CN216410836U

CN216410836U - Chromosome dropping device

Info

Publication number: CN216410836U
Application number: CN202220510726.XU
Authority: CN
Inventors: 马宁; 杨晓; 李�昊; 朱丽娜
Original assignee: 7th Medical Center of PLA General Hospital
Current assignee: 7th Medical Center of PLA General Hospital
Priority date: 2022-03-09
Filing date: 2022-03-09
Publication date: 2022-04-29
Anticipated expiration: 2032-03-09

Abstract

The utility model discloses a chromosome dripping device, which comprises a supporting plate, wherein supporting legs are arranged at four corners of the bottom end of the supporting plate, the lower ends of the supporting legs are fixedly connected with a cross bar, a material receiving box is arranged at the middle part of the cross bar, the cross bar is fixedly connected with limiting plates at two sides of the material receiving box, a handle is arranged on the box wall of the material receiving box, two ends of the cross bar are fixedly connected with a longitudinal beam, the upper end of the longitudinal beam is provided with a sliding chute, the upper end of the longitudinal beam is provided with a supporting seat, the bottom end of the supporting seat is symmetrically provided with supporting wheels, the upper end of the supporting seat is fixedly connected with a supporting column, the upper part of the supporting column is provided with a movable rod in sliding connection, the movable rod is provided with a plurality of extruding structures, one end of the movable rod, which is positioned outside the supporting column, is fixedly connected with a pressing block, a spring is sleeved at the position of the movable rod, the supporting column is fixedly connected with the transverse plate at the lower part of the movable rod, the dripping device is designed to improve the stability of a dripping piece, the liquid dropping efficiency is improved by dropping liquid to a plurality of glass slides at one time.

Description

Chromosome dropping device

Technical Field

The utility model relates to the technical field of medical diagnosis equipment, in particular to a chromosome dripping device.

Background

Chromosomes are a specific form of DNA that exists in eukaryotic cells at mitosis or meiosis, and are formed by chromatin strands that spiral around, and gradually shorten and thicken. Only in the metaphase (all chromosomes are arranged in their condensed form in the center of the cell) are chromosomes visible under the light microscope. Before this, each chromosome has been replicated once (S phase), the original chromosome and its copy are called sister chromosomes, and the two chromosomes are connected by a centromere. If the centromere is located in the middle of the chromosome, an X-shaped chromosome structure is generated; if the centromere is located near one of the ends, a two-armed chromosome structure results. The X-shaped structural chromosome is called a metaphase chromosome. In this highly concentrated form, chromosomes are most easily distinguished and studied, are readily colored by basic dyes (e.g., gentian violet and aceto magenta), and are therefore named.

The Chinese patent discloses a chromosome specimen dripping device (No. CN201780226U), and the technology of the patent can solve the problem of poor stability in the existing dripping process, but only can realize dripping once in each operation, so that the efficiency is low, and redundant dye liquor cannot be collected. Accordingly, one skilled in the art provides a chromosome plating apparatus to solve the problems set forth in the background art described above.

SUMMERY OF THE UTILITY MODEL

In order to solve the technical problem, the utility model provides a chromosome dripping device which comprises a supporting plate, supporting legs are installed at four corners of the bottom end of the supporting plate, the lower ends of the supporting legs are fixedly connected with a cross rod, a material receiving box is arranged in the middle of the cross rod, the cross rod is located at two sides of the material receiving box and fixedly connected with limiting plates, a handle is installed on the box wall of the material receiving box, longitudinal beams are fixedly connected with two ends of the cross rod, a sliding groove is formed in the upper end of each longitudinal beam, a supporting seat is arranged at the upper end of each longitudinal beam, supporting wheels are symmetrically installed at the bottom end of each supporting seat, supporting columns are fixedly connected with the upper ends of the supporting seats, a sliding-connected movable rod is installed on the upper portions of the supporting columns, a plurality of extruding structures are installed on the movable rods, a pressing block is fixedly connected with one end of each movable rod located on the outer sides of the supporting columns, springs are sleeved on the movable rods, and the supporting columns are located below the movable rods and fixedly connected with the transverse plates.

Preferably: the material extruding structure comprises a fixing sleeve, the lower end of the fixing sleeve is fixedly connected with a pressing plate, and the pressing plate is arranged in an L shape.

Preferably: a clamping groove for mounting the dropper is formed in one side, located on the pressing plate, of the transverse plate, a protruding block for clamping the dropper is arranged on the inner wall of the clamping groove, the upper portion of the dropper is located on one side of the pressing plate, and a baffle is arranged on the other side, located on the dropper, of the upper end of the transverse plate.

Preferably: the upper end of the supporting plate is provided with a groove, a plurality of supporting strips are arranged in the groove, and the supporting strips are used for supporting the glass slide.

Preferably: a plurality of be equipped with the shelves strip between the support bar, the shelves strip is pressed close to slide glass one end, and the lateral wall fixedly connected with a plurality of dogs that the shelves strip is close to the support bar, and the dog is used for the slide location.

Preferably: and a plurality of blanking holes for leaking reagents are formed in the middle of the supporting plate.

The utility model has the technical effects and advantages that:

1. in the utility model, one end of the glass slide is placed on the side wall of the blocking strip, the edge of the glass slide is close to the stop block, the other end of the glass slide is placed at the upper end of the supporting strip, and the glass slide is inclined, so that the glass slide can be completely soaked with the dye solution when dyeing is carried out, and the dye solution is saved compared with the existing incubation box.

2. According to the utility model, dye liquid flowing out of the glass slide flows into the groove of the supporting plate, passes through the blanking hole, falls into the material receiving box for collection, pulls the material receiving box, takes out the material receiving box, and is convenient for cleaning the material receiving box.

3. The design of this piece device of dripping improves the stability of piece of dripping, once to a plurality of slide glass dropping liquids, improves the efficiency of dropping liquid.

Drawings

FIG. 1 is a schematic structural diagram of a chromosome slide dropping device provided in an embodiment of the present application;

FIG. 2 is a bottom view of a chromosome plating apparatus provided in an embodiment of the present application;

FIG. 3 is an enlarged schematic view of the structure at A in FIG. 1 in the chromosome plating apparatus provided in the embodiment of the present application;

FIG. 4 is a schematic structural diagram of a transverse plate in the chromosome slide dropping device provided in the embodiment of the present application;

FIG. 5 is a schematic structural diagram of a support plate in the chromosome plating apparatus provided in the embodiment of the present application;

in the figure: 1. the supporting plate, 101, recess, 102, support bar, 103, shelves strip, 104, dog, 105, unloading hole, 2, supporting leg, 3, horizontal pole, 301, limiting plate, 4, material receiving box, 401, handle, 5, longeron, 501, spout, 6, supporting seat, 7, supporting wheel, 8, support column, 9, movable rod, 10, briquetting, 11, spring, 12, diaphragm, 121, draw-in groove, 122, lug, 123, baffle, 13, fixed cover, 14, clamp plate.

Detailed Description

The present invention will be described in further detail with reference to the accompanying drawings and specific embodiments. The embodiments of the present invention have been presented for purposes of illustration and description, and are not intended to be exhaustive or limited to the utility model in the form disclosed. Many modifications and variations will be apparent to those of ordinary skill in the art. The embodiment was chosen and described in order to best explain the principles of the utility model and the practical application, and to enable others of ordinary skill in the art to understand the utility model for various embodiments with various modifications as are suited to the particular use contemplated.

Referring to fig. 1-2, in the present embodiment, a chromosome slide dropping device is provided, which includes a supporting plate 1, supporting legs 2 are installed at four corners of the bottom end of the supporting plate 1, the lower ends of the supporting legs 2 are fixedly connected with a cross bar 3, a material receiving box 4 is arranged at the middle part of the cross bar 3, limiting plates 301 are fixedly connected to two sides of the material receiving box 4 of the cross bar 3, a handle 401 is installed on the box wall of the material receiving box 4, two ends of the cross bar 3 are fixedly connected with a longitudinal beam 5, a chute 501 is formed at the upper end of the longitudinal beam 5, a supporting base 6 is arranged at the upper end of the longitudinal beam 5, supporting wheels 7 are symmetrically installed at the bottom end of the supporting base 6, a supporting column 8 is fixedly connected to the upper end of the supporting base 6, a movable rod 9 in sliding connection is installed at the upper part of the supporting column 8, a plurality of material extruding structures are installed on the movable rod 9, a pressing block 10 is fixedly connected to one end of the movable rod 9 which is located at the outer side of the supporting column 8, a spring 11 is sleeved at a position between the supporting block 10, the supporting column 8 is positioned below the movable rod 9 and is fixedly connected with a transverse plate 12.

Referring to fig. 3 to 4, the material extruding structure includes a fixing sleeve 13, a pressing plate 14 is fixedly connected to the lower end of the fixing sleeve 13, the pressing plate 14 is L-shaped, a slot 121 for installing a dropper is formed in one side of the pressing plate 14 on the transverse plate 12, a protrusion 122 for clamping the dropper is formed on the inner wall of the slot 121, the upper portion of the dropper is located on one side of the pressing plate 14, a baffle 123 is formed in the other side of the dropper on the upper end of the transverse plate 12, the pressing plate 14 moves towards the baffle 123, and the pressing plate 14 and the baffle 123 extrude a rubber head of the dropper to realize dropping.

Referring to fig. 5, a groove 101 is formed at the upper end of the supporting plate 1, a plurality of supporting bars 102 are arranged in the groove 101, the supporting bars 102 are used for supporting the glass slide, so that the glass slide is in an inclined state, a plurality of retaining bars 103 are arranged between the plurality of supporting bars 102, one end of the glass slide is close to the retaining bars 103, a plurality of stoppers 104 are fixedly connected to the side walls of the retaining bars 103 close to the supporting bars 102, the stoppers 104 are used for positioning the glass slide, and a plurality of discharging holes 105 for discharging the reagent are formed in the middle of the supporting plate 1.

The working principle of the utility model is as follows:

when the device is used, one end of a glass slide is placed on the side wall of the blocking strip 103, the edge of the glass slide is close to the stop block 104, the other end of the glass slide is placed at the upper end of the supporting strip 102, the glass slide is inclined, so that the glass slide can be completely soaked in dye liquid when dyeing is carried out, the dye liquid is saved compared with the existing incubation box, the dye liquid flowing out of the glass slide flows into the groove 101 of the supporting plate 1, passes through the discharging hole 105 and falls into the material receiving box 4 for collection, the material receiving box 4 is pulled, the material receiving box 4 is taken out, and the material receiving box 4 is convenient to clean;

when dropping, the burette absorbs the dye liquor, insert the burette in draw-in groove 121, the rubber head of burette is located department between baffle 123 and the clamp plate 14, the lug 122 of draw-in groove 121 presss from both sides tightly the burette, promote support column 8, supporting wheel 7 removes in spout 501, the burette removes to corresponding slide glass top department, press down briquetting 10, movable rod 9 slides along support column 8, drive fixed cover 13 and clamp plate 14 and remove to baffle 123 direction, extrude the rubber head with clamp plate 14, the dye liquor flows out from the burette, fall on the slide glass, promote support column 8 once more, operate according to above-mentioned step, at another row slide glass dropping liquid, the design of this structure, improve the stability of dropping the piece, once to a plurality of slide glass dropping liquid, improve the efficiency of dropping liquid.

It is to be understood that the described embodiments are merely a few embodiments of the utility model, and not all embodiments. All other embodiments, which can be derived by one of ordinary skill in the art and related arts based on the embodiments of the present invention without any creative effort, shall fall within the protection scope of the present invention. Structures, devices, and methods of operation not specifically described or illustrated herein are generally practiced in the art without specific recitation or limitation.

Claims

1. The utility model provides a chromosome dripping device, includes backup pad (1), a serial communication port, supporting leg (2) are installed to the bottom four corners department of backup pad (1), supporting leg (2) lower extreme fixed connection horizontal pole (3), horizontal pole (3) middle part material receiving box (4), horizontal pole (3) are located the both sides department fixed connection limiting plate (301) of material receiving box (4), handle (401) are installed to the box wall of material receiving box (4), both ends fixed connection longeron (5) of horizontal pole (3), spout (501) have been seted up to longeron (5) upper end, longeron (5) upper end is equipped with supporting seat (6), supporting wheel (7) are installed to supporting seat (6) bottom symmetry, supporting seat (6) upper end fixed connection support column (8), sliding connection's movable rod (9) is installed on support column (8) upper portion, install a plurality of crowded material structures on movable rod (9), the movable rod (9) is located support column (8) outside one end fixed connection briquetting (10), and the department cover that the movable rod (9) is located between support column (8) and briquetting (10) is equipped with spring (11), and support column (8) are located fixed connection diaphragm (12) of movable rod (9) below department.

2. The chromosome dripping device according to claim 1, wherein the extruding structure comprises a fixing sleeve (13), a pressing plate (14) is fixedly connected to the lower end of the fixing sleeve (13), and the pressing plate (14) is arranged in an L shape.

3. The chromosome slide dropping device according to claim 1, wherein a clamping groove (121) for installing a dropping tube is formed in one side of the transverse plate (12) on the pressing plate (14), a convex block (122) for clamping the dropping tube is arranged on the inner wall of the clamping groove (121), the upper portion of the dropping tube is positioned on one side of the pressing plate (14), and a baffle plate (123) is arranged on the other side of the upper end of the transverse plate (12) on the dropping tube.

4. The chromosome plating device according to claim 1, wherein the supporting plate (1) is provided with a groove (101) at the upper end thereof, a plurality of supporting strips (102) are arranged in the groove (101), and the supporting strips (102) are used for supporting the slide glass.

5. The chromosome plating device according to claim 4, characterized in that a plurality of stopping strips (103) are arranged between the supporting strips (102), one end of the slide is close to the stopping strips (103), a plurality of stopping blocks (104) are fixedly connected to the side walls of the stopping strips (103) close to the supporting strips (102), and the stopping blocks (104) are used for positioning the slide.

6. The chromosome plating device according to claim 1, characterized in that a plurality of blanking holes (105) for leaking out reagents are opened in the middle of the supporting plate (1).