CN216558412U - Be used for freezing of bio-pharmaceuticals material, novel heat transfer structure for thawing apparatus - Google Patents
Be used for freezing of bio-pharmaceuticals material, novel heat transfer structure for thawing apparatus Download PDFInfo
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- CN216558412U CN216558412U CN202123113370.0U CN202123113370U CN216558412U CN 216558412 U CN216558412 U CN 216558412U CN 202123113370 U CN202123113370 U CN 202123113370U CN 216558412 U CN216558412 U CN 216558412U
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Abstract
The utility model discloses a novel heat exchange structure for a biological pharmaceutical material freezing and unfreezing device, which comprises a heat exchange bin and also comprises: the heat exchange sleeve part is arranged in the heat exchange bin and used for heat exchange between the biopharmaceutical material and a heat exchange medium, and the heat exchange wall part is arranged on the inner wall of the heat exchange bin and used for increasing the heat exchange area of the structure; and install in the sealing top cap at the top of heat transfer storehouse guarantees that the bio-pharmaceuticals material has even technology processing operational environment in structural range, realizes more even efficient heat transfer process, uses this structure moreover, and the equipment realizes compactification design more easily, reduces the factory building requirement, promotes the productivity.
Description
Technical Field
The utility model relates to a novel heat exchange structure for a biological pharmaceutical material freezing and thawing device.
Background
At present, domestic biopharmaceutical companies and scientific research institutions use direct contact flat plate or air supply internal circulation type equipment to freeze or thaw biopharmaceutical materials.
The method comprises the following steps of putting a disposable freezing storage bag or a container with specifications, which is filled with the biopharmaceutical materials, on a direct contact type flat plate, introducing a heat exchange medium (refrigerant or secondary refrigerant) into the flat plate, and exchanging heat with the biopharmaceutical materials in the container or the disposable freezing storage bag through the flat plate so as to achieve the purpose of freezing or thawing; or the disposable barrel-shaped container or the regular container filled with the biopharmaceutical materials is placed into an air supply internal circulation mode for freezing, through the mode, the heat exchange between air and a heat exchange medium is accelerated inside to obtain low-temperature or high-temperature air, and the purpose of quick freezing or thawing is achieved through an air forced convection blowing mode.
SUMMERY OF THE UTILITY MODEL
The utility model aims to provide a novel heat exchange structure for a device for freezing and unfreezing a biopharmaceutical material, which ensures that the biopharmaceutical material has a uniform process treatment working environment in the structural range, realizes a more uniform and efficient heat exchange process, and by using the structure, the device can be more easily compactly designed, the requirements of a workshop are reduced, and the productivity is improved.
The technical scheme for realizing the purpose is as follows: a be used for freezing of bio-pharmaceuticals material, novel heat transfer structure is used to thawing apparatus, includes the heat transfer storehouse, still includes: the heat exchange sleeve part is arranged in the heat exchange bin and used for heat exchange between the biopharmaceutical material and a heat exchange medium, and the heat exchange wall part is arranged on the inner wall of the heat exchange bin and used for increasing the heat exchange area of the structure; and the sealing top cover is arranged at the top of the heat exchange bin.
Preferably: the heat exchange sleeve part comprises a stainless steel spiral pipe, a plurality of stainless steel pipelines and a first inlet/outlet, the stainless steel spiral pipe is arranged inside the heat exchange bin, the side face of the lower end of the stainless steel spiral pipe is communicated with one end of each stainless steel pipeline, the first inlet/outlet is formed in the other end of each stainless steel pipeline, the other end of each stainless steel pipeline penetrates through the sealing top cover, and the first inlet/outlet is located above the sealing top cover.
Preferably: the heat exchange wall part comprises a jacket, a jacket connecting pipe, a jacket interface and a second inlet/outlet, the jacket is installed on the inner wall of the heat exchange bin, one side of the upper end of the stainless steel spiral pipe is communicated with one end of the jacket connecting pipe, the jacket interface is arranged at the other end of the jacket connecting pipe, the jacket interface is communicated with the jacket, the second inlet/outlet is arranged on the outer side of the lower end of the jacket, and the second inlet/outlet penetrates through the outer wall of the heat exchange bin.
Preferably: the shape of the stainless steel pipelines can be adjusted to be round, rectangular or square by matching with the stainless steel spiral pipe.
Preferably: the stainless steel spiral pipe is internally provided with a first pipe sleeve, a second pipe sleeve and a third pipe sleeve in sequence from outside to inside.
The utility model has the beneficial effects that: through installing stainless steel spiral pipe and a plurality of stainless steel pipeline and first business turn over/export, can provide great heat transfer area, realize the even heat transfer of bio-pharmaceuticals material, heat exchange efficiency has been improved, thereby production cycle has been shortened, through installing the clamp cover, press from both sides the cover connecting pipe, press from both sides cover interface and second business turn over/export, flow in the spiral pipe and in the clamp cover through heat transfer medium, can provide more even heat transfer region, thereby realize the even heat transfer of liquid bio-pharmaceuticals material, can cooperate the stainless steel spiral pipe to adjust to circular, rectangle or square through setting up the shape of stainless steel pipeline, the stainless steel spiral pipe of different specifications and the vertical heat transfer sleeve pipe of different specifications, can realize multiple compound mode, thereby adapt to the heat transfer storehouse of different specifications, through set gradually first pipe box, second pipe and second business turn over/export in the inside of stainless steel spiral pipe, The second pipe sleeve and the third pipe sleeve improve the uniformity of heat exchange.
Drawings
FIG. 1 is a schematic structural view of the present invention;
FIG. 2 is a top view of the present invention;
fig. 3 is an internal structure of a stainless steel spiral tube of the present invention.
Reference numerals: 1. stainless steel pipeline; 2. a stainless steel spiral tube; 3. a jacket; 4. a heat exchange bin; 5. sealing the top cover; 6. a first inlet/outlet port; 7. a jacket connecting pipe; 8. a jacket interface; 9. a second inlet/outlet port; 10. a first pipe sleeve; 11. a second pipe sleeve; 12. a third pipe sleeve.
Detailed Description
The technical scheme of the utility model is clearly and completely described in the following with reference to the accompanying drawings. In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc., indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of description and simplicity of description, but do not indicate or imply that the device or element being referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus, should not be construed as limiting the present invention. Furthermore, the terms "first," "second," and "third" are used for descriptive purposes only and are not to be construed as indicating or implying a relative importance.
The utility model will be further explained with reference to the drawings.
Example one
The structure of the common direct contact type flat plate is fixed in shape, the working space occupation ratio is large, the equipment adopting the structure is generally large in size, heavy and generally incapable of moving, the temperature of the equipment which is generally close to the flat plate or an air supply outlet is uniform due to structural limitation, the temperature fluctuation of the equipment which is far away from the flat plate or the air supply outlet is large, the temperature difference of different areas in the working space is large, and the difference of the biopharmaceutical materials among batches is remarkable, referring to fig. 1 to 3, the novel heat exchange structure for the equipment for freezing and unfreezing the biopharmaceutical materials comprises a heat exchange bin 4, a heat exchange sleeve part, a heat exchange wall part and a sealing top cover 5, wherein the heat exchange sleeve part is arranged inside the heat exchange bin 4 and is used for exchanging heat between the biopharmaceutical materials and a heat exchange medium, and the heat exchange wall part is arranged on the inner wall of the heat exchange bin 4 and is used for improving the heat exchange area of the structure; the sealing top cover 5 is arranged at the top of the heat exchange bin 4.
Heat transfer sleeve part includes stainless steel spiral pipe 2 and a plurality of stainless steel pipeline 1 and first business turn over/export 6, stainless steel spiral pipe 2 is installed in the inside of heat transfer storehouse 4, the lower extreme side of stainless steel spiral pipe 2 communicates the one end of stainless steel pipeline 1, the other end of stainless steel pipeline 1 is provided with first business turn over/export 6, sealed top cap 5 is passed to the other end of stainless steel pipeline 1, first business turn over/export 6 is located the top of sealed top cap 5, can provide great heat transfer area, realize the even heat transfer of bio-pharmaceuticals material, the heat exchange efficiency is improved, thereby production cycle has been shortened.
The heat exchange wall part comprises a jacket 3, a jacket connecting pipe 7, a jacket interface 8 and a second inlet/outlet 9, the jacket 3 is arranged on the inner wall of the heat exchange bin 4, one side of the upper end of the stainless steel spiral pipe 2 is communicated with one end of the jacket connecting pipe 7, the other end of the jacket connecting pipe 7 is provided with the jacket interface 8, the jacket interface 8 is communicated with the jacket 3, the second inlet/outlet 9 is arranged on the outer side of the lower end of the jacket 3, the second inlet/outlet 9 penetrates through the outer wall of the heat exchange bin 4, and the heat exchange medium flows in the spiral pipe and the jacket, so that a more uniform heat exchange area can be provided, and uniform heat exchange of the liquid bio-pharmaceutical material is realized.
The shape of a plurality of stainless steel pipelines 1 can be adjusted to be circular, rectangular or square by matching with the stainless steel spiral pipe 2, and the stainless steel spiral pipes with different specifications and the vertical heat exchange sleeves with different specifications can realize various combination modes so as to adapt to the heat exchange bins with different specifications.
The stainless steel spiral pipe 2 is internally provided with a first pipe sleeve 10, a second pipe sleeve 11 and a third pipe sleeve 12 from outside to inside in sequence, so that the heat exchange uniformity is improved.
The working principle is as follows: firstly, a stainless steel spiral pipe 2, a plurality of stainless steel pipelines 1, a jacket 3, a jacket connecting pipe 7 and a jacket interface 8 are installed inside a heat exchange bin 4 according to requirements, then a biopharmaceutical material to be thawed is placed inside the heat exchange bin 4, a sealing top cover 5 is covered, during heat exchange, a heat exchange medium is poured from a first inlet/outlet 6, the heat exchange medium flows from the stainless steel pipeline 1, the stainless steel spiral pipe 2, the jacket connecting pipe 7 and the jacket 3 in sequence, the biopharmaceutical material is outside the pipe, heat exchange is realized in the flowing process, and uniform heat exchange of the biopharmaceutical material is realized due to the fact that the stainless steel spiral pipe provides a large heat exchange area, so that the heat exchange efficiency is improved, the production period is shortened, and the problem that the biopharmaceutical material in the same batch is uneven due to different batch specifications is avoided.
The above embodiments are provided only for illustrating the present invention and not for limiting the present invention, and those skilled in the art can make various changes and modifications without departing from the spirit and scope of the present invention, and therefore all equivalent technical solutions should also fall within the scope of the present invention, and should be defined by the claims.
Claims (5)
1. The utility model provides a be used for freezing of bio-pharmaceuticals material, novel heat transfer structure is used to thawing apparatus, includes heat transfer storehouse (4), its characterized in that: further comprising:
the heat exchange sleeve part is arranged in the heat exchange bin (4) and is used for exchanging heat between the biopharmaceutical material and a heat exchange medium;
the heat exchange wall part is arranged on the inner wall of the heat exchange bin (4) and is used for increasing the heat exchange area of the structure; and
and the sealing top cover (5) is arranged at the top of the heat exchange bin (4).
2. The novel heat exchange structure for a biopharmaceutical material freezing and thawing apparatus of claim 1, wherein: the heat exchange sleeve part comprises a stainless steel spiral pipe (2), a plurality of stainless steel pipelines (1) and a first inlet/outlet (6), the stainless steel spiral pipe (2) is installed inside the heat exchange bin (4), the side face of the lower end of the stainless steel spiral pipe (2) is communicated with one end of the stainless steel pipeline (1), the other end of the stainless steel pipeline (1) is provided with the first inlet/outlet (6), the other end of the stainless steel pipeline (1) penetrates through the sealing top cover (5), and the first inlet/outlet (6) is located above the sealing top cover (5).
3. The novel heat exchange structure for a biopharmaceutical material freezing and thawing apparatus of claim 2, wherein: the heat exchange wall comprises a jacket (3), a jacket connecting pipe (7), a jacket connector (8) and a second inlet/outlet (9), the jacket (3) is installed on the inner wall of the heat exchange bin (4), one side of the upper end of the stainless steel spiral pipe (2) is communicated with one end of the jacket connecting pipe (7), the other end of the jacket connecting pipe (7) is provided with the jacket connector (8), the jacket connector (8) is communicated with the jacket (3), the second inlet/outlet (9) is arranged on the outer side of the lower end of the jacket (3), and the second inlet/outlet (9) penetrates through the outer wall of the heat exchange bin (4).
4. The novel heat exchange structure for a biopharmaceutical material freezing and thawing apparatus of claim 2, wherein: the shape of the stainless steel pipelines (1) can be adjusted to be round, rectangular or square by matching with the stainless steel spiral pipe (2).
5. The novel heat exchange structure for a biopharmaceutical material freezing and thawing apparatus of claim 2, wherein: the stainless steel spiral pipe (2) is internally provided with a first pipe sleeve (10), a second pipe sleeve (11) and a third pipe sleeve (12) in sequence from outside to inside.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202123113370.0U CN216558412U (en) | 2021-12-13 | 2021-12-13 | Be used for freezing of bio-pharmaceuticals material, novel heat transfer structure for thawing apparatus |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202123113370.0U CN216558412U (en) | 2021-12-13 | 2021-12-13 | Be used for freezing of bio-pharmaceuticals material, novel heat transfer structure for thawing apparatus |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN216558412U true CN216558412U (en) | 2022-05-17 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202123113370.0U Active CN216558412U (en) | 2021-12-13 | 2021-12-13 | Be used for freezing of bio-pharmaceuticals material, novel heat transfer structure for thawing apparatus |
Country Status (1)
| Country | Link |
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| CN (1) | CN216558412U (en) |
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2021
- 2021-12-13 CN CN202123113370.0U patent/CN216558412U/en active Active
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