CN217543121U - Sample collecting bottle with cover body - Google Patents

Abstract

The utility model provides a sample collecting bottle with a cover body, which comprises a bottle body with an opening at one end, wherein a fragile ampoule is arranged in the bottle body, and a cracking liquid is filled in the fragile ampoule; the sample collecting bottle also comprises a cover body which is used for covering and sealing the opening of the bottle body, the cover body comprises a dripper and a collecting rod, the dripper is provided with a dripper nozzle, a blocking platform and a connecting part from top to bottom, a dripper cavity from small to large is formed in the dripper nozzle, the blocking platform and the connecting part, and the collecting rod penetrates through the dripper cavity through a handle to be connected with the dripper; the cover body is detachably connected with the bottle body. In biological sample inspection procedure, sample collection bottle and the lid cooperation that contains the sampling stick can fully collect the sample in the sampling stick to accomplish the pretreatment step of the schizolysis of sample in step, improve the utilization ratio of sampling sample. The utility model discloses can be used to the detection of new crown pneumonia.

Description

Sample collecting bottle with cover body

Technical Field

The utility model belongs to the technical field of medical instrument, especially, relate to a sample collecting bottle that has a lid of collecting liquid sample.

Background

There are a variety of clinical Lateral Flow immunoassay devices (Lateral Flow) that can be used to detect the presence of analytes in a sample, such as hormones, sugars, adulterants, drugs of abuse, new corona viruses, and the like. Typically, after a fluid sample is collected and added to a lateral flow immunoassay device, the amount of analyte in the fluid sample is measured.

Wherein the fluid sample may be any volume of fluid that is tested, examined, or studied. The fluid sample may be derived from any fluid, for example a bodily fluid such as saliva or blood or urine or other fluid to be tested such as a water sample from a source of contamination, a fluid sample from a beverage, etc.

Liquid samples are typically collected and absorbed using a sampling wand having a collection element formed of an absorbent material such as a pad or sponge attached to one end of a handle. The collection element allows a sufficient volume of sample fluid to be absorbed from the fluid source, the presence of sample fluid in the collection element causing the interior of the collection element to expand. The collection element will normally hold the sample, until the collection member is manipulated to release the sample. During detection, a fluid sample needs to be extruded out of a collecting element of a sampling rod and then added to a lateral flow immunoassay device; in some assays, the fluid sample may be mixed with the buffer solution prior to processing, or the fluid sample may be squeezed off the collection element of the sample wand and added to the buffer solution.

Taking the detection of the new coronavirus as an example to illustrate the existing operation, a collection bottle with a physiological degradation solution of the new coronavirus prestored inside is used for collecting a fluid sample on a collection element, namely, a collection element end of a sampling rod is inserted into the collection bottle, and the collection element is contacted with the side wall or the bottom of a collection bottle body to be extruded so that the fluid sample flows out of the collection bottle for sample collection. The prior art has the problems that the fluid sample on the collecting element cannot be released sufficiently (more fluid sample remains on the collecting element and cannot be used for detection), or when buffer solution exists in the collecting bottle, the collecting element absorbs and takes away part of the buffer solution or the mixed solution of the buffer solution and the fluid sample, so that the subsequent detection liquid amount is insufficient, and the detection result is inaccurate (for example, false negative) or even the detection fails due to the insufficient sample. And, the collected fluid sample is transferred to a dripper and then added to a detection device, which can cause contamination to the operator.

SUMMERY OF THE UTILITY MODEL

An object of the utility model is to provide a sample receiving flask with lid for collecting liquid sample to exist not enough among the prior art. The sample collecting bottle can fully collect and squeeze samples, release the lysate when in use, and facilitate product packaging and operation.

For this purpose, the method comprises the following steps, the above object of the present invention is achieved by the following technical solutions:

a sample collecting bottle with a cover body comprises a bottle body with an opening at one end, wherein a fragile ampoule is arranged in the bottle body, and a cracking solution is filled in the fragile ampoule; the sample collecting bottle also comprises a cover body which is used for covering and sealing the opening of the bottle body, the cover body comprises a dripper and a collecting rod, the dripper is provided with a dripper nozzle, a blocking platform and a connecting part from top to bottom, a dripper cavity from small to large is formed in the dripper nozzle, the blocking platform and the connecting part, and the collecting rod penetrates through the dripper cavity through a handle to be connected with the dripper; the cover body is detachably connected with the bottle body.

When adopting above-mentioned technical scheme, the utility model discloses can also adopt or make up and adopt following technical scheme:

as the utility model discloses a preferred technical scheme: after the cover body covers the bottle body, the blocking platform of the cover body is positioned on the platform.

As the utility model discloses a preferred technical scheme: after the collection rod is inserted into the dripper for matching, the collection element of the collection rod is positioned at the connecting part, and the handle of the collection rod is in interference fit with the minimum position of the dripper cavity.

As the utility model discloses an preferred technical scheme: an annular groove is arranged on the inner side wall of the bottle body close to the bottle mouth; the outer side wall of the connecting part is provided with an annular bulge matched with the annular groove of the bottle body; after the cover body covers the bottle body, the connecting part is positioned in the bottle body, and the annular bulge is positioned in the annular groove in the bottle body.

As the utility model discloses a preferred technical scheme: more than one recess is circumferentially arranged on the inner side wall of the bottle body close to the bottle mouth, and more than one salient point matched with the recess is circumferentially arranged on the outer side wall of the connecting part; after the cover body covers the bottle body, the connecting parts are positioned in the bottle body, and the salient points are in one-to-one correspondence with the depressions of the bottle body.

As the utility model discloses a preferred technical scheme: the handle of the collecting rod is of a bending structure.

As the utility model discloses a preferred technical scheme: the middle part of the collecting rod handle is provided with a baffle. When the collecting rod is inserted and matched with the dripper, the baffle is positioned outside the dripper.

As the utility model discloses a preferred technical scheme: the baffle is arc.

As the utility model discloses a preferred technical scheme: the bottle body is internally provided with a fragile ampoule which is internally provided with cracking liquid.

As the utility model discloses a preferred technical scheme: an isolation net is arranged in the bottle body.

As the utility model discloses an preferred technical scheme: the bottle body and the water dropper of the collecting bottle are both made of soft plastic.

Advantageous effects

The utility model discloses a sample collecting bottle is equipped with and gathers excellent and dripper and insert the cooperation and form integrative lid, when collecting the sample, fully extrudees the collecting element who gathers the excellent through dripper drip mouth department, has reduced the volume of remaining of fluid sample on collecting element, has increased the fluid sample volume of release, then can add the sample to detection device through the dripper after invering the collecting bottle on. And, just release the lysate when using, can make the lid close pack on collecting the bottle and pack, make things convenient for product packaging and operation. In biological sample inspection procedure, sample collecting bottle and the lid cooperation that contains the sampling stick, can fully release and collect the sample in the sampling stick to accomplish the pretreatment step of the schizolysis of sample in step, improve the utilization ratio of sampling sample, improved the accuracy that detects and reduced the failure rate that detects.

Drawings

Fig. 1 is a schematic view of a sample collection bottle with a cover according to the present invention.

Fig. 2 isbase:Sub>A schematic sectional view taken along linebase:Sub>A-base:Sub>A in fig. 1.

Fig. 3 is a schematic view of the bottle of fig. 2.

Fig. 4 is a schematic view of the cover in fig. 2.

Fig. 5 is a schematic view of a sample collection bottle with a cover body having another structure according to the present invention.

FIG. 6 is a schematic cross-sectional view of the specimen collection vial of FIG. 5 with a cap.

Fig. 7 is a schematic cross-sectional view of a sample collection bottle with a cap according to another embodiment of the present invention.

Fig. 8 is a schematic cross-sectional view of a sample collection bottle with a cap having another structure according to the present invention.

Fig. 9 is a schematic cross-sectional view of the sample collection procedure of the sample collection bottle with cap according to the present invention (the drip nozzle begins to squeeze the collection member).

Fig. 10 is a cross-sectional schematic view of the sample collection vial with the cap of fig. 1 during sample collection (the drip nozzle continues to squeeze the collection member).

FIG. 11 is a schematic cross-sectional view of the sample collection vial with cap of FIG. 1 during sample collection (with the collection wand pulled from the dripper).

FIG. 12 is a schematic view of the sample collection vial with cap of FIG. 1 after collection of the sample and subsequent addition of the sample to the test device.

Fig. 13 is a schematic cross-sectional view of a sample collection bottle with a cap having another structure according to the present invention.

FIG. 14 is a schematic view of the bottle of FIG. 13.

Fig. 15 is a cross-sectional view of another configuration of the specimen collection bottle with cap of fig. 13 during specimen collection (the frangibility ampoule is crushed).

Fig. 16 is a schematic cross-sectional view of a sample collection vial having a cap with another configuration according to the present invention.

Fig. 17 is a schematic view of another sample collection bottle with a cap according to the structure of fig. 13, after collecting a sample, the sample is added to a detection device.

FIG. 18 is a schematic view of another configuration of the sample collection vial with cap of FIG. 16 after collection of a sample and subsequent addition of the sample to the test device.

Reference numerals

Bottle 100, opening 101, platform 102, sealing membrane 103, breakable ampoule 104, breakable ampoule 105, isolation mesh 106, annular groove or recess 104, cover 200, collection rod 210, handle 211, collection component 212, baffle 213 on the handle, dripper 220, dripper 221, baffle 222, connecting portion 223, annular protrusion or bump 224, dripper opening 225, lysate 300, sample 400, mixed solution 500, detection device 600

Detailed Description

The invention will be described in further detail with reference to the accompanying drawings and specific embodiments.

The above detailed description is provided for explaining the present invention, and is only a preferred embodiment of the present invention, but not for limiting the present invention, and any modifications, equivalent replacements, improvements, etc. made by the present invention are within the scope of the present invention.

As shown in fig. 1-4, the present invention provides a sample collection bottle with a cover, which has a bottle body 100, an opening 101 is provided at one end of the bottle body, a platform 102 is provided at the opening, a lysate 300 is provided in the bottle body 100 at an initial state, the opening of the bottle body is sealed by a sealing film 103, and thus the lysate is sealed in the bottle body. The sample collection bottle further comprises a cap 200, and in an initial state, the cap may not be covered on the bottle body, that is, the bottle body and the cap are separately placed and separately packaged. When the lid closes on the bottle, its lid closes the opening of sealed bottle, also sealed bottle promptly.

As shown in fig. 4, the cap body 200 includes a dripper 220 and a collecting rod 210. The dripper 220 is of an integrated structure consisting of a dripper 221, a baffle table 222 and a connecting part 223, the dripper, the baffle table and the connecting part are arranged from top to bottom, the dripper, the baffle table and the connecting part are hollow, and a dripper cavity from small to large is formed in the hollow part. Specifically, the inside infundibulate cavity that is big end down that is of dripping the mouth, the cavity that keeps off the platform is connected in the cavity bottom of dripping the mouth, also is big end down's infundibulate, and the cavity of connecting portion is the cylindrical structure, and its top is connected in keeping off platform cavity bottom. The drip nozzle cavity, the baffle platform cavity and the connecting part cavity form a large drip head cavity. The cavity of the dripper is in a horn shape, and the cavity is gradually reduced from the bottom to the top. The sampling rod is inserted into the cavity of the dropper, specifically, the collecting rod 210 comprises a handle 211 and a collecting element 212 connected to the tail end of the handle, and the handle of the collecting rod is inserted into the cavity of the dropper from the bottom of the cavity of the dropper, penetrates through the cavity of the dropper, and then protrudes out of the dropper, so that the collecting rod is detachably connected with the dropper. In some embodiments, the handle 211 of the collection rod is in an interference fit with the drip nozzle opening 225, which enables the collection rod to be fixed to the drip emitter and also enables the drip emitter to be sealed.

The utility model discloses in, when the lid closed the bottle, the fender platform 222 of lid was located platform 102, made lid and bottle lid close.

As shown in fig. 2, 3 and 4, an annular groove 104 is formed on the inner side wall of the bottle body near the bottle mouth; meanwhile, the outer side wall of the connecting part of the dripper is provided with an annular bulge 224 matched with the annular groove of the bottle body. When the cover body is closed with the bottle body, the dripper is inserted into the opening of the bottle body together with the sampling rod, the baffle platform of the dripper is contacted with the platform of the bottle body, at the moment, the connecting part 223 is positioned in the bottle body 100, and the annular bulge is buckled in the annular groove in the bottle body, so that the dripper is fixed with the bottle body, namely the cover body is fixed with the bottle body. In some embodiments, in order to make the cover body and the bottle body form a better seal, the outer diameter of the connecting part is the same as the inner diameter of the opening of the bottle body, and the connecting part and the opening of the bottle body are in zero-clearance insertion fit.

As also shown in fig. 2, 3 and 4, the annular groove formed in the inner sidewall of the bottle body near the bottle mouth may be modified to have more than one recess 104 circumferentially formed in the inner sidewall of the bottle body near the bottle mouth, and to be matched with the recess, and more than one protrusion 224 circumferentially formed on the outer sidewall of the connecting portion, and the protrusion of the connecting portion is located in the recess of the bottle body to realize the matching and fixing of the dropper and the bottle body. In some embodiments, the depressions and the protrusions are in one-to-one correspondence, and the depressions and the protrusions are 3-10 in number and are uniformly distributed on the inner side wall of the bottle body in the circumferential direction and the outer side wall of the connecting portion in the circumferential direction.

In some embodiments, as shown in fig. 5 and 6, to better ensure that the collection rod 210 does not become detached from the drippers 220 before use, the collection rod handle is provided with a bent structure 211.

In some embodiments, as shown in fig. 8, the middle of the collection rod handle 211 is provided with a baffle 213. When the collecting rod is inserted and matched with the dripper, the baffle is positioned outside the dripper. In this way, it is avoided that the operator, when squeezing the collecting element, may be contaminated by liquid brought out of the drip nozzle. In some preferred embodiments, the baffle 213 is arcuate, as shown in FIG. 7.

In other embodiments, the collection bottle body and cap body are constructed as in the embodiment of FIGS. 1-8. However, the lysis solution is not directly contained in the bottle body, but a fragile ampoule 104 containing the lysis solution 300 is provided in the bottle body, as shown in FIGS. 13 to 18. Thus, the opening of the bottle body does not need to be sealed in advance in the state of the lysate, a sealing film is not arranged, and the bottle body 100 and the cover body 200 can be covered together for packaging in the initial state (when not used), so that the packaging is saved and the use by an operator is facilitated. When sample collection is required, as shown in fig. 13, the cap body 200 is detached from the bottle body 100, specifically, the dropper is held by hand and pulled upward relative to the bottle body, the annular protrusion or projection on the outer portion of the dropper is disengaged from the annular groove or recess on the inner portion of the bottle body, the dropper is separated from the bottle body, as shown in fig. 14, and then the frangible ampoule is broken to perform subsequent sample collection, as shown in fig. 15 and 17. In some preferred embodiments, to prevent fragments 105 of the frangible ampoule from falling out of the dripper or blocking the drip nozzle, an isolation mesh 106 is provided in the bottle body, and the frangible ampoule 104 is positioned between the isolation mesh 106 and the bottom of the bottle body 100. As shown in fig. 16 and 18, so that the mixing fluid flows out through the drip nozzle 221 without being disturbed by the shards of the frangible ampoule when the bottle body 100 is inverted.

The utility model discloses in, collecting bottle 100 and water dropper all adopt the soft plastics material to make, conveniently extrude liquid and knead one's hair breakable ann doubly bottle 104 to also make things convenient for being connected and separating between water dropper and the bottle.

Take the detection of new coronavirus as an example, the operation process of collecting and cracking the saliva sample by using the sample collecting bottle of the utility model is explained in detail. As shown in fig. 1-12, in use, as shown in fig. 3, the lysis buffer 300 is sealed in the vial by the sealing membrane 103; the operator tears the package of the lid (fig. 4) that has the collection stick open, holds the handle, samples the nasal cavity or the oral cavity of the testee through collecting the component, after the sampling, take off the seal membrane at the bottle opening part, close the lid to the bottle opening part again, insert the dripper in the bottle opening part together with the sampling stick soon, make the platform that keeps off the platform contact of dripper to the bottle, at this moment, connecting portion are located the bottle to, annular protruding buckle is in the annular groove in the bottle, thereby the dripper is fixed with the bottle, and the lid is fixed with the bottle promptly, as shown in fig. 2. The handle is held by hand, the collecting rod is slowly pulled out from the dripper and the bottle body by vertical force, and in the process, the collecting element moves towards the dripper in the cavity of the dripper and is gradually pressed by the dripper, as shown in fig. 9. The squeezed collection element then extends out of the dripper at the opening of the nozzle, and the fluid sample 400 on the collection element is squeezed down into the bottle and mixes with the lysate in the bottle, as shown in fig. 10. Until the entire collecting member of the collecting rod is completely squeezed out of the drip nozzle, as shown in fig. 11. The saliva sample flowing into the sample collection bottle is mixed with the lysate prestored in the sample collection bottle, the sample is cracked within the preset time, the bottle body is inverted, the opening of the drip nozzle faces downwards, the bottle body is squeezed, the mixed solution 500 drips out from the opening 225 of the drip nozzle and is added to the neocorona antigen detection device 600, and the neocorona antigen detection is completed. The detection device can adopt lateral cross-flow detection test paper of a double-antibody sandwich method.

The utility model discloses another kind of sample collecting bottle (fig. 13-14) carries out the operation in-process of collection and schizolysis to the saliva sample, if the lid is connected under the circumstances when collecting the bottle with the initial condition, extracts the dripper from the bottle earlier, kneads one's hair breakable ann doubly bottle 104, and the lysate in the breakable ann doubly bottle flows out to the bottle, carries out sample collection again, closes the lid to the bottle opening part after gathering, and all the other flows are the same with aforementioned sample collecting bottle operation flow.

In biological sample inspection procedure, sample collecting bottle and sampling rod cooperation can fully collect the sample in the sampling rod, and can accomplish pretreatment steps such as the schizolysis of sample in step. The sampling rod can be used for improving the utilization rate of the sampling specimen in the detection items of allergens, tumor markers, gonadal markers, alpha-functional markers, infectious disease markers, diabetes markers, hepatic fibrosis markers and the like which need to be sampled by the sampling rod in the detection of the new coronavirus.

Claims (7)

1. A sample collecting bottle with a cover body comprises a bottle body with an opening at one end, and is characterized in that a fragile ampoule is arranged in the bottle body, and cracking liquid is filled in the fragile ampoule; the sample collecting bottle also comprises a cover body which is used for covering and sealing the opening of the bottle body, the cover body comprises a dripper and a collecting rod, the dripper is provided with a dripper nozzle, a baffle table and a connecting part from top to bottom, a dripper cavity from small to large is formed inside the dripper nozzle, the baffle table and the connecting part, and the collecting rod penetrates through the dripper cavity through a handle to be connected with the dripper; the cover body is detachably connected with the bottle body.

2. The specimen collection bottle with cap of claim 1, wherein the interior sidewall of the body has an annular groove proximate the mouth; the outer side wall of the connecting part is provided with an annular bulge matched with the annular groove of the bottle body; after the cover body covers the bottle body, the connecting part is positioned in the bottle body, and the annular bulge is positioned in the annular groove in the bottle body.

3. The specimen collection bottle with a cap according to claim 1, wherein the inner sidewall of the bottle body near the bottle mouth is circumferentially provided with more than one recess, and the outer sidewall of the connecting portion is circumferentially provided with more than one convex point matching with the recess; after the cover body covers the bottle body, the connecting parts are positioned in the bottle body, and the salient points are in one-to-one correspondence with the depressions of the bottle body.

4. The specimen collection bottle with cap of claim 1, wherein the collection wand handle is of a bent configuration.

5. The specimen collection bottle with cap of any of claims 1-3, wherein the central portion of the collection wand handle is provided with a baffle.

6. The specimen collection bottle with cap of claim 5, wherein the baffle is arcuate.

7. The specimen collection bottle with cap of claim 1, wherein a barrier mesh is provided within the bottle body.

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