CN216879424U

CN216879424U - PCR (polymerase chain reaction) rapid detection chip applied to water bath type heater

Info

Publication number: CN216879424U
Application number: CN202123340690.XU
Authority: CN
Inventors: 王明杰; 赵钢; 高青松; 王领兵
Original assignee: Henan Yingwen Information Technology Co ltd
Current assignee: Henan Yingwen Information Technology Co ltd
Priority date: 2021-12-28
Filing date: 2021-12-28
Publication date: 2022-07-05
Anticipated expiration: 2031-12-28

Abstract

The embodiment of the utility model discloses a PCR (polymerase chain reaction) rapid detection chip applied to a water bath type heater. The utility model relates to a PCR rapid detection chip applied to a water bath type heater, which comprises: a chip body; the inside of chip main part is equipped with the reaction chamber, the bottom of chip main part is equipped with fixed knot and constructs, the top of chip main part is equipped with seal structure, the top inboard of chip main part still is equipped with the injection conical surface of back taper. The PCR rapid detection chip applied to the water bath type heater adopts a new design idea, so that the detection chip is easier to take and place, and meanwhile, the protection effect of preventing sundries at the opening is better.

Description

PCR (polymerase chain reaction) rapid detection chip applied to water bath type heater

Technical Field

The embodiment of the utility model relates to the technical field of biological detection, in particular to a PCR (polymerase chain reaction) rapid detection chip applied to a water bath type heater.

Background

The water bath PCR amplification instrument is one kind of biological experiment equipment with mature technology and high performance price. The water bath type PCR amplification instrument adopts water as a heat transfer medium and a heat preservation medium to preserve heat and control temperature of PCR reactants, so that the reaction process is relatively stable, and the water bath type PCR amplification instrument is very suitable for being used as common test equipment due to lower cost and high fault tolerance rate.

In order to cooperate with a PCR amplification instrument to carry out reaction, a corresponding detection chip for PCR reaction is also needed. However, due to the characteristics of the water bath type PCR amplification instrument, the detection chip for the current water bath type PCR amplification instrument is not easy to take due to unreasonable structure in the using process, and the consistency of the experimental result is easily influenced due to the external influence in the reaction process.

Disclosure of Invention

The embodiment of the utility model provides a PCR (polymerase chain reaction) rapid detection chip applied to a water bath type heater, aiming at the problems, a new design idea is adopted, so that the detection chip is easier to take and place, and meanwhile, the protection effect of preventing sundries at an opening is better.

The PCR rapid detection chip applied to the water bath type heater provided by the embodiment of the utility model comprises: a chip body;

the inside of chip main part is equipped with the reaction chamber, the bottom of chip main part is equipped with fixed knot and constructs, the top of chip main part is equipped with seal structure, the top inboard of chip main part still is equipped with the injection conical surface of back taper.

By adopting the technical scheme, the sealing structure is arranged at the top of the chip main body and the fixing structure is arranged at the bottom of the chip main body, so that the stability of the chip in a water bath can be kept, the chip is prevented from being toppled over, meanwhile, the entering of sundries is also avoided, in addition, the chip is convenient for an operator to take and place, namely, the chip is turned on one side, and the overflow of the internal structure can be avoided.

Optionally, the fixing structure is a soft patch in a shape of a horn mouth integrally designed with the chip main body.

Adopt this technical scheme, through adopting this technical scheme, can keep vertical state to the chip main part effectively, avoid empting, make things convenient for operating personnel to take out this short-term test chip from the water bath.

Optionally, the bottom of the chip body is further provided with a hard supporting block.

By adopting the technical scheme, the chip main body can keep the shape of the chip main body when being fixed at the bottom of the water bath, and the bottom deformation is avoided, so that the vacuum leakage is realized.

Optionally, the hard support block and the chip body are integrally disposed.

By adopting the technical scheme, the whole strength is better and the device is not easy to damage.

Optionally, the chip body is spindle-shaped.

By adopting the technical scheme, the capacity of reactants in the chip can be effectively improved.

Optionally, the sealing structure is: a soft patch with a radial gap in the center.

Adopt this technical scheme, can use on the one hand to annotate the liquid rifle and push reaction reagent wherein, on the other hand can the reconversion after annotating the liquid rifle and pull out, avoids the foreign matter to get into.

Drawings

In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings needed to be used in the description of the embodiments or the prior art will be briefly introduced below, and it is obvious that the drawings in the following description are some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to these drawings without creative efforts.

FIG. 1 is a perspective view of a PCR rapid detection chip applied to a water bath heater according to an embodiment of the present invention;

FIG. 2 is a cross-sectional view of a PCR rapid test chip applied to a water bath heater according to an embodiment of the present invention;

FIG. 3 is a top view of a PCR rapid detection chip applied to a water bath heater according to an embodiment of the present invention.

The reference numbers in the figures:

1. a chip body; 101. a reaction chamber; 102. a fixed structure; 103. soft paster; 104. injecting a conical surface; 105. hard supporting blocks.

Detailed Description

In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are some, but not all, embodiments of the present invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

In the description of the present invention, it is to be understood that the terms "central," "longitudinal," "lateral," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," "axial," "radial," "circumferential," and the like are used in the indicated orientations and positional relationships based on the drawings for convenience in describing and simplifying the description, but do not indicate or imply that the referenced device or element must have a particular orientation, be constructed and operated in a particular orientation, and thus should not be construed as limiting the utility model.

In the present invention, unless otherwise specifically stated or limited, the terms "mounted," "connected," "fixed," and the like are to be construed broadly and may, for example, be fixedly connected, detachably connected, or integrally formed; the connection can be mechanical connection, electrical connection or communication connection; either directly or indirectly through intervening media, either internally or in any other suitable relationship, unless expressly stated otherwise. The specific meanings of the above terms in the present invention can be understood by those skilled in the art according to specific situations. The technical solution of the present invention will be described in detail below with specific examples. The following several specific embodiments may be combined with each other, and details of the same or similar concepts or processes may not be repeated in some embodiments.

Fig. 1 is a perspective view of a PCR rapid detection chip applied to a water bath heater according to an embodiment of the present invention, fig. 2 is a cross-sectional view of the PCR rapid detection chip applied to the water bath heater according to the embodiment of the present invention, and fig. 3 is a top view of the PCR rapid detection chip applied to the water bath heater according to the embodiment of the present invention.

As shown in fig. 1 to 3, the PCR chip for rapid detection applied to a water bath heater according to an embodiment of the present invention includes: a chip body 1.

The PCR rapid detection chip is a container for performing PCR reaction, a reaction chamber 101 is provided in the chip main body 1, and various materials to be reacted are placed in the reaction chamber 101. One possible structure of the chip body 1 is shown in fig. 2. A fixing structure 102 is further provided at the bottom of the chip body 1, and the form of the fixing structure 102 may be various, and functions to keep the chip body 1 fixed in water and in a vertical state in the water bath type heater. The top of the chip main body 1 is provided with a sealing structure, and the sealing structure is used for keeping the mouth part in a sealing state and avoiding sundries from entering. Meanwhile, as shown in fig. 2, an inverted conical injection taper surface 104 is further provided on the inner side of the top of the chip body 1, and the injection taper surface 104 is provided to allow the reaction reagent to flow into the reaction chamber 101 as much as possible, thereby preventing the reaction reagent from adhering to the inner wall.

By adopting the technical scheme, the sealing structure is arranged at the top of the chip main body 1, the fixing structure 102 is arranged at the bottom of the chip main body, the stability of the chip in a water bath can be kept, the chip is prevented from being toppled over, meanwhile, the entering of sundries is also avoided, in addition, the chip is convenient for an operator to take and place, namely, the chip is turned on one side, and the overflow of the internal structure can also be avoided.

Alternatively, as shown in fig. 2, the fixing structure is a soft patch 103 in a bell mouth shape integrally designed with the chip body 1. Specifically, the horn mouth design is adopted, so that when the chip is placed in a water bath, air between the chip main body 1 and the bottom of the water bath is squeezed out by force of hands, the chip main body 1 is fixed, and the chip is prevented from falling in the water bath.

Adopt this technical scheme, through adopting this technical scheme, can keep vertical state to chip main part 1 effectively, avoid empting, make things convenient for operating personnel to take out this short-term test chip from the water bath.

Optionally, a hard supporting block 105 is further disposed at the bottom of the chip body 1. As shown in fig. 2, a hard support block is disposed at this position, so as to effectively prevent the bottom of the chip from deforming, and the chip can maintain its shape.

By adopting the technical scheme, the chip main body 1 can keep the shape of the chip main body when being fixed at the bottom of the water bath, and the bottom deformation is avoided, so that the vacuum leakage is realized.

Optionally, the hard support block 105 and the chip body 1 are integrally provided. For example, by injection molding in one step.

Alternatively, as shown in fig. 2, the chip body 1 has a spindle shape.

Optionally, as shown in fig. 3, the sealing structure is: a soft patch 103 with a radial slit in the center.

In the present invention, unless otherwise explicitly specified or limited, the first feature "on" or "under" the second feature may be directly contacting the first feature and the second feature or indirectly contacting the first feature and the second feature through an intermediate.

Also, a first feature "on," "above," and "over" a second feature may be directly on or obliquely above the second feature, or may simply mean that the first feature is at a higher level than the second feature. A first feature being "under," "below," and "beneath" a second feature may be directly under or obliquely under the first feature, or may simply mean that the first feature is at a lower level than the second feature.

In the description of the specification, reference to the description of "one embodiment," "some embodiments," "an example," "a specific example" or "some examples" or the like is intended to mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the utility model. In this specification, the schematic representations of the terms used above are not necessarily intended to refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples. Furthermore, various embodiments or examples and features of different embodiments or examples described in this specification can be combined and combined by one skilled in the art without contradiction.

Finally, it should be noted that: the above embodiments are only used to illustrate the technical solution of the present invention, and not to limit the same; while the utility model has been described in detail and with reference to the foregoing embodiments, it will be understood by those skilled in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some or all of the technical features may be equivalently replaced; and these modifications or substitutions do not depart from the spirit of the corresponding technical solutions of the embodiments of the present invention.

Claims

1. The utility model provides a be applied to PCR short-term test chip of water bath formula heater which characterized in that includes: a chip body;

2. The chip for PCR rapid detection according to claim 1, wherein the fixing structure is a soft flared patch integrally designed with the chip body.

3. The chip for PCR rapid detection according to claim 2, wherein a hard support block is further disposed at the bottom of the chip body.

4. The chip for PCR rapid detection according to claim 3, wherein the rigid support block and the chip body are integrally disposed.

5. The PCR rapid detection chip according to any one of claims 1 to 4, wherein the chip body is spindle-shaped.

6. The chip for rapid detection of PCR according to claim 5, wherein the sealing structure is: a soft patch with a radial gap in the center.