CN217288668U

CN217288668U - Biological sample breaker

Info

Publication number: CN217288668U
Application number: CN202220118185.6U
Authority: CN
Inventors: 徐军
Original assignee: Foundmacro Co ltd
Current assignee: Foundmacro Co ltd
Priority date: 2022-01-17
Filing date: 2022-01-17
Publication date: 2022-08-26
Anticipated expiration: 2032-01-17

Abstract

The embodiment of the application discloses biological sample breaker relates to cell breakage and nucleic acid release technical field, including dustcoat and gland, the bottom fixed mounting of dustcoat has evenly distributed's shock attenuation post, the gland is located the top of dustcoat, the top of gland is provided with the ooff lid button, and the top fixed mounting of gland has the handle. This biological sample breaker, cooperation through driving motor and rotating tower and unable adjustment base and unsteady post is used, make this biological sample breaker put into the inside back of dustcoat with the sample tube, the staff can start driving motor, it is rotatory to drive the rotating tower through driving motor and motor shaft, then make unsteady post high-speed rotation, and drive its terminal beating hammering and beat the sample tube, zirconia grinding bead in the cooperation sample tube is broken with the sample, thereby make this biological sample breaker's crushing work high-efficient convenient, and can not destroy the rerum natura parameter of sample.

Description

Biological sample breaker

Technical Field

The application relates to the technical field of cell disruption and nucleic acid release, in particular to a biological sample disruptor.

Background

The cell disruption technique is a technique of releasing the cell contents including the target product components by destroying cell membranes and cell walls by an external force or a chemical method. The method is often used for separating and purifying a certain protein, or extracting DNA, RNA, tissues of different organisms or different parts of the same organism, the cell is difficult to crush, the used method is different, for example, cell membranes of animal organs are fragile and easy to crush, and plants and microorganisms are difficult to crush due to the fact that the cell membranes are firm and consist of cellulose and hemicellulose.

Common crushing methods comprise manual grinding and crushing, are time-consuming and labor-consuming, are easy to topple, inconvenient to use and low in efficiency; ultrasonic crushing, in which electric energy is converted into sound energy through a transducer, the energy is converted into dense small bubbles through a liquid medium, the small bubbles are rapidly burst to generate energy like small bombs, so that the effect of crushing substances such as cells is achieved, but heat is easily accumulated to destroy physical parameters and the like of a sample; the chemical solvent disruption method is easy to destroy the integrity of target products such as nucleic acid, and therefore, a biological sample disruptor is designed to solve the problems.

SUMMERY OF THE UTILITY MODEL

In view of the above, the present application provides a biological sample disruptor to ameliorate the above problems.

In order to achieve the above purpose, the utility model discloses a following technical scheme realizes: the utility model provides a biological sample breaker, includes dustcoat and gland, the bottom fixed mounting of dustcoat has evenly distributed's shock-absorbing column, the gland is located the top of dustcoat, the top of gland is provided with the ooff cover button, and the top fixed mounting of gland has the handle, the inside fixed mounting of dustcoat has the motor fixed disk, the fixed cover in top of motor fixed disk is equipped with driving motor, driving motor's output is provided with the motor shaft, the fixed cover in outside of motor shaft is equipped with the rotating tower, the fixed unable adjustment of outside fixed mounting of rotating tower has evenly distributed's unable adjustment base, unable adjustment base's outside movable sleeve is equipped with the floating column.

Furthermore, a striking hammer is fixedly sleeved at the tail end of the floating column and is made of hard rubber.

Furthermore, the outside of unable adjustment base is provided with the round pin axle that is correlated with the unsteady post, unsteady post adopts the stainless steel to make, and the inside cavity of unsteady post.

Furthermore, the bottom of the fixed base is provided with a swing rod, and the tail end of the swing rod is fixedly sleeved with a counterweight column.

Furthermore, a large-hole disc is fixedly sleeved at the top of the outer cover, and the large-hole disc is matched with the gland.

The application provides a pair of biological sample breaker possesses following beneficial effect:

1. this biological sample breaker, cooperation through driving motor and rotating tower and unable adjustment base and unsteady post is used, make this biological sample breaker put into the inside back of dustcoat with the sample tube, the staff can start driving motor, it is rotatory to drive the rotating tower through driving motor and motor shaft, then make unsteady post high-speed rotation, and drive its terminal beating hammering and beat the sample tube, zirconia grinding bead in the cooperation sample tube is broken with the sample, thereby make the crushing work of this biological sample breaker high-efficient convenient, and can not destroy the rerum natura parameter of sample.

Drawings

In order to more clearly illustrate the technical solutions in the embodiments of the present application, the drawings required to be used in the description of the embodiments are briefly introduced below, and it is obvious that the drawings in the description below are only some embodiments of the present application, and it is obvious for those skilled in the art to obtain other drawings based on these drawings without creative efforts.

Fig. 1 shows a schematic diagram of a biological specimen disruptor according to an embodiment of the present disclosure;

FIG. 2 shows a schematic view of the interior of a housing as proposed by an embodiment of the present application;

FIG. 3 is a schematic diagram of the exterior of a biological specimen disruptor as set forth in embodiments of the present application;

FIG. 4 shows a schematic view of a drive motor and a rotating tower as proposed by an embodiment of the present application;

fig. 5 shows a schematic view of the exterior of a rotating tower as proposed by an embodiment of the present application.

In the figure: 1. a housing; 2. a gland; 3. a switch cover button; 4. a large-hole disc; 5. a shock-absorbing post; 6. a motor fixing disc; 7. a drive motor; 8. a rotating tower; 9. a fixed base; 10. a motor shaft; 11. a floating column; 12. a swing lever; 13. a counterweight column; 14. and (7) a pin shaft.

Detailed Description

The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application, and it is obvious that the described embodiments are only a part of the embodiments of the present application, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present application.

Referring to fig. 1 to 5, the present invention provides a technical solution: a biological sample crusher comprises an outer cover 1 and a gland 2, wherein damping columns 5 which are uniformly distributed are fixedly installed at the bottom of the outer cover 1, the gland 2 is located above the outer cover 1, a switch cover button 3 is arranged at the top of the gland 2, a handle is fixedly installed above the gland 2, a large hole disc 4 is fixedly sleeved at the top of the outer cover 1, when a sample tube is placed inside the outer cover 1, the gland 2 can limit and fix the sample tube through being connected with the large hole disc 4, the large hole disc 4 and the gland 2 are matched with each other, so that the sample tube can be hit by the structure inside the outer cover 1 conveniently, the position of the sample tube in the sample crushing process is ensured, a motor fixing disc 6 is fixedly installed inside the outer cover 1, a driving motor 7 is fixedly sleeved above the motor fixing disc 6, a motor shaft 10 is arranged at the output end of the driving motor 7, a rotating tower 8 is fixedly sleeved outside the motor shaft 10, the external part of the rotating tower 8 is fixedly provided with uniformly distributed fixed bases 9, the driving motor 7 can drive the motor shaft 10 to rotate at a high speed after being started, the motor shaft 10 drives the rotating tower 8 to rotate when rotating, and then the fixed base 9 moves, the external part of the fixed base 9 is movably sleeved with a floating column 11, the tail end of the floating column 11 is fixedly sleeved with a striking hammer, the floating column 11 can drive the striking hammer at the tail end thereof to rotate when rotating, the striking hammer is made of hard rubber, when a sample tube is positioned in the outer cover 1, the striking hammer can strike the sample tube, so that the sample tube vibrates, the sample is crushed by matching with a zirconium oxide grinding bead inside the sample tube, the external part of the fixed base 9 is provided with a pin shaft 14 associated with the floating column 11, the position of the floating column 11 outside the fixed base 9 can deflect, and the pin shaft 14 can limit the position of the floating column 11, avoid floating column 11 to break away from with unable adjustment base 9, floating column 11 adopts the stainless steel to make, and floating column 11's inside cavity, floating column 11 adopts the stainless steel to make the stability of guaranteeing self structure, and reduce manufacturing cost and the holistic weight of structure through self hollow structure, unable adjustment base 9's bottom is provided with swinging arms 12, the terminal fixed cover of swinging arms 12 is equipped with counter weight post 13, in order to guarantee the rotatory effect that rotatory tower 8 drove floating column 11 and unable adjustment base 9, need carry out the counter weight to unable adjustment base 9, consequently, swinging arms 12 and counter weight post 13 have been set up in unable adjustment base 9's below, supplementary floating column 11 and the broken work of hitting the hammer.

In conclusion, the application provides a biological sample breaker, when using, take out the sample pipe, will treat broken sample and zirconia grinding bead and place in the sample pipe, insert the inside of dustcoat 1 with the sample pipe, close gland 2 and carry out spacing fixed to the sample pipe, start driving motor 7, driving motor 7 drives motor shaft 10 high-speed rotatory, it is rotatory to drive rotatory tower 8 when motor shaft 10 is rotatory, make unsteady post 11 high-speed rotation then, deflect under the effect of centrifugal force when unsteady post 11 high-speed rotatory, drive its terminal hitting hammering and beat the sample pipe when unsteady post 11 rotates simultaneously, the zirconia grinding bead that cooperates in the sample pipe is broken the sample, press switch cover button 3 and open gland 2, take out the sample pipe, accomplish the use of whole biological sample breaker can.

In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of description and simplification of description, but do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and thus, should not be construed as limiting the present invention; the terms "first," "second," and "third" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance, and furthermore, unless otherwise explicitly stated or limited, the terms "mounted," "connected," and "connected" are to be construed broadly and may be, for example, fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meaning of the above terms in the present invention can be understood in specific cases to those skilled in the art. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus.

Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims

1. A biological sample breaker, includes dustcoat (1) and gland (2), its characterized in that: the utility model discloses a motor, including dustcoat (1), gland (2), driving shaft, motor fixed disk (6), motor fixed disk (7), the output of driving motor (7) is provided with motor shaft (10), the outside fixed cover of motor shaft (10) is equipped with swivel tower (8), the outside fixed mounting of swivel tower (8) has evenly distributed unable adjustment base (9), the outside movable sleeve of unable adjustment base (9) is equipped with unsteady post (11), gland (2) are located the top of dustcoat (1), the top of gland (2) is provided with bonnet button (3), and the top fixed mounting of gland (2) has the handle, the inside fixed mounting of dustcoat (1) has motor fixed disk (6), the top fixed sleeve of motor fixed disk (6) is equipped with driving motor (7), the output of driving motor (7) is provided with motor shaft (10), the outside fixed sleeve of motor shaft (10) is equipped with swivel tower (8), the outside fixed mounting of swivel tower (8) is equipped with unsteady post (11).

2. A biological specimen disruptor as claimed in claim 1, characterised in that: and the tail end of the floating column (11) is fixedly sleeved with a striking hammer, and the striking hammer is made of hard rubber.

3. A biological specimen disruptor as claimed in claim 1, characterised in that: the fixed base (9) is externally provided with a pin shaft (14) associated with the floating column (11), the floating column (11) is made of stainless steel, and the floating column (11) is hollow.

4. A biological specimen disruptor as claimed in claim 1, characterised in that: the bottom of the fixed base (9) is provided with a swing rod (12), and the tail end of the swing rod (12) is fixedly sleeved with a counterweight column (13).

5. A biological specimen fragmenting instrument as defined in claim 1, wherein: the top of the outer cover (1) is fixedly sleeved with a large-hole disc (4), and the large-hole disc (4) is matched with the gland (2).