CN217448714U

CN217448714U - Novel double-channel transcranial magnetic stimulation coil array unit

Info

Publication number: CN217448714U
Application number: CN202221086911.7U
Authority: CN
Inventors: 靳贵平; 陈波静; 邢晓芬; 徐向民
Original assignee: South China University of Technology SCUT
Current assignee: South China University of Technology SCUT
Priority date: 2022-05-06
Filing date: 2022-05-06
Publication date: 2022-09-20
Anticipated expiration: 2032-05-06

Abstract

The utility model discloses a novel binary channels is through cranium magnetic stimulation coil array unit, including upper coil and lower floor's coil, upper coil is including the upper top coil unit that is located the top and set up the upper coil middle part unit in top coil unit bottom, and lower floor's coil is including the lower floor's top coil unit that is located the top and set up the lower floor's coil middle part unit in lower floor's top coil unit bottom, and it is crisscross to be the degree between lower floor's top coil unit and the upper coil middle part unit. The array unit can achieve the purpose of electronically controlling the direction of an electric field, has better focusing performance, simple structure and convenient processing.

Description

Novel double-channel transcranial magnetic stimulation coil array unit

Technical Field

The utility model relates to a transcranial magnetic technology field in electronic communication and brain science branch of academic or vocational study especially relates to a novel binary channels transcranial magnetic stimulation coil array unit.

Background

The Transcranial Magnetic Stimulation (TMS) technology is a painless, noninvasive and relatively safe nerve regulation technology, and directly stimulates nerve cells through a time-varying Magnetic field generated by pulse current introduced into a coil and external tissues of a brain structure so as to achieve the aim of nerve regulation. At present, the method is widely applied to clinical diagnosis and treatment of neurological diseases and mental diseases and exploratory research in the fields of brain science and cognitive science. The stimulation effect of the TMS is influenced by many factors, such as the pulse shape, amplitude, etc. provided by the magnetic field generator, and the structure, orientation, position, current and frequency of the coil, etc. all influence the stimulation performance of the TMS. The coil structure is the focus of TMS research and is also a major factor affecting the stimulation effect.

The existing transcranial magnetic coil structure is a single coil, a multi-channel coil and an array coil.

1. The existing single coil has more structures. Circular coils and splayed coils are commercially available, and have long clinical application time, high safety and poor stimulation depth and focusing performance. In response to the disadvantage of shallow depth of stimulation in conventional coils, the utility model discloses biconical coils (Li, Y., et al, synthetic Study of a New Coil Design With conventional Shield depth-of-overview Coil for transcritical Magnetic stimulation, IEEE Transactions on Magnetics,2018.54(3): p.1-4) and H-coils (Fiocchi, S., et al. deep transcritical Magnetic stimulation for the less the longitudinal field assessment of near systematic stimulation in electronic coils) but With poor deep gradient of electrical field stimulation in adaptive applications.448, deep gradient of electrical field 451. (Cobos Snchez, C., et al., An inverse Boundary element method for designing optimal TMS coils. engineering Analysis with Boundary Elements,2018.88: p.156-169) proposes that the algorithm of the inverse Boundary element optimizes the structure of the biconical coil, so that the stimulation efficiency is higher. However, most of the existing commercial transcranial magnetic coils are single-channel coils, and the corresponding target points of the energized coils are fixed and cannot be changed.

2. In order to combine the advantages of individual coils, a Multi-channel coil is proposed (Koponen, L.M., J.O.Nieminen and R.J.Ilmonimi, Multi-logic transgenic simulation-the term and implementation. brain simulation, 2018.11(4): p.849-855.). The coil is a multi-channel coil formed by combining five single coils with different structures, and the stimulation to different degrees of different parts of the brain is realized by adjusting the size and the direction of exciting current of each channel. However, multi-channel transcranial magnetic coils are complex in design, and although they achieve the purpose of electronically controlling the location of the target, often a superposition of more than three different coils is not suitable for commercialization.

3. Most of the existing coil array units are simple circular coils. The main research direction of the array coil is coil and algorithm combined simulation, and an array coil current scheme with optimal stimulation performance is calculated. The coil array is designed based on the magnetic field vector superposition principle and consists of a plurality of small-size coils, and each unit coil is driven by an independent magnetic field generator, so that various stimulation modes can be realized. However, the existing array coil unit is also the most basic circular coil, the performance of the array coil unit is mainly changed through algorithm optimization, and a coil structure is not designed in a targeted mode.

Disclosure of Invention

In order to solve the problems existing in the prior art, the utility model provides a novel binary channels is through cranium magnetic stimulation coil array unit, through the mode of two-layer coil about setting up, can reach the purpose of electronic control electric field direction, has better focus nature, simple structure, and convenient processing.

In order to achieve the purpose of the invention, the utility model provides a novel binary channels is through cranium magnetic stimulation coil array unit, including upper coil and lower floor's coil, upper coil includes the upper top coil unit that is located the top and sets up the upper coil middle part unit in top coil unit bottom, lower floor's coil includes the lower floor's top coil unit that is located the top and sets up the lower floor's coil middle part unit in lower floor's top coil unit bottom, be degree crisscross between lower floor's top coil unit and the upper coil middle part unit. Preferably, the lower-layer top coil unit and the upper-layer coil middle unit are arranged in a cross shape.

Through the two-channel transcranial magnetic stimulation coil array unit adopting the structure, the upper coil and the lower coil are arranged, so that the direction of the electric field intensity around the coil can be controlled by changing excitation, and the upper coil and the lower coil are of a downward convex structure, so that the electric field intensity outside a focus can be reduced, the stimulation depth is improved, the brain stimulation degree is reduced, and good stimulation and focusing properties are achieved.

To the further improvement of the utility model, the cross-sectional shape of the upper coil top unit is square, and the cross-sectional shape of the upper coil middle unit is U-shaped.

To the utility model discloses a further improvement, the cross sectional shape of lower floor's top coil unit is squarely, and the cross sectional shape of lower floor's coil middle part unit is the U-shaped.

To the further improvement of the utility model, the material of the upper coil is copper.

To the further improvement of the utility model, the material of lower floor's coil is copper.

To the further improvement of the utility model, the upper coil is of a multi-turn structure.

To the further improvement of the utility model, the lower coil is of a multi-turn structure.

It is right to the utility model discloses a further improvement, the number of turns of upper coil is more than the number of turns of lower floor's coil, and the interval between upper coil and the lower floor's coil is adjustable. By the arrangement, the stimulation intensity of the upper coil and the stimulation intensity of the lower coil can be kept consistent.

Further, the number of turns of the upper layer coil is 7 turns, and the number of turns of the lower layer coil is 5 turns.

Further, the coil array unit is adopted to form a coil.

Compared with the prior art, the utility model discloses beneficial effect that can realize at least as follows:

1. the utility model provides a binary channels is through cranium magnetic stimulation coil array unit possesses good focusing performance.

2. The utility model discloses design unit foundation structure based on splayed coil structure, remain the good advantage of splayed coil focusing nature, can reduce the stimulation to cerebral cortex simultaneously.

3. The utility model designs a binary channels through cranium magnetic stimulation coil that possesses bilayer structure can come control coil electric field intensity direction all around through changing the excitation, realizes that electric field direction 360 is adjustable.

4. The utility model discloses a to the performance research of coil, based on the good performance of splayed coil, on this basis, change square project organization into by the circular project organization originally.

5. The utility model provides a coil designs into lower convex structure with focus department, can reduce the electric field intensity outside the focus, promotes amazing degree of depth, reduces the brain amazing degree, is convenient for constitute bilayer structure.

6. The utility model discloses design double-deck binary channels through cranium magnetic stimulation coil array unit based on the stack principle of electromagnetic field, can come control coil electric field intensity direction all around through changing the excitation, and do not change the distribution structure of electric field, possess good irritability and focusing nature.

Drawings

In order to illustrate the embodiments of the present invention or the technical solutions in the prior art more clearly, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the invention, and other drawings can be obtained by those skilled in the art without creative efforts, wherein:

fig. 1 is a schematic structural diagram of a dual-channel transcranial magnetic stimulation coil array unit according to an embodiment of the present invention.

Fig. 2 is a top view of an upper layer coil provided in an embodiment of the present invention.

Fig. 3 is a front view of an upper coil provided in an embodiment of the present invention.

Fig. 4 is a left side view of an upper coil provided in an embodiment of the present invention.

Fig. 5 is a top view of a two-channel transcranial magnetic stimulation coil array unit according to an embodiment of the present invention.

Fig. 6 is a front view of a dual-channel transcranial magnetic stimulation coil array unit according to an embodiment of the present invention.

Fig. 7 is a side view of a dual channel transcranial magnetic stimulation coil array unit according to an embodiment of the present invention.

Fig. 8 is a single-channel simulation result diagram in an embodiment of the present invention.

Fig. 9 is a schematic diagram of a dual channel simulation result in an embodiment of the present invention.

Fig. 10 is an exemplary diagram of regulating the direction of the electric field in the embodiment of the present invention.

Fig. 11 is a schematic diagram of a simulation result after a size change in an embodiment of the present invention.

In the figure, an upper coil 1, an upper top coil unit 11 and an upper coil middle unit 12; a lower layer coil 2, a lower layer top coil unit 21, and a lower layer coil middle unit 22.

Detailed Description

In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the drawings in the embodiments of the present invention are combined below to clearly and completely describe the technical solutions in the embodiments of the present invention, and obviously, the described embodiments are some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work are all the protection scope of the present invention.

In addition, the descriptions related to "first", "second", etc. in the present invention are only for description purposes, not specifically referring to the order or sequence, and are not intended to limit the present invention, but only to distinguish the components or operations described in the same technical terms, and are not to be construed as indicating or implying any relative importance or implicit indication of the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include at least one such feature. In addition, the technical solutions in the embodiments may be combined with each other, but it must be based on the realization of those skilled in the art, and when the technical solutions are contradictory or cannot be realized, the combination of the technical solutions should not be considered to exist, and is not within the protection scope of the present invention.

The utility model provides a novel binary channels is through cranium magnetic stimulation coil array unit, the improvement of going on splayed through cranium magnetic stimulation coil's basis, the overall structure of coil array unit please refer to and draw together fig. 1-7, and the design structure of binary channels "ten" style of calligraphy is considered to this coil foundation structure, changes into square structure by the circular design structure of splayed coil originally, and the plan view is shown in fig. 2. Meanwhile, in order to enhance the focusing performance and the stimulation depth of the coil, reduce the stimulation intensity of the cerebral cortex and reduce the brain injury, the middle structure of the coil is designed into a downward convex structure, as shown in fig. 3 and 4. This lower protruding formula coil unit structure strengthens amazing degree of depth greatly on the basis of taking into account the good focus nature of splayed coil, and its electric field distribution simulation result is like figure 8 to the realization is amazing to the deep of brain, the utility model discloses but wide application in medical equipment technical field.

In some embodiments of the present invention, the bottom side of the upper coil 1 is 50mm in length and 20mm in height, as shown in fig. 2 and 3.

In some embodiments of the present invention, the coil array unit is made of copper and has a conductivity of 5.8 × 10 ⁷ And (5) S/m. The selection of the copper material ensures that the current carrying capacity of the coil array unit is not influenced when high-frequency and large-amplitude current is introduced.

The utility model discloses a coil array unit is bilayer structure, and through the excitation size and the directional control coil electric field intensity distribution all around of controlling every passageway, including upper coil 1 and lower floor's coil 2, lower floor's coil 2 is located upper coil 1 below, and crisscross resynthesis double-deck "cross" structure between upper coil 1 and lower floor's coil 2, and upper and lower floor's coil structure is not continuous, as shown in FIG. 1. According to the superposition principle of electromagnetic fields, the direction of the electric field can be rotated by 360 degrees at will by changing the excitation combination of the two channels.

Specifically, upper coil 1 is connected and is located upper coil middle part unit 12 of upper top coil unit 11 bottom including upper top coil unit 11 and both ends that are located the top with upper top coil unit 11, lower floor's coil 2 is connected and is located lower floor's coil middle part unit 22 of lower floor's top coil unit 21 bottom including lower floor's top coil unit 21 and both ends that are located the top with lower floor's top coil unit 21, it is 90 degrees crisscross to be between lower floor's top coil unit 21 and the upper coil middle part unit 12, upper coil middle part unit 12 and lower floor's coil middle part unit 22 are the cross and arrange preferentially. The upper layer top coil unit 11 is located above the lower layer top coil unit 21 with a gap between the upper layer coil middle unit 12 and the lower layer coil middle unit 22.

In some embodiments of the present invention, due to the double-layer structure, the top view of the two-channel transcranial magnetic stimulation coil array unit is as shown in fig. 5, the upper coil 1 is far away from the stimulation point, and the corresponding axial stimulation intensity is lower than the corresponding axial stimulation of the lower coil 2. In order to solve the problem, the number of turns of the upper coil 1 is increased, and under the condition that the number of turns of the upper coil 1 is more than that of the lower coil 2, the distance between the upper coil 1 and the lower coil 2 is adjusted to achieve the consistency of stimulation. And adjusting the interlayer spacing, and finding that the axial stimulation intensity of the upper coil 1 is greater than that of the lower coil 2 after the upper coil 1 and the lower coil 2 are consistent in stimulation intensity to the top central point of the cerebral cortex. In order to solve the problem, the present invention shortens the width of the middle structure of the upper coil (i.e. the width of the upper coil middle unit 12 is smaller than the width of the lower coil middle unit 22), as shown in fig. 6 and 7. The utility model discloses guaranteed that upper coil 1 and lower floor's coil 2 are in the amazing uniformity and the ascending amazing intensity uniformity of axial of focus position to guarantee that the electric field distribution around the coil is unchangeable, change the excitation combination and just change electric field direction and size.

In some embodiments of the present invention, the number of turns of the upper coil 1 is 7 turns, and the number of turns of the lower coil is 5 turns, it can be understood that other values can be set in other embodiments.

The utility model discloses in some of them embodiments, use simulation software sim4life to verify the coil performance of design, in order to accelerate emulation speed and make things convenient for comparison performance to spherical model replaces the human brain, and it is isotropic to assume, uses sim4life from the human database in area to set up electromagnetic characteristic for the bulb model. Excitation is added to the upper layer channel, the excitation size is set to be 3kA, the frequency is 3kHz, the simulation result is shown in figure 8, and the electric field distribution is similar to a splayed coil. In order to make the result clearer, the coils are not shown in the subsequent simulation diagram, the upper layer coils are called channels (i), and the lower layer coils are called channels (ii), as shown in fig. 8. Exciting the channels I and II with the same size, wherein the exciting size is set to be 3kA, and the frequency is 3 kHz; the simulation result is shown in fig. 9, the electric field focus is at the center of the coil, the electric field is inclined by about 45 degrees compared with a single channel, and the stimulation effect is similar to that of the single channel. In order to verify the regulation performance of the double channels, 3kA excitation is introduced into the channel I, the excitation size of the channel II is changed, the frequency is 3kHz, simulation results are shown in figure 10, and it can be seen from the results that the electric field focus is still at the center of the coil, and the electric field inclines by about 30 degrees (figure 10A, B) and about 60 degrees (figure 10C, D) respectively compared with a single channel. From the simulation result, the utility model discloses the coil can realize 360 arbitrary rotations of electric field direction, and does not change electric field distribution.

The embodiment of the utility model provides a coil array unit can reach the purpose of electronic control electric field direction, has fine focus nature and irritability, simple structure, convenient processing.

The utility model discloses a coil can regard as the binary channels coil to use, also can reduce the size as coil array unit, and the equal proportion enlargies and reduces the coil and does not change the electric field distribution around the coil, just also does not influence the stimulation performance of coil yet. The coil is amplified by one time in equal proportion, the excitation with the same size is introduced into the two channels, the excitation size is set to be 3kA, the frequency is 3kHz, and the simulation result is shown in FIG. 11. The simulation results compared to fig. 9 show that the electric field distribution around the coil is substantially uniform, indicating that dimensional changes do not affect the coil function. The utility model relates to a binary channels coil's advantage is that electric field direction 360 is adjustable, and the advantage as the array unit can be joined in marriage the amazing arbitrary position of algorithm after the component array.

The previous description of the disclosed embodiments is provided to enable any person skilled in the art to make or use the present invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the generic principles defined herein may be applied to other embodiments without departing from the spirit or scope of the invention. Thus, the present invention is not intended to be limited to the embodiments shown herein but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.

Claims

1. The utility model provides a novel binary channels is through cranium magnetic stimulation coil array unit, a serial communication port, including upper coil (1) and lower floor's coil (2), upper coil (1) is including upper top coil unit (11) that are located the top and upper coil middle part unit (12) of setting in top coil unit (11) bottom, lower floor's coil (2) are including lower floor's top coil unit (21) that are located the top and lower floor's coil middle part unit (22) of setting in lower floor's top coil unit (21) bottom, it is 90 degrees crisscross between lower floor's top coil unit (21) and upper coil middle part unit (12).

2. The novel two-channel transcranial magnetic stimulation coil array unit according to claim 1, wherein the cross-sectional shape of the upper layer top coil unit (11) is square, and the cross-sectional shape of the upper layer coil middle unit (12) is U-shaped.

3. The novel two-channel transcranial magnetic stimulation coil array unit according to claim 1, wherein the cross-sectional shape of the lower-layer top coil unit (21) is square, and the cross-sectional shape of the lower-layer coil middle unit (22) is U-shaped.

4. The novel two-channel transcranial magnetic stimulation coil array unit according to claim 1, wherein the upper coil (1) is made of copper.

5. The novel two-channel transcranial magnetic stimulation coil array unit according to claim 1, wherein the lower coil (2) is made of copper.

6. The novel dual-channel transcranial magnetic stimulation coil array unit according to claim 1, wherein the upper coil (1) is of a multi-turn structure.

7. The novel dual-channel transcranial magnetic stimulation coil array unit according to claim 6, wherein the lower coil (2) is of a multi-turn structure.

8. The novel two-channel transcranial magnetic stimulation coil array unit according to claim 7, wherein the number of turns of the upper coil (1) is larger than that of the lower coil (2), and the distance between the upper coil (1) and the lower coil (2) is adjustable.

9. The novel two-channel transcranial magnetic stimulation coil array unit according to claim 6, wherein the number of turns of the upper-layer coil (1) is 7, and the number of turns of the lower-layer coil (2) is 5.

10. The novel dual channel transcranial magnetic stimulation coil array unit according to any one of claims 1-9, wherein the coil array unit is adopted to form a coil.