CN216727573U

CN216727573U - Full-automatic refiner

Info

Publication number: CN216727573U
Application number: CN202123388931.8U
Authority: CN
Inventors: 孙磊; 刘永; 李丽; 石松泉; 施其球; 姜杰
Original assignee: Altlebo Suzhou Laboratory Technology Co ltd
Current assignee: Altlebo Suzhou Laboratory Technology Co ltd
Priority date: 2021-12-30
Filing date: 2021-12-30
Publication date: 2022-06-14
Anticipated expiration: 2031-12-30

Abstract

The utility model discloses a full-automatic refiner, comprising: the frame, the pipe support and the cleaning assembly that arrange side by side in the frame, set up in a plurality of centrifuging tubes on the pipe support, fix drive assembly in the frame, with drive assembly fixed connection's homogenate subassembly, homogenate subassembly with centrifuging tube cooperation homogenate. According to the automatic homogenizer, the number and the positions of the samples on the pipe frame are set, the homogenizing assembly can automatically complete cell crushing of the samples, after homogenizing is completed, the homogenizing cutter heads can clean the cutter heads through the cleaning assembly, cross contamination among each group of samples is prevented, the automatic homogenizer is provided with four homogenizing cutter heads, automation can be achieved in the whole process, manual participation is not needed, manual work is liberated, efficiency is improved, and consistency of sample data is guaranteed.

Description

Full-automatic refiner

Technical Field

The utility model relates to the field of cleaning of a refiner, in particular to a full-automatic refiner.

Background

The automatic homogenizer is mainly used for detecting microorganisms in medicines and foods, can break solid, liquid and biological tissues at a high speed to prepare a sample for examination, and replaces a mortar to make the preparation of a test solution simple, rapid and uniform. The internal cutting type homogenizer has a high-strength crushing effect, and the special stainless steel internal and external crushing cutter is driven to rotate at a high speed by the miniature high-speed motor, so that the stirring, emulsifying and crushing effects on various substances are achieved. Different cutters are utilized to crush different cell membranes at different speeds, so that immiscible solid phase, liquid phase and gas phase are instantly, uniformly and finely dispersed and emulsified under the combined action of corresponding mature processes and a proper amount of additives, and a stable high-quality product is finally obtained through high-frequency circulation. Generally, a centrifuge tube is placed on an automatic homogenizer, a homogenizing knife head breaks cells of a sample in the centrifuge tube, and after the breaking is completed, the blade is cleaned.

At present, most of laboratory for testing and detecting the pretreatment of samples manually hold a centrifugal tube carrying the samples to homogenize the samples under a manual homogenizer, which not only wastes manpower, but also has low efficiency and can not ensure the consistency of the homogenization effect of each group of samples. At present, full-automatic homogenizers are available on the market, but the homogenized effect is different, and in addition to the precision control of the homogenizers, the difference of the process technology is more important.

Disclosure of Invention

The utility model overcomes the defects of inconvenient cleaning of a homogenizing cutter head, time and labor waste in the prior art, provides a full-automatic homogenizer, and adopts the following technical scheme in order to achieve the purpose: a fully automatic refiner, comprising: the frame, pipe support and the washing subassembly that arrange side by side in the frame, set up in a plurality of centrifuging tubes on the pipe support, fix drive assembly in the frame, with drive assembly fixed connection's refining assembly, refining assembly with centrifuging tube cooperation refining.

In a preferred embodiment of the present invention, the homogenizing assembly comprises a motor frame, a plurality of motors arranged at the bottom of the motor frame, and a homogenizing cutter head fixedly connected with the rotating ends of the motors.

In a preferred embodiment of the present invention, the driving assembly includes an X-directional slide rail, an X-slider engaged with the X-directional slide rail, a Z-directional slide rail, and a Z-slider engaged with the Z-directional slide rail, the X-directional slide rail is fixed on the rack, the Z-directional slide rail is fixedly connected with the X-slider, and the Z-slider is fixedly connected with the motor rack.

In a preferred embodiment of the utility model, the X-slider and the Z-slide rail are fixed by a connecting block, the connecting block comprises an X-direction fixing plate and a Z-direction fixing plate, the X-direction fixing plate is arranged on the X-slide rail, the X-direction fixing plate is fixedly connected with the X-slider, and the Z-slide rail moves linearly on the X-slide rail along with the X-slider;

the Z-direction fixing plate and the X-direction fixing plate are vertically arranged and fixed through a plurality of right-angle plates, and the Z-direction fixing plate is fixedly connected with the Z-direction sliding rail.

In a preferred embodiment of the present invention, the cleaning assembly comprises three cleaning tanks, which are an ultrasonic cleaning tank, a purified water tank and an organic solvent tank in sequence from a side close to the pipe frame to a side far from the pipe frame.

In a preferred embodiment of the present invention, a plurality of partition plates are disposed inside the ultrasonic cleaning tank to divide the ultrasonic cleaning tank into ultrasonic regions equal in number to the number of the homogenizing cutter heads, and a gap is left between the bottom edge of each partition plate and the bottom of the ultrasonic cleaning tank.

In a preferred embodiment of the present invention, a waste liquid tank is disposed inside the frame, the ultrasonic cleaning tank, the purified water tank and the organic solvent tank are connected to the waste liquid tank through drainage pipes, and each of the drainage pipes is provided with a valve for controlling water flow.

In a preferred embodiment of the present invention, a peristaltic pump is further disposed on the frame, and the cleaning assembly is used for injecting liquid through the peristaltic pump.

The utility model solves the defects in the background technology, and has the following beneficial effects:

according to the automatic homogenizer, the number and the positions of the samples on the pipe frame are set, the homogenizing assembly can automatically complete cell crushing of the samples, after homogenizing is completed, the homogenizing cutter heads can clean the cutter heads through the cleaning assembly, cross contamination among each group of samples is prevented, the automatic homogenizer is provided with four homogenizing cutter heads, automation can be achieved in the whole process, manual participation is not needed, manual work is liberated, efficiency is improved, and consistency of sample data is guaranteed.

Drawings

In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings of the embodiments can be obtained according to the drawings without creative efforts.

FIG. 1 is a schematic view of a fully automatic refiner according to an embodiment of the utility model;

FIG. 2 is another schematic perspective view of a fully automatic refiner of an embodiment of the present invention;

fig. 3 is a schematic diagram of a cleaning assembly of a fully automatic refiner according to an embodiment of the utility model.

The reference numerals are as follows: 001. a frame; 002. a pipe frame; 003. centrifuging the tube; 10. cleaning the assembly; 101. an ultrasonic cleaning tank; 1011. a partition plate; 102. a purified water tank; 103. an organic solvent tank; 20. a drive assembly; 201. an X-direction slide rail; 202. an X slider; 203. a Z-direction slide rail; 204. a Z slider; 205. an X-direction fixing plate; 106. a Z-direction fixing plate; 107. a right-angle plate; 30. a homogenizing assembly; 301. a motor frame; 302. a motor; 303. and (4) a homogenizing cutter head.

Detailed Description

In order that the above objects, features and advantages of the present invention can be more clearly understood, the present invention will be further described in detail with reference to the accompanying drawings and the detailed description, wherein the drawings are simplified schematic drawings and only the basic structure of the present invention is illustrated schematically, so that only the structure related to the present invention is shown, and it is to be noted that the embodiments and features of the embodiments in the present application can be combined with each other without conflict.

In the description of the present application, it is to be understood that the terms "center," "longitudinal," "lateral," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," and the like are used in the orientation or positional relationship indicated in the drawings for convenience in describing the present application and for simplicity in description, and are not intended to indicate or imply that the referenced devices or elements must have a particular orientation, be constructed in a particular orientation, and be operated in a particular manner, and are not to be considered limiting of the scope of the present application. Furthermore, the terms "first," "second," and the like are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first," "second," etc. may explicitly or implicitly include one or more of that feature. In the description of the utility model, the meaning of "a plurality" is two or more unless otherwise specified.

In the description of the present application, it is to be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "connected," and "connected" are to be construed broadly, e.g., as meaning either a fixed connection, a removable connection, or an integral connection; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meaning of the above terms in the present application can be understood by those of ordinary skill in the art through specific situations.

To facilitate an understanding of the utility model, the utility model will now be described more fully with reference to the accompanying drawings. Preferred embodiments of the present invention are shown in the drawings. This invention may, however, be embodied in many different forms and should not be construed as limited to the embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete.

As shown in fig. 1, a full automatic refiner, comprising: frame 001, pipe support 002 and the washing subassembly 10 that arrange side by side on frame 001, set up a plurality of centrifuging tubes 003 on pipe support 002, fix drive assembly 20 in frame 001, with drive assembly 20 fixed connection's homogenate component 30, homogenate component 30 with centrifuging tube 003 cooperation homogenate. The homogenizing assembly 30 comprises a motor frame 301, a plurality of motors 302 arranged at the bottom of the motor frame 301, and a homogenizing cutter head 303 fixedly connected with the rotating ends of the motors 302.

According to the utility model, by setting the number and the positions of the samples on the pipe frame 002, the homogenizing assembly 30 can automatically complete the cell disruption of the samples, after the homogenization is completed, the homogenizing cutter head 303 can clean the homogenizing cutter head 303 through the cleaning assembly 10, so that the cross contamination among each group of samples is prevented, the automatic homogenizer is provided with four homogenizing cutter heads 303, the automation of the whole process can be realized, the manual participation is not needed, the manual work is liberated, the efficiency is improved, and the consistency of sample data is ensured.

As shown in fig. 1-2, in an embodiment of the present invention, the driving assembly 20 includes an X-directional sliding rail 201, an X-sliding block 202 engaged with the X-directional sliding rail 201, a Z-directional sliding rail 203, and a Z-sliding block 204 engaged with the Z-directional sliding rail 203, the X-directional sliding rail 201 is fixed on the rack 001, the Z-directional sliding rail 203 is fixedly connected with the X-sliding block 202, and the Z-sliding block 204 is fixedly connected with the motor frame 301.

Specifically, the X-direction slide rail 201 is fixed on the rack 001, the Z-direction slide rail 203 makes reciprocating linear motion in the X-direction along with the X slider 202, the motor frame 301 is fixed on the Z slider 204, the motor frame 301 makes reciprocating linear motion in the Z-direction along with the Z slider 204, and the motor frame 301 drives the motor 302 and the homogenizing cutter head 303 to make reciprocating motion in the X-direction and the Z-direction so as to send the homogenizing cutter head 303 into the centrifuge tube 003 for homogenizing and send the homogenizing cutter head 303 into the cleaning assembly 10 for automatically cleaning.

The X-direction sliding block 202 and the Z-direction sliding rail 203 are fixed through a connecting block, the connecting block comprises an X-direction fixing plate 205 and a Z-direction fixing plate 206, the X-direction fixing plate 205 is arranged on the X-direction sliding rail 201, the X-direction fixing plate 205 is fixedly connected with the X-direction sliding block 202, and the Z-direction sliding rail 203 moves linearly on the X-direction sliding rail 201 along with the X-direction sliding block 202; the Z-direction fixing plate 206 and the X-direction fixing plate 205 are vertically arranged and fixed through a plurality of right-angle plates 207, and the Z-direction fixing plate 206 is fixedly connected with the Z-direction sliding rail 203.

As shown in fig. 1 and 3, the cleaning assembly includes three cleaning tanks, which are an ultrasonic cleaning tank 101, a purified water tank 102 and an organic solvent tank 103 in sequence from the side close to the pipe frame 002 to the side away from the pipe frame 002.

Particularly, homogenate tool bit 303 stirs the bits in centrifuging tube 003, after the homogenate is accomplished, drive homogenate tool bit 303 to ultrasonic cleaning tank 101 by drive assembly 20 and motor frame 301, wash in proper order in pure water groove 102 and the organic solvent groove 103, earlier will adhere to the material on homogenate tool bit 303 in ultrasonic cleaning tank 101 and clear away, wash in pure water groove 102 again, put into organic solvent with homogenate tool bit 303 at last, dissolve remaining reagent on the homogenate tool bit 303, with ensureing that can not remain reagent again on the homogenate tool bit 303, avoid the cross contamination between the multiunit reagent.

A plurality of partition plates 1011 are provided inside the ultrasonic cleaning tank 101 to divide the ultrasonic cleaning tank 101 into ultrasonic zones equal in number to the homogenizing cutter heads 303, and a gap is left between the bottom edge of the partition plate 1011 and the bottom of the ultrasonic cleaning tank 101.

Here, the ultrasonic cleaning tank 101 is partitioned into small ultrasonic regions by the partition plate 1011, so that the cleaning effect is better while the cleaning frequency is maintained high. And a gap is left between the bottom edge of the partition plate 1011 and the bottom of the ultrasonic cleaning tank 101, so that the wastewater is conveniently discharged.

Not shown in the figure, a waste liquid bucket is arranged inside the frame 001, the ultrasonic cleaning tank 101, the purified water tank 102 and the organic solvent tank 103 are connected with the waste liquid bucket through drainage pipes, and each drainage pipe is provided with a valve for controlling water flow to be discharged.

A peristaltic pump is further arranged on the rack 001, and the cleaning assembly 10 is filled with liquid through the peristaltic pump.

That is to say, annotate the liquid through the peristaltic pump, the rethread drain pipe is discharged, labour saving and time saving and very convenient.

Referring to fig. 1-3, when the present invention works, the working process is as follows:

1. manually placing the weighed centrifuge tube 003 on a tube frame 002;

moving the homogenizing cutter head 303 to the upper part of the first row of centrifuge tubes 003 by an X-direction slide rail 201;

3, moving the homogenizing cutter head 303 downwards to the 15mm position at the lowest part of the centrifugal tube 003 by a Z-direction sliding rail 203; simultaneously starting a peristaltic pump, pumping distilled water into the ultrasonic cleaning tank 101, pumping distilled water into the purified water tank 102, and pumping an organic reagent into the organic solvent tank 103;

4. starting a motor 302 to homogenize;

moving the X slide block 202 to enable the homogenizing cutter head 303 to lean against the wall of the centrifuge tube 003 for 5 seconds, then moving the Z slide block 204 upwards, and moving the homogenizer to a first cleaning tank;

6. moving a homogenizer into an ultrasonic cleaning tank 101, starting ultrasonic waves for about 180 seconds, starting 1000 revolutions per minute, and rotating for 30 seconds;

7. after the ultrasonic treatment is finished, moving the homogenizing cutter head 303 to the upper part, staying for 10 seconds, transversely moving the homogenizing cutter head to the upper part of the purified water tank 102, moving the homogenizing cutter head to the lower part of the purified water tank 102, starting 1000 revolutions per minute, rotating for 30 seconds, and moving the homogenizing cutter head 303 to the upper part and staying for 10 seconds;

8. moving the homogenizing cutter head 303 to the organic solvent tank 103, starting 1000 rpm, rotating for 30 seconds, and moving the homogenizing cutter head 303 to the upper part for 10 seconds;

9. moving the homogenizing cutter head 303 to the position above the second group of centrifuge tubes 003 to enter the next group; meanwhile, distilled water in the ultrasonic cleaning tank 101 and the purified water tank 102 is discharged into a waste liquid barrel, the organic reagent is reserved, and after 4 groups of operation, the organic reagent is discharged.

The above examples only show some embodiments of the present invention, and the description thereof is more specific and detailed, but not to be construed as limiting the scope of the utility model. It should be noted that, for a person skilled in the art, several variations and modifications can be made without departing from the inventive concept, which falls within the scope of the present invention. Therefore, the protection scope of the present patent shall be subject to the appended claims.

Claims

1. A full-automatic refiner, characterized by comprising: the frame, pipe support and the washing subassembly that arrange side by side in the frame, set up in a plurality of centrifuging tubes on the pipe support, fix drive assembly in the frame, with drive assembly fixed connection's refining assembly, refining assembly with centrifuging tube cooperation refining.

2. A fully automatic refiner according to claim 1, wherein: the homogenate subassembly includes the motor frame, set up in a plurality of motors of motor frame bottom, with the homogenate tool bit of the rotatory end fixed connection of motor.

3. A fully automatic refiner according to claim 2, wherein: the driving assembly comprises an X-direction sliding rail, an X-direction sliding block matched with the X-direction sliding rail, a Z-direction sliding rail and a Z-direction sliding block matched with the Z-direction sliding rail, the X-direction sliding rail is fixed on the rack, the Z-direction sliding rail is fixedly connected with the X-direction sliding block, and the Z-direction sliding block is fixedly connected with the motor rack.

4. A fully automatic refiner according to claim 3, wherein: the X-direction sliding rail and the Z-direction sliding rail are fixed through a connecting block, the connecting block comprises an X-direction fixing plate and a Z-direction fixing plate, the X-direction fixing plate is arranged on the X-direction sliding rail, the X-direction fixing plate is fixedly connected with the X-direction sliding rail, and the Z-direction sliding rail moves linearly on the X-direction sliding rail along with the X-direction sliding rail;

5. A fully automatic refiner according to claim 2, wherein: the cleaning assembly comprises three cleaning tanks, wherein the cleaning tanks are close to one side of the pipe frame and far away from one side of the pipe frame, and the ultrasonic cleaning tanks, the purified water tank and the organic solvent tank are sequentially arranged on one side of the pipe frame.

6. A full automatic refiner according to claim 5, wherein: the inside of ultrasonic cleaning tank is provided with a plurality of baffles in order will ultrasonic cleaning tank divide into with homogenate tool bit quantity equals's ultrasonic zone, the base of baffle with ultrasonic cleaning tank's bottom leaves the clearance.

7. A full automatic refiner according to claim 5, wherein: the inside of frame is provided with the waste liquid bucket, ultrasonic cleaning tank the pure water groove and the organic solvent groove pass through drainage pipe with the waste liquid bucket is connected, every all be provided with a valve on the drainage pipe with control water flow discharge.

8. The full-automatic refiner of claim 1, wherein: still be provided with the peristaltic pump in the frame, the washing subassembly passes through the peristaltic pump annotates the liquid.