CN217093424U

CN217093424U - Dehydration condensation equipment for preparing 4-cyanopyridine-4-carboxylic acid

Info

Publication number: CN217093424U
Application number: CN202220150733.3U
Authority: CN
Inventors: 刘庆贵; 路燕华
Original assignee: Jinan Luohe Pharmaceutical Technology Co ltd
Current assignee: Jinan Luohe Pharmaceutical Technology Co ltd
Priority date: 2022-01-20
Filing date: 2022-01-20
Publication date: 2022-08-02
Anticipated expiration: 2032-01-20

Abstract

The utility model discloses a 4-cyanopyridine-4-carboxylic acid preparation is with dehydration condensation equipment, including a jar body, the outside fixed mounting of the jar body has a ring, and the bottom fixed mounting of a ring has four landing legs, and the top of the jar body is provided with the motor, and the output of motor is provided with the thread plate roller, and the outside fixed mounting of thread plate roller has outer baffle, and the inside of the jar body is provided with semi-permeable board, and semi-permeable board's inside is provided with the solenoid valve, and one side intercommunication at jar body top has the feeder hopper, and the top movable mounting of feeder hopper has the apron. Through the processing case that sets up, because the heating of air current upwards acts on the steam that generates and gets into through the drainage tube and handles incasement portion, catch unreacted clout through reaction clout neutralization board, avoid leaking, then the honeycomb metal otter board carries out the condensation with the steam in the gas through the liquid water of discharging of exhaust gas of two blast pipes, is convenient for increase the feature of environmental protection of device.

Description

Dehydration condensation equipment for preparing 4-cyanopyridine-4-carboxylic acid

Technical Field

The utility model belongs to the technical field of medical intermediate production, concretely relates to 4-cyanopyridine-4-carboxylic acid preparation is with dehydration condensation equipment.

Background

The medical intermediate is actually some chemical raw materials or chemical products used in the process of synthesizing the medicine, the chemical products can be produced in a common chemical plant without the production license of the medicine, and can be used for synthesizing the medicine as long as the medical intermediate reaches some levels, the carboxyl (-COOH) of one amino acid molecule is connected with the amino (-NH2) of another amino acid molecule, and simultaneously, one molecule of water is removed to form a peptide bond (-NH-CO-), the mode is called dehydration condensation reaction, and the chemical products belong to organic chemical reactions.

In the production of medical intermediates, various types of organic chemical products are required, wherein in the preparation of 4-cyanopyridine-4-carboxylic acid, a dehydration condensation mode is adopted in a general preparation process, while in the existing preparation equipment, the reaction efficiency is low, and the reaction is insufficient, so that certain inconvenience is caused in use.

SUMMERY OF THE UTILITY MODEL

Aiming at the defects in the prior art, the utility model aims to provide a dehydration condensation device for preparing 4-cyanopyridine-4-carboxylic acid, which solves the problems of low general reaction efficiency and insufficient reaction in the prior preparation device.

In order to achieve the above object, the utility model provides a following technical scheme: a dehydration and condensation device for preparing 4-cyanopyridine-4-carboxylic acid comprises a tank body, wherein a support ring is fixedly arranged on the outer side of the tank body, four support legs are fixedly arranged at the bottom of the support ring, a motor is arranged at the top of the tank body, a thread plate roller is arranged at the output end of the motor, an outer baffle is fixedly arranged on the outer side of the thread plate roller, a semi-permeable plate is arranged inside the tank body, an electromagnetic valve is arranged inside the semi-permeable plate, a feed hopper is communicated with one side of the top of the tank body, a cover plate is movably arranged at the top of the feed hopper, a heating box is fixedly arranged at the top of the support ring, an air inlet pipe is communicated with the top of the heating box, an air pump is fixedly arranged at the top of the support ring, a treatment box is arranged at the top of the support ring, a plurality of reaction residual material neutralization plates are arranged inside the treatment box, and a honeycomb metal mesh plate is arranged inside the treatment box, the top intercommunication of handling the case has the drainage tube, the bottom and one side of handling the case all communicate there is the discharge pipe, the bottom of the jar body is provided with a plurality of arc pipes, the bleeder vent has been seted up to the inside of arc pipe, the one end intercommunication of arc pipe has the ring canal, the bottom intercommunication of the jar body has the discharging pipe.

Preferably, foot pads are fixedly mounted at the bottoms of the four supporting legs, and reinforcing frames are arranged on the opposite sides of the four supporting legs.

Through adopting above-mentioned technical scheme, the advantage lies in that landing leg and reinforcing frame can make the holistic bearing capacity of jar body increase to the cooperation callus on the sole has increased the stability of standing.

Preferably, the thread plate roller comprises a rotating shaft and thread plates, and the thread plates are uniformly distributed on the outer side of the rotating shaft in a spiral manner.

Through adopting above-mentioned technical scheme, the advantage lies in that the outer baffle of cooperation can stir the even no dead angle of dispersion with material with the laminating of tank wall.

Preferably, the motor is fixedly mounted at the top of the tank body through a support, and the thread plate roller movably penetrates through the top of the tank body through a bearing and extends to the top of the semi-permeable plate.

Through adopting above-mentioned technical scheme, the advantage lies in that the thread plate roller is driven by the motor and rotates to obtain turning moment from this, increased pivoted stability.

Preferably, the input end of the air pump is communicated with the output end of the heating box through a pipeline, and the output end of the air pump is communicated with the inside of the ring pipe through a pipeline.

By adopting the technical scheme, the reactor has the advantage of providing reactants, gaseous catalysts and heat for the interior of the tank body conveniently.

Preferably, one end of the drainage tube, which is far away from the treatment box, is communicated with the top of the tank body, and the honeycomb metal mesh plate is positioned at the bottom of the reaction excess material neutralization plate.

Through adopting above-mentioned technical scheme, the advantage lies in through discharge gas one discharge liquid water of two discharge pipes, is convenient for increase the environmental protection performance of device.

Preferably, the number of the arc-shaped pipes is at least six, and the air permeable plug is arranged inside the air permeable hole.

Through adopting above-mentioned technical scheme, the advantage lies in that setting up of arc pipe is convenient for can evenly get into the inside of jar body with gaseous water conservancy diversion, is convenient for increase the efficiency of evenly applying heat and reactant.

Compared with the prior art, the beneficial effects of the utility model are that:

1. derive the air current through setting up arc pipe and bleeder vent, can pass through the atomizing through half permeable plate, vaporization liquid drop and air current, and can't pass through the solid particle material of reaction, then catalyst and the neutralization material entering and raw materials mixing dispersion with the reaction are even, carry out the dehydration condensation, and open the solenoid valve after finishing, the motor reversal passes through the solenoid valve with the solid powder particle material after the reaction and drops jar body bottom, and discharge through the discharging pipe, reaction rate can be increased effectively to this scheme, and the operating speed has been promoted, excellent in use effect.

2. Through the processing case that sets up, because the heating of air current upwards acts on the steam that generates and gets into through the drainage tube and handles incasement portion, catch unreacted clout through reaction clout neutralization board, avoid leaking, then the honeycomb metal otter board carries out the condensation with the steam in the gas through the liquid water of discharging of exhaust gas of two blast pipes, is convenient for increase the feature of environmental protection of device.

Drawings

FIG. 1 is a schematic view of a front perspective structure of the present invention;

fig. 2 is a schematic view of a rear-view three-dimensional appearance structure of the present invention;

FIG. 3 is a front sectional view of the present invention;

FIG. 4 is a schematic view of the internal structure of the treatment tank of the present invention;

in the figure: 1. a tank body; 2. a branch ring; 3. a support leg; 4. a honeycomb metal mesh plate; 5. an air pump; 6. a heating box; 7. an air inlet pipe; 8. a feed hopper; 9. a cover plate; 10. a motor; 11. a drainage tube; 12. a treatment tank; 13. a discharge pipe; 14. a thread plate roller; 15. an outer baffle; 16. air holes are formed; 17. a ring pipe; 18. a discharge pipe; 19. an arc tube; 20. a semi-permeable plate; 21. neutralizing the reaction residual material with a plate; 22. an electromagnetic valve.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is to be understood that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work all belong to the protection scope of the present invention.

As shown in figures 1-4, a dehydration and condensation device for preparing 4-cyanopyridine-4-carboxylic acid comprises a tank body 1, a support ring 2 is fixedly arranged on the outer side of the tank body 1, four support legs 3 are fixedly arranged at the bottom of the support ring 2, a motor 10 is arranged at the top of the tank body 1, a thread plate roller 14 is arranged at the output end of the motor 10, an outer baffle 15 is fixedly arranged on the outer side of the thread plate roller 14, a semi-permeable plate 20 is arranged in the tank body 1, an electromagnetic valve 22 is arranged in the semi-permeable plate 20, a feed hopper 8 is communicated with one side of the top of the tank body 1, a cover plate 9 is movably arranged at the top of the feed hopper 8, a heating box 6 is fixedly arranged at the top of the support ring 2, an air inlet pipe 7 is communicated with the top of the heating box 6, an air pump 5 is fixedly arranged at the top of the support ring 2, a treatment box 12 is arranged at the top of the support ring 2, a plurality of reaction remainder neutralization plates 21 are arranged in the treatment box 12, the inside of handling case 12 is provided with honeycomb metal mesh plate 4, and the top intercommunication of handling case 12 has drainage tube 11, and the bottom and one side of handling case 12 all communicate there is discharge pipe 13, and the bottom of jar body 1 is provided with a plurality of arc pipes 19, and bleeder vent 16 has been seted up to the inside of arc pipe 19, and the one end intercommunication of arc pipe 19 has ring pipe 17, and the bottom intercommunication of jar body 1 has discharging pipe 18.

The working principle of the technical scheme is as follows:

during operation, an operator firstly communicates an air inlet pipe 7 with an air supply device, the device is similar to atomizing reaction catalysts, required solution and gas for reaction and condensation, then the gas is heated to reaction temperature by a heating box 6 and then is introduced into the tank body 1 through an air pump 5, at the moment, the operator opens a cover plate 9 and adds reactants into the tank body 1 through a feed hopper 8, then closes the cover plate 9, then starts the motor 10 to rotate, the motor 10 rotates to drive a thread plate roller 14 to rotate, the materials can be uniformly stirred and dispersed without dead angles by matching with an outer baffle 15 and the wall of the tank body 1, wherein the output end of the air pump 5 pumps air flow into a ring pipe 17 through a pipeline, the air flow is guided out through an arc pipe 19 and an air vent 16, and solid granular materials which cannot pass through the reaction can be atomized, vaporized liquid drops and the air flow through a semi-permeable plate 20, then catalyst and the neutralization material entering of reaction and raw materials mixing dispersion are even, carry out the dehydration condensation, because the heating of air current upwards acts on the steam that generates and gets into through drainage tube 11 and handle inside the case 12, be convenient for increase the environmental protection performance of device, and open solenoid valve 22 after the end, the solid powder granule material after the motor 10 reversal will react passes through solenoid valve 22 and drops jar body 1 bottom, and discharge through discharging pipe 18, this scheme can increase reaction rate effectively, and the operating speed has been promoted, excellent in use effect.

In another embodiment, as shown in fig. 1 to 3, a foot pad is fixedly installed at the bottom of each of the four legs 3, and reinforcing frames are provided at opposite sides of the four legs 3.

The supporting legs 3 and the reinforcing frame can increase the whole bearing capacity of the tank body 1 and increase the standing stability by matching with a foot pad.

In another embodiment, as shown in FIG. 3, the flighted plate roll 14 comprises a rotating shaft and a flighted plate uniformly distributed in a spiral on the outside of the rotating shaft.

Screw plate roller 14 is when rotating, and the screw action of the screw plate in screw plate roller 14 outside can be with the material upwards disturbance, is similar to fan disturbance air current, then because screw plate roller 14 is the screw spiral and distributes and there is the fracture in the centre, therefore the material of stirring equally receives the effect of gravity to in the spiral upwards, interact between turning force and gravity, cooperation outer baffle 15 can be with the laminating of jar body 1 wall with the even no dead angle of material stirring dispersion.

In another embodiment, as shown in fig. 3, the motor 10 is fixedly mounted on the top of the tank 1 by a bracket, and the thread plate roller 14 is movably mounted through the top of the tank 1 by a bearing and extends to the top of the semi-permeable plate 20.

The motor 10 obtains a rotation moment through the bracket, the thread plate roller 14 is driven by the motor 10 to rotate, and thus the rotation moment is obtained, and the rotation stability is improved.

In another embodiment, as shown in fig. 1-3, the input of the air pump 5 is connected to the output of the heating chamber 6 via a pipe, and the output of the air pump 5 is connected to the interior of the loop 17 via a pipe.

The output end of the air pump 5 pumps the air flow into the annular pipe 17 through a pipeline, and the air flow is guided out through the arc-shaped pipe 19 and the air holes 16, so that reactants, gaseous catalysts and heat can be provided for the inside of the tank body 1 conveniently.

In another embodiment, as shown in FIGS. 1 to 3, the end of the draft tube 11 remote from the treatment tank 12 communicates with the top of the vessel body 1, and the mesh sheet 4 of the honeycomb metal is located in the reaction residue and at the bottom of the plate 21.

Because the steam that the heating of air current upwards acted on the formation gets into through drainage tube 11 inside handling case 12, catches unreacted clout through reaction clout neutralization board 21, avoids leaking, and then honeycomb metal mesh plate 4 condenses the steam in the gas and discharges liquid water through discharge gas of two discharge pipes 13, is convenient for increase the feature of environmental protection of device.

In another embodiment, as shown in fig. 3, the number of the arc-shaped tubes 19 is at least six, and the gas permeation plugs are provided inside the gas permeation holes 16.

The setting up of arc pipe 19 is convenient for can be evenly get into jar body 1's inside with gaseous water conservancy diversion, is convenient for increase the efficiency of evenly applying heat and reactant to the effect of gas permeation stopper is avoided solid powder granule to get into bleeder vent 16 and is blockked up when arranging the material, has increased the operation convenience.

The utility model discloses a theory of operation and use flow: during operation, an operator firstly communicates an air inlet pipe 7 with an air supply device, the device is similar to atomizing reaction catalyst, required solution and gas for reaction and condensation, then the gas is heated to reaction temperature by a heating box 6 and then is introduced into the tank body 1 by an air pump 5, at the moment, the operator opens a cover plate 9 and adds reactants into the tank body 1 by a feed hopper 8, then closes the cover plate 9, then starts the motor 10 to rotate, the motor 10 rotates to drive a thread plate roller 14 to rotate, when the thread plate roller 14 rotates, the spiral action of the thread plate roller 14 can disturb the materials upwards, the air flow is disturbed similarly to a fan, and then the stirred materials are stirred and dispersed uniformly without dead angles by the aid of the spiral distribution of the thread plate roller 14 and the fracture in the middle, wherein the output end of the air pump 5 pumps the air flow into the circular pipe 17 through the pipeline, and guides the air flow out through the arc-shaped pipe 19 and the air holes 16, the semi-permeable plate 20 can atomize, vaporize liquid drops and air flow, and can not pass through the reacted solid particle material, then the reacted catalyst and the neutralized material enter and are uniformly mixed and dispersed with the raw material, dehydration condensation is carried out, the water vapor generated by the heating of the air flow upwards acts through the drainage pipe 11 and enters the inside of the processing box 12, the unreacted remainder is captured through the reaction remainder neutralizing plate 21, the leakage is avoided, then the honeycomb metal mesh plate 4 condenses the water vapor in the gas and discharges liquid water through two discharge pipes 13, the environment-friendly performance of the device is increased, the electromagnetic valve 22 is opened after the completion, the motor 10 rotates reversely, and the reacted solid powder particle material falls to the bottom of the tank body 1 through the electromagnetic valve 22, and the reaction liquid is discharged through the discharge pipe 18, so that the reaction rate can be effectively increased, the operation speed is increased, and the using effect is good.

Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims

1. A dehydration condensation equipment for preparing 4-cyanopyridine-4-carboxylic acid comprises a tank body (1), and is characterized in that: the outer side of the tank body (1) is fixedly provided with a supporting ring (2), the bottom of the supporting ring (2) is fixedly provided with four supporting legs (3), the top of the tank body (1) is provided with a motor (10), the output end of the motor (10) is provided with a thread plate roller (14), the outer side of the thread plate roller (14) is fixedly provided with an outer baffle (15), the inside of the tank body (1) is provided with a semi-permeable plate (20), the inside of the semi-permeable plate (20) is provided with an electromagnetic valve (22), one side of the top of the tank body (1) is communicated with a feeding hopper (8), the top of the feeding hopper (8) is movably provided with a cover plate (9), the top of the supporting ring (2) is fixedly provided with a heating box (6), the top of the heating box (6) is communicated with an air inlet pipe (7), the top of the supporting ring (2) is fixedly provided with an air pump (5), the top of the supporting ring (2) is provided with a treatment box (12), the inside of the treatment box (12) is provided with a plurality of reaction excess material neutralizing plates (21), the inside of the treatment box (12) is provided with a honeycomb metal mesh plate (4), the top of the treatment box (12) is communicated with a drainage tube (11), the bottom and one side of the treatment box (12) are communicated with a discharge tube (13), the bottom of the tank body (1) is provided with a plurality of arc-shaped tubes (19), air holes (16) are formed in the inner parts of the arc-shaped tubes (19), one ends of the arc-shaped tubes (19) are communicated with an annular tube (17), and the bottom of the tank body (1) is communicated with a discharge tube (18).

2. The dehydration condensation apparatus for the production of 4-cyanopyridine-4-carboxylic acid according to claim 1, wherein: foot pads are fixedly mounted at the bottoms of the four supporting legs (3), and reinforcing frames are arranged on the opposite sides of the four supporting legs (3).

3. The dehydration condensation apparatus for the production of 4-cyanopyridine-4-carboxylic acid according to claim 1, wherein: the thread plate roller (14) comprises a rotating shaft and thread plates, and the thread plates are uniformly distributed on the outer side of the rotating shaft in a spiral mode.

4. The dehydration condensation apparatus for the production of 4-cyanopyridine-4-carboxylic acid according to claim 1, wherein: the motor (10) is fixedly arranged at the top of the tank body (1) through a support, and the thread plate roller (14) movably penetrates through the top of the tank body (1) through a bearing and extends to the top of the semi-permeable plate (20).

5. The dehydration condensation apparatus for the production of 4-cyanopyridine-4-carboxylic acid according to claim 1, wherein: the input end of the air pump (5) is communicated with the output end of the heating box (6) through a pipeline, and the output end of the air pump (5) is communicated with the inside of the ring pipe (17) through a pipeline.

6. The dehydration condensation apparatus for the production of 4-cyanopyridine-4-carboxylic acid according to claim 1, wherein: one end of the drainage tube (11) far away from the treatment box (12) is communicated with the top of the tank body (1), and the honeycomb metal mesh plate (4) is positioned at the bottom of the reaction residual material neutralization plate (21).

7. The dehydration condensation apparatus for the production of 4-cyanopyridine-4-carboxylic acid according to claim 1, wherein: the number of the arc-shaped pipes (19) is at least six, and the air permeable plugs are arranged in the air permeable holes (16).