CN217341846U

CN217341846U - Be used for cell culture centrifugal device

Info

Publication number: CN217341846U
Application number: CN202221519225.4U
Authority: CN
Inventors: 郝国梁; 王功新
Original assignee: Henan Pevi Technology Co ltd
Current assignee: Henan Pevi Technology Co ltd
Priority date: 2022-06-17
Filing date: 2022-06-17
Publication date: 2022-09-02
Anticipated expiration: 2032-06-17

Abstract

The utility model discloses a be used for cell culture centrifugal device, fix the device barrel in the base upper end including the base and through the bracing piece, tip fixed mounting has driving motor under the device barrel, and the driving motor output shaft extends to in the device barrel and fixedly connected with bottom plate, all is equipped with the test tube recess on the bottom plate, and the bottom plate upper end is through a pair of pole setting fixedly connected with loading board. The utility model, by arranging the sliding plate, the fixing mechanism, the limiting mechanism, the driving mechanism and the like, and clamping and fixing the cell test tube by utilizing the two groups of arc-shaped fixing splints, ensures the stability of the cell test tube in the cell centrifugation process and avoids the defect that the cell test tube is unstable due to spring shake; and be provided with the bottom plate for the lower tip of cell test tube and carry out the bearing, compare in prior art and only set up a loading board, more can increase the stability of cell test tube in centrifugal process, more can avoid cell pollution.

Description

Be used for cell culture centrifugal device

Technical Field

The utility model relates to a cell culture technical field especially relates to a be used for cell culture centrifugal device.

Background

The cell separation technology is a branch of cell culture, centrifugation is a basic means for researching cell nucleus, mitochondria, Golgi body, lysosome and microbody and various macromolecules, and the cells need to be centrifugally rotated, but in the prior art, the cultured cells are generally taken out from an incubator and then transferred to a separate centrifugal device for centrifugation, so that the operation is complex, the stability of a cell culture test tube in the centrifugation process is poor, the possibility of cell pollution is increased, and the existing centrifugal device also has the problems of complex structure and high operation cost.

To above-mentioned problem, the utility model patent granted for application number CN201920599279.8 discloses a centrifugal equipment for cell culture, including casing, motor, transmission shaft, driven shaft, centrifuge bowl, loading board and apron, its characterized in that: the centrifugal pump is characterized in that a first bearing is arranged on the inner wall of the shell, the motor is arranged on the outer wall of the shell, the transmission shaft is arranged in the shell, one end of the transmission shaft is connected with the motor, the other end of the transmission shaft is arranged in the first bearing, the driven shaft vertically penetrates through a second bearing, the centrifugal cylinder is arranged in the shell, and the bearing plate is movably arranged on the cushion block.

Although the problem of poor stability of the cell culture test tube in the centrifugation process is solved to a certain extent in the patent, certain defects still exist, firstly, the stability of the test tube is increased by adopting a mode of clamping the test tube by spring elasticity, and when cells are centrifuged, the spring can shake to a certain extent due to the existence of centrifugal force, so that the cell test tube still has certain instability; secondly, it only is provided with a loading board, and the lower tip of cell test tube is in unsettled state completely, and during the cell centrifugation process, the lower tip of cell test tube can produce certain rocking naturally, still has the possibility of cell pollution.

SUMMERY OF THE UTILITY MODEL

The utility model aims at solving the defects existing in the prior art and providing a centrifugal device for cell culture.

In order to realize the purpose, the utility model adopts the following technical scheme:

a centrifugal device for cell culture comprises a base and a device cylinder body fixed at the upper end of the base through a support rod, wherein a driving motor is fixedly installed at the lower end of the device cylinder body, an output shaft of the driving motor extends into the device cylinder body and is fixedly connected with a bottom plate, test tube grooves are formed in the bottom plate, the upper end of the bottom plate is fixedly connected with a bearing plate through a pair of vertical rods, test tube through grooves are formed in the bearing plate, cell test tubes are placed in the test tube through grooves, the bottoms of the cell test tubes are positioned in the test tube grooves, a pair of sliding plates are symmetrically arranged on two sides of the upper end of the bearing plate, fixing mechanisms for fixing the cell test tubes are symmetrically arranged on the pair of sliding plates, limiting mechanisms for limiting the sliding plates to horizontally slide are installed on the side walls of the sliding plates, a pair of fixing plates are symmetrically and fixedly connected with two sides of the upper end of the bearing plate, and driving mechanisms for driving the sliding plates to slide are installed on the fixing plates, the device barrel upper end portion articulates there is the apron, device barrel upper end portion lateral wall symmetry is fixed and is provided with a pair of pull ring.

Preferably, fixed establishment includes the arc solid fixed splint, the arc solid fixed splint all establish in the sliding plate upper end and extend to test tube groove, and a pair of arc solid fixed splint on the sliding plate are symmetrical each other.

Preferably, the limiting mechanism comprises sliding grooves and bending sliding rods, the two groups of sliding grooves are symmetrically formed in the upper end of the bearing plate, one ends of the bending sliding rods are fixedly connected to the side walls of the sliding plates, and the other ends of the bending sliding rods are connected in the sliding grooves in a sliding mode.

Preferably, the driving mechanism comprises a threaded column and a knob, the threaded column penetrates through the fixed plate and is in threaded connection with the fixed plate, the inner end of the threaded column is rotatably connected with the sliding plate, and the knob is fixedly connected to the outer end of the threaded column.

Preferably, an arc-shaped rubber pad is fixedly arranged on the inner arc surface of the arc-shaped fixing clamping plate.

Preferably, the outside cover of knob is equipped with anti-skidding gum cover, anti-skidding line has been seted up on anti-skidding gum cover surface.

The utility model discloses following beneficial effect has:

1. through setting up sliding plate, fixed establishment, stop gear and actuating mechanism etc., before carrying on the cell test tube centrifugal operation, rotate the knob first, make the threaded column rotate and drive a pair of mutual approaching, thus utilize two sets of arc-shaped fixed splint to carry on the centre gripping to the cell test tube fixedly, has replaced the spring force among the prior art to carry on the centre gripping fixed technology to the cell test tube, have guaranteed the stability of the cell test tube in the cell centrifugation process, and avoid the spring shake to cause the unstable drawback of the cell test tube;

2. through setting up bottom plate, test tube recess, loading board and test tube and leading to the groove etc., be provided with the bottom plate for the lower tip of cell test tube and carry out the bearing, compare in prior art and only set up a loading board, more can increase the stability of cell test tube in centrifugal process, more can avoid cell pollution.

Drawings

FIG. 1 is a schematic structural view of a centrifugal device for cell culture according to the present invention;

FIG. 2 is a top view of the internal structure of a centrifuge for cell culture according to the present invention;

FIG. 3 is an enlarged view of the structure at A in FIG. 2;

fig. 4 is an enlarged schematic view of the structure at B in fig. 2.

In the figure: 1. a base; 2. a support bar; 3. a device barrel; 4. a drive motor; 5. a base plate; 6. a cell tube; 7. carrying a plate; 8. a pull ring; 9. a cover plate; 10. a test tube groove; 11. A test tube through groove; 12. a sliding plate; 13. an arc-shaped fixed splint; 14. an arc-shaped rubber pad; 15. A fixing plate; 16. a threaded post; 17. a knob; 18. a chute; 19. and bending the sliding rod.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments.

In the description of the present invention, it is to be understood that the terms "upper", "lower", "front", "rear", "left", "right", "top", "bottom", "inner", "outer", and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of description and simplicity of description, and do not indicate or imply that the device or element being referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore, should not be construed as limiting the present invention.

Referring to fig. 1-4, a centrifugal device for cell culture, including base 1 and the device barrel 3 of fixing in base 1 upper end through bracing piece 2, the tip fixed mounting has driving motor 4 under the device barrel 3, driving motor 4 output shaft extends to in the device barrel 3 and fixedly connected with bottom plate 5, all be equipped with test tube recess 10 on the bottom plate 5, bottom plate 5 upper end is through a pair of pole setting fixedly connected with loading board 7, all be equipped with the test tube on the loading board 7 and lead to groove 11, the test tube leads to the inslot and puts cell test tube 6, cell test tube 6 bottom is located test tube recess 10, the bilateral symmetry of loading board 7 upper end is provided with a pair of sliding plate 12.

The symmetry all is equipped with the fixed establishment who is used for fixed cell test tube 6 on a pair of sliding plate 12, and fixed establishment includes arc solid fixed splint 13, and arc solid fixed splint 13 all establishes in sliding plate 12 upper end and extends to test tube groove 10 department, and the mutual symmetry of arc solid fixed splint 13 on a pair of sliding plate 12.

The side wall of the sliding plate 12 is provided with a limiting mechanism for limiting the sliding of the sliding plate 12 horizontally, the limiting mechanism comprises sliding grooves 18 and bending sliding rods 19, two groups of sliding grooves 18 are symmetrically arranged at the upper end of the bearing plate 7, one end of each bending sliding rod 19 is fixedly connected to the side wall of the sliding plate 12, and the other end of each bending sliding rod 19 is slidably connected in the corresponding sliding groove 18.

Bearing board 7 upper end bilateral symmetry fixedly connected with a pair of fixed plate 15, install on the fixed plate 15 and be used for driving the gliding actuating mechanism of sliding plate 12, actuating mechanism includes screw thread post 16 and knob 17, screw thread post 16 run through fixed plate 15 and rather than threaded connection, screw thread post 16 inner is connected with sliding plate 12 rotation, knob 17 fixed connection is in screw thread post 16 outer end.

The upper end of the device cylinder 3 is hinged with a cover plate 9, and the side wall of the upper end of the device cylinder 3 is symmetrically and fixedly provided with a pair of pull rings 8.

The arc rubber pad 14 is fixedly arranged on the inner arc surface of the arc fixing splint 13, the anti-skid rubber sleeve is sleeved outside the knob 17, and anti-skid lines are arranged on the surface of the anti-skid rubber sleeve. The former can carry out effective protection to cell test tube 6, and the latter can increase the hand stability when operating personnel operate.

It should be noted that, the automatically controlled and power supply technology of driving motor 4 is ripe prior art, and not the utility model discloses the technical point is located, does not do many here and does not describe repeatedly.

The utility model discloses in, before needing to carry out cell centrifugal operation, open apron 9 earlier, the cell test tube 6 that will be equipped with the cell culture solution passes in the test tube leads to groove 11 and arranges the test tube recess 10 on bottom plate 5 in, rotates a pair of knob 17 afterwards, and knob 17 drives screw post 16 and rotates, promotes a pair of sliding plate 12 and is close to each other under screw post 16 rotates to it is fixed to make two sets of arc solid fixed splint 13 carry out the centre gripping to cell test tube 6.

Close apron 9 and start driving motor 4 afterwards, driving motor 4 drive bottom plate 5 rotates, and then drives loading board 7 and cell test tube 6 rotation to realize cell centrifugation work, the stability of cell test tube 6 has all been well guaranteed to the whole process, can effectively avoid cell test tube 6 to take place to rock in centrifugation process and cause cell pollution.

The above, only be the concrete implementation of the preferred embodiment of the present invention, but the protection scope of the present invention is not limited thereto, and any person skilled in the art is in the technical scope of the present invention, according to the technical solution of the present invention and the utility model, the concept of which is equivalent to replace or change, should be covered within the protection scope of the present invention.

Claims

1. A centrifugal device for cell culture comprises a base (1) and a device cylinder body (3) fixed at the upper end of the base (1) through a support rod (2), and is characterized in that a driving motor (4) is fixedly installed at the lower end of the device cylinder body (3), an output shaft of the driving motor (4) extends into the device cylinder body (3) and is fixedly connected with a bottom plate (5), test tube grooves (10) are formed in the bottom plate (5), a bearing plate (7) is fixedly connected at the upper end of the bottom plate (5) through a pair of vertical rods, test tube through grooves (11) are formed in the bearing plate (7), cell test tubes (6) are placed in the test tube through grooves (11), the bottoms of the cell test tubes (6) are positioned in the test tube grooves (10), a pair of sliding plates (12) are symmetrically arranged on two sides of the upper end of the bearing plate (7), and fixing mechanisms for fixing the cell test tubes (6) are symmetrically arranged on the pair of sliding plates (12), the device is characterized in that a limiting mechanism used for limiting the sliding plate (12) to horizontally slide is installed on the side wall of the sliding plate (12), a pair of fixing plates (15) is symmetrically and fixedly connected to two sides of the upper end of the bearing plate (7), a driving mechanism used for driving the sliding plate (12) to slide is installed on the fixing plates (15), a cover plate (9) is hinged to the upper end of the device cylinder body (3), and a pair of pull rings (8) is symmetrically and fixedly arranged on the side wall of the upper end of the device cylinder body (3).

2. The cell culture centrifuge device according to claim 1, wherein the fixing mechanism comprises arc-shaped fixing splints (13), the arc-shaped fixing splints (13) are all arranged on the upper end of the sliding plate (12) and extend to the test tube groove (10), and the arc-shaped fixing splints (13) on the pair of sliding plates (12) are symmetrical to each other.

3. The cell culture centrifugal device according to claim 1, wherein the limiting mechanism comprises sliding grooves (18) and bending sliding rods (19), two groups of sliding grooves (18) are symmetrically arranged at the upper end of the bearing plate (7), one end of each bending sliding rod (19) is fixedly connected to the side wall of the sliding plate (12), and the other end of each bending sliding rod (19) is slidably connected in the corresponding sliding groove (18).

4. The device of claim 1, wherein the driving mechanism comprises a threaded post (16) and a knob (17), the threaded post (16) penetrates through the fixing plate (15) and is in threaded connection with the fixing plate, the inner end of the threaded post (16) is rotatably connected with the sliding plate (12), and the knob (17) is fixedly connected with the outer end of the threaded post (16).

5. The centrifugal device for cell culture according to claim 2, wherein the arc-shaped fixing splint (13) is fixedly provided with an arc-shaped rubber pad (14) on the inner arc surface.

6. The cell culture centrifugation device as claimed in claim 4, wherein the knob (17) is externally sleeved with an anti-slip rubber sleeve, and the surface of the anti-slip rubber sleeve is provided with anti-slip lines.