CN217409572U - Infrared assembly for treating skin - Google Patents

Abstract

The utility model provides an infrared subassembly (100) for treating skin, include: an infrared-emitting film (11); electrodes (12) electrically connected to the infrared emission films (11), respectively; external leads (13) respectively connected with the electrodes (12); the infrared assembly (100) further comprises a carrier substrate (10), the infrared emission film (11) being at least partially arranged on a surface of the carrier substrate (10); wherein the wavelength of the infrared rays emitted by the infrared emission film (11) is 1-25 μm, and the heating temperature of the infrared emission film (11) is 30-60 ℃.

Description

Infrared assembly for treating skin

Technical Field

The utility model relates to an infrared subassembly for treating skin especially relates to an infrared subassembly for treating skin wart.

Background

The dermatosis is related to skin diseases, is one of common diseases and frequently encountered diseases which seriously affect the health of people, and has the characteristics of high morbidity, high disability rate, strong infectivity, long treatment time and the like. With the increasing environmental pollution, the incidence of skin diseases is increasing. The reported dermatosis is a disease with the highest morbidity, the highest disability rate and the strongest infectivity in the history of human in the 21 st century. The data shows that the national dermatological drug market scale in 2018 reaches 167.31 billion yuan, which is a 4.3% increase on a par with the same. According to the research report on Chinese market assessment of skin disease drugs and investment direction (2018), it is shown that about 4.2 hundred million people suffer from skin diseases worldwide, wherein about 1.5 million patients exist in China.

More and more people suffering from skin diseases are concerned about symptomatic treatment. For example, cutaneous warts are a common cutaneous Human Papilloma Virus (HPV) infection, with an average prevalence of 3-13% in the population, and higher in children. Daily activities and quality of life can be significantly affected by local discomfort, restricted movement, etc. The common clinical treatment methods include freezing, electrocautery, laser surgery, external salicylic acid and the like, but the effects and the side effects are different. Generally, the cure rate is not more than 50%. Intractable warts are challenging because of cosmetic problems, resistance to treatment, and frequent recurrences that are present in the patient himself, the dermatologist, and the physician.

SUMMERY OF THE UTILITY MODEL

The utility model provides an infrared subassembly for treating skin wart can effectively solve above-mentioned problem.

The utility model discloses a realize like this:

an infrared assembly for treating skin warts, comprising:

an infrared-emitting film;

electrodes electrically connected to the infrared emission films, respectively;

external leads respectively connected with the electrodes;

the infrared assembly further comprises a bearing substrate, and the infrared emission film is at least partially arranged on the surface of the bearing substrate;

wherein the wavelength of the infrared rays emitted by the infrared emission film is 1-25 μm, and the heating temperature of the infrared emission film is 30-60 ℃.

The beneficial effects of the utility model are that: the utility model discloses a device does not observe other side effects except that children's participant complains to have mild and the good burning sensation of tolerance. In addition, the device of the present invention showed no other side effects except for mild burning sensation and good tolerance complaints of the children participants. In addition, the infrared treatment device of the utility model has high energy utilization rate and high infrared radiation ratio; the equipment is portable and portable; is soft and bendable, and is suitable for different affected parts and different sizes of affected parts; can be applied to affected part for treatment, so that infrared radiation can act on affected part as much as possible to avoid attenuation (infrared radiation can be gradually attenuated in air). Finally, the utility model discloses accessible APP's control can conveniently, accurately control treatment temperature, time, record patient use time quantum, can upload the affected part picture simultaneously, makes things convenient for the doctor to trail whole treatment process.

Drawings

In order to more clearly illustrate the technical solution of the embodiments of the present invention, the drawings which are required to be used in the embodiments will be briefly described below, it should be understood that the following drawings only illustrate some embodiments of the present invention and therefore should not be considered as limiting the scope, and that for those skilled in the art, other related drawings can be obtained according to these drawings without inventive efforts.

Fig. 1 is a schematic structural diagram of an infrared module for treating skin warts, according to an embodiment of the present invention.

Fig. 2 is a side view of an infrared assembly for treating skin warts as provided by an embodiment of the invention.

Fig. 3 is a far infrared spectrum of the release of an infrared assembly for treating skin warts as provided by an embodiment of the present invention.

Fig. 4 is a schematic structural diagram of an external controller in an infrared device for treating skin warts according to an embodiment of the present invention.

In fig. 5, c is a photograph of the powered patch covered on the finger wart by the infrared component for treating skin wart provided by the embodiment of the present invention, and d is a corresponding infrared image by a temperature recorder.

FIG. 6 is a photographic comparison of treatment progress and results within 3 months for representative patients with refractory warts.

FIG. 7 is a photograph comparing the progress and results of treatment in 3 months for representative patients with refractory warts.

FIG. 8 is a photograph comparing the progress and results of treatment in 3 months for a representative patient with drusen.

Figure 9 is a comparison of the lesion excision pathology and immunofluorescence of the participants of figure 8 before (left) and two weeks after (right) treatment.

Fig. 10 is a wearable device for treating skin warts according to an embodiment of the present invention.

Detailed Description

To make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the drawings of the embodiments of the present invention are combined to clearly and completely describe the technical solutions of the embodiments of the present invention, and obviously, the described embodiments are some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention. Thus, the following detailed description of the embodiments of the present invention, presented in the accompanying drawings, is not intended to limit the scope of the invention, as claimed, but is merely representative of selected embodiments of the invention. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.

In the description of the present invention, the terms "first" and "second" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implying any number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of the present invention, "a plurality" means two or more unless specifically limited otherwise.

Referring to fig. 1, an embodiment of the present invention provides an infrared assembly 100 for treating skin warts, comprising:

an infrared emission film 11, wherein the wavelength of infrared rays emitted by the infrared emission film 11 is 1 μm to 200 μm;

electrodes 12 electrically connected to the infrared emission films 11, respectively;

and external leads 13 respectively connected to the electrodes 12.

The infrared component 100 is covered on the position of skin diseases caused by human body skin wart infection, and can emit infrared light with the temperature of 30-60 ℃ and the wavelength of 1-200 mu m after the power supply is switched on, thereby effectively removing the human body skin wart and improving the local immunity.

The electrode 12 and the external lead 13 may be an integrated structure or an independent structure, which is not limited herein. The electrodes 12 may be arranged in parallel and spaced apart.

The heating temperature of the infrared emission film 11 may be further 35 to 45 ℃. Preferably, the wavelength of the infrared ray emitted by the infrared emission film 11 is simulated human body middle and far infrared, that is, 1 μm to 25 μm of middle infrared light, and the heating temperature of the infrared emission film 11 is 39 ℃ to 43 ℃. More preferably, the infrared emission film 11 emits infrared rays having a wavelength similar to human far infrared, i.e., a medium-far infrared light (more than 80%) having a wavelength of 5 μm to 15 μm, and the infrared emission film 11 is heated at a temperature of 40 ℃ to 42 ℃. The infrared emission film 11 is a flexible film, and the material of the infrared emission film 11 is not limited, and any material that is non-toxic and can emit infrared light may be used. In one embodiment, the infrared emission film 11 is made of carbon-based conductive ink.

Specifically, 100-1000 times of expanded graphite is crushed to D50 which is 200 mu m; then, forming a conductive agent by the expanded graphite and the conductive carbon black according to the mass ratio of 6-10: 1; 5-20 wt% of a conductive agent, 20-30 wt% of acrylic resin, rheological additive castor oil (the amount is wt 3-6% of the conductive agent), silane coupling agent (the amount is 0.5-2 wt% of the conductive agent), and the balance of a mixed solvent composed of terpineol and ethanol according to the mass ratio of 3:7, so as to obtain a mixture; stirring the mixture for more than 10 minutes by using a high-speed stirrer to obtain uniform carbon-based conductive ink precursor dispersion without bubbles; ball-milling the carbon-based conductive ink precursor dispersion liquid until the fineness is lower than 20 mu m, and obtaining the carbon-based conductive ink according to the viscosity of 1000-13000 mPa & s in different printing modes; then, the carbon-based conductive ink is subjected to gravure printing, screen printing, coating and the like on a bearing substrate 10 to obtain a wet film, and then the wet film is dried and cured at a low temperature (200 ℃) to obtain the infrared emission film 11.

In one example, 450 times the expanded graphite was pulverized to D50 ═ 200 μm; then, forming a conductive agent by the expanded graphite and the conductive carbon black according to the mass ratio of 8: 1; 10 wt% of conductive agent, 25 wt% of acrylic resin, rheological additive castor oil (the amount is 5 wt% of the conductive agent), silane coupling agent (the amount is 1 wt% of the conductive agent), and the balance of mixed solvent composed of terpineol and ethanol according to the mass ratio of 3:7 to obtain a mixture; stirring the mixture for more than 10 minutes by using a high-speed stirrer to obtain uniform carbon-based conductive ink precursor dispersion without bubbles; ball-milling the carbon-based conductive ink precursor dispersion liquid until the fineness is lower than 20 mu m, and obtaining the carbon-based conductive ink according to the viscosity of 1000-13000 mPa & s in different printing modes; and then coating the carbon-based conductive ink on a bearing substrate 10 to obtain a wet film, and drying and curing at a low temperature (<200 ℃) to obtain the infrared emission film 11. Referring to fig. 3, fig. 3 shows a far infrared spectrum emitted from the infrared emission film 11 provided in this embodiment, wherein the wavelength of the far infrared spectrum is mainly in a range of 5-15 micrometers (more than 80%) which is very close to the range of normal human body radiation (i.e., the far infrared spectrum emits infrared rays imitating human bodies). The expanded graphite forms graphene, carbon atoms vibrate and collide with each other under the condition of electrification to generate heat energy, the heat energy is mainly radiated in a far infrared ray mode with the wavelength of 5-15 mu m, and the effective electric heat conversion efficiency reaches more than 99%. The infrared with the wavelength of 5-15 μm is considered as 'life light wave', is matched with the vibration frequency wave band of human cell molecules, and is easy to absorb by human bodies.

In other embodiments, the infrared module 100 may further include a carrier substrate 10, and the infrared emission film 11 is at least partially disposed on a surface of the carrier substrate 10. The bearing substrate 10 is a flexible film such as PI, PET, a silica gel film, polyester fabric, nylon fabric, non-woven fabric, polyurethane fabric and leather; or hard sheet structures such as glass sheets, mica sheets or ceramic sheets. The carrier substrate 10 may be cut to fit various parts of the human body, such as fingers, toes, joints, etc., and will not be described in detail herein.

Further, in other embodiments, the infrared module 100 may further include an infrared reflection film 17 disposed on a surface of the carrying substrate 10 away from the infrared emission film 11, for reflecting the infrared rays emitted from the infrared emission film 11 in the same direction.

Further, in other embodiments, the infrared module 100 may further include a temperature sensor 15 disposed between the infrared emission film 11 and the carrier substrate 10 for acquiring a heating temperature of the infrared emission film 11. It can be understood that the temperature of the infrared emission film 11 can be obtained in real time through the temperature sensor 15, the temperature can be accurately controlled, and the skin can be prevented from being scalded due to overheating.

Further, in other embodiments, the infrared assembly 100 may further include a gauze 14 covering the surface of the infrared emission film 11 away from the carrier substrate 10, so as to prevent the graphite from directly contacting the skin during treatment.

Further, in other embodiments, the infrared assembly 100 may further include a fixing member 16 disposed on the carrier substrate 10 for fixing the infrared emission film 11 to different parts of human skin. The fixing member 16 is a hook and loop fastener or a buckle.

Further, in other embodiments, the infrared module 100 may further include an external connector 18 or an external interface connected to the external lead 13 for connecting with an external controller 200. In other embodiments, the external connector 18 or external interface is embedded in the carrier substrate 10 and partially exposed, thereby preventing damage.

Referring to fig. 4, an embodiment of the present invention provides an infrared device for treating skin warts, including:

the infrared component 100; and

the external controller 200, the external controller 200 includes a connection jack 20. The external connector 18 is inserted into the connection jack 20 to connect the external controller 200 to the infrared module 100.

Further, the external controller 200 includes a switch 21 and a control button 22. The control button 22 can adjust temperature and time. The optimum temperature and time may be set in the off-board controller 200. Generally, the optimal temperature is 40-42 ℃, and the optimal treatment time is 30-60 minutes each time. However, for different individuals, the temperature can be reduced by controlling the button 22 when the temperature is too high, and the temperature can be increased by controlling the button 22 when the temperature is too low.

In other embodiments, the external controller 200 may further have a memory module (not shown). The memory module is used for storing basic information of the patient and treatment parameter information. The basic information includes a name, a disease location, and the like. The treatment parameter information comprises an optimal treatment temperature, an optimal treatment time, the total time length of treatment and the like. When the patient name is entered, the relevant parameter information can be retrieved for treatment without additional adjustment. The external controller 200 may further include a camera module (not shown) for taking pictures of different time periods according to the treatment time period of the patient and storing the pictures in the memory module. Specifically, the external controller 200 may control the camera module to obtain the photos of the affected part according to the interval time (e.g., every week or month), and present the photos before and after the treatment to the doctor for comparison, thereby facilitating the adjustment of the treatment scheme in time.

The infrared device is applied to treatment of skin warts:

is filed in China clinical trial registration center (ChiCRT2000037609), and the experimental design is to use the utility model provides an infrared device to treat intractable warts and observe the clinical curative effect and the safety. In the study, refractory warts are selected, 36 in all cases and 2 in all cases are exfoliated. The final 34 cases were included in the analysis. 20 men and 14 women. The mean age was 23.9 ± 11.4, the maximum age was 46 years, and the minimum age was 7 years. The subjects were treated externally for 40 minutes at 42 ℃ per day (FIG. 5). The course of treatment was recorded and photographed. Side reactions in the experiment were also observed and recorded. Efficacy results were evaluated at 12 weeks of treatment and defined as Complete clearance (CC, reduction of 100% in wart size and number, restoration of normal skin at close examination), near Complete clearance (NCC, 75% -99%), partial clearance (PCC, 50% -74%) and no response (reduction less than 50%). Treatment success was defined as CC and NCC. Digital photographs of the warts were taken at baseline and outcome assessment, respectively, as shown below.

The overall remission rate was found to be 82.4%, with 95% CI of 65.2-93.2, with a lower limit of 65.2% higher than 58% of the current standard of treatment (power ═ 0.76). The differences of remission rates of different parts, different age groups and different sexes are compared by using Fisher's exact probability method, and the differences are found to have no statistical significance (figure 6). FIG. 6 is a photograph of treatment progress and results within 3 months of a representative patient with refractory warts. The lesions are completely cleared from left to right before treatment, 1 month and 2 months after treatment and 3 months after treatment respectively.

TABLE 1 therapeutic effect after 12 weeks of treatment

Note: overall remission rate (OR) ═ number of curative cases + number of significant cases)/total cases treated

TABLE 2 analysis of the therapeutic effects of different parts

TABLE 3 analysis of the therapeutic effects of different age groups

TABLE 4 analysis of the therapeutic effects of different parts

For the most challenging nail warts, 12 of 13 participants were completely cleared. Especially, children patients are easy to bite and hurt the nail part, the pain of the treatment by the traditional means is hard to endure, the wart body invades and grows inwards along with the treatment, and the device of the scheme has the most difficult of the virus wart, achieves good effect, and is comfortable and easy to accept (figures 7-8). FIG. 7 is a photograph of treatment progress and results within 3 months of a representative patient with refractory warts. From left to right, the lesions are completely cleared before, 1 month, 2 months and 3 months after treatment. FIG. 8 is a hallux hyponychium which causes the downward invasive growth of the wart and the disfigurement and hyperplasia of the nail plate after long-term treatment. The device can be used for treating verruca removal, and the toenails grow normally.

Fig. 9 shows that participants in fig. 8 showed significantly increased recruitment of red fluorescence signals at the site of the lesion compared to the left, before (left) and after (right) treatment of the lesion excision pathology of the lesion, and by immunofluorescence examination, indicating that the site of the lesion is aggregated with activated langerhans cells and enhanced local immunity.

To sum up, the utility model discloses a device can be recruited, and activation langerhans cells gets into the skin damage position, improves it and draws the ability of passing to viral antigen, improves local immunity, clears away the virus, cures skin infection.

Comparative example:

the comparative example takes the metal wire electrothermal film as the heating chip to carry out a contrast experiment. Total 20 cases, 5 cases with abscission, and 15 final cases were analyzed. The number of the male patients is 11, and the number of the female patients is 4. The age is 20-30 years. The treatment was carried out at 42 ℃ for 40 minutes per day. The results showed that the overall remission rate was only 46.7% with 95% CI ranging from 21.3 to 73.5. During the treatment, 6 people feedback slight burning feeling, and no other side effect is observed. In contrast, the overall therapeutic effect of the far infrared device prepared by the method is obviously superior to that of a metal wire electrothermal film device.

TABLE 5 curative effect of electrothermal film of metal wire after 12 weeks of treatment

Note: overall remission rate (OR) ═ number of curative cases + number of significant cases)/total cases treated

Referring to fig. 10, fig. 10 is a view of a wearable device 300 for treating skin warts according to an embodiment of the present invention, where the wearable device 300 is a sock. It is to be understood that the wearable device 300 is not limited to socks, but may be gloves, scarves, hats, coats, knee pads, wristbands, and the like, without limitation thereto.

Specifically, the wearable device 300 includes a body 30, an infrared module 100 disposed inside the body 30, and a control module 31. It is understood that the infrared assembly 100 is not limited to be disposed at the position corresponding to the toes, but may be disposed at the sole or other positions, which is not limited herein. The control module 31 is electrically connected to the infrared module 100, and is configured to control the infrared module 100 to emit infrared rays, and to enable the heating temperature of the infrared module to reach 30-60 ℃. The control module 31 may set a plurality of fixed treatment modes. For example, the control module 31 may set the heating temperature to 42 ℃ and the heating time to 40 minutes; when the switch is opened, it automatically executes the treatment mode. In other embodiments, the control module 31 may further include a communication module (not shown), and a user may communicate with the communication module through a smart terminal to execute different control commands. For example, the communication module is a bluetooth module, and after a user downloads APP through a smart phone and connects with the smart phone via bluetooth, the user controls the infrared module 100 to execute a corresponding instruction by inputting heating temperature and heating time.

The embodiment of the utility model provides a wearable system for treating skin wart who further provides, include:

a body 30;

the infrared component 100 is arranged in the body 30, and the wavelength of infrared rays emitted by the infrared component 100 is 1-200 μm; and

the control module 31 is arranged on the body 30 and is used for controlling the infrared component 100 to emit infrared rays and enabling the heating temperature of the infrared component to reach 30-60 ℃, and the control module 31 further comprises a communication module;

install APP's intelligent terminal, it passes through communication module with control module group 31 communication makes control module group 31 carries out different control command.

Of course, the APP may store basic information of the patient as well as treatment parameter information. The basic information includes a name, a disease location, and the like. The treatment parameter information comprises an optimal treatment temperature, an optimal treatment time, the total time length of treatment and the like. The APP can be further used for uploading pictures of affected parts of patients in different treatment periods. This photo can upload to the high in the clouds, and the doctor can compare the photo around will treating through the high in the clouds to be favorable to the doctor in time to adjust the treatment scheme, and feed back to corresponding patient.

The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention, and various modifications and changes may be made by those skilled in the art. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims (10)

1. An infrared assembly (100) for treating skin, comprising:

an infrared-emitting film (11);

electrodes (12) electrically connected to the infrared emission films (11), respectively;

external leads (13) respectively connected with the electrodes (12);

the infrared assembly (100) further comprises a carrier substrate (10), the infrared emission film (11) being at least partially arranged on a surface of the carrier substrate (10);

wherein the wavelength of the infrared rays emitted by the infrared emission film (11) is 1-25 μm, and the heating temperature of the infrared emission film (11) is 30-60 ℃.

2. The infrared assembly for treating the skin according to claim 1, wherein said carrier substrate (10) is a PI, PET, silicone film, polyester fabric, nylon fabric, non-woven fabric, polyurethane fabric, leather, glass sheet, mica sheet or ceramic sheet.

3. The infrared assembly for treating the skin according to claim 1, wherein said infrared emitting film (11) is obtained by obtaining a wet film by gravure printing, screen printing or coating carbon-based conductive ink on a supporting substrate (10), and then drying and curing at a low temperature.

4. The infrared assembly for treating the skin according to claim 1, further comprising a temperature sensor (15) disposed between said infrared-emitting film (11) and said carrier substrate (10) for acquiring the heating temperature of said infrared-emitting film (11).

5. The infrared assembly for treating skin according to claim 1, further comprising a gauze (14) covering a surface of said infrared-emitting film (11) remote from said carrier substrate (10) so as to avoid direct contact between graphite and skin during treatment.

6. The infrared assembly for treating skin according to claim 1, further comprising fixing members (16) disposed on said carrier substrate (10) for fixing said infrared-emitting film (11) to different portions of human skin.

7. Infrared assembly for treating the skin according to claim 6, characterized in that said fixing means (16) are velcro or snap fasteners.

8. Infrared assembly for treating the skin according to claim 1, characterized in that said carrier substrate (10) has a shape adapted to the shape of different parts of the human body.

9. The infrared assembly for treating skin according to claim 1, further comprising an external connector (18) connected to said external lead (13) for connection to an external controller (200).

10. Infrared assembly for treating the skin according to claim 9, characterized in that said external connector (18) is embedded in said carrying base (10) and partially exposed.

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