CN216724854U - Device for inserting carotid artery into experimental rat - Google Patents
Device for inserting carotid artery into experimental rat Download PDFInfo
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- CN216724854U CN216724854U CN202122941737.1U CN202122941737U CN216724854U CN 216724854 U CN216724854 U CN 216724854U CN 202122941737 U CN202122941737 U CN 202122941737U CN 216724854 U CN216724854 U CN 216724854U
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Abstract
A device for intubation of carotid artery of experimental rat comprises an intravascular catheter (1), an extravascular catheter (4) and a built-in guide wire (7), and is characterized in that: the intravascular catheter (1) is connected with an extravascular catheter (4) through a conical fixing knot (3), a built-in guide wire (7) can be placed into the extravascular catheter (1) and the intravascular catheter (4) and can be pulled out, and the extravascular catheter (4) is connected with a medical three-way valve (5). The utility model is used for rat carotid artery intubate, convenient operation easily fixes, improves carotid artery intubate success rate.
Description
Technical Field
The patent of the utility model relates to an utensil for the animal experiments, especially a rat experiment articles for use, specifically speaking are a device for experiment rat carotid artery intubate.
Background
The carotid cannulation of rats is a common experimental procedure in the field of life sciences. The operation of measuring pulmonary artery pressure, collecting blood, administering medicine and the like through a carotid artery cannula is an important means for multidisciplinary research on cardiovascular system, pharmacology, toxicology and the like. Because the carotid artery of a rat is small, the selection and preparation of an arterial catheter are crucial to the success of the operation, the catheter is too soft and is difficult to control and insert, the catheter is too hard and easily penetrates through the vascular tissue, the catheter is too thick and easily punctures or even tears the blood vessel, and the catheter is too thin and easily causes the blockage of the catheter.
At present, most laboratories adopt the rat carotid intubation device self-made by the arterial catheter indwelling needle for human use, but have the following problems: (1) the arterial catheter indwelling needle for the human is not easy to fix and slip after being inserted into the blood vessel; (2) the diameter of the artery indwelling needle is not suitable and is not favorable for operation; (3) the lumen is not easy to keep smooth, and the research process is influenced by easy blockage in the experimental process; (4) the self-made intubation device has unstable performance and quality, which results in poor stability of experimental data.
SUMMERY OF THE UTILITY MODEL
The utility model aims to provide a device for experimental rat carotid artery intubation aiming at the problem of inconvenient pulsatile vessel intubation, so as to improve the success rate of carotid artery intubation and be easy to fix and prevent falling off; the elbow guide wire arranged in the catheter increases the hardness of the hose, is beneficial to operation and cannot puncture blood vessels; the top end of the catheter is designed to be connected with a medical three-way valve so as to facilitate administration, blood sampling or pressure measurement at the same time; in the experimental process, small doses of physiological saline can be intermittently given through the medical three-way valve to prevent the blockage of the tube cavity.
The technical scheme of the utility model as follows:
a device for intubation of carotid artery of experimental rat comprises an intravascular catheter 1, an extravascular catheter 4 and a built-in guide wire 7, and is characterized in that: the intravascular catheter 1 is connected with an extravascular catheter 4 through a conical fixed knot 3, a built-in guide wire 7 can be placed into the extravascular catheter 1 and the extravascular catheter 4 and can be pulled out, and the extravascular catheter 4 is connected with a medical three-way valve 5.
The front end of the intravascular catheter 1 is blunt round, the catheter body is marked with length scales 2, the tail end of the intravascular catheter 1 is connected with an extravascular catheter 4 through a conical fixed knot 3, the outer diameter of the intravascular catheter 1 is 0.64mm +/-0.01 mm, and the inner diameter of the intravascular catheter 1 is 0.31mm +/-0.01 mm.
The top end of the extravascular catheter 4 is connected with a built-in guide wire 7 or a medical three-way valve 5, the tail end of the extravascular catheter 4 is connected with the intravascular catheter 1 through a conical fixed knot 3, the external diameter of the extravascular catheter 4 is 1.02mm +/-0.01 mm, and the internal diameter of the extravascular catheter 4 is 0.61mm +/-0.01 mm.
The small end of the cone-shaped fixing knot 3 is connected with the intravascular catheter 1, the large end of the cone is connected with the extravascular catheter 4, and a groove 10 is designed on the small end of the cone-shaped fixing knot.
The top end of the built-in guide wire 7 is provided with a connecting cap 8 so as to be connected with the extravascular catheter 4, the tail end of the built-in guide wire 7 is provided with an elbow, the length of the elbow can reach the front end of the intravascular catheter 1, and the outer diameter of the built-in guide wire 7 is 0.35 mm.
The medical three-way valve can be detached, one interface of the three-way valve is connected with the top end of the extravascular catheter, the other two interfaces of the three-way valve are connected with the heparin cap, and the interfaces of the three-way valve are matched with the injector nipple and the BL-420S biological signal acquisition and analysis system interface. The medical three-way valve adjusts the interface communicated with the extravascular catheter through different rotation directions of the handle 9, and the handle 9 can be rotated to complete multiple experimental operations.
The intravascular catheter 1 and the extravascular catheter 4 are both made of polyurethane, medical grade PVC or medical grade PP polypropylene products; the core wire of the built-in guide wire 7 is a stainless steel product, and the wire body is made of platinum, stainless steel or tungsten products.
The utility model has the advantages of it is following:
1. the guide wire is arranged in the catheter in the carotid artery intubation process, so that the hardness of the catheter is increased, the control of the blood vessel puncture angle is facilitated, the operation is convenient, the tissue damage is reduced, the intubation success rate is improved, and the guide wire can be pulled out after the catheter in the blood vessel reaches a bottom target blood vessel; 2. the wall of the catheter in the blood vessel is marked with scales, so that the accurate length of the catheter entering the blood vessel can be determined; 3. the conical fixing knot is arranged to facilitate the fixing of the position of the catheter in the blood vessel, and the groove is arranged on the conical fixing knot to facilitate the fixing of the position of the carotid cannula and the fixing knot by a surgical suture to prevent the catheter from slipping; 4. the top end of the extravascular catheter is connected with a medical three-way valve, so that a plurality of experimental operations (administration, blood sampling and blood vessel pressure measurement) can be carried out simultaneously, and the physiological saline can be intermittently given to flush the catheter in the long-time operation process, thereby reducing the possibility of blocking the lumen.
Therefore, the intubation device can improve the success rate of the carotid artery intubation of the rat, reduce tissue damage, has simple intubation operation and less time consumption, and reduces the occurrence of intubation falling and blockage.
Drawings
Fig. 1 is a schematic structural diagram of the present invention.
Detailed Description
The present invention will be further described with reference to the accompanying drawings and examples.
As shown in fig. 1.
A device for intubation of carotid artery of experimental rat is composed of an intravascular catheter 1, an extravascular catheter 4 and an internal guide wire 7. The front end of the intravascular catheter 1 is blunt round, the catheter body is provided with length scales 2, and the intravascular catheter is connected with an extravascular catheter 4 through a conical fixed knot 3. The conical end of the conical fixed knot 3 is connected with the intravascular catheter 1, the bottom end of the conical fixed knot is connected with the extravascular catheter 4, and a groove 10 is arranged on the conical fixed knot 3 to facilitate the clamping of a suture line. The top end of the extravascular conduit 4 is provided with a spiral connecting port 11 which can be connected with a medical three-way valve 5 and also can be connected with a built-in guide wire 7. The medical three-way valve 5 has three ports. One interface is connected with the top interface 11 of the extravascular catheter, and the other two interfaces are connected with the heparin cap 6. The medical three-way valve 5 is provided with a handle 9, and the rotating directions of the handle 9 are different, so that the interfaces communicated with the extravascular catheter are also different. The front end of the built-in guide wire 7 is an elbow, the length of the built-in guide wire can be placed into the front end of the intravascular catheter 1, and the tail end of the built-in guide wire is provided with a connecting cap 8 which can be screwed into a connector 11 at the top end of the extravascular catheter 4.
The utility model discloses when preparation rat carotid cannula model, including following step: and inserting the built-in guide wire into the extravascular catheter to the tail end of the built-in guide wire, and placing the built-in guide wire into the front end of the intravascular catheter, wherein the top end of the built-in guide wire is screwed into the top end of the extravascular catheter through a connecting cap. The intravascular catheter containing the built-in guide wire is inserted into the carotid artery blood vessel of the rat, the position of the carotid intubation is tied together with the conical fixed knot by using a surgical suture, and the carotid intubation is embedded into the groove. After ligation and fixation, the built-in guide wire is pulled out, and the medical three-way valve is screwed into the top end of the extravascular catheter for subsequent experimental operation.
Example (b): carotid catheterization of SD rats
When a rat carotid artery intubation model is manufactured, the built-in guide wire 7 is placed into the extravascular catheter 4 and screwed into the connecting port 11 through the top connecting cap 8 for fixation. The intravascular catheter 1 containing the built-in guide wire 7 is inserted into the carotid artery blood vessel of the rat, and the depth of the blood vessel is clearly inserted through the scale marks 2 on the wall of the intravascular catheter 1. The carotid cannula is tied together with the conical fixing knot 3 by using surgical suture, and the suture is embedded into the groove 10 for fixing. The built-in guide wire 7 is pulled out, one interface of the medical three-way valve 5 is screwed into the top interface of the extravascular catheter, and the other two interfaces of the medical three-way valve are connected with the heparin cap 6. The medical three-way valve 5 can be communicated with the extravascular catheter through different interfaces along with different rotation directions by rotating the handle 9 on the medical three-way valve.
The utility model discloses the part that does not relate to all is the same with prior art or can adopt prior art to realize.
Claims (7)
1. A device for intubation of carotid artery of experimental rat comprises an intravascular catheter (1), an extravascular catheter (4) and a built-in guide wire (7), and is characterized in that: the intravascular catheter (1) is connected with the extravascular catheter (4) through a conical fixing knot (3), the built-in guide wire (7) can be placed into the extravascular catheter (4) and can be pulled out, and the extravascular catheter (4) is connected with a medical three-way valve (5).
2. The device for the carotid intubation of laboratory rats according to claim 1, characterized in that: the front end of the intravascular catheter (1) is in an obtuse circle shape, the catheter body is marked with length scales (2), the tail end of the intravascular catheter is connected with the extravascular catheter (4) through a conical fixing knot (3), the outer diameter of the intravascular catheter (1) is 0.64mm +/-0.01 mm, and the inner diameter of the intravascular catheter is 0.31mm +/-0.01 mm.
3. The device for the carotid intubation of laboratory rats according to claim 1, characterized in that: the top end of the extravascular catheter (4) is connected with a built-in guide wire (7) or a medical three-way valve (5), the tail end of the extravascular catheter (4) is connected with the intravascular catheter (1) through a conical fixing knot (3), the outer diameter of the extravascular catheter (4) is 1.02mm +/-0.01 mm, and the inner diameter of the extravascular catheter (4) is 0.61mm +/-0.01 mm.
4. The device for the carotid intubation of laboratory rats according to any of the claims from 1 to 3, characterized in that: the small end of the cone-shaped fixing knot (3) is connected with the intravascular catheter (1), the large end of the cone is connected with the extravascular catheter (4), and a groove (10) is designed on the small end of the cone-shaped fixing knot.
5. The device for the carotid intubation of laboratory rats according to claim 1 or 3, characterized in that: the top end of the built-in guide wire (7) is provided with a connecting cap (8) so as to be connected with the extravascular catheter (4), the tail end of the built-in guide wire is provided with an elbow, the length of the built-in guide wire can reach the front end of the intravascular catheter (1), and the outer diameter of the built-in guide wire (7) is 0.35 mm.
6. The device for the carotid intubation of laboratory rats according to claim 1, characterized in that: the medical three-way valve (5) is provided with three interfaces, wherein one interface is connected with the top interface of the extravascular catheter (4), and the other two interfaces are connected with the heparin cap; the medical three-way valve adjusts the interface communicated with the extravascular catheter through the different rotation directions of the handle (9) on the medical three-way valve.
7. The device for the carotid intubation of laboratory rats according to claim 1, characterized in that: the intravascular catheter (1) and the extravascular catheter (4) are both made of polyurethane, medical grade PVC or medical grade PP polypropylene products; the core wire of the built-in guide wire (7) is a stainless steel product, and the wire body is made of platinum, stainless steel or tungsten products.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202122941737.1U CN216724854U (en) | 2021-11-29 | 2021-11-29 | Device for inserting carotid artery into experimental rat |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202122941737.1U CN216724854U (en) | 2021-11-29 | 2021-11-29 | Device for inserting carotid artery into experimental rat |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN216724854U true CN216724854U (en) | 2022-06-14 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202122941737.1U Active CN216724854U (en) | 2021-11-29 | 2021-11-29 | Device for inserting carotid artery into experimental rat |
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| CN (1) | CN216724854U (en) |
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2021
- 2021-11-29 CN CN202122941737.1U patent/CN216724854U/en active Active
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