TWM628745U - Non-tenon type regent clamp tray - Google Patents

Non-tenon type regent clamp tray Download PDF

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Publication number
TWM628745U
TWM628745U TW111201950U TW111201950U TWM628745U TW M628745 U TWM628745 U TW M628745U TW 111201950 U TW111201950 U TW 111201950U TW 111201950 U TW111201950 U TW 111201950U TW M628745 U TWM628745 U TW M628745U
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Taiwan
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reagent
tenon
clips
type
groove
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TW111201950U
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Chinese (zh)
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莊佳霖
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創茂生技股份有限公司
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Priority to TW111201950U priority Critical patent/TWM628745U/en
Publication of TWM628745U publication Critical patent/TWM628745U/en

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Abstract

本新型係關於一種非卡榫式試劑卡夾盤,包括六個卡夾及複數個易拆斷點;每一卡夾上穿設十個試劑充填槽,每一試劑充填槽用以填充生物性檢體萃取試劑,該每一試劑充填槽的底部係為一錐型槽;該些易拆斷點設置於相鄰兩卡夾之間,使相鄰的兩卡夾相互連接。藉此,本創作非卡榫式試劑卡夾盤用於填裝生物性檢體萃取過程中所需的化學試劑,並可搭配自動化生物性檢體萃取儀使用,且易拆斷點的設置可依實驗用量需求而剪取所需的試劑充填槽。The new model relates to a non-tenon-type reagent cartridge, which includes six clips and a plurality of easily dismantled points; ten reagent filling grooves are perforated on each clip, and each reagent filling groove is used for filling biological The sample extracts reagents, the bottom of each reagent filling groove is a conical groove; the easy-to-break points are set between two adjacent clips to connect the two adjacent clips to each other. Therefore, the non-tenon-type reagent cartridge of the present invention is used to fill the chemical reagents required in the biological sample extraction process, and can be used with an automatic biological sample extraction instrument, and the setting of the easy-to-break point can be Cut the required reagent filling tank according to the experimental demand.

Description

非卡榫式試劑卡夾盤Non-tenon reagent cartridge chuck

本創作係關於一種填裝生物性檢體萃取過程中所需的化學試劑,進而搭配自動化生物性檢體萃取儀使用之自動化生物性檢體萃取儀用之非卡榫式試劑卡夾盤。This creation is about a non-tenon-type reagent cartridge for filling the chemical reagents required in the extraction process of biological specimens, and then collocating with the automated biological specimen extraction apparatus.

隨著生物科技快速地發展並應用,生化及分子生物方法進行檢測的需求日漸增加。就核酸(DNA或RNA)技術而言,核酸萃取技術是生命科學與學術研究實驗流程的第一步,亦是進行分子診斷過程中必不可少的環節。現今市面上具有可同時進行核酸放大及分析之聚合酶連鎖反應儀,並同時搭配電動移液機、核酸雜交反應器、清洗儀、訊號判讀儀等,以完成所有的檢測步驟。然而,在使用上試劑填裝槽僅能配搭單一試劑使用,且檢體數目與試劑填裝槽的使用量不同及備料時間都是該技術領域所要克服的問題。With the rapid development and application of biotechnology, the demand for biochemical and molecular biological methods for detection is increasing day by day. As far as nucleic acid (DNA or RNA) technology is concerned, nucleic acid extraction technology is the first step in the experimental process of life science and academic research, and it is also an indispensable link in the process of molecular diagnosis. Today, there are polymerase chain reaction instruments on the market that can perform nucleic acid amplification and analysis at the same time, and are equipped with electric pipettes, nucleic acid hybridization reactors, cleaning instruments, signal interpretation instruments, etc. to complete all detection steps. However, in use, the reagent filling tank can only be used with a single reagent, and the number of specimens, the usage amount of the reagent filling tank, and the preparation time are all problems to be overcome in this technical field.

為克服上述試劑卡夾盤的使用缺點及問題,以提升使用者使用試劑卡夾盤之便利性,本案創作人致力於研發其解決方案,以服務社會大眾及促進此業之發展,遂經多時之構思而有本發明之產生。In order to overcome the above-mentioned shortcomings and problems in the use of the reagent cartridge chuck, and to improve the convenience for users to use the reagent cartridge chuck, the creator of this case is committed to developing its solutions to serve the public and promote the development of this industry. The idea of the time led to the invention of the present invention.

本創作之主要目的係在提供一種自動化生物性檢體萃取儀用之非卡榫式試劑卡夾盤,在生物性檢體萃取過程中,每一個檢體萃取會用到多項且少量的化學試劑,本創作可將萃取試劑預封填在試劑卡夾中,再配合自動化生物性檢體萃取儀的移液系統完成萃取。其次,本創作的六個卡夾設計可大量節省備料時間,另外若遇到畸零數的檢體,可使用易拆斷點選擇所需要的試劑數量,將試劑有效使用。The main purpose of this creation is to provide a non-tenon-type reagent cartridge for an automatic biological sample extraction instrument. During the biological sample extraction process, each sample extraction will use multiple and small amounts of chemical reagents , This creation can pre-fill the extraction reagent in the reagent cartridge, and then cooperate with the pipetting system of the automatic biological sample extraction instrument to complete the extraction. Secondly, the design of the six clips in this creation can save a lot of time for material preparation. In addition, if you encounter an abnormal number of specimens, you can use the easy breaking point to select the required number of reagents and use the reagents effectively.

為達上述目的,本發明係提供一種非卡榫式試劑卡夾盤包括:六個卡夾及複數個易拆斷點;其中,每一卡夾上穿設十個試劑充填槽,每一試劑充填槽用以填充生物性檢體萃取試劑,該每一試劑充填槽的底部係為一上寬下窄的錐型槽。其次,該些易拆斷點設置於相鄰兩卡夾之間,使相鄰的兩卡夾相互連接。In order to achieve the above-mentioned purpose, the present invention provides a non-tenon-type reagent cartridge chuck comprising: six clips and a plurality of easily dismantled points; wherein, ten reagent filling grooves are drilled on each clip, and each reagent The filling grooves are used for filling biological sample extraction reagents, and the bottom of each reagent filling groove is a conical groove that is wide at the top and narrow at the bottom. Secondly, the easily detachable points are arranged between two adjacent clips, so that the two adjacent clips are connected to each other.

於前述本創作之非卡榫式試劑卡夾盤中,該每一試劑充填槽的一開口端至該錐型槽的底部具有一深度D,該深度D係為31.30~31.90毫米。In the aforementioned non-tenon-type reagent cartridge of the present invention, an open end of each reagent filling groove has a depth D to the bottom of the tapered groove, and the depth D is 31.30-31.90 mm.

於前述本創作之非卡榫式試劑卡夾盤中,該些試劑充填槽包括複數個第一試劑充填槽及複數個第二試劑充填槽。In the aforementioned non-tenon-type reagent cartridge of the present invention, the reagent filling grooves include a plurality of first reagent filling grooves and a plurality of second reagent filling grooves.

於前述本創作之非卡榫式試劑卡夾盤中,該些第一試劑充填槽用以填充50μl~1.2mL的試劑。In the aforementioned non-tenon-type reagent cartridge of the present invention, the first reagent filling grooves are used to fill 50 μl-1.2 mL of reagents.

於前述本創作之非卡榫式試劑卡夾盤中,該第二試劑充填槽用以填充50μl~2.0mL的試劑。In the aforementioned non-tenon-type reagent cartridge of the present invention, the second reagent filling groove is used to fill 50 μl-2.0 mL of reagent.

於前述本創作之非卡榫式試劑卡夾盤中,該六個卡夾的長度L係為100.93~101.53毫米,且透過該些易拆斷點將該六個卡夾相互連接以形成一寬度W,該寬度W係為105.98~106.58毫米。In the aforementioned non-tenon-type reagent cartridge of the present invention, the length L of the six clips is 100.93-101.53 mm, and the six clips are connected to each other through the easy breaking points to form a width W , the width W is 105.98~106.58 mm.

於前述本創作之非卡榫式試劑卡夾盤中,相鄰兩卡夾之間透過五個該些易拆斷點連結。In the aforementioned non-tenon-type reagent cartridge of the present invention, two adjacent cartridges are connected through five of these easily detachable points.

於前述本創作之非卡榫式試劑卡夾盤中,透過五個該些易拆斷點並藉由一外力將相鄰兩卡夾分離。In the aforementioned non-tenon-type reagent cartridge of the present invention, two adjacent cartridges are separated by an external force through the five easy-to-break points.

根據上述諸多優點,並為使審查委員對本創作能進一步的瞭解,故揭露一較佳之實施方式如下,配合圖式、圖號,將本創作之構成內容及其所達成的功效詳細說明如後。Based on the above-mentioned advantages, and in order to enable the reviewers to have a better understanding of the creation, a preferred implementation is disclosed as follows. The composition of the creation and its effects are described in detail below in conjunction with the drawings and drawing numbers.

以下係藉由具體實施例說明本創作之實施方式,熟習此技藝之人士可由本說明書所揭示之內容輕易地了解本創作之其他優點與功效。此外,本創作亦可藉由其他不同具體實施例加以施行或應用,在不悖離本創作之精神下進行各種修飾與變更。The following describes the implementation of the present creation by means of specific examples, and those skilled in the art can easily understand other advantages and effects of the present creation from the contents disclosed in this specification. In addition, the present creation can also be implemented or applied by other different specific embodiments, and various modifications and changes can be made without departing from the spirit of the present creation.

請參照圖1至3,圖1為本新型實施例非卡榫式試劑卡夾盤之立體示意圖;圖2為本新型實施例非卡榫式試劑卡夾盤之底部立體示意圖;以及圖3為本新型實施例非卡榫式試劑卡夾盤之仰視圖。Please refer to FIGS. 1 to 3. FIG. 1 is a schematic perspective view of a non-tenon-type reagent cartridge chuck according to a novel embodiment; FIG. 2 is a bottom perspective view of a non-tenon-type reagent cartridge chuck according to the novel embodiment; Bottom view of the non-tenon-type reagent cartridge chuck of the novel embodiment.

如圖1至圖2所示,本創作係關於一種非卡榫式試劑卡夾盤1包括六個卡夾10及複數個易拆斷點20;其中,每一卡夾10上穿設十個試劑充填槽11,每一試劑充填槽11用以填充生物性檢體萃取試劑,該每一試劑充填槽11的底部係為一上寬下窄的錐型槽12。其次,該些易拆斷點20設置於相鄰兩卡夾10之間,使相鄰的兩卡夾10相互連接。將生物性樣本萃取的試劑,依不同配方的狀況放置在本創作適當的該試劑充填槽11,經鋁膜封膜後便可儲存備用。再確認樣本數後,本創作的六個卡夾10可因應大量上樣的快速備料,若樣本有畸零數則可使用該易拆斷點20來選則適當的試劑用量。確認上樣數量後,便可將樣本跟試劑夾安裝上自動化萃取儀。As shown in FIG. 1 to FIG. 2 , the present invention relates to a non-tenon-type reagent cartridge 1 including six clips 10 and a plurality of easy-to-break points 20 ; wherein, ten clips 10 are pierced through each clip 10 . Reagent filling grooves 11, each reagent filling groove 11 is used for filling biological sample extraction reagents, and the bottom of each reagent filling groove 11 is a conical groove 12 that is wide at the top and narrow at the bottom. Secondly, the easily detachable points 20 are arranged between two adjacent clips 10 to connect the two adjacent clips 10 to each other. The reagents extracted from the biological samples are placed in the appropriate reagent filling tank 11 according to the conditions of different formulations, and can be stored for later use after being sealed with an aluminum film. After confirming the number of samples, the six clips 10 of the present creation can quickly prepare materials for a large number of samples. If the sample has an abnormal number, the easy breaking point 20 can be used to select an appropriate amount of reagents. After confirming the number of samples loaded, the sample and reagent holder can be installed on the automatic extraction apparatus.

請參照圖4,圖4為本新型實施例卡夾之側視圖。Please refer to FIG. 4 , which is a side view of the clip according to the new embodiment.

如圖3及圖4所示,該每一試劑充填槽11的一開口端111至該錐型槽12的底部具有一深度D,該深度D係為31.30~31.90毫米。其次,該些試劑充填槽11包括複數個第一試劑充填槽11a及複數個第二試劑充填槽11b,每一卡夾10具有一個第一試劑充填槽11a及九個第二試劑充填槽11b,該些第一試劑充填槽11a用以填充50μl~1.2mL的試劑,該第二試劑充填槽11b用以填充50μl~2.0mL的試劑。如圖4所示,該六個卡夾10的長度L係為100.93~101.53毫米,且透過該些易拆斷點20將該六個卡夾10相互連接以形成一寬度W,該寬度W係為105.98~106.58毫米。在本創作的一實施例中,相鄰兩卡夾10之間透過五個該些易拆斷點20連結;在本創作的另一實施例中,透過五個該些易拆斷點20將相鄰兩卡夾10分離。As shown in FIGS. 3 and 4 , each reagent filling groove 11 has a depth D from an open end 111 to the bottom of the tapered groove 12 , and the depth D is 31.30-31.90 mm. Next, the reagent filling grooves 11 include a plurality of first reagent filling grooves 11a and a plurality of second reagent filling grooves 11b, and each clip 10 has one first reagent filling groove 11a and nine second reagent filling grooves 11b, The first reagent filling grooves 11a are used for filling 50 μl˜1.2 mL of reagents, and the second reagent filling grooves 11b are used for filling 50 μl˜2.0 mL reagents. As shown in FIG. 4 , the length L of the six clips 10 is 100.93-101.53 mm, and the six clips 10 are connected to each other through the easily detachable points 20 to form a width W, and the width W is It is 105.98~106.58 mm. In an embodiment of the present invention, the two adjacent clips 10 are connected through five easily detachable points 20; The two adjacent clips 10 are separated.

綜上所述,本創作該試劑充填槽11可同時搭載十種不同試劑使用並可搭配生產自動化生物性檢體萃取儀使用。為配合大量檢體上樣,該六個卡夾10設計可大量節省備料時間,另外若遇到畸零數的檢體,可使用該易拆斷點20選擇所需要的試劑數量,將試劑有效使用。在生物性檢體純化試劑中,有配方會使用到少量試劑體積的狀況,此時便可使用本創作的體積縮減的該錐型槽12,該錐型槽12縮小錐形構造,可有效配合萃取儀的移液系統完成吸取少體積的試劑。To sum up, the reagent filling tank 11 of the present invention can be used with ten different reagents at the same time, and can be used in conjunction with the production automatic biological sample extraction apparatus. In order to cope with the loading of a large number of specimens, the design of the six clips 10 can save a lot of time for material preparation. In addition, if an abnormal number of specimens is encountered, the easy breaking point 20 can be used to select the required number of reagents, and the reagents can be used effectively. . In biological specimen purification reagents, there is a situation where a small amount of reagent volume is used in a recipe. At this time, the tapered groove 12 with a reduced volume of the present invention can be used. The tapered groove 12 has a reduced tapered structure, which can effectively cooperate with The pipetting system of the extractor completes the aspiration of small volumes of reagents.

上述實施例僅係為了方便說明而舉例而已,本創作所主張之權利範圍自應以申請專利範圍所述為準,而非僅限於上述實施例。The above-mentioned embodiments are only examples for the convenience of description, and the scope of rights claimed in this creation should be based on the scope of the patent application, rather than being limited to the above-mentioned embodiments.

1:非卡榫式試劑卡夾盤 10:卡夾 11:試劑充填槽 11a:第一試劑充填槽 11b:第二試劑充填槽 111:開口端 12:錐型槽 20:易拆斷點 1: Non-tenon reagent cartridge chuck 10: Card holder 11: Reagent filling tank 11a: The first reagent filling tank 11b: The second reagent filling tank 111: Open end 12: Tapered groove 20: Easy break point

圖1為本新型實施例非卡榫式試劑卡夾盤之立體示意圖; 圖2為本新型實施例非卡榫式試劑卡夾盤之底部立體示意圖; 圖3為本新型實施例非卡榫式試劑卡夾盤之仰視圖; 圖4為本新型實施例卡夾之側視圖。 Fig. 1 is the three-dimensional schematic diagram of the non-tenon-type reagent chuck of the novel embodiment; Fig. 2 is the bottom three-dimensional schematic diagram of the non-tenon-type reagent chuck of the novel embodiment; 3 is a bottom view of the non-tenon-type reagent chuck of the novel embodiment; FIG. 4 is a side view of the clip according to the new embodiment.

1:非卡榫式試劑卡夾盤 1: Non-tenon reagent cartridge chuck

10:卡夾 10: Card holder

11:試劑充填槽 11: Reagent filling tank

111:開口端 111: Open end

Claims (8)

一種非卡榫式試劑卡夾盤,包括: 六個卡夾,每一卡夾上穿設十個試劑充填槽,每一試劑充填槽用以填充生物性檢體萃取試劑,該每一試劑充填槽的底部係為一上寬下窄的錐型槽;以及 複數個易拆斷點,設置於相鄰兩卡夾之間,使相鄰的兩卡夾相互連。 A non-tenon type reagent cartridge chuck, comprising: There are six clips, ten reagent filling grooves are perforated on each clip, each reagent filling groove is used to fill biological sample extraction reagents, and the bottom of each reagent filling groove is a cone with a wide upper part and a narrow lower part. groove; and A plurality of easily dismantling points are arranged between two adjacent clips, so that the two adjacent clips are connected to each other. 如申請專利範圍第1項所述之非卡榫式試劑卡夾盤,其中, 該每一試劑充填槽的一開口端至該錐型槽的底部具有一深度D,該深度D係為31.30~31.90毫米。The non-tenon-type reagent cartridge according to claim 1, wherein an open end of each reagent filling groove has a depth D to the bottom of the tapered groove, and the depth D is 31.30~ 31.90 mm. 如申請專利範圍第1項所述之非卡榫式試劑卡夾盤,其中,該些試劑充填槽包括複數個第一試劑充填槽及複數個第二試劑充填槽。The non-tenon-type reagent cartridge according to claim 1, wherein the reagent filling grooves include a plurality of first reagent filling grooves and a plurality of second reagent filling grooves. 如申請專利範圍第3項所述之非卡榫式試劑卡夾盤,其中,該些第一試劑充填槽用以填充50μl~1.2mL的試劑。The non-tenon-type reagent cartridge according to item 3 of the patent application scope, wherein the first reagent filling grooves are used to fill 50 μl-1.2 mL of reagents. 如申請專利範圍第3項所述之非卡榫式試劑卡夾盤,其中,該第二試劑充填槽用以填充50μl~2.0mL的試劑。The non-tenon-type reagent cartridge according to item 3 of the patent application scope, wherein the second reagent filling groove is used to fill 50 μl-2.0 mL of reagent. 如申請專利範圍第1項所述之非卡榫式試劑卡夾盤,其中,該六個卡夾的長度L係為100.93~101.53毫米,且透過該些易拆斷點將該六個卡夾相互連接以形成一寬度W,該寬度W係為105.98~106.58毫米。The non-tenon-type reagent cartridge according to claim 1, wherein the length L of the six clips is 100.93 mm to 101.53 mm, and the six clips are connected to each other through the easy breaking points Connected to form a width W, the width W is 105.98~106.58 mm. 如申請專利範圍第1項所述之非卡榫式試劑卡夾盤,其中,相鄰兩卡夾之間透過五個該些易拆斷點連結。The non-tenon-type reagent cartridge as described in claim 1, wherein two adjacent cartridges are connected through five easily detachable points. 如申請專利範圍第7項所述之非卡榫式試劑卡夾盤,其中,透過五個該些易拆斷點並藉由一外力將相鄰兩卡夾分離。The non-tenon-type reagent cartridge chucking plate as described in claim 7, wherein two adjacent clips are separated by an external force through five of the easily detachable points.
TW111201950U 2022-02-25 2022-02-25 Non-tenon type regent clamp tray TWM628745U (en)

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