CN216434130U - Blood gas-immunity combined detection device - Google Patents
Blood gas-immunity combined detection device Download PDFInfo
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- CN216434130U CN216434130U CN202122113622.3U CN202122113622U CN216434130U CN 216434130 U CN216434130 U CN 216434130U CN 202122113622 U CN202122113622 U CN 202122113622U CN 216434130 U CN216434130 U CN 216434130U
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Abstract
The utility model discloses a blood gas-immunity combined detection device, which comprises: the blood gas sensor is used for testing serum and whole blood, the blood gas sensor is connected with a sample flow path and a photoelectric sensor used for detecting an immune signal, and the photoelectric sensor is connected with an immunity test card through a signal. The blood gas-immunity joint detection device that this embodiment provided has blood gas detection function and immunodetection function concurrently, and two kinds of detections can be accomplished on an instrument, need not a plurality of instruments for detection device integrated level is higher, and it is more convenient to detect, can detect blood gas data and immune data through same sample, has simplified the sampling process.
Description
Technical Field
The utility model belongs to the technical field of biological detection, and particularly relates to a blood gas-immune combined detection device.
Background
Currently, the most commonly used method in medical diagnosis technology, in vitro diagnosis, refers to the analysis of chemical components or chemical reactions by collecting body fluids, excretions, and secretions from human body. Blood gas analysis and fluorescence immunoassay are two common in vitro diagnostic methods, and in the methods, the blood gas analysis is performed by measuring H of blood by using a blood gas analyzer+Concentration and dissolved gases in blood (mainly CO)2、O2) Partial pressure is used for knowing the respiratory function and the acid-base equilibrium state of a human body, and the analysis method can directly reflect the pulmonary ventilation function and the acid-base equilibrium state thereof; fluorescence immunoassay is a detection method combining the specificity of immunological reaction with the sensitivity of fluorescence technology, and can measure low-content bioactive substances by detecting fluorescence generated by excitation on a test card.
However, in the field of in vitro diagnosis at present, different samples need to be measured in different instruments respectively, the types of samples which can be detected by a single testing instrument are few, a plurality of instruments are often required to be used jointly in the clinical diagnosis process, particularly in the diagnosis of emergency treatment and intensive care unit, different instruments need to be operated respectively in the detection process, the operation is complex, the detection is carried out on different instruments, detection reports need to be obtained respectively and further processed so as to correlate the detection results, and in addition, the installation and placement of a plurality of detection devices occupy a large space.
SUMMERY OF THE UTILITY MODEL
Therefore, the present invention is directed to solve the above technical problems, and to provide a blood gas-immune combined detection device capable of simultaneously performing blood gas analysis and fluorescence immunoassay using the same sample.
In order to solve the technical problems, the technical scheme of the utility model is as follows:
the utility model provides a blood gas-immunity combined detection device, which comprises: a blood gas sensor for testing serum and whole blood, blood gas sensor is connected with flow path system and is used for detecting the photoelectric sensor of immunity signal, photoelectric sensor signal connection has the immunity test card.
Preferably, the blood gas sensor is arranged in the sample box, and the flow path system is used for conveying the sample to be measured to the blood gas sensor in the sample box.
Preferably, the surface of the immunoassay test card is printed with an identification code storing sample parameter information, and the detection device further comprises an identification mechanism for reading the identification code.
Preferably, the flow path system comprises a sample line to which at least one peristaltic pump and at least one level sensor are connected.
Preferably, the sample pipeline is further connected with at least one electromagnetic valve, and the sample pipeline is connected with a reagent input pipeline and a waste liquid discharge pipeline through the electromagnetic valve.
Preferably, the sample pipeline is further connected with an air input pipeline.
Preferably, the liquid level sensor is 3, is first liquid level sensor, second liquid level sensor and third liquid level sensor respectively, wherein, first liquid level sensor, second liquid level sensor set up in the sample box, third liquid level sensor connects in the outside sample pipeline of sample box, first liquid level sensor has the sampling needle through sample pipe connection.
Preferably, the blood gas sensor and the photoelectric sensor are arranged in a case, the case is provided with a blood gas sample injection port and an immunity test card injection port, and the blood gas sample injection port is communicated with the sample flow path.
Preferably, a storage unit is arranged in the case, the storage unit is connected with the photoelectric sensor, and the storage unit is used for storing test parameters of the immunity test.
Preferably, the reagent input pipeline and the waste liquid discharge pipeline are arranged in a reagent bag, and one side of the reagent bag is provided with a quality control bag.
Compared with the prior art, the technical scheme of the utility model has the following advantages:
(1) the utility model provides a blood gas-immunity combined detection device, which comprises: the blood gas sensor is used for testing serum and whole blood, the blood gas sensor is connected with a sample flow path and a photoelectric sensor used for detecting an immune signal, and the photoelectric sensor is connected with an immunity test card through a signal. The blood gas-immunity joint detection device that this embodiment provided has blood gas detection function and immunodetection function concurrently, and two kinds of detections can be accomplished on an instrument, need not a plurality of instruments for detection device integrated level is higher, and it is more convenient to detect, can detect blood gas data and immune data through same sample, has simplified the sampling process.
(2) The blood gas immunity combined detection device provided by the utility model has the advantages of good sample flow path tightness, easiness in cleaning and small required sample amount.
Drawings
In order that the present disclosure may be more readily and clearly understood, reference is now made to the following detailed description of the embodiments of the present disclosure taken in conjunction with the accompanying drawings, in which
FIG. 1 is a block diagram of the main components of a combined blood gas-immune detection device provided in an embodiment of the present invention;
FIG. 2 is a schematic diagram of an external structure of a blood gas-immune combined detection device provided in an embodiment of the present invention;
FIG. 3 is a schematic diagram of a flow path system in the integrated blood gas-immune detection device according to an embodiment of the present invention.
The reference numbers in the figures denote: 1-blood gas sensor; 2-a photosensor; 3-a flow path system; 301-sample line; 302-a sampling needle; 303-an electromagnetic valve; 304-a peristaltic pump; 305-a first level sensor; 306-a second liquid level sensor; 307-a third level sensor; 308-air input line; 309-reagent input pipeline; 310-waste liquid discharge line; 311-kit of reagents; 312-quality control package; 313-a quality control product pipeline; 4-sample box; 5-a case; 501-a sample inlet of a blood gas sample; 502-immunoassay card inlet.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are some, but not all, embodiments of the present invention. The components of embodiments of the present invention generally described and illustrated in the figures herein may be arranged and designed in a wide variety of different configurations.
Thus, the following detailed description of the embodiments of the present invention, presented in the figures, is not intended to limit the scope of the utility model, as claimed, but is merely representative of selected embodiments of the utility model. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
In the description of the present invention, it is to be understood that the terms "upper", "lower", and the like, indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, or orientations or positional relationships that are conventionally placed when products of the present invention are used, or orientations or positional relationships that are conventionally understood by those skilled in the art, and are used only for convenience in describing the present invention and simplifying the description, but do not indicate or imply that the equipment or elements that are referred to must have a specific orientation, be constructed in a specific orientation, and be operated, and thus, should not be construed as limiting the present invention.
The terms "first", "second", etc. in the description of the present invention are used for distinguishing between them and not for distinguishing between them.
In the description of the present invention, it should also be noted that, unless otherwise explicitly specified or limited, the terms "disposed" and "mounted" are to be construed broadly, e.g., as being fixedly attached, detachably attached, or integrally attached; may be directly connected or indirectly connected through an intermediate. The specific meanings of the above terms in the present invention can be understood in specific cases to those skilled in the art. It should be understood that the above examples are only for clarity of illustration and are not intended to limit the embodiments. Other variations and modifications will be apparent to persons skilled in the art in light of the above description. And are neither required nor exhaustive of all embodiments. And obvious variations or modifications therefrom are within the scope of the utility model.
Examples
The embodiment provides a blood gas-immune combined detection device, please refer to fig. 1, the detection device comprises a blood gas sensor 1 for testing serum and whole blood, the blood gas sensor 1 is connected with a photoelectric sensor 2 for detecting immune signals of a sample through signals, the blood gas sensor 1 is further connected with a flow path system 3 for conveying a sample to be tested and a reagent, the photoelectric sensor 2 is connected with an immune test card through signals, and the immune test card is added with the sample to be tested.
The blood gas-immunity joint detection device provided by the embodiment has the blood gas detection function and the immunity detection function, two kinds of detection can be completed on one instrument without a plurality of instruments, so that the detection device has higher integration level and is more convenient and quick to detect, and the blood gas data and the immunity data can be detected through the same sample, thereby simplifying the sampling process.
Specifically, in the detection apparatus provided in this embodiment, the blood gas sensor 1 is a sensor capable of simultaneously testing serum and whole blood, and when testing whole blood, all preset parameters are valid, and when testing serum, some preset parameters are valid.
The blood gas sensor 1 is arranged in a sample box 4, and the flow path system 3 is used for conveying a sample to be tested and a reagent into the sample box 4 and conveying the sample to the blood gas sensor 1 for blood gas test.
Referring to fig. 2, a case 5 is further disposed outside the sample box 4, and the photoelectric sensor 2 is also disposed inside the case 5, so that the blood gas detection device and the immunity detection device are integrated into one instrument, and the blood gas detection and the immunity detection do not need to be performed on two instruments respectively.
The case 5 is provided with a blood and gas sample inlet 501 for inputting a blood sample and an immunity test card inlet 502 for inserting an immunity test card, wherein the immunity test card inlet 502 is used for accommodating the immunity test card, and the photoelectric sensor 2 is arranged in the case 5 at a position corresponding to the immunity test card and used for detecting a fluorescent signal of the immunity test card to perform immunity detection. The immunoassay test card is a test card adopting fluorescence immunochromatography technology, when a sample to be tested is heated into a reagent card, substances to be tested in the sample are chromatographed on a Nitrocellulose (NC) membrane to generate a binding reaction with fluorescent substances, and then a fluorescent signal is generated.
In order to combine the blood gas and the immune detection result, an identification code storing sample parameter information is printed on the surface of the immune test card, the identification code is a two-dimensional code obtained by compressing batch parameters of the immune test card, the batch number of the immune test card can be obtained by identifying the two-dimensional code, and in order to read the two-dimensional code, an identification mechanism (not shown in the figure) for reading the two-dimensional code is arranged in the case 5, wherein in the embodiment, the identification mechanism is a two-dimensional code identification scanner. During detection, the identification mechanism identifies the two-dimensional code information, decodes the two-dimensional code information, transmits the decoded information to the storage unit (a host of the blood gas analyzer), the storage unit issues detection parameters according to the batch number of the test card, the photoelectric sensor 2 performs immunodetection, and the control unit is connected to the blood gas sensor 1 at the same time.
Further, in order to ensure the strength of the test signal, the photoelectric sensor 2 is connected with a signal conversion circuit, which is used for converting an optical signal into an electrical signal and amplifying the converted signal, and further comprises an analysis circuit, which is used for converting the photoelectric signal into a digital signal and analyzing the digital signal to obtain an immunodetection result. The conversion circuit and the analysis circuit are conventional circuit structures, and can realize conversion among photoelectric signals, photoelectric signals and digital signals.
As shown in fig. 3, the flow path system 3 includes a sample pipeline 301, one end of the sample pipeline 301 is connected to a sampling needle 302, the sampling needle 302 is connected to a blood gas sample injection port 501, a blood sample to be detected is conveyed to a sample box, the other end of the sample pipeline is connected to a blood sample input end, the sample pipeline 301 is provided with a plurality of electromagnetic valves 303, please refer to the drawing, in this embodiment, 12 electromagnetic valves are respectively electromagnetic valves F1 and F2 … … F12, for convenience of sample injection, the sample pipeline 301 is further connected to 3 peristaltic pumps 304 respectively peristaltic pumps M1-M3, one end of the peristaltic pump M1 is connected to the sampling needle 302 through a pipeline, and the other end of the peristaltic pump M1 is connected to a waste liquid outlet; the sample pipeline 301 is further connected with 3 liquid level sensors, which are a first liquid level sensor 305, a second liquid level sensor 306 and a third liquid level sensor 307, wherein one end of the first liquid level sensor 301 is connected to the sample pipeline 301 and communicated with the sampling needle 302, the other end of the first liquid level sensor 301 is connected to a peristaltic pump M2, the other end of the peristaltic pump M2 is sequentially connected with electromagnetic valves F12, F1, F11 and F3 to the sample pipeline 301, and the electromagnetic valves F3, F4, F5, F6 and F7 are sequentially arranged towards the direction of the sampling needle 302 on the sample pipeline 301.
The sample pipeline 301 is further communicated with an air input pipeline 308, the air input pipeline 308 is used for conveying air into the sample pipeline 301, one end of the air input pipeline 308 is provided with an air inlet, electromagnetic valves F2, F8, F9 and F10 are sequentially arranged along the direction far away from the air inlet, and the electromagnetic valve F10 is connected with the electromagnetic valve F3 through a pipeline.
The electromagnetic valves F7, F6, F5, F4 and F3 are connected to the liquid inlets of the reagent 1, the reagent 2, the reagent 3, the reagent 4 and the reagent 5, respectively, and the reagents 1 to 5 are conventional reagents having a calibration function and a cleanable flow path system. The reagents 1 to 5 are connected to the corresponding solenoid valves through the respective reagent input pipes 309, and further connected to the sample pipe 301, and the waste liquid outlet is disposed on the waste liquid discharge pipe 310 for discharging the waste liquid in the flow path system. In order to ensure that the flow path system is integrally tidy and each pipeline is regularly installed, the reagent input pipeline 309 and the waste liquid discharge pipeline 310 are integrally arranged in a reagent bag 311, one side of the reagent bag 311 is provided with a quality control bag 312, three quality control product pipelines 313 are arranged in the quality control bag 312 and used for inputting 3 blood and gas quality control products with different concentration levels into the flow path system, and the three quality control product pipelines 313 are respectively connected with electromagnetic valves F10, F9 and F8.
The working process of the flow path system 3 in this embodiment includes:
calibration: the peristaltic pump M2 conveys the calibration liquid to the first liquid level sensor 305 to stop, then the peristaltic pump M3 conveys the calibration liquid to the third liquid level sensor 307, and after the calibration is finished, the peristaltic pump M3 conveys the waste liquid to the waste liquid discharge pipeline 308;
cleaning a sample pipeline: the peristaltic pump M3 inputs the cleaning solution into the sample pipeline 301, and the sample pipeline is cleaned and then discharged to the waste liquid discharge pipeline 308;
sample input: the sampling needle 302 is inserted into a blood sample for sample suction, the peristaltic pump M3 is used for conveying the sample to the second liquid level sensor 306, the second liquid level sensor 306 prompts stopping sample suction after detecting that the sample is in place, then the sample is continuously conveyed to the third liquid level sensor 307 and is detected by the blood gas sensor 1, and after the detection is finished, the cleaning operation is executed again.
When the blood gas sensor 1 detects a sample, in order to improve the detection precision, the blood gas sensor 1 is further connected with an amplifying circuit to amplify the signal of the sensor to obtain an analog signal, the analog signal is converted into a digital signal through an AD conversion circuit, and the digital signal is transmitted to a control circuit to control mechanisms such as various electromagnetic valves and peristaltic pumps on a pipeline.
It should be understood that the above examples are only for clarity of illustration and are not intended to limit the embodiments. Other variations and modifications will be apparent to persons skilled in the art in light of the above description. And are neither required nor exhaustive of all embodiments. And obvious variations or modifications therefrom are within the scope of the utility model.
Claims (10)
1. A blood gas-immune combined detection device, comprising: a blood gas sensor for testing serum and whole blood, blood gas sensor is connected with flow path system and is used for detecting the photoelectric sensor of immunity signal, photoelectric sensor signal connection has the immunity test card.
2. The integrated blood gas-immune detector according to claim 1, further comprising a sample box, wherein the blood gas sensor is disposed in the sample box, and the flow path system is used for conveying the sample to be detected to the blood gas sensor in the sample box.
3. The integrated blood gas-immune detector as set forth in claim 2, wherein the immune test card has an identification code on its surface for storing sample parameter information, and the detector further comprises an identification mechanism for reading the identification code.
4. The integrated blood gas-immune detector according to claim 2 or 3, wherein the flow path system comprises a sample line, and at least one peristaltic pump and at least one liquid level sensor are connected to the sample line.
5. The integrated blood gas-immune detector according to claim 4, wherein the sample tube is further connected with at least one electromagnetic valve, and the sample tube is connected with a reagent input tube and a waste liquid discharge tube through the electromagnetic valve.
6. The integrated blood gas-immune detector as set forth in claim 5, wherein the sample line is further connected with an air input line.
7. The integrated blood gas-immune detection device according to claim 6, wherein the number of the liquid level sensors is 3, and the liquid level sensors are respectively a first liquid level sensor, a second liquid level sensor and a third liquid level sensor, wherein the first liquid level sensor and the second liquid level sensor are arranged in the sample box, the third liquid level sensor is connected to a sample pipeline outside the sample box, and the first liquid level sensor is connected with a sampling needle through the sample pipeline.
8. The integrated blood gas-immune detector according to claim 7, wherein the blood gas sensor and the photoelectric sensor are disposed inside a case, the case is provided with a blood gas sample inlet and an immune test card inlet, and the blood gas sample inlet is communicated with the sample pipeline.
9. The integrated blood gas-immune detection device according to claim 8, wherein a storage unit is arranged in the case, the storage unit is connected with the photoelectric sensor, and the storage unit is used for storing test parameters of an immune test.
10. The integrated blood gas-immune detector according to claim 5, wherein the reagent input pipeline and the waste liquid discharge pipeline are disposed in a reagent bag, and a quality control bag is disposed on one side of the reagent bag.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN202122113622.3U CN216434130U (en) | 2021-09-02 | 2021-09-02 | Blood gas-immunity combined detection device |
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| Application Number | Priority Date | Filing Date | Title |
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| CN202122113622.3U CN216434130U (en) | 2021-09-02 | 2021-09-02 | Blood gas-immunity combined detection device |
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| CN216434130U true CN216434130U (en) | 2022-05-03 |
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