CN216900218U - Hollow optical fiber fluorescence conduction device - Google Patents
Hollow optical fiber fluorescence conduction device Download PDFInfo
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- CN216900218U CN216900218U CN202122665261.3U CN202122665261U CN216900218U CN 216900218 U CN216900218 U CN 216900218U CN 202122665261 U CN202122665261 U CN 202122665261U CN 216900218 U CN216900218 U CN 216900218U
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Abstract
The utility model discloses a hollow optical fiber fluorescence conduction device which comprises a hollow optical fiber, wherein solid optical fibers are installed at two ends of the hollow optical fiber, a cylindrical cavity with a penetrating end part is formed in the axis of the hollow optical fiber, the cylindrical cavity is used for containing liquid to be detected, and an air cavity is formed in the circumferential side of the hollow optical fiber corresponding to the cylindrical cavity in a surrounding mode. In order to reduce the refraction loss effect of the cylindrical cavity, the air cavity is formed in the circumferential side of the cylindrical cavity, the refractive index of air is smaller than that of the inner wall of the cylindrical cavity, when light passes through the side wall of the air cavity, the optical density medium irradiates the optically sparse medium, the optical fiber can be subjected to total reflection, and the light loss caused by refraction is reduced. Therefore, the optical fiber of the air cavity can reduce light loss under the condition of total reflection of the side wall of the air cavity, and can accurately detect even if the light intensity is low and the content of a detected product is low, so that the detection accuracy is improved.
Description
Technical Field
The utility model belongs to the technical field of fluorescence detection, and particularly relates to a hollow optical fiber fluorescence conduction device.
Background
The direction of propagation of light generally changes as it passes from one medium to another, a phenomenon known as refraction of light. When light is obliquely incident from an optically dense medium (large refractive index) into an optically thinner medium (small refractive index), the angle of refraction is larger than the angle of incidence, and the angle of refraction increases with an increase in the angle of incidence. When the angle of incidence increases to a certain value, the refraction phenomenon no longer occurs, and the angle of incidence is called the critical angle.
An optical fiber is composed of a core, a coating layer and a protective layer, the core is generally a fiber made of glass, and is coated with a glass jacket having a lower refractive index than the core. The emitter emits laser loaded with information to be sent into the core wire from the emitting end at an angle larger than the critical angle, the laser continuously generates total reflection in the optical fiber and is transmitted from one end (the emitting end) of the optical fiber to the other end (the receiving end), and energy loss basically does not exist in the whole transmission process.
The collection of fluorescence signals cannot be separated from biological research, and the use of the currently common instruments such as a fluorescence PCR (polymerase chain reaction), a chemiluminescence instrument, an immunofluorescence analyzer and the like all collect and convert the fluorescence signals into electronic values for data analysis, and the efficiency of fluorescence collection directly influences the sensitivity and accuracy of the instruments
Solid optical fibers are widely applied to signal collection and transmission of instruments, fluorescence is transmitted in the solid optical fibers through total internal reflection, loss caused by absorption and scattering of a fiber core is generated in the transmission process, and parameters such as damage threshold, attenuation, nonlinear effect and group velocity dispersion are influenced by corresponding parameters of silicon materials. Through reasonable design, the hollow optical fiber can realize that more than 99% of light is transmitted in the air instead of glass, thereby greatly reducing the influence of the characteristics of the optical fiber material on the optical property and the performance of the optical fiber. Hollow fibers are therefore advantageous over solid fibers in the biosensing field.
The utility model provides a hollow optical fiber fluorescence conduction device which can reduce the loss in the fluorescence transmission process and improve the fluorescence collection efficiency, thereby improving the detection sensitivity of the whole instrument.
SUMMERY OF THE UTILITY MODEL
The utility model aims to provide a hollow optical fiber fluorescence conduction device which can reduce the loss in the fluorescence transmission process and improve the fluorescence collection efficiency, thereby improving the detection sensitivity of the whole instrument.
In order to solve the technical problems, the utility model is realized by the following technical scheme:
a hollow optical fiber fluorescence conduction device comprises a hollow optical fiber, wherein solid optical fibers are arranged at two ends of the hollow optical fiber;
the axis of the hollow optical fiber is provided with a cylindrical cavity with a penetrating end part, the cylindrical cavity is used for containing liquid to be detected, and light of the solid optical fiber enters one end of the cylindrical cavity and is emitted out;
the hollow optical fiber is a cylinder made of a light-transmitting material, an air cavity is formed in the circumferential side of the hollow optical fiber corresponding to the cylindrical cavity in a surrounding mode, and the air cavity is cylindrical and is coaxial with the cylindrical cavity.
Further, the solid core optical fiber comprises an outer insulating layer and an inner core, and the end of the core extends into the cylindrical cavity.
Further, the corresponding ends of the air chamber are sealed.
Furthermore, a sheath layer is sleeved outside the hollow-core optical fiber.
Further, the butt joint ends of the solid-core optical fibers and the hollow-core optical fibers are provided with sealing gaskets.
The utility model has the following beneficial effects:
in order to reduce the refraction loss effect of the cylindrical cavity, an air cavity is formed in the circumferential side of the cylindrical cavity, the refractive index of air is smaller than that of the inner wall of the cylindrical cavity, when light passes through the side wall of the air cavity, the optical density medium irradiates the optically thinner medium, the optical fiber can be subjected to total reflection, and the light loss caused by refraction is reduced. Therefore, the optical fiber of the air cavity can reduce light loss under the condition of total reflection of the side wall of the air cavity, and can accurately detect even if the light intensity is low and the content of a detected product is low, so that the detection accuracy is improved.
Of course, it is not necessary for any product in which the utility model is practiced to achieve all of the above-described advantages at the same time.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings used in the description of the embodiments will be briefly introduced below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and it is obvious for those skilled in the art that other drawings can be obtained according to the drawings without creative efforts.
FIG. 1: the structure of the utility model.
FIG. 2: the hollow optical fiber ribbon has a cut structure diagram.
In the drawings, the components represented by the respective reference numerals are listed below:
the optical fiber comprises a hollow-core optical fiber 1, a solid-core optical fiber 2, a cylindrical cavity 11, an air cavity 12, an insulating layer 21, a fiber core 22, a sheath layer 3 and a sealing gasket 4.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
In the description of the present invention, it is to be understood that the terms "opening," "upper," "lower," "thickness," "top," "middle," "length," "inner," "peripheral," and the like are used in an orientation or positional relationship that is merely for convenience in describing and simplifying the description, and do not indicate or imply that the referenced component or element must have a particular orientation, be constructed and operated in a particular orientation, and thus should not be considered as limiting the present invention.
As shown in fig. 1-2: a hollow optical fiber fluorescence conduction device comprises a hollow optical fiber 1, wherein solid optical fibers 2 are arranged at two ends of the hollow optical fiber 1; the solid optical fiber is a normal optical fiber and is provided with a fiber core, a covering layer and a protective layer, wherein the protective layer is generally a rubber sleeve, the covering layer is formed by coating materials with the refractive index smaller than that of the fiber core, and the fiber core is made of silicon dioxide and additives and can be understood as glass. The laser is emitted into the core wire at an angle larger than the critical angle, and the laser is continuously subjected to total reflection in the optical fiber, so that the energy loss is reduced.
The axis of the hollow-core optical fiber 1 is provided with a cylindrical cavity 11 with a penetrating end part, the cylindrical cavity 11 is used for containing liquid to be detected, and light of the solid-core optical fiber 2 enters one end of the cylindrical cavity 11 and is emitted out; the fluorescence detection device also comprises a light exciter and a light detector, wherein the liquid to be detected is generally experiment liquid capable of being fluorescently marked, a target product is fluorescently marked along with the progress of the experiment, the fluorescence signal intensity is also increased in equal proportion, and a fluorescence intensity signal is collected after each cycle, so that the change of the product amount can be detected through the change of the fluorescence intensity, and a fluorescence amplification curve graph is obtained and used for accurately positioning the change condition of the content of the target product in the liquid.
And the light rays in the excited state of the optical exciter are conducted through the solid optical fiber and enter the cylindrical cavity, and the light in the excited state excites fluorescent molecules and is detected by the optical detector at the tail end. The solid core fiber is provided with a serial optical exciter and a light detector respectively.
The hollow optical fiber 1 is a cylinder made of a light-transmitting material, an air cavity 12 is formed in the circumferential side, corresponding to the cylindrical cavity 11, of the hollow optical fiber 1 in a surrounding mode, and the air cavity 12 is cylindrical and is arranged coaxially with the cylindrical cavity 11. The air cavity is preferably in a vacuum state, and the refractive index of light in the vacuum state is lowest, so that refracted light can be reduced to the maximum extent.
The full-reflection purpose of the optical fiber can be achieved due to the matching of the fiber core and the covering layer of the solid-core optical fiber, but when the optical fiber is transmitted to the cylindrical cavity, a large amount of light can be refracted on the side wall of the cylindrical cavity, so that the light loss is serious, when the light intensity is not enough or the fluorescence labeling quantity of a detected object is less, a detector is difficult to detect a detected target product, and the detection data is inaccurate. Therefore, the hollow-core optical fiber is designed to be an integral cylinder, is integrally formed, is transparent and basically the same as the core material of the optical fiber, and is made of silicon dioxide and additives, such as glass. In order to reduce the refraction loss effect of the cylindrical cavity, an air cavity is formed in the circumferential side of the cylindrical cavity, the refractive index of air is smaller than that of the inner wall of the cylindrical cavity, when light passes through the side wall of the air cavity, the optical density medium irradiates the optically thinner medium, the optical fiber can be subjected to total reflection, and the light loss caused by refraction is reduced. Simultaneously, the air cavity is cylindric, and the lateral wall has the radian, and optic fibre is favorable to making optic fibre and air cavity lateral wall form great incident angle when shining, satisfies the critical angle of optic fibre total reflection condition.
Therefore, the optical fiber of the air cavity can reduce light loss under the condition of total reflection of the side wall of the air cavity, and can accurately detect even if the light intensity is low and the content of a detected product is low, so that the detection accuracy is improved.
As shown in fig. 1: the solid core optical fiber 2 comprises an outer insulating layer 21 and an inner core 22, and the end of the core 22 extends into the cylindrical cavity 11. The fiber core is mainly a substance for transmitting the optical fiber and is in plug-in fit with the cylindrical cavity to prevent light leakage.
As shown in fig. 2: the corresponding ends of the air chamber 12 are sealed. Preventing access to the liquid to be tested.
As shown in fig. 2: and a sheath layer 3 is sleeved outside the hollow optical fiber 1. And (4) protecting a user.
As shown in fig. 1: the butt joint end of the solid optical fiber 2 and the hollow optical fiber 1 is provided with a sealing gasket 4. The device needs to disassemble the hollow optical fiber to inject the detected solution, so the hollow optical fiber and the solid optical fiber are detachably combined, and the sealing gasket is used for improving the sealing property.
In the description herein, references to the description of "one embodiment," "an example," "a specific example," etc., mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the utility model. In this specification, the schematic representations of the terms used above do not necessarily refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.
The preferred embodiments of the utility model disclosed above are intended to be illustrative only. The preferred embodiments are not intended to be exhaustive or to limit the utility model to the precise embodiments disclosed. Obviously, many modifications and variations are possible in light of the above teaching. The embodiments were chosen and described in order to best explain the principles of the utility model and the practical application, to thereby enable others skilled in the art to best understand the utility model for and utilize the utility model. The utility model is limited only by the claims and their full scope and equivalents.
Claims (5)
1. A hollow fiber fluorescence conduction device is characterized in that:
the optical fiber comprises a hollow optical fiber (1), wherein solid optical fibers (2) are arranged at two ends of the hollow optical fiber (1);
the axis of the hollow optical fiber (1) is provided with a cylindrical cavity (11) with a penetrating end part, the cylindrical cavity (11) is used for containing liquid to be detected, and light of the solid optical fiber (2) enters one end of the cylindrical cavity (11) and is emitted out;
the hollow optical fiber (1) is a cylinder made of a light-transmitting material, an air cavity (12) is formed in the hollow optical fiber (1) in a surrounding mode corresponding to the circumferential side of the cylindrical cavity (11), and the air cavity (12) is cylindrical and is coaxial with the cylindrical cavity (11).
2. The hollow-core optical fiber fluorescence conducting device according to claim 1, wherein: the solid core optical fiber (2) comprises an outer insulating layer (21) and an inner fiber core (22), and the end of the fiber core (22) extends into the cylindrical cavity (11).
3. The hollow-core optical fiber fluorescence conducting device according to claim 1, wherein: the corresponding ends of the air chamber (12) are sealed.
4. The hollow-core optical fiber fluorescence conducting device according to claim 1, wherein: and a sheath layer (3) is sleeved outside the hollow optical fiber (1).
5. The hollow-core optical fiber fluorescence conducting device according to claim 1, wherein: and the butt joint end of the solid optical fiber (2) and the hollow optical fiber (1) is provided with a sealing gasket (4).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202122665261.3U CN216900218U (en) | 2021-11-01 | 2021-11-01 | Hollow optical fiber fluorescence conduction device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202122665261.3U CN216900218U (en) | 2021-11-01 | 2021-11-01 | Hollow optical fiber fluorescence conduction device |
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| Publication Number | Publication Date |
|---|---|
| CN216900218U true CN216900218U (en) | 2022-07-05 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN202122665261.3U Active CN216900218U (en) | 2021-11-01 | 2021-11-01 | Hollow optical fiber fluorescence conduction device |
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| CN (1) | CN216900218U (en) |
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2021
- 2021-11-01 CN CN202122665261.3U patent/CN216900218U/en active Active
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