CN216703363U - Ultrasonic spray drying device for curcumin embedding - Google Patents
Ultrasonic spray drying device for curcumin embedding Download PDFInfo
- Publication number
- CN216703363U CN216703363U CN202220183943.2U CN202220183943U CN216703363U CN 216703363 U CN216703363 U CN 216703363U CN 202220183943 U CN202220183943 U CN 202220183943U CN 216703363 U CN216703363 U CN 216703363U
- Authority
- CN
- China
- Prior art keywords
- vacuum pump
- embedding
- ultrasonic
- chamber
- drying chamber
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Images
Landscapes
- Drying Of Solid Materials (AREA)
Abstract
The utility model relates to an ultrasonic spray drying device for curcumin embedding, which comprises a drying chamber (1), wherein an ultrasonic nozzle (2) is arranged at the top of the drying chamber (1), and the ultrasonic nozzle (2) is sequentially connected with a material pipeline (3), a material pump (4) and an ultrasonic embedding system (5); the top of the drying chamber (1) is connected with a first vacuum pump (6), and the lower part of the drying chamber is connected with a second vacuum pump (7); and a material blocking partition plate (102) is arranged at the lower part of the drying chamber (1), and a material collecting chamber (101) at the lower part is isolated. This device adopts the supersound embedding system to replace traditional heating magnetic stirring system, and the embedding rate is high, easy operation, and the parameter is easily controlled, changes the quality of control curcumin embedding thing.
Description
Technical Field
The utility model relates to a drying device, in particular to an ultrasonic spray drying device for curcumin embedding.
Background
Curcumin is one of the components of traditional Chinese medicines such as turmeric, radix curcumae and the like, is a typical II-type medicament in BCS system classification, and has extremely low water solubility and high permeability. Modern pharmacological studies have shown that curculin has pharmacological activities of anti-inflammatory, antioxidant, antitumor, cholagogue, antimutagenic, hypolipidemic, antiatherosclerotic, antidiabetic, antimicrobial, neuroprotective, wound healing and antiproliferative. In addition, the curcumin can be applied to the production of cosmetics by utilizing the effects of antioxidation, anti-inflammation, bacteriostasis, mite killing and the like of the curcumin. However, it is rapidly metabolized in vivo, has low blood concentration in blood, short half-life of drug, is sensitive to alkaline conditions, heat treatment, light, metal ions, enzymes, oxygen and ascorbic acid, and can form many different degradation products such as vanillin, ferulic acid, feruloylmethane, acetone, etc., thereby limiting its clinical use. To solve these problems, the preparation of curcumin as an inclusion compound, a novel drug carrier, has been extensively studied.
The existing spraying method mainly comprises three modes of centrifugal spraying, pressure spraying and airflow spraying. The centrifugal spray type is to atomize the material by centrifugation; the pressure spraying is to atomize the material by using the pressure of a high-pressure pump; the airflow atomizing type utilizes the flow velocity of high-pressure air to atomize materials. With the development of economy and the improvement of requirements, the conventional spraying methods cannot meet the requirements of people, the sizes of the liquid drops sprayed by the conventional spraying methods are not uniform, the materials are not uniform, and the problem of incomplete embedding exists when the conventional spraying methods are used for embedding curcumin.
The existing spray drying equipment mainly adopts high-speed centrifugal spray drying and conventional spray drying, and the drying process does not involve high-temperature air, so that the inactivation, denaturation and the like of materials can be caused. Meanwhile, a large amount of water vapor, compressed air and water are needed in the high-temperature spray drying process, so that great energy consumption and waste are caused, and the development of intensive industry is not facilitated.
SUMMERY OF THE UTILITY MODEL
In order to solve the technical problems, the utility model aims to provide an ultrasonic spray drying device for curcumin embedding without gas heating.
The technical scheme of the utility model is as follows:
an ultrasonic spray drying device for curcumin embedding is characterized in that: the drying device comprises a drying chamber (1), wherein an ultrasonic nozzle (2) is arranged at the top of the drying chamber (1), and the ultrasonic nozzle (2) is sequentially connected with a material pipeline (3), a material pump (4) and an ultrasonic embedding system (5);
the top of the drying chamber (1) is connected with a first vacuum pump (6), and the lower part of the drying chamber is connected with a second vacuum pump (7);
and a material blocking partition plate (102) is arranged at the lower part of the drying chamber (1) and is used for isolating a material collecting chamber (101) at the lower part.
Furthermore, the vacuum degrees of the first vacuum pump (6) and the second vacuum pump (7) are 0.04-0.1 Mpa.
Further, the drying device further comprises an air cooling chamber (8), wherein the air cooling chamber (8) is located between the first vacuum pump (6), the second vacuum pump (7) and the drying chamber (1) and is used for condensing moisture in pipelines connecting the first vacuum pump (6), the second vacuum pump (7) and the drying chamber (1).
Furthermore, an observation window (103) is arranged on the outer wall of the drying chamber (1).
Further, the material collecting chamber (101) is conical, a heat-insulating jacket (9) is annularly arranged outside the material collecting chamber, heat-insulating liquid is arranged in the heat-insulating jacket (9), and heating wires (901) are further arranged in the heat-insulating jacket (9).
Furthermore, a first liquid inlet and a first liquid outlet are further arranged on the heat-insulating jacket (9), a cooling water jacket is arranged outside the first vacuum pump (6) and the second vacuum pump (7), a second liquid inlet and a second liquid outlet are respectively arranged on the cooling water jacket, wherein the first liquid inlet is connected with the second liquid outlet through a first circulating pipe (902), the first liquid outlet is connected with the second liquid inlet through a second circulating pipe (903), and a circulating pump (904) is further arranged on the first circulating pipe (902).
By the scheme, the utility model at least has the following advantages:
the existing spray drying equipment mainly adopts high-speed centrifugal spray drying and conventional spray drying, and the drying process does not involve high-temperature air, so that the inactivation, denaturation and the like of materials can be caused. Meanwhile, a large amount of water vapor, compressed air and water are needed in the high-temperature spray drying process, so that great energy consumption and waste are caused, and the development of intensive industry is not facilitated.
The utility model adopts the ultrasonic embedding system to replace the traditional heating magnetic stirring system, has high embedding rate, simple operation, easily controlled parameters and easier control of the quality of the curcumin embedded substance; the ultrasonic nozzle is adopted for material spraying, so that the material spraying is uniform, and the curcumin embedding substance is completely coated; and the vacuum-pumping drying chamber is adopted, and the principle that the boiling point of liquid is reduced under the vacuum negative pressure state is utilized, so that the solvent can be evaporated from the feed liquid at a low temperature, the damage of the temperature to curcumin in the high-temperature steam drying process is avoided, and the quality of the curcumin inclusion is further improved.
In addition, as the feed liquid is not heated by gas in the drying process, the exhaust gas discharged in the drying process is greatly reduced, the heat loss is reduced, the energy consumption is lower, the production cost is effectively saved, and the pollution to the environment is less.
The two heating modes are adopted to heat the material collecting chamber, the heating wires are adopted to perform electric heating at the initial starting stage, and the heat emitted by the two vacuum pumps is adopted to perform heating at the later stage, so that the device is efficient and energy-saving.
The foregoing description is only an overview of the technical solutions of the present invention, and in order to make the technical solutions of the present invention more clearly understood and to implement them in accordance with the contents of the description, the following detailed description is given with reference to the preferred embodiments of the present invention and the accompanying drawings.
Drawings
FIG. 1 is a schematic structural view of the present invention;
in the figure:
1-a drying chamber; 101-a material collection chamber; 102-a material blocking baffle plate; 103-observation window;
2-ultrasonic wave nozzle; 3-a material pipeline; 4-a material pump; 5-an ultrasonic embedding system;
6-a first vacuum pump; 601-a first vacuum conduit; 7-a second vacuum pump; 701-a second vacuum conduit;
8-an air cooling chamber;
9-heat preservation jacket; 901-heating wires; 902-a first circulation pump; 903-a second circulation pump; 904-circulation pump.
Detailed Description
The following detailed description of embodiments of the present invention is provided in connection with the accompanying drawings and examples. The following examples are intended to illustrate the utility model, but are not intended to limit the scope of the utility model.
Referring to fig. 1, the ultrasonic spray drying device for curcumin embedding according to a preferred embodiment of the present invention includes a drying chamber 1, the drying chamber 1 is a drying chamber 1 with a conventional cylindrical shape, an ultrasonic nozzle 2 is disposed on the top of the drying chamber 1, and the ultrasonic nozzle 2 is sequentially connected to a material pipeline 3, a material pump 4 and an ultrasonic embedding system 5. The ultrasonic embedding system is adopted to replace the traditional heating magnetic stirring system, the embedding rate is high, the operation is simple, the parameters are easy to control, and the quality of the curcumin embedded substance is easier to control; the ultrasonic nozzle is adopted for material spraying, so that the material spraying is uniform, and the curcumin embedding substance is completely coated. The ultrasonic embedding system 5 is generally connected with an ultrasonic controller and a heater, wherein the ultrasonic controller adjusts the frequency of ultrasonic waves, and the heater adjusts the temperature of ultrasonic water bath. The ultrasonic nozzle 2 is also connected with an ultrasonic controller, and the ultrasonic controller adjusts the frequency of the ultrasonic wave to control the spraying amount of the ultrasonic nozzle 2.
The top of the drying chamber 1 is connected with a first vacuum pump 6, the lower part of the drying chamber is connected with a second vacuum pump 7, the drying chamber further comprises an air cooling chamber 8, the air cooling chamber 8 is positioned between the first vacuum pump 6, the second vacuum pump 7 and the drying chamber 1 and is used for condensing moisture in pipelines connected with the first vacuum pump 6, the second vacuum pump 7 and the drying chamber 1, and the vacuum degrees of the first vacuum pump 6 and the second vacuum pump 7 are 0.04-0.1 Mpa. Through the arrangement of the upper vacuum pump and the lower vacuum pump, the upper part and the lower part of the drying chamber are vacuumized, and granulation is facilitated.
A material blocking partition plate 102 is arranged at the lower part of the drying chamber 1, and is used for isolating a material collecting chamber 101 at the lower part, and a valve is generally arranged at the bottom of the material collecting chamber 101 and is used for blanking.
An observation window 103 is arranged on the outer wall of the drying chamber 1, and the observation window 103 is made of transparent glass and used for observing the outside.
The material collecting chamber 101 is conical, the heat preservation jacket 9 is annularly arranged outside the material collecting chamber, heat preservation liquid is arranged in the heat preservation jacket 9, a heating wire 901 is further arranged in the heat preservation jacket 9, and in the initial starting state of the equipment, the heat preservation of the interior is also heated through the heating wire 901, so that the heat preservation of the heat preservation jacket 9 is realized.
Still be provided with first inlet and first liquid outlet on the heat preservation jacket 9, first vacuum pump 6, second vacuum pump 7 is provided with cooling jacket outward, cooling jacket all is provided with second inlet and second liquid outlet, wherein first inlet passes through first circulating pipe 902 and connects the second liquid outlet, first liquid outlet passes through second circulating pipe 903 and connects the second inlet, still be provided with circulating pump 904 on the first circulating pipe 902, after equipment starts a period, two vacuum pumps can generate heat, realize the thermal transport to two vacuum pumps through the effect of two circulating pipes and circulating pump, the realization is to the heat preservation of heat preservation jacket.
The utility model has at least the following advantages:
the existing spray drying equipment mainly adopts high-speed centrifugal spray drying and conventional spray drying, and the drying process does not involve high-temperature air, so that the inactivation, denaturation and the like of materials can be caused. Meanwhile, a large amount of water vapor, compressed air and water are needed in the high-temperature spray drying process, so that great energy consumption and waste are caused, and the development of intensive industry is not facilitated.
The utility model adopts the ultrasonic embedding system to replace the traditional heating magnetic stirring system, has high embedding rate, simple operation, easily controlled parameters and easier control of the quality of the curcumin embedded substance; the ultrasonic nozzle is adopted for material spraying, so that the material spraying is uniform, and the curcumin embedding substance is completely coated; and a vacuumized drying chamber is adopted, and the principle that the boiling point of liquid is reduced under the vacuum negative pressure state is utilized, so that the solvent can be evaporated from the feed liquid under the low-temperature state, the curcumin is prevented from being damaged by the temperature in the high-temperature steam drying process, and the quality of the curcumin inclusion is further improved.
In addition, because the feed liquid is not heated by gas in the drying process, the exhaust gas discharged in the drying process is greatly reduced, the heat loss is reduced, the energy consumption is lower, the production cost is effectively saved, and the pollution to the environment is less.
The two heating modes are adopted to heat the material collecting chamber, the heating wires are adopted to perform electric heating at the initial starting stage, and the heat emitted by the two vacuum pumps is adopted to perform heating at the later stage, so that the device is efficient and energy-saving.
The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention, it should be noted that, for those skilled in the art, many modifications and variations can be made without departing from the technical principle of the present invention, and these modifications and variations should also be regarded as the protection scope of the present invention.
Claims (6)
1. An ultrasonic spray drying device for curcumin embedding is characterized in that: the drying device comprises a drying chamber (1), wherein an ultrasonic nozzle (2) is arranged at the top of the drying chamber (1), and the ultrasonic nozzle (2) is sequentially connected with a material pipeline (3), a material pump (4) and an ultrasonic embedding system (5);
the top of the drying chamber (1) is connected with a first vacuum pump (6), and the lower part of the drying chamber is connected with a second vacuum pump (7);
and a material blocking partition plate (102) is arranged at the lower part of the drying chamber (1) and is used for isolating a material collecting chamber (101) at the lower part.
2. The ultrasonic spray-drying device for curcumin embedding of claim 1, characterized in that: the vacuum degrees of the first vacuum pump (6) and the second vacuum pump (7) are 0.04-0.1 Mpa.
3. The ultrasonic spray-drying device for curcumin embedding of claim 1, characterized in that: the drying device is characterized by further comprising an air cooling chamber (8), wherein the air cooling chamber (8) is located between the first vacuum pump (6), the second vacuum pump (7) and the drying chamber (1) and used for condensing moisture in a pipeline connecting the first vacuum pump (6), the second vacuum pump (7) and the drying chamber (1).
4. The ultrasonic spray-drying device for curcumin embedding according to claim 1, characterized in that: an observation window (103) is arranged on the outer wall of the drying chamber (1).
5. The ultrasonic spray-drying device for curcumin embedding of claim 1, characterized in that: the material collecting chamber (101) is conical, a heat-insulating jacket (9) is annularly arranged outside the material collecting chamber, heat-insulating liquid is arranged in the heat-insulating jacket (9), and a heating wire (901) is further arranged in the heat-insulating jacket (9).
6. An ultrasonic spray drying device for curcumin embedding according to claim 5, characterized in that: the heat-insulation jacket is characterized in that a first liquid inlet and a first liquid outlet are further formed in the heat-insulation jacket (9), cooling water jackets are arranged outside the first vacuum pump (6) and the second vacuum pump (7), a second liquid inlet and a second liquid outlet are formed in each cooling water jacket, the first liquid inlet is connected with the second liquid outlet through a first circulating pipe (902), the first liquid outlet is connected with the second liquid inlet through a second circulating pipe (903), and a circulating pump (904) is further arranged on the first circulating pipe (902).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202220183943.2U CN216703363U (en) | 2022-01-24 | 2022-01-24 | Ultrasonic spray drying device for curcumin embedding |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202220183943.2U CN216703363U (en) | 2022-01-24 | 2022-01-24 | Ultrasonic spray drying device for curcumin embedding |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN216703363U true CN216703363U (en) | 2022-06-10 |
Family
ID=81873473
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202220183943.2U Active CN216703363U (en) | 2022-01-24 | 2022-01-24 | Ultrasonic spray drying device for curcumin embedding |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN216703363U (en) |
-
2022
- 2022-01-24 CN CN202220183943.2U patent/CN216703363U/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN201476472U (en) | Single-cold-trap multi-freeze-drying-bin type microwave vacuum freezing and drying device | |
| CN106839804A (en) | A kind of efficient cooling tower | |
| CN105466174A (en) | Vacuum tube bundle drying machine | |
| CN216703363U (en) | Ultrasonic spray drying device for curcumin embedding | |
| CN101919443B (en) | Absorption type low-temperature drying tower | |
| CN204787649U (en) | Corn is dried and is used vacuum drying machine | |
| CN206881162U (en) | A kind of feed SDPP spray drying device | |
| CN212523089U (en) | Bio-pharmaceuticals is with cold trap case of being convenient for wash | |
| CN208215753U (en) | A kind of modifying plastics particle drying device | |
| CN214436560U (en) | Spray drying tower for bean flour processing | |
| CN111632401A (en) | Equipment and process for extracting fresh plant tissues | |
| CN2650039Y (en) | Vacuum spraying microwave drying system | |
| CN218608056U (en) | Spray drier | |
| CN210773316U (en) | Hinge type continuous vacuum low-temperature freeze dryer | |
| CN209428530U (en) | A kind of fermentation liquid after-treatment device for reducing MK open loop structure and being converted into closed loop configuration | |
| CN219722802U (en) | Spray freezing granulation drying equipment | |
| CN216062049U (en) | High-speed centrifugal spray dryer | |
| CN217311994U (en) | Double-effect energy-saving external circulation vacuum concentrator | |
| CN213747581U (en) | Donkey-hide gelatin product preparation process stoving sterilizing equipment | |
| CN102425925A (en) | Intelligent microwave vacuum continuous drying machine | |
| CN209270853U (en) | Evaporator heat exchange tubulation equipped with auxiliary tube | |
| CN220834143U (en) | Drying equipment for plant extracts | |
| CN215756522U (en) | Energy-saving water distiller for gas boiler | |
| CN103816689B (en) | MVR evaporator | |
| CN219440692U (en) | PVC processing aid pressure type spray drying tower |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant |