CN217068916U

CN217068916U - Tenon type reagent clamping plate

Info

Publication number: CN217068916U
Application number: CN202220387870.9U
Authority: CN
Inventors: 庄佳霖
Original assignee: Chuangmao Biotechnology Co ltd
Current assignee: Chuangmao Biotechnology Co ltd
Priority date: 2022-02-25
Filing date: 2022-02-25
Publication date: 2022-07-29
Anticipated expiration: 2032-02-25

Abstract

A tenon type reagent card chuck comprises six clamping clips, six elastic clamping tenons and a plurality of easy-to-disassemble breakpoints; wherein, a plurality of reagent filling grooves are arranged on the clamp and used for filling the biological sample extraction reagent, and the reagent filling grooves are tapered grooves with wide upper parts and narrow lower parts; the elastic tenon is buckled at one end of the clamping clip; and the easy-to-detach breakpoints are arranged between the two adjacent clips, so that the two adjacent clips are mutually connected. Borrow this, this creation tenon formula reagent card clamping disc is used for filling the required chemical reagent of biological physical examination body extraction in-process to can match automatic biological physical examination body extraction appearance and use, and the setting of easy breaking point can be based on the experiment quantity demand and cut and get required reagent and fill the groove.

Description

Tenon type reagent clamping plate

Technical Field

The utility model relates to a clamping tenon type reagent clamping plate for loading chemical reagents required in the biological sample extraction process and further matching an automatic biological sample extraction instrument.

Background

As biotechnology is rapidly developed and applied, the demand for biochemical and molecular biological methods for detection is increasing. In the case of nucleic acid (DNA or RNA) technology, nucleic acid extraction is the first step in the experimental procedures of life science and academic research, and is also an essential link in the process of molecular diagnosis. The polymerase chain reaction instrument which can simultaneously amplify and analyze nucleic acid is available in the market nowadays, and can complete all detection steps by matching with an electric liquid-moving machine, a nucleic acid hybridization reactor, a cleaning instrument, a signal interpretation instrument and the like. However, the reagent filling tank can only be used with a single reagent, and the problems to be overcome in the art are the number of samples, the amount of reagent in the reagent filling tank, and the preparation time.

In order to overcome the disadvantages and problems of the above-mentioned reagent cartridge, and to improve the convenience of the user in using the reagent cartridge, the present inventors have been dedicated to research and develop the solution thereof to serve the public and promote the development of the industry, and have the creation of the present invention through many time-consuming ideas.

SUMMERY OF THE UTILITY MODEL

The main object of the utility model is to provide a supply automatic biological property to examine card tenon formula reagent card (holding) chuck that physical property extraction appearance was used, in the biological property is examined the body extraction in-process, each is examined the body extraction and can be used multiple and a small amount of chemical reagent, and this creation can be packed the extraction reagent in advance in the reagent clamping, deuterogamies the liquid-moving system completion extraction of automatic biological property physical property extraction appearance. Secondly, the reagent filling tank of the creation can be used for simultaneously carrying ten different reagents and matching with an automatic biological sample extraction instrument for production; and the elastic tenon of the present creation can effectively fix the clip on the extraction instrument to match with a large number of sample loading. Moreover, the six-card clamp design of this creation can save the time of prepareeing material in a large number, if meet odd number of specimens, can use easy breaking point to select required reagent quantity in addition.

In order to achieve the above purpose, the utility model adopts the technical scheme that: a mortise and tenon type reagent chuck, comprising: the reagent extraction device comprises six clamps, wherein each clamp is provided with a plurality of reagent filling grooves, the reagent filling grooves are used for filling a biological sample extraction reagent, and each reagent filling groove is a conical groove with a wide upper part and a narrow lower part; the six elastic clamping tenons are buckled at one end of the clamping clip; the plurality of easy-to-detach breakpoints are arranged between the two adjacent clips, so that the two adjacent clips are mutually connected; wherein, these reagent filling grooves include a first reagent filling groove and several second reagent filling grooves.

In the tenon type reagent card chuck of the present invention, a notch is formed at one end of the card holder, two ends of the notch are respectively recessed to form a concave part, and a convex clip column corresponding to the concave part is arranged at the bottom end of the elastic tenon.

In the tenon type reagent chuck plate of the present invention, two sides of the bottom of the first reagent filling groove are respectively provided with a groove.

In the tenon type reagent chuck plate of the present invention, the reagent filling groove has a depth D from the open end to the tapered bottom, the depth D is 25.00-25.80 mm, and the length D of the open end of the reagent filling groove is 14.50-15.00 mm.

In the tenon type reagent card chuck of the present invention, the length L of the clip is 103.24-109.4 mm, and the six clips are connected to each other by the easily detachable breaking points to form a width W, which is 103.69-109.6 mm.

In the tenon type reagent card chuck of the aforesaid creation, link through these easy breaking points between two adjacent clamps, and borrow an external force to separate two adjacent clamps through these easy breaking points.

In the tenon type reagent chuck of the present invention, the first reagent filling groove is used to fill 50 μ l to 1.2mL of reagent, and the second reagent filling groove is used to fill 50 μ l to 2.0mL of reagent.

In view of the above advantages, and to further enable the examiner to understand the present disclosure, a preferred embodiment is disclosed as follows, which is described in detail with reference to the drawings and the accompanying drawings.

Drawings

FIG. 1 is a perspective view of a tenon type reagent cartridge according to an embodiment of the present invention;

FIG. 2 is a perspective view of another view (bottom) of a tenon type reagent cartridge according to an embodiment of the present invention;

FIG. 3 is a top view of a mortise and tenon type reagent chuck plate according to an embodiment of the present invention;

fig. 4 is a sectional view taken along line a-a of fig. 3.

Description of the symbols:

1 tenon type reagent clamping plate

10 card clip

101 notch

102 card concave part

20 elastic tenon

201 convex column

30 easy-to-dismount-break point

40 reagent filling tank

40a first reagent-filled tank

40b second reagent-filled tank

401 open end

50 grooves.

Detailed Description

The following embodiments are provided to illustrate the present disclosure, and those skilled in the art will readily appreciate other advantages and capabilities from the present disclosure. Moreover, the present disclosure may be practiced or applied to other embodiments, and various modifications and changes may be made without departing from the spirit thereof.

Referring to fig. 1, the present invention relates to a tenon type reagent chuck, the tenon type reagent chuck 1 includes: six clips 10, six elastic tenons 20 and a plurality of easy-to-detach points 30. Wherein: the card holder 10 is provided with a plurality of reagent filling grooves 40, the reagent filling grooves 40 are used for filling biological sample extraction reagents, the reagent filling grooves 40 are tapered grooves with wide upper parts and narrow lower parts, the tapered grooves are in asymmetric eccentric design (please refer to fig. 2 and 4), in addition, one end of the card holder 10 is provided with a notch 101, and two ends of the notch 101 are respectively recessed to form a card recess 102. The bottom end of the elastic tenon 20 is provided with a convex clamping column 201, and the elastic tenon 20 can be clamped at one end of the clamp 10 (see fig. 1) through the buckling of the convex clamping column 201 and the concave clamping part 102; when the tenon type reagent card chuck 1 is placed in an automatic biological physical property extraction instrument, the clamping clip 10 is fixed and is not easy to shake by virtue of the buckle between the elastic tenon 20 and the clamping clip 10, the clamping convex column 201 of the elastic tenon 20 can be pressed after the use is finished, the clamping clip 10 is convenient to take out by virtue of the elasticity of the elastic tenon 20, and therefore the tenon type reagent card chuck 1 can be quickly and effectively fixed or separated in an extraction mechanism by virtue of the elastic tenon 20. The easily detachable points 30 are disposed between two adjacent clips 10, and the two adjacent clips 10 are connected to each other by the easily detachable points 30 (see fig. 3). The reagent filling tank 40 includes a first reagent filling tank 40a and a plurality of second reagent filling tanks 40b, please refer to fig. 2, wherein two sides of the bottom of the first reagent filling tank 40a are respectively provided with a groove 50, so that the reagent filling amount of the first reagent filling tank 40a is 50 μ l-1.2 mL, and the second reagent filling tank 40b is used for filling 50 μ l-2.0 mL of reagent. The design of the grooves 50 can effectively cooperate with a liquid transfer system of the extraction instrument to absorb reagents with small volume, and can effectively reduce the situation that liquid remains when a micropipette of the liquid transfer system absorbs the reagents. As shown in FIG. 3, the six clips 10 have a length L of 103.24-109.4 mm, and the six clips 10 are connected to each other through the easy breaking points 30 to form a width W, which is 103.69-109.6 mm. Two adjacent clamping 10 are connected through a plurality of easy-to-detach points 30, and the two adjacent clamping 10 are easily separated through the easy-to-detach points 30.

As shown in FIG. 4, the opening end 401 of the reagent filling groove 40 has a depth D from the bottom of the tapered groove, the depth D is 25.00-25.80 mm, and the length D of the opening end of the reagent filling groove 40 is 14.5-15.00 mm. In the biological sample purification reagent, the formulation can use a small volume of reagent, and at this time, the first reagent filling tank 40a of the present invention can be used, and the groove structure at the bottom of the first reagent filling tank 40a can effectively cooperate with the liquid transfer system of the extraction apparatus to suck a small volume of reagent. And the conical bottoms of all the slot positions are in an asymmetric eccentric design, so that the vacuum burst situation of a pipette of a pipetting system during suction can be avoided.

The reagent extracted from the biological sample is placed in the appropriate reagent filling grooves 40 according to different formula conditions, and can be stored for later use after being sealed by an aluminum film. After confirming the number of samples, the present creation of the clip 10 can be adapted to the rapid stock preparation of a large number of samples, and if there are odd numbers of samples, the easy breaking point 30 can be used to select the appropriate amount of reagent. After confirming the sample loading quantity, the automatic extraction instrument can be installed on the sample and the reagent clamp, and the elastic clamping tenon 20 can enable the clamping clamp 10 to be quickly and accurately fixed on the automatic extraction instrument.

The above-mentioned embodiments are merely exemplary for convenience of description, and the claimed subject matter should not be limited to the above-mentioned embodiments, but should be defined only in accordance with the appended claims.

Claims

1. A mortise and tenon type reagent chuck, comprising:

the reagent extraction device comprises six clamps, wherein each clamp is provided with a plurality of reagent filling grooves, the reagent filling grooves are used for filling a biological sample extraction reagent, and each reagent filling groove is a conical groove with a wide upper part and a narrow lower part;

the six elastic clamping tenons are buckled at one end of the clamping clip;

and

the plurality of easy-to-detach breakpoints are arranged between the two adjacent clips, so that the two adjacent clips are mutually connected;

wherein, these reagent filling grooves include a first reagent filling groove and several second reagent filling grooves.

2. The mortise and tenon type reagent card chuck of claim 1, wherein one end of the card holder is provided with a recess, both ends of the recess are respectively recessed to form a card recess, and the bottom end of the elastic mortise and tenon is provided with a card convex column corresponding to the card recess.

3. The mortise and tenon type reagent card chuck of claim 1, wherein the first reagent filling slot is formed with a groove at both sides of a bottom thereof.

4. The mortise and tenon type reagent card chuck of claim 1, wherein the open end of the reagent filling slot to the tapered bottom has a depth D of 25.00 to 25.80 mm, and the length D of the open end of the reagent filling slot is 14.50 to 15.00 mm.

5. The mortise and tenon type reagent card chuck of claim 1, wherein the length L of the clips is 103.24-109.4 mm, and the clips are connected to each other by the frangible points to form a width W of 103.69-109.6 mm.

6. The mortise and tenon type reagent card chuck of claim 1, wherein the first reagent filling slot is configured to be filled with 50 μ l to 1.2mL of reagent.

7. The mortise and tenon type reagent card chuck of claim 1, wherein the second reagent filling slot is configured to be filled with 50 μ l to 2.0mL of reagent.