CN216678284U

CN216678284U - Full-automatic pipettor

Info

Publication number: CN216678284U
Application number: CN202123037332.1U
Authority: CN
Inventors: 辛博; 陈春林; 赵佳宝
Original assignee: Nanjing Yunshang Chemical Technology Co ltd; Nanjing University
Current assignee: Nanjing Yunshang Chemical Technology Co ltd; Nanjing University
Priority date: 2021-12-06
Filing date: 2021-12-06
Publication date: 2022-06-07
Anticipated expiration: 2031-12-06

Abstract

The utility model discloses a full-automatic pipettor, which comprises a rack, wherein two longitudinal beams which are parallel to each other are arranged on the rack, a cross beam is arranged between the two longitudinal beams, an X-axis sliding block is connected to the cross beam in a sliding manner, and the X-axis sliding block is connected with an X-direction driving mechanism; the Z-axis sliding block is connected with a Z-axis sliding block in a sliding manner and is connected with a Z-direction driving mechanism; the automatic liquid-discharging device comprises a Z-axis sliding block, a gun rack, a sliding table and a pressing motor, wherein the Z-axis sliding block is provided with the gun rack, the sliding table and the Z-axis sliding block are in sliding connection, the pressing motor is arranged above the sliding table, an output shaft of the pressing motor is connected with a pressing screw rod in threaded connection with the sliding table, the sliding table is provided with a knob motor, the gun rack is arranged below the knob motor, and an output shaft of the knob motor is used for being connected with a liquid-discharging button of a liquid-discharging gun; a platform is arranged below the liquid-transfering gun on the frame.

Description

Full-automatic pipettor

Technical Field

The utility model relates to the technical field of pipettors, in particular to a full-automatic pipettor.

Background

A pipette is a device for quantitatively transferring a liquid. The existing pipettors comprise two types, namely a handheld pipette gun and a full-automatic pipettor. The former is a handheld device, the price is low, the operation is simple, but the labor is consumed in a large amount of experiments; the latter is full-automatic liquid-transfering equipment, convenient to use in a large amount of experiments, but the price is expensive, and most range is fixed, and difficult the change, the flexibility is not enough, in order to adapt to multiple experiments, can only purchase many equipment, but the unable mixed use of equipment room again. Therefore, a pipetting device which is flexible to use, wide in application range and moderate in price is urgently needed.

SUMMERY OF THE UTILITY MODEL

The utility model provides a full-automatic pipettor which has the advantages that a pipette gun can be automatically operated to perform liquid transferring operation, the rated liquid transferring amount of the pipette gun can be automatically adjusted, the rated liquid transferring amount of the pipette gun does not need to be manually adjusted, and the automation degree of the liquid transferring operation is greatly improved.

The utility model aims to realize the technical scheme that the full-automatic pipettor comprises a rack, wherein two longitudinal beams which are parallel to each other are arranged on the rack, a cross beam which is vertical to the longitudinal beams is arranged between the two longitudinal beams, an X-axis sliding block is connected onto the cross beam in a sliding manner, and the X-axis sliding block is connected with an X-direction driving mechanism which is used for driving the X-axis sliding block to move on the cross beam;

the Z-axis sliding block is connected with a Z-axis sliding block in a sliding manner, and is connected with a Z-direction driving mechanism for driving the Z-axis sliding block to move on the Z beam;

the automatic liquid transferring device comprises a Z-axis sliding block, a gun rack, a sliding table and a pressing motor, wherein the gun rack is used for installing a liquid transferring gun, the sliding table is in sliding connection with the Z-axis sliding block, the pressing motor is arranged above the sliding table, an output shaft of the pressing motor is connected with a pressing lead screw in threaded connection with the sliding table, the pressing motor is used for driving the sliding table to slide up and down on the Z-axis sliding block, a knob motor is arranged on the sliding table, the gun rack is arranged below the knob motor, and an output shaft of the knob motor is used for being connected with a liquid discharging button of the liquid transferring gun;

a platform is arranged below the liquid-transfering gun on the frame.

The utility model further provides a vision acquisition camera which is fixed on the frame and used for acquiring image information of a digital display window on the liquid-transferring gun.

The utility model further provides the liquid-transferring gun, which comprises a gun head withdrawing fixing pin and a waste gun head collecting box, wherein the gun head withdrawing fixing pin is fixed on the rack, the gun head withdrawing fixing pin is used for pressing a gun head withdrawing button on the liquid-transferring gun, and the waste gun head collecting box is arranged below the gun head withdrawing fixing pin.

The utility model is further arranged in such a way that a new gun head support is arranged on the platform and used for placing the clean liquid-transfering gun head.

The X-direction driving mechanism further comprises a driving chain connected with the X-axis sliding block, the driving chain is supported by two chain wheels arranged on the cross beam, and one chain wheel is connected with an X-direction driving motor used for driving the chain wheel to rotate.

The utility model is further provided that the Z-direction driving mechanism comprises a Z-direction screw rod arranged on the Z beam, the Z-direction screw rod is in threaded connection with the Z-axis sliding block, and the Z-direction screw rod is connected with a Z-direction driving motor used for driving the Z-direction screw rod to rotate.

The utility model is further arranged in such a way that at least two Y-direction sliding rods are arranged at the bottom of the rack and are parallel to the longitudinal beam, Y-direction sliding blocks are connected onto the Y-direction sliding rods in a sliding manner, the platform is installed on the Y-direction sliding blocks, the platform is connected with a driving synchronous belt, the driving synchronous belt is connected through two belt wheels arranged on the rack, and one belt wheel is connected with a Y-direction driving motor.

The utility model is further arranged in that the gun rack is provided with a mounting groove for mounting the pipette, the shape of the mounting groove is matched with the appearance of the pipette, the gun rack is also provided with a special-shaped supporting plate matched with the shape of a handle of the pipette, the gun rack is connected with a compression ring for compressing the pipette, and two ends of the compression ring are connected with the gun rack through buckles.

The utility model is further arranged in such a way that a guide rod parallel to the cross beam is arranged on the rack, a guide sleeve is arranged on the back of the Z beam, and the guide rod penetrates through the guide sleeve.

In conclusion, the beneficial effects of the utility model are as follows:

1. according to the utility model, the Z-axis slide block can drive the liquid-transfering gun to move in the X direction and the Z direction, and the platform can be controlled to move in the Y direction, so that the liquid-transfering gun and a solution vessel placed on the platform can move flexibly and relatively, and the liquid-transfering gun can complete complex liquid-transfering operation; the pressing operation of the liquid-transfering gun is realized by a pressing motor, the sliding table can be pushed to move on the Z beam when the pressing motor rotates, and then the liquid-transfering gun is pressed by a knob motor, so that the liquid-transfering gun can suck liquid or discharge liquid;

2. according to the utility model, the knob motor is connected with the liquid outlet button of the liquid transfer gun, when the rated liquid transfer amount of the liquid transfer gun needs to be adjusted, the rated liquid transfer amount of the liquid transfer gun can be changed by rotating the liquid outlet button on the liquid transfer gun through the knob motor, the adjustment of the rated liquid transfer amount of the liquid transfer gun is automatic, manual adjustment is not needed, and the automation level and the production efficiency of the liquid transfer process are improved;

3. according to the utility model, the vision acquisition camera is arranged for acquiring the image information of the digital display window on the pipetting gun, the digital information of the digital display window on the pipetting gun indicates the current rated pipetting amount of the pipetting gun, when the rated pipetting amount of the pipetting gun is adjusted through the knob motor, the number in the digital display window can change, and the vision analysis and the number identification are carried out on the image information about the digital display window acquired by the vision acquisition camera, so that the rated pipetting amount of the pipetting gun can be converted into a digital signal, the rotation amount of the knob motor is controlled, and the accuracy of the adjustment of the rated pipetting amount of the pipetting gun is improved;

4. according to the utility model, the pipette head withdrawing fixing pin is arranged for automatically withdrawing the pipette head of the pipette, after one pipetting operation is completed, the pipette is controlled to move towards the pipette head withdrawing fixing pin, the pipette head withdrawing button on the pipette is enabled to be abutted against the pipette head withdrawing fixing pin, and the pipette head of the pipette can be withdrawn and fall into the waste pipette head collecting box below; meanwhile, the liquid-transfering gun is controlled to move towards a new gun head placed on the new gun head support, the lower end of the liquid-transfering gun is inserted into the new gun head, the new gun head can be replaced for the liquid-transfering gun, the procedure of replacing the gun head for the liquid-transfering gun can be automatically realized, and the automation degree of the equipment is further improved.

Drawings

FIG. 1 is a schematic diagram of the overall structure of an embodiment of the present invention;

FIG. 2 is a schematic structural diagram of a front view of an embodiment of the present invention;

FIG. 3 is a schematic side view of an embodiment of the present invention;

FIG. 4 is a schematic structural diagram of a bottom view of an embodiment of the present invention;

FIG. 5 is a schematic structural diagram illustrating a mounting manner of a platform according to an embodiment of the present invention;

FIG. 6 is a schematic diagram of the process of analyzing and processing image information in the digital display window of the pipette of the present invention.

In the figure, 1, a frame; 2. a stringer; 3. a cross beam; 4. an X-axis slider; 5. a Z-beam; 6. a Z-axis slide block; 7. A gun rack; 71. mounting grooves; 72. a special-shaped supporting plate; 73. pressing a ring; 8. a sliding table; 9. a pressing motor; 10. pressing the screw rod; 11. a knob motor; 12. a platform; 13. a sprocket; 14. an X-direction driving motor; 15. a Z-direction screw rod; 16. a Z-direction driving motor; 17. a Y-direction sliding rod; 18. a Y-direction sliding block; 19. a pulley; 20. a Y-direction driving motor; 21. a guide bar; 22. a guide sleeve.

In the drawings, some features are hidden or moved to represent the structure, and the specific positional relationship between the features is subject to the description in the specification.

Detailed Description

The following detailed description of embodiments of the utility model refers to the accompanying drawings.

It should be noted that the pipette in the present invention is a commercially available manual pipette for pipetting liquids, and a typical brand thereof is, for example, a Tuo pipette, which has a liquid outlet button and a pipette head withdrawing button, wherein the liquid outlet button can be pressed to discharge the liquid sucked in the pipette, and the pipette head withdrawing button is used to withdraw a detachable pipette head on the pipette. The liquid outlet button can adjust the rated liquid outlet quantity of the liquid transferring gun through rotation, and after the liquid outlet button rotates to a specified position, the liquid transferring quantity of the liquid transferring gun is a fixed numerical value every time. The liquid-transfering gun has a digital display window, on which the digital information is mechanical digital code for indicating the current rated liquid-transfering quantity of the liquid-transfering gun.

Example (b): referring to fig. 1-5, a full-automatic pipette includes a frame 1, two longitudinal beams 2 parallel to each other are disposed on the frame 1, a cross beam 3 perpendicular to the longitudinal beams 2 is disposed between the two longitudinal beams 2, an X-axis slider 4 is slidably connected to the cross beam 3, and the X-axis slider 4 is connected to an X-direction driving mechanism for driving the X-axis slider 4 to move on the cross beam 3. The X-direction driving mechanism comprises a driving chain connected with the X-axis sliding block 4, the driving chain is supported by two chain wheels 13 arranged on the cross beam 3, and one chain wheel 13 is connected with an X-direction driving motor 14 used for driving the chain wheel 13 to rotate. After the X-direction driving motor 14 works, the X-axis sliding block 4 is driven by the driving chain to slide along the cross beam 3. In the drawings, the specific location of the drive chain is not given, but does not affect the understanding of the overall scheme.

In order to increase the rigidity of the Z beam 5 and reduce the vibration of the Z beam 5, a guide rod 21 parallel to the cross beam 3 is arranged on the frame 1, a guide sleeve 22 is arranged on the back surface of the Z beam 5, the guide rod 21 penetrates through the guide sleeve 22, and the guide rod 21 and the guide sleeve 22 support and guide the movement of the Z beam 5, so that the movement rigidity of the Z beam 5 is improved.

The X-axis sliding block 4 is provided with a Z beam 5, the Z beam 5 extends above the X-axis sliding block 4, the Z beam 5 is connected with a Z-axis sliding block 6 in a sliding mode, and the Z-axis sliding block 6 is connected with a Z-axis driving mechanism used for driving the Z-axis sliding block 6 to move on the Z beam 5. The Z-direction driving mechanism comprises a Z-direction screw rod 15 arranged on the Z beam 5, the Z-direction screw rod 15 is in threaded connection with the Z-axis sliding block 6, and the Z-direction screw rod 15 is connected with a Z-direction driving motor 16 used for driving the Z-direction screw rod 15 to rotate. After the Z-direction driving motor 16 works, the Z-axis sliding block 6 is driven to slide up and down on the Z beam 5 through the Z-direction screw rod 15.

And a gun rack 7, a sliding table 8 and a pressing motor 9 are arranged on the Z-axis sliding block 6. Gun rack 7 is used for installing the liquid-transfering gun, be equipped with the mounting groove 71 that is used for installing the liquid-transfering gun on gun rack 7, the shape and the liquid-transfering gun appearance of mounting groove 71 match, still be equipped with the special-shaped layer board 72 that matches with liquid-transfering gun handle shape on gun rack 7, the liquid-transfering gun can be by fine fixed after placing in mounting groove 71, is connected with clamping ring 73 on gun rack 7 and is used for compressing tightly the liquid-transfering gun, is connected through the buckle between the both ends of clamping ring 73 and gun rack 7. And the sliding table 8 is in sliding connection with the Z-axis sliding block 6, and the sliding direction is vertical. The pressing motor 9 is arranged above the sliding table 8, an output shaft of the pressing motor 9 is connected with a pressing screw rod 10 in threaded connection with the sliding table 8, the pressing motor 9 is used for driving the sliding table 8 to slide up and down on the Z-axis sliding block 6, and the pressing motor 9 drives the sliding table 8 to slide up and down on the Z-axis sliding block 6 through the pressing screw rod 10 after working. A knob motor 11 is arranged on the sliding table 8, the gun rack 7 is arranged below the knob motor 11, and after the liquid-transfering gun is fixed on the gun rack 7, an output shaft of the knob motor 11 is connected with a liquid-discharging button of the liquid-transfering gun.

The liquid suction and liquid outlet processes of the liquid-transferring gun are realized by pressing the motor 9, the pressing motor 9 drives the sliding table 8 to slide up and down, so that the knob motor 11 is driven to move, the pressing degree of a liquid outlet button on the liquid-transferring gun is changed, and the liquid outlet and liquid suction processes of the liquid-transferring gun are controlled.

After the knob motor 11 works, the liquid outlet button on the liquid transfer gun is driven to rotate, so that the single liquid transfer gun of the liquid transfer gun is changed. It should be noted that when the rated liquid displacement amount of the liquid displacement gun is changed by the knob motor 11, the height of the liquid outlet button on the liquid displacement gun is changed, and at this time, the sliding block needs to be controlled by a corresponding distance by pressing the motor 9, so as to ensure the connection between the output shaft of the knob motor 11 and the liquid outlet button of the liquid displacement gun.

The full-automatic pipettor in the embodiment of the utility model further comprises a visual acquisition camera which is fixed on the rack 1 and is used for acquiring image information of a digital display window on the pipette. When the rated liquid transfer amount of the liquid transfer gun needs to be adjusted, the liquid transfer gun should be moved to a position right opposite to the vision acquisition camera through the X-direction driving motor 14 and the Z-direction driving motor 16 so that the vision acquisition camera can acquire image information of a digital display window on the liquid transfer gun. After the image information of the digital display window is collected, the image information is uploaded to an additional upper computer for image processing and analysis, the analysis process refers to fig. 6, the image information is converted into digital information and then output to a control system of the knob motor 11 and the pressing motor 9 for controlling the rotation amount of the knob motor 11 and the pressing motor 9, and therefore the rated liquid moving amount of the liquid moving gun is accurately controlled to be adjusted to a designated value. The analysis and recognition of the images uses existing techniques.

A platform 12 is arranged below the liquid-transferring gun on the frame 1, and the platform 12 is used for placing a solution vessel. Because above-mentioned liquid-transfering gun only has the motion degree of freedom of two directions in X direction and Z direction, consequently, the bottom of frame 1 is equipped with two at least Y to slide bar 17, Y to slide bar 17 with longeron 2 is parallel, Y has Y to slider 18 to slide bar 17 go up sliding connection, platform 12 is installed on Y to slider 18, platform 12 is connected with the drive hold-in range, and the bottom at platform 12 is passed through the bolt fastening at the both ends of hold-in range, the drive hold-in range is connected through two band pulleys 19 that set up in frame 1, is connected with Y on one of them band pulley 19 to driving motor 20. After the Y-direction driving motor 20 works, the platform 12 is driven by the driving timing belt to slide along the Y-direction sliding rod 17, and in the drawing, the specific position of the driving timing belt is not shown, but the understanding of the whole scheme is not affected. Through the cooperation that platform 12 and pipetting gun removed, can realize the triaxial of pipetting gun relative to platform 12 and remove the work of getting by can realize complicated liquid.

In order to realize automation of replacement of the pipette tip, the full-automatic pipette in the embodiment of the utility model further comprises a pipette tip withdrawing fixed pin, a waste pipette tip collecting box and a new pipette tip support, wherein the pipette tip withdrawing fixed pin is fixed on the rack 1, the pipette tip withdrawing fixed pin is used for pressing a pipette tip withdrawing button on the pipette tip, and the waste pipette tip collecting box is arranged below the pipette tip withdrawing fixed pin. The new gun head support is arranged on the platform 12 and used for placing clean pipette heads. After completing one pipetting operation, controlling the pipetting gun to move towards the fixed pin for withdrawing the gun head and enabling a button for withdrawing the gun head on the pipetting gun to be abutted against the fixed pin for withdrawing the gun head, so that the gun head of the pipetting gun can be withdrawn and fall into a waste gun head collecting box below; meanwhile, the liquid-transfering gun is controlled to move towards a new gun head placed on the new gun head support, the lower end of the liquid-transfering gun is inserted into the new gun head, the new gun head can be replaced for the liquid-transfering gun, the procedure of replacing the gun head for the liquid-transfering gun can be automatically realized, and the automation degree of the equipment is further improved.

The foregoing is only a preferred embodiment of the present invention, and it should be noted that, for those skilled in the art, various changes and modifications can be made without departing from the inventive concept of the present invention, and these changes and modifications are all within the scope of the present invention.

Claims

1. The full-automatic pipettor is characterized by comprising a rack (1), wherein two longitudinal beams (2) which are parallel to each other are arranged on the rack (1), a cross beam (3) which is perpendicular to the longitudinal beams (2) is arranged between the two longitudinal beams (2), an X-axis sliding block (4) is connected onto the cross beam (3) in a sliding manner, and the X-axis sliding block (4) is connected with an X-direction driving mechanism which is used for driving the X-axis sliding block (4) to move on the cross beam (3);

a Z-axis slider (5) is arranged on the X-axis slider (4), a Z-axis slider (6) is connected onto the Z-axis slider (5) in a sliding manner, and the Z-axis slider (6) is connected with a Z-direction driving mechanism for driving the Z-axis slider (6) to move on the Z-axis slider (5);

the automatic liquid transferring gun is characterized in that a gun rack (7), a sliding table (8) and a pressing motor (9) are mounted on the Z-axis sliding block (6), the gun rack (7) is used for mounting a liquid transferring gun, the sliding table (8) is in sliding connection with the Z-axis sliding block (6), the pressing motor (9) is arranged above the sliding table (8), an output shaft of the pressing motor (9) is connected with a pressing lead screw (10) in threaded connection with the sliding table (8), the pressing motor (9) is used for driving the sliding table (8) to slide up and down on the Z-axis sliding block (6), a knob motor (11) is arranged on the sliding table (8), the gun rack (7) is arranged below the knob motor (11), and an output shaft of the knob motor (11) is used for being connected with a liquid discharging button of the liquid transferring gun;

a platform (12) is arranged below the liquid-transfering gun on the frame (1).

2. The fully automatic pipette according to claim 1, further comprising a vision-capturing camera fixed to the frame (1), the vision-capturing camera being configured to capture image information of a digital display window on the pipette.

3. The full-automatic pipette according to claim 1, further comprising a tip withdrawing fixing pin fixed to the frame (1) and used tip collecting box provided below the tip withdrawing fixing pin for pressing a tip withdrawing button on the pipette.

4. The fully automatic pipette according to claim 3, wherein a new tip holder is provided on the platform (12) for placing a clean pipette tip.

5. The fully automatic pipette according to claim 1, wherein the X-direction drive mechanism comprises a drive chain connected to the X-axis slide (4), the drive chain being supported by two sprockets (13) provided on the cross beam (3), wherein one sprocket (13) is connected to an X-direction drive motor (14) for driving the sprocket (13) to rotate.

6. The fully automatic pipette according to claim 1, wherein the Z-direction driving mechanism comprises a Z-direction screw rod (15) arranged on the Z beam (5), the Z-direction screw rod (15) is in threaded connection with the Z-axis slider (6), and a Z-direction driving motor (16) for driving the Z-direction screw rod (15) to rotate is connected to the Z-direction screw rod (15).

7. The fully automatic pipette according to claim 1, wherein at least two Y-direction sliding rods (17) are arranged at the bottom of the rack (1), the Y-direction sliding rods (17) are parallel to the longitudinal beam (2), Y-direction sliding blocks (18) are connected onto the Y-direction sliding rods (17) in a sliding manner, the platform (12) is mounted on the Y-direction sliding blocks (18), a driving synchronous belt is connected onto the platform (12), the driving synchronous belt is connected through two belt wheels (19) arranged on the rack (1), and a Y-direction driving motor (20) is connected onto one belt wheel (19).

8. The fully automatic pipette according to claim 1, wherein a mounting groove (71) for mounting a pipette is formed in the gun rack (7), the shape of the mounting groove (71) is matched with the shape of the pipette, a special-shaped supporting plate (72) matched with the shape of a handle of the pipette is further arranged on the gun rack (7), a pressing ring (73) is connected to the gun rack (7) and used for pressing the pipette, and two ends of the pressing ring (73) are connected with the gun rack (7) through a buckle.

9. The fully automatic pipette according to claim 1, wherein a guide rod (21) parallel to the cross beam (3) is arranged on the frame (1), a guide sleeve (22) is arranged on the back of the Z-beam (5), and the guide rod (21) passes through the guide sleeve (22).