CN217459440U

CN217459440U - Low-temperature light radiation box for cell culture

Info

Publication number: CN217459440U
Application number: CN202220246795.4U
Authority: CN
Inventors: 倪锋; 闫杰; 何加铭; 杨茗予; 傅松森; 郭丽华; 赵增祥
Original assignee: Ningbo Lida Pilot Biotechnology Co ltd
Current assignee: Ningbo Lida Pilot Biotechnology Co ltd
Priority date: 2022-01-29
Filing date: 2022-01-29
Publication date: 2022-09-20
Anticipated expiration: 2032-01-29

Abstract

The utility model discloses a low temperature ray radiation box for cell culture, it includes a box, the box openly is equipped with the chamber door, the chamber door is opened there is an operation mouth that communicates box inner space, the operation mouth is equipped with a sealing baffle that can open and shut, be equipped with the condenser pipe in the box, be equipped with tray and the first drive arrangement of drive tray court operation mouth reciprocating motion that is used for placing the culture dish in the box, be equipped with the optical radiation generator directly over lieing in the tray in the box. The utility model discloses can realize automatic ultraviolet crosslinking operation, reduce operating personnel burden.

Description

Low-temperature light radiation box for cell culture

Technical Field

The utility model relates to a biological detection technical field specifically is a low temperature light radiation case for cell culture.

Background

In a biological experiment, a visible light radiation device is needed, in order to ensure the stability of a biological sample under light radiation, an operator usually puts the whole photo-crosslinking device into an environment of 4 ℃ to quickly absorb heat released in the photo-crosslinking process so as to keep the biological sample from deteriorating, but the method is troublesome to operate and consumes physical strength of the operator; in addition, the method of putting the whole photocrosslinking equipment into a low-temperature environment (such as a refrigerator) needs to open a refrigerator door, then opens a photocrosslinking instrument door, then puts cells needing irradiation into the photocrosslinking instrument, and finally closes the photocrosslinking instrument door and the refrigerator door, and a photocrosslinking instrument power line can be clamped in the refrigerator door, so that the refrigerator door cannot be completely closed, the operation is troublesome, and potential safety hazards also exist. Therefore, there is a need for a fully automatic low temperature environmental control cabinet that can automate the photo-crosslinking process.

SUMMERY OF THE UTILITY MODEL

The utility model discloses the technical problem that will solve is: the low-temperature light radiation box for cell culture can realize automatic light crosslinking operation and reduce the burden of operators.

The utility model adopts the technical proposal that: the utility model provides a low temperature ray radiation case for cell culture, it includes a box, the box openly is equipped with the chamber door, the chamber door is opened there is the operation mouth of a intercommunication box inner space, the operation mouth is equipped with a sealing baffle that can open and shut, be equipped with the condenser that is used for the internal temperature of cooler bin in the box, be equipped with tray and the first drive arrangement of drive tray towards operation mouth reciprocating motion that are used for placing the culture dish in the box, be equipped with the ray radiation generator directly over lieing in the tray in the box.

After the structure more than adopting, the utility model has the advantages of it is following: be equipped with the condenser in the box, provide the interior low temperature environment of box, open the operation mouth that has one to supply to place the tray discrepancy of culture dish on the chamber door of box, the tray passes through drive arrangement and realizes automatic movement and stretch out to the operation mouth for operating personnel need not to open the chamber door and just can take the tray, and in addition, the operation mouth is equipped with a sealing baffle that can open and shut, has avoided carrying out the heat exchange in the box and outside the box, influences the inside low temperature environment of box.

Preferably, a second driving device for driving the sealing baffle to open and close is arranged on the box door, so that automatic opening and closing of the sealing baffle is realized.

Preferably, the first driving device and the second driving device are linear motors, the tray is arranged on the linear motors and is driven by the linear motors to move, one end of the sealing baffle is connected to the linear motors, and the other end of the sealing baffle is connected to the operation opening in an openable and closable manner.

Preferably, a connecting rod is arranged between the sealing baffle and the linear motor, one end of the connecting rod is fixed on the linear motor, the other end of the connecting rod is hinged to the sealing baffle, and the sealing baffle is hinged to the operation port, so that the sealing baffle can be opened and closed through a simple and stable mechanical transmission structure.

Preferably, a connecting rod is arranged between the sealing baffle and the linear motor, one end of the connecting rod is fixed on the linear motor, the other end of the connecting rod is fixed on the sealing baffle, a sliding groove is formed in the operation opening along the movement direction of the linear motor, and the sealing baffle is provided with a sliding rail in sliding fit with the sliding groove, so that the sealing baffle can be opened and closed through a simple and stable mechanical transmission structure.

Preferably, the light radiation generator is detachably arranged in the box body right above the tray, the radiation uniformity of samples in different batches can be improved, heat generated in the radiation process can be quickly absorbed by equipment, and the samples are prevented from deteriorating.

Preferably, the sealing baffle is made of a heat insulation material or a heat insulation layer is arranged in the sealing baffle, so that heat exchange inside and outside the box body is reduced to the greatest extent.

Drawings

Fig. 1 is an overall axial view of the present invention.

Fig. 2 is a structure diagram of the inside of the box body of the present invention.

Fig. 3 is a structural view of the outer side of the box door of the present invention.

Fig. 4 is a structure view of the inner side of the door of the present invention.

Wherein, 1, a box body; 2. an operation port; 3. sealing the baffle; 4. a condenser; 5. a culture dish; 6. a tray; 7. a first driving device; 8. an optical radiation generator; 9. a second driving device; 10. a connecting rod; 11. and (4) a box door.

Detailed Description

The present invention will be further described with reference to the accompanying drawings and the following detailed description.

In one embodiment, the present invention provides a low temperature light radiation box for cell culture, as shown in fig. 1, it comprises a box body 1, the inside of the box body 1 is hollow, the front surface of the box body 1 is provided with a door 11 that can be opened and closed, the door 11 can be hinged on the box body 1 in an openable and closable manner, or can be fastened on the box body 1 in a buckling manner, the precondition is that the box body 1 is in a sealing state after the door 11 is closed, as shown in fig. 3, the door 11 is provided with an operation port 2 that is communicated with the inner space of the box body 1, the operation port 2 allows a tray 6 with a culture dish 5 to pass through, the operation port 2 is provided with an openable and closable seal baffle 3 for opening or closing the operation port 2, the seal baffle 3 is automatically opened and closed by a second driving device 9, the second driving device 9 uses a linear motor, because the linear motor has the advantages of simple structure, small motion inertia and high thrust accuracy, when tray 6 removes, culture dish 5 on the tray 6 can not take place acutely to rock, consequently, adopt linear motor can avoid culture dish 5 to follow tray 6 can remain stable and inertia at the removal in-process, the mode of opening and shutting of seal baffle 3 does, seal baffle 3 covers to operation mouth 2 and through articulated mode swing joint in operation mouth 2 department, linear motor installs on 11 inner walls of chamber door and is located operation mouth 2 top, as shown in figure 4, be equipped with a vertical form connecting rod 10 between seal baffle 3 and the linear motor, connecting rod 10 is located seal baffle 3 top and central point and puts, connecting rod 10 one end is fixed in linear motor, the other end articulates in seal baffle 3, drive connecting rod 10 along with linear motor and reciprocate, connecting rod 10 pulls seal baffle 3 again and opens and shuts.

As shown in fig. 2, a condenser 4 is disposed in the box 1, the condenser 4 is generally disposed on the inner peripheral wall of the box 1, in this embodiment, the condenser 4 is disposed on the inner peripheral wall of the box 1 opposite to the box door 11, so that the condenser 4 and the box door 11 are as far away as possible, and the temperature of the condenser 4 is prevented from being affected during the opening and closing process of the box door 11, and the condenser 4 may be disposed on the inner wall of the box 1 to improve the condensation effect.

A tray 6 for placing a culture dish 5 is arranged in the box body 1, a first driving device 7 is arranged between the tray 6 and the box body 1, namely one end of the first driving device 7 is installed in the box body 1, the other end of the first driving device 7 is detachably connected with the tray 6, the tray 6 is driven by the first driving device 7 to reciprocate towards the operation opening 2, namely, the tray 6 can automatically stretch out and draw back to the operation opening 2, and it needs to be explained that when the tray 6 is driven by the first driving device 7 to move out of the operation opening 2, the tray 6 only needs to stretch out to the operation opening 2 by a small section, and then the tray 6 is manually grabbed and the tray 6 is moved out of the operation opening 2; when the tray 6 is to be placed in the box body 1, the tray 6 is slowly pushed to the operation opening 2 manually, after most of the tray 6 is pushed into the box body 1, the tray 6 is driven by the first driving device 7 to completely enter the box body 1, and finally the sealing baffle 3 is driven by the second driving device 9 to be closed.

Here, it should be noted that the first driving device 7 also employs a linear motor, and the linear motor moves the tray 6 linearly in the direction of the operation opening 2.

The light radiation generator 8 is arranged in the box body 1 and right above the tray 6, the shape of the light radiation generator 8 is generally of a tubular structure, and the tubular light radiation generator 8 and the tray 6 are parallel to each other and are fixed in the box body 1 in a horizontal straight line manner.

The sealing baffle 3 is made of heat insulation material or a heat insulation layer is arranged in the sealing baffle 3 and used for retarding heat flow transmission or exchange, the other surface of the box body 1 is also made of the same heat insulation material or is internally provided with the heat insulation layer, and the heat insulation material or the heat insulation layer can be made of materials such as glass fiber, asbestos and the like.

The linear motor, the condenser 4, the light radiation generator 8 and the motor all realize automatic operation through a control center, and the specific structure of the control center is not redundant again.

In the second embodiment, the basic content is the same as that of the first embodiment, and the difference lies in that the opening and closing mode of the sealing baffle 3 can also be that, a connecting rod 10 between the sealing baffle 3 and the linear motor, one end of the connecting rod is fixed on the linear motor, the other end of the connecting rod is fixed on the sealing baffle 3, the connecting rod 10 moves up and down along the driving of the linear motor, sliding chutes are formed in the two sides of the operation opening 2 along the moving direction of the connecting rod 10, the sealing baffle 3 is provided with sliding rails in sliding fit with the sliding chutes, that is, the sealing baffle 3 is installed behind the operation opening 2 and can move up and down along the operation opening 2, so as to realize that the sealing baffle 3 can be sealingly installed in the operation opening 2 in an openable manner, the connecting rod 10 moves up and down along the operation opening 2 by pulling the connecting rod 10, and thus realizing the opening and closing of the sealing baffle 3.

It should be noted that, in the description of the present invention, it is to be understood that the terms "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", etc. indicate the orientation or positional relationship based on the orientation or positional relationship shown in the drawings, which is only for the convenience of describing the present invention and simplifying the description, but does not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and thus, should not be construed as limiting the present invention.

In the present invention, unless otherwise expressly stated or limited, the terms "mounted," "connected," and "fixed" are to be construed broadly and may, for example, be fixedly connected, detachably connected, or integrally formed; can be mechanically or electrically connected; either directly or indirectly through intervening media, either internally or in any other relationship. The specific meaning of the above terms in the present invention can be understood according to specific situations by those skilled in the art.

In the present application, unless expressly stated or limited otherwise, the first feature may be directly on or directly under the second feature or indirectly via intermediate members. Also, a first feature "on," "over," and "above" a second feature may be directly or diagonally above the second feature, or may simply indicate that the first feature is at a higher level than the second feature. A first feature "under," "beneath," and "under" a second feature may be directly under or obliquely under the second feature, or may simply mean that the first feature is at a lesser elevation than the second feature.

Finally, it should be noted that the above embodiments are only used for illustrating the technical solutions of the present invention, and not for limiting the same; although the present invention has been described in detail with reference to the foregoing embodiments, it should be understood by those skilled in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some or all of the technical features may be equivalently replaced; such modifications and substitutions do not depart from the spirit and scope of the embodiments of the present invention.

Claims

1. A low temperature light radiation case for cell culture, its characterized in that, it includes a box (1), box (1) openly is equipped with chamber door (11), operation mouth (2) that have a intercommunication box (1) inner space are opened in chamber door (11), operation mouth (2) are equipped with a sealing baffle (3) that can open and shut, be equipped with condenser (4) that are used for cooling box (1) internal temperature in box (1), be equipped with tray (6) and drive tray (6) first drive arrangement (7) towards operation mouth (2) reciprocating motion that are used for placing culture dish (5) in box (1).

2. The low temperature optical radiation chamber for cell culture according to claim 1, wherein: and a second driving device (9) for driving the sealing baffle (3) to open and close is arranged on the box door (11).

3. The low temperature optical radiation chamber for cell culture according to claim 2, wherein: the tray is characterized in that the first driving device (7) and the second driving device (9) are linear motors, the tray (6) is arranged on the linear motors and is driven by the linear motors to move, one end of the sealing baffle plate (3) is connected to the linear motors, and the other end of the sealing baffle plate can be connected to the operation opening (2) in an opening and closing mode.

4. The low temperature optical radiation chamber for cell culture according to claim 3, wherein: a connecting rod (10) is arranged between the sealing baffle plate (3) and the linear motor, one end of the connecting rod (10) is fixed on the linear motor, the other end of the connecting rod is hinged to the sealing baffle plate (3), and the sealing baffle plate (3) is hinged to the operation opening (2).

5. The low temperature optical radiation chamber for cell culture according to claim 3, wherein: be equipped with between sealing baffle (3) and the linear motor connecting rod (10), connecting rod (10) one end is fixed in the linear motor, and the other end is fixed in sealing baffle (3), opening of operation mouth (2) along the linear motor direction of motion has the spout, sealing baffle (3) are equipped with the slide rail with spout sliding fit.

6. The low temperature optical radiation chamber for cell culture according to claim 1, wherein: the box body (1) is internally provided with a light radiation generator (8) which is arranged right above the tray (6) in a detachable way.

7. The low temperature optical radiation chamber for cell culture according to claim 1, wherein: the sealing baffle (3) is made of a heat insulation material or a heat insulation layer is arranged in the sealing baffle (3).