CN216926680U

CN216926680U - Pipeline system of detection analyzer

Info

Publication number: CN216926680U
Application number: CN202220064653.6U
Authority: CN
Inventors: 黄郁荣; 赖远强; 聂伟华; 钟奇昌
Original assignee: Guangzhou Wondfo Biotech Co Ltd
Current assignee: Guangzhou Wondfo Biotech Co Ltd
Priority date: 2022-01-11
Filing date: 2022-01-11
Publication date: 2022-07-08
Anticipated expiration: 2032-01-11

Abstract

The utility model belongs to the field of detection instruments, and discloses a detection analyzer pipeline system which comprises a waste liquid pipeline, a reference liquid pipeline, a sample liquid pipeline, a detection card and at least two delivery pumps, wherein a waste liquid channel, a reference liquid channel and a sample liquid channel are arranged in the detection card, the waste liquid pipeline, the reference liquid pipeline and the sample liquid pipeline are respectively communicated with the waste liquid channel, the reference liquid channel and the sample liquid channel, and the waste liquid pipeline and the reference liquid pipeline are respectively provided with the delivery pumps. The delivery of the reference fluid as well as the sample fluid or other reagents can be conveniently controlled.

Description

Pipeline system of detection analyzer

Technical Field

The utility model belongs to the field of detection instruments, and particularly relates to a pipeline system of a detection analyzer.

Background

The device is used in medical equipment for detecting the content of oxygen, carbon dioxide and other gases in blood of critical patients, the pH value of the blood and relevant indexes, such as a blood gas analyzer biochemical instrument of an in vitro diagnostic instrument. The ion concentration and gas in the sample are detected using the electrodes as sensors. Wherein blood gas analyzer is when using, carries reference liquid, reagent or air and carries the waste liquid to go out through a pump body, but reference liquid pipe, waste liquid pipe can only two pipes start the infusion simultaneously and stop the infusion simultaneously, can not start alone or stop, owing to adopt same pump body moreover, so all have a higher requirement to the material and the thickness etc. of reference liquid pipe and waste liquid pipe.

SUMMERY OF THE UTILITY MODEL

The present invention is directed to overcoming the disadvantages of the prior art and providing a detection analyzer tubing system that facilitates controlled delivery of reference fluids as well as sample fluids or other reagents.

The technical scheme is as follows:

the pipeline system of the detection analyzer comprises a waste liquid pipeline, a reference liquid pipeline, a sample liquid pipeline, a detection card and at least two delivery pumps, wherein a waste liquid channel, a reference liquid channel and a sample liquid channel are arranged in the detection card, the waste liquid pipeline, the reference liquid pipeline and the sample liquid pipeline are respectively communicated with the waste liquid channel, the reference liquid channel and the sample liquid channel, and the delivery pumps are arranged on the waste liquid pipeline and the reference liquid pipeline.

In one embodiment, the delivery pump is a peristaltic pump, and the waste liquid line, the reference liquid line and the sample liquid line are flexible pipes.

In one embodiment, a one-way valve is installed in the waste liquid pipeline.

In one embodiment, the analytical test meter tubing system further comprises a sample transporter, a reagent transporter, and a switch coupled to the sample fluid line, wherein the sample transporter and the reagent transporter are both coupled to the switch at their inlets.

In one embodiment, the switch comprises at least a liquid output port, a sample input port and a reagent input port, the output ports of the sample transporter and the reagent transporter are respectively communicated with the sample input port and the reagent input port, the liquid output port is connected with the sample liquid pipeline, and the switch controls the liquid output port to be communicated with only the sample input port or only the reagent input port.

In one embodiment, the reagent conveyor comprises a plurality of reagents, each reagent being discharged through a reagent port, a different one of the reagent ports being selectively in communication with the output port of the reagent conveyor.

In one embodiment, the detection analyzer piping system further comprises a reference solution container and a waste collector, the reference solution container being in communication with the reference solution conduit, and the waste conduit being in communication with the waste collector.

In one embodiment, the sample fluid channel and the reference fluid channel each have a cross-section greater than the cross-section of the reference fluid channel at the intersection of the sample fluid channel and the reference fluid channel.

In one embodiment, the intersection of the sample fluid channel and the reference fluid channel forms an angle θ between the fluid flow direction of the sample fluid channel and the fluid flow direction of the reference fluid channel, and the angle θ is less than 90 °.

In one embodiment, the waste liquid channel, the reference liquid channel and the sample liquid channel are all provided with connecting needle tubes, the waste liquid channel, the reference liquid channel and the sample liquid channel are all provided with step parts, the step parts comprise wide parts and narrow parts, the connecting needle tubes are inserted into the wide parts, and the inner diameter of the connecting needle tubes is more than 0.8 times of the inner diameter of the narrow parts.

The technical scheme provided by the utility model has the following advantages and effects:

the detection analyzer is at the during operation that begins, need carry the sample, two delivery pumps all open this moment, let in the sample on the sample liquid pipeline, under the delivery pump on waste liquid pipeline, flow in to the sample liquid passageway of detection card, and in the reference liquid passageway of reference liquid entering detection card is carried through the delivery pump that is located on the reference liquid pipeline to the reference liquid, at last under the effect of the delivery pump on waste liquid pipeline, sample and reference liquid all enter into waste liquid pipeline through waste liquid passageway output. When the reagent is required to be input, the sample liquid pipeline has the functions of conveying the sample and the reagent, so that the reagent is input into the sample liquid channel of the detection card through the sample liquid pipeline, and meanwhile, the reference liquid can also be input into the reference liquid channel through the action of a conveying pump positioned on the reference liquid pipeline. The design of the double delivery pumps is adopted, the flow rate of the reference liquid and the flow rate of the sample can be independently controlled, namely the flow rate of the liquid can be controlled through the speed of the delivery pumps, so that the aim of saving the liquid is achieved, and the working requirements on the waste liquid pipeline and the reference liquid pipeline are not high. Moreover, when the sample liquid channel and the waste liquid channel of the detection card need to be cleaned, the conveying pump on the waste liquid pipeline can be started only, and the purpose of saving the reference liquid is achieved.

Drawings

The accompanying drawings, which are incorporated in and constitute a part of this specification, illustrate embodiments of the utility model and, together with the description, serve to explain the principles and effects of the utility model.

Unless otherwise specified or defined, the same reference numerals in different figures refer to the same or similar features, and different reference numerals may be used for the same or similar features.

FIG. 1 is a schematic diagram of a reference solution and a sample in transport according to an embodiment of the present invention;

FIG. 2 is a schematic diagram of the structure of the reference solution and reagent delivery according to an embodiment of the present invention;

FIG. 3 is an enlarged structural view of the structure at A in FIG. 1 according to an embodiment of the present invention;

FIG. 4 is an enlarged structural view of the structure at B in FIG. 2 according to an embodiment of the present invention;

FIG. 5 is a schematic diagram of an internal structure of a test card according to an embodiment of the present invention;

fig. 6 is an enlarged structural diagram of the structure at C in fig. 5 according to the embodiment of the present invention.

Description of reference numerals:

10. a waste liquid line; 11. a one-way valve; 20. a reference liquid line; 30. a sample liquid line; 40. detecting the card; 41. a waste liquid channel; 42. a reference liquid channel; 43. a sample fluid channel; 44. connecting a needle tube; 45. a step portion; 451. a wide part; 452. a narrow part; 50. a delivery pump; 60. a sample conveyor; 70. a reagent conveyor; 71. a reagent port; 80. a switch; 81. a liquid outlet; 82. a sample input port; 83. a reagent input port; 84. a sampling needle tube; 91. a reference solution container; 92. a waste liquid container.

Detailed Description

In order to facilitate an understanding of the utility model, specific embodiments thereof will be described in more detail below with reference to the accompanying drawings.

Unless specifically stated or otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. In the case of combining the technical solutions of the present invention in a realistic scenario, all technical and scientific terms used herein may also have meanings corresponding to the purpose of achieving the technical solutions of the present invention.

As used herein, unless otherwise specified or defined, "first" and "second" … are used merely for name differentiation and do not denote any particular quantity or order.

As used herein, the term "and/or" includes any and all combinations of one or more of the associated listed items, unless specified or otherwise defined.

It will be understood that when an element is referred to as being "secured to" another element, it can be directly secured to the other element or intervening elements may also be present; when an element is referred to as being "connected" to another element, it can be directly connected to the other element or intervening elements may also be present; when an element is referred to as being "mounted on" another element, it can be directly on the other element or intervening elements may also be present. When an element is referred to as being "on" another element, it can be directly on the other element or intervening elements may also be present.

As shown in fig. 1, 2 and 5, the pipeline system of the detection analyzer includes a waste liquid pipeline 10, a reference liquid pipeline 20, a sample liquid pipeline 30, a detection card 40 and at least two delivery pumps 50, wherein a waste liquid channel 41, a reference liquid channel 42 and a sample liquid channel 43 are arranged inside the detection card 40, the waste liquid pipeline 10, the reference liquid pipeline 20 and the sample liquid pipeline 30 are respectively communicated with the waste liquid channel 41, the reference liquid channel 42 and the sample liquid channel 43, and the delivery pumps 50 are respectively installed on the waste liquid pipeline 10 and the reference liquid pipeline 20.

When the detection analyzer starts to work, a sample needs to be conveyed, at this time, both the two conveying pumps 50 are started, the sample is introduced into the sample liquid pipeline 30, the sample liquid flows into the sample liquid channel 43 of the detection card 40 under the conveying of the conveying pump 50 on the waste liquid pipeline 10, the reference liquid is conveyed into the reference liquid channel 42 of the detection card 40 through the conveying pump 50 on the reference liquid pipeline 20, and finally, under the action of the conveying pump 50 on the waste liquid pipeline 10, the sample and the reference liquid are both output through the waste liquid channel 41 and enter the waste liquid pipeline 10. When the reagent needs to be input, the sample liquid pipeline 30 has the functions of conveying the sample and the reagent, so that the reagent is input into the sample liquid channel 43 of the detection card 40 through the sample liquid pipeline 30, and meanwhile, the reference liquid can also be input into the reference liquid channel 42 through the function of the conveying pump 50 positioned on the reference liquid pipeline 20. By adopting the design of the double delivery pumps 50, the flow rate of the reference liquid and the flow rate of the sample can be independently controlled, namely the flow rate of the liquid can be controlled by the speed of the delivery pump 50, so that the aim of saving the liquid is achieved, and the working requirements on the waste liquid pipeline 10 and the reference liquid pipeline 20 are not high. Furthermore, when the sample liquid channel 43 and the waste liquid channel 41 of the detection card 40 need to be cleaned, only the transfer pump 50 on the waste liquid pipeline 10 can be started, so as to achieve the purpose of saving the reference liquid.

Moreover, the dual feed pump 50 aspect of the present embodiment also serves to prevent waste fluid from contaminating the reference fluid channel 42, as opposed to the single feed pump 50 prior art. When a single delivery pump 50 is used, once the delivery process of the delivery pump 50 is stopped, the waste liquid and the reference liquid cannot flow, and the liquid has a diffusion tendency, so that the waste liquid is easy to diffuse into the reference liquid channel 42, further polluting the reference liquid channel 42 and influencing subsequent detection. The scheme just solves the problem, and because two delivery pumps 50 are adopted, even if one of the two delivery pumps stops, the other delivery pump can work normally, and the probability that the two delivery pumps 50 stop at the same time is very low. In the first case, the delivery pump 50 on the waste liquid pipeline 10 is stopped, and the delivery pump 50 on the reference liquid pipeline 20 continues to deliver the reference liquid, so that the waste liquid cannot enter the reference liquid channel 42 under the condition of continuous delivery of the reference liquid; in the second situation, the delivery pump 50 on the reference liquid line 20 is stopped to deliver the reference liquid, and the delivery pump 50 on the waste liquid line 10 continues to work, so that the waste liquid is discharged outwards under the action of the delivery pump 50 on the waste liquid line 10, and the waste liquid is prevented from entering the reference liquid channel 42.

The conveying pump 50 adopts a peristaltic pump, and the waste liquid pipeline 10, the reference liquid pipeline 20 and the sample liquid pipeline 30 all adopt flexible pipelines. Because the flexible pipeline is installed in a shell, the flexible pipeline can be conveniently stored, wherein the peristaltic pump is matched with the flexible pipeline to provide power for liquid in the flexible pipeline. The arrows in fig. 1 and 2 indicate the direction of flow of the liquid, and the direction of rotation of the peristaltic pump.

As shown in fig. 1 and 2, a check valve 11 is installed in the waste liquid line 10. In order to prevent the waste liquid from flowing backwards, a one-way valve 11 is arranged to control the waste liquid to be discharged only along the waste liquid pipeline 10.

As shown in fig. 1 and 2, the pipeline system of the detection analyzer further includes a sample conveyer 60, a reagent conveyer 70, and a switch 80, wherein the switch 80 is connected to the sample liquid pipeline 30, and the inlets of the sample conveyer 60 and the reagent conveyer 70 are connected to the switch 80. The switch 80 controls the sample conveyor 60 or the reagent conveyor 70 to communicate with the sample liquid pipeline 30, so that the sample or the reagent can be introduced separately.

As shown in fig. 3 and 4, the switch 80 includes at least a liquid output port 81, a sample input port 82, and a reagent input port 83, the output ports of the sample transporter 60 and the reagent transporter 70 are respectively communicated with the sample input port 82 and the reagent input port 83, the liquid output port 81 is connected to the sample liquid line 30, and the switch 80 controls the liquid output port 81 to be communicated with only the sample input port 82 or only the reagent input port 83. When it is necessary to switch the input of the sample to the sample liquid line 30, the liquid output port 81 of the switch 80 is switched to communicate with the sample input port 82, and the sample transporter 60 outputs the sample at that time. When it is necessary to switch the input of the reagent to the sample liquid line 30, the liquid output port 81 of the switch 80 is switched to communicate with the sample input port 82, and the reagent transporter 70 outputs the reagent.

As shown in fig. 1 and 2, the reagent conveyor 70 includes a plurality of reagents, each reagent being discharged through one reagent port 71, and different reagent ports 71 selectively communicate with the output port of the reagent conveyor 70. Because there are many reagents, different reagents need to be switched and output continuously, and the purpose of controlling and outputting different reagents can be achieved by switching the communication between the different reagent ports 71 and the output ports of the conveyor.

The selection of the switch 80 can be varied, for example, a three-way valve design can be adopted, and the switch can be freely switched. In the present embodiment, as shown in fig. 3 and 4, the sample input or the reagent input is achieved by inserting the sampling needle 84 into the sample input port 82 or the reagent input port 83, and the sampling needle 84 is communicated with the sample liquid pipe 30.

The detection analyzer pipeline system further comprises a reference liquid container 91 and a waste liquid collector, wherein the reference liquid container 91 is communicated with the reference liquid pipeline 20, and the waste liquid pipeline 10 is communicated with the waste liquid collector. The reference solution container 91 is used for containing the reference solution, and the waste liquid collector is used for collecting waste liquid generated in the detection process.

As shown in fig. 5, at the intersection of the sample fluid channel 43 and the reference fluid channel 42, the sample fluid channel 43 and the waste fluid channel 41 each have a larger cross-section than the reference fluid channel 42. This design provides increased resistance to sample, reagent or waste fluid entering the reference channel 42, and thus makes entry more difficult.

As shown in fig. 5, at the intersection of the sample liquid channel 43 and the reference liquid channel 42, an included angle θ is formed between the liquid flow direction of the sample liquid channel 43 and the liquid flow direction of the reference liquid channel 42, and the included angle θ is smaller than 90 °. Because the sample or the reagent flows along the relatively unobstructed channel, and the included angle theta between the reference liquid channel 42 and the sample liquid channel 43 is smaller than 90 degrees, namely the design of an acute angle, the sample or the reagent has a tendency of backflow when flowing into the reference liquid channel 42, so that the sample or the reagent is difficult to enter the reference liquid channel 42, and the reference liquid channel 42 is prevented from being polluted.

As shown in fig. 5 and 6, a connection needle tube 44 is mounted on each of the waste liquid channel 41, the reference liquid channel 42, and the sample liquid channel 43, a step 45 is provided on each of the waste liquid channel 41, the reference liquid channel 42, and the sample liquid channel 43, the step 45 includes a wide portion 451 and a narrow portion 452, the connection needle tube 44 is inserted into the wide portion 451, and an inner diameter of the connection needle tube 44 is 0.8 times or more an inner diameter of the narrow portion 452. The connecting needle tube 44 can be conveniently installed. The inner diameter of connecting needle tube 44 is sized to be close to constriction 452, or larger than constriction 452, so that there is very little resistance to fluid flow. For more secure mounting, the portion of the connecting needle 44 is coated with an adhesive to provide a secure seal.

In this embodiment, the detection analyzer is a blood gas analyzer.

When the drawing description is quoted, the new characteristics are explained; in order to avoid that repeated reference to the drawings results in an insufficiently concise description, the drawings are not referred to one by one in the case of clear description of the already described features.

The above embodiments are provided to illustrate, reproduce and deduce the technical solutions of the present invention, and to fully describe the technical solutions, the objects and the effects of the present invention, so as to make the public more thoroughly and comprehensively understand the disclosure of the present invention, and not to limit the protection scope of the present invention.

The above examples are not intended to be exhaustive list based on the present invention, and there may be many other embodiments other than those listed. Any alterations and modifications without departing from the spirit of the utility model are within the scope of the utility model.

Claims

1. The pipeline system of the detection analyzer is characterized by comprising a waste liquid pipeline, a reference liquid pipeline, a sample liquid pipeline, a detection card and at least two delivery pumps, wherein a waste liquid channel, a reference liquid channel and a sample liquid channel are arranged in the detection card, the waste liquid pipeline, the reference liquid pipeline and the sample liquid pipeline are respectively communicated with the waste liquid channel, the reference liquid channel and the sample liquid channel, and the delivery pumps are arranged on the waste liquid pipeline and the reference liquid pipeline.

2. The analytical detection tubing set of claim 1, wherein the transfer pump is a peristaltic pump and the waste, reference and sample fluid lines are flexible tubing.

3. The analytical detection instrument tubing system of claim 1, wherein a one-way valve is installed in the waste fluid line.

4. The assay analyzer tubing system of any one of claims 1 to 3, further comprising a sample transporter, a reagent transporter, and a switch coupled to the sample fluid line, wherein the sample transporter and the reagent transporter are each coupled to the switch at their inlets.

5. The analytical test meter tubing set of claim 4, wherein the switch includes at least a liquid output port, a sample input port, and a reagent input port, the sample transporter and the reagent transporter having output ports in communication with the sample input port and the reagent input port, respectively, the liquid output port being connected to the sample liquid line, the switch controlling the liquid output port to communicate with only the sample input port or only the reagent input port.

6. The analytical test meter tubing set of claim 4, wherein the reagent delivery unit includes a plurality of reagents, each reagent being expelled through one of the reagent ports, a different one of the reagent ports being selectively in communication with an output port of the reagent delivery unit.

7. The detection analyzer piping system of any one of claims 1 to 3, further comprising a reference liquid container and a waste liquid collector, the reference liquid container communicating with the reference liquid piping, and the waste liquid piping communicating with the waste liquid collector.

8. The assay analyzer plumbing system of any one of claims 1 to 3, wherein the sample fluid channel and the reference fluid channel each have a cross-section larger than a cross-section of the reference fluid channel at an intersection of the sample fluid channel and the reference fluid channel.

9. The analytical detection meter tubing system of any of claims 1 to 3, wherein the intersection of the sample fluid channel and the reference fluid channel, the fluid flow direction of the sample fluid channel and the fluid flow direction of the reference fluid channel form an angle θ therebetween, the angle θ being less than 90 °.

10. The piping system of any one of claims 1 to 3, wherein a connecting needle tube is installed on each of the waste liquid channel, the reference liquid channel, and the sample liquid channel, and each of the waste liquid channel, the reference liquid channel, and the sample liquid channel has a stepped portion, the stepped portion includes a wide portion and a narrow portion, the connecting needle tube is inserted into the wide portion, and an inner diameter of the connecting needle tube is 0.8 times or more an inner diameter of the narrow portion.