CN217628395U

CN217628395U - Be applicable to miniature bioreactor temperature regulating device

Info

Publication number: CN217628395U
Application number: CN202220823791.8U
Authority: CN
Inventors: 陈连方; 包磊
Original assignee: Jiangsu Connecticut Biological Technology Co ltd
Current assignee: Jiangsu Connecticut Biological Technology Co ltd
Priority date: 2022-04-11
Filing date: 2022-04-11
Publication date: 2022-10-21
Anticipated expiration: 2032-04-11

Abstract

The utility model discloses a miniature bioreactor technical field's a be applicable to miniature bioreactor temperature regulating device, which comprises a housin, the spout has all been seted up to the upper surface both sides of casing, the reaction seat is installed to the inside top central point of casing, L type splint are all installed to the both sides outer wall top and the below of reaction seat, and is rational in infrastructure, the utility model discloses a be equipped with electric heating wire and temperature control mechanism, install electric heating wire in the inside of reaction seat to carry out the circular telegram and handle, make the retort put into the reaction seat and carry out the intensification processing, through electric heating wire voltage control, thereby reach and carry out the intensification control to the retort, through being equipped with temperature control mechanism, establish temperature control mechanism into two sets ofly to with two sets of both sides of installing at the reaction seat, utilize the paler subsides on the temperature control mechanism, collocation electric motor to reach and cool down the processing to the retort in the reaction seat, effectually improved miniature bioreactor accuse temperature effect and efficiency.

Description

Be applicable to miniature bioreactor temperature regulating device

Technical Field

The utility model relates to a miniature bioreactor technical field specifically is a be applicable to miniature bioreactor temperature regulating device.

Background

A bioreactor is a device for culturing microorganisms/mammalian cells, and needs temperature regulation according to the growth condition of the microorganisms/mammalian cells in the bioreactor during use. The traditional bioreactor adopts a water jacket mode for controlling the temperature, namely the temperature of materials in a tank is controlled by adjusting the temperature of circulating water in a jacket of the bioreactor. The mode can realize accurate control of the temperature in the tank, but cannot realize rapid rise and fall of the temperature in the tank. In addition, the mode needs an external water source, which brings certain restriction to the installation and use of the equipment.

The existing temperature control device of the miniature bioreactor has the following defects: because the temperature regulating device structure is comparatively traditional, and the temperature control effect is poor, and the temperature intensification cooling effect is poor, and then leads to the microorganism to receive temperature variation's influence easily, causes the condition emergence of necrosis or the damage of different degree.

Therefore, it is necessary to develop a temperature control device suitable for a micro bioreactor.

SUMMERY OF THE UTILITY MODEL

An object of the utility model is to provide a be applicable to miniature bioreactor temperature regulating device, through being equipped with electric heating wire and temperature control mechanism, install electric heating wire in the inside of reaction seat, and carry out the circular telegram and handle, make the retort put into the reaction seat and carry out the intensification processing, through to electric heating wire voltage control, thereby reach and carry out the intensification control to the retort, through being equipped with temperature control mechanism, establish temperature control mechanism into two sets ofly, and with two sets of both sides of installing at the reaction seat, utilize the paler subsides on the temperature control mechanism, collocation electric motor, thereby reach the retort to the reaction seat in and cool down the processing, the effectual miniature bioreactor temperature control effect and the efficiency that have improved, with the problem that the miniature bioreactor temperature control effect and the efficiency difference are put forward in solving above-mentioned background art.

In order to achieve the above object, the utility model provides a following technical scheme: a temperature control device suitable for a miniature bioreactor comprises a shell, wherein sliding grooves are formed in two sides of the upper surface of the shell, a reaction seat is installed in the center of the top end in the shell, L-shaped clamping plates are installed above and below the outer walls of two sides of the reaction seat, a reaction tank is installed in the reaction seat, annular clamping plates are installed on two sides of the top of the shell, and temperature control mechanisms are installed on the outer walls of two sides of the reaction seat;

the temperature control mechanism comprises a cooling part and a heat dissipation part, the cooling part is connected with the L-shaped clamping plate, the heat dissipation part is connected with the cooling part, the cooling part comprises a fixing plate, one outer wall of one side of the fixing plate is fixedly connected with the inner wall of one side of the shell, the heat dissipation part comprises an L-shaped support, and one outer wall of one side of the L-shaped support is fixedly connected with the outer wall of the other side of the fixing plate.

Preferably, the access panel is installed to the preceding terminal surface of casing, the ventilating board is all installed to the preceding terminal surface both sides of access panel.

Preferably, the outer wall of retort and the inner wall sliding connection of reaction seat, the mounting bracket is installed to the bottom of reaction seat, the through-hole has all been seted up to the upper surface central point of mounting bracket.

Preferably, the bottom both sides of mounting bracket all are provided with the electricity connection seat, and are two sets of install the protection casing between the relative one side of electricity connection seat, the inside of protection casing is provided with electric heating wire.

Preferably, the slider is installed to bottom one side of annular splint, the outer wall of slider and the inner wall sliding connection of spout, spacing post is installed to one side outer wall of slider, the mounting panel is installed to outer wall one side of spacing post, the inside at the spout is fixed to the mounting panel, the surperficial central point of mounting panel puts and has seted up the mounting hole, the pore wall of mounting hole and the outer wall sliding connection of spacing post.

Preferably, the limiting plate is installed to the one end of spacing post, the outer wall opposite side of spacing post is provided with pressure spring, pressure spring is located between mounting panel and the slider.

Preferably, a radiator is installed above the outer wall of one side of the fixing plate, a peltier is installed on the outer wall of one side of the radiator, the outer wall of the peltier is in sliding connection with the inner wall of the L-shaped clamping plate, and silicone adhesive is arranged between the radiator and the peltier.

Preferably, an electric motor is installed at the bottom of the L-shaped support, an output shaft on the electric motor is fixedly connected with one end of the rotating shaft through a coupler, and the other end of the rotating shaft penetrates through the L-shaped support and is fixedly connected with the outer wall of one side of the radiating fan.

Compared with the prior art, the beneficial effects of the utility model are that:

through being equipped with electric heating wire and temperature control mechanism, install electric heating wire in the inside of reaction seat, and carry out the circular telegram and handle, make the retort put into the reaction seat and carry out the intensification processing, through electric heating wire voltage control, thereby reach and carry out intensification control to the retort, through being equipped with temperature control mechanism, establish temperature control mechanism into two sets ofly, and install two sets of both sides at the reaction seat, utilize the paler subsides on the temperature control mechanism, collocation electric motor, thereby reach and cool down the processing to the retort in the reaction seat, the effectual miniature bioreactor accuse temperature effect and the efficiency that have improved.

Drawings

FIG. 1 is a front sectional view of the present invention;

fig. 2 is a front view provided by the present invention;

fig. 3 is an enlarged view of the structure at a in fig. 1 according to the present invention;

FIG. 4 is a front sectional view of the temperature control mechanism provided by the present invention;

fig. 5 is a perspective view of the mounting bracket structure provided by the present invention.

In the figure: 1. a housing; 101. a chute; 102. an access panel; 103. a ventilation board; 2. a reaction seat; 201. an L-shaped splint; 202. a reaction tank; 203. a mounting frame; 204. a through hole; 205. an electrical connection base; 206. a protective cover; 207. an electric heating wire; 3. an annular splint; 301. a slider; 302. mounting a plate; 303. mounting holes; 304. A limiting column; 305. a limiting plate; 306. a compression spring; 4. a temperature control mechanism; 401. a fixing plate; 402. a heat sink; 403. a Peltier; 404. silicone gum; 405. an L-shaped bracket; 406. an electric motor; 407. a coupling; 408. a rotating shaft; 409. a heat dissipation fan.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.

The utility model provides a following technical scheme: a temperature control device suitable for a micro bioreactor can effectively improve the temperature control effect and efficiency of the micro bioreactor in the using process, and is additionally provided with an electric heating wire 207 and a temperature control mechanism 4, please refer to fig. 1-5, which comprises a shell 1, wherein two sides of the upper surface of the shell 1 are respectively provided with a chute 101, the front end surface of the shell 1 is provided with an access panel 102, two sides of the front end surface of the access panel 102 are respectively provided with a ventilating panel 103, so that the ventilating panel 103 ventilates the air in the shell 1, the central position of the top end in the shell 1 is provided with a reaction seat 2, the upper part and the lower part of the outer walls at two sides of the reaction seat 2 are respectively provided with an L-shaped clamping plate 201, the reaction seat 2 is internally provided with a reaction tank 202, the outer wall of the reaction tank 202 is slidably connected with the inner wall of the reaction seat 2, so that the reaction tank 202 is placed in the reaction seat 2 for subsequent temperature control operation, the bottom of the reaction seat 2 is provided with an installation frame 203, the center of the upper surface of the mounting rack 203 is provided with through holes 204, both sides of the bottom of the mounting rack 203 are provided with electric sockets 205, a protective cover 206 is arranged between two opposite sides of the two groups of electric sockets 205, an electric heating wire 207 is arranged in the protective cover 206, the electric sockets 205 are electrified to heat the electric heating wire 207 so as to achieve the heating effect, the surface of the mounting rack 203 is provided with the through holes 204 and is arranged under the reaction seat 2 so as to heat the electric heating wire 207, the temperature of the micro organisms in the reaction tank 202 can be raised, the temperature of the reaction tank 202 can be effectively controlled by controlling the voltage, both sides of the top of the shell 1 are provided with annular clamping plates 3, one side of the bottom of the annular clamping plates 3 is provided with sliding blocks 301, the outer walls of the sliding blocks 301 are connected with the inner walls of the sliding grooves 101 in a sliding manner, so that the annular clamping plates 3 can slide left and right on the shell 1, a limiting column 304 is installed on the outer wall of one side of the sliding block 301, a mounting plate 302 is installed on one side of the outer wall of the limiting column 304, the mounting plate 302 is fixed inside the sliding groove 101, a mounting hole 303 is formed in the center of the surface of the mounting plate 302, the hole wall of the mounting hole 303 is in sliding connection with the outer wall of the limiting column 304, the limiting column 304 slides left and right on the mounting plate 302, a limiting plate 305 is installed at one end of the limiting column 304, the limiting plate 305 limits the limiting column 304 and prevents the limiting column from being separated from the mounting plate 302, a compression spring 306 is arranged on the other side of the outer wall of the limiting column 304 and is located between the mounting plate 302 and the sliding block 301, the reaction tank 202 is placed in the reaction seat 2 by utilizing the elastic compression effect of the compression spring 306, and is elastically clamped by the annular clamping plate 3 and the compression spring 306, so that the stability of the reaction tank 202 is improved, the situation that the reaction tank 202 is prone to shake is reduced, and temperature control mechanisms 4 are installed on the outer walls of the two sides of the reaction seat 2;

the temperature control mechanism 4 comprises a cooling part and a heat dissipation part, the cooling part is connected with the L-shaped clamp plate 201, the heat dissipation part is connected with the cooling part, the cooling part comprises a fixing plate 401, one outer wall of one side of the fixing plate 401 is fixedly connected with the inner wall of one side of the shell 1, a heat radiator 402 is installed above the outer wall of one side of the fixing plate 401, heat generated in the working process of machinery or other appliances is timely transferred by the heat radiator 402 so as to avoid influencing the normal working of the machinery or other appliances, a Peltier 403 is installed on the outer wall of one side of the heat radiator 402, the outer wall of the Peltier 403 is in sliding connection with the inner wall of the L-shaped clamp plate 201, silicone glue 404 is arranged between the heat radiator 402 and the Peltier 403, the Peltier 403 is installed in the L-shaped clamp plate 201 on the reaction seat 2 in a sliding manner, and the silicone glue 404 is coated between the heat radiator 402, the Peltier 403 is a thermoelectric semiconductor refrigerating device and is matched with a radiator 402, so that the micro organisms in the reaction tank 202 are quickly cooled, the radiating component comprises an L-shaped support 405, the outer wall of one side of the L-shaped support 405 is fixedly connected with the outer wall of the other side of a fixing plate 401, an electric motor 406 is installed at the bottom of the L-shaped support 405, an output shaft of the electric motor 406 is fixedly connected with one end of a rotating shaft 408 through a coupler 407, the electric motor 406 drives the rotating shaft 408 to rotate forwards or backwards, the other end of the rotating shaft 408 penetrates through the L-shaped support 405 to be fixedly connected with the outer wall of one side of a radiating fan 409, the radiating fan 409 is arranged right below radiating fins on the radiator 402, the rotating shaft 408 is driven to rotate at a high speed, the radiating fan 409 is driven to radiate the radiating fins on the radiator 402, and the cooling treatment of the reaction tank 202 is accelerated.

The working principle is as follows: when the utility model is used, the reaction seat 2 is arranged inside the shell 1, the reaction tank 202 is placed in the reaction seat 2 for subsequent temperature control operation, the bottom of the mounting frame 203 is provided with two corresponding groups of electric connecting seats 205, an electric heating wire 207 is arranged between the two groups of electric connecting seats, the electric connecting seats 205 are electrified to heat the electric heating wire 207, the heating effect is achieved, the surface of the mounting frame 203 is provided with through holes 204 and is arranged under the reaction seat 2, the electric heating wire 207 is heated, the temperature of the microorganism in the reaction tank 202 can be raised, the temperature of the reaction tank 202 can be effectively controlled by controlling the voltage, the slide block 301 on the annular clamp plate 3 is arranged in the chute 101 on the shell 1 and is connected with the slide block, the annular clamp plate 3 slides left and right on the shell 1, the mounting plate 302 is arranged in the chute 101, the reaction tank 202 is placed in the reaction seat 2 by arranging the compression spring 306 on the outer wall of the limiting column 304, the compression spring 306 has an elastic compression effect, the reaction tank 202 is placed in the reaction seat 2, the annular clamping plate 3 is matched with the compression spring 306 to carry out elastic clamping treatment, so that the stability of the reaction tank 202 is improved, the situation that the reaction tank 202 is easy to shake is reduced, two groups of fixing plates 401 on the temperature control mechanism 4 are respectively arranged on the inner wall of the shell 1, the radiator 402 is arranged on the fixing plates 401, and the heat generated in the working process of machinery or other appliances is timely transferred by the radiator 402, the Peltier 403 is installed in the L-shaped clamp plate 201 on the reaction seat 2 in a sliding mode, silicone glue 404 is coated between the Peltier 403 and the radiator 402, the Peltier 403 is used as a thermoelectric semiconductor refrigerating device and is matched with the radiator 402, so that the micro-organisms in the reaction tank 202 are quickly cooled, the electric motor 406 is fixed on the fixing plate 401 through the L-shaped support 405, the rotating shaft 408 is installed on the output shaft of the electric motor 406 through the coupling 407, the rotating shaft 408 is driven by the electric motor 406 to rotate forwards or backwards, the radiating fan 409 is installed at one end of the rotating shaft 408, and the radiating fan 409 is arranged under the radiating fins on the radiator 402, so that the rotating shaft 408 rotates at a high speed, the radiating fan 409 is driven to carry out radiating treatment on the radiating fins on the radiator 402, the cooling treatment on the reaction tank 202 is accelerated, and the temperature control effect and efficiency of the micro-bioreactor are effectively improved.

While the invention has been described above with reference to an embodiment, various modifications may be made and equivalents may be substituted for elements thereof without departing from the scope of the invention. In particular, as long as there is no structural conflict, the various features of the disclosed embodiments of the present invention can be used in any combination with each other, and the description of such combinations is not exhaustive in the present specification only for the sake of brevity and resource conservation. Therefore, it is intended that the invention not be limited to the particular embodiments disclosed, but that the invention will include all embodiments falling within the scope of the appended claims.

Claims

1. The utility model provides a be applicable to miniature bioreactor temperature regulating device, includes casing (1), spout (101) have all been seted up to the upper surface both sides of casing (1), the inside top central point of casing (1) puts and installs reaction seat (2), L type splint (201) are all installed to the both sides outer wall top and the below of reaction seat (2), the internally mounted of reaction seat (2) has retort (202), annular splint (3), its characterized in that are all installed to the top both sides of casing (1): the outer walls of the two sides of the reaction seat (2) are respectively provided with a temperature control mechanism (4);

temperature-controlled mechanism (4) are including cooling part and heat dissipation part, cooling part is connected with L type splint (201), heat dissipation part is connected with cooling part, cooling part includes fixed plate (401), one side outer wall of fixed plate (401) and one side inner wall fixed connection of casing (1), heat dissipation part includes L type support (405), one side outer wall of L type support (405) and the opposite side outer wall fixed connection of fixed plate (401), radiator (402) are installed to one side outer wall top of fixed plate (401), peltier (403) are installed to one side outer wall of radiator (402), the outer wall of Peltier (403) and the inner wall sliding connection of L type splint (201), be provided with silicone gum (404) between radiator (402) and Peltier (403), electric motor (406) are installed to the bottom of L type support (405), the output shaft on electric motor (406) passes through shaft coupling (407) and the one end fixed connection of pivot (408), the other end of pivot (408) runs through one side of L type support (405) and heat dissipation fixed connection of fan (409).

2. The device according to claim 1, wherein the temperature control device comprises: an access panel (102) is installed on the front end face of the shell (1), and ventilating plates (103) are installed on two sides of the front end face of the access panel (102).

3. The device according to claim 1, wherein the temperature control device comprises: the outer wall of retort (202) and the inner wall sliding connection of reaction seat (2), mounting bracket (203) is installed to the bottom of reaction seat (2), through-hole (204) have all been seted up to the upper surface central point of mounting bracket (203).

4. The temperature control device for a micro-bioreactor according to claim 3, wherein: the bottom both sides of mounting bracket (203) all are provided with electricity connection seat (205), and are two sets of install protection casing (206) between the relative one side of electricity connection seat (205), the inside of protection casing (206) is provided with electric heating wire (207).

5. The device according to claim 1, wherein the temperature control device comprises: slider (301) are installed to bottom one side of annular splint (3), the outer wall of slider (301) and the inner wall sliding connection of spout (101), spacing post (304) are installed to one side outer wall of slider (301), mounting panel (302) are installed to outer wall one side of spacing post (304), the inside at spout (101) is fixed in mounting panel (302), mounting hole (303) have been seted up to the surperficial central point of mounting panel (302), the pore wall of mounting hole (303) and the outer wall sliding connection of spacing post (304).

6. The device according to claim 5, wherein the temperature control device comprises: limiting plate (305) are installed to the one end of spacing post (304), the outer wall opposite side of spacing post (304) is provided with pressure spring (306), pressure spring (306) are located between mounting panel (302) and slider (301).