CN216669647U - Nano flow type detector for detecting cells - Google Patents

Abstract

The utility model discloses a nano-flow type detector for detecting cells, which comprises a nano-flow type detector body, a display screen and a detection port, wherein a protection mechanism is arranged outside the detection port, and the protection mechanism comprises a clamping strip, a shade, a shielding plate and cleaning sponge. The utility model relates to a nano flow type detector for detecting cells, which belongs to the technical field of biological detection.

Description

Nano flow type detector for detecting cells

Technical Field

The utility model relates to the technical field of biological detection, in particular to a nano flow type detector for detecting cells.

Background

The nano-flow type detector is an advanced single-particle, multi-parameter and high-flux nano-particle quantitative characterization developed based on a sheath-flow single-molecule fluorescence detection technology. The nano flow type detector covers the dead zone of particle size detection below 200nm of the traditional flow type cytometer, covers the characterization of natural biological nano particles such as nano particles, subcellular structures, bacteria, viruses, extracellular vesicles (exosomes) and the like, and opens a window leading to the nano world for the flow type detection technology. The nano-flow detector can realize the particle size, the distribution and the particle concentration of single nano-particles (7-1000 nm). However, traditional nanometer STREAMING detector is when using, mostly all place in detecting the mouth through handheld STREAMING pipe and detect, this kind of mode can only singly detect at every turn, and need artifical handheld operation again when detecting, lead to detection efficiency slow down, simultaneously, because of lacking safeguard measure, lead to the back that finishes at every turn detecting, be stained with the dust on the detector in detecting the mouth easily, also can adhere to the dust on the display of nanometer STREAMING detector in addition, be unfavorable for next detection operation.

SUMMERY OF THE UTILITY MODEL

The utility model mainly aims to provide a nano-flow detector for detecting cells, which can effectively solve the problems in the background technology.

In order to achieve the purpose, the utility model adopts the technical scheme that:

the utility model provides a detect nanometer STREAMING detector of cell, includes nanometer STREAMING detector body, display screen and detection mouth, the outside of detecting the mouth is equipped with protection machanism, protection machanism is including card strip, shade, sunshade and clean sponge, the inside of detecting the mouth is equipped with the mechanism of getting ready, the mechanism of getting ready includes protruding seat, the seat of getting ready, sleeve, connection pad, rolling disc, compression spring, location dop and fender ring.

Preferably, the opening both sides of detection mouth are fixed mounting respectively has the card strip, the spout that corresponds with the card strip is seted up respectively to shade inner wall both sides, just the shade passes through card strip slidable mounting on nanometer STREAMING detector body.

Preferably, the position fixed mounting in the outer wall left side of shade has the sunshade, just the sunshade corresponds with the display screen, fixed mounting has clean sponge on the inside wall of sunshade.

Preferably, a protruding seat is fixedly mounted on the inner bottom surface of the opening of the detection port, a groove is formed in the top surface of the protruding seat, a movable groove is formed in the bottom surface of the groove, and positioning grooves are formed in two sides of the inner wall of the movable groove respectively.

Preferably, the top surface fixed mounting who goes up the appearance seat has a plurality of sleeve with mode fixed mounting of annular permutation, just the top surface fixed mounting who goes up the appearance seat has the connection pad, the connection pad is located the recess, the top surface still fixed mounting of connection pad has the rolling disc, just the rolling disc is located the activity inslot.

Preferably, a plurality of spring grooves corresponding to the sleeves are formed in the outer surface of the rotating disc in an annular array mode, a retaining ring is fixedly mounted at the notch of each spring groove, a compression spring is fixedly mounted on the bottom surface of the spring groove, a positioning clamping head is fixedly mounted at the front end of each compression spring, and the positioning clamping head penetrates through the retaining ring and is located in the positioning groove.

Compared with the prior art, the utility model has the following beneficial effects:

according to the utility model, through the arranged protection mechanism, after the nano-flow type detector body is used, the detection port is masked by the mask, so that the influence of dust entering the detection port on next detection is avoided, and when the mask is used each time, the display screen is cleaned by the cleaning sponge on the shielding plate, and the arranged sample loading mechanism can store a plurality of flow type tubes to be detected at one time, and detect the next tube in a rotating and positioning manner after each detection is finished, so that the whole detection efficiency is improved while the manual operation is liberated, and the sample loading detection operation is realized.

Drawings

FIG. 1 is a schematic view of the overall structure of the present invention;

FIG. 2 is a schematic view of the overall structure of the nano-flow detector body according to the present invention;

FIG. 3 is a schematic structural view of a card strip and a projection base of the present invention on a nano-flow meter body;

FIG. 4 is an enlarged sectional view of the boss of the present invention;

FIG. 5 is a rear view of the overall construction of the guard mechanism of the present invention;

fig. 6 is a schematic structural disassembly diagram of the loading mechanism of the utility model.

In the figure: 1. a nano-flow detector body; 2. a protection mechanism; 3. a display screen; 4. a detection port; 5. a sample loading mechanism; 6. clamping the strip; 7. a boss base; 8. a groove; 9. a movable groove; 10. positioning a groove; 11. masking; 12. a chute; 13. a shutter; 14. cleaning the sponge; 15. a sample loading seat; 16. a sleeve; 17. a connecting disc; 18. rotating the disc; 19. a spring slot; 20. a compression spring; 21. positioning the chuck; 22. and (4) a baffle ring.

Detailed Description

In order to make the technical means, the creation characteristics, the achievement purposes and the effects of the utility model easy to understand, the utility model is further described with the specific embodiments.

As shown in fig. 1-6, a nano-flow detector for detecting cells comprises a nano-flow detector body 1, a display screen 3 and a detection port 4, wherein a protection mechanism 2 is arranged outside the detection port 4, the protection mechanism 2 comprises a clamping strip 6, a shade 11, a shading plate 13 and a cleaning sponge 14, a sample loading mechanism 5 is arranged inside the detection port 4, and the sample loading mechanism 5 comprises a boss 7, a sample loading seat 15, a sleeve 16, a connecting disc 17, a rotating disc 18, a compression spring 20, a positioning chuck 21 and a retaining ring 22.

As shown in fig. 3-5, in this embodiment, in order to avoid dust entering the detection port 4 to affect the next detection, the two sides of the opening of the detection port 4 are respectively and fixedly installed with a card strip 6, the two sides of the inner wall of the mask 11 are respectively and fixedly installed with a chute 12 corresponding to the card strip 6, the mask 11 is slidably installed on the nano-flow type detector body 1 through the card strip 6, the left side part of the outer wall of the mask 11 is fixedly installed with a shield 13, the shield 13 corresponds to the display screen 3, the inner side wall of the shield 13 is fixedly installed with a cleaning sponge 14, after the nano-flow type detector body 1 completes the detection of cells, the mask 11 is manually installed on the nano-flow type detector body 1 and covers the detection port 4, when the operation is performed, the mask 11 is installed in a top-to-bottom manner, and the chutes 12 formed on the two sides of the inner wall of the mask 11 are aligned with the card strip 6, make card strip 6 insert in spout 12, at the installation of shade 11 and cover at the in-process that detects mouth 4, the clean sponge 14 of installation on the inside wall of shade 11 left side wall sunshade 13 will clear up display screen 3 on the nano-flow formula detector body 1 to when taking off shade 11 from nano-flow formula detector body 1, clean sponge 14 will also clear up display screen 3, avoid the dust to adhere to on display screen 3 with this, and prevent that the dust from entering into and detecting mouth 4.

As shown in fig. 2, 4 and 6, in this embodiment, in order to improve the overall detection efficiency, a protrusion base 7 is fixedly installed on the inner bottom surface of the opening of the detection port 4, a groove 8 is formed on the top surface of the protrusion base 7, a movable groove 9 is formed on the bottom surface of the groove 8, positioning grooves 10 are respectively formed on two sides of the inner wall of the movable groove 9, a plurality of sleeves 16 are fixedly installed on the top surface of the sample loading base 15 in an annular array manner, a connecting disc 17 is fixedly installed on the top surface of the sample loading base 15, the connecting disc 17 is located in the groove 8, a rotating disc 18 is also fixedly installed on the top surface of the connecting disc 17, the rotating disc 18 is located in the movable groove 9, a plurality of spring grooves 19 corresponding to the sleeves 16 are formed on the outer surface of the rotating disc 18 in an annular array manner, a retaining ring 22 is fixedly installed at the notch of each spring groove 19, a compression spring 20 is fixedly installed on the inner bottom surface of each spring groove 19, and the front end of the compression spring 20 is fixedly provided with a positioning dop 21, the positioning dop 21 passes through the retaining ring 22 and is positioned in the positioning groove 10, when in use, the flow tube to be detected is sequentially inserted into the sleeve 16 arranged on the top surface of the sample loading seat 15, when the cell detection in the flow tube corresponding to the detection tube in the detection port 4 is finished, the sample loading seat 15 is rotated, at the moment, the connecting disc 17 arranged on the bottom surface of the sample loading seat 15 drives the rotating disc 18 to rotate in the movable groove 9 arranged on the bottom surface of the groove 8, when the rotating disc 18 rotates in the movable groove 9, the positioning dop 21 is extruded, the compression spring 20 retracts in the spring groove 19, and drives the positioning dop 21 to leave the positioning groove 10 and retract to the spring groove 19 through the positioning dop 21, so that the positioning dop 21 abuts against the inner wall of the movable groove 9, after rotating to a certain degree, the next positioning clamp 21 will not abut against the inner wall of the movable groove 9 any more, and the compression spring 20 in the spring groove 19 will perform an extending operation, and will abut the positioning clamp 21 into the positioning groove 10 to complete the rotational positioning, at this time, the sample loading seat 15 will rotate by a corresponding angle, and the flow tube in the sleeve 16 installed on the sample loading seat 15 corresponding to the positioning clamp 21 will be located below the detection tube, and then the detection is performed, so that the cells in the flow tube in the sleeve 16 on the sample loading seat 15 can be sequentially detected by continuously rotating the sample loading seat 15, and the detection efficiency is greatly improved by this way.

While the utility model has been described in detail with reference to the foregoing embodiments, it will be understood by those skilled in the art that various changes may be made and equivalents may be substituted for elements thereof or for parts thereof without departing from the scope of the utility model.

Claims (6)

1. A nano-flow detector for detecting cells is characterized in that: including nano-flow formula detector body (1), display screen (3) and detection mouth (4), the outside of detecting mouth (4) is equipped with protection machanism (2), protection machanism (2) are including card strip (6), shade (11), sunshade (13) and clean sponge (14), the inside of detecting mouth (4) is equipped with the mechanism of drawing a design (5), the mechanism of drawing a design (5) is including protruding seat (7), the seat of drawing a design (15), sleeve (16), connection pad (17), rolling disc (18), compression spring (20), location dop (21) and fender ring (22).

2. The nanoflow detector according to claim 1, wherein the detector comprises: the opening both sides of detecting opening (4) are fixed mounting respectively have card strip (6), spout (12) that correspond with card strip (6) are seted up respectively to shade (11) inner wall both sides, just shade (11) are through card strip (6) slidable mounting on nanometer STREAMING detector body (1).

3. The nanoflow detector according to claim 2, wherein the detector further comprises: the utility model discloses a screen, including shade (11), outer wall left side position fixed mounting have sunshade board (13), just sunshade board (13) correspond with display screen (3), fixed mounting has clean sponge (14) on the inside wall of sunshade board (13).

4. The nano-flow meter for detecting cells according to claim 3, wherein: the bottom surface fixed mounting has protruding seat (7) in the opening of detection mouth (4), just the top surface of protruding seat (7) is seted up flutedly (8), movable groove (9) have been seted up to the bottom surface of recess (8), constant head tank (10) have been seted up respectively to the inslot wall both sides in movable groove (9).

5. The nano-flow meter for detecting cells according to claim 4, wherein: go up the top surface fixed mounting of appearance seat (15) has a plurality of sleeve (16) with mode fixed mounting of annular permutation, just the top surface fixed mounting of going up appearance seat (15) has connection pad (17), connection pad (17) are located recess (8), the top surface of connection pad (17) is fixed mounting still has rolling disc (18), just rolling disc (18) are located movable groove (9).

6. The nano-flow meter for detecting cells according to claim 5, wherein: spring groove (19) that a plurality of and sleeve (16) correspond are seted up with annular permutation's mode on the surface of rolling disc (18), just the notch department fixed mounting of spring groove (19) has fender ring (22), the inslot bottom fixed mounting of spring groove (19) has compression spring (20), just the front end fixed mounting of compression spring (20) has location dop (21), location dop (21) pass and keep off ring (22) and are located constant head tank (10).

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