CN216550454U

CN216550454U - Pretreatment device for nucleic acid detection

Info

Publication number: CN216550454U
Application number: CN202122755637.XU
Authority: CN
Inventors: 李晓仟; 吴梦淇; 张红丽
Original assignee: Pingliang Kongtong Traditional Chinese Medicine Hospital
Current assignee: Pingliang Kongtong Traditional Chinese Medicine Hospital
Priority date: 2021-11-11
Filing date: 2021-11-11
Publication date: 2022-05-17
Anticipated expiration: 2031-11-11

Abstract

The utility model belongs to the technical field of nucleic acid detection, and particularly relates to pretreatment equipment for nucleic acid detection, which comprises an apparatus main body, wherein a water bath is arranged on the left side of the apparatus main body, a test tube rack is arranged in the middle of the water bath, a communicating port is arranged on the left side inside the water bath, a first sealing cover is arranged at the top of the water bath, a mixing cabin is arranged on the right side of the apparatus main body, a mixer is arranged inside the mixing cabin, a fixing groove is arranged in the middle of the mixer, a second sealing cover is arranged at the top of the mixing cabin, a control panel is arranged below the mixing cabin, and an apparatus motor is arranged at the bottom end of the apparatus main body; according to the pretreatment equipment for nucleic acid detection, the water bath can be used for effectively inactivating the detection sample in the test tube, the mixer can be used for synchronously mixing the detection sample and the detection solvent while the inactivation is finished, and the inactivation water in the water bath can be conveniently added and replaced by using the combined port and the connecting port.

Description

Pretreatment device for nucleic acid detection

Technical Field

The utility model belongs to the technical field of nucleic acid detection, and particularly relates to pretreatment equipment for nucleic acid detection.

Background

Coronavirus is a large-scale virus family, known to cause more serious diseases such as cold, middle east respiratory syndrome and severe acute respiratory syndrome, and novel coronavirus is a new strain of coronavirus which has never been found in human bodies before, nucleic acid detection operation needs to be carried out on suspected patients when the novel coronavirus is detected and treated, during nucleic acid detection, a sample in a test tube needs to be inactivated in the first step, and in the prior art, the test tube is placed in a water bath for inactivation.

The original nucleic acid detection is usually performed by inactivating and then intensively storing the inactivated nucleic acid, and then transporting the nucleic acid to a laboratory, adding a detection solvent to a sample, and performing sample detection, however, because the intermediate time interval is long, the sample is in an external environment for a long time after being inactivated, and if sample protection is not performed, the detection effect of the sample is likely to be affected, and even secondary infection of the sample is likely to affect the accuracy of the nucleic acid detection.

SUMMERY OF THE UTILITY MODEL

In order to solve the problems in the prior art, the utility model provides a pretreatment device for nucleic acid detection, which has the characteristics of convenient use, simple operation and good detection effect.

In order to achieve the purpose, the utility model provides the following technical scheme: the utility model provides a nucleic acid detects uses pre-processing apparatus, includes the device main part, device main part left side is provided with the water bath, install the test-tube rack in the middle of the water bath, the inside left side of water bath is provided with the mouth of ally oneself with, first sealed lid is installed at water bath top, device main part right side is provided with the hybrid chamber, hybrid chamber internally mounted has the blender, be provided with the fixed slot in the middle of the blender, the sealed lid of second is installed at the hybrid chamber top, the hybrid chamber below is provided with control panel, device main part left side still is provided with the connector, device main part bottom is provided with the device motor, device motor back is provided with power source, the power source bottom is provided with the base.

As a preferable technical solution of the present invention, the water bath is disposed inside the device main body, and a constant temperature heating system is disposed at the bottom of the water bath.

As a preferable technical solution of the present invention, the communication port is disposed on an inner wall of a left side of the water bath, the connection port is connectable to an external water pipe, and the connection port is intercommunicated with an inside of the water bath through the communication port.

In a preferred embodiment of the present invention, the mixer is installed at the bottom of the middle of the mixing chamber, and the fixing groove can fix the test tube containing the nucleic acid test sample in the mixer.

In a preferred embodiment of the present invention, the first and second sealing covers are mounted on a top surface of the apparatus main body, and the first and second sealing covers can seal the insides of the water bath and the mixing chamber, respectively.

As a preferred technical solution of the present invention, the water bath, the mixer and the control panel are electrically connected to the motor of the apparatus, and the power interface is capable of connecting to an external power source and supplying power to the motor of the apparatus.

As a preferred technical scheme of the utility model, the base is arranged at four corners of the bottom of the motor of the device and is made of rubber shock-absorbing materials.

Compared with the prior art, the utility model has the beneficial effects that: according to the pretreatment equipment for nucleic acid detection, the water bath can be used for effectively inactivating the detection sample in the test tube, the mixer can be used for synchronously mixing the detection sample and the detection solvent in a very short time while the inactivation is finished, the time for storing the sample outside is reduced while the next detection procedure is conveniently carried out, the possibility that the detection result is influenced due to the pollution of the sample is reduced, the accuracy of the detection result is ensured, the inactivation water in the water bath can be conveniently added and replaced by using the combined port and the connecting port, and the operation efficiency of the device is ensured.

Drawings

The accompanying drawings, which are included to provide a further understanding of the utility model and are incorporated in and constitute a part of this specification, illustrate embodiments of the utility model and together with the description serve to explain the principles of the utility model and not to limit the utility model. In the drawings:

FIG. 1 is a schematic structural view of the present invention;

FIG. 2 is a schematic top view of the present invention;

FIG. 3 is a schematic view of the back structure of the present invention;

FIG. 4 is a schematic bottom view of the present invention;

in the figure: 1. a device main body; 2. a water bath kettle; 3. a test tube rack; 4. a communication port; 5. a first sealing cover; 6. a mixing chamber; 7. a mixer; 8. fixing grooves; 9. a second sealing cover; 10. a control panel; 11. a connecting port; 12. a device motor; 13. a power interface; 14. a base.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

Examples

Referring to fig. 1-4, the present invention provides the following technical solutions: a pretreatment device for nucleic acid detection comprises a device main body 1, wherein a water bath pot 2 is arranged on the left side of the device main body 1, a test tube rack 3 is arranged in the middle of the water bath pot 2, a communicating hole 4 is arranged on the left side inside the water bath pot 2, a first sealing cover 5 is arranged at the top of the water bath pot 2, a mixing cabin 6 is arranged on the right side of the device main body 1, a mixer 7 is arranged inside the mixing cabin 6, a fixing groove 8 is arranged in the middle of the mixer 7, a second sealing cover 9 is arranged at the top of the mixing cabin 6, a control panel 10 is arranged below the mixing cabin 6, a connecting hole 11 is also arranged on the left side of the device main body 1, a device motor 12 is arranged at the bottom end of the device main body 1, a power supply interface 13 is arranged at the back of the device motor 12, a base 14 is arranged at the bottom of the power supply interface 13, when the pretreatment device is used, an external power supply is firstly connected with the device motor 12 through the power supply interface 13, then an external water pipe is connected and communicated with the water bath pot 2 through the connecting hole 11 and a certain amount of water is injected into the water bath pot 2, then utilize the constant temperature heating system of 2 bottoms of control panel 10 control water bath to heat its inside water, later put into the sample of gathering and put into water bath 2 and fix on test-tube rack 3 after the sealing in the test tube, then cover first sealed lid 5 and carry out the inactivation operation, take out the test tube and instil into the testing solvent after the deactivation is accomplished, then directly put into mixing chamber 6 and utilize blender 7 to mix can, can directly carry out the next process of nucleic acid testing after the mixture is accomplished, therefore, the high-speed automatic analyzer is very convenient, when having improved the efficiency that the accounting detected, still reduced the sample because of the outside reason pollution influences the possibility of nucleic acid testing result, the accuracy that the nucleic acid detected has been guaranteed.

Specifically, as shown in fig. 1 and 2, in this embodiment, the water bath 2 is disposed inside the device main body 1, and the bottom of the water bath 2 is provided with a constant temperature heating system, so as to ensure the inactivation capability of the device on the sample.

Specifically, as shown in fig. 1 and fig. 2, in this embodiment, the communication port 4 is disposed on the inner wall of the left side of the water bath kettle 2, the connection port 11 can be connected with an external water pipe, and the connection port 11 can be communicated with the inside of the water bath kettle 2 through the communication port 4, so that the water inside the water bath kettle 2 can be conveniently injected and replaced.

Specifically, according to the embodiment shown in fig. 1 and 2, the mixer 7 is installed at the middle bottom of the mixing chamber 6, and the fixing groove 8 can fix the test tube containing the nucleic acid detection sample in the mixer 7, thereby ensuring the mixing effect of the device on the detection sample and the detection solvent.

Specifically, according to fig. 1 and 2, in the present embodiment, the first sealing cover 5 and the second sealing cover 9 are both installed on the top surface of the device main body 1, and the first sealing cover 5 and the second sealing cover 9 can respectively seal the inside of the water bath 2 and the inside of the mixing chamber 6, so as to ensure the sealing performance inside the device.

Specifically, according to fig. 1 and fig. 3, in this embodiment, the water bath 2, the mixer 7 and the control panel 10 are electrically connected to the device motor 12, and the power interface 13 can be connected to an external power source and supply power to the device motor 12, so as to ensure the normal operation of the device.

Specifically, according to fig. 1 and 4, in this embodiment, the base 14 is installed at four corners of the bottom of the motor 12 of the device, and the base 14 is made of a rubber shock-absorbing material, so as to ensure the stability of the device.

The working principle and the using process of the utility model are as follows: the pretreatment equipment for nucleic acid detection comprises an external power supply connected with a motor 12 through a power interface 13, an external water pipe connected with a water bath 2 through a connecting port 11 and communicated with the water bath 2, a certain amount of water injected into the water bath 2, a control panel 10 for controlling a constant temperature heating system at the bottom of the water bath 2 to heat water inside the water bath, a sample sealed in a test tube, a water bath 2 fixed on a test tube rack 3, a first sealing cover 5 for inactivation, a test tube taken out and a detection solvent dropped into the test tube after inactivation, and a mixer 7 for mixing, wherein the next procedure of nucleic acid detection can be directly carried out after mixing is finished, the pretreatment equipment is very convenient, improves the efficiency of nucleic acid detection, and reduces the possibility that the sample affects the nucleic acid detection result due to external pollution, the accuracy of nucleic acid detection is ensured.

Finally, it should be noted that: although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that changes may be made in the embodiments and/or equivalents thereof without departing from the spirit and scope of the utility model. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims

1. A pretreatment device for nucleic acid detection, comprising a device main body (1), characterized in that: a water bath kettle (2) is arranged on the left side of the device main body (1), a test tube rack (3) is arranged in the middle of the water bath kettle (2), a communicating port (4) is arranged on the left side inside the water bath pot (2), a first sealing cover (5) is arranged on the top of the water bath pot (2), a mixing cabin (6) is arranged on the right side of the device main body (1), a mixer (7) is arranged in the mixing cabin (6), a fixed groove (8) is arranged in the middle of the mixer (7), a second sealing cover (9) is arranged at the top of the mixing cabin (6), a control panel (10) is arranged below the mixing cabin (6), a connecting port (11) is also arranged at the left side of the device main body (1), the device is characterized in that a device motor (12) is arranged at the bottom end of the device main body (1), a power supply interface (13) is arranged at the back of the device motor (12), and a base (14) is arranged at the bottom of the power supply interface (13).

2. The pretreatment device for nucleic acid detection according to claim 1, wherein: the water bath (2) is arranged inside the device main body (1), and a constant-temperature heating system is arranged at the bottom of the water bath (2).

3. The pretreatment device for nucleic acid detection according to claim 1, wherein: the connection port (4) is arranged on the inner wall of the left side of the water bath pot (2), the connection port (11) can be connected with an external water pipe, and the connection port (11) can pass through the connection port (4) and the inner part of the water bath pot (2) are communicated with each other.

4. The pretreatment device for nucleic acid detection according to claim 1, wherein: the mixer (7) is arranged at the middle bottom of the mixing cabin (6), and the fixing groove (8) can fix the test tube filled with the nucleic acid detection sample in the mixer (7).

5. The pretreatment device for nucleic acid detection according to claim 1, wherein: the first sealing cover (5) and the second sealing cover (9) are arranged on the top surface of the device main body (1), and the first sealing cover (5) and the second sealing cover (9) can respectively seal the insides of the water bath (2) and the mixing cabin (6).

6. The pretreatment device for nucleic acid detection according to claim 1, wherein: the water bath kettle (2), the mixer (7) and the control panel (10) are electrically connected with the device motor (12), and the power interface (13) can be connected with an external power supply and supplies power to the device motor (12).

7. The pretreatment device for nucleic acid detection according to claim 1, wherein: the base (14) is installed at four corners of the bottom of the motor (12), and the base (14) is made of rubber shock-absorbing materials.