CN216433689U - Dyeing module of full-automatic pathological staining instrument - Google Patents

Dyeing module of full-automatic pathological staining instrument Download PDF

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Publication number
CN216433689U
CN216433689U CN202122927571.8U CN202122927571U CN216433689U CN 216433689 U CN216433689 U CN 216433689U CN 202122927571 U CN202122927571 U CN 202122927571U CN 216433689 U CN216433689 U CN 216433689U
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China
Prior art keywords
module
box body
staining
base
cover
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Active
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CN202122927571.8U
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Chinese (zh)
Inventor
陈赞烽
熊玉林
林齐心
阮宝淇
蒋祺樑
王伟槟
林大青
黄汉清
林婉蓉
李妙君
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Lumingte Biological System Co ltd
Fuzhou Maixin Biotech Co ltd
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Lumingte Biological System Co ltd
Fuzhou Maixin Biotech Co ltd
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Abstract

The utility model discloses a dyeing module of full-automatic pathological staining instrument, include: the module comprises a module base, the module box body is arranged above the module base, an opening is formed above the module box body, a module cover is arranged above the module box body, the module base is in threaded connection with the module box body, the bottom of the module box body is provided with a heating sheet, a transmission rod is arranged on the module base, the transmission rod is connected with the module cover, one side of the module base is provided with a driving assembly and a cover closing sensor, the bottom of the module base is provided with a magnetic valve, the lower portion of the module cover is provided with a cover opening sensor and a cover opening limiter, a plurality of module grooves are formed in the module box body, each module groove is respectively provided with a heat conducting block, and a wind shield is arranged between two adjacent module grooves. The utility model discloses a dyeing module of full-automatic pathological staining appearance combines through transfer line, closing lid sensor, magnetic force valve, the sensor of uncapping and the stopper of uncapping, provides dual fail-safe, and the switch lid angle of control module lid more accurately, the security is higher, and the durability is stronger.

Description

Dyeing module of full-automatic pathological staining instrument
Technical Field
The utility model relates to an immunohistochemistry and immunocytochemistry dyeing technical field especially relate to a dyeing module of full-automatic pathological staining appearance.
Background
The current module lid switch passes through the belt and connects, and the belt often breaks or warp, influences module switch lid, leads to arm secondary damage, and the fault rate is on the high side, seriously influences the dyeing result, and the cost is great.
Therefore, a dyeing module of a fully automatic pathological staining apparatus is needed.
SUMMERY OF THE UTILITY MODEL
The utility model aims at providing a dyeing module of full-automatic pathological staining appearance to solve the problem among the above-mentioned prior art, the switch that can control the module lid accurately covers the angle, and the security is higher, and the durability is stronger.
The utility model provides a dyeing module of full-automatic pathological staining instrument, wherein, include:
a module base, a module box body is arranged above the module base, an opening is arranged above the module box body, a module cover hinged with the module box body is arranged at an opening above the module box body, the module base is in threaded connection with the module box body, the bottom of the module box body is provided with a heating plate, the module base is provided with a transmission rod, the transmission rod is connected with the module cover, a driving component and a cover closing sensor are arranged on one side of the module base, a magnetic valve is arranged at the bottom of the module base, an uncovering sensor and an uncovering limiter are arranged below the module cover, a plurality of module grooves for storing reagents are transversely and continuously arranged in the module box body, one end of each module groove is opened and communicated, and each module groove is internally provided with a heat conduction block, and a wind shield is arranged between two adjacent module grooves.
The dyeing module of the fully automatic pathological staining instrument as described above, wherein preferably, the dyeing module of the fully automatic pathological staining instrument further includes a drainage hole disposed on the module base and capable of extending to the outer side of the bottom of the module base, and the drainage hole is connected with the module box body in an inserting manner.
The dyeing module of the fully automatic pathological staining apparatus as described above, wherein preferably, the dyeing module of the fully automatic pathological staining apparatus further comprises an air flow fence disposed around the module box.
The dyeing module of the fully automatic pathological staining instrument preferably further comprises a sealing ring arranged at the opening of the module box body and matched with the inner peripheral side of the module cover.
The dyeing module of the fully automatic pathological staining instrument is characterized by further comprising an overflow hole arranged in the module box body.
The dyeing module of the full-automatic pathological staining instrument preferably further comprises a glass slide clamp arranged in the module box body and separated from the module box body.
The dyeing module of the full-automatic pathological staining instrument is characterized in that a plurality of first threaded holes are formed in the outer side of the lower edge of the module box body, a plurality of second threaded holes matched with the first threaded holes are formed in the module base, and the module base is connected with the module box body through connecting screws penetrating through the plurality of first threaded holes and the plurality of second threaded holes.
The dyeing module of the fully automatic pathological staining instrument is characterized in that the number of the first threaded holes is 4, the first threaded holes are symmetrically arranged at the outer sides of the lower edges of the two long edges of the module box body, and the number of the second threaded holes is 4, and the second threaded holes are respectively arranged on the two long edges of the module base.
The dyeing module of the fully automatic pathological staining apparatus as described above, wherein it is preferable that the dyeing module of the fully automatic pathological staining apparatus further includes two fans provided on the module base.
The dyeing module of the fully automatic pathological staining apparatus as described above, wherein preferably, the dyeing module of the fully automatic pathological staining apparatus further comprises a horizontal adjusting knob disposed on the module base.
The utility model provides a dyeing module of a full-automatic pathological staining instrument, which combines a transmission rod, a cover closing sensor, a magnetic valve, a cover opening sensor and a cover opening limiter to provide double insurance, more accurately control the cover opening and closing angle of a module cover, and has higher safety and stronger durability; the split design is adopted, so that the disassembly and the maintenance are convenient, and the replacement cost is reduced; the heat conduction block is directly contacted with the glass slide, the glass slide is not completely attached to the heating sheet, the direct contact of the glass slide and the heating sheet during high-temperature antigen restoration is avoided, a heat conduction medium is changed, and therefore the cell morphology is improved; through the two fans and the airflow fence, the airflow can cool the bottom and the periphery of the module simultaneously, so that the cooling efficiency is improved; through the overflow hole, other faults caused by liquid overflow are avoided; the internal structure of the staining module is simplified, the volume of the module is reduced, the heating efficiency and the cooling efficiency of the module are improved, the staining time is shortened, and the cell morphology in the tissue section is improved.
Drawings
In order to make the objects, technical solutions and advantages of the present invention clearer, the present invention will be further described with reference to the accompanying drawings, in which:
fig. 1 is a merged structural diagram of an embodiment of a dyeing module of the fully automatic pathological staining apparatus provided by the present invention;
fig. 2 is a separated structure diagram of the dyeing module of the fully automatic pathological staining apparatus provided by the utility model;
fig. 3 is a side view of the dyeing module of the fully automatic pathological staining apparatus provided by the present invention.
Description of reference numerals:
1-module case 2-module cover 3-airflow fence
4-module base 5-horizontal adjusting knob 6-cover opening limiter
7-cover opening sensor 8-connecting screw rod 9-transmission rod
10-fan 11-drain hole 12-magnetic valve
13-overflow hole 14-wind shield 15-heat conducting block
16-sealing ring 17-glass sheet clamp 18-heating sheet
19-drive assembly 20-close cover sensor 21-module slot
Detailed Description
Various exemplary embodiments of the present disclosure will now be described in detail with reference to the accompanying drawings. The description of the exemplary embodiments is merely illustrative and is in no way intended to limit the disclosure, its application, or uses. The present disclosure may be embodied in many different forms and is not limited to the embodiments described herein. These embodiments are provided so that this disclosure will be thorough and complete, and will fully convey the scope of the disclosure to those skilled in the art. It should be noted that: the relative arrangement of parts and steps, the composition of materials, numerical expressions and numerical values set forth in these embodiments are to be construed as merely illustrative, and not as limitative, unless specifically stated otherwise.
As used in this disclosure, "first", "second": and the like, do not denote any order, quantity, or importance, but rather are used to distinguish one element from another. The word "comprising" or "comprises", and the like, means that the element preceding the word covers the element listed after the word, and does not exclude the possibility that other elements are also covered. "upper", "lower", and the like are used merely to indicate relative positional relationships, and when the absolute position of the object being described is changed, the relative positional relationships may also be changed accordingly.
In the present disclosure, when a specific component is described as being located between a first component and a second component, there may or may not be intervening components between the specific component and the first component or the second component. When it is described that a specific component is connected to other components, the specific component may be directly connected to the other components without having an intervening component, or may be directly connected to the other components without having an intervening component.
All terms (including technical or scientific terms) used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this disclosure belongs unless specifically defined otherwise. It will be further understood that terms, such as those defined in commonly used dictionaries, should be interpreted as having a meaning that is consistent with their meaning in the context of the relevant art and will not be interpreted in an idealized or overly formal sense unless expressly so defined herein.
Techniques, methods, and apparatus known to those of ordinary skill in the relevant art may not be discussed in detail, but are intended to be part of the specification where appropriate.
As shown in fig. 1-3, the embodiment of the utility model provides a dyeing module of full-automatic pathological staining instrument, it includes: a module base 4, a module box body 1 is arranged above the module base 4, an opening is arranged above the module box body 1, a module cover 2 hinged with the module box body 1 is arranged at the opening above the module box body 1, the module base 4 is in threaded connection with the module box body 1, a heating plate 18 is arranged at the bottom of the module box body 1, a transmission rod 9 is arranged on the module base 4, the transmission rod 9 is connected with the module cover 2, a driving component 19 and a cover closing sensor 20 are arranged at one side of the module base 4, a magnetic valve 12 is arranged at the bottom of the module base 4, an cover opening sensor 7 and a cover opening limiter 6 are arranged below the module cover 2, a plurality of module grooves 21 for storing reagents are transversely and continuously arranged in the module box body 1, one end of each module groove 21 is opened and communicated, and a heat conduction block 15 is respectively arranged in each module groove 21, a wind deflector 14 is disposed between two adjacent module grooves 21.
Wherein, in the utility model discloses in, drive assembly 19 is the motor, heat conduction piece 15 is the metal heat conduction piece, is the stainless steel heat conduction piece for example.
Furthermore, a plurality of first threaded holes are formed in the outer side of the lower edge of the module box body 1, a plurality of second threaded holes matched with the first threaded holes are formed in the module base 4, and the module base 4 is connected with the module box body 1 through connecting screws penetrating through the plurality of first threaded holes and the plurality of second threaded holes. Particularly, in the utility model discloses in, the quantity of first screw hole is 4, sets up symmetrically the lower edge outside on two long limits of module box body 1, the quantity of second screw hole is 4, sets up respectively on two long edges of module base 4. It should be noted that the present invention does not specifically limit the number and distribution positions of the first threaded holes and the second threaded holes.
In the work, the transmission rod 9 is adopted to replace a belt, when the module cover 2 is opened, the cover closing sensor 20 senses a signal that the module cover 2 is in an open state and then controls the driving assembly 19 to stop rotating, and the cover closing sensor is combined with the cover opening limiter 6 for use, so that a double-safety effect is achieved, the cover opening and closing angle of the module cover 2 is prevented from deviating, and the control is more accurate; the utility model discloses a dyeing module adopts split type design, and dyeing module wholly divide into the module box body 1 of upper portion and the module base 4 of lower part, and the upper and lower two parts of dyeing module pass through threaded connection, and convenient to detach and maintenance have reduced the replacement cost; because the existence of the heat conduction block 15, the slide and the heating sheet 18 are not completely attached, and a gap of 2-5mm is arranged between the slide and the heating sheet, the slide is prevented from being directly contacted with the heating sheet 18 during high-temperature antigen restoration, but the heat conduction block 15 is directly contacted with the slide to change a heat conduction medium, so that the cell morphology is improved.
Therefore, compared with the prior art, double insurance is provided by combining the transmission rod, the cover closing sensor, the magnetic valve, the cover opening sensor and the cover opening limiter, the cover opening and closing angle of the module cover is controlled more accurately, the safety is higher, and the durability is stronger; the split type design is adopted, so that the disassembly and the maintenance are convenient, and the replacement cost is reduced; the heat conduction block is directly contacted with the glass slide, the glass slide is not completely attached to the heating sheet, the direct contact of the glass slide and the heating sheet is avoided when the high-temperature antigen is repaired, the heat conduction medium is changed, and therefore the cell morphology is improved.
Further, the dyeing module of the full-automatic pathological staining apparatus further comprises a drain hole 11 which is arranged on the module base 4 and can extend to the outer side of the bottom of the module base 4, and the drain hole 11 is connected with the module box body 1 in a butt-inserting manner. In the present invention, the number of the drain holes 11 is 1.
Further, the dyeing module of the full-automatic pathological staining instrument further comprises an airflow fence 3 arranged around the module box body 1. The current module cooling only depends on a fan to cool, and the air current only can blow to the bottom of the dyeing module, so that the cooling area is small. The utility model discloses an air current rail 3 can change the cooling duct, and greatly increased dyeing module's cooling area for the cooling rate of dyeing module main part has improved cooling efficiency.
Further, the dyeing module of full-automatic pathological staining appearance is still including setting up the opening part of module box body 1, and have with the interior periphery side complex sealing washer 16 of module lid 2. Furthermore, the dyeing module of the fully automatic pathological staining instrument further comprises an overflow hole 13 arranged in the module box body 1. When the module cover 2 is closed, the module cover 2 is tightly covered and tightly attached to the sealing ring 16, the overflow hole 13 is blocked, the dyeing module is completely in a sealing state, and liquid cannot overflow due to excessive liquid; when the module cover 2 is opened, the overflow hole 13 cannot be pressed by the module cover 2 and the sealing ring 16, when the instrument fails to cause excessive liquid in the dyeing module, the liquid can flow out of the overflow hole 13, and other failures caused by liquid overflow are avoided. Current dyeing module does not have the overflow design, and when some trouble appears in the instrument, the instrument can continue to go into liquid to dyeing module in, leads to liquid too many, overflows outside dyeing module, damages other devices of dyeing module below, easily causes the short circuit, has the potential safety hazard, the utility model discloses an increase overflow hole 13, can avoid liquid excessive to cause other troubles.
Furthermore, the dyeing module of the full-automatic pathological staining apparatus further comprises a glass clip 17 which is arranged in the module box body 1 and is separated from the module box body 1. When dyeing is needed, the slide is clamped in the slide clamp 17 and then placed in the module box body 1.
Further, the dyeing module of the fully automatic pathological staining apparatus further comprises two fans 10 disposed on the module base 4, and the number of the fans 10 is two. The fan number of present dyeing module is 1, the utility model discloses an increase a fan, can further improve cooling efficiency.
Furthermore, the dyeing module of the fully automatic pathological staining instrument further comprises a horizontal adjusting knob 5 arranged on the module base 4, and the levelness of the dyeing module can be adjusted through the horizontal adjusting knob 5.
Compare with present dyeing module, the utility model discloses simplify the inner structure of dyeing module, dwindled the module volume simultaneously. In the immunohistochemical antigen retrieval step, a large amount of antigen retrieval liquid is injected into the staining module, so that the antigen retrieval liquid completely submerges the tissue section on the glass slide clamp, and is heated to 95-100 ℃ for 20min or so. The utility model discloses after reducing the module volume and simplifying module inner structure, the self thermal capacity of module diminishes, has improved module intensification efficiency and cooling efficiency, has not only shortened the dyeing time, has still improved the cell form among the tissue slice.
The embodiment of the utility model provides a dyeing module of full-automatic pathological staining instrument combines through transfer line, close and covers sensor, magnetic valve, the sensor of uncapping and the stopper of uncapping, provides dual fail-safe, and the switch lid angle of control module lid more accurately, the security is higher, and the durability is stronger; the split design is adopted, so that the disassembly and the maintenance are convenient, and the replacement cost is reduced; the heat conduction block is directly contacted with the glass slide, the glass slide is not completely attached to the heating sheet, the direct contact of the glass slide and the heating sheet during high-temperature antigen restoration is avoided, a heat conduction medium is changed, and therefore the cell morphology is improved; through the two fans and the airflow fence, the airflow can cool the bottom and the periphery of the module simultaneously, so that the cooling efficiency is improved; through the overflow hole, other faults caused by liquid overflow are avoided; the internal structure of the staining module is simplified, the volume of the module is reduced, the heating efficiency and the cooling efficiency of the module are improved, the staining time is shortened, and the cell morphology in the tissue section is improved.
Thus, various embodiments of the present disclosure have been described in detail. Some details that are well known in the art have not been described in order to avoid obscuring the concepts of the present disclosure. It will be fully apparent to those skilled in the art from the foregoing description how to practice the presently disclosed embodiments.
Although some specific embodiments of the present disclosure have been described in detail by way of example, it should be understood by those skilled in the art that the foregoing examples are for purposes of illustration only and are not intended to limit the scope of the present disclosure. It will be understood by those skilled in the art that various changes may be made in the above embodiments or equivalents may be substituted for elements thereof without departing from the scope and spirit of the present disclosure. The scope of the present disclosure is defined by the appended claims.

Claims (10)

1. The utility model provides a dyeing module of full-automatic pathological staining appearance which characterized in that includes:
a module base, a module box body is arranged above the module base, an opening is arranged above the module box body, a module cover hinged with the module box body is arranged at an opening above the module box body, the module base is in threaded connection with the module box body, the bottom of the module box body is provided with a heating plate, the module base is provided with a transmission rod, the transmission rod is connected with the module cover, a driving component and a cover closing sensor are arranged on one side of the module base, a magnetic valve is arranged at the bottom of the module base, an uncovering sensor and an uncovering limiter are arranged below the module cover, a plurality of module grooves for storing reagents are transversely and continuously arranged in the module box body, one end of each module groove is opened and communicated, and a heat conduction block is respectively arranged in each module groove, and a wind shield is arranged between two adjacent module grooves.
2. The staining module of the full automatic pathological staining machine according to claim 1, further comprising a drainage hole disposed on the module base and extending to the outside of the bottom of the module base, wherein the drainage hole is connected with the module box body in an inserting manner.
3. The staining module of the fully automatic morbid staining apparatus of claim 1, wherein the staining module of the fully automatic morbid staining apparatus further comprises an air flow fence disposed around the module box.
4. The dyeing module of the fully automatic pathological staining instrument according to claim 1, further comprising a sealing ring disposed at the opening of the module case and engaged with the inner circumference of the module cover.
5. The staining module of the fully automatic pathological staining instrument of claim 4, further comprising an overflow aperture disposed within the module cartridge.
6. The staining module of the full-automatic pathological staining instrument of claim 1, further comprising a slide holder disposed in the module box and separated from the module box.
7. The staining module of the full-automatic pathological staining instrument of claim 1, wherein a plurality of first threaded holes are formed outside the lower edge of the module box body, a plurality of second threaded holes matched with the first threaded holes are formed in the module base, and the module base is connected with the module box body through connecting screws penetrating through the plurality of first threaded holes and the plurality of second threaded holes.
8. The staining module of the full automatic pathological staining instrument of claim 7, wherein the number of the first threaded holes is 4, and the first threaded holes are symmetrically arranged at the outer sides of the lower edges of the two long sides of the module box body, and the number of the second threaded holes is 4, and the second threaded holes are respectively arranged at the two long sides of the module base.
9. The staining module of the fully automatic pathological staining instrument of claim 1, further comprising two fans disposed on the module base.
10. The staining module of the fully automatic pathological staining apparatus of claim 1, further comprising a horizontal adjustment knob disposed on the module base.
CN202122927571.8U 2021-11-24 2021-11-24 Dyeing module of full-automatic pathological staining instrument Active CN216433689U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202122927571.8U CN216433689U (en) 2021-11-24 2021-11-24 Dyeing module of full-automatic pathological staining instrument

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202122927571.8U CN216433689U (en) 2021-11-24 2021-11-24 Dyeing module of full-automatic pathological staining instrument

Publications (1)

Publication Number Publication Date
CN216433689U true CN216433689U (en) 2022-05-03

Family

ID=81341511

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Application Number Title Priority Date Filing Date
CN202122927571.8U Active CN216433689U (en) 2021-11-24 2021-11-24 Dyeing module of full-automatic pathological staining instrument

Country Status (1)

Country Link
CN (1) CN216433689U (en)

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