CN216984971U - Nasal nerve skull base repairing device and skull base repairing film - Google Patents
Nasal nerve skull base repairing device and skull base repairing film Download PDFInfo
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- CN216984971U CN216984971U CN202122981046.4U CN202122981046U CN216984971U CN 216984971 U CN216984971 U CN 216984971U CN 202122981046 U CN202122981046 U CN 202122981046U CN 216984971 U CN216984971 U CN 216984971U
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Abstract
The utility model relates to a cranial base repair device and a cranial base repair membrane through nasal nerves, which comprise a first repair membrane component for repairing a lilieequest membrane leakage opening and a second repair membrane component for repairing a dural membrane leakage opening. The transnasal nerve skull base repairing device and the skull base repairing membrane have the advantages that the fusible biomembrane, the non-fusible biomembrane, the supporting piece, the hemostatic yarn and the fixing air bag are matched for use, so that the technical scheme has compact structure, strong clinical practicability and obvious effect, adopts the multilayer artificial biomembrane, assists artificial supporting and fixing materials, successfully realizes skull base repairing, prevents complication cerebrospinal fluid leakage after the transnasal neuroendoscopy operation, reduces the risk of intracranial infection, reduces the possibility of endangering the life of a patient, improves the life quality of the patient and improves the prognosis; moreover, the method adopts artificial materials in the repairing process.
Description
Technical Field
The utility model relates to the technical field of skull base repair, in particular to a nasal nerve skull base repair device and a skull base repair membrane.
Background
The transnasal neuroendoscopy operation has the advantages of wide operation visual angle, high illumination intensity, strong direct vision, small wound and the like, so the transnasal neuroendoscopy operation is widely applied to excision and treatment of intracranial saddle area space-occupying lesions (such as pituitary adenoma, craniopharyngioma, Rathke cyst, meningioma and the like). Generally, the skull base bone, the dura mater and the liliequiest membrane are damaged to different degrees when the nasal neuroendoscopy operation is carried out, so that postoperative complications such as cerebrospinal fluid leakage are increased; therefore, the postoperative repair of the skull base under the nasal neuroendoscope has important practical application value for preventing the occurrence of cerebrospinal fluid leakage.
At present, one of the conventional methods for repairing the skull base of the postoperative transnasal neuroendoscope is to adopt autologous tissues to repair the skull base, wherein the autologous tissues commonly comprise nasal cavity mucosa flap, fascia lata, abdominalis rectus sheath, fat, muscle and the like. The repair method needs to take the tissues of a patient (the 22 th volume of 2019, vol.22, vol.15, pp.1689 to 1693 of the journal of practical neurological diseases in China, and clinical analysis of neuroendoscopy for traumatic cerebrospinal rhinorrhea), but the method can damage the normal anatomical structure of the relevant parts, further causes olfactory damage, nasal cavity defense function loss, dyspnea, skin sensory loss, incision infection, poor incision healing, muscle damage, muscle pain, limb movement disorder caused by poor incision healing for a long time, deep venous thrombosis and the like, and influences the judgment of whether or not the postoperative saddle area lesion recurs (the imaging causes confusion).
In recent years, with the development and maturity of artificial dura mater technology, the combination of autologous tissues and artificial dura mater under neuroendoscopy is also one of the common methods for repairing skull base [ the exploration on the reason and treatment of the failure of cerebrospinal fluid leakage repair by neuroendoscopic transnasal pituitary tumor operation from page 86 to page 92 of No. 2 of volume 13 in 2016 of clinical neurosurgery ], but this method still has the disadvantage of damaging autologous tissues.
It can be seen that there is a need in the art to develop a novel inferior cranial base repair device via transnasal neuroendoscopy that addresses the above-mentioned problems.
SUMMERY OF THE UTILITY MODEL
In view of this, the utility model aims to provide a transnasal nerve skull base repairing device and a skull base repairing film, so as to solve the problem that postoperative repair of a transnasal nerve endoscope skull base is inconvenient in the prior art.
The utility model is realized by the following technical scheme:
one of the present invention:
the cranial base repair device for the nasal nerve comprises a first repair membrane assembly for repairing a lilieequest membrane leakage opening and a second repair membrane assembly for repairing a dura mater leakage opening.
Further, the first repairing membrane assembly and the second repairing membrane assembly comprise a fusible biological membrane and a non-fusible biological membrane which is matched with the fusible biological membrane for use.
Further, the first repairing membrane assembly also comprises a supporting piece, and the supporting piece is attached to the fusible biological membrane of the first repairing membrane assembly and is used for supporting the fusible biological membrane.
Further, the second repair membrane assembly also comprises hemostatic yarns, and the hemostatic yarns are matched with the non-fusible biomembrane of the second repair membrane assembly and are attached to the non-fusible biomembrane.
Further, the second repair membrane assembly further comprises a fixing air bag used for fixing the hemostatic yarns, and the fixing air bag is attached to the hemostatic yarns.
The second invention is:
the skull base repairing film, the fusible biomembrane is a heterogenous acellular dermal matrix, and the non-fusible biomembrane is a B-type dura mater repairing material.
The third invention:
the skull base repairing film, the support piece is gelatin sponge.
The utility model has the beneficial effects that:
the transnasal nerve skull base repairing device and the skull base repairing membrane have the advantages that the fusible biomembrane, the non-fusible biomembrane, the supporting piece, the hemostatic yarn and the fixing air bag are matched for use, so that the technical scheme has compact structure, strong clinical practicability and obvious effect, adopts the multilayer artificial biomembrane, assists artificial supporting and fixing materials, successfully realizes skull base repairing, prevents complication cerebrospinal fluid leakage after the transnasal neuroendoscopy operation, reduces the risk of intracranial infection, reduces the possibility of endangering the life of a patient, improves the life quality of the patient and improves the prognosis; moreover, the method adopts artificial materials in the repairing process, so that the normal anatomical structure of the relevant part can not be damaged, and complications such as olfactory loss, limb movement disorder and the like can not be caused; more importantly, the method does not use autologous tissues to repair the skull base, and does not influence the interpretation result of the iconography in the follow-up process, thereby improving the accuracy of the doctor in judging whether the saddle region lesion is resected and whether the lesion is relapsed or not.
Additional advantages, objects, and features of the utility model will be set forth in part in the description which follows and in part will become apparent to those having ordinary skill in the art upon examination of the following or may be learned from practice of the utility model. The objectives and other advantages of the utility model may be realized and attained by the means of the instrumentalities and combinations particularly pointed out hereinafter.
Drawings
FIG. 1 is a schematic view of a first repair membrane module of the present invention;
FIG. 2 is a schematic view of a second prosthetic membrane module of the present invention;
fig. 3 is a schematic view of the use flow of the repairing device of the present invention.
In the figure: 1. a first repair membrane module; 2. a fusible biofilm; 3. a non-fusible biofilm; 4. a support member; 5. a second repair membrane module; 6. a hemostatic yarn; 7. the air bag is fixed.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are some, but not all, embodiments of the present invention. The components of embodiments of the present invention generally described and illustrated in the figures herein may be arranged and designed in a wide variety of different configurations.
Thus, the following detailed description of the embodiments of the present invention, as presented in the figures, is not intended to limit the scope of the utility model, as claimed, but is merely representative of selected embodiments of the utility model. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
It should be noted that: like reference numbers and letters refer to like items in the following figures, and thus, once an item is defined in one figure, it need not be further defined and explained in subsequent figures.
In the above description of the present invention, it should be noted that the terms "one side", "the other side" and the like indicate the orientation or positional relationship based on the orientation or positional relationship shown in the drawings or the orientation or positional relationship which is usually placed when the utility model is used, and are only for convenience of describing the present invention and simplifying the description, but do not indicate or imply that the device or the element which is referred to must have a specific orientation, be constructed in a specific orientation and operation, and thus, should not be construed as limiting the present invention. Furthermore, the terms "first," "second," and the like are used merely to distinguish one description from another, and are not to be construed as indicating or implying relative importance.
Further, the term "identical" and the like do not mean that the components are absolutely required to be identical, but may have slight differences. The term "perpendicular" merely means that the positional relationship between the components is more perpendicular than "parallel", and does not mean that the structure must be perfectly perpendicular, but may be slightly inclined.
The utility model is one of:
referring to fig. 1-2, the present invention provides a technical solution: the cranial nerve transnasal cranial base repair device comprises a first repair membrane component 1 for repairing a lilieequest membrane leakage opening and a second repair membrane component 5 for repairing a dura mater leakage opening;
the first repairing membrane component 1 and the second repairing membrane component 5 both comprise a fusible biological membrane 2 and a non-fusible biological membrane 3 which is matched with the fusible biological membrane 2 for use, the fusible biological membrane of the first repairing membrane component is arranged at the bottom of the three ventricles, and the inner side of the fusible biological membrane is close to and covers a li-equest membrane leakage opening at the bottom of the third ventricles for growing and fusing with the bottom of the three ventricles to prevent high-flow cerebrospinal fluid from leaking into the interpeduncular pool due to the impact of the cerebrospinal fluid;
the first repairing membrane component 1 further comprises a supporting piece 4, after the fusible biomembrane of the first repairing membrane component is placed, the supporting piece is placed in the tumor cavity, the inner side of the supporting piece is close to and supports the fusible biomembrane of the first repairing membrane component, and the fusible biomembrane is further close to and covers a lilieequest membrane leakage opening at the bottom of the third ventricle, so that the function of preventing high-flow cerebrospinal fluid from leaking to the interpeduncular pond is further achieved, the filling amount of the supporting piece is about 80% -85% of the space of the tumor cavity, the supporting piece is used for supporting the adjacent fusible biomembrane and does not press the optic nerve in the saddle region and the aqueduct at the bottom of the third ventricle (the gelatin sponge expands when water is used, if the filling amount is too large, the gelatin sponge can bend the fusible biomembrane to the third ventricle, so that the aqueduct at the bottom of the third ventricle is blocked, and normal circulation of the cerebrospinal fluid cannot be caused);
after the support member and the fusible biomembrane are placed completely, the non-fusible biomembrane of the first repair component is placed under the dura mater, the inner side of the non-fusible biomembrane is tightly attached to the support member, and the outer side of the non-fusible biomembrane is tightly attached to and covers the dura mater leak opening, so that the non-fusible biomembrane is used for reducing the leakage of a small amount of cerebrospinal fluid in the interpeduncular pond to the sphenoid sinus region;
after the first repairing membrane component is placed, the second repairing membrane component is taken out for use, the fusible biomembrane of the second repairing membrane component is placed outside the dura mater, the inner side of the fusible biomembrane is tightly attached to and covers the dura mater leak opening and is used for growing and fusing with the dura mater to form sealing and prevent a small amount of cerebrospinal fluid in the interpeduncular pool from leaking to the sphenoid sinus area, the non-fusible biomembrane of the second repairing membrane component is placed outside the dura mater, the inner side of the non-fusible biomembrane is tightly attached to and covers the fusible biomembrane and is used for preventing the fusible biomembrane from sliding and further reducing the leakage of the small amount of cerebrospinal fluid in the interpeduncular pool to the sphenoid sinus area;
the second repairing membrane component 5 also comprises hemostatic yarns 6, after the placement of the fusible biomembrane and the non-fusible biomembrane is finished, the hemostatic yarns 6 are placed in the sphenoid sinus area and fill the sphenoid sinus, and the inner side of the hemostatic yarns is close to and presses the non-fusible biomembrane of the second repairing membrane component to prevent the non-fusible biomembrane from sliding;
the second repairing membrane component 5 also comprises a fixing air bag 7 for fixing the hemostatic yarns 6, the fixing air bag 7 is arranged in the nasal cavity, the periphery of the fixing air bag is close to the nasal cavity, and the inner side of the fixing air bag is close to and supports the hemostatic yarns, so that the effect of preventing the hemostatic yarns from shifting is achieved;
it should be further explained that all the above operation steps need to be operated under the guidance of a neuroendoscope, and as for the operation method and the use principle of the inner diameter of the nerve, which are the prior art in the field, those skilled in the art can implement the above technical scheme without creative labor and thinking on the basis of mastering the prior art.
The second invention is:
the skull base repairing membrane can be derived from skin tissues of cattle, realizes the purposes of degreasing, decellularization and impurity protein removal by a chemical method, and is prepared by a freeze drying technology and can absorb the xenogeneic acellular dermal matrix which keeps the natural microstructure of collagen; the non-fusible biomembrane is prepared from bovine pericardium tissue through modification such as epoxide fixation, multi-azimuth antigen removal treatment, protein molecule modification and toughening, adhesion, surface functionalization treatment for enriching growth factors and the like, and has the functions of gathering in-situ stem cells and growth factors released by a self-repairing mechanism and conveyed to an implanted part, inducing tissue regeneration and finally regenerating defective dura mater tissue.
The third invention:
the basis cranii repair membrane, support 4 are gelatin sponge.
The fourth aspect of the utility model:
referring to fig. 3, the method for using the repairing device includes the following steps,
1) material preparation;
I. the preparation of the fusible biological membrane 2 is from skin tissues of cattle, realizes the purposes of degreasing, decellularization and deproteinization by a chemical method, and prepares the absorbable xenogenous acellular dermal matrix which keeps the natural microstructure of collagen by a freeze drying technology;
II, preparing a non-fusible biomembrane 3, wherein the non-fusible biomembrane is prepared from a bovine pericardium tissue by modification such as epoxide fixation, multi-azimuth antigen removal treatment, protein molecule modification and toughening, adhesion, growth factor enrichment surface functionalization treatment and the like, and has the functions of collecting stem cells and growth factors released by a self-repairing mechanism in situ and conveyed to an implantation part, inducing tissue regeneration and finally regenerating a defective dura mater tissue;
2) repairing a lilieequest film leakage opening;
I. the fusible biomembrane 2 of the first repairing membrane component 1 is placed at the repairing part and at the bottom of the three ventricles, the inner side of the fusible biomembrane is close to and covers the li-equest membrane leakage opening at the bottom of the third ventricles, and the fusible biomembrane is used for growing and fusing with the bottom of the three ventricles to prevent high-flow cerebrospinal fluid from leaking to the interpeduncular pool due to the impact of the cerebrospinal fluid;
II, placing a support piece 4 at a position to be used, supporting and fixing the fusible biomembrane 2 of the first repairing membrane component 1, placing the support piece in the tumor cavity, pressing close to and supporting the fusible biomembrane of the first repairing membrane component at the inner side of the tumor cavity, further pressing close to and covering a liliequiest membrane leakage opening at the bottom of a third ventricle, further playing a role in preventing high-flow cerebrospinal fluid from leaking to an interpeduncular pond in a large quantity, wherein the filling amount of the support piece is about 80-85% of the space of the tumor cavity, and the support piece is used for supporting the fusible biomembrane and does not press an optic nerve in the saddle region and a aqueduct at the bottom of the third ventricle. (gelatin sponge swells when water is available, and if the filling amount is too large, the gelatin sponge can bend the fusible biomembrane towards the third ventricle, so that the aqueduct at the bottom of the third ventricle is blocked, and cerebrospinal fluid cannot normally circulate);
III, placing the non-fusible biomembrane 3 of the first repairing membrane component 1 at the use position, tightly attaching to the support component 4, placing under the dura mater, wherein the inner side is tightly attached to the support component, and the outer side is tightly attached to and covers the dura mater leak orifice, so as to reduce the leakage of a small amount of cerebrospinal fluid in the interpeduncular pool to the sphenoid sinus area;
3) repairing the dural leak;
I. the fusible biomembrane 2 of the second repairing membrane component 5 is placed at the repairing part and outside the dura mater, the inner side of the fusible biomembrane is tightly attached to and covers the dura mater leak opening for growing and fusing with the dura mater to form sealing, and a small amount of cerebrospinal fluid in the interpeduncular pool is prevented from leaking to the sphenoid sinus area;
II, placing the non-fusible biomembrane 3 of the second repairing membrane component 5 at the use position, clinging to and covering the adjacent fusible biomembrane, placing the membrane outside the dura mater, clinging to and covering the adjacent fusible biomembrane 4 at the inner side, and preventing the fusible biomembrane from sliding so as to further reduce the leakage of a small amount of cerebrospinal fluid in the interpeduncular pool to the sphenoid sinus region.
In this embodiment: in the step 3, the hemostatic yarns 6 support and limit the non-fusible biomembrane 3 at the second repairing membrane component 5, the hemostatic yarns 6 are arranged in the sphenoid sinus region and fill the sphenoid sinus, and the inner side of the hemostatic yarns is close to and presses the non-fusible biomembrane 5 of the second repairing membrane component to prevent the non-fusible biomembrane 5 from sliding.
In this embodiment: in the step 3, the hemostatic yarns 6 are further fixed by the air bag, the fixed air bag 7 is arranged in the nasal cavity, the periphery of the fixed air bag is close to the nasal cavity, and the inner side of the fixed air bag is close to and supports the hemostatic yarns 6, so that the hemostatic yarns 6 are prevented from moving.
Finally, the above embodiments are only for illustrating the technical solutions of the present invention and not for limiting, although the present invention has been described in detail with reference to the preferred embodiments, it should be understood by those skilled in the art that modifications or equivalent substitutions may be made to the technical solutions of the present invention without departing from the spirit and scope of the technical solutions of the present invention, and all of them should be covered in the claims of the present invention.
Claims (4)
1. Neural skull base prosthetic devices of intranasal, its characterized in that: the repairing membrane comprises a first repairing membrane component (1) for repairing a lilieequest membrane leakage opening and a second repairing membrane component (5) for repairing a dura mater leakage opening;
the first repairing membrane component (1) and the second repairing membrane component (5) both comprise a fusible biological membrane (2) and a non-fusible biological membrane (3) which is matched with the fusible biological membrane (2) for use;
the first repairing membrane assembly (1) further comprises a supporting piece (4), and the supporting piece (4) is attached to the fusible biological membrane (2) of the first repairing membrane assembly (1) and used for supporting the fusible biological membrane (2);
the second repairing membrane assembly (5) further comprises hemostatic yarns (6), and the hemostatic yarns (6) are matched with the non-fusible biological membrane (3) of the second repairing membrane assembly (5) and are attached to the non-fusible biological membrane (3).
2. The transnasal nerve cranial base repair device of claim 1, wherein: the second repairing film assembly (5) further comprises a fixing air bag (7) used for fixing the hemostatic yarn (6), and the fixing air bag (7) is attached to the hemostatic yarn (6).
3. A cranial base repair membrane incorporating the transnasal nerve cranial base repair device of claim 1 or 2, wherein: the fusible biomembrane (2) is a heterogenous acellular dermal matrix, and the non-fusible biomembrane (3) is a B-type dura mater repairing material.
4. A cranial base repair membrane incorporating the transnasal nerve cranial base repair device of claim 1, wherein: the supporting piece (4) is gelatin sponge.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202122981046.4U CN216984971U (en) | 2021-12-01 | 2021-12-01 | Nasal nerve skull base repairing device and skull base repairing film |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202122981046.4U CN216984971U (en) | 2021-12-01 | 2021-12-01 | Nasal nerve skull base repairing device and skull base repairing film |
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| CN216984971U true CN216984971U (en) | 2022-07-19 |
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| CN202122981046.4U Active CN216984971U (en) | 2021-12-01 | 2021-12-01 | Nasal nerve skull base repairing device and skull base repairing film |
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