CN216363390U - Special embryo storage device of vitrification freeze thawing - Google Patents
Special embryo storage device of vitrification freeze thawing Download PDFInfo
- Publication number
- CN216363390U CN216363390U CN202122613288.8U CN202122613288U CN216363390U CN 216363390 U CN216363390 U CN 216363390U CN 202122613288 U CN202122613288 U CN 202122613288U CN 216363390 U CN216363390 U CN 216363390U
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- Prior art keywords
- storage box
- gear
- mounting plate
- box body
- liquid nitrogen
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- 210000001161 mammalian embryo Anatomy 0.000 title claims abstract description 36
- 238000004017 vitrification Methods 0.000 title claims abstract description 24
- 238000010257 thawing Methods 0.000 title claims abstract description 18
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims abstract description 96
- 239000007788 liquid Substances 0.000 claims abstract description 48
- 229910052757 nitrogen Inorganic materials 0.000 claims abstract description 48
- 230000007246 mechanism Effects 0.000 claims abstract description 25
- 238000007789 sealing Methods 0.000 claims abstract description 17
- 238000007710 freezing Methods 0.000 claims description 10
- 230000008014 freezing Effects 0.000 claims description 10
- 210000002257 embryonic structure Anatomy 0.000 abstract description 7
- 238000005516 engineering process Methods 0.000 description 5
- 230000009471 action Effects 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- 238000009434 installation Methods 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 210000004027 cell Anatomy 0.000 description 2
- 230000006835 compression Effects 0.000 description 2
- 238000007906 compression Methods 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 210000000287 oocyte Anatomy 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- 230000002411 adverse Effects 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000005779 cell damage Effects 0.000 description 1
- 208000037887 cell injury Diseases 0.000 description 1
- 230000005494 condensation Effects 0.000 description 1
- 238000009833 condensation Methods 0.000 description 1
- 238000005138 cryopreservation Methods 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 239000003595 mist Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 238000005086 pumping Methods 0.000 description 1
- 239000003507 refrigerant Substances 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
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- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The utility model discloses a vitrification freeze thawing special embryo storage device which comprises a mounting seat, wherein the top of the mounting seat is provided with a storage box body and a liquid nitrogen tank, the interior of the storage box body is provided with a mounting plate, the edge of the mounting plate is provided with a sealing strip, and the mounting plate is abutted against the inner wall of the storage box body through the sealing strip; a plurality of placing holes are uniformly formed in the mounting plate at intervals, storage pipes are arranged in the placing holes, two closed cover plates are arranged at the top of the storage box body, two pushing mechanisms are symmetrically arranged between each cover plate and the mounting plate along the width direction of the storage box body, and two supporting mechanisms are symmetrically arranged between the mounting plate and the bottom of the storage box body; the liquid nitrogen container sets up in the outside of storage box, is provided with the pump body between storage box and the liquid nitrogen container, and the liquid nitrogen container is connected with the input of the pump body through first pipe, and the inside of storage box is connected with the output of the pump body through the second pipe. The utility model not only has safe operation, but also is convenient for taking and placing embryos, and has strong practicability.
Description
Technical Field
The utility model belongs to the technical field of medical instruments, and particularly relates to a special embryo storage device for vitrification freezing and thawing.
Background
The vitrification freezing and thawing technology is a method for rapidly freezing cells or tissues, can avoid the formation of ice crystals in cells in the freezing and thawing process, furthest reduces cell damage, and makes great progress in the freezing and preserving of human gametes and embryos. In recent decades, vitrification freezing and thawing technology has been successfully applied to the cryopreservation of mature oocytes, immature oocytes, sperm and embryos at various developmental stages and has been reported to be used for the birth of healthy infants. The technology is simple, rapid and quick to operate, and is gradually becoming one of important application technologies in human assisted reproduction technology.
However, at present, human embryos need to be stored in the vitrification freeze thawing process, the most main refrigerant is liquid nitrogen, the liquid nitrogen is extremely low in temperature, extra care is needed during use, certain danger is brought to the whole operation process due to the fact that manual operation is needed, a large amount of fog can be generated in the storage device due to the existence of the liquid nitrogen, stored embryo information is difficult to distinguish, and unnecessary troubles are brought to medical workers.
The utility model patent with the patent publication number of CN 110024776A discloses a vitrification freeze-thawing special embryo storage device, which comprises a bottom plate, a tank body for storing liquid nitrogen and a freeze-thawing box for placing a vessel; the upper part of one side of the bottom plate is fixedly provided with an installation plate, a hoop is fixed above one side of the installation plate, a tank body for storing liquid nitrogen is arranged in the hoop in a sitting mode, the other side of the installation plate is provided with a pump body for pumping out the liquid nitrogen in the tank body, a freezing and thawing box is fixed on the bottom plate and is communicated with the tank body through a guide pipe, a sealing plate is arranged on the upper layer in the freezing and thawing box, the edge of the sealing plate is fixed with a sealing rubber strip, the sealing rubber strip is in interference fit with the inner wall of the freezing and thawing box, the sealing plate is provided with a plurality of cavities for placing medical utensils, the lower parts of two sides of the sealing plate are both fixed with a telescopic rod, and the lower part of the telescopic rod is in sealed sliding connection with an air cylinder, although the safety of operation can be improved through the technical scheme, the temperature of the liquid nitrogen is extremely low, and the air cylinder is used below 5 ℃, so that the adverse effect is brought to the action of the air cylinder due to the condensation of the moisture contained in the compressed air, the cylinder cannot be used, so that the effect of actually realizing the operation of lifting the sealing plate through the cylinder to bring convenience for taking and placing the medical vessel is not good.
SUMMERY OF THE UTILITY MODEL
The utility model aims to overcome the defects of the prior art and provide the special embryo storage device for vitrification freeze thawing.
In order to achieve the purpose, the utility model adopts the technical scheme that:
a vitrification is frozen and melted the specialized embryo storage device, including the mount pad, the top of the mount pad has storage tank and liquid nitrogen container, there are mounting panels in the storage tank, the edge of the mounting panel has sealing strips, the mounting panel is supported and contacted with the inner wall of the storage tank through the sealing strip;
a plurality of placing holes are uniformly formed in the mounting plate at intervals, storage pipes are arranged in the placing holes, two closed cover plates are arranged at the top of the storage box body, two pushing mechanisms are symmetrically arranged between each cover plate and the mounting plate along the width direction of the storage box body, and two supporting mechanisms are symmetrically arranged between the mounting plate and the bottom of the storage box body;
the liquid nitrogen container sets up in the outside of storage box, is provided with the pump body between storage box and the liquid nitrogen container, and the liquid nitrogen container is connected with the input of the pump body through first pipe, and the inside of storage box is connected with the output of the pump body through the second pipe.
Preferably, the pushing mechanism comprises a first rotating shaft, a first gear track, a second gear, a second rotating shaft, a second gear track, a conveying belt and a guide plate;
first gear track is seted up on the medial surface of apron along the length direction of apron, first pivot and second pivot rotate respectively through the bearing and set up in the top of storage box homonymy inside wall, first gear sets up in first pivot, first gear and the meshing of first gear track, the second gear sets up in the second pivot, first pivot and second pivot are passed through conveyer and are connected, the deflector sets up perpendicularly on the upper surface of mounting panel, the vertical setting of second gear track is on the side that is close to the second gear, second gear track and the meshing of second gear.
Preferably, the distance between the lowest point of the second gear and the top of the storage box body is 5-8 cm.
Preferably, each of the support mechanisms includes a first support rod, a restoring spring and a second support rod, the first support rod is vertically disposed on the inner wall of the bottom of the storage box, the second support rod is disposed above the first support rod, the top of the second support rod is vertically connected to the bottom of the mounting plate, the restoring spring is disposed between the first support rod and the second support rod, the bottom of the restoring spring is connected to the top of the first support rod, and the top of the restoring spring is connected to the bottom of the second support rod.
Preferably, a fixing seat matched with the bottom structure of the liquid nitrogen tank is arranged on the mounting seat.
Preferably, the first conduit is provided with a cock for controlling the flow of liquid nitrogen.
Preferably, a plurality of recording boxes are arranged on the mounting plate, the plurality of recording boxes correspond to the plurality of storage tubes one by one, and each recording box is positioned on the front side of the corresponding storage tube.
Preferably, four corners of the bottom of the mounting seat are respectively provided with universal wheels with locking functions.
Compared with the prior art, the utility model has the beneficial effects that:
(1) according to the vitrification freeze-thawing special embryo storage device, through the design of the pushing mechanism, the mounting plate can be moved upwards while the two cover plates are opened towards the two sides, the storage tube is driven to move upwards to the position, close to the box body opening, of the storage box body, so that an operator can conveniently put in or take out an embryo sample, the operation is convenient, the pushing mechanism does not contain an electrical element, and the operation cannot be influenced by the low temperature of liquid nitrogen;
(2) according to the utility model, mist generated by liquid nitrogen below the mounting plate can be blocked through the design of the mounting plate, so that an operator can quickly distinguish and store embryo information, the working pressure of the operator is reduced, and the danger brought by the liquid nitrogen is avoided;
(3) through the design of the supporting mechanism, the mounting plate can be supported, and the up-and-down movement of the mounting plate is more stable through the stretching and the compression of the recovery spring when the mounting plate rises or falls, so that the safety of the storage pipe is ensured;
(4) according to the utility model, through the design of the fixing seat, the placement stability of the liquid nitrogen tank can be improved, and the safety is improved.
Drawings
FIG. 1 is a schematic structural diagram of a vitrification freeze-thaw special-purpose embryo storage device provided by an embodiment of the present invention;
FIG. 2 is a schematic diagram of the internal structure of a vitrification freeze-thaw special-purpose embryo storage device provided by an embodiment of the present invention;
FIG. 3 is a bottom view of a cover plate in an embodiment of the present invention;
FIG. 4 is a top view of a mounting plate in an embodiment of the present invention;
FIG. 5 is a left side view of the connection of the mounting plate, the pushing mechanism and the cover plate in the embodiment of the present invention.
In the figure: 1. a mounting seat; 2. a storage box body; 3. a liquid nitrogen tank; 4. mounting a plate; 5. a sealing strip; 6. placing holes; 7. a storage tube; 8. a cover plate; 9. a pump body; 10. a first conduit; 11. a second conduit; 12. a first rotating shaft; 13. a first gear; 14. a first gear track; 15. a second gear; 16. a second rotating shaft; 17. A second gear track; 18. a conveyor belt; 19. a guide plate; 20. a first support bar; 21. a restoring spring; 22. a second support bar; 23. a fixed seat; 24. turning a valve; 25. a recording box; 26. a universal wheel.
Detailed Description
Exemplary embodiments of the present disclosure will be described in more detail below with reference to the accompanying drawings. While exemplary embodiments of the present disclosure are shown in the drawings, it should be understood that the present disclosure may be embodied in various forms and should not be limited to the embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete, and will fully convey the scope of the disclosure to those skilled in the art.
As shown in fig. 1 to 5, the vitrification freeze-thaw special embryo storage device provided by the embodiment of the present invention includes a mounting seat 1, a storage box 2 and a liquid nitrogen tank 3 are arranged on the top of the mounting seat 1, a mounting plate 4 is arranged inside the storage box 2, a sealing strip 5 is arranged on the edge of the mounting plate 4, and the mounting plate 4 is abutted against the inner wall of the storage box 2 through the sealing strip 5; the design of the sealing strip 5 not only can enable the mounting plate 4 to be sealed with the inner wall of the storage box body 2, avoid liquid nitrogen at the lower part of the storage box body 2 from contacting with air, but also can enable the mounting plate 4 to slide up and down.
A plurality of placing holes 6 are uniformly arranged on the mounting plate 4 at intervals, a storage pipe 7 is arranged in each placing hole 6, two closed cover plates 8 are arranged at the top of the storage box body 2, two pushing mechanisms are symmetrically arranged between each cover plate 8 and the mounting plate 4 along the width direction of the storage box body 2, and two supporting mechanisms are symmetrically arranged between the mounting plate 4 and the bottom of the storage box body 2; storage tube 7 is used for placing the embryo that needs freeze thawing, and apron 8 can keep warm to storage box 2, reduces storage box 2 upper portion and external environment's heat diffusion speed, and pushing mechanism is used for opening or the closed in-process at apron 8, drives mounting panel 4 and moves up or move down, realizes that the embryo takes conveniently.
The pushing mechanism comprises a first rotating shaft 12, a first gear 13, a first gear track 14, a second gear 15, a second rotating shaft 16, a second gear track 17, a conveying belt 18 and a guide plate 19; first gear track 14 is seted up on the medial surface of apron 8 along the length direction of apron 8, first pivot 12 and second pivot 16 rotate through the bearing respectively and set up in the top of storage box 2 homonymy inside wall, first gear 13 sets up on first pivot 12, first gear 13 meshes with first gear track 14, second gear 15 sets up on second pivot 16, first pivot 12 and second pivot 16 pass through conveyer 18 and connect, deflector 19 sets up perpendicularly on the upper surface of mounting panel 4, second gear track 17 is vertical to be set up on being close to the side of second gear 15, second gear track 17 meshes with second gear 15. When an embryo needs to be taken and placed, an operator pushes the two cover plates 8 to two sides, the first gear track 14 arranged below the two cover plates 8 moves to two sides to drive the first gear 13 meshed with the lower part of the two cover plates to rotate to drive the first rotating shaft 12 to rotate, further the conveying belt 18 is driven to rotate to drive the second rotating shaft 16 to rotate, so as to drive the second gear 15 to rotate, under the action of meshing force, the second gear track 17 meshed with the second gear 15 moves upwards to enable the guide plate 19 and the mounting plate 4 to move upwards, the storage pipe 7 gradually moves upwards along with the upward movement of the mounting plate 4, when the storage pipe 7 moves upwards to the top of the quick-distance storage box body 2, the two cover plates 8 are stopped to move, then the embryo is stored in the storage pipe 7 or taken out, after the embryo is put in or taken out, the two cover plates 8 are pushed inwards to close, so that all parts of the pushing mechanism move reversely, thereby moving the mounting plate 4 back down to the initial position.
The distance between the lowest point of the second gear 15 and the top of the storage box body 2 is 5-8 cm. Such design not only can be convenient for medical personnel to get and put the embryo, can also make storage tube 7 keep with the liquid nitrogen contact, improves storage tube 7's freeze thawing effect.
Each of the support mechanisms includes a first support rod 20, a restoring spring 21 and a second support rod 22, the first support rod 20 is vertically disposed on the inner wall of the bottom of the storage box 2, the second support rod 22 is disposed above the first support rod 20, the top of the second support rod 22 is vertically connected with the bottom of the mounting plate 4, the restoring spring 21 is disposed between the first support rod 20 and the second support rod 22, the bottom end of the restoring spring 21 is connected with the top of the first support rod 20, and the top end of the restoring spring is connected with the bottom of the second support rod 22. Can carry out auxiliary stay to mounting panel 4 through first bracing piece 20 and second bracing piece 22, resume spring 21 and can be under pushing mechanism's drive for mounting panel 4 can reciprocate, but also can provide a cushion effect for the upper and lower removal of mounting panel 4.
The mounting seat 1 is provided with a fixing seat 23 matched with the bottom structure of the liquid nitrogen tank 3. The design of fixing base 23 can support and spacing fixed liquid nitrogen container 3, can improve the steadiness of placing of liquid nitrogen container 3.
The first conduit 10 is provided with a tap 24 for controlling the flow of liquid nitrogen. Through a tap 24 for controlling the input and closing of the liquid nitrogen and for controlling the input flow of the input liquid nitrogen.
The mounting plate 4 is provided with a plurality of recording cartridges 25, the plurality of recording cartridges 25 are in one-to-one correspondence with the plurality of storage tubes 7, and each recording cartridge 25 is located on the front side of the corresponding storage tube 7. Through the design of record box 25, can put into the card that has the embryo storage information of record, the medical personnel of being convenient for distinguish and take.
Four corners of the bottom of the mounting base 1 are respectively provided with universal wheels 26 with locking function. When the embryo storage device provided by the embodiment of the utility model needs to be transferred, the mounting seat 1 is pushed to transfer the embryo storage device under the action of the universal wheel 26, and when the embryo storage device is transferred to a proper position, the universal wheel 26 is locked, so that random movement is avoided.
When the vitrification freeze-thaw special embryo storage device provided by the embodiment of the utility model is used, firstly, the rotary valve 24 and the pump body 9 are opened, liquid nitrogen enters the storage box body 2 through the first conduit 10 and the second conduit 11, after the liquid nitrogen is added, the rotary valve 24 and the pump body 9 are closed, then an operator pushes the two cover plates 8 towards two sides, the first gear track 14 arranged below the two cover plates 8 moves towards two sides, the first gear 13 meshed with the lower part of the first gear is driven to rotate, the first rotating shaft 12 is driven to rotate, the conveying belt 18 is further driven to rotate, the second rotating shaft 16 is driven to rotate, the second gear 15 is driven to rotate, under the action of meshing force, the second gear track 17 meshed with the second gear 15 moves upwards, the guide plate 19 and the mounting plate 4 move upwards, the storage tube 7 gradually moves upwards along with the mounting plate 4, when the storage tube 7 moves to the top of the storage box body 2 by a short distance, the two cover plates 8 stop moving, then the embryos are stored in the storage tube 7 or the embryos are taken out, after the embryos are placed in or taken out, the two cover plates 8 are pushed to the inner side to be closed, all parts of the pushing mechanism move in the opposite direction, and therefore the mounting plate 4 moves back to the initial position.
In summary, the vitrification freeze-thaw special embryo storage device provided by the embodiment of the utility model can move up the mounting plate by opening the two cover plates to both sides and simultaneously drive the storage tube to move up to the position of the storage box body close to the box body opening through the design of the pushing mechanism, so that an operator can conveniently put in or take out an embryo sample, the operation is convenient, and the pushing mechanism does not contain electrical elements, so that the operation is not influenced by the low temperature of liquid nitrogen; and can carry out the separation to the fog that the liquid nitrogen below the mounting panel produced through the design of mounting panel, can make operating personnel distinguish storage embryo information fast, reduce operating personnel's operating pressure, and avoided the danger that the liquid nitrogen brought, in addition, through supporting mechanism's design, not only can support the mounting panel, can also rise or when descending at the mounting panel, through the extension and the compression of recovery spring, make reciprocating of mounting panel more steady, ensured the security of storage pipe.
While embodiments of the utility model have been shown and described, it will be understood by those of ordinary skill in the art that: various changes, modifications, substitutions and alterations can be made to the embodiments without departing from the principles and spirit of the utility model, the scope of which is defined by the claims and their equivalents.
Claims (8)
1. The special embryo storage device for vitrification freezing and thawing is characterized by comprising a mounting seat (1), wherein the top of the mounting seat (1) is provided with a storage box body (2) and a liquid nitrogen tank (3), a mounting plate (4) is arranged inside the storage box body (2), a sealing strip (5) is arranged at the edge of the mounting plate (4), and the mounting plate (4) is abutted against the inner wall of the storage box body (2) through the sealing strip (5);
a plurality of placing holes (6) are uniformly formed in the mounting plate (4) at intervals, a storage pipe (7) is arranged in each placing hole (6), two closed cover plates (8) are arranged at the top of the storage box body (2), two pushing mechanisms are symmetrically arranged between each cover plate (8) and the mounting plate (4) along the width direction of the storage box body (2), and two supporting mechanisms are symmetrically arranged between each mounting plate (4) and the bottom of the storage box body (2);
the liquid nitrogen container (3) is arranged on the outer side of the storage box body (2), the pump body (9) is arranged between the storage box body (2) and the liquid nitrogen container (3), the liquid nitrogen container (3) is connected with the input end of the pump body (9) through a first guide pipe (10), and the inside of the storage box body (2) is connected with the output end of the pump body (9) through a second guide pipe (11).
2. The vitrification freeze thaw special embryo storage device according to claim 1, wherein the pushing mechanism comprises a first rotating shaft (12), a first gear (13), a first gear track (14), a second gear (15), a second rotating shaft (16), a second gear track (17), a conveyor belt (18), and a guide plate (19);
first gear track (14) are seted up on the medial surface of apron (8) along the length direction of apron (8), first pivot (12) and second pivot (16) rotate through the bearing respectively and set up in the top of storage box (2) homonymy inside wall, first gear (13) set up on first pivot (12), first gear (13) and first gear track (14) meshing, second gear (15) set up on second pivot (16), first pivot (12) and second pivot (16) are connected through conveyer (18), deflector (19) set up perpendicularly on the upper surface of mounting panel (4), second gear track (17) vertical setting is on the side that is close to second gear (15), second gear track (17) and second gear (15) meshing.
3. The vitrification freeze-thaw special embryo storage device according to claim 2, wherein the distance between the lowest point of the second gear (15) and the top of the storage box (2) is 5-8 cm.
4. The vitrification freeze-thaw special embryo storage device according to claim 1, wherein each of the support mechanisms comprises a first support rod (20), a restoring spring (21) and a second support rod (22), the first support rod (20) is vertically disposed on an inner wall of the bottom of the storage case (2), the second support rod (22) is disposed above the first support rod (20), the top of the second support rod (22) is vertically connected with the bottom of the mounting plate (4), the restoring spring (21) is disposed between the first support rod (20) and the second support rod (22), the bottom end of the restoring spring (21) is connected with the top of the first support rod (20), and the top end is connected with the bottom of the second support rod (22).
5. The vitrification freeze-thaw special embryo storage device according to claim 1, wherein a fixing seat (23) matching with the bottom structure of the liquid nitrogen tank (3) is arranged on the mounting seat (1).
6. The vitrification freeze-thaw special embryo storage device according to claim 1, wherein a cock (24) for controlling a flow rate of liquid nitrogen is provided on the first duct (10).
7. The vitrification freeze-thaw special embryo storage device according to claim 1, wherein a plurality of recording cartridges (25) are provided on the mounting plate (4), a plurality of the recording cartridges (25) correspond to a plurality of storage tubes (7) one by one, and each recording cartridge (25) is located at a front side of the corresponding storage tube (7).
8. The vitrification freeze-thaw special embryo storage device according to claim 1, wherein four corners of the bottom of the mounting base (1) are respectively provided with universal wheels (26) with locking function.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202122613288.8U CN216363390U (en) | 2021-10-28 | 2021-10-28 | Special embryo storage device of vitrification freeze thawing |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202122613288.8U CN216363390U (en) | 2021-10-28 | 2021-10-28 | Special embryo storage device of vitrification freeze thawing |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN216363390U true CN216363390U (en) | 2022-04-26 |
Family
ID=81246987
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202122613288.8U Expired - Fee Related CN216363390U (en) | 2021-10-28 | 2021-10-28 | Special embryo storage device of vitrification freeze thawing |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN216363390U (en) |
-
2021
- 2021-10-28 CN CN202122613288.8U patent/CN216363390U/en not_active Expired - Fee Related
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| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20220426 |