CN216678272U

CN216678272U - Kit based on exosome draws

Info

Publication number: CN216678272U
Application number: CN202220011527.4U
Authority: CN
Inventors: 徐锐; 潘莉; 王白云
Original assignee: Suzhou Aibaode Biotechnology Co ltd
Current assignee: Suzhou Aibaode Biotechnology Co ltd
Priority date: 2022-01-05
Filing date: 2022-01-05
Publication date: 2022-06-07
Anticipated expiration: 2032-01-05

Abstract

The utility model belongs to the field of exosome extraction, in particular to a kit based on exosome extraction, which comprises a box body and a placing groove, wherein a reagent rack is arranged in the box body, a guide block is arranged on the outer side of the reagent rack, a slide rail is connected on the inner side of the guide block, the bottom of the reagent rack is connected with a lifting rod, the lateral side of the lifting rod is connected with a lifting mechanism, the placing groove is arranged in the middle of the reagent rack, the lateral side of the placing groove is provided with a fixed seat, and the outer side of the fixed seat is provided with a fixed mechanism; the reagent rack is provided with the lifting mechanism, the reagent rack in the equipment is adjusted at different heights so as to facilitate visual selection and taking of internal reagents, the taking and placing efficiency is effectively improved, the observation operation is facilitated, the situation of taking errors is prevented, the reagents can be clamped and fixed conveniently, the reagents are stably fixed in the placing grooves through the pressing of the pressing blocks, and the arrangement of the multiple groups of placing grooves is beneficial to storage of multiple groups of reagents.

Description

Kit based on exosome draws

Technical Field

The utility model relates to the field of kits, in particular to a kit based on exosome extraction.

Background

The exosome is a small membrane vesicle with the diameter of 30-150nm containing complex RNA and protein, and is a disc vesicle with the diameter of 40-100nm at present, various cells can secrete the exosome under normal and pathological states, the exosome is mainly derived from a multivesicular body formed by invagination of intracellular lysosome particles, and the multivesicular body is released into extracellular matrix after fusion of the multivesicular body outer membrane and a cell membrane, and a kit needs to be used for participating in an extraction process in the extraction experiment process.

The kit on the existing market has the problems that most of the kits cannot conveniently take internal reagents, the types of the reagents cannot be observed conveniently, the reagents are inconvenient to take, and the reagents cannot be taken conveniently and stably and have certain influence on use.

Therefore, a kit based on exosome extraction is proposed to address the above problems.

SUMMERY OF THE UTILITY MODEL

In order to compensate prior art's not enough, solved most can not conveniently carry out taking of inside reagent in the kit, and be not convenient for observe the reagent kind, take inconvenience to the stable of the reagent of not being convenient for is accomodate, has the problem of certain influence to the use.

The technical scheme adopted by the utility model for solving the technical problems is as follows: the utility model relates to a kit based on exosome extraction, which comprises a kit body and a placing groove, wherein a reagent rack is arranged in the kit body, a guide block is arranged on the outer side of the reagent rack, a slide rail is connected to the inner side of the guide block, a lifting rod is connected to the bottom of the reagent rack, a lifting mechanism is connected to the side of the lifting rod, the placing groove is formed in the middle of the reagent rack, a fixed seat is arranged on the side of the placing groove, and a fixing mechanism is arranged on the outer side of the fixed seat.

Preferably, the reagent rack forms a sliding structure through the guide block and the sliding rail, and the guide block is symmetrically arranged about the central axis of the reagent rack.

Preferably, the lifting mechanism comprises a connecting rod, a rotating piece and an electric shaft, the end part of the connecting rod is connected with the rotating piece, and the side of the rotating piece is connected with the electric shaft.

Preferably, the lifting rod forms a lifting structure through the rotating part and the box body, and the rotating part forms a transmission structure through the electric shaft and the lifting rod.

Preferably, the fixing mechanism comprises a pressing block, a connecting shaft, a control piece, a transmission piece and a rotating rod, the connecting shaft penetrates through the end of the pressing block, the control piece is connected to the outer side of the connecting shaft, the transmission piece is connected to the inner side of the control piece, and the rotating rod penetrates through the end of the transmission piece.

Preferably, the pressing block forms a rotating structure with the control piece through the connecting shaft, and the control piece forms a transmission structure with the fixed seat through the transmission piece.

The utility model has the advantages that:

1. the utility model is provided with a lifting mechanism, firstly, the top cover is opened in a sliding way, the internal reagent can be taken conveniently, then, the bottom lifting rod is controlled to lift through the rotary transmission of the rotating piece, the top reagent rack can be flexibly and conveniently controlled to lift, the internal reagent rack of the equipment can be adjusted in different heights so as to facilitate the visual selection and taking of the internal reagent, the taking and placing efficiency is effectively improved, the observation operation is facilitated, the wrong taking is prevented, meanwhile, the reagent rack can be lifted and taken along the sliding rail through the outer side guide block, the reagent rack can be directly taken out from the box body, the proper operation can be carried out according to different use requirements, and the reagent rack which can be disassembled and assembled can be efficiently and conveniently replaced or cleaned, the applicability and the sanitation of the equipment are improved, the use is facilitated, and the overall operation is convenient, the guide block and the slide rail can effectively assist in dismounting the reagent rack, and can assist in lifting and stabilizing the bottom lifting rod, so that the situation that the inner reagent rack is displaced during movement is prevented, and the use stability is ensured;

2. the reagent bottle positioning device is provided with the fixing mechanism, the outer control piece is pulled to be limited to rotate along the top of the fixing seat and move in a small range through the transmission piece and the rotating rod, the end pressing block can be pressed downwards to be adjusted in a rotating mode around the connecting shaft, so that the pressing block can be conveniently and stably tilted, the pressing block is separated from a reagent bottle in the placing groove, the internal reagent can be conveniently taken and placed, otherwise, the reagent can be conveniently and quickly clamped and fixed, the reagent can be stably fixed in the placing groove through pressing of the pressing block, multiple groups of placing grooves can be beneficial to storage of multiple groups of reagents, the taking operation is convenient, the reagent can be fixed when the reagent bottle positioning device is not used, the use stability of the device is greatly improved, and the whole use stability and safety are beneficial.

Drawings

In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to these drawings without inventive exercise.

FIG. 1 is a schematic cross-sectional perspective view of an embodiment;

FIG. 2 is a schematic perspective view of a lifting mechanism according to an embodiment;

FIG. 3 is a schematic perspective view of a second fixing mechanism according to an embodiment;

in the figure: 1. a box body; 2. a reagent rack; 3. a guide block; 4. a slide rail; 5. a lifting rod; 6. a lifting mechanism; 601. a connecting rod; 602. a rotating member; 603. an electric shaft; 7. a placement groove; 8. a fixed seat; 9. a fixing mechanism; 901. briquetting; 902. a connecting shaft; 903. a control member; 904. a transmission member; 905. and (4) rotating the rod.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

Example one

Referring to fig. 1-2, a kit based on exosome extraction comprises a kit body 1, a reagent rack 2, a guide block 3, a slide rail 4, a lifting rod 5, a lifting mechanism 6, a placing groove 7, a fixed seat 8 and a fixing mechanism 9, wherein the reagent rack 2 is arranged in the kit body 1, the guide block 3 is arranged on the outer side of the reagent rack 2, the slide rail 4 is connected to the inner side of the guide block 3, the lifting rod 5 is connected to the bottom of the reagent rack 2, and the lifting mechanism 6 is connected to the side of the lifting rod 5;

the reagent rack 2 forms a sliding structure through the guide block 3 and the sliding rail 4, and the guide block 3 is symmetrically arranged about the central axis of the reagent rack 2, so that the reagent rack 2 can be disassembled and assembled efficiently and conveniently, the applicability and the sanitation of equipment are improved, and the use is facilitated;

the lifting mechanism 6 comprises a connecting rod 601, a rotating piece 602 and an electric shaft 603, wherein the end of the connecting rod 601 is connected with the rotating piece 602, and the side of the rotating piece 602 is connected with the electric shaft 603;

lifter 5 constitutes elevation structure through between rotating member 602 and the box body 1, and rotating member 602 constitutes transmission structure through between electronic axle 603 and the lifter 5, and the inside reagent frame 2 of equipment carries out not co-altitude mixture control so that make things convenient for the selection directly perceived of inside reagent and take, effectively improves and gets and put efficiency.

Example two

Referring to fig. 1 and 3, in a first comparative example, as another embodiment of the present invention, a placing groove 7 is formed in the middle of a reagent rack 2, a fixing seat 8 is disposed at the side of the placing groove 7, and a fixing mechanism 9 is disposed at the outer side of the fixing seat 8;

the fixing mechanism 9 comprises a pressing block 901, a connecting shaft 902, a control element 903, a transmission element 904 and a rotating rod 905, wherein the connecting shaft 902 penetrates through the end part of the pressing block 901, the control element 903 is connected to the outer side of the connecting shaft 902, the transmission element 904 is connected to the inner side of the control element 903, and the rotating rod 905 penetrates through the end part of the transmission element 904;

briquetting 901 passes through to constitute rotating-structure between connecting axle 902 and the control member 903, and control member 903 passes through to constitute transmission structure between driving medium 904 and the fixing base 8 to this is convenient carries out the operation of getting of inside reagent and puts, otherwise can conveniently carry out the centre gripping of reagent fixed.

The working principle is that firstly, the top cover is opened in a sliding manner, the operation of taking the internal reagent can be conveniently carried out, then the bottom lifting rod 5 is controlled to lift through the rotary transmission of the rotary piece 602, the top reagent rack 2 can be flexibly and conveniently controlled to lift, the reagent rack 2 in the equipment can be adjusted in different heights so as to facilitate the visual selection and taking of the internal reagent, the efficiency of taking and placing is effectively improved, the operation of observation is facilitated, the error taking is prevented, meanwhile, the reagent rack 2 can lift and take along the slide rail 4 through the outer side guide block 3, the reagent rack 2 can be directly taken out from the interior of the box body 1, the proper operation can be carried out according to different use requirements, and the reagent rack 2 which can be disassembled and assembled can be efficiently and conveniently replaced or cleaned, the applicability and the sanitation of the equipment are improved, and the use is facilitated, the whole operation is convenient, the guide block 3 and the slide rail 4 can effectively assist in dismounting the reagent rack 2, and can assist in lifting and stabilizing the bottom lifting rod 5, so that the displacement of the inner reagent rack 2 during movement is prevented, and the use stability is ensured;

later pulling outside control 903, make it rotate and small amplitude removes along 8 tops of fixing base through driving medium 904 and bull stick 905 restriction, can push down tip briquetting 901 and make it rotate the regulation around connecting axle 902, make briquetting 901 perk with this convenient stable, make briquetting 901 and the inside reagent bottle of standing groove 7 separate, with this convenient operation of getting of carrying out inside reagent, otherwise can conveniently carry out the centre gripping of reagent fixed, make reagent stable through briquetting 901 pressure move fixed with in the inside of standing groove 7, the setting of multiunit standing groove 7 can do benefit to depositing of multiunit reagent, and the simple operation of taking, can carry out the fixing of reagent when not using, the stability in use of equipment has been improved greatly, do benefit to whole stability and safety that uses.

In the description herein, references to the description of "one embodiment," "an example," "a specific example" or the like are intended to mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the utility model. In this specification, the schematic representations of the terms used above do not necessarily refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.

The foregoing shows and describes the general principles, essential features, and advantages of the utility model. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, which are described in the specification and illustrated only to illustrate the principle of the present invention, but that various changes and modifications may be made therein without departing from the spirit and scope of the present invention, which fall within the scope of the utility model as claimed.

Claims

1. A kit based on exosome extraction, which is characterized in that: including box body (1) and standing groove (7), the inside of box body (1) is provided with reagent frame (2), and the outside of reagent frame (2) is provided with guide block (3) to the inboard of guide block (3) is connected with slide rail (4), the bottom of reagent frame (2) is connected with lifter (5), and the avris of lifter (5) is connected with elevating system (6), the middle part in reagent frame (2) is seted up in standing groove (7), and the avris of standing groove (7) is provided with fixing base (8), and the outside of fixing base (8) is provided with fixed establishment (9).

2. An exosome extraction-based kit according to claim 1, characterised in that: reagent frame (2) constitute sliding construction through between guide block (3) and slide rail (4), and guide block (3) set up about the axis symmetry of reagent frame (2).

3. An exosome extraction-based kit according to claim 1, characterised in that: elevating system (6) are including connecting rod (601), rotating member (602) and electronic axle (603), the end connection of connecting rod (601) has rotating member (602), and the avris of rotating member (602) is connected with electronic axle (603).

4. An exosome extraction-based kit according to claim 3, characterised in that: the lifting rod (5) forms a lifting structure with the box body (1) through the rotating piece (602), and the rotating piece (602) forms a transmission structure with the lifting rod (5) through the electric shaft (603).

5. An exosome extraction-based kit according to claim 1, characterised in that: fixed establishment (9) have run through connecting axle (902) including briquetting (901), connecting axle (902), control (903), driving medium (904) and bull stick (905), the tip of briquetting (901) has run through connecting axle (902), and the outside of connecting axle (902) is connected with control (903), the inboard of control (903) is connected with driving medium (904), and the tip of driving medium (904) has run through bull stick (905).

6. An exosome extraction-based kit according to claim 5, characterised in that: the pressing block (901) and the control piece (903) form a rotating structure through the connecting shaft (902), and the control piece (903) and the fixed seat (8) form a transmission structure through the transmission piece (904).