CN216954978U

CN216954978U - Flow cell system

Info

Publication number: CN216954978U
Application number: CN202123231220.XU
Authority: CN
Inventors: 魏枫; 左金鹏; 刘中婵; 刘欢
Original assignee: Shanghai Focs Analytical Instruments Co ltd
Current assignee: Shanghai Focs Analytical Instruments Co ltd
Priority date: 2021-12-21
Filing date: 2021-12-21
Publication date: 2022-07-12
Anticipated expiration: 2031-12-21

Abstract

The utility model discloses a flow cell system which is characterized by comprising a metering pump, a flow cell, a buffer bottle, a collecting tank and a detection system. The metering pump is used for providing power for the circulating pond system. The flow cell is used for dissolving out the working medium. The buffer bottle is used for stabilizing the flow rate of the working medium. The collecting tank is communicated with the buffer bottle flow cell through a closed-open ring sampling pipeline to collect working media in the flow cell, and a sampling closed-loop open-ring valve sampling pump-in pump-out pump valve is arranged on the open-close ring sampling pipeline. The detection system comprises a second gravity detection system disposed at the bottom of the collection trough to detect a rate of weight change of the collection trough and configured to issue an alarm when the rate of weight change is below a predetermined threshold. The second gravity detection system can detect whether the open-loop pipeline is blocked or not, and meanwhile, the second gravity detection system can be used for calibrating the flow of the metering pump.

Description

Circulation pond system

Technical Field

The utility model relates to the technical field of medical experimental equipment application, in particular to a flow cell system.

Background

With the continuous development of detection technology, a flow cell method is increasingly adopted for detecting the dissolution rate of liquid, a common flow cell system generally comprises a medium storage, a piston pump, a flow cell, a sampling system, a sample collector and the like, and in the specific application process, the flow cell method adopted by a tester is divided into a closed loop method and an open loop method.

The test samples tested by the flow cell method carry particles in some cases, and the presence of these particles can easily lead to clogging of the tubing. If these particles accumulate in large amounts in core components in the flow cell system, such as metering pumps (e.g. ceramic pumps), they can lead to serious damage to these core components. The existing circulating pond system cannot detect whether the pipeline is blocked or not in a pipeline system in real time.

In addition, slow type leaks can occur in the piping of the flow cell system for various reasons. However, in existing flow cell systems, the presence of a leak in the piping system may not be detected until the test is completed. For example, the test duration of a certain client is 90 days, and the sampling and detecting time points are 30 days, 60 days and 90 days. If the leakage phenomenon occurs, no leakage detection device exists, and the client can only find data abnormality in sampling detection for 30 days. Delay time and influence progress.

Therefore, a flow cell system capable of detecting a clogged pipe is desired.

SUMMERY OF THE UTILITY MODEL

In view of the above, in order to solve the above problems, an object of the present invention is to provide a flow cell system including:

the metering pump is used for providing power for the flow cell system;

the flow cell is used for dissolving out the working medium;

the collecting tank is communicated with the flow cell through an open-loop sampling pipeline to collect working media in the flow cell, and a sampling closed-loop open-loop valve is arranged on the open-loop sampling pipeline; and

a detection system comprising a second gravity detection system disposed at the bottom of the trough to detect a rate of weight change of the trough and configured to issue an alarm when the rate of weight change is below a predetermined threshold.

Preferably, the flow cell system further comprises a buffer bottle for stabilizing the flow velocity of the working medium, and the buffer bottle is communicated with the flow cell through a flow cell liquid outlet pipeline provided with a liquid outlet closed-loop open-loop valve.

Preferably, the flow cell system further comprises a medium container for containing the working medium, the buffer bottle is communicated with the metering pump through a valve pump pipeline provided with an open-closed loop liquid inlet selection valve, the open-closed loop liquid inlet selection valve is provided with a first working position and a second working position, and when the open-closed loop liquid inlet selection valve is located at the first working position, an outlet end of the open-closed loop liquid inlet selection valve is communicated with an inlet end of the metering pump; when the opening-closing ring liquid inlet selector valve is positioned at a second working position, the inlet end of the metering pump is communicated with the medium container so as to inject the working medium into the flow cell system.

Preferably, the second gravity sensing system includes at least 2 gravity sensors and at least 2 height adjusters distributed at a bottom periphery of the buffer bottle.

Preferably, the gravity sensors and the height adjusters are evenly distributed in the circumferential direction of the collecting trough and are arranged at intervals to each other.

Preferably, a level is arranged on the side wall of the collecting tank.

Preferably, the flow cell system further comprises a heat exchange system for heating a working medium in the flow cell system, the heat exchange system is respectively connected with the flow cell and the metering pump, the flow cell comprises an outer cylinder, an inner cylinder and a circulating device, and the inner cylinder is sleeved in the outer cylinder and is respectively communicated with the buffer bottle and the metering pump; an inner cavity for containing liquid for maintaining the temperature of the working medium is formed between the outer cylinder and the inner cylinder; the circulation device is disposed outside the outer cylinder and in fluid communication with the inner cavity, and is for maintaining a temperature of the liquid.

Preferably, the flow cell further comprises a lifting clamping mechanism capable of adjusting the inner cylinder or the outer cylinder, and the lifting clamping mechanism is capable of adjusting the corresponding inner cylinder or the corresponding outer cylinder, so that the inner cylinder and the outer cylinder are disengaged from each other.

Preferably, the metering pump is a ceramic pump with adjustable working pressure, and the working pressure of the ceramic pump is set based on the detection result of the second gravity detection system.

Preferably, the predetermined threshold value is not greater than 5% of the rated flow rate of the metering pump.

Due to the adoption of the technical scheme, compared with the prior art, the utility model has the following positive effects: by applying the utility model, a gravity detection system is provided under specific parts of the flow-through basin system (buffer bottles, collection tanks). By means of the real-time detection function of the gravity detection system, the flow cell system can detect whether leakage occurs in the flow cell system in real time. In addition, the second gravity detection system in the flow-through cell system can also be used as a calibration system for calibrating the operating pressure of the metering pump.

Drawings

FIG. 1 is an overall schematic view of a flow cell system of the present invention;

description of reference numerals:

1. a flow-through cell system; 01. a medium supply device; 02. opening a closed loop liquid inlet selection valve; 03. a valve pump line; 04. a metering pump; 05. opening and closing the ring liquid outlet pipeline; 06. a water bath; 061. heating a tube; 07. a flow-through cell; 08. a liquid outlet pipeline of the flow cell; 09. a liquid outlet closed-loop ring opening valve; 11. a buffer bottle; 12. a closed loop liquid inlet pipeline; 13. a closed loop sampling pipeline; 14. sampling, pumping in and out of the pump valve; 15. an injection pump; 16. an open-loop sampling pipeline; 17. a sampling closed-loop open-loop valve; 18. injecting a sampling pipeline; 19. a sampling waste liquid valve; 20. A first sampling needle; 21. a waste liquid tank; 23. collecting tank; 24. a closed loop fluid infusion pipeline; 25. returning liquid; 26. a second sampling needle; 011. a solvent selector; 012. a first valve block; 013. a media container; 27. Five pipeline adapter plates; 28. a pressure sensor; 29. a temperature sensor; 071. an outer cylinder; 072. an inner cylinder; 30. a heat exchange system; 41. 51, a gravity sensor; 42. and 52, a height adjuster.

Detailed Description

The utility model is further described with reference to the following drawings and specific examples, which are not intended to be limiting.

As shown in fig. 1, a flow cell 07 system of a preferred embodiment is shown, where the flow cell 07 system includes a metering pump 04, a flow cell 07, a collection tank 23, a detection system, and the like. Wherein, the metering pump 04 is used for providing power for the flow cell 07 system. To ensure that the flow cell 07 system according to the present disclosure can be adapted to detect various chemical samples, in the present disclosure, the metering pump 04 employs a ceramic pump having corrosion-resistant and wear-resistant properties.

The flow cell 07 is used for dissolving out the working medium. In the present disclosure, flow cell 07 includes an outer barrel 071, an inner barrel 072, and a circulation device. Wherein, the inner cylinder 072 is sleeved in the outer cylinder 071 and is respectively communicated with the buffer bottle 11 and the heat exchange system 30. An inner cavity for containing liquid for maintaining the temperature of the working medium is formed between the outer cylinder body 071 and the inner cylinder body 072. A circulation device (not shown) is disposed outside of the outer barrel 071 and in fluid communication with the lumen and is used to maintain the temperature of the liquid. The liquid outlet pipeline 05 of the open-close ring passes through the outer cylinder 071 and is connected with the bottom of the inner cylinder 072.

The circulating device can be a conventional heat exchange device such as a heat exchanger.

Typically, the liquid within the lumen is maintained within the range of 36.8 deg.C-38.5 deg.C to provide a body temperature environment. Preferably, the liquid within the lumen is maintained at 37 ℃.

Alternatively, flow cell 07 may be provided with a lifting clamp mechanism (not shown) that can adjust inner barrel 072 or outer barrel 071. The holding relationship between inner barrel 072 or outer barrel 071 is determined by a lifting clamping mechanism. In certain cases, the lifting and clamping mechanism can adjust the corresponding inner cylinder 072 or outer cylinder 071 such that inner cylinder 072 and outer cylinder 071 disengage from each other. The lifting clamping mechanism is, for example, a piston-type clamping mechanism, in which a piston can be fixed on the inner cylinder. It can be understood that the lifting clamping mechanism can also be composed of a holding clamping jaw for clamping the outer cylinder and a supporting column for fixing the inner cylinder.

For the detection system in the flow cell 07 system, it includes a second gravity detection system (including a gravity sensor 51, a height adjuster 52, etc.). A second gravity detection system is provided at the bottom of the collection gutter 23 to detect the rate of weight change of the collection gutter 23 and is configured to be able to issue an alarm when the rate of weight change is below a predetermined threshold.

According to the above flow cell 07 system, the metering pump 04, the flow cell 07, the buffer bottle 11, and the collecting tank 23 are connected in sequence through a pipeline to form an open loop system. When the open loop system is started, the working medium flows along the open loop pipeline system of the metering pump 04, the flow cell 07, the buffer bottle 11, the metering pump 04 and the collecting tank 23. When a leakage condition occurs at any position in the pipeline system, the second gravity detection system can detect that the weight of the collecting tank 23 is increased and reduced, so that a tester is reminded to interrupt the test and further confirm the leakage position in the pipeline system. When the closed loop liquid inlet pipeline 12 in the pipeline system is blocked or the metering pump 04 is in fault, the numerical value detected by the second gravity detection system cannot be changed, so that a tester is reminded of the situation that the metering pump 04 is in fault or the blockage occurs.

Besides, when the weight increasing rate of the collecting groove 23 is in a stable state in a relatively long time of the pipeline system, the working state of the metering pump 04 is indicated to be good, and all the sections of the pipeline system of the flow-through pond system are in a normal flow-through state. At this time, the actual working pressure and working flow rate of the metering pump 04 can be calculated by measuring the weight increase rate value detected by the second gravity detection system. The second gravity detection system can therefore simultaneously be used for calibrating the operating pressure of the metering pump 04. Under the condition that the working pressure of the metering pump 04 in the current state does not meet the requirement, the staff can adjust the motor of the metering pump 04 and verify the actual working flow of the metering pump 04 through the second gravity detection system.

With continued reference to fig. 1, optionally, the flow cell 07 system further comprises a buffer bottle 11 for stabilizing the flow rate of the working medium, wherein the buffer bottle 11 and the flow cell 07 are communicated through a flow cell outlet pipe 08 provided with an outlet closed-loop open-loop valve 09. According to the present disclosure, the buffer vessel 11 is set to have any volume in the range of 100ML-2000ML, which may be set according to the flow rate of the system, etc. The inlet end of the buffer bottle 11 is communicated with the outlet end of the flow cell 07 (inner cylinder 072) through a flow cell liquid outlet pipeline 08; the outlet end of the buffer bottle 11 is communicated with a collecting tank 23 through a closed-loop sampling pipeline 13. Alternatively, flow cell outlet conduit 08 may be provided with an outlet closed loop open loop valve 09 having two operating positions. When the liquid outlet closed-loop open-loop valve 09 is in one working position, the buffer bottle 11 and the flow cell 07 pass through. In the other operating position, in communication with a sampling closed-loop open-loop valve 17 (described below). The outlet end of the buffer bottle 11 is communicated with the metering pump 04 through a closed-loop liquid inlet pipeline 12.

A medium container 013 for accommodating the working medium can also be provided in the flow cell 07 system. The buffer bottle 11 is communicated with the metering pump 04 through a valve pump pipeline 03 provided with an open-closed loop liquid inlet selector valve 02, the open-closed loop liquid inlet selector valve 02 is provided with a first working position and a second working position, and when the open-closed loop liquid inlet selector valve 02 is located at the first working position, the outlet end of the open-closed loop liquid inlet selector valve 02 is communicated with the inlet end of the metering pump 04; when the open-close loop liquid inlet selection valve 02 is in the second working position, the inlet end of the metering pump 04 is communicated with a medium container 013, so as to inject the working medium into the flow cell 07 system.

With continued reference to fig. 1, in the flow cell 07 system of the present disclosure, a heat exchange system 30 for heating the working medium within the flow cell 07 system may also be disposed between the metering pump 04 and the flow cell 07. The metering pump 04 is communicated with the heat exchange system 30 through an open-close ring liquid outlet pipeline 05. In the present disclosure, referring to fig. 1, the heat exchange system 30 includes a water bath 06, a heating pipe 061, and other conventional devices, which will not be described in detail herein. The inlet end of the heat exchange system 30 is communicated with the outlet end of the metering pump 04 through an opening-closing ring liquid outlet pipeline 05.

The flow cell 07 system is optionally also provided with a closed loop system. Specifically, an open-close loop liquid inlet selector valve 02 is arranged on a closed-loop liquid inlet pipeline 12 between the buffer bottle 11 and the metering pump 04. The open-close loop liquid inlet selection valve 02 has a first working position and a second working position. When the opening-closing ring liquid inlet selector valve 02 is at the first working position, the outlet end of the opening-closing ring liquid inlet selector valve 02 is communicated with the inlet end of the metering pump 04, and a working medium flows along a closed-loop pipeline system of the metering pump 04, a heating system, the flow cell 07, the buffer bottle 11 and the metering pump 04; when the open-close ring liquid inlet selector valve 02 is in the second working position, the inlet end of the metering pump 04 is communicated with a medium container 013 for containing the working medium, so as to inject the working medium into the flow cell 07 system.

For the second gravity detection system herein, it preferably comprises at least 2 gravity sensors 51 and at least 2 height adjusters 51 arranged at the periphery of the bottom of the buffer flask. At this time, the above-described weight change rate is an average value of the detection values of these 2 gravity sensors 51. By providing more gravity sensors, the gravity sensor 51 of the present disclosure can obtain a more accurate detection result. In particular, when used to correct the working flow of the metering pump 04, the gravity sensor 51 may be provided more, for example 3, 4 or more. The height adjuster 52 is favorable for adjusting the buffer bottle to the horizontal position, so that different impact actions of the continuously injected working medium on the gravity sensors 51 at different positions are avoided, and obvious numerical value deviation occurs on different gravity sensors 51, so that detection result distortion is caused.

These gravity sensors 51 are preferably arranged uniformly at different circumferential positions of the collection trough 23, in order to obtain data reflecting the true rate of change of the weight of the collection trough 23 after a weighted evaluation of the detection values of these gravity sensors.

These height adjusters 51 are also preferably arranged uniformly at different circumferential positions of the collecting gutter 23, in order to make it easier to level the collecting gutter 23.

The gravity sensors 51 and the height adjusters 52 are preferably distributed uniformly and spaced apart from one another in the circumferential direction of the collecting trough 23.

In the flow cell 07 system of the present disclosure, a magnetic stirrer is provided at the bottom center of the buffer bottle 11, which is used to ensure that the liquid in the buffer bottle 11 is uniformly mixed. In this case, the first gravity detecting system avoids the bottom center position of the buffer bottle 11. For example, the first gravity sensing system is composed of at least 1 gravity sensor 41 and at least 2 height adjusters 42 distributed on the bottom periphery of the buffer bottle 11. At least 1 gravity sensor 41 and at least 2 height adjusters 42 are arranged at intervals from each other and are uniformly distributed in the circumferential direction of the buffer bottle 11. A level is optionally provided on the side wall of the buffer bottle 11. In use, the gravity sensor 41 and the height adjuster 42 may be arranged at various positions of the buffer bottle 11, and then the height adjuster 42 may be adjusted so that the buffer bottle 11 is stably placed. The tester can confirm whether the buffer bottle 11 is in a steady state by checking the level meter.

Furthermore, it comprises a first gravity detection unit located at the bottom of the buffer bottle 11 for detecting the weight of the buffer bottle 11 loaded with the working medium. The first gravity detecting unit is configured to issue a leakage alarm when the first gravity detecting unit detects that the magnitude of change in the weight exceeds a predetermined threshold. For the predetermined threshold, this can be obtained by testing according to the flow rate of the working medium in the system, the weight of the buffer bottle 11, and the working medium contained in the buffer bottle 11 under the test condition.

When the closed loop system is opened, the working medium flows along the closed loop pipeline system of the metering pump 04, the heat exchange system 30, the flow cell 07, the buffer bottle 11 and the metering pump 04. When the leakage condition occurs at any position in the pipeline system, the first gravity detection system can detect that the weight of the buffer bottle 11 is gradually reduced, so that a tester is reminded to interrupt the test and further confirm the leakage position in the pipeline system. And when the closed loop liquid inlet pipeline 12 in the pipeline system is blocked, the metering pump 04 cannot perform pumping operation, and the numerical value detected by the first gravity detection system cannot be changed, so that a tester is reminded of the blocking condition.

Preferably, an open-close ring liquid inlet selector valve 02 between the buffer bottle 11 and the metering pump 04 can be arranged on the flow cell 07 system. The open-close loop liquid inlet selector valve 02 is provided with a first working position and a second working position, and when the open-close loop liquid inlet selector valve 02 is positioned at the first working position, the outlet end of the open-close loop liquid inlet selector valve 02 is communicated with the inlet end of the metering pump 04; when the open-close ring liquid inlet selector valve 02 is in the second working position, the inlet end of the metering pump 04 is communicated with a medium container 013 for containing a working medium so as to inject the working medium into the flow cell 07 system. Through opening closed loop feed liquor selection valve 02, the tester can select when to pour into working medium into the pipeline, has avoided the dismantlement work of system pipeline that detection jam, test jam must carry out among the prior art.

Alternatively, the flow cell 07 system may be provided with a solvent selector 011 having a plurality of channels and a plurality of medium containers 013 for accommodating different working media, respectively. The solvent selector 011 is connected with the outlet end of each medium container 013 and the inlet end of the opening-closing ring liquid inlet selector valve 02 respectively. Menstruum selector 011 is configured to alternatively select a media reservoir 013 in communication with the open closed loop feed selector valve 02. Solvent selector 011 can be considered a multi-position working valve with multiple passages. The flow cell system 1 of the present disclosure can be applied to dissolution detection of different working media by the solvent selector 011 and the respective different medium containers 013. Media container 013 and vehicle selector 011011 make up media supply 01.

With continued reference to fig. 1, the flow-through cell 07 system also includes a holding tank 23, a second gravity detection system, and a sample in pump out pump valve 14. Specifically, the collecting tank 23 is communicated with the buffer bottle 11 through the closed-loop sampling pipeline 13, the second gravity detection system is arranged at the bottom of the collecting tank 23 for detecting the weight of the collecting tank 23, and the sampling pump-in and pump-out valve 14 is arranged on the closed-loop sampling pipeline 13.

When the open-close loop liquid inlet selector valve 02 is at the second working position, the sampling pump-in and pump-out pump valve 14 opens the closed-loop sampling pipeline 13. In this case, the flow path of the working medium is the medium container 013, the metering pump 04, the heat exchange system 30, the flow cell 07, the buffer bottle 11, and the collecting tank 23. After the metering pump 04 is started, the working medium pumped by the metering pump 04 will eventually flow to the collecting tank 23. The second gravity detection system detects the weight change of the collecting tank 23 in real time in the process, and then the pumping flow and the actual working pressure of the metering pump 04 can be obtained. In view of the above, the second gravity detecting system can play the effect of demarcation measuring pump 04 operating pressure. When the working pressure of the metering pump 04 does not meet the requirement, the working motor of the metering pump 04 can be adjusted.

In addition, when the metering pump 04 is blocked, the collecting groove 23 is difficult to collect the working medium with a stable flow rate after the metering pump 04 works. Accordingly, the second gravity detection system can also serve the purpose of detecting whether the metering pump 04 is blocked or not.

As mentioned above, according to a preferred embodiment of the present disclosure, the flow cell 07 is provided with a lifting and clamping mechanism. When the open-close ring liquid inlet selector valve 02 is at the second working position, the sampling inlet pump outlet pump valve 14 opens the closed-loop liquid taking pipeline. The lifting clamping mechanism now adjusts the corresponding inner barrel 072 or outer barrel 071 so that the inner barrel 072 and outer barrel 071 disengage from each other. And then the calibration work of the working pressure of the metering pump 04 is carried out. By the configuration, the flow rate of the working medium in the system can be prevented from being influenced by the liquid in the inner cavity of the outer cylinder 071, and the stability of the calibration operation of the working pressure of the metering pump 04 is further improved.

According to the present disclosure, the detection system is optionally provided with a first gravity detection unit detecting the weight of the buffer bottle 11 loaded with the working medium at the bottom of the buffer bottle 11. The first gravity detection unit is configured to issue a leak alarm when the first gravity detection unit detects that the magnitude of change in weight exceeds a predetermined threshold. For the predetermined threshold, since the first gravity detection system at the bottom of the buffer bottle 11 is used for detecting the state of the closed loop system which does not exchange the working medium with the outside, and the detection data of the first gravity detection system is determined by the working pressure of the metering pump 04, the predetermined threshold of the present disclosure can be obtained by testing according to the flow rate of the working medium in the system, the weight of the buffer bottle 11, and the working medium contained in the buffer bottle 11 which meets the test conditions.

Optionally, a temperature sensor 29 may be disposed on the open-close ring liquid outlet line 05, so as to detect the temperature of the working medium in the open-close ring liquid outlet line 05 in real time.

In the above description, two parallel working medium flow paths (the closed-loop liquid inlet pipeline 12 and the closed-loop sampling pipeline 13) are introduced from the buffer bottle 11, and in order to realize more functions, the flow cell 07 system according to the present application is further provided with more other flow channels.

Specifically, the buffer bottle 11 may further be provided with a closed-loop fluid infusion line 24, and a fluid return strip 25 and a second sampling needle 26 may be disposed on the closed-loop fluid infusion line. One end of the closed-loop fluid infusion pipeline 24 is connected with the inside of the buffer bottle 1111, the other end of the closed-loop fluid infusion pipeline is connected with the fluid return strip 25, and the second sampling needle 26 is operatively connected with the fluid return strip 25.

Besides, the sampling closed-loop open-loop valve 17 has two working states, in one working state, as described above, it is communicated with the outlet closed-loop open-loop valve 09 to guide the working medium in the flow-through cell 07 to the collecting tank 23; in another operating state, it communicates with the sample inlet pump outlet pump valve 14 on the closed-loop sample line 13 to direct the buffer reservoir working medium to the collection tank 23.

The sampling pump-in and pump-out valve 14, as a control valve on the closed-loop sampling line 13, also has two operating states, one of which communicates with the downstream sampling waste liquid valve 19 as described above, the sampling waste liquid valve 19 discharging the working medium to the waste liquid tank 21 through the first sampling needle 20 in one operating state and to the collection tank 23 in the other operating state; in another operating state, the sample pump-in and pump-out valve 14 is in communication with the syringe pump 15. The infusion pump 15 can conduct the working medium in a specific state.

While the utility model has been described with reference to a preferred embodiment, it will be understood by those skilled in the art that various changes in form and detail may be made therein without departing from the spirit and scope of the utility model.

Claims

1. A flow cell system, comprising:

the metering pump is used for providing power for the flow cell system;

the flow cell is used for dissolving out the working medium of the flow cell system;

a detection system comprising a second gravity detection system disposed at a bottom of the trough to detect a rate of weight change of the trough and configured to issue an alarm when the rate of weight change is below a predetermined threshold.

2. The flow cell system of claim 1, further comprising a buffer bottle for stabilizing a flow rate of the working medium, wherein the buffer bottle and the flow cell are in communication via a flow cell outlet line provided with a closed outlet ring opening valve.

3. The flow cell system of claim 2, further comprising a media container for containing the working media, wherein the buffer bottle is in communication with the metering pump via a valve pump line having an open-closed loop feed selection valve, the open-closed loop feed selection valve having a first operating position and a second operating position, and wherein when the open-closed loop feed selection valve is in the first operating position, an outlet end of the open-closed loop feed selection valve is in communication with an inlet end of the metering pump; when the opening-closing ring liquid inlet selector valve is positioned at a second working position, the inlet end of the metering pump is communicated with the medium container so as to inject the working medium into the flow cell system.

4. A flow-through pond system according to claim 2 or 3, wherein the second gravity detection system comprises at least 2 gravity sensors and at least 2 height adjusters distributed around the bottom periphery of the buffer vessel, the rate of weight change being an average of the values detected by the at least 2 gravity sensors.

5. A flow-through basin system according to claim 4, wherein the gravity sensors and the height adjusters are evenly distributed in the circumferential direction of the collecting trough and are arranged at a distance from each other.

6. A flow-through cell system according to claim 4, wherein the collection trough is provided with level means on its side walls.

7. A flow-through basin system according to claim 2, further comprising a heat exchange system for heating a working medium in the flow-through basin system, which heat exchange system connects the flow-through basin and the metering pump, respectively, and,

the circulation pool comprises an outer cylinder body, an inner cylinder body and a circulating device, wherein the inner cylinder body is sleeved in the outer cylinder body and is respectively communicated with the buffer bottle and the metering pump; an inner cavity for containing liquid for maintaining the temperature of the working medium is formed between the outer cylinder and the inner cylinder; the circulation device is disposed outside the outer cylinder and in fluid communication with an inner cavity between the cylinder and the inner cylinder, and is used to maintain the temperature of the liquid.

8. The flow cell system of claim 7, further comprising a lifting clamping mechanism capable of adjusting the inner or outer cylinder, the lifting clamping mechanism capable of adjusting the corresponding inner or outer cylinder such that the inner and outer cylinders are disengaged from each other.

9. The flow cell system of claim 8, wherein the metering pump is a ceramic pump having an adjustable working pressure, and the working pressure of the ceramic pump is set based on the detection result of the second gravity detection system.

10. The flow cell system of claim 1, wherein the predetermined threshold is no greater than 5% of a rated flow rate of the metering pump.