CN216847145U - Immunohistochemical dyeing machine - Google Patents
Immunohistochemical dyeing machine Download PDFInfo
- Publication number
- CN216847145U CN216847145U CN202123106202.9U CN202123106202U CN216847145U CN 216847145 U CN216847145 U CN 216847145U CN 202123106202 U CN202123106202 U CN 202123106202U CN 216847145 U CN216847145 U CN 216847145U
- Authority
- CN
- China
- Prior art keywords
- needle
- liquid
- slide
- driving assembly
- assembly
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Images
Landscapes
- Sampling And Sample Adjustment (AREA)
Abstract
The utility model discloses an immunohistochemical dyeing machine, including the board and locate stock solution device, dyeing apparatus and the liquid-transfering device on the board respectively, the stock solution device is used for storing the reagent, the dyeing apparatus is used for bearing the slide glass of treating processing, the liquid-transfering device is used for adding the reagent in the stock solution device to the slide glass, the dyeing apparatus includes a plurality of water trough subassemblies that can independently open and close, the slide glass is fixed in the water trough subassembly, the liquid-transfering device includes notes liquid needle and drawing liquid needle, notes liquid needle is used for dripping reagent to the slide glass, drawing liquid needle is used for suspending above the slide glass and extracting the waste liquid on the slide glass; the water tank assemblies capable of being independently opened and closed are arranged to load the glass slide, reagents are dripped into the glass slide through the liquid injection needles, waste liquid on the glass slide is extracted through the liquid extraction needles suspended above the glass slide, cleanliness of the surface environment of the glass slide can be guaranteed, and meanwhile certain liquid is reserved on the surface of the glass slide to prevent drying.
Description
Technical Field
The utility model relates to the technical field of medical equipment, especially, relate to an immunohistochemical dyeing machine.
Background
The immunohistochemical staining machine can replace a pathologist doctor to automatically perform a complicated manual staining process on tissue slices attached to a glass slide, and is an instrument for automatically completing immunohistochemical staining operation.
The technical condition that the immunohistochemical staining machine must guarantee in the using process is that the slide glass does not dry in the staining process, otherwise, nonspecific staining can be caused;
for example, chinese patent application No. CN105571925A discloses a staining module and a staining method for a biological sample on a slide, and specifically discloses a solution for removing waste liquid on the slide by blowing, which can quickly remove the waste liquid, but easily causes liquid splash during blowing, and easily washes off all the waste liquid on the slide by too large wind force to cause drying; some schemes also adopt a small plastic cover added on the surface of the slide to provide a closed incubation environment for immune reaction and prevent the reagent from volatilizing, but the scheme has extremely high requirement on temperature control precision, and if the temperature control is not in place, the risk of drying the slide still exists.
SUMMERY OF THE UTILITY MODEL
The utility model discloses the technical problem that will solve is: an immunohistochemical staining machine is provided to reduce the risk of slide drying.
In order to solve the technical problem, the utility model discloses a technical scheme be: the utility model provides an immunohistochemical dyeing machine, includes the board and locates stock solution device, dyeing apparatus and the liquid-transfering device on the board respectively, the stock solution device is used for storing the reagent, the dyeing apparatus is used for bearing the slide glass of treating processing, the liquid-transfering device is used for adding the reagent in the stock solution device to on the slide glass, the dyeing apparatus includes a plurality of water tank subassemblies that can independently open and close, the slide glass is fixed in the water tank subassembly, the liquid-transfering device includes notes liquid needle and drawing needle, notes liquid needle is used for to the slide glass dropwise add reagent, drawing needle is used for hanging in slide glass top and extract the waste liquid on the slide glass.
Further, the liquid transfer device further comprises a first driving assembly, a second driving assembly, a third driving assembly and a suspended needle assembly, wherein the first driving assembly is mounted on the machine table, the second driving assembly is mounted on the first driving assembly, and the first driving assembly drives the second driving assembly to move along the X-axis direction; the third driving assembly is arranged on the second driving assembly, and the third driving assembly is driven to move along the Y-axis direction by the second driving assembly; the suspended needle assembly is mounted on the third driving assembly, the suspended needle assembly is driven to move along the Z-axis direction by the third driving assembly, and the liquid injection needle and the liquid extraction needle are respectively arranged at the bottom of the suspended needle assembly.
Further, unsettled needle subassembly includes first installation needle bar and second installation needle bar, annotate the liquid needle and include first syringe needle and second syringe needle, first syringe needle is used for dripping the reagent that increases the dosage, the second syringe needle is used for dropwise add trace reagent, first syringe needle with the drawing liquid needle install respectively in first installation needle bar bottom, the second syringe needle install in second installation needle bar bottom.
Further, the length of the first needle head is smaller than that of the liquid drawing needle.
Furthermore, a liquid level sensor is further arranged on the second needle head and used for detecting the liquid level height in the water tank assembly.
Further, the water trough component comprises a box body, a cover body and a slide rack, wherein the cover body is rotatably arranged on the box body, and the slide rack is detachably arranged in the box body and used for placing the slide.
Furthermore, a handle is arranged on the slide rack.
Furthermore, a condensation guide plate for guiding condensed water is arranged on the inner side of the cover body.
Furthermore, the inner peripheral side of the cover body is also provided with a sealing ring matched with the opening above the box body.
The beneficial effects of the utility model reside in that: the utility model provides an immunohistochemical dyeing machine can reduce the risk that the slide dried the piece, sets up a plurality of water tank subassemblies that can independently open and close and loads the slide, through annotating liquid needle to slide dropwise add reagent to through the waste liquid on the liquid extraction needle extraction slide of suspension in slide top, can guarantee that the slide surface environment's cleanliness has ensured simultaneously that the slide surface leaves certain liquid and prevents the piece futilely.
Drawings
Fig. 1 is an assembly view of an immunohistochemical staining machine according to an embodiment of the present invention;
fig. 2 is a schematic structural diagram of a liquid transfer device of an immunohistochemical staining machine according to an embodiment of the present invention;
FIG. 3 is a detail view at A of FIG. 2;
fig. 4 is a schematic structural view of the bottom of the first mounting needle bar of the immunohistochemical staining machine according to an embodiment of the present invention;
fig. 5 is a schematic structural diagram of a water tank assembly of an immunohistochemical staining machine according to an embodiment of the present invention.
Description of reference numerals:
1. a machine platform; 11. a liquid path interface; 12. a display screen; 13. a cover is turned; 14. a bulk reagent reservoir; 15. a needle washing device; 16. a micro reagent storage device; 2. a pipetting device; 21. a first drive assembly; 211. a first drive motor; 212. a first drive belt structure; 22. a second drive assembly; 221. a second drive motor; 222. a second drive belt structure; 23. a third drive assembly; 231. a transmission rod structure; 232. a mounting seat; 233. a drive rack; 24. a suspended needle assembly; 241. a first mounting needle bar; 242. a second mounting needle bar; 25. a liquid drawing needle; 26. a first needle; 27. a second needle; 3. a sink assembly; 31. a box body; 32. a cover body; 321. a condensation guide plate; 322. a seal ring; 33. a slide rack; 331. a handle; 332. a glass slide; 34. a third drive motor; 35. a third drive belt structure; 36. and a limit sensor.
Detailed Description
In order to explain the technical content, the objects and the effects of the present invention in detail, the following description is made with reference to the accompanying drawings in combination with the embodiments.
Referring to fig. 1 to 5, an immunohistochemical staining machine includes a machine table 1, and a liquid storage device, a staining device, and a liquid transfer device 2 respectively disposed on the machine table 1, wherein the liquid storage device is configured to store a reagent, the staining device is configured to carry a slide 332 to be processed, the liquid transfer device 2 is configured to add the reagent in the liquid storage device to the slide 332, the staining device includes a plurality of independently openable and closable water tank assemblies 3, the slide 332 is fixed in the water tank assemblies 3, the liquid transfer device 2 includes a liquid injection needle and a liquid extraction needle 25, the liquid injection needle is configured to drop the reagent to the slide 332, and the liquid extraction needle 25 is configured to suspend above the slide 332 and extract a waste liquid on the slide 332.
From the above description, the beneficial effects of the present invention are: the water tank assemblies 3 which can be independently opened and closed are arranged to load the glass slide 332, reagents are dripped into the glass slide 332 through the liquid injection needles, waste liquid on the glass slide 332 is extracted through the liquid extraction needles 25 suspended above the glass slide 332, cleanliness of the surface environment of the glass slide 332 can be guaranteed, and meanwhile certain liquid left on the surface of the glass slide 332 is guaranteed to be used for placing dry sheets.
Further, the pipetting device 2 further comprises a first driving assembly 21, a second driving assembly 22, a third driving assembly 23 and a suspended needle assembly 24, wherein the first driving assembly 21 is mounted on the machine platform 1, the second driving assembly 22 is mounted on the first driving assembly 21, and the first driving assembly 21 drives the second driving assembly 22 to move along the X-axis direction; the third driving assembly 23 is mounted on the second driving assembly 22, and the second driving assembly 22 drives the third driving assembly 23 to move along the Y-axis direction; the hanging needle assembly 24 is mounted on the third driving assembly 23, the hanging needle assembly 24 is driven by the third driving assembly 23 to move along the Z-axis direction, and the infusion needle and the drawing needle 25 are respectively disposed at the bottom of the hanging needle assembly 24.
As can be seen from the above description, the pipetting device 2 can realize multi-axis movement of the pipetting needle and the pipetting needle 25, so as to facilitate reagent dripping and waste liquid extraction on the slides 332 in the plurality of water trough assemblies 3.
Further, the unsettled needle assembly 24 includes a first installation needle bar 241 and a second installation needle bar 242, the liquid injection needle includes a first needle 26 and a second needle 27, the first needle 26 is used for dripping the reagent of increasing dosage, the second needle 27 is used for dripping the trace reagent, the first needle 26 with the drawing needle 25 is installed respectively in the first installation needle bar 241 bottom, the second needle 27 is installed in the second installation needle bar 242 bottom.
As can be seen from the above description, the first needle 26 is used for dripping a large amount of reagent, and the second needle 27 is used for dripping a small amount of reagent, so that the dripping accuracy of the reagent is enhanced, and the waste of the reagent is avoided.
Further, the length of the first needle 26 is smaller than the length of the liquid drawing needle 25.
As is apparent from the above description, providing the first needle 26 with a length smaller than that of the liquid drawing needle 25 ensures that the reagent can smoothly drip out of the first needle 26.
Further, a liquid level sensor is further arranged on the second needle 27 and is used for detecting the liquid level in the water trough assembly 3.
Further, the sink assembly 3 includes a box body 31, a cover 32 and a slide rack 33, wherein the cover 32 is rotatably mounted on the box body 31, and the slide rack 33 is detachably mounted in the box body 31 for placing the slide 332.
As can be seen from the above description, the cover 32 can cover the slide 332 in the box body 31 for incubation, so as to provide a closed incubation environment for the slide 332, and the slide rack 33 is provided to load the slide 332, so that the slide rack 33 can be mounted in the box body 31 after a plurality of slides 332 are fixed on the slide rack 33, thereby improving the working efficiency.
Further, a handle 331 is provided on the slide rack 33.
As can be seen from the above description, the handle 331 facilitates removal of the slide rack 33, enhancing ease of operation.
Further, a condensation guide plate 321 for guiding condensed water is disposed inside the cover 32.
As can be seen from the above description, the condensation guide 321 can guide the condensed water on the cover 32 to the region inside the box body 31 except for the slide 332, so as to prevent the condensed water from dripping on the slide 332 to affect the dyeing result.
Further, a sealing ring 322 engaged with the upper opening of the box 31 is disposed on the inner peripheral side of the cover 32. As can be seen from the above description, the sealing ring 322 ensures the sealing performance of the water tank assembly 3 after closing.
Example one
Referring to fig. 1 to 5, a first embodiment of the present invention is: an immunohistochemical staining machine is used for automatically staining tissue slices attached to a glass slide 332 and comprises a machine table 1, and a liquid storage device, a staining device and a liquid transferring device 2 which are respectively arranged on the machine table 1, wherein the liquid storage device is used for storing reagents, and the staining device is used for bearing the glass slide 332 to be processed; the liquid-transferring device 2 is used for adding the reagent in the liquid-storing device to the slide 332, and the liquid-transferring device 2 is controlled by a control system in the machine table 1; the staining device comprises a plurality of water tank assemblies 3 which can be independently opened and closed, the glass slide 332 is fixed in the water tank assemblies 3, the liquid transferring device 2 comprises a liquid injecting needle and a liquid extracting needle 25, the liquid injecting needle is used for dropping a reagent on the glass slide 332, and the liquid extracting needle 25 is used for suspending above the glass slide 332 and extracting waste liquid on the glass slide 332.
Specifically, the liquid storage device comprises a large-dose reagent liquid storage device 14 for storing a large-dose reagent and a trace reagent liquid storage device 16 for storing a trace reagent, the large-dose reagent comprises antigen repair liquid, pure water, slide blue returning liquid, hematoxylin and the like, a liquid path interface 11 communicated with the large-dose reagent liquid storage device 14 and the trace reagent liquid storage device 16 is arranged on the side wall of the machine table 1, the large-dose reagent liquid storage device 14 and the trace reagent liquid storage device 16 are respectively connected with the liquid injection needle through peristaltic pumps, more specifically, a flip cover 13 for sealing the liquid storage device, the dyeing device and the liquid transfer device 2 is further arranged on the machine table 1, and the flip cover 13 is rotatably connected with the machine table 1; in detail, a touch display screen 12 connected with the control system is further arranged on one side of the machine 1; in more detail, the machine table 1 is provided with a needle washing device 15 for washing the liquid suction needle 25 and the liquid injection needle.
Preferably, referring to fig. 2, the pipetting device 2 further includes a first driving assembly 21, a second driving assembly 22, a third driving assembly 23, and a flying needle assembly 24, wherein the first driving assembly 21 is mounted on the machine platform 1, the second driving assembly 22 is mounted on the first driving assembly 21, and the first driving assembly 21 drives the second driving assembly 22 to move along the X-axis direction; the third driving assembly 23 is mounted on the second driving assembly 22, and the second driving assembly 22 drives the third driving assembly 23 to move along the Y-axis direction; the suspended needle assembly 24 is mounted on the third driving assembly 23, the suspended needle assembly 24 is driven by the third driving assembly 23 to move along the Z-axis direction, and the infusion needle and the drawing needle 25 are respectively arranged at the bottom of the suspended needle assembly 24; specifically, the first driving assembly 21 includes a first driving motor 211 disposed on the machine platform 1 and a first driving belt structure 212 connected to the first driving motor 211, the first driving belt structure 212 extends along the X direction, and the second driving assembly 22 is connected to the first driving belt structure 212; the second driving assembly 22 includes a second driving motor 221 and a second driving belt structure 222 connected to the second driving motor 221, the second driving belt structure 222 extends along the Y-axis direction, the third driving assembly 23 includes a driving belt structure 231, a mounting seat 232 and a driving rack 233, the mounting seat 232 is mounted on the second driving belt structure 222, the mounting seat 232 is driven by the second driving belt structure 222 to move along the Y-axis direction, the driving rack 233 is engaged with the driving belt structure 231, the driving rack 233 is driven by the driving belt structure 231 to move along the Z-axis direction, and the unsettled needle assembly 24 is mounted on the driving rack 233.
In this embodiment, the unsettled needle assembly 24 includes a first mounting needle bar 241 and a second mounting needle bar 242, the number of the transmission racks 233 and the transmission rod structures 231 is two, and the two transmission racks 233 and the transmission rod structures 231 are driven in one-to-one correspondence, the first mounting needle bar 241 is mounted on one of the transmission racks 233, the second mounting needle bar 242 is mounted on the other transmission rack 233, and the two transmission racks 233 are driven individually by the transmission rod structures 231 connected to the two transmission racks 233; the liquid injection needle comprises a first needle head 26 and a second needle head 27, the first needle head 26 is used for dripping a large dosage of reagent, the second needle head 27 is used for dripping a trace amount of reagent, the first needle head 26 and the liquid drawing needle 25 are respectively installed at the bottom of the first installation needle rod 241, the second needle head 27 is installed at the bottom of the second installation needle rod 242, the first needle head 26 is used for dripping a large dosage of reagent, and the second needle head 27 is used for dripping a trace dosage of reagent, so that the reagent dripping accuracy is enhanced, the reagent waste is avoided, and particularly, the length of the first needle head 26 is smaller than that of the liquid drawing needle 25, so that the reagent can be smoothly dripped out from the first needle head 26; more specifically, a liquid level sensor (not shown) is further disposed on the second needle 27 for detecting the liquid level in the water tank assembly 3; when the first needle 26 adds the large dose of reagent into the water tank assembly 3, the second needle descends to a certain height position in the water tank assembly 3, and when the reagent added into the water tank assembly 3 reaches a certain amount, a signal is transmitted to a control system on the machine platform 1 through the liquid level sensor, so that the first needle 26 stops injecting liquid into the water tank assembly 3.
In detail, referring to fig. 4, the number of the first needles 26 and the number of the liquid drawing needles 25 are plural, the first needle 26 is installed at the center of the bottom of the first installation needle bar 241, and the plural liquid drawing needles 25 are uniformly arranged around the first needle 26 at the bottom of the first installation needle bar 241.
Preferably, the sink assembly 3 comprises a box body 31, a cover 32 and a slide rack 33, wherein the cover 32 is rotatably mounted on the box body 31, and the slide rack 33 is detachably mounted in the box body 31 for holding the slide 332; the cover 32 can cover the slide 332 in the cassette body 31 for incubation, so as to provide a closed incubation environment for the slide 332, and the slide rack 33 is provided for loading the slide 332, so that the slide rack 33 can be installed in the cassette body 31 after a plurality of slides 332 are fixed on the slide rack 33, thereby improving the working efficiency; specifically, the handle 331 is arranged on the slide rack 33, and the handle 331 is convenient for the slide rack 33 to take away, so that the convenience of operation is enhanced; the condensation guide plate 321 for guiding the condensed water is arranged on the inner side of the cover body 32, and the condensation guide plate 321 can guide the condensed water on the cover body 32 to the region, except for the glass slide 332, in the box body 31, so as to prevent the condensed water from dropping on the glass slide 332 to affect the dyeing result; more specifically, a sealing ring 322 engaged with the upper opening of the case 31 is further provided on the inner peripheral side of the lid 32. As can be seen from the above description, the sealing ring 322 ensures the sealing property of the sink assembly 3 after closing.
In this embodiment, the cover 32 is provided with a rotating shaft, the cover 32 is hinged to the box body 31 through the rotating shaft, one end of the rotating shaft is exposed out of the cover 32, the box body 31 is further provided with a third driving motor 34 and a third transmission belt structure 35, which are connected with each other, the third driving motor 34 is arranged at the bottom of the box body 31, and the third transmission belt is connected with the rotating shaft to drive the rotating shaft to rotate, so as to open and close the cover 32; specifically, the box body 31 is further provided with a limit sensor 36 for detecting the stroke of the third transmission belt assembly, and the limit sensor 36 is in communication connection with the third driving motor 34, so that the cover 32 can be accurately opened and closed.
The specific dyeing steps in this example are as follows:
1. manually checking whether each reagent in the liquid storage device meets the requirement of checking the use amount of the sample;
2. placing the glass slide 332 into absolute ethyl alcohol, fixing for 10min, and drying at normal temperature;
3. placing the glass slide 332 into the glass slide rack 33, clicking a water tank switch button of the touch display screen 12 to open the cover 32 of the corresponding water tank assembly 3, then placing the glass slide rack 33 into the box body 31, and then closing the cover 32;
4. closing the cover body 32, starting an antigen retrieval program to automatically open the water tank assembly 3 needing to be added with the retrieval liquid, moving the first needle 26 to the position above the box body 31 through the liquid moving device 2 to start adding the antigen retrieval liquid, descending the second needle 27 to a certain height for detecting the liquid level, moving the first needle 26 away from the avoiding position after detecting the liquid level, closing the cover body 32, and starting the antigen retrieval program after closing the water tank assembly 3;
5. after the antigen retrieval is completed, the interior of the box body 31 is cooled, the temperature of the antigen retrieval liquid in the box body 31 is reduced to below 60 ℃, then a reminding sound is sent, the interface of the touch display screen 12 is used for reminding the end of the retrieval experiment, the cover body 32 can be opened by a user, and after the cover body 32 is opened, the glass slide 332 in the box body 31 can be circled by using a grouping pen.
6. After the circle drawing is finished, the antigen repairing liquid waste liquid on the glass slide 332 is pumped out through the liquid pumping needle 25, the cover body 32 and the turnover cover 13 of the machine table 1 are closed, and all subsequent experimental steps can be fully automatically completed by starting the subsequent experimental steps;
7. then the instrument automatically finishes the discharge of the repair waste liquid in the water tank component 3 and the filling of water bath clear water in the water tank component 3;
8. after the temperature in the water bath assembly 3 is cooled to room temperature, the slide 332 is rinsed 3minx3 times with the cleaning solution.
9. The second needle 27 is driven by the pipetting device 2 to directly drip reagents such as: DAB color development liquid or FastRed color development liquid, then the water tank is closed to cover and is incubated and developed;
after the experiment was completed, the slide mount was removed and the experimental results were observed under a microscope.
To sum up, the utility model provides an immunohistochemical dyeing machine can reduce the risk of the dry piece of slide glass, sets up a plurality of water tank subassemblies that can independently open and close and load the slide glass, through annotating liquid needle to slide glass dropwise add reagent to through the waste liquid on the liquid extraction needle extraction slide glass of suspension in slide glass top, can guarantee the cleanliness of slide glass surface environment and guarantee simultaneously that the slide glass surface leaves certain liquid and prevent the dry piece.
The above mentioned is only the embodiment of the present invention, and not the limitation of the patent scope of the present invention, all the equivalent transformations made by the contents of the specification and the drawings, or the direct or indirect application in the related technical field, are included in the patent protection scope of the present invention.
Claims (9)
1. The utility model provides an immunohistochemical dyeing machine, includes the board and locates stock solution device, dyeing apparatus and the liquid-moving device on the board respectively, the stock solution device is used for storing the reagent, the dyeing apparatus is used for bearing the slide glass of treating processing, the liquid-moving device is used for adding the reagent in the stock solution device to on the slide glass, its characterized in that, the dyeing apparatus includes a plurality of water tank subassemblies that can independently open and close, the slide glass is fixed in the water tank subassembly, the liquid-moving device includes notes liquid needle and drawing needle, notes liquid needle is used for to the slide glass dropwise add reagent, the drawing needle is used for hanging in the slide glass top and extract the waste liquid on the slide glass.
2. The immunohistochemical staining machine of claim 1, wherein the pipetting device further comprises a first driving assembly, a second driving assembly, a third driving assembly and a flying needle assembly, wherein the first driving assembly is mounted on the machine table, the second driving assembly is mounted on the first driving assembly, and the first driving assembly drives the second driving assembly to move along the X-axis direction; the third driving assembly is arranged on the second driving assembly, and the third driving assembly is driven to move along the Y-axis direction by the second driving assembly; the suspended needle assembly is mounted on the third driving assembly, the suspended needle assembly is driven to move along the Z-axis direction by the third driving assembly, and the liquid injection needle and the liquid extraction needle are respectively arranged at the bottom of the suspended needle assembly.
3. The immunohistochemical staining machine of claim 2, wherein the hanging needle assembly comprises a first mounting needle bar and a second mounting needle bar, the filling needle comprises a first needle head and a second needle head, the first needle head is used for dripping a large dosage of reagent, the second needle head is used for dripping a trace amount of reagent, the first needle head and the liquid drawing needle are respectively mounted at the bottom of the first mounting needle bar, and the second needle head is mounted at the bottom of the second mounting needle bar.
4. The immunohistochemical staining machine of claim 3, wherein the first needle head has a length less than a length of the drawing needle.
5. The immunohistochemical staining machine of claim 3, wherein said second needle further comprises a level sensor for detecting a level of liquid in said sump assembly.
6. The immunohistochemical staining machine of claim 1 wherein the sump assembly comprises a box body, a cover rotatably mounted to the box body, and a slide rack removably mounted within the box body for holding the slides.
7. The immunohistochemical staining machine of claim 6, wherein said slide holder is provided with a handle.
8. Immunohistochemical staining machine according to claim 6, characterized in that inside the cover is provided a condensation guide for draining condensed water.
9. The immunohistochemical staining machine of claim 6, wherein the inner peripheral side of the cover body is further provided with a sealing ring which is matched with an opening above the box body.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202123106202.9U CN216847145U (en) | 2021-12-07 | 2021-12-07 | Immunohistochemical dyeing machine |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202123106202.9U CN216847145U (en) | 2021-12-07 | 2021-12-07 | Immunohistochemical dyeing machine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN216847145U true CN216847145U (en) | 2022-06-28 |
Family
ID=82107193
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202123106202.9U Active CN216847145U (en) | 2021-12-07 | 2021-12-07 | Immunohistochemical dyeing machine |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN216847145U (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116413111A (en) * | 2023-06-08 | 2023-07-11 | 深圳市森盈生物科技有限公司 | Intelligent dyeing control method and intelligent dyeing double-hole machine |
| CN116481879A (en) * | 2023-04-06 | 2023-07-25 | 浙江莱阅病理诊断科技有限公司 | Immunohistochemical staining method |
| CN116793796A (en) * | 2022-11-07 | 2023-09-22 | 广州泰立生物科技有限公司 | Automatic immunohistochemical dyeing machine and immunohistochemical dyeing process |
-
2021
- 2021-12-07 CN CN202123106202.9U patent/CN216847145U/en active Active
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116793796A (en) * | 2022-11-07 | 2023-09-22 | 广州泰立生物科技有限公司 | Automatic immunohistochemical dyeing machine and immunohistochemical dyeing process |
| CN116793796B (en) * | 2022-11-07 | 2024-01-23 | 广州泰立生物科技有限公司 | Automatic immunohistochemical dyeing machine and immunohistochemical dyeing process |
| CN116481879A (en) * | 2023-04-06 | 2023-07-25 | 浙江莱阅病理诊断科技有限公司 | Immunohistochemical staining method |
| CN116413111A (en) * | 2023-06-08 | 2023-07-11 | 深圳市森盈生物科技有限公司 | Intelligent dyeing control method and intelligent dyeing double-hole machine |
| CN116413111B (en) * | 2023-06-08 | 2023-08-11 | 深圳市森盈生物科技有限公司 | Intelligent dyeing control method and intelligent dyeing double-hole machine |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN216847145U (en) | Immunohistochemical dyeing machine | |
| CN1088840C (en) | Staining apparatus for staining of tissue specimens on microscope slides | |
| CN104272083B (en) | System, equipment and device for pretreatment cell | |
| US7758809B2 (en) | Method and system for pretreatment of tissue slides | |
| CN103399161B (en) | Portable full-automatic chemiluminescence immune assay system and assay method thereof | |
| JP5658226B2 (en) | Automatic slide processing system | |
| WO2016107057A1 (en) | Fully-automatic immunofluorescence quantitative analysis device and detection method | |
| NO301302B1 (en) | Device for cleaning a sampling needle | |
| EP3330366B1 (en) | Method and device for moving object | |
| WO2023109914A1 (en) | Liquid-based slide preparation device and slide preparation method of sample | |
| CN110133244B (en) | Chemiluminescent immunoassay analyzer, liquid suction needle mechanism and cleaning method thereof | |
| CN204064766U (en) | A kind of Full Automatic Liquid basal cell length of schooling sheet coloring system | |
| CN115112912A (en) | Multi-project body fluid analyzer | |
| CN217466952U (en) | Full-automatic thrombelastogram instrument | |
| CN109030151B (en) | Liquid-based tableting method | |
| CN107532979A (en) | Device for analyzing samples and its control method | |
| CN208060258U (en) | A kind of full-automatic glass slide smear dyeing machine | |
| CN115839872B (en) | Full-automatic liquid-based cell slice-making dyeing machine | |
| CN112881738A (en) | Full-automatic biological sample analysis integrated equipment and control method | |
| CN217359218U (en) | Liquid-based film-making equipment | |
| CN212483096U (en) | Liquid-based cell film-making dyeing all-in-one | |
| CN205120676U (en) | Automatic priming device suitable for gas liquid chromatogram - mass spectrography | |
| CN217931701U (en) | Multi-project body fluid analyzer | |
| CN218674435U (en) | Cell film-making dyeing machine | |
| CN218213035U (en) | Preceding processing equipment of limulus reagent sample |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant |