (24) is two rigid connecting rods.
5. Liquid filling device according to claim 1, characterized in that a spring (26) is sleeved on the piston core rod (21) between the main piston (22) and the first sealing piston (23), and the first limiting clamping groove (11) is used for limiting the spring (26) and the first sealing piston (23).
6. Liquid filling device according to claim 1, wherein the shape of the first sealing piston (23) matches the shape of the first limit catch (11); and/or the shape of the second sealing piston (24) is matched with that of the second limiting clamping groove (12).
7. Liquid filling device according to claim 1, wherein the first sealing piston (23) and/or the second sealing piston (24) is frustoconical.
8. The liquid filling apparatus as claimed in claim 1, wherein the flow guide tube (25) comprises a long tube portion (251) and a short tube portion (252) connected to each other, the long tube portion (251) being provided in the piston core rod (21) in parallel with an axial direction of the piston core rod (21), the short tube portion (252) being adapted to be connected to the liquid inlet (14).
9. Liquid filling device according to claim 8, characterized in that the angle a between the long pipe section (251) and the short pipe section (252) is a right or obtuse angle.
10. Liquid filling device according to claim 8, characterized in that the short tube section (252) extends out of the plunger core rod (21) through the interior of the main plunger (22) to its end flush with the side wall of the main plunger (22).
11. The liquid filling apparatus as claimed in claim 8, wherein the long tube portion (251) is provided with an air hole (253) at one end and a draft tube outlet at the other end.
12. The liquid filling apparatus according to claim 11, wherein the air vent (253) is located higher than an inlet end of the short pipe portion (252).
13. The liquid filling apparatus according to claim 1, wherein the volume adjusting portion (3) comprises an adjusting tank (31), an adjusting rod (32) and an adjusting piston (33), the adjusting tank is disposed on an outer wall of the liquid storage tank (15), the adjusting rod (32) is connected with the adjusting piston (33), the adjusting piston (33) is disposed in the adjusting tank (31), and scales are disposed on an outer wall of the adjusting tank (31).
CN202221169821.4U 2022-05-16 2022-05-16 Liquid filling device with adjustable capacity Active CN217717433U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202221169821.4U CN217717433U (en) 2022-05-16 2022-05-16 Liquid filling device with adjustable capacity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202221169821.4U CN217717433U (en) 2022-05-16 2022-05-16 Liquid filling device with adjustable capacity

Publications (1)

Publication Number Publication Date
CN217717433U true CN217717433U (en) 2022-11-01

Family

ID=83792377

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202221169821.4U Active CN217717433U (en) 2022-05-16 2022-05-16 Liquid filling device with adjustable capacity

Country Status (1)

Country Link
CN (1) CN217717433U (en)

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