CN216900573U - Card shell for immunochromatography test strip - Google Patents
Card shell for immunochromatography test strip Download PDFInfo
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- CN216900573U CN216900573U CN202220453588.6U CN202220453588U CN216900573U CN 216900573 U CN216900573 U CN 216900573U CN 202220453588 U CN202220453588 U CN 202220453588U CN 216900573 U CN216900573 U CN 216900573U
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Abstract
The application relates to an immunochromatography test paper strip is with card shell, it is including upper cover and the drain pan that can dismantle the connection, the length of upper cover or drain pan is 9.0 ~ 9.5cm, the width is 1.2 ~ 1.4cm, highly is 0.2 ~ 0.4 cm. The utility model provides an immunochromatography test paper strip is with card shell can use in the integrative detector of single channel, multichannel that receives the space restriction, and not only easy operation can detect a plurality of samples more moreover, and is efficient, and because of the card shell stores shared space less, so also conveniently carry when going out.
Description
Technical Field
The application relates to the technical field of immunoassay, in particular to a card shell for an immunochromatography test strip.
Background
An immunochromatography method (ICA) was established by Oskiowicz et al in 1990. The marker used by Oskiowicz is selenium, and then simple colloidal gold is generally adopted, which is called as a colloidal gold immunochromatographic method. With the development of immunochromatography (immunochromatography) and Gold technology, particularly after the 90 s, Gold immunochromatography assay (GICA) has been widely used for in vitro diagnosis and disease detection.
With the development of rapid detection technology, the fluorescence immunochromatographic technique is also rapidly developed, and is a novel membrane detection technology based on antigen-antibody specific immunoreaction. The technology needs to adopt a special test strip to complete the technology, namely, a strip-shaped fiber chromatography material fixed with a detection line (coated antibody or coated antigen) and a quality control line (antibody) is taken as a stationary phase, a test solution is taken as a mobile phase, a fluorescence labeled antibody or antigen is fixed on a connecting pad, and an analyte moves on the chromatography strip through capillary action. For macromolecular antigens (proteins, viruses, pathogenic bacteria and the like) with a plurality of antigenic determinants, a sandwich type double-antibody sandwich immunochromatography method is generally adopted, namely, an object to be detected is firstly combined with a fluorescence labeling antibody under the action of a mobile phase, and then is combined with a coating antibody to form a sandwich type double-antibody sandwich when reaching a detection line.
At present, in the process of rapid detection, a test strip is generally fixed on a card shell, and then the card shell is directly inserted into an immunofluorescence detector for detection. The test strip is fixed on the card shell, so that after the card shell is inserted into the detector, the detection position of the detector for detecting the test strip is unchanged, and meanwhile, the card shell can protect the test strip. The existing detectors are generally single-channel detectors and multi-channel detectors, wherein the single-channel detectors are divided into single-channel detectors and multi-channel detectors, and the two detectors are different in that the single-channel detectors can only detect one detection card after being installed in a card, and the multi-channel detectors can simultaneously load a plurality of different item detection cards through machining, so that the purpose of detecting a plurality of items at one time is achieved. But in single channel, the integrative detector detection of multichannel, the space restriction that receives during the detection is great, and relevant card shell size is generally great for the quantity that the detector once only detected the sample is limited, complex operation not only, and inefficiency, and it is inconvenient to carry.
SUMMERY OF THE UTILITY MODEL
In order to be suitable for current single channel, the integrative detector of multichannel, this application provides the integrative detector of immunochromatography test paper strip with card shell, the immunochromatography test paper strip with card shell of this application can use in the integrative detector of single channel, multichannel that receives the space restriction, easy operation not only, can detect a plurality of samples moreover more, efficient, and because of the card shell stores shared space less, so also conveniently carry when going out.
The application provides a card shell for immunochromatography test strip adopts the following technical scheme:
the card shell for the immunochromatographic test strip comprises an upper cover and a bottom shell which are detachably connected, wherein the length of the upper cover or the bottom shell is 9.0-9.5 cm, the width of the upper cover or the bottom shell is 1.2-1.4 cm, and the height of the upper cover or the bottom shell is 0.2-0.4 cm.
Through adopting above-mentioned technical scheme, compare in other card shells, card shell in this application has a less size under the unchangeable condition of keeping test paper strip size for the immunochromatography test paper strip of this application can use in the integrative detector of single channel, multichannel that receives the space restriction, and not only easy operation can detect a plurality of samples more moreover, and is efficient, and because of the card shell stores shared space less, so also conveniently carry when going out.
Preferably, the upper cover or the bottom case has a length of 9.0cm, a width of 1.2cm and a height of 0.2 cm.
Through adopting above-mentioned technical scheme, adopt the card shell of above-mentioned size, can make single channel, the integrative detector of multichannel can detect a plurality of samples more, promote detection effect rate.
Preferably, the four corners of the upper cover or the bottom shell are provided with arc chamfers.
The upper cover of card shell and the four corners of drain pan all are smooth convex rectangle structure in this application, can avoid when the card shell is installed and is used, lacerate gloves, cause the injury to operating personnel and lead to the fact the possibility of polluting the product.
Preferably, the internal surface of drain pan is provided with the draw-in groove that is used for placing the test paper strip, the draw-in groove includes two first spacing portions that are used for restricting test paper strip longitudinal movement, first spacing portion sets up for the U type, the opening of first spacing portion sets up relatively, is provided with a plurality of groups between two first spacing portions and is used for restricting test paper strip lateral shifting's the spacing portion of second, and the spacing portion of second of the same group is two rectangular plates that parallel arrangement each other.
Through adopting above-mentioned technical scheme, the size and the mutual adaptation of test paper strip of draw-in groove for the test paper strip can be by stable restriction in the drain pan, reduces the test paper strip and produces the possibility of shifting, thereby promotes and detects the accuracy.
Preferably, the outer surface of the upper cover is provided with a product label mark, a sample adding hole, a result observation window and a direction indication mark in sequence, and one side of the result observation window is provided with a bar code.
By adopting the technical scheme, the product label mark is convenient for users to distinguish different card shells; the direction indicating mark can prompt an operator to carry out correct installation, is convenient for a user to use and is simple and convenient to operate. In the in-service use process, the card shell that will be equipped with the test paper strip is placed horizontally, the application hole faces up, with sample solution dropwise add in the application hole, after 8min static, insert the card shell in the detector according to the direction that direction indication mark shows, the project of automatic scanning discernment product name bar code carries out the reading, immunofluorescence detector gives the measuring result, bar code on the card shell can be automatic by the scanning of detection appearance discernment product name, and the instrument can read the threshold value of this product fast, the trouble of changing the project name has been saved, especially when detecting different products to the multichannel detector, can effectively save check-out time, realize short-term test.
Preferably, the inner surface of the upper cover is provided with a plurality of extrusion points for abutting against the upper surface of the test strip, and the surface of the extrusion points facing the test strip is an arc transition surface.
Through adopting above-mentioned technical scheme, the setting of extrusion point can be on the basis of the good test paper strip of drain pan fixation, and extrusion point butt is at the upper surface of test paper strip to under the cooperation of upper cover and drain pan, make the test paper strip can be stable fix in the card shell, can play fine guard action to the test paper strip.
Preferably, the upper cover is provided with a retention projection extending towards the direction of the test strip on the inner surface of the sample adding hole, and the retention projection abuts against the upper surface of the test strip.
Through adopting above-mentioned technical scheme, holding back the arch and can coordinating the fixed test paper strip of draw-in groove, holding back the arch simultaneously and can holding back getting into the downthehole sample solution of application of sample, through control sample volume, the velocity of flow of control sample on the test paper strip for the testing process is accurate, practical simple and convenient.
Preferably, the inner surface of the upper cover on the result observation window extends towards the direction of the test strip to form a mortgage protrusion, and the mortgage protrusion abuts against the upper surface of the test strip.
Through adopting above-mentioned technical scheme, the mortgage arch can cooperate the fixed test paper strip of draw-in groove, and the protruding velocity of flow and the sample size that can effectual control sample of mortgage simultaneously for the testing process is accurate, practical simple and convenient.
Preferably, the distance between the middle part of the sampling hole and the middle part of the observation window is 2.5-3.0 cm.
By adopting the technical scheme, the sample adding holes and the observation windows with the intervals can give enough flow time to the sample solution, so that the accuracy of the detection result is improved.
Preferably, the inner surface of the upper cover is provided with a plurality of fixing columns, and the inner surface of the bottom shell is provided with fixing holes corresponding to the fixing columns one to one.
Through adopting above-mentioned technical scheme, the interference fit of fixed column and fixed orifices to make upper cover and drain pan realize the buckle and be connected, fixed mode is simple and stable.
Preferably, the inner surfaces of the upper cover and the bottom shell are provided with assembly marks.
By adopting the technical scheme, the arrangement of the assembly marks can avoid the problem that the detection result is inaccurate due to different installation directions of each test strip caused by inconsistent operation of operators.
To sum up, the application comprises the following beneficial technical effects:
1. compared with other card shells, the card shell has smaller size under the condition of keeping the size of the test strip unchanged, so that the card shell for the immunochromatography test strip can be applied to a single-channel and multi-channel integrated detector limited by space, is simple to operate, can detect a plurality of samples, is high in efficiency, and is convenient to carry when going out due to the fact that the card shell occupies a small space for storage;
2. the product label mark is convenient for users to distinguish different card shells; the direction indicating mark can prompt an operator to carry out correct installation, is convenient for a user to use and is simple and convenient to operate;
3. intercepting arch and mortgage arch can cooperate the fixed test paper strip of draw-in groove, intercept simultaneously protruding and the protruding velocity of flow and the sample volume that can effectual control sample of mortgage for the testing process is accurate, practical simple and convenient.
Drawings
FIG. 1 is a front view of a card housing of the present application.
Fig. 2 is a schematic perspective view of the card case of fig. 1 after product label marks, direction indicators and bar codes are hidden.
Fig. 3 is a schematic diagram of an exploded structure of the upper cover of the card case after the upper cover is exploded to open the bottom case.
Fig. 4 is a schematic diagram of another explosion structure of the card housing, which is used to show the matching relationship between the test strip and the card slot.
Fig. 5 is a schematic structural view for embodying the inner surfaces of the upper cover and the bottom case.
In the figure, 1, an upper cover; 11. fixing a column; 12. marking a product label; 13. a sample application hole; 131. trapping the bulge; 14. a result observation window; 141. a mortgage bump; 15. a direction indicating mark; 16. a bar code; 17. a point of extrusion; 2. a bottom case; 21. a fixing hole; 22. a card slot; 221. a first limiting part; 222. a second limiting part; 3. assembling a mark; 4. and (4) a test strip.
Detailed Description
The present application is described in further detail below with reference to the attached drawings.
Examples
Example 1
The embodiment of the application discloses a card shell for an immunochromatographic test strip. Referring to fig. 1 and 2, the cartridge for immunochromatographic test strip includes an upper cover 1 and a bottom case 2 detachably connected, the upper cover 1 and the bottom case 2 are adapted in shape and size and can be engaged with each other, both the upper cover 1 and the bottom case 2 have inner surfaces and outer surfaces, and a space for accommodating the test strip 4 is formed on the inner surfaces of the upper cover 1 and the bottom case 2 when they are engaged with each other.
Referring to fig. 2 and 3, the length of the upper cover 1 or the bottom case 2 is 9.0cm, the width of the upper cover 1 or the bottom case 2 is 1.2cm, and the height of the upper cover 2 or the bottom case is 0.2cm, and arc chamfers are arranged on the peripheral parts of four end corners of the upper cover 1 and the bottom case 2, so that four corners of the clamping case are of smooth arc-shaped rectangular structures, and the possibility that the clamping case scratches gloves when being installed and used, damages to operators and pollutes products can be avoided. Compare in other card shells, card shell in this application has a smaller size under the unchangeable condition of 4 sizes of keeping test paper strip for immunochromatography test paper strip 4 of this application can use in the integrative detector of single channel, multichannel that receives the space restriction, and not only easy operation can detect a plurality of samples more moreover, promotes detection efficiency, and because of the card shell stores shared space less, so also conveniently carry when going out.
Referring to fig. 4 and 5, fixing posts 11 are integrally formed at four end corners of the inner surface of the upper cover 1, respectively, and the fixing posts 11 are perpendicular to the inner surface of the upper cover 1; and also integrated into one piece has two fixed columns 11 between two fixed columns 11 that are located long limit avris at upper cover 1 internal surface, offers the fixed orifices 21 with fixed column 11 one-to-one at the internal surface of drain pan 2, and fixed column 11 can insert in fixed orifices 21 and with fixed orifices 21 interference fit to make upper cover 1 and drain pan 2 pass through fixed column 11 and fixed orifices 21 lock installation. In this embodiment, the card shell is made of low fluorescence background PVC, which can effectively reduce the interference of background fluorescence to the measurement result.
Referring to fig. 4 and 5, a clamping groove 22 for placing the test strip 4 is formed in the middle of the inner surface of the bottom case 2 in an extrusion molding manner, the clamping groove 22 includes two first limiting portions 221 for limiting the test strip 4 to move longitudinally, the first limiting portions 221 are U-shaped, openings of the first limiting portions 221 are oppositely arranged, and a distance between opposite side walls of the two first limiting portions 221 is equal to the length of the test strip 4; two sets of second limit parts 222 used for limiting the lateral movement of the test strip 4 are arranged between the two first limit parts 221, the second limit parts 222 in the same group are two strip-shaped plates arranged in parallel, and the distance between the two second limit parts 222 in the same group is equal to the width of the test strip 4, so that the test strip 4 can be stably limited in the bottom case 2, the possibility of displacement of the test strip 4 is reduced, and the detection accuracy is improved.
Referring to fig. 1 and 5, the outer surface of the upper cover 1 is provided with a product number mark 12, a sample adding hole 13, a result observation window 14 and a direction indication mark 15 in sequence along the central axis thereof, a bar code 16 is provided on one side of the result observation window 14, and the item name of the card case is covered on the direction indication mark 15. The sample adding hole 13 and the result observation window 14 are positioned right above the clamping groove 22 and are opposite to the test strip 4; the sampling hole 13 is an elliptical hole, the result observation window 14 is a waist-shaped long hole, and the distance from the middle part of the sampling hole 13 to the middle part of the observation window is 3.0cm, so that sufficient flowing time is provided for the sample solution, and the accuracy of the detection result is improved. The read information of the bar code 16 is a product label, so that after the card shell is inserted into the detector, the detector can automatically scan and identify the item of the product name bar code 16 for reading, the immunofluorescence detector gives out a measurement result, the detection time can be effectively saved, and the rapid detection is realized. Meanwhile, the inner surfaces of the upper cover 1 and the bottom shell 2 are provided with assembly marks 3; the assembly mark 3 on the inner surface of the upper cover 1 is positioned between the sample adding hole 13 and the result observation window 14, and the assembly mark 3 on the upper cover 1 and the bottom shell 2 are oppositely arranged; the assembly marks 3 on the upper cover 1 and the bottom shell 2 are in the shape of two protruding half arrows, the indication direction of the assembly marks 3 is the same as the direction indication mark 15, the two half arrows can form a completed arrow, and the distance between the two half arrows is equal to the width of the test strip 4, so that an operator can correctly install the card shell.
When assembling the card shell, the test paper strip 4 is placed in the direction of the assembly mark 3 in the clamping groove 22 according to the water absorption paper end, after the position is fixed, the assembly mark 3 on the upper cover 1 and the assembly mark 3 on the bottom shell 2 are installed in a matching mode in the same direction, and then the upper cover 1 and the bottom shell 2 are fixed firmly through the fixing column 11 and the fixing hole 21 through external pressure. Due to the assembly marks 3 and the direction indicating marks 15, the problem that the detection result is inaccurate due to different installation directions of each test strip 4 caused by inconsistent operation of operators can be avoided.
Referring to fig. 5, an interception protrusion 131 extends from the inner surface of the upper cover 1 located in the sample adding hole 13 to the direction of the test strip 4, the inner circumference of the interception protrusion 131 is matched with the outer circumference of the sample adding hole 13, and the interception protrusion 131 abuts against the upper surface of the test strip 4; the inner surface of the upper cover 1 on the result observation window 14 extends to the direction of the test paper strip 4 to form a mortgage protrusion 141, the inner circumference of the mortgage protrusion 141 is matched with the outer circumference of the result observation window 14, and the mortgage protrusion 141 is abutted against the upper surface of the test paper strip 4. The intercepting bulge 131 and the mortgage bulge 141 can be matched with the clamping groove 22 to fix the test paper strip 4, and meanwhile, the intercepting bulge 131 and the mortgage bulge 141 can effectively control the flow rate and the sample volume of a sample, so that the detection process is accurate, practical and simple.
Referring to fig. 5, the internal surface of upper cover 1 is provided with two extrusion points 17 that are used for the butt at test paper strip 4 upper surface, two extrusion points 17 are arranged along the axis of upper cover 1, and two extrusion points 17 are located one side that result observation window 14 kept away from with appearance hole 13, the surface that extrusion point 17 faced test paper strip 4 is circular arc transition surface, thereby reduce the possibility that extrusion point 17 crushes test paper strip 4, and simultaneously, two extrusion points 17 can be on the basis that test paper strip 4 is fixed to bottom shell 2, extrusion point 17 butt is at the upper surface of test paper strip 4, thereby under the cooperation of upper cover 1 and bottom shell 2, make test paper strip 4 can be stable fix in the card shell, can play fine guard action to test paper strip 4, extrusion point 17 can make the flow rate of sample solution when the chromatography stable powerful simultaneously, make the chromatography accelerate, reaction time shortens.
Example 2
The embodiment of the application discloses a card shell for an immunochromatographic test strip, which is different from the embodiment 1 in that the length of an upper cover 1 or a bottom shell 2 is 9.5cm, the width is 1.4cm, and the height is 0.4 cm; the distance from the middle of the sampling hole 13 to the middle of the observation window was 2.5 cm.
Example 3
The embodiment of the application discloses a card shell for an immunochromatographic test strip, which is different from the embodiment 1 in that the length of an upper cover 1 or a bottom shell 2 is 9.2cm, the width is 1.3cm, and the height is 0.3 cm; the distance from the middle of the sample application hole 13 to the middle of the observation window was 2.7 cm.
The implementation principle of the card shell for the immunochromatographic test strip in the embodiment of the application is as follows: in the in-service use process, the card shell that will be equipped with test paper strip 4 is placed horizontally, the application of sample hole 13 faces up, with sample solution dropwise add in application of sample hole 13, after 8min static, insert the card shell in the detector according to the direction that direction indicator 15 shows, the project of automatic scanning discernment product name bar code 16 carries out the reading, immunofluorescence detector gives the measuring result, bar code 16 on the card shell can be automatic by detector scanning discernment product name, and the instrument can read the threshold value of this product fast, the trouble of changing the project name has been saved, especially multichannel detector is when detecting different products, can effectively save check-out time, realize short-term test.
It will be understood that the above embodiments are merely exemplary embodiments adopted to illustrate the principles of the present invention, and the present invention is not limited thereto. It will be apparent to those skilled in the art that various modifications and improvements can be made without departing from the spirit and substance of the invention, and these modifications and improvements are also considered to be within the scope of the invention.
Claims (10)
1. Immune chromatography test paper strip is with card shell, including upper cover (1) and drain pan (2) that can dismantle the connection, its characterized in that: the upper cover (1) or the bottom shell (2) is 9.0-9.5 cm long, 1.2-1.4 cm wide and 0.2-0.4 cm high.
2. The cartridge for the immunochromatographic test strip according to claim 1, characterized in that: the upper cover (1) or the bottom shell (2) is 9.0cm in length, 1.2cm in width and 0.2cm in height.
3. The cartridge for an immunochromatographic test strip according to claim 1, characterized in that: and arc chamfers are arranged at four corners of the upper cover (1) or the bottom shell (2).
4. The cartridge for an immunochromatographic test strip according to claim 1, characterized in that: the internal surface of drain pan (2) is provided with draw-in groove (22) that are used for placing test paper strip (4), draw-in groove (22) include two first spacing portions (221) that are used for restricting test paper strip (4) longitudinal movement, first spacing portion (221) set up for the U type, the opening of first spacing portion (221) sets up relatively, is provided with a plurality of groups between two first spacing portions (221) and is used for restricting spacing portion (222) of second of test paper strip (4) lateral shifting, and spacing portion (222) of second of the same group are two rectangular plates that parallel arrangement each other.
5. The card shell for the immunochromatographic test strip according to claim 4, characterized in that: the outer surface of the upper cover (1) is sequentially provided with a product mark (12), a sampling hole (13), a result observation window (14) and a direction indicating mark (15), and one side of the result observation window (14) is provided with a bar code (16).
6. The cartridge for the immunochromatographic test strip according to claim 4, characterized in that: the inner surface of the upper cover (1) is provided with a plurality of extrusion points (17) which are used for being abutted against the upper surface of the test strip (4), and the surface of each extrusion point (17) facing the test strip (4) is an arc transition surface.
7. The card shell for the immunochromatographic test strip according to claim 5, characterized in that: the inner surface of the upper cover (1) positioned on the sample adding hole (13) extends towards the direction of the test strip (4) to form an interception bulge (131), and the interception bulge (131) is abutted against the upper surface of the test strip (4).
8. The card shell for the immunochromatographic test strip according to claim 7, characterized in that: the inner surface of the upper cover (1) positioned on the result observation window (14) extends towards the direction of the test strip (4) to form a mortgage bulge (141), and the mortgage bulge (141) is abutted to the upper surface of the test strip (4).
9. The cartridge for an immunochromatographic test strip according to any one of claims 1 to 8, characterized in that: the inner surface of the upper cover (1) is provided with a plurality of fixing columns (11), and the inner surface of the bottom shell (2) is provided with fixing holes (21) which correspond to the fixing columns (11) one by one.
10. The cartridge for the immunochromatographic test strip according to claim 9, characterized in that: the inner surfaces of the upper cover (1) and the bottom shell (2) are provided with assembly marks (3).
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CN202220453588.6U CN216900573U (en) | 2022-03-02 | 2022-03-02 | Card shell for immunochromatography test strip |
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CN202220453588.6U CN216900573U (en) | 2022-03-02 | 2022-03-02 | Card shell for immunochromatography test strip |
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