CN217611384U - Multi-wavelength multi-channel laser system for neurosurgical thermal ablation - Google Patents

Abstract

The utility model provides a multi-wavelength multi-channel laser system for neurosurgery heat ablation, which comprises a magnetic resonance guide unit, a laser ablation unit and an optical fiber catheter unit; the laser ablation unit is used for generating an operation path and an operation scheme before an operation, and regulating and controlling a plurality of laser modules and cooling modules in real time during the operation to realize accurate ablation of tissues, and the optical fiber catheter unit is provided with a plurality of ablation channels and can realize ablation of tumors in any scale; the utility model discloses both can adopt the treatment scheme of multi-wavelength multichannel, can use high power single wavelength to carry out accurate conformal ablation with the single channel scheme to regular or irregular tumour again, greatly increased laser thermotherapy's application scope and use flexibility.

Description

Multi-wavelength multi-channel laser system for neurosurgical thermal ablation

Technical Field

The utility model belongs to the laser therapy field especially indicates a multi-wavelength multichannel laser system that is used for neurosurgery heat to melt.

Background

The laser medical treatment technology is that laser emitted by a laser is irradiated on a tissue needing treatment through a medical optical fiber, and heat effect or shock wave generated by the laser is used for heat coagulation, vaporization or cutting treatment of gravels or soft tissues. The laser medical treatment technology is widely applied because of short operation time and small wound in cell thermal damage, lithotripsy and soft tissue cutting treatment. In recent years, laser Interstitial Thermal Therapy (LITT), which is a laser-based interstitial hyperthermia (hereinafter abbreviated as LITT), is guided by Magnetic Resonance Imaging (MRI) focused by medical workers at home and abroad, and is translated into "laser-technology-based interstitial hyperthermia", which is abbreviated as laser hyperthermia, and is applied to the thermal effect principle of laser. The laser interstitial thermotherapy is a percutaneous minimally invasive operation guided by three-dimensional directional magnetic resonance imaging, and laser acts on a target point through optical fiber transmission so as to selectively ablate diseased tissues. That is to say, the optical energy is transmitted to the focal tissue through the optical fiber in the operation for accurate irradiation, and the photothermal conversion is realized, so that the focal tissue is thermally coagulated and denatured due to the temperature rise of the focal region, and the treatment purpose is achieved.

LITT is considered a less invasive technique than traditional craniotomy, and shows encouraging results in the treatment of gliomas, brain metastases, radionecrosis and epilepsy, providing a safer alternative to patients who cannot surgically remove the lesion and who are not candidates for surgery or who have otherwise failed standard treatment regimens. However, this LITT technique has its specific indications, which are currently only applicable to small, regular lesions. In other words, there are still some limitations on lesion size and shape when using the LITT technique. For example, a single treatment can be generally administered for brain tumors less than 3cm in diameter; whereas for lesions with a diameter of 3cm or more, ablation of the entire brain tumor is required through multiple tracks.

The limitation is caused by the fact that most of the existing LITT devices or systems only include a laser capable of emitting a single wavelength and an optical fiber matched with the laser, that is, the existing LITT devices only can emit laser with a specific wavelength, have a single light source, and can only perform single-channel ablation operation. When the focus with the diameter more than or equal to 3cm or the focus with irregular shape is treated, the optical fiber needs to be repeatedly plugged and pulled so as to achieve the purpose of multi-track ablation of the whole focus. For example, a lesion with an irregular shape and a diameter of more than or equal to 3cm is ablated, 2 ablation tracks are planned in the preoperative planning stage, and when the existing single-wavelength single-channel LITT equipment is used for ablating the tissue, treatment operation steps such as skull perforation, optical fiber puncture and laser ablation need to be performed according to the first ablation track. However, when the ablation is performed along the second ablation track, the operation must be interrupted first, and after the medical care worker enters the magnetic resonance room or pushes the patient back to the operating room to insert the ablation optical fiber into the head of the patient according to the new ablation track, the second ablation operation is performed, and such operations of interrupting the operation and repeatedly entering the sterile operation environment will undoubtedly increase the operation time and the infection risk of the patient, which is an operation that should be avoided as much as possible in the operation. Secondly, the ablation range of the single-wavelength laser is very fixed, and the ablation of a large focus is certainly highly dependent on the precision of each optical fiber puncture position if the ablation is completed in a multi-track and multi-ablation mode, so that incomplete ablation is possibly caused if the optical fiber puncture position is slightly deviated, and even unnecessary remedial puncture and ablation steps are additionally added. Therefore, the single-wavelength single-channel LITT equipment has great limitation on the selection of the focus, low flexibility in planning of an operation scheme, and the ablation planning of a large focus too depends on the precision of optical fiber puncture, so that the development and popularization of the LITT technology are greatly limited.

In order to solve the above problems, we developed a multi-wavelength multi-channel LITT device or system to treat multiple regular focal tissues at one time by means of different heat loss to the tissues and different ablation ranges of different wavelengths. However, due to various practical technical conditions, the multi-wavelength laser is rarely used. To meet the needs of medical applications, particularly in the field of medical laser applications, few manufacturers have available high power, multiple wavelength laser treatment devices.

Therefore, it is desirable to provide a new technical solution to solve the above problems.

SUMMERY OF THE UTILITY MODEL

An object of the utility model is to provide an applicable multi-wavelength multichannel laser system who melts in neurosurgery heat of focus tissue, it includes two at least fiber conduit for melting, and each fiber conduit corresponds respectively and is connected with laser generator, each laser generator can launch the laser of different or the same wavelength. Therefore, the utility model discloses both can adopt the treatment scheme of multi-wavelength multichannel, can use again the high power single wavelength to melt regular or irregular tumour's accurate shape with the single channel scheme, greatly increased LITT's application scope and use flexibility.

The technical means adopted by the utility model are as follows.

The utility model discloses a multi-wavelength multichannel laser system includes: (1) a magnetic resonance guidance unit: it comprises an MRI device and an MRI control center; the MRI control center is used for processing at least one of the following processes: data acquisition, data processing, image reconstruction, image display and image storage.

(2) And the laser ablation unit: the laser ablation unit is connected with the magnetic resonance guide unit and comprises a control host; the control host machine completes at least one of the following according to the digital image information of the patient: profiling, 3D modeling, generating a surgical plan of the patient; the control host fuses the digital image information through an MRI temperature imaging technology to generate a real-time temperature image, and the real-time temperature image is displayed on a human-computer interaction module. The laser ablation unit also comprises a laser module connected with the control host, and the laser module is provided with N laser devices; the control host synchronously or asynchronously regulates and controls partial or all laser working parameters in the N laser devices according to the operation scheme and the real-time temperature image; and (d).

(3) The optical fiber conduit unit: which is connected with the laser ablation unit, and the optical fiber catheter unit is provided with M optical fiber catheters for ablation.

Further, N is 2 or more.

Further, M is 1 or more.

Further, when N is greater than or equal to 2 and M is equal to N, each fiber optic catheter is connected with each laser device in a one-to-one correspondence manner to form N ablation channels; and/or the laser module is provided with N laser devices, wherein N is at least 2; the optical fiber conduit unit is provided with M optical fiber conduits, and M is at least 1; the N laser devices are respectively connected with each optical fiber conduit; and/or the laser module is provided with N laser devices, wherein N is at least 1; the optical fiber conduit unit is provided with M optical fiber conduits, and M is at least 2; m fiber optic conduits are respectively connected with each laser device.

Further, each laser device emits laser light with at least one wavelength; and/or the N laser devices all emit laser with the same wavelength; and/or one part of the N laser devices emits laser with a first wavelength, and the other part of the N laser devices emits laser with a second wavelength, wherein the second wavelength is different from the first wavelength.

Further, when N is equal to 2, the laser module includes a first laser device and a second laser device; and the control host synchronously or asynchronously regulates and controls the laser working parameters of the first laser device and the second laser device according to the operation scheme and the real-time temperature image. Meanwhile, the optical fiber conduit unit comprises a first optical fiber conduit and a second optical fiber conduit; the first optical fiber conduit is connected with the first laser device, and the second optical fiber conduit is connected with the second laser device.

Furthermore, at least one of the first optical fiber conduit and the second optical fiber conduit is provided with a temperature measuring optical fiber, and the temperature measuring optical fiber is used for detecting the real-time temperature of the optical fiber conduit unit and the tissues around the optical fiber conduit unit; the temperature measuring optical fiber is connected with an optical fiber temperature measuring module in the laser ablation unit; the optical fiber temperature measurement module is connected with a temperature correction module in the control host, and the temperature correction module is used for correcting the temperature.

Further, the temperature correction module is to perform at least the following: and taking the real-time temperature value of the tissue acquired by the optical fiber temperature measurement module in real time as the reference temperature measurement value of the magnetic resonance guide unit, and feeding back a correction temperature image to the control host. The corrected temperature image is generated by the magnetic resonance guide unit based on the reference temperature measurement value, and the corrected temperature image fed back to the control host is used for replacing the real-time temperature image.

Further, the control host is used for regulating and controlling the laser module in real time according to the corrected temperature image.

Further, the first laser device generates laser with a first wavelength, and the second laser device generates laser with a second wavelength; the first wavelength and the second wavelength are the same or different; the laser module is provided with a first laser device for generating laser with the first wavelength and a second laser device for generating laser with the second wavelength.

Further, the first wavelength is 980nm, and the second wavelength is 1064nm.

Further, the laser operating parameters include at least one of: laser output power, light emitting time of laser and light emitting mode of laser.

Further, the laser module is also provided with a cooling module, and the cooling module is connected with the control host and the optical fiber conduit unit; the control host controls the operation of the cooling module, and the cooling module cools the optical fiber conduit unit and the tissues around the optical fiber conduit unit by driving and controlling the flow of the cooling medium.

Further, the optical fiber conduit unit is provided with the first optical fiber conduit and the second optical fiber conduit which have the same structure; wherein, the optical fiber conduit bag comprises an optical fiber, a cooling inner pipe and a cooling outer pipe.

Furthermore, the laser ablation unit comprises a control host, a human-computer interaction module, a laser module, a cooling module, a power supply module, an optical fiber temperature measurement module and an effect evaluation module.

Further, the power module is provided with at least one UPS device and at least one power distribution control board; the electric energy input end of the laser ablation unit is connected with a power line; one end of the power line is connected with a commercial power end, and the other end of the power line is connected with the electric energy input end of the UPS equipment.

Furthermore, the power distribution control board comprises a plurality of connecting terminals, a built-in independent switch power supply and a latching relay; the latching relay is electrically connected with a PCS-1 channel, and the PCS-1 channel is used for being electrically connected with the emergency stop switch and the key switch; the power distribution control board also includes a PCS-2 channel connected to the cooling module.

Further, the effect evaluation module performs real-time estimation on the tissue ablation condition in the operation by using an Arrhenius model or a CEM43 model;

the control host generates a regulation and control instruction of at least one of the following in real time according to the ablation progress fed back by the effect evaluation module: laser output power, light-emitting time, light-emitting mode and coolant flow rate.

Furthermore, the human-computer interaction module comprises a first touch screen, a second touch screen, a third touch screen, an emergency stop switch, a pedal controller, an entity key and an indicator light.

Furthermore, the first touch screen and the second touch screen are connected with an industrial personal computer of the control host, and the third touch screen is connected with a main board of the control host. The first touch screen comprises an MRI real-time temperature monitoring interface and an ablation area evaluation interface; the touch screen comprises a first laser device parameter interface, a second laser device parameter interface and a cooling module parameter interface; the third touch screen and the second touch screen display the same or different interface contents.

Further, the control host monitors safe operation parameters of the laser module, the optical fiber temperature measurement module and the cooling module in real time; when the operation parameter exceeds a safe operation threshold value, the control host computer enables the laser module and/or the cooling module to stop emitting light.

Further, the multi-wavelength multi-channel laser system further includes: software, wherein the software performs at least one of the following functions: generating a surgical plan, wherein the surgical plan contains information corresponding to each of the N laser devices, wherein the information includes at least one of: planning ablation area or volume, laser power used to achieve a predetermined ablation result, light extraction time, light extraction pattern, number of ablation channels required, cooling flow rate.

And real-time control, under the guidance of the magnetic resonance guidance unit, according to each laser device in the N laser devices, respectively according to the corresponding operation scheme and the correction temperature image, the working parameters of each laser device in a working state and the cooling module are regulated and controlled in real time, and ablation monitoring is carried out in real time.

Comparing and analyzing, namely comparing the information in the operation scheme corresponding to each laser device with the information of the laser device after operation, generating ablation result information according to the comparison result and displaying the ablation result information on the man-machine interaction module; wherein, the content of comparison includes the following: a planned ablation area or volume, and a post-operative actual ablation area or volume; the ablation result information at least comprises one of the following information: ablation area percentage, ablation volume percentage, and ablation area percentage before and after ablation.

Compared with the prior art, the utility model discloses borrow by ingenious structural design and reached following beneficial effect:

(1) The utility model is suitable for a regular or irregular tumour's accurate shape is conformed and is ablated, and is unrestricted to the diameter size and the shape of focus, and equipment availability is high, and application scope is wide, can carry out a plurality of operations of ablating simultaneously.

(2) The flexibility of the operation scheme is high, and a multi-wavelength and multi-channel ablation scheme and a high-power single-wavelength and single-channel ablation scheme can be adopted; and various working modes can be combined while different ablation schemes are adopted, so that different laser channels can be combined randomly.

(3) The utility model can realize the simultaneous treatment of a plurality of target spots through multi-channel output according to different characteristics of the focus; the operating mode of the multiple channels may be synchronous or asynchronous. The output wavelength may be selected from a single-wavelength output or a dual-wavelength alternate output or simultaneous output.

(4) Unique cooling system can direct adaptation normal saline bottle to have heating device and backflow to detect, can know cooling system whether normal operating.

(5) The multiple control system can be controlled by intraoperative software on the second touch screen and can also control the laser module and the cooling module by a lower computer system on the third touch screen, so that the system is more stable. And meanwhile, a keyboard and a mouse and entity operation keys are configured, so that the risk of failure of the touch screen is avoided.

(6) The fiber catheter system comprises a fiber catheter component for ablation and a fiber catheter fixing component, and can realize accurate guiding and positioning. The integrated control host system can perform preoperative planning and intraoperative control operation.

(7) The material attribute of temperature measurement optic fibre satisfies nuclear-magnetism compatible requirement, compares with current thermodetector, like the thermocouple and has higher temperature measurement precision and stability.

Drawings

Fig. 1 is a structural frame diagram of the multi-wavelength multi-channel laser system of the present invention.

Fig. 2 is a frame diagram illustrating an exemplary structure of the multi-wavelength multi-channel laser system of the present invention.

Fig. 3 is a diagram of two frames of an exemplary structure of the multi-wavelength multi-channel laser system of the present invention.

Fig. 4 is a three-frame diagram of an exemplary structure of the multi-wavelength multi-channel laser system of the present invention.

Fig. 5 is a schematic diagram of a connection relationship between the control host and the human-computer interaction module.

Fig. 6 is a schematic view of a cooling module structure.

FIG. 7 is a schematic diagram showing the connection relationship between the laser module, the cooling module and the fiber conduit.

Fig. 8 is a schematic diagram of the multi-wavelength multi-channel laser system of the present invention.

Fig. 9 is a schematic diagram of power distribution of a power module in a laser ablation unit.

Fig. 10A to 10H are schematic diagrams illustrating the correspondence between the laser module and the fiber optic conduit.

Fig. 11A to 11C are schematic diagrams of a ring fiber, a side-emitting fiber, and a dispersion fiber.

Description of the figure numbers:

magnetic resonance guidance unit 100

MRI apparatus 101

MRI control center 102

Laser ablation unit 200

Control host 201

Temperature correction module 2011

Industrial computer 2012

Host 2013

Laser module 202

Laser device 1 2021

Laser device II 2022

Cooling module one 2023

Cooling module II 2024

Human-computer interaction module 203

Touch screen I2031

Touch screen two 2032

Touch screen three 2033

Emergency stop switch 2034

Foot pedal controller 2035

Physical button 2036

Indicator light 2037

Power module 204

Key switch 205

Optical fiber temperature measurement module 206

Effect evaluation Module 207

Fiber optic catheter unit 300

Fiber optic conduit one 301

Optical fiber conduit two 302

Optical fiber 1

Inner pipe 2

Outer tube 3

Cold liquid inlet 4

Cold liquid outlet 5

Return chamber 6

The fastening assembly 7

Temperature measuring optical fiber 8

Light emitting part 9

Cooling liquid tank 10

Heater 101

Temperature sensor 102

Level sensor 103

Peristaltic pump 20

Inlet pipe 30

Return pipe 40

Waste liquid tank 50

A flow sensor 501.

Detailed Description

The utility model provides a multi-wavelength multichannel laser system for neurosurgery heat ablation, this multi-wavelength multichannel laser system can realize the treatment to many positions of focus simultaneously, and different positions can adopt different laser parameter. The multi-wavelength and multi-channel thermal ablation laser system solves the problem of limitation on the size and the shape of a tumor in the prior art, and truly realizes accurate conformal ablation on any regular or irregular tumor. Meanwhile, the multi-wavelength multi-channel laser system also provides an optical fiber temperature measurement module, the optical fiber temperature measurement module can monitor the temperature of the tissue in real time, the temperature measurement blank caused by the scanning interval of the MRI equipment is filled, the temperature measurement of the optical fiber temperature measurement module is rapid and accurate, and even under the condition that no cooling module is arranged, the multi-wavelength multi-channel laser system can realize accurate temperature measurement and ablation of the tissue.

The invention will be described in detail with reference to the drawings and specific embodiments, wherein the exemplary embodiments and the description are only used for explaining the invention, but not for limiting the invention. In addition, for better explanation the utility model discloses in the near-end be the one end that the optic fibre goes out the light portion and be close to the focus tissue, and the one end of keeping away from the focus tissue is the distal end promptly.

Please refer to fig. 1 and fig. 8, which are structural frame diagrams of the multi-wavelength multi-channel laser system of the present invention. The utility model provides a multi-wavelength multichannel laser system for neurosurgery heat is ablated, multi-wavelength multichannel laser system mainly contains magnetic resonance guide element 100, laser ablation unit 200 and fiber catheter unit 300.

Magnetic resonance guidance unit 100: the magnetic resonance guidance unit 100 is provided with an MRI apparatus 101 and an MRI control center 102, and the MRI apparatus 101 is connected to the MRI control center 102. The MRI apparatus 101 is used for monitoring medical information of a patient and tissues thereof and transmitting the medical information to the MRI control center 102. The MRI control center 102 is configured to perform at least one of the following processes: data acquisition, data processing, image reconstruction, image display and image storage.

Laser ablation unit 200: the laser ablation unit 200 is connected to the magnetic resonance guiding unit 100, and the laser ablation unit 200 includes a control host 201. The control host 201 completes at least one of the following according to the digital image information of the patient: profiling, 3D modeling, generating a surgical plan of the patient; the control host 201 fuses the digital image information through an MRI temperature imaging technology to generate a real-time temperature image, and displays the real-time temperature image on the human-computer interaction module 203; the digital image information includes, but is not limited to, CT images, magnetic resonance images. The laser ablation unit 200 further comprises a laser module 202 connected to the control host 201, wherein the laser module 202 is provided with N laser devices; the control host 201 synchronously or asynchronously regulates and controls the laser working parameters of the N laser devices according to the operation scheme and the real-time temperature image.

[ optical fiber conduit unit 300 ]: the fiber catheter unit 300 has N fiber catheters for ablation, and each fiber catheter is connected with each laser device in a one-to-one correspondence manner to form N ablation channels.

Further, in a preferred embodiment of the present invention, N is 2 or more.

When N is equal to 2, the laser module 202 includes a first laser device 2021 and a second laser device 2022; the control host 201 synchronously or asynchronously regulates and controls the laser working parameters of the first laser device 2021 and the second laser device 2022 according to the surgical plan and the real-time temperature image. Meanwhile, the fiber conduit unit 300 comprises a first fiber conduit 301 and a second fiber conduit 302; the first optical fiber conduit 301 is connected with the first laser device 2021, and the second optical fiber conduit 302 is connected with the second laser device 2022.

The laser working parameters at least comprise one of the following parameters: the laser light source comprises laser output power or light emitting time or a light emitting mode or any combination of the laser output power, the light emitting time and the light emitting mode.

Further, the core of the laser ablation unit 200 is that the first laser device 2021 generates laser light with a first wavelength, and the second laser device 2022 generates laser light with a second wavelength; the first wavelength and the second wavelength are the same or different.

Preferably, the first wavelength is 980nm and the second wavelength is 1064nm.

In summary, the multi-wavelength multi-channel laser system has a multi-wavelength laser module capable of synchronously or asynchronously emitting 980nm laser light and 1064nm laser light, and a first optical fiber catheter and a second optical fiber catheter for transmitting light energy and ablating are matched with the laser module. Based on this, a multi-wavelength multichannel laser system for neurosurgery heat is thawed to multi-wavelength, the technical scheme who melts the passageway more realize melting the accurate of arbitrary tumour, avoided prior art to great or the irregular tumour of shape must carry out the problem of reinsertion optic fibre many times, improved the practicality of equipment, provide nimble various scheme of melting for medical worker.

Based on the above basic embodiment, in another preferred embodiment of the present invention, the multi-wavelength multi-channel laser system for neurosurgical thermal ablation comprises a magnetic resonance guiding unit 100, a laser ablation unit 200, and a fiber catheter unit 300. Wherein the magnetic resonance guidance unit 100: it includes an MRI apparatus 101 and an MRI control center 102; the MRI control center 102 is configured to perform at least one of the following processes: data acquisition, data processing, image reconstruction, image display and image storage.

The laser ablation unit 200: which is connected with the magnetic resonance guiding unit 100, and the laser ablation unit 200 includes a control host 201; the control host 201 completes at least one of the following according to the digital image information of the patient: profiling, 3D modeling, generating a surgical plan of the patient; the control host 201 fuses the digital image information through an MRI temperature imaging technology to generate a real-time temperature image, and displays the real-time temperature image on the human-computer interaction module 203. The laser ablation unit 200 further comprises a laser module 202 connected to the control host 201, wherein the laser module 202 is provided with N laser devices; the control host 201 synchronously or asynchronously regulates and controls some or all laser working parameters in the N laser devices according to the operation scheme and the real-time temperature image.

Fiber conduit unit 300: which is connected to the laser ablation unit 200, and the fiber catheter unit 300 has M fiber catheters for ablation. Further, N is 2 or more, and/or M is 1 or more.

In order to achieve the purpose of ablating larger focal tissues at one time or completing multi-point ablation in the focal region at one time, in the preferred embodiment, a multi-channel ablation method is also provided. The flexible selectivity of the plurality of ablation channels to generate the number of the latter ablation channels is achieved based on the corresponding connection relationship between the laser module 202 and the fiber-optic catheter unit 300, including but not limited to the one-to-one connection between the laser module 202 and the fiber-optic catheter unit 300, i.e. the one-to-one connection form; it may also be a connection between a plurality of laser modules 202 and one fiber-optic conduit unit 300, i.e. a many-to-one connection; or a connection between one laser module 202 and a plurality of fiber-optic conduit units 300, i.e. a one-to-many connection form; it is also possible to have a connection between a plurality of said laser modules 202 and a plurality of said fibre-optic catheter units 300, i.e. a many-to-many connection. Of course, various flexible modes based on the corresponding connection relationship, or the flexible modes of the corresponding relationship performed by the number of the laser devices in the laser module 202 and the number of the optical fiber conduits in the optical fiber conduit unit 300, are all within the protection scope of the present invention. Only individual ones of the numerous corresponding connections are described below.

1. One form of the corresponding connection relationship.

Referring to fig. 10A, the laser module 202 is provided with N laser devices, and the fiber catheter unit 300 has M fiber catheters for ablation. Preferably, N is 2 or more, and M is 2 or more. When M is further equal to N, each of the fiber optic catheters is connected to each of the laser devices in a one-to-one correspondence manner, so as to form N (or M) ablation channels.

Another variation is shown in fig. 10B. As shown in fig. 10B, the laser ablation unit 200 is provided with at least 2 laser modules 202, and each laser module 202 is provided with at least one laser device therein. The number of the optical fiber conduits corresponding to the number of the laser devices at least is arranged in the optical fiber conduit unit 300, that is, at least 2 optical fiber conduits are arranged in the optical fiber conduit unit 300. Referring again to fig. 10B, a first laser device in the first laser module 202 is connected to the first fiber optic conduit; the second laser device in the second laser module 202 is connected with the second optical fiber conduit.

2. And the corresponding connection relationship is in two forms.

Referring to fig. 10C, the laser module 202 has N laser devices, where N is at least 2; the optical fiber conduit unit 300 is provided with M optical fiber conduits, wherein M is at least 1; the N laser devices are respectively connected with each optical fiber conduit. Further, as shown in fig. 10C, N is equal to 2 (including the first laser device and the second laser device), and M is equal to 3 (including the first optical fiber conduit, the second optical fiber conduit, and the third optical fiber conduit). Namely, the first laser device is simultaneously or non-simultaneously connected with a first optical fiber conduit, a second optical fiber conduit and a third optical fiber conduit; the first optical fiber conduit, the second optical fiber conduit and the third optical fiber conduit are connected with the second laser device at the same time or at different times.

As shown in fig. 10D, another alternative form is: the laser ablation unit 200 is provided with at least 2 laser modules 202, and at least one laser device is arranged in each laser module 202. The number of the optical fiber conduits, which is at least the same as or different from the number of the laser devices, is arranged in the optical fiber conduit unit 300. Fig. 10D shows an arrangement in which at least 2 of the fiber-optic tubes are provided in the fiber-optic tube unit 300. Therefore, the corresponding connection relationship is that the first laser device in the first laser module 202 is connected with the first optical fiber conduit and the second optical fiber conduit; the second laser device in the second laser module 202 is connected with the first optical fiber conduit and the second optical fiber conduit.

Furthermore, the corresponding connection relationship may also be the connection manner shown in fig. 10E, in this embodiment, the optical fiber conduit unit 300 is provided with two groups of optical fiber conduits, each group includes a first optical fiber conduit, a second optical fiber conduit and a third optical fiber conduit. That is, the first laser device in the first laser module 202 is connected with the first optical fiber conduit, the second optical fiber conduit and the third optical fiber conduit in the first group of optical fiber conduits at the same time or at different times; the second laser device in the second laser module 202 is connected with the first optical fiber conduit, the second optical fiber conduit and the third optical fiber conduit in the second group of optical fiber conduits at the same time or at different times.

3. And three forms of the corresponding connection relation.

Referring to fig. 10F, the laser module 202 has N laser devices, where N is at least 1; the optical fiber conduit unit 300 is provided with M optical fiber conduits, M is at least 2; m fiber optic conduits are respectively connected with each laser device. With reference to fig. 10F, the first laser device is connected to the first optical fiber conduit, and the second laser device is connected to the first optical fiber conduit.

Another form is as shown in fig. 10G, that is, a first laser device, a second laser device, and a third laser device are disposed in the laser module, and the fiber guide tube unit 300 is provided with a first fiber guide tube and a second fiber guide tube. The corresponding relation between the laser module and the optical fiber conduit unit is as follows: the first laser device is connected with a first optical fiber conduit and a second optical fiber conduit at the same time or at different times; the laser device II is connected with the optical fiber conduit I and the optical fiber conduit II at the same time or at different times; the laser device III is connected with the optical fiber conduit I and the optical fiber conduit II at the same time or at different times.

Shown in fig. 10H is another form of connection: the laser ablation unit 200 is at least provided with 2 laser modules 202, and each laser module 202 is provided with at least one laser device. The number of the optical fiber conduits at least equal to or different from the number of the laser devices is arranged in the optical fiber conduit unit 300. As shown in fig. 10H, at least a first fiber conduit and a second fiber conduit are disposed in the fiber conduit unit 300. Therefore, the corresponding connection relationship is that the first laser device in the first laser module 202 is connected with the first optical fiber conduit and the second optical fiber conduit; the second laser device in the second laser module 202 is connected with both the first optical fiber conduit and the second optical fiber conduit.

On the basis of the above embodiment, the surgical plan of the present invention includes N information corresponding to each of the laser devices, wherein the information includes at least one of the following: planning ablation area and/or ablation volume, laser power used for achieving a preset ablation result, laser light emitting time, light emitting mode, the number of required ablation channels (also the selection of the connection mode of a laser module and a fiber catheter), coolant flowing rate and fiber catheter insertion path planning; compared with the prior art, the method has more flexible selectivity and wide application range.

It is further preferred that each of the laser devices emits laser light of at least one wavelength, i.e. one laser device may be arranged to emit laser light of one wavelength, or one laser device may be arranged to emit laser light of 2 or more wavelengths of the same or different ranges.

Preferably, the number of the laser devices is N, and each laser device may be configured to emit laser light of only one wavelength. And/or one part of the N laser devices is set to emit laser light with a first wavelength only, and the other part of the N laser devices emits laser light with a second wavelength, wherein the second wavelength is different from the first wavelength.

Further preferably, as shown in fig. 11A to 11C, the optical fiber in the optical fiber conduit may be one of a ring fiber, a dispersion fiber and a side-emitting fiber. The ring-shaped optical fiber is a laser transmission optical fiber, and the front end light-emitting mode of the ring-shaped optical fiber is output along the whole circumference of the radial direction. A dispersion fiber is a laser delivery fiber whose front end light exit pattern will be output radially and axially over a predefined length all around. The side-emitting optical fiber is a laser transmission optical fiber, and the front light emitting mode of the side-emitting optical fiber is output along the radial side surface. The proximal end of the optical fiber (i.e., the end near the focal tissue is the proximal end) may also be configured as one of a beveled tip, a semi-circular tip, a spherical tip, a conical tip, and a chisel tip.

Of course, based on the design idea of the present invention, various embodiments can be obtained by further optimization, and the following description will be further explained with reference to the accompanying drawings.

The first embodiment is as follows: and (3) an optimization scheme about accurate temperature measurement design.

Referring to fig. 2, on the basis of the multi-wavelength multi-channel laser system, the first embodiment is improved in that the multi-wavelength multi-channel laser system has a temperature measurement function of the magnetic resonance guiding unit, and also has a function of detecting a tissue temperature in real time, so as to achieve dual-precise temperature measurement. Specifically, the first optical fiber conduit 301 and the second optical fiber conduit 302 have the same structure, and the first optical fiber conduit 301 is taken as an example for explanation: the optical fiber conduit I301 is provided with a temperature measuring optical fiber, and the connection relationship between the temperature measuring optical fiber 8 and the optical fiber conduit I301 includes but is not limited to adhesion, embedding arrangement and the like. Preferably, the temperature detecting heads of the temperature detecting optical fibers 8 are close to the light outlet part 9 of the first optical fiber conduit 301, and a plurality of temperature detecting heads can be arranged along the length direction of the first optical fiber conduit 301.

The temperature measurement optical fiber 8 is used for detecting and collecting real-time temperatures of the optical fiber conduit I301 where the temperature measurement optical fiber 8 is located and tissues around the optical fiber conduit I301, and transmitting data information of the real-time temperatures to the optical fiber temperature measurement module 206. The temperature measuring optical fiber 8 is connected with an optical fiber temperature measuring module 206 in the laser ablation unit 200; the optical fiber temperature measuring module 206 is connected with a temperature correction module 2011 in the control host 201. That is, in the optical fiber temperature measurement module 206, the collected optical signal is fed back to the optical signal decoder in real time, and after signal conversion, the temperature value is fed back to the temperature correction module 2011 in the control host 201.

At least the following will be done within the temperature correction module 2011: (1) directly using the real-time temperature value of the tissue acquired by the optical fiber temperature measurement module 206 in real time as the reference temperature measurement value of the magnetic resonance guiding unit 100; (2) based on the baseline thermometry value, the magnetic resonance guidance unit 100 will generate a corrected temperature image; (3) the temperature correction module 2011 feeds back image correction information to the control host 201, where the image correction information at least includes replacing the real-time temperature image with the corrected temperature image. The control host 201 regulates and controls the laser module 202 in real time according to the corrected temperature image.

Further, in the first embodiment, the control host 201 synchronously or asynchronously regulates and controls the laser output power, the light emitting time, the light emitting mode, and other working parameters of the first laser device 2021 and the second laser device 2022 according to the surgical plan and the corrected temperature map.

Further, the temperature measuring optical fiber 8 may also feed back a safety parameter condition of the system to the control host 201, and when the temperature data measured by the temperature measuring optical fiber 8 exceeds a safety threshold, the control host 201 may stop the operation of the laser module urgently.

Example two: and (3) optimizing the system temperature control design.

As shown in fig. 3, in order to further improve the precision of conformal ablation, on the basis of the first embodiment, the laser module 202 is further configured with a cooling module, and the cooling module is connected to both the control host 201 and the fiber catheter unit 300. The control host 201 controls the operation of the cooling module; the cooling module cools the optical fiber conduit unit 300 and the tissue around the optical fiber conduit unit 300 by driving and controlling the circulation flow of the cooling medium. The optical fiber conduit unit 300 has the first optical fiber conduit 301 and the second optical fiber conduit 302 with the same structure, and the first optical fiber conduit 301 is used for illustration: the first optical fiber conduit 301 comprises an optical fiber, a cooling inner tube and a cooling outer tube. The optical fiber is connected with the first laser device 2021; and a circulating inlet and outlet channel of a cooling medium consisting of the optical fiber, the cooling inner pipe and the cooling outer pipe is connected with the first cooling module.

The cooling module comprises a first cooling module 2023 and a second cooling module 2024 which have the same structure, wherein the first cooling module 2023 is used for cooling the first optical fiber conduit 301, and the second cooling module 2024 is used for cooling the second optical fiber conduit 302. Referring to fig. 6, the first cooling module 2023 includes a cooling liquid tank 10, a peristaltic pump 20, a water inlet pipe 30, a water return pipe 40, and a waste liquid tank 50; the cooling liquid tank 10 is further provided with a heater 101, a temperature sensor 102 and a liquid level sensor 103, and the water return pipe 40 is further provided with a flow sensor 501. Preferably, the first cooling module 2023 adopts a single-channel circulation system (i.e., no circulation pipeline is added between the waste liquid tank 50 and the cooling liquid tank 10), so as to prevent the occurrence of a circulation reflux pollution condition.

When the cooling module one 2023 is in operation, the heater 101 heats the cooling fluid in the cooling fluid tank 10 to a suitable temperature, for example 37.2 ℃. The temperature in the coolant tank 10 is monitored and detected by the temperature sensor 102, and then the peristaltic pump 20 starts to work to deliver the coolant to the first optical fiber conduit 301 to form a cooling loop. And then enters the waste liquid tank 50 through a water return pipe 40, wherein a flow sensor 501 is added on the water return pipe 40. The flow sensor 501 is used to confirm whether the cooling liquid flows back normally. In addition, the liquid level sensor 103 can detect the liquid level condition of the cooling liquid in the cooling liquid tank 10, and when the cooling liquid is insufficient, an alarm signal is sent to require the replacement or replenishment of the cooling liquid. Preferably, the cooling liquid is preferably cooled by water, so that the cold source is stable, the effect is good, and the preparation cost is low. The cooling liquid tank 10 can be directly adapted to a conventional saline bottle without an additional switching structure, and the saline bottle is only required to be placed in the cooling liquid tank 10 when the cooling liquid is replaced and is connected with a water delivery pipe.

Referring to fig. 7, the structure of the first optical fiber conduit 301 may be roughly: the first optical fiber conduit 301 comprises an optical fiber 1, a cooling inner tube 2 and a cooling outer tube 3. Wherein the optical fiber 1 is positioned in the cooling inner tube 2, and an axial gap between the outer wall of the optical fiber 1 and the inner wall of the cooling inner tube 2 forms a first circulation channel. The cooling inner pipe 2 is arranged in the cooling outer pipe 3, and a second circulation channel is formed by an axial gap between the inner wall of the cooling outer pipe 3 and the outer wall of the cooling inner pipe 2. The near end of the first circulation channel and the near end of the second circulation channel are communicated with the near end of the cooling outer tube 3 to form a return cavity 6; the distal end of the first circulation path is communicated with the water inlet pipe 30, and the distal end of the second circulation path is communicated with the water return pipe 40.

Referring to fig. 7 again, the first optical fiber conduit 301 further includes a fastening component 7, the fastening component 7 is used for fastening and connecting the optical fiber 1, the inner tube 2 and the outer tube 3, and the fastening component 7 has a cold liquid inlet 4 communicated with the first circulation channel and a cold liquid outlet 5 communicated with the second circulation channel. The cold liquid inlet 4 is communicated with the water inlet pipe 30, and the cold liquid outlet 5 is communicated with the water return pipe 40.

The optical fiber conduit and the fastening assembly are prior art, and the specific structural characteristics thereof will not be described in detail again.

In the second embodiment, the control host 201 collects and processes feedback information of each module in the multi-wavelength multi-channel laser system during a surgical procedure, and outputs signals to each module. And simultaneously, all the functional modules are controlled to work together in a coordinated manner. The system can complete real-time temperature detection, ablation condition evaluation, man-machine interaction operation, automatic adjustment of laser power and cooling module efficiency. For example, the control host 201 may regulate and control working parameters such as laser output power, laser output time, light output mode, and flow rate of cooling liquid in real time according to the ablation condition.

Further, the control host 201 monitors the operating parameters of the laser module 202, the optical fiber temperature measurement module 206, and the cooling module in real time; when the operating parameter exceeds a safe operating threshold, the control host 201 will cause the laser module 202 and/or the cooling module to cease operation.

Example three: and (5) an optimization scheme II related to system temperature control design.

Referring to fig. 4, compared to the second embodiment, the third embodiment is different only in that the first optical fiber conduit 301 and the second optical fiber conduit 302 share one cooling module, and the sharing form or manner can be obtained by those skilled in the art according to the prior art, and is not described again.

Example four: an overall optimized design solution for a multi-wavelength multi-channel system.

Referring to fig. 3 again, the fourth embodiment is an optimization based on the first embodiment, the second embodiment or the third embodiment, and therefore only the difference improvement will be described in detail herein.

Laser ablation unit 200 mainly contain: the system comprises a control host 201, a human-computer interaction module 203, a laser module 202, a cooling module, a power supply module 204, an optical fiber temperature measurement module 206 and an effect evaluation module 207.

(1) The control host 201 is used for receiving the signal and outputting a control signal, and monitoring the ablation process in real time. Therefore, the functions and actions of the control host 201 are mainly embodied in two stages, namely preoperative and postoperative.

A preoperative stage: in cooperation with preoperative software, the control host 201 completes profiling, multi-modal 3D modeling, marking of lesion and neurovascular positions, planning of an appropriate surgical path, and generation of a surgical plan of a patient according to medical image information of the patient. The surgical plan includes fiber optic catheter insertion path planning, pre-ablation zone conditions, laser power used, light extraction time, light extraction pattern, number of ablation channels required, and the like.

In the intraoperative stage: the control host 201 can process the digital image information transmitted by the MRI control center 102 in time, generate a real-time temperature image of a lesion area through an MRI temperature imaging technology and a multi-modal fusion technology, and display the real-time temperature image on the human-computer interaction module 203. In operation, the control host 201 may monitor ablation conditions of a lesion area in real time according to an operation scheme and the real-time temperature image, and synchronously or asynchronously regulate and control laser output powers, laser output times, light emitting modes, and the like of the first laser device 2021 and the second laser device 2022 according to ablation data displayed by the human-computer interaction module 203.

(2) The human-computer interaction module 203 is connected with the control host 201 and is used for receiving input of laser ablation working parameters and displaying real-time information. Referring to fig. 5, the human-computer interaction module 203 is used with the control host, and is displayed in cooperation with a plurality of touch screens, physical keys and working indicator lights. Meanwhile, a plurality of input modes such as a touch screen, a mouse, a keyboard, an entity knob and the like are provided. Therefore, when one part fails, the other part can be used for controlling, and the stability and the safety of the multi-wavelength multi-channel laser system are improved. Specifically, the human-computer interaction module 203 includes a first touch screen 2031, a second touch screen 2032, a third touch screen 2033, an emergency stop switch 2034, a foot pedal controller 2035, a physical button 2036, and an indicator light 2037. The first touch screen 2031 and the second touch screen 2032 are both connected with an industrial personal computer 2012 of the control host 201, and the third touch screen 2033 is connected with a mainboard 2013 of the control host 201.

Further, the first touch screen 2031 comprises an MRI real-time temperature monitoring interface and an ablation area evaluation interface; the second touch screen 2032 comprises a first laser device parameter interface, a second laser device parameter interface and a cooling module parameter interface; and the interface display contents of the third touch screen and the second touch screen are the same or different. Because the stability and the safety of the main board 2013 are higher than those of the industrial personal computer 2012, when the second touch screen 2032 has a fault, the ablation operation can be continued according to the display content of the third touch screen 2033.

Further, the emergency stop switch 2034 can emergency shut down the laser module, the fiber optic conduit, the cooling module, etc., but not the human interaction module 203. The foot pedal controller 2035 controls switching between laser emission and laser light of different wavelengths of the laser module 202 and switching of light emission modes. The control host 201 monitors the operating parameters of the laser module 202, the optical fiber temperature measuring module 206 and the cooling module in real time; when the operating parameter exceeds a safe operating threshold, the control host 201 will cause an emergency stop of the laser module 202 and/or the cooling module.

(3) The laser module 202 may emit multiple lasers of the same or different energies. In this embodiment, the laser module 202 includes a first laser device 2021 and a second laser device 2022. The first laser device 2021 can generate laser with a first wavelength, and the second laser device 2022 can generate laser with a second wavelength. The first wavelength and the second wavelength may be the same or different. Preferably, in the present invention, the first laser device 2021 is configured to generate laser light having a first wavelength of 980nm, and the second laser device 2022 is configured to generate laser light having a second wavelength of 1064nm. In an ablation operation, the control host 201 controls the first laser device 2021 and the second laser device 2022 to emit laser simultaneously or controls only one of the first laser device 2021 and the second laser device 2022 to emit laser; the regulation and control instructions for enabling the first laser device 2021 and the second laser device 2022 to emit light according to a certain specific sequence can be made according to the operation requirement. The regulation and control instruction can be laser light-emitting power, light-emitting time, a light-emitting mode, synchronous light-emitting, asynchronous light-emitting, light-emitting angle and the like.

Further, a semiconductor laser is used at a wavelength of 980nm, and a semiconductor laser or a Nd: YAG laser is used at a wavelength of 1064nm. The laser with the wavelength of 980nm and the laser with the wavelength of 1064nm are high-power lasers commonly used for ablation. Laser light of 1064nm wavelength has a stronger penetration than laser light of 980nm wavelength, and thus a larger ablation volume can be achieved. Therefore, it can be seen that multi-wavelength multichannel laser system, its laser that both can produce a plurality of wave bands, the laser of different wave bands can cooperate rather than the fiber conduit of corresponding connection to realize that the multichannel light-emitting melts again, and then can realize melting to the accurate form fit of regular or irregular tumour. Use multi-wavelength multichannel laser system can need not consider the diameter size or the shape characteristic of tumour, really realize no matter size, shape, position, compare with prior art the utility model discloses to improve LITT's application disease scope greatly, melt the scheme more nimble, be worth promoting in the field.

Of course, the laser module 202 may also be configured to have only one laser device, but the laser device is configured to emit laser light at multiple wavelengths, each wavelength being matched to a corresponding fiber optic catheter, thereby achieving multi-wavelength light extraction and multi-channel ablation. Further alternatively, the laser module 202 is configured to have at least two laser devices, and the two laser devices can emit laser light with the same wavelength band, and the implementation of these improvements can be implemented according to the prior art, which will not be described herein.

(4) The cooling module cools the optical fiber conduit unit 300 and the tissue around the optical fiber conduit unit 300 by driving and controlling the circulation flow of the cooling medium. Please refer to the second embodiment of the present invention in the detailed description of the cooling module.

(5) The power module 204 provides stable power support for each of the other modules. Referring to fig. 9, a schematic diagram of power distribution of a power module in a laser ablation unit is shown. The power module 204 provides power for each module in the laser ablation unit 200, for example, the control host 201, the human-computer interaction module 203, the laser module 202, the optical fiber temperature measurement module 206, the effect evaluation module 207, and the like. The power module 204 mainly includes at least one UPS device and at least one power distribution control board. Wherein, the electric energy input end of the laser ablation unit 200 is connected with a power line. One end of the power line is connected with a commercial power end, the other end of the power line is connected with the UPS equipment, namely, the output end of the power line is connected with the electric energy input end of the UPS equipment. The UPS equipment is in a charging state when the commercial power end normally supplies power, and once the commercial power end or the power line breaks down or is interrupted, the UPS equipment immediately outputs stored electric energy to the laser ablation unit 200, so that the power supply continuity and normal use of each module of the laser ablation unit 200 are ensured. Preferably, the sustainable power supply time of the UPS device is about 15 min.

In addition, the circuit connecting wires of the modules in the laser ablation unit 200 are all arranged on the power distribution control board in a centralized manner. This has the advantages of reasonable distribution of circuit management of the modules in the laser ablation unit 200, clear and definite wiring, easy maintenance, and contribution to further reducing the occupied space of the laser ablation unit 200. Furthermore, the power distribution control board is provided with a plurality of connecting terminals, a built-in independent switch power supply and a latching relay. Connecting terminal difference electric connection has 5 at least electric energy output channel, electric energy output channel contains SP1 passageway, SP2 passageway, SP3 passageway, SP4 passageway and SP5 passageway. The SP1 channel, the SP2 channel, the SP3 channel, the SP4 channel, and the SP5 channel may be electrically connected to each module of the laser ablation unit 200, respectively. For example, the SP1 channel is electrically connected to the UPS device, and is used as a total input of the whole board power source, the SP2 channel is connected to the first touch screen 2031, the SP3 channel is connected to the second touch screen 2032, the SP4 channel is connected to the control host 201, and the SP5 channel is connected to the 4-in-1 switching power source.

More preferably, the 4-in-1 switching Power supply has at least 4 paths of electric energy output channels, and the 4 paths of electric energy output channels comprise a Power-1 channel, a Power-2 channel, a Power-3 channel and a Power-4 channel. The 4 electric energy output channels can output the same or different direct current Power supplies, and the Power-1 channel, the Power-2 channel, the Power-3 channel and the Power-4 channel operate independently of one another, do not interfere with one another, and guarantee the Power utilization safety.

In a preferred embodiment of the present invention, the built-in independent switching power supply is electrically connected to the latching relay. Preferably, the latching relay is electrically connected to the SP5 channel. Meanwhile, the latching relay is connected to a PCS-1 channel, and the PCS-1 channel is used for electrically connecting to the emergency stop control switch 2034 and the key switch 205. The power distribution control board also includes a PCS-2 channel connected to the cooling module. The advantage of wiring like this lies in, can realize weak current control forceful electric power, under the prerequisite of guaranteeing equipment functional reliability, has improved equipment power consumption security, just latching relay can also keep the last operating condition of equipment, and like this when equipment from scram to resume normal operating condition need the re-operation to open the button, avoids bringing the electrical safety problem because of scram mistake resumes.

(6) The fiber temperature measuring module 206 is used for collecting and processing the real-time temperature of the optical fiber conduit unit 300 and the tissues around the optical fiber conduit unit 300 transmitted by the temperature measuring optical fiber 8; and the control host 201 is assisted to generate accurate corrected temperature images, so that real-time temperature feedback and more accurate ablation operation can be realized in the operation. Please refer to the first embodiment of the present invention.

(7) An effectiveness evaluation module 207. The effect evaluation module 207 performs real-time estimation on the ablation condition of the tissue by using an arrhenius model or a CEM43 model in the operation; the control host 201 generates a regulation instruction of at least one of the following in real time according to the ablation progress fed back by the effect evaluation module 207: laser output power, light emitting time, light emitting mode and cooling flow rate.

Furthermore, the multi-wavelength multi-channel laser system further comprises other peripheral interfaces, such as a USB interface, a safety switch interface, a network cable, an optical drive and the like, so as to ensure normal operation of the system.

Further, the multi-wavelength multi-channel laser system further comprises software, wherein the software performs at least one of the following functions.

(1) Generating a surgical plan, wherein the surgical plan contains information corresponding to each of the N laser devices, wherein the information includes at least one of: planning an ablation area and/or an ablation volume, laser power used for achieving a preset ablation result, light emitting time, a light emitting mode, the number of required ablation channels and a cooling flow rate;

(2) controlling in real time, under the guidance of the magnetic resonance guidance unit 100, according to each of the N laser devices, respectively according to the corresponding surgical plan and the corrected temperature image, adjusting and controlling working parameters of each laser device and the cooling module in a working state in real time, and performing ablation monitoring in real time;

(3) comparing and analyzing the information in the surgical plan corresponding to each laser device and the information of the laser device after surgery, wherein the analysis can adopt Boolean operation, and ablation result information is generated according to the comparison result and is displayed on the man-machine interaction module 203; wherein, the content of comparison includes the following: a planned ablation area and/or a planned ablation volume, and a post-operative actual ablation area and/or an actual ablation volume; the ablation result information at least comprises one of the following information: ablation area percentage, ablation volume percentage, ablation area percentage, and pre-and post-ablation contrast maps.

The above-mentioned only be the embodiment of the present invention, not consequently the restriction of the patent scope of the present invention, all utilize the equivalent structure or equivalent flow transform made of the content of the specification and the attached drawings, or directly or indirectly use in other relevant technical fields, all including in the same way the patent protection scope of the present invention.

Claims (16)

1. A multi-wavelength multi-channel laser system for neurosurgical thermal ablation, the multi-wavelength multi-channel laser system comprising:

magnetic resonance guidance unit (100): it comprises an MRI device (101) and an MRI control center (102); the MRI control center (102) is configured to perform at least one of the following: data acquisition, data processing, image reconstruction, image display and image storage;

laser ablation unit (200): which is connected with the magnetic resonance guiding unit (100), the laser ablation unit (200) comprises a control host (201); the control host (201) completes at least one of the following according to the digital image information of the patient: profiling, 3D modeling, generating a surgical plan of the patient; the control host (201) fuses the digital image information through an MRI temperature imaging technology to generate a real-time temperature image, and displays the real-time temperature image on a human-computer interaction module (203);

the laser ablation unit (200) further comprises a laser module (202) connected with the control host (201), wherein the laser module (202) is provided with N laser devices, and N is more than or equal to 2; the control host (201) synchronously or asynchronously regulates and controls partial or all laser working parameters in the N laser devices according to the operation scheme and the real-time temperature image; and the number of the first and second groups,

fiber conduit unit (300): which is connected with the laser ablation unit (200), the fiber-optic catheter unit (300) is provided with M fiber-optic catheters for ablation.

2. The multi-wavelength multi-channel laser system for neurosurgical thermal ablation according to claim 1, wherein M is greater than or equal to 1.

3. The multiwavelength multichannel laser system for neurosurgical thermal ablation as claimed in claim 1, wherein when N is greater than or equal to 2 and M is equal to N, each of the fibre optic conduits is connected with each of the laser devices in a one-to-one correspondence, forming N ablation channels; and/or the presence of a gas in the gas,

the laser module (202) is provided with N laser devices, and N is at least 2; the optical fiber conduit unit (300) is provided with M optical fiber conduits, wherein M is at least 1; the N laser devices are respectively connected with each optical fiber conduit; and/or the presence of a gas in the gas,

the laser module (202) is provided with N laser devices, and N is at least 1; the optical fiber conduit unit (300) is provided with M optical fiber conduits, M is at least 2; m fiber optic conduits are respectively connected with each laser device.

4. The multi-wavelength, multi-channel laser system for neurosurgical thermal ablation of claim 1 or 3, wherein each of the laser devices emits laser light of at least one wavelength; and/or the N laser devices all emit laser with the same wavelength; and/or one part of the N laser devices emits laser with a first wavelength, and the other part of the N laser devices emits laser with a second wavelength, wherein the second wavelength is different from the first wavelength.

5. The multi-wavelength multi-channel laser system for neurosurgical thermal ablation according to claim 1, wherein when N equals 2, the laser module (202) comprises a first laser device (2021) and a second laser device (2022); the control host (201) synchronously or asynchronously regulates and controls the laser working parameters of the first laser device (2021) and the second laser device (2022) according to the surgical scheme and the real-time temperature image;

meanwhile, the optical fiber conduit unit (300) comprises a first optical fiber conduit (301) and a second optical fiber conduit (302); the first optical fiber conduit (301) is connected with the first laser device (2021), and the second optical fiber conduit (302) is connected with the second laser device (2022).

6. The multi-wavelength multi-channel laser system for neurosurgical thermal ablation according to claim 5, wherein at least one of the first optical fiber conduit (301) and the second optical fiber conduit (302) is provided with a temperature measuring optical fiber (8), and the temperature measuring optical fiber (8) is used for detecting real-time temperature of the optical fiber conduit unit (300) and tissues around the optical fiber conduit unit (300); the temperature measuring optical fiber (8) is connected with an optical fiber temperature measuring module (206) in the laser ablation unit (200); the optical fiber temperature measurement module (206) is connected with a temperature correction module (2011) in the control host (201), and the temperature correction module (2011) is used for correcting the temperature.

7. The multi-wavelength multi-channel laser system for neurosurgical thermal ablation according to claim 5, wherein the first laser device (2021) generates laser light having a first wavelength, and the second laser device (2022) generates laser light having a second wavelength; the first wavelength and the second wavelength are the same or different; the laser module (202) has a first laser device (2021) that generates laser light at the first wavelength and a second laser device (2022) that generates laser light at the second wavelength.

8. The multi-wavelength multi-channel laser system for neurosurgical thermal ablation according to claim 7, wherein the first wavelength is 980nm and the second wavelength is 1064nm.

9. The multi-wavelength multi-channel laser system for neurosurgical thermal ablation of claim 5, wherein the laser operating parameters comprise at least one of: laser output power, light emitting time of laser and light emitting mode of laser.

10. The multiwavelength multichannel laser system for neurosurgical thermal ablation according to any of claims 7 to 9, wherein the laser module (202) is further configured with a cooling module connected with the control host (201) and the fibre-optic catheter unit (300);

the control host (201) controls the operation of the cooling module, and the cooling module cools the optical fiber conduit unit (300) and the surrounding tissues of the optical fiber conduit unit (300) by driving and controlling the flow of the cooling medium.

11. The multiwavelength, multichannel laser system for neurosurgical thermal ablation as claimed in claim 10, wherein the fiber optic catheter unit (300) has the first (301) and second (302) fiber optic catheters in identical configuration; wherein the first optical fiber conduit (301) comprises an optical fiber, a cooling inner tube and a cooling outer tube; and/or the optical fiber is one of a ring optical fiber, a dispersion optical fiber and a side-emitting optical fiber; and/or the proximal end of the optical fiber is one of a beveled end, a semi-circular end, a spherical end, a conical end, and a chisel end.

12. The multiwavelength multichannel laser system for neurosurgical thermal ablation according to claim 10, wherein the laser ablation unit (200) comprises a control host (201), a human-machine interaction module (203), a laser module (202), a cooling module, a power supply module (204), a fiber thermometry module (206) and an effect evaluation module (207).

13. The multiwavelength multichannel laser system for neurosurgical thermal ablation according to claim 12, wherein the power module (204) has at least one UPS device and at least one power distribution control board; wherein the electric energy input end of the laser ablation unit (200) is connected with a power line; one end of the power line is connected with a commercial power end, and the other end of the power line is connected with the electric energy input end of the UPS equipment.

14. The multiwavelength multichannel laser system for neurosurgical thermal ablation as claimed in claim 13, wherein the power distribution control board comprises a number of connection terminals, a built-in separate switching power supply and latching relays; the latching relay is electrically connected with a PCS-1 channel, and the PCS-1 channel is used for being electrically connected with an emergency stop switch (2034) and a key switch (205); the power distribution control board also includes a PCS-2 channel connected to the cooling module.

15. The multiwavelength multichannel laser system for neurosurgical thermal ablation according to claim 12, wherein the human-machine interaction module (203) comprises a touch screen one (2031), a touch screen two (2032), a touch screen three (2033), an emergency stop switch (2034), a foot pedal controller (2035), physical buttons (2036), and indicator lights (2037).

16. The multiwavelength multichannel laser system for neurosurgical thermal ablation according to claim 15, wherein the first (2031) and second (2032) touch screens are connected to an industrial personal computer (2012) of the control host, and the third (2033) touch screen is connected to a motherboard (2013) of the control host;

the first touch screen (2031) comprises an MRI real-time temperature monitoring interface and an ablation area evaluation interface; the second touch screen (2032) comprises a first laser device parameter interface, a second laser device parameter interface and a cooling module parameter interface; the interface contents displayed by the third touch screen and the second touch screen are the same or different.

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