CN219737448U - Medicine dissolving-out instrument - Google Patents
Medicine dissolving-out instrument Download PDFInfo
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- CN219737448U CN219737448U CN202320163614.6U CN202320163614U CN219737448U CN 219737448 U CN219737448 U CN 219737448U CN 202320163614 U CN202320163614 U CN 202320163614U CN 219737448 U CN219737448 U CN 219737448U
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- Prior art keywords
- dissolution
- water bath
- bath kettle
- cup
- supporting frame
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- 239000003814 drug Substances 0.000 title claims abstract description 29
- 229940079593 drug Drugs 0.000 title claims description 10
- 238000004090 dissolution Methods 0.000 claims abstract description 79
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 44
- 238000003756 stirring Methods 0.000 claims abstract description 35
- 239000007788 liquid Substances 0.000 claims abstract description 34
- 238000005086 pumping Methods 0.000 claims abstract description 8
- 238000000605 extraction Methods 0.000 claims description 19
- 230000000149 penetrating effect Effects 0.000 claims description 3
- 238000012360 testing method Methods 0.000 abstract description 12
- 238000000034 method Methods 0.000 abstract description 5
- 238000005259 measurement Methods 0.000 abstract description 4
- 239000000463 material Substances 0.000 description 4
- 101100298222 Caenorhabditis elegans pot-1 gene Proteins 0.000 description 3
- 239000002904 solvent Substances 0.000 description 3
- 238000004458 analytical method Methods 0.000 description 2
- 238000013401 experimental design Methods 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 238000010438 heat treatment Methods 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000007922 dissolution test Methods 0.000 description 1
- 238000012113 quantitative test Methods 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
Landscapes
- Sampling And Sample Adjustment (AREA)
Abstract
The utility model relates to the technical field of medicine dissolution, in particular to a medicine dissolution instrument which comprises a water bath kettle, wherein a plurality of dissolution cups are detachably arranged on the water bath kettle, and a stirring assembly and a liquid pumping assembly are respectively arranged corresponding to each dissolution cup; the water bath device comprises a water bath kettle, wherein each dissolution cup is provided with a supporting frame, the dissolution cup and a stirring assembly are detachably arranged on the supporting frame, lifting electric cylinders are connected to the supporting frame, a top cover plate is arranged on the water bath kettle, the lifting electric cylinders are fixedly arranged on the top cover plate, and the dissolution cup penetrates through the top cover plate in a sliding mode. The utility model can continuously test samples with different dissolution time requirements, does not need repeated operation, effectively reduces errors caused by manual repeated intervention in the test process, and has more accurate measurement results.
Description
Technical Field
The utility model relates to the technical field of medicine dissolution, in particular to a medicine dissolution instrument.
Background
Before the oral medicament is put into use, a large number of test analyses are required to ensure the use safety of the medicament, and the dissolution rate is an important index for evaluating the quality of the medicament, so that a medicament dissolution instrument is required to perform the test analyses of the medicament. The existing dissolution instrument needs to wait for the stirring rod to stop rotating after stirring, heating and dissolving the medicament, take the stirring rod out of the dissolution cup, and then extract the medicament solution from the dissolution cup, so that more time is consumed, and the accuracy of experimental results is affected.
For this reason, chinese patent CN217180850U discloses a medicine dissolving-out appearance, belongs to dissolving-out appearance technical field, including casing, base and dissolving-out cup, the casing fixed mounting is in on the base, dig in the casing and be equipped with the water bath, water bath bottom fixed mounting heater, fixed mounting has flexible motor in the casing, the output fixed mounting of flexible motor has electric telescopic handle, electric telescopic handle top fixed mounting has the footstock, the top surface fixed mounting of footstock has rotation motor and cylinder, first gear and second gear are installed to the footstock rotation, the top of first gear with rotation motor's output fixed connection, the bottom surface fixed mounting of second gear has the (mixing) shaft, the cylinder intercommunication has the needle tubing of buckling, buckling the needle tubing stretches into the opening in the stirring leaf and stretches out from the mouth of pipe of stirring She Deduan, the utility model can in time extract the solvent of detecting from dissolving-out cup.
However, the above technical solution still has the following drawbacks: when the multivariate comparison test is performed, the dissolution time is set to have a certain difference for comparison, so that all dissolution cups cannot be simultaneously stopped to be taken out, and a second batch of experiments are performed, and if the two operation processes are different, a larger experiment result error is easily caused, so that a dissolution instrument is needed to solve the problems.
Disclosure of Invention
The utility model aims to solve the technical problem of providing a medicine dissolution instrument, which can be used for continuously testing samples with different dissolution time requirements, does not need repeated operation, effectively reduces errors caused by manual repeated intervention in the testing process, and has more accurate measurement results.
In order to solve the technical problems, the utility model adopts the following technical scheme:
the medicine dissolving-out instrument comprises a water bath kettle, wherein a plurality of dissolving-out cups are detachably arranged on the water bath kettle, and a stirring assembly and a liquid pumping assembly are respectively arranged corresponding to each dissolving-out cup; the water bath device comprises a water bath kettle, wherein each dissolution cup is provided with a supporting frame, the dissolution cup and a stirring assembly are detachably arranged on the supporting frame, lifting electric cylinders are connected to the supporting frame, a top cover plate is arranged on the water bath kettle, the lifting electric cylinders are fixedly arranged on the top cover plate, and the dissolution cup penetrates through the top cover plate in a sliding mode.
Further, the stirring assembly comprises a stirring rod, a stirring motor is connected and installed on the stirring rod, the stirring motor is fixedly installed on a supporting plate, and the supporting plate is detachably connected and installed with the supporting frame.
Further, a threaded convex ring is arranged at the bottom of the supporting plate, a threaded groove is formed in the supporting frame corresponding to the threaded convex ring, and the supporting plate and the supporting frame are in threaded connection with the threaded convex ring and the threaded groove.
Further, the liquid extraction assembly comprises a liquid extraction pipe penetrating through the supporting plate, the liquid extraction pipe is close to the inner wall of the dissolution cup and is inserted into the dissolution cup, and a liquid extraction pump is arranged on the liquid extraction pipe.
Further, a heater is arranged in the water bath kettle, and a liquid inlet pipe and a liquid outlet pipe are further connected to the water bath kettle.
Further, the bottom of the water bath kettle is also provided with a leveling base.
The utility model has the beneficial effects that:
in an actual use scenario, the dissolution instrument is suitable for measuring the dissolution of different dissolution times or simultaneously measuring the dissolution of different samples; preheating a water bath, controlling a lifting electric cylinder to drive a supporting frame to lift, installing a dissolution cup filled with a solvent on the supporting frame, wherein the dissolution cup is positioned outside the water bath at the moment, rapidly throwing a fixed amount of medicine into a plurality of dissolution cups respectively, then rapidly installing a stirring assembly and a liquid pumping assembly on the supporting frame to fix, simultaneously operating and controlling the lifting electric cylinder of each dissolution cup to put the dissolution cup into the water bath, starting a stirring device to stir and dissolve, after a certain time according to the actual experimental design requirement, controlling the dissolution cup required by driving to move out of the water bath, and controlling the liquid pumping assembly to rapidly sample and detect, wherein the medicine in the rest dissolution cups is still subjected to uninterrupted dissolution until the set time is reached; compared with the operation of taking out the materials together and putting the materials into the water bath kettle for the second time in the prior art, the influence of intermediate operation errors is reduced. The utility model can continuously test samples with different dissolution time requirements, does not need repeated operation, effectively reduces errors caused by manual repeated intervention in the test process, and has more accurate measurement results.
Drawings
FIG. 1 is a schematic view of the overall cross-sectional structure of the present utility model;
FIG. 2 is an enlarged schematic view of FIG. 1A according to the present utility model.
Detailed Description
The utility model will be further described with reference to examples and drawings, to which reference is made, but which are not intended to limit the scope of the utility model.
As shown in fig. 1-2, the utility model provides a medicine dissolution instrument, which comprises a water bath pot 1, wherein a plurality of dissolution cups 2 are detachably arranged on the water bath pot 1, and a stirring component 3 and a liquid extraction component 4 are respectively arranged corresponding to each dissolution cup 2; the water bath kettle is characterized in that a supporting frame 22 is arranged corresponding to each dissolution cup 2, the dissolution cups 2 and the stirring assembly 3 are detachably mounted on the supporting frame 22, lifting electric cylinders 23 are connected to the supporting frame 22, a top cover plate 11 is arranged on the water bath kettle 1, the lifting electric cylinders 23 are fixedly mounted on the top cover plate 11, and the dissolution cups 2 penetrate through the top cover plate 11 in a sliding mode.
In this embodiment, the dissolution instrument is suitable for measuring the dissolution rates of different dissolution times, or simultaneously measuring the dissolution rates of different samples; preheating a water bath 1, controlling a lifting electric cylinder 23 to drive a supporting frame 22 to lift, installing dissolution cups 2 filled with solvent on the supporting frame 22, at the moment, placing the dissolution cups 2 outside the water bath 1, rapidly putting quantitative good medicines into the dissolution cups 2 respectively, rapidly installing a stirring assembly 3 and a liquid extraction assembly 4 on the supporting frame 22 for fixing, simultaneously operating the lifting electric cylinder 23 for controlling each dissolution cup 2 to put the dissolution cup 2 into the water bath 1, starting a stirring device 3 for stirring and dissolution, controlling the dissolution cups 2 required to be driven to move out of the water bath 1 after a certain time according to actual experimental design requirements, controlling the liquid extraction assembly 4 for rapid sampling detection, and continuously dissolving medicines in the rest dissolution cups 2 until the set time is reached; compared with the operation of taking out the materials together and putting the materials into the water bath kettle for the second time in the prior art, the influence of intermediate operation errors is reduced. The dissolution instrument can be used for continuously testing samples with different dissolution time requirements, repeated operation is not needed, errors caused by repeated manual intervention in the testing process are effectively reduced, and the measurement result is more accurate.
As shown in fig. 2, the stirring assembly 3 includes a stirring rod 31, a stirring motor 32 is mounted on the stirring rod 31 in a connection manner, the stirring motor 32 is fixedly mounted on a supporting plate 33, and the supporting plate 33 is detachably mounted on the supporting frame 22; in this embodiment, the stirring rod 31 is detachably mounted on the supporting frame 22 by using the supporting plate 33, so that in actual use, the stirring rod is convenient to detach, and the independent stirring motor 32 controls the medicine in the single dissolution cup 2 to dissolve out, so that the dissolution work of other dissolution cups is not affected when the single dissolution cup 2 needs to be taken out for testing, and the stirring rod is more practical and independent.
As shown in fig. 2, a threaded protruding ring 331 is provided at the bottom of the supporting plate 33, a threaded groove 332 is provided on the supporting frame 22 corresponding to the threaded protruding ring 331, and the supporting plate 33 and the supporting frame 32 are screwed with each other by using the threaded protruding ring 331 and the threaded groove 332; in this embodiment, the supporting plate 33 and the supporting frame 32 are in threaded connection with the threaded convex ring 331 and the threaded groove 332, so that the operation is convenient, the connection is stable, and the normal stirring operation is ensured.
As shown in fig. 2, the liquid extraction assembly 4 includes a liquid extraction tube 41 penetrating through the support plate 33, the liquid extraction tube 41 is inserted into the dissolution cup 2 close to the inner wall of the dissolution cup 2, and a liquid extraction pump 42 is disposed on the liquid extraction tube 41; in this embodiment, the electric liquid pump 42 is directly used for liquid pumping, so that the liquid pumping is faster, the fine quantitative test is performed after the liquid pumping, the continuous dissolution time of the medicine is reduced, and the timed dissolution test is facilitated.
As shown in FIG. 1, a heater 12 is arranged in the water bath pot 1, and a liquid inlet pipe 14 and a liquid outlet pipe 15 are also connected to the water bath pot 12. The bottom of the water bath kettle 1 is also provided with an adjustable base 13; in the embodiment, the water bath 1 adopts a conventional structure, has heating and water inlet and outlet functions, and is also provided with a base 13 which can be leveled, so as to ensure the normal use of the dissolution device in the water bath.
All technical features in the present embodiment can be modified in appearance according to actual needs.
The foregoing embodiments are preferred embodiments of the present utility model, and in addition, the present utility model may be implemented in other ways, and any obvious substitution is within the scope of the present utility model without departing from the concept of the present utility model.
Claims (6)
1. A drug dissolution instrument, characterized in that: the water bath kettle comprises a water bath kettle (1), wherein a plurality of dissolution cups (2) are detachably arranged on the water bath kettle (1), and a stirring assembly (3) and a liquid pumping assembly (4) are respectively arranged corresponding to each dissolution cup (2);
the water bath device comprises a water bath kettle (1), wherein each dissolution cup (2) is provided with a supporting frame (22), each dissolution cup (2) and each stirring assembly (3) are detachably installed on each supporting frame (22), each supporting frame (22) is connected with a lifting electric cylinder (23), each water bath kettle (1) is provided with a top cover plate (11), each lifting electric cylinder (23) is fixedly installed on each top cover plate (11), and each dissolution cup (2) penetrates through each top cover plate (11) in a sliding mode.
2. A drug dissolution apparatus according to claim 1, wherein: stirring subassembly (3) are including puddler (31), connect on puddler (31) and install agitator motor (32), agitator motor (32) fixed mounting is on backup pad (33), backup pad (33) with support frame (22) detachable connection installs.
3. A drug dissolution apparatus according to claim 2, wherein: the bottom of backup pad (33) is equipped with screw thread bulge loop (331), correspond on support frame (22) screw thread bulge loop (331) are equipped with screw thread groove (332), backup pad (33) and support frame (22) utilize screw thread bulge loop (331) and screw thread groove (332) threaded connection.
4. A drug dissolution apparatus according to claim 1, wherein: the liquid extraction assembly (4) comprises a liquid extraction pipe (41) penetrating through the supporting plate (33), the liquid extraction pipe (41) is close to the inner wall of the dissolution cup (2), the dissolution cup (2) is inserted into the liquid extraction pipe (41), and a liquid extraction pump (42) is arranged on the liquid extraction pipe (41).
5. A drug dissolution apparatus according to claim 1, wherein: the water bath kettle (1) is internally provided with a heater (12), and the water bath kettle (1) is also connected with a liquid inlet pipe (14) and a liquid outlet pipe (15).
6. A drug dissolution apparatus according to claim 1, wherein: the bottom of the water bath kettle (1) is also provided with a leveling base (13).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202320163614.6U CN219737448U (en) | 2023-02-09 | 2023-02-09 | Medicine dissolving-out instrument |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202320163614.6U CN219737448U (en) | 2023-02-09 | 2023-02-09 | Medicine dissolving-out instrument |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN219737448U true CN219737448U (en) | 2023-09-22 |
Family
ID=88031800
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202320163614.6U Active CN219737448U (en) | 2023-02-09 | 2023-02-09 | Medicine dissolving-out instrument |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN219737448U (en) |
-
2023
- 2023-02-09 CN CN202320163614.6U patent/CN219737448U/en active Active
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