CN217638891U

CN217638891U - Sample introduction device and liquid chromatograph

Info

Publication number: CN217638891U
Application number: CN202222294519.8U
Authority: CN
Inventors: 张红伟; 李晓建; 邓世义; 刘巧; 王忍; 李娜娜
Original assignee: Beijing Novogene Technology Co ltd
Current assignee: Beijing Novogene Technology Co ltd
Priority date: 2022-08-30
Filing date: 2022-08-30
Publication date: 2022-10-21
Anticipated expiration: 2032-08-30

Abstract

The utility model provides a sampling device and liquid chromatograph, sampling device includes: a mounting plate having a sample inlet; a lifting part, at least a part of which is arranged on the mounting plate in a lifting way; the sampling part comprises a pushing part and a driving mechanism, the pushing part is used for bearing a sample, the driving mechanism is connected with a lifting part, the lifting part drives the driving mechanism to lift, and the driving mechanism is in driving connection with the pushing part to drive the pushing part to enter and exit the sampling port. By adopting the scheme, the lifting part is matched with the driving mechanism, so that the driving mechanism can drive the pushing piece to enter and exit the sample inlet while the lifting part drives the driving mechanism to lift, and sample introduction operation and plate taking operation on a sample are realized; the sampling device of this scheme of utilization has abandoned the mode through manual operation among the prior art, but sets up lift portion and actuating mechanism to through the cooperation between lift portion and the actuating mechanism, effectively solved the low problem of the liquid chromatograph degree of automation among the prior art.

Description

Sample introduction device and liquid chromatograph

Technical Field

The utility model relates to a liquid chromatograph technical field particularly, relates to a sampling device and liquid chromatograph.

Background

The liquid chromatograph is an instrument which firstly separates a mixture and then analyzes and identifies the mixture by utilizing the difference of the distribution ratio of the mixture between two liquids which are liquid-solid or immiscible. The liquid chromatograph in and out of the prior art is mainly operated manually, and the detection cavity of the liquid chromatograph has narrow in and out space, so that automatic integration cannot be realized.

SUMMERY OF THE UTILITY MODEL

The utility model provides a sampling device and liquid chromatograph to the liquid chromatograph who solves among the prior art needs manual sample, the problem of inconvenient operation.

In order to solve the above problem, according to the utility model discloses an aspect, the utility model provides a sampling device, include: a mounting plate having a sample inlet; a lifting part, at least a part of which is arranged on the mounting plate in a lifting way; the sampling part comprises a pushing part and a driving mechanism, the pushing part is used for bearing a sample, the driving mechanism is connected with a lifting part, the lifting part drives the driving mechanism to lift, and the driving mechanism is in driving connection with the pushing part to drive the pushing part to enter and exit the sampling port.

Furthermore, the driving mechanism comprises a connecting piece, a connecting rod mechanism and a first driving part, the connecting piece and the first driving part are both installed on the lifting part, one end of the connecting rod mechanism is in driving connection with the pushing piece, the other end of the connecting rod mechanism is movably connected with the connecting piece, the first driving part is in driving connection with the connecting rod mechanism, and the connecting rod mechanism drives the pushing piece to move horizontally.

Further, link mechanism includes first transfer line, second transfer line and parallel arrangement's first axis of rotation, the second axis of rotation, third axis of rotation and fourth axis of rotation, the one end and the first axis of rotation fixed connection of first transfer line, first axis of rotation and connecting piece are articulated, the other end of first transfer line passes through the second axis of rotation and the propelling movement piece is articulated, the one end of second transfer line passes through the third axis of rotation and the connecting piece is articulated, the other end of second transfer line passes through the fourth axis of rotation and the propelling movement piece is articulated, first drive division and first axis of rotation drive are connected.

Further, the pushing part comprises a first block body, a second block body, a third block body and a pushing plate, wherein two sides of the second block body are respectively connected with the first block body and the third block body, the pushing plate is connected with the second block body and used for bearing a sample, a second rotating shaft sequentially penetrates through the first block body, the second block body and the third block body, the two first transmission rods are respectively positioned on the outer side wall of the first block body and the outer side wall of the second block body and hinged to the second rotating shaft, the fourth rotating shaft penetrates through the first block body and the third block body, and the second transmission rod is positioned between the first block body and the third block body and hinged to the fourth rotating shaft.

Further, first drive division includes first driving motor and first conveyer belt, and first driving motor installs in lift portion, and first driving motor's output shaft passes through first conveyer belt and first rotating shaft to be connected, and first driving motor's output shaft drives first conveyer belt and rotates.

Further, the lift portion includes slider, second drive division and two guide rails of vertical setting in the introduction port both sides, and two guide rails all are connected with the mounting panel, and slider and two equal sliding fit of guide rail, second drive division and slider connection, second drive division drive slider go up and down, and connecting piece and first drive division are all installed on the slider, and wherein, the introduction port can be blocked or dodged to the slider.

Furthermore, the sliding part comprises a supporting plate and two sliding blocks, two ends of the supporting plate are respectively connected with the two sliding blocks, the two sliding blocks are respectively in sliding fit with the two guide rails, the second driving part is in driving connection with the at least one sliding block, and the connecting part is connected with the supporting plate.

Further, the second driving portion comprises a second driving motor, a second conveying belt and a fixing piece, the second driving motor is installed on the installation plate, the second conveying belt is connected with the sliding block through the fixing piece, and an output shaft of the second driving motor drives the second conveying belt to rotate.

Further, the backup pad includes interconnect's plate body and rack, and the both ends of plate body are connected with two sliders respectively, and the rack is located the top of connecting piece, and the rack is used for supporting propelling movement spare, and the rack has the mouth of dodging, and link mechanism passes the mouth of dodging.

According to the utility model discloses an on the other hand provides a liquid chromatograph, and liquid chromatograph includes major structure and foretell sampling device, and sampling device detachably installs on major structure's lateral wall, and the major structure has the detection chamber, detects chamber and sampling device's introduction port intercommunication, and sampling device's propelling movement spare is used for transporting the sample to the detection chamber.

Use the technical scheme of the utility model, a sampling device is provided, include: a mounting plate having a sample inlet; a lifting part, at least a part of which is arranged on the mounting plate in a lifting way; the sample injection part comprises a pushing part and a driving mechanism, the pushing part is used for bearing samples, the driving mechanism is connected with the lifting part, the lifting part drives the driving mechanism to lift, and the driving mechanism is in driving connection with the pushing part so as to drive the pushing part to enter and exit the sample injection port. By adopting the scheme, the driving mechanism is connected with the lifting part and is in driving connection with the pushing part, and the lifting part drives the driving mechanism to lift and the driving mechanism can drive the pushing part to enter and exit the sample inlet at the same time through the matching between the lifting part and the driving mechanism, so that the sample feeding operation and the plate taking operation on the sample are realized; the sampling device of this scheme of utilization has abandoned the mode through manual operation among the prior art, but sets up lift portion and actuating mechanism to through the cooperation between lift portion and the actuating mechanism, effectively solved the low problem of the liquid chromatograph degree of automation among the prior art. The sample feeding operation of the sample refers to that the sample on the pushing piece is fed into the sample inlet from an initial position through the matching between the lifting part and the driving mechanism; the sample taking operation refers to that after the sample is sent into the sample inlet, the pushing member is restored to the initial position through the matching between the lifting part and the driving mechanism.

Drawings

The accompanying drawings, which form a part of the present application, are included to provide a further understanding of the invention, and are incorporated in and constitute a part of this specification, illustrate embodiments of the invention and together with the description serve to explain the invention and not to limit the invention. In the drawings:

fig. 1 shows a schematic structural diagram of a sample introduction device provided by an embodiment of the present invention in a first state;

FIG. 2 is a schematic view of the sample injection device in FIG. 1 in a second state;

FIG. 3 is a schematic structural diagram of the sample injection device in FIG. 1 in a third state;

FIG. 4 shows a partial enlarged view of FIG. 3;

fig. 5 shows a schematic structural diagram of a liquid chromatograph according to a second embodiment of the present invention.

Wherein the figures include the following reference numerals:

10. mounting a plate; 11. a sample inlet;

20. a lifting part; 21. a slider; 211. a support plate; 2111. a plate body; 2112. placing a rack; 212. a slider; 22. a second driving section; 221. a second drive motor; 222. a second conveyor belt; 23. a guide rail;

30. a sample introduction part; 31. a pusher member; 311. a first block; 312. a second block; 313. a third block body; 314. a push plate; 32. a drive mechanism; 321. a connecting member; 322. a link mechanism; 3221. a first drive lever; 3222. a second transmission rod; 3223. a first rotating shaft; 3224. a second rotating shaft; 3225. a third rotating shaft; 3226. a fourth rotating shaft; 323. a first driving section; 3231. a first drive motor;

40. a main body structure.

Detailed Description

The technical solution in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention. It is to be understood that the embodiments described are only some embodiments of the invention, and not all embodiments. The following description of at least one exemplary embodiment is merely illustrative in nature and is in no way intended to limit the invention, its application, or uses. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative efforts belong to the protection scope of the present invention.

As shown in fig. 1 to 4, an embodiment of the present invention provides a sample injection device, including: a mounting plate 10 having a sample inlet 11; an elevating unit 20, at least a part of the elevating unit 20 being provided to be elevated on the mounting plate 10; sample portion 30, sample portion 30 includes propelling movement piece 31 and actuating mechanism 32, and propelling movement piece 31 is used for bearing the weight of the sample, and actuating mechanism 32 and lift portion 20 are connected, and lift portion 20 drives actuating mechanism 32 and goes up and down, and actuating mechanism 32 and propelling movement piece 31 drive are connected to drive propelling movement piece 31 business turn over introduction port 11.

By adopting the scheme, the driving mechanism 32 is connected with the lifting part 20, the driving mechanism 32 is in driving connection with the pushing piece 31, and the lifting part 20 is matched with the driving mechanism 32, so that the lifting part 20 drives the driving mechanism 32 to lift, and meanwhile, the driving mechanism 32 can drive the pushing piece 31 to enter and exit the sample inlet, namely, the sample feeding operation and the plate taking operation of the sample are realized; by means of the sample introduction device, a manual operation mode in the prior art is abandoned, the lifting portion 20 and the driving mechanism 32 are arranged, the sample introduction operation and the plate taking operation of samples are achieved through cooperation between the lifting portion 20 and the driving mechanism 32, and the problem that the automation degree of a liquid chromatograph in the prior art is low is effectively solved. The sample feeding operation of the sample refers to feeding the sample on the pushing member 31 into the sample inlet 11 from an initial position through the cooperation between the lifting part 20 and the driving mechanism 32; the sample taking operation means that the pusher 31 is returned to the initial position by the cooperation between the elevating portion 20 and the driving mechanism 32 after the sample is fed into the sample inlet 11.

The driving mechanism 32 includes a connecting member 321, a link mechanism 322 and a first driving portion 323, the connecting member 321 and the first driving portion 323 are both installed on the lifting portion 20, one end of the link mechanism 322 is in driving connection with the pushing member 31, the other end of the link mechanism 322 is movably connected with the connecting member 321, the first driving portion 323 is in driving connection with the link mechanism 322, and the link mechanism 322 drives the pushing member 31 to move horizontally. By adopting the connection mode, the link mechanism 322 is driven to rotate by the first driving part 323, one end of the link mechanism 322 is in driving connection with the pushing element 31, the other end of the link mechanism 322 is movably connected with the connecting element 321, and then the link mechanism 322 drives the pushing element 31 to rotate, so that the pushing element 31 can enter and exit the sample inlet. The link mechanism 322 drives the pushing member 31 to move horizontally, so that the pushing member 31 is prevented from rotating, and stability in the movement process is ensured.

Further, the link mechanism 322 includes a first transmission rod 3221, a second transmission rod 3222, and a first rotation shaft 3223, a second rotation shaft 3224, a third rotation shaft 3225, and a fourth rotation shaft 3226 arranged in parallel, wherein one end of the first transmission rod 3221 is fixedly connected to the first rotation shaft 3223, the first rotation shaft 3223 is hinged to the connecting member 321, the other end of the first transmission rod 3221 is hinged to the pushing member 31 through the second rotation shaft 3224, one end of the second transmission rod 3222 is hinged to the connecting member 321 through the third rotation shaft 3225, the other end of the second transmission rod 3222 is hinged to the pushing member 31 through the fourth rotation shaft 3226, and the first driving portion 323 is drivingly connected to the first rotation shaft 3223. Through the above arrangement, the first driving portion 323 drives the first rotating shaft 3223 to rotate, and the first rotating shaft 3223 drives the first driving rod 3221 to rotate, so as to drive the second driving rod 3222 to rotate, that is, the pushing member 31 is moved. First rotating shaft 3223, second rotating shaft 3224, third rotating shaft 3225, and fourth rotating shaft 3226 are arranged in parallel, so that first driving rod 3221 and second driving rod 3222 can drive pushing element 31 to translate when rotating. The first driving rod 3221 and the second driving rod 3222 are arc-shaped, so that the injection port 11 can be avoided in the rotating process.

The pushing member 31 includes a first block 311, a second block 312, a third block 313 and a pushing plate 314, two sides of the second block 312 are respectively connected to the first block 311 and the third block 313, the pushing plate 314 is connected to the second block 312, the pushing plate 314 is used for carrying a sample, a second rotating shaft 3224 sequentially passes through the first block 311, the second block 312 and the third block 313, two first driving rods 3221 are respectively located on outer sidewalls of the first block 311 and the second block 312 and hinged to the second rotating shaft 3224, a fourth rotating shaft 3226 passes through the first block 311 and the third block 313, and a second driving rod 3222 is located between the first block 311 and the third block 313 and hinged to the fourth rotating shaft 3226. By adopting the above connection manner, the second transmission rod 3222 and the two first transmission rods 3221 can drive the push plate 314 to translate, so that sample feeding operation and plate taking operation are realized. Wherein, two first transmission rods 3221 are respectively disposed on the outer sidewalls of the first block 311 and the second block 312 and hinged to the second rotation shaft 3224, so that stability and reliability during operation can be ensured.

In this embodiment, the first driving part 323 includes a first driving motor 3231 and a first belt conveyor, the first driving motor 3231 is installed on the lifting part 20, an output shaft of the first driving motor 3231 is connected to the first rotating shaft 3223 through the first belt conveyor, and an output shaft of the first driving motor 3231 drives the first belt conveyor to rotate. The first conveyor belt is driven to rotate by an output shaft of the first driving motor 3231, and the first conveyor belt is connected with the first rotating shaft 3223, so that the first conveyor belt can drive the first rotating shaft 3223 to rotate; the first driving motor 3231 is installed on the elevating part 20 so that the structure is more compact.

Specifically, the lifting portion 20 includes a sliding member 21, a second driving portion 22 and two guide rails 23 vertically disposed on two sides of the sample inlet 11, the two guide rails 23 are connected to the mounting plate 10, the sliding member 21 and the two guide rails 23 are in sliding fit, the second driving portion 22 is connected to the sliding member 21, the second driving portion 22 drives the sliding member 21 to lift, the connecting member 321 and the first driving portion 323 are both mounted on the sliding member 21, and the sliding member 21 can block or avoid the sample inlet 11. By adopting the above connection manner, the second driving portion 22 drives the sliding member 21 to move up and down, so that the sliding member 21 can slide up and down along the two guide rails 23, and the sliding member 21 drives the connecting member 321 and the first driving portion 323 to slide up and down. As shown in fig. 1, when the sample injection device is at an initial position, the sliding member 21 can block the sample injection port 11, so that the sealing effect of the sample injection device is ensured; FIG. 1 is a diagram showing a state where a sample injection device is in an initial position (i.e., a first state); FIG. 2 is a diagram showing a sample injection device in a process of sample injection operation (i.e., a second state); fig. 3 is a diagram showing a state where the sample introduction device sends the sample to a predetermined position (i.e., a third state).

The sliding member 21 includes a supporting plate 211 and two sliding blocks 212, two ends of the supporting plate 211 are respectively connected with the two sliding blocks 212, the two sliding blocks 212 are respectively in sliding fit with the two guide rails 23, the second driving portion 22 is in driving connection with at least one sliding block 212, and the connecting member 321 is connected with the supporting plate 211. Two sliding blocks 212 are arranged and can be in sliding fit with the two guide rails 23; the second driving part 22 can drive at least one slider 212 to move. Wherein, the supporting plate 211 can block or avoid the sample inlet 11.

Further, the second driving part 22 includes a second driving motor 221, a second belt 222 and a fixing member, the second driving motor 221 is mounted on the mounting plate 10, the second belt 222 is connected with the slider 212 through the fixing member, and an output shaft of the second driving motor 221 drives the second belt 222 to rotate. The second belt 222 is driven to rotate by the output shaft of the second driving motor 221, and the second belt 222 can drive the sliding block 212 to lift because the second belt 222 is connected with the sliding block 212 through the fixing piece.

Specifically, the supporting plate 211 includes a plate body 2111 and a placing frame 2112 that are connected to each other, two ends of the plate body 2111 are respectively connected to the two sliders 212, the placing frame 2112 is located above the connecting member 321, the placing frame 2112 is used for supporting the pushing member 31, the placing frame 2112 has an avoidance opening, and the link mechanism 322 passes through the avoidance opening. By arranging the placing frame 2112, and the placing frame 2112 is positioned above the connecting piece 321, the pushing piece 31 can be supported; the avoidance opening is arranged, and when the connecting rod mechanism 322 rotates, the avoidance function can be achieved. Wherein, rack 2112 has the stopper that a plurality of intervals set up all around, and the stopper can play limiting displacement to pushing member 31 to the inside wall of stopper has the direction inclined plane, when pushing member 31 puts into on rack 2112, can play the guide effect.

As shown in fig. 5, the second embodiment of the utility model provides a liquid chromatograph, liquid chromatograph includes major structure 40 and foretell sampling device, and sampling device detachably installs on major structure 40's lateral wall, and major structure 40 has the detection chamber, detects chamber and sampling device's introduction port 11 intercommunication, and sampling device's propelling movement piece 31 is used for transporting the sample to the detection chamber. By adopting the scheme, the sample can be conveyed to the detection cavity through the pushing component 31 of the sample injection device without the manual operation mode, and the working efficiency and the automation degree of the liquid chromatograph are effectively improved. Wherein, liquid chromatograph still includes sealed the pad, sets up sealed the pad at the introduction port, installs mounting panel 10 in the sampling device on the lateral wall of major structure 40 through the fastener afterwards, has further guaranteed the inside sealed effect of liquid chromatograph like this.

Optionally, the mounting plate 10 also has an access port disposed below the sample inlet 11. The sample feeding device can be overhauled and maintained without dismounting the mounting plate 10.

The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention, and various modifications and changes may be made by those skilled in the art. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims

1. A sample introduction device, comprising:

a mounting plate (10) having a sample inlet (11);

a lifting unit (20), at least a part of the lifting unit (20) being arranged on the mounting plate (10) so as to be capable of lifting;

advance kind portion (30), it includes propelling movement piece (31) and actuating mechanism (32) to advance kind portion (30), propelling movement piece (31) is used for bearing the sample, actuating mechanism (32) with lift portion (20) are connected, lift portion (20) drive actuating mechanism (32) go up and down, actuating mechanism (32) with propelling movement piece (31) drive connection, in order to drive propelling movement piece (31) business turn over introduction port (11).

2. The sample feeding device according to claim 1, wherein the driving mechanism (32) comprises a connecting member (321), a link mechanism (322) and a first driving portion (323), the connecting member (321) and the first driving portion (323) are both installed on the lifting portion (20), one end of the link mechanism (322) is in driving connection with the pushing member (31), the other end of the link mechanism (322) is movably connected with the connecting member (321), and the first driving portion (323) is in driving connection with the link mechanism (322), wherein the link mechanism (322) drives the pushing member (31) to move in a translational motion.

3. The sampling device according to claim 2, wherein the link mechanism (322) comprises a first transmission rod (3221), a second transmission rod (3222), and a first rotation shaft (3223), a second rotation shaft (3224), a third rotation shaft (3225) and a fourth rotation shaft (3226) which are arranged in parallel, one end of the first transmission rod (3221) is fixedly connected with the first rotation shaft (3223), the first rotation shaft (3223) is hinged to the connecting member (321), the other end of the first transmission rod (3221) is hinged to the pushing member (31) through the second rotation shaft (3224), one end of the second transmission rod (3222) is hinged to the connecting member (321) through the third rotation shaft (3225), the other end of the second transmission rod (3222) is hinged to the pushing member (31) through the fourth rotation shaft (3226), and the first driving portion (323) is drivingly connected to the first rotation shaft (3223).

4. The sample feeding device according to claim 3, wherein the pushing member (31) comprises a first block body (311), a second block body (312), a third block body (313) and a pushing plate (314), two sides of the second block body (312) are respectively connected with the first block body (311) and the third block body (313), the pushing plate (314) is connected with the second block body (312), the pushing plate (314) is used for carrying a sample, the second rotating shaft (3224) sequentially passes through the first block body (311), the second block body (312) and the third block body (313), the first rotating shafts (3221) are two, the two first rotating shafts (3221) are respectively located between the first block body (311) and the second block body (312) and hinged with the second rotating shaft (3224), and the fourth rotating shaft (3226) passes through the first block body (311) and the third block body (313), and the second rotating shaft (3222) is located between the third block body (313) and the fourth block body (3226).

5. The sample feeding device according to claim 3, wherein the first driving part (323) comprises a first driving motor (3231) and a first conveyor belt, the first driving motor (3231) is mounted on the lifting part (20), an output shaft of the first driving motor (3231) is connected with the first rotating shaft (3223) through the first conveyor belt, and an output shaft of the first driving motor (3231) drives the first conveyor belt to rotate.

6. The sample injection apparatus according to claim 2, wherein the lifting portion (20) comprises a sliding member (21), a second driving portion (22) and two guide rails (23) vertically disposed at two sides of the sample injection port (11), both of the guide rails (23) are connected to the mounting plate (10), the sliding member (21) and both of the guide rails (23) are in sliding fit, the second driving portion (22) is connected to the sliding member (21), the second driving portion (22) drives the sliding member (21) to move up and down, the connecting member (321) and the first driving portion (323) are both mounted on the sliding member (21), wherein the sliding member (21) can block or avoid the sample injection port (11).

7. The sample injection apparatus according to claim 6, wherein the sliding member (21) comprises a supporting plate (211) and two sliding blocks (212), two ends of the supporting plate (211) are respectively connected with the two sliding blocks (212), the two sliding blocks (212) are respectively in sliding fit with the two guide rails (23), the second driving portion (22) is in driving connection with at least one of the sliding blocks (212), and the connecting member (321) is connected with the supporting plate (211).

8. The sample feeding device as claimed in claim 7, wherein the second driving part (22) comprises a second driving motor (221), a second conveyor belt (222) and a fixing member, the second driving motor (221) is mounted on the mounting plate (10), the second conveyor belt (222) is connected with the slide block (212) through the fixing member, and an output shaft of the second driving motor (221) drives the second conveyor belt (222) to rotate.

9. The sample introduction device according to claim 7, wherein the support plate (211) comprises a plate body (2111) and a placement frame (2112) which are connected with each other, two ends of the plate body (2111) are respectively connected with the two sliders (212), the placement frame (2112) is located above the connecting piece (321), the placement frame (2112) is used for supporting the pushing piece (31), the placement frame (2112) is provided with an avoidance port, and the link mechanism (322) passes through the avoidance port.

10. A liquid chromatograph, characterized in that, the liquid chromatograph includes a main structure (40) and the sample introduction device of any of claims 1 to 9, the sample introduction device is detachably mounted on a side wall of the main structure (40), the main structure (40) has a detection cavity, the detection cavity is communicated with a sample inlet (11) of the sample introduction device, and a push member (31) of the sample introduction device is used for conveying a sample to the detection cavity.