CN217060176U - Medicine dissolution instrument for medicine dissolution analysis - Google Patents
Medicine dissolution instrument for medicine dissolution analysis Download PDFInfo
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- CN217060176U CN217060176U CN202220815239.4U CN202220815239U CN217060176U CN 217060176 U CN217060176 U CN 217060176U CN 202220815239 U CN202220815239 U CN 202220815239U CN 217060176 U CN217060176 U CN 217060176U
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Abstract
The utility model discloses a drug dissolution instrument for drug dissolution analysis, which comprises a dissolution instrument body, wherein the bottom of the dissolution instrument body is provided with a base, the base is horizontally provided with a support frame, the support frame is provided with adjustable feet, the upper surface of the base is provided with a control cabinet, the control cabinet is provided with a vertically lifting driving part, the driving part is provided with a stirring shaft, the stirring shaft extends into a dissolution device arranged on the base, the stirring shaft is hollow, a temperature measuring device and a sampling device are arranged in the stirring shaft, the sampling device comprises a sampling tube arranged in the stirring shaft, the temperature measuring device is arranged in the sampling tube, the stability of the dissolution instrument is ensured, the use safety is enhanced to a great extent, the precision of a temperature detection result is improved, the sampling is more convenient, and the experimental efficiency is improved, the experimental results are accurate.
Description
Technical Field
The utility model relates to the technical field of medical equipment, in particular to a drug dissolution instrument for drug dissolution analysis.
Background
The dissolution instrument is an instrument for performing a drug dissolution experiment, and a precise control system consisting of a single-chip microcomputer is used for performing centralized control on each component; the drug dissolution test is used for evaluating the bioequivalence and bioavailability of the drug and is also an important index for evaluating the quality of the drug before clinical use. Before an oral medicament is put into use, a large number of test analyses are required to ensure the use safety of the medicament, and the dissolution rate is the rate and the degree of dissolution of the medicament under specified conditions and is an important index for evaluating the quality of a medicament, so a medicament dissolution instrument is required to perform test analysis on the medicament.
In the dissolution experiment process, the solvent needs to be sampled and the temperature is measured and recorded, the existing dissolution instrument needs to be stopped and then independently sampled when sampling is carried out, so that the whole implementation process is seriously influenced, and the operation difficulty is high and danger is easy to occur when sampling is carried out without stopping. Solvent temperature has key effect in the experiment, traditional appearance of dissolving out is when carrying out the degree of dissolving out experiment, in order to ensure the accuracy of experiment, only can feed back solvent temperature through control water bath temperature, because it separates to have the dissolution cup between solvent and the water bath, dissolve out the cup and have certain thermal resistance, consequently water bath temperature is not equal to solvent temperature, also use temperature probe to detect it, but because temperature probe's response time is slow, need during the sampling of solvent temperature submerge temperature probe in the solvent for a certain time, and temperature probe has the interference in this time quantum, thereby influence the going on of degree of dissolving out experiment.
Meanwhile, in laboratory use, the dissolution instrument is mostly placed on an operation table, but the existing dissolution instrument is not provided with a stabilizing device at the bottom, so that vibration and shaking are easy to occur in use, and the experimental result is seriously influenced.
SUMMERY OF THE UTILITY MODEL
The utility model aims to overcome the shortcoming that the dissolution instrument in the prior art is relatively fussy when light displacement and measured temperature and sample can take place when using, and provide a dissolution instrument for drug dissolution analysis.
The utility model discloses a realize through following technical scheme: the utility model provides an appearance is dissolved out to medicine for dissolution rate analysis, includes dissolves out the appearance body, the bottom of dissolving out the appearance body is provided with the base, the base is improved level and is provided with the support frame, be provided with adjustable lower margin on the support frame, the upper surface of base is provided with the switch board, be provided with the drive division of vertical lift on the switch board, be provided with the (mixing) shaft in the drive division, the (mixing) shaft stretches into in the dissolution device of setting on the base, the inside cavity of (mixing) shaft, just be provided with temperature measuring device and sampling device in the (mixing) shaft, sampling device is including setting up the sampling tube in the (mixing) shaft, temperature measuring device sets up in the sampling tube.
Furthermore, the adjustable ground feet comprise adjusting rods arranged at the end parts of the supporting frames, and fixing suckers are arranged at the bottoms of the adjusting rods.
Furthermore, horizontal bubble tubes are arranged in the transverse direction and the radial direction of the control cabinet.
Furthermore, the stirring shaft penetrates through the driving part, the top of the stirring shaft protrudes out of the upper surface of the driving part, and the stirring shaft is fixed with the driving part through the elastic screw cap.
Furthermore, the temperature measuring device comprises a thermometer, the thermometer is inserted into the sampling tube, and the length of the thermometer is greater than that of the sampling tube.
Further, the water drop type probe of the thermometer protrudes out of the bottom of the sampling tube, and the diameter of the probe is larger than that of the sampling tube.
Furthermore, be provided with the cushion on the bottom inner wall of sampling tube.
The beneficial effects of the utility model reside in that: horizontal installation has the support frame on the base, the support frame extends to the outside level of base, increase area of contact, use adjustable lower margin can furthest's the horizontal effect that keeps dissolving out the appearance when using, and then guarantee the circularity of assurance pivot when the stirring, prevent to produce the service failure, the bottom of adjusting the pole is fixed with fixed suction cup, the sucking disc can adsorb on the operation panel when using, and then prevent to dissolve out the appearance and produce the displacement on the operation panel under the circumstances of vibrations, strengthen the safety in utilization in very big degree, guarantee the accuracy of experimental result. The thermometer and the sampling tube are inserted in the rotating shaft, temperature measurement and sampling can be carried out under the condition of no shutdown, the operation difficulty is reduced, the precision of a temperature detection result is improved, meanwhile, sampling is more convenient, the experiment efficiency is improved, and the experiment result is accurate.
Drawings
Fig. 1 is a schematic view of the overall structure of the present invention;
FIG. 2 is a schematic view of a cross-sectional structure of a stirring shaft of the present invention;
wherein: 1. a base; 101. a control cabinet; 102. a drive section; 103. a dissolution apparatus; 2. a stirring shaft; 201. stirring blades; 202. a sampling tube; 203. a thermometer; 2031. a probe; 204. fixing a nut; 205. a spherical plug; 206. a rubber pad; 3. a support frame; 301. a suction cup; 302. adjusting a rod; 4. a bubble vial.
Detailed Description
In the description of the present invention, it should also be noted that, unless otherwise explicitly specified or limited, the terms "disposed," "mounted," "connected," and "connected" are to be construed broadly, and may be, for example, fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meaning of the above terms in the present invention can be understood as a specific case by those skilled in the art.
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative efforts all belong to the protection scope of the present invention.
Example 1
As shown in fig. 1-2: the utility model provides a medicine dissolution instrument for medicine dissolution analysis, includes and dissolves out the appearance body, and the bottom of dissolving out the appearance body is provided with base 1, and base 1 is the flat board, installs the buffering face in the bottom surface of base 1, and the buffering face can alleviate the vibrations of base 1 and operation panel when using, reduces vibration amplitude, improves the result of use. Horizontal installation has support frame 3 on base 1, and support frame 3 extends to base 1 outside level, increases area of contact to install adjustable lower margin on support frame 3, use adjustable lower margin can furthest's the horizontal effect that keeps dissolving out the appearance when using, and then guarantee the circularity of guaranteeing the pivot when the stirring, prevent to produce the service failure, strengthened the stability of dissolving out the appearance to a great extent. Wherein adjustable lower margin is including installing the regulation pole 302 at 3 tip of support frame, and the bottom of adjusting pole 302 is fixed with fixed sucking disc 301, and sucking disc 301 can adsorb on the operation panel when using, and then prevents to dissolve out the appearance and produce the displacement on the operation panel under the circumstances of vibrations, strengthens the safety in utilization in the very big degree, guarantees the accuracy of experimental result. The control cabinet 101 is fixed on the upper surface of the base 1, the level bubble tube 4 is installed on the control cabinet 101 in the transverse direction and the radial direction, when the dissolution instrument is installed and fixed, the bubble tube 4 can be used for adjusting the installation position of the adjusting rod 302 through the levelness on the bubble tube 4, and in the using process, whether the dissolution instrument is horizontal in the using process can be judged through the bubble position in the bubble tube before being used every time, the state of the dissolution instrument can be visually detected when being used every time, the detection before being used every time is convenient, the preparation efficiency before being used is improved, and the use by people is convenient.
Install the drive division 102 of vertical lift on switch board 101, install (mixing) shaft 2 on the drive division 102, install stirring leaf 201 in the bottom of (mixing) shaft 2, stirring shaft 2 stretches into and installs in the dissolution device 103 on base 1, rotate the stirring through driving motor drive (mixing) shaft 2 in the drive division 102, wherein (mixing) shaft 2 runs through drive division 102, stirring shaft 2 can reciprocate the position of fixing (mixing) shaft 2 as required in drive division 102, and therefore, the wide applicability, it is convenient to adjust, top salient in drive division 102's upper surface at (mixing) shaft 2, stirring shaft 2 is fixed with drive division 102 through the elasticity nut, use the elasticity nut to fix it when adjusting the fixed height of (mixing) shaft 2, it is convenient to adjust the structure, reduce the operation degree of difficulty.
Wherein the stirring shaft 2 is hollow, a temperature measuring device and a sampling device are arranged in the stirring shaft 2, wherein the sampling device comprises a sampling tube 202 movably inserted in the stirring shaft 2, the temperature measuring device is arranged in the sampling tube 202, the temperature measuring device comprises a thermometer 203, the thermometer 203 is inserted in the sampling tube 202, the sampling tube 202 is arranged at the top of the stirring shaft 2 through a fixing nut 204 when in use, the thermometer 203 is inserted into the sampling tube 202 from the bottom of the sampling tube 202 when in use, the thermometer 203 is fixed on the sampling tube 202 by a spherical plug 205 at the top, the length of the thermometer 203 is larger than that of the sampling tube 202, a rubber gasket 206 is arranged on the inner wall of the bottom of the sampling tube 202, a water drop type probe 2031 of the thermometer 203 protrudes out of the bottom of the sampling tube 202, the diameter of the probe 2031 is larger than that of the sampling tube 202, and the diameter of the probe 2031 is smaller than that of the inner wall of the rotating shaft when in use, when the thermometer 203 is taken out from the inside of the rotating shaft, a rubber ring is fixed on the inner wall of the sampling tube 202, the thermometer 203 is lifted upwards during sampling, the probe 2031 is abutted against the rubber pad 206 at the bottom of the sampling tube 202, and then partial solution in the thermometer 203 and the sampling tube 202 is reserved, when the sampling tube 202 and the thermometer 203 are taken out, the sampling tube 202 can be made of transparent material, the temperature number can be read through the sampling tube 202 directly, because the probe 2031 on the thermometer 203 is in direct contact with the solution, the detection precision is greatly improved, when the sampling tube 202 is taken out, the thermometer 203 is moved downwards, and then the taken sample solution flows out of the sampling tube 202, and then sample analysis is carried out on the sample solution. The thermometer 203 and the sampling tube 202 are inserted in the rotating shaft, temperature measurement and sampling can be carried out under the condition of no shutdown, the operation difficulty is reduced, the precision of a temperature detection result is improved, meanwhile, the sampling is more convenient, the experiment efficiency is improved, and the experiment result is accurate.
Finally, it should be noted that: although the present invention has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions on some technical features, and any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention should be included in the scope of the present invention.
Claims (7)
1. A medicine dissolution instrument for analyzing medicine dissolution rate is characterized in that: including dissolving out the appearance body, the bottom of dissolving out the appearance body is provided with the base, the base is improved level and is provided with the support frame, be provided with adjustable lower margin on the support frame, the upper surface of base is provided with the switch board, be provided with the drive division of vertical lift on the switch board, be provided with the (mixing) shaft in the drive division, the (mixing) shaft stretches into in the dissolving out device of setting on the base, the inside cavity of (mixing) shaft, just be provided with temperature measuring device and sampling device in the (mixing) shaft, sampling device is including setting up the sampling tube in the (mixing) shaft, temperature measuring device sets up in the sampling tube.
2. The drug dissolution apparatus for drug dissolution analysis of claim 1, wherein: the adjustable ground feet comprise adjusting rods arranged at the end parts of the supporting frames, and fixed suckers are arranged at the bottoms of the adjusting rods.
3. The drug dissolution apparatus for drug dissolution analysis of claim 1, wherein: and the control cabinet is transversely and radially provided with level bubble tubes.
4. The drug dissolution apparatus for drug dissolution analysis as claimed in claim 1, wherein: the stirring shaft penetrates through the driving part, the top of the stirring shaft protrudes out of the upper surface of the driving part, and the stirring shaft is fixed with the driving part through the elastic screw cap.
5. The drug dissolution apparatus for drug dissolution analysis of claim 4, wherein: the temperature measuring device comprises a thermometer, the thermometer is inserted into the sampling tube, and the length of the thermometer is greater than that of the sampling tube.
6. The drug dissolution apparatus for drug dissolution analysis of claim 5, wherein: the water drop type probe of the thermometer is protruded out of the bottom of the sampling tube, and the diameter of the probe is larger than that of the sampling tube.
7. The drug dissolution apparatus for drug dissolution analysis of claim 6, wherein: and a rubber pad is arranged on the inner wall of the bottom of the sampling tube.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202220815239.4U CN217060176U (en) | 2022-04-09 | 2022-04-09 | Medicine dissolution instrument for medicine dissolution analysis |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202220815239.4U CN217060176U (en) | 2022-04-09 | 2022-04-09 | Medicine dissolution instrument for medicine dissolution analysis |
Publications (1)
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CN217060176U true CN217060176U (en) | 2022-07-26 |
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Family Applications (1)
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CN202220815239.4U Active CN217060176U (en) | 2022-04-09 | 2022-04-09 | Medicine dissolution instrument for medicine dissolution analysis |
Country Status (1)
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CN (1) | CN217060176U (en) |
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2022
- 2022-04-09 CN CN202220815239.4U patent/CN217060176U/en active Active
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