CN216349915U

CN216349915U - Liquid path system and device for detecting human secretion

Info

Publication number: CN216349915U
Application number: CN202121471725.0U
Authority: CN
Inventors: 郭海堂; 周聪; 黄继然; 刘剑
Original assignee: Shenzhen Reetoo Biotechnology Co Ltd
Current assignee: Shenzhen Reetoo Biotechnology Co Ltd
Priority date: 2021-06-30
Filing date: 2021-06-30
Publication date: 2022-04-19
Anticipated expiration: 2031-06-30

Abstract

The application relates to a liquid path system and a device for detecting human secretion, wherein the liquid path system comprises a cleaning pool; a stirring rod; the first pipeline is used for injecting cleaning liquid into the cleaning pool so as to clean the stirring rod; and the second pipeline is used for injecting diluent into the cleaning pool so as to wash away the cleaning liquid on the stirring rod. This application liquid way system can realize pouring into washing liquid and diluent into to wasing the pond to usable diluent washs the puddler.

Description

Liquid path system and device for detecting human secretion

Technical Field

The application belongs to the technical field of liquid path systems, and particularly relates to a liquid path system for human secretion.

Background

In the biochemical medical industry, it is often necessary to perform operations on fluids, such as the detection of human secretions. In the liquid path system, there is an operation that needs to stir by using the stirring rod, and the stirring rod needs to be cleaned by using a cleaning solution, and the cleaning solution remaining on the stirring rod after cleaning may affect a sample to be stirred.

SUMMERY OF THE UTILITY MODEL

The application provides a liquid way system and system for human secretion detects to this abluent puddler influences the problem of next sample among the solution prior art.

In order to solve the above technical problem, the present application provides a fluid path system for detecting human secretions, comprising: a cleaning tank; a stirring rod; the first pipeline is used for injecting cleaning liquid into the cleaning pool so as to clean the stirring rod; and the second pipeline is used for injecting diluent into the cleaning pool so as to wash away the cleaning liquid on the stirring rod.

In one embodiment, the fluid path system further comprises a switching assembly for switchably communicating the cleaning tank with the first or second line.

In one embodiment, the switching assembly comprises a first switching valve and a second switching valve, the fluid path system further comprises a third line, a fourth line, a fifth line and a first driver, the first pipeline is connected with a first liquid inlet end of the first switching valve, the second pipeline is connected with a second liquid inlet end of the first switching valve, the liquid outlet end of the first switching pipeline is communicated with the liquid outlet end of the second switching valve through the third pipeline, the fourth pipeline and the fifth pipeline are respectively connected with the first liquid outlet end and the second liquid outlet end of the second switching valve, the fourth pipeline is used for injecting the cleaning liquid or the diluent into the cleaning pool, the fifth pipeline is used for discharging the cleaning liquid or the diluent, the first driving piece is used for extracting the cleaning liquid through the first pipeline or extracting the diluent through the second pipeline.

In one embodiment, the driving member is connected to the third pipeline, and the first driving member is used for driving the cleaning solution or the diluent to flow between the first switching valve and the second switching valve.

In one embodiment, the fluid path system further comprises an elution needle connected to the fifth conduit.

In one embodiment, the fluid path system further comprises a second driving member connecting the stirring rod and the elution needle to drive the stirring rod and the elution needle to move simultaneously.

In order to solve the technical problem, the present application provides an apparatus for detecting human body secretions, which includes the above liquid path system.

In one embodiment, the apparatus further comprises a first station to which the elution needle is movable, a second station to which the agitator arm is movable.

In one embodiment, the first station and the second station are arranged side by side.

In one embodiment, the device further comprises a transportation mechanism, wherein the transportation mechanism is used for sequentially transporting the test tubes to a first station and a second station, the elution needle is used for adding diluent to the test tube positioned at the first station, and the stirring rod is used for stirring the test tube positioned at the second station.

Be different from prior art, this application liquid way system includes the puddler for human secretion and diluent are mixed in the stirring. The system also comprises a cleaning pool, a first pipeline and a second pipeline, wherein the first pipeline is used for injecting cleaning liquid into the cleaning pool so as to clean the stirring rod; the second pipeline is used for injecting the diluent into the cleaning pool for wash away the cleaning liquid on the puddler, uses the diluent to clean the puddler, can avoid remaining cleaning liquid on the puddler to treat to stir the sample and produce the influence.

Drawings

The above and other objects, features and advantages of exemplary embodiments of the present disclosure will become readily apparent from the following detailed description read in conjunction with the accompanying drawings. Several embodiments of the present disclosure are illustrated by way of example, and not by way of limitation, in the figures of the accompanying drawings and in which like reference numerals refer to similar or corresponding parts and in which:

fig. 1 is a schematic structural diagram of an embodiment of a fluid path system for detecting human secretions according to the present application.

Description of the main reference numerals:

100-a liquid path system, 11-a cleaning pool, 12-a stirring rod, 13-an elution needle, 14-a first pipeline, 15-a second pipeline, 16-a third pipeline, 17-a fourth pipeline, 18-a fifth pipeline, 21-a first switching valve, 22-a second switching valve and 23-a first driving piece.

Detailed Description

The technical solutions in the embodiments of the present disclosure will be clearly and completely described below with reference to the drawings in the embodiments of the present disclosure, and it is obvious that the described embodiments are some, but not all embodiments of the present disclosure. All other embodiments, which can be derived by a person skilled in the art from the embodiments disclosed herein without making any creative effort, shall fall within the protection scope of the present disclosure.

Specific embodiments of the present disclosure are described in detail below with reference to the accompanying drawings.

Referring to fig. 1, fig. 1 is a schematic structural diagram of an embodiment of a fluid path system for detecting human secretions according to the present application. The fluid path system 100 of the present embodiment includes a cleaning tank 11, a stirring rod 12, a first pipeline 14, and a second pipeline 15. The fluid path system 100 is used for supporting the sample adding detection of human secretion and the stirring operation during the sample adding detection.

The stirring rod 12 can be made of glass, and the stirring rod made of glass cannot be influenced by liquid such as human secretion and is convenient to use. The stirring bar 12 is cleaned in the cleaning tank after completion of the stirring.

Therefore, the fluid path system 100 includes a cleaning tank 11, the cleaning tank 11 is communicated with a first pipeline 14, and the first pipeline 14 inputs cleaning fluid to the cleaning tank to wash the stirring rod 12 and clean the stirring rod 12. The cleaning pool 11 is also communicated with a second pipeline 15, and the second pipeline 15 injects diluent into the cleaning pool 11 and can also be used for cleaning the stirring rod 12.

During use of the entire fluid path system 100, the stirring rod 12 may be cleaned with a cleaning fluid or a diluting fluid. In an embodiment, after the stirring rod stirs the sample, the sample needs to enter the cleaning pool for cleaning, and if the stirring rod 12 is cleaned by using the cleaning solution, the cleaning solution remains on the stirring rod, so that when the dilution solution is reused for cleaning, not only the residue after stirring the human secretion can be cleaned, but also the residual cleaning solution can be cleaned. In another embodiment, after the stirring rod stirs the sample, the sample needs to enter the washing pool for washing, the stirring rod 12 in the washing pool is washed by using a diluent, and before the liquid path system needs to stop working (i.e. the stirring rod stirs a plurality of samples in sequence within a certain time period), the stirring rod 11 in the washing pool needs to be washed by using a washing liquid, so as to further ensure the washing effect; when the liquid path system needs to work again, because a certain amount of cleaning liquid remains on the stirring rod 11, and the cleaning liquid may affect the activity of the human body secretion sample, when the liquid path system needs to work again, the cleaning liquid remaining on the stirring rod 11 needs to be washed by using a diluent to wash away the cleaning liquid remaining on the stirring rod, that is, the cleaning pool 11 is also communicated with the second pipeline 15, and the second pipeline 15 injects the diluent into the cleaning pool 11 to wash the stirring rod 12. When the dilution liquid is used for sample adding detection of the human secretion by the liquid path system, the dilution liquid is added into the human secretion, namely, the dilution liquid is used for diluting the human secretion to obtain the human secretion with lower concentration, so that the test is better carried out. In order not to affect the characteristics of the human body secretion, physiological saline can be adopted, and the activity of the human body secretion is not reduced.

Corresponding to the structure of the liquid path system 100 of the present embodiment, the cleaning liquid is injected into the cleaning tank 11 through the first pipeline 14 to clean the stirring rod 12, and the diluent is injected into the cleaning tank 11 through the second pipeline 15 to wash away the cleaning liquid on the stirring rod 12 with the diluent. The first and

second pipes

14 and 15 may be of a hose structure, which facilitates flexible arrangement of the entire fluid path system.

In this embodiment, the fluid path system 100 further includes a switching component, which can switch the cleaning tank 11 to communicate with the first pipeline 14 or the second pipeline 15. The cleaning tank 11 is communicated with different pipelines in different processes, is communicated with the first pipeline 14 in a cleaning solution cleaning process, and is communicated with the second pipeline 15 in a process of washing away the cleaning solution by the diluent.

The liquid path system 100 further includes an elution needle 13 for adding a diluent to the human body secretion sample, the second pipeline 15 communicates with the elution needle 13 to input the diluent to the elution needle 13, at this time, the diluent can realize the function of an eluent, and the elution needle 13 can adopt a needle-shaped structure so as to add the diluent to a test tube in which the human body secretion is located.

In addition, in the case of the elution needle 13, there may be a problem that the diluent is deposited and blocked in the elution needle 13 when it is used for multiple times (for example, when the diluent is physiological saline, the physiological saline in the elution needle is easy to crystallize due to volatilization), so that the elution needle needs to be cleaned with a cleaning solution after each use, that is, the first pipeline 14 is also communicated to the elution needle 13 in this embodiment. The first line 14 supplies a cleaning liquid to the elution needle 13 to clean the elution needle 13.

Further, the first pipeline 14 is switchably connected to the elution needle 13 and/or the washing tank, and the second pipeline 15 is switchably connected to the elution needle 13 and/or the washing tank, which may be also switchably connected by a switching assembly.

To the washing of elution needle 13 to and the washing away of puddler 12, all can produce the waste liquid, adopt in this embodiment to wash pond 11 and collect the waste liquid, puddler 12 and elution needle 13 all set up in the top of wasing pond 11, and the washing liquid of draining into washing pond 11 can be used to wash away puddler 12, washs elution needle 13, also can directly discharge into by elution needle 13 exhaust liquid and wash pond 11. The cleaning tank 11 may be a plastic bucket, a glass box, or the like. Further, the waste liquid in the washing tank 11 can be discharged using a pipe communicating with the washing tank 11.

The switching components in the fluid path system 100 of this embodiment specifically include a first switching valve 21 and a second switching valve 22. The first switching valve 21 and the second switching valve 22 both have two paths to realize switching, specifically, the first switching valve 21 includes a liquid outlet end, a first liquid inlet end a and a second liquid inlet end b, and the second switching valve 22 includes a liquid inlet end, a first liquid outlet end c and a second liquid outlet end d.

The fluid circuit system 100 further includes a third, fourth and

fifth circuit

16, 17, 18 to enable communication between the switching assembly and other components. The third, fourth and

fifth lines

16, 17, 18 may also be hoses.

The first pipeline 14 is connected to the second liquid inlet end b of the first switching valve 21, the second pipeline 15 is connected to the first liquid inlet end a of the first switching valve 21, the liquid outlet end of the first switching valve 21 is communicated with the liquid inlet end of the second switching valve 22 through the third pipeline 16, the fourth pipeline 17 and the fifth pipeline 18 are respectively connected to the first liquid outlet end c and the second liquid outlet end d of the second switching valve 22, the fourth pipeline 17 is used for injecting cleaning liquid or diluent into the cleaning pool 11, and the fifth pipeline 18 is used for discharging the cleaning liquid or diluent. The elution needle 13 is specifically connected with the liquid outlet end of the fifth pipeline 18.

The switching function is realized by switching on different communication ends of the first switching valve 21 and the second switching valve 22. The cleaning liquid enters the elution needle 13 through the second liquid inlet end b and the first liquid outlet end c to clean the elution needle 13; the second liquid outlet end d can enter the cleaning pool 11 through the second liquid inlet end b to wash and clean the stirring rod 12.

The diluent enters the elution needle 13 through the first liquid inlet end a and the first liquid outlet end c so as to add the diluent to the secretion of the human body; the water can enter the cleaning pool 11 through the first liquid inlet end a and the second liquid outlet end d to wash the stirring rod 12.

The specific fluid path system 100 further includes a controller, and the controller can control the first switching valve 21 to switch between the first fluid inlet end a and the second fluid inlet end b, and control the second switching valve 22 to switch between the first fluid outlet end c and the second fluid outlet end d. The controller may be a switching structure, for example, the switching valve is an electromagnetic valve, and the switching control is realized by itself.

In the embodiment, the first driving member 23 is arranged between the first switching valve 21 and the second switching valve 22 to perform the extraction operation on the cleaning liquid and the diluent, i.e. only one driving member needs to be arranged in the whole liquid path system, so that the cost of the power source pump body can be reduced. The first drive element 23 draws in particular cleaning fluid through the first line 14 or diluent through the second line 15. Which is connected to the third piping 16 for driving the cleaning liquid or the diluting liquid to flow between the first switching valve 21 and the second switching valve 22 to flow to different positions by switching control of the first switching valve 21 and the second switching valve 22.

The first driving member 23 in this embodiment is a peristaltic pump comprising a drive, a pump head and a flexible tube, which pumps a fluid by alternately squeezing and releasing the flexible delivery tube of the pump, wherein the fluid only contacts the flexible tube and not the pump head, and is substantially contamination free. And the peristaltic pump has good sealing performance, does not need a switching valve and a sealing element, and is simple to maintain.

The liquid path system of the embodiment comprises a stirring rod which is used for stirring and mixing the human secretion and the diluent. The system also comprises a cleaning pool, a first pipeline and a second pipeline, wherein the first pipeline is used for injecting cleaning liquid into the cleaning pool so as to clean the stirring rod; the second pipeline is used for injecting the diluent into the cleaning pool for wash away the cleaning liquid on the puddler, uses the diluent to clean the puddler, can avoid remaining cleaning liquid on the puddler to treat to stir the sample and produce the influence.

Based on the above liquid path system, the present application further provides a device for detecting human body secretions, which includes the above liquid path system 100. After the device detects a plurality of human secretion samples for a period of time, the device needs to be shut down (a liquid path system also needs to stop working when the device is shut down), generally, before the device is shut down, the stirring rod 13 and parts or pipelines contacting with the samples need to be cleaned by cleaning liquid, namely, the cleaning liquid can be injected into the cleaning pool 11 through the first pipeline 14 so as to clean the stirring rod 12 in the cleaning pool 11; therefore, after cleaning, a part of the cleaning liquid remains on the stirring rod. Therefore, after the apparatus is restarted, the diluent is injected into the cleaning pool 11 through the second pipeline 15 to wash away the residual cleaning solution on the stirring rod 12, so as to avoid affecting the sample to be stirred.

The device also comprises a first station and a second station, the elution needle 13 can move to the first station, and the stirring rod 12 can move to the second station. Human secretion is transported to first station and second station in proper order, specifically can adopt the test tube to hold human secretion, and when the test tube was located first station, control elution needle 13 was carried out the application of sample to it at first station. When the test tube is located at the second station, the stirring rod 12 is controlled to stir the test tube at the second station. For the test tube is stabilized on the station, first station and second station can set up the structure into the test-tube rack.

The first station and the second station are arranged side by side to realize the assembly line type transmission. For example, the first test tube and the second test tube can also be transported side by side, and when the first test tube is transported from the first station to the second station, the second test tube is also transported to the first station at the same time.

Still include transport mechanism in the device, transport mechanism is used for transporting first station and second station with the test tube in proper order, and transport mechanism can press from both sides and get the test tube and shift, also can be the transport structure who sets up on the test-tube rack, and the removal of test-tube rack has realized the test tube promptly and has moved different positions. The elution needle adds the diluent to the test tube of first station, and the puddler then stirs to the test tube of second station.

The liquid path system 100 further comprises a second driving member, and the second driving member can drive the stirring rod 12 and the elution needle 13 to move simultaneously, namely, drive to the working position simultaneously to operate on the human secretion, so as to form an assembly line type operation. And before driving to the station, the last two steps are to convey the diluent, wash the stirring rod 12 with the diluent, and input the diluent to the elution needle 13. The second driving member may specifically include a clamping portion for clamping the agitating bar 12 and the elution needle 13, a moving portion for driving the clamping portion to move, and a stirring portion for driving the clamped agitating bar 12 to stir.

On the one hand, when the stirring rod 12 stirs the test tube located at the second station, the driving part drives the stirring rod 12 to stir, so that the sample on the cotton swab in the test tube is eluted into the test tube. On the other hand, after the agitating bar 12 is retracted into the washing tub 11 by the moving part, the agitating part drives the agitating bar 12 to agitate in the washing tub 11 to improve the washing effect.

Corresponding to the process of sample adding and stirring, when a first test tube comes to a first station, the elution needle 13 moves to the position above the first station (at the moment, the position above the first test tube), and a preset diluent is sprayed on the first test tube;

the first test tube moves to the second station again, and the stirring rod 12 stirs the liquid in the first test tube so as to elute the sample on the cotton swab in the first test tube into the first test tube;

when the puddler 12 moved to first test tube and stirs the elution, the second test tube came to first station, and elution needle 13 removed to first station top (this moment is second test tube top) and spouts predetermined diluent to the second test tube.

The elution needle 13 and the stirring rod 12 are retracted to the upper part of the cleaning pool together, and the diluent enters the cleaning pool to realize the washing of the stirring rod 12.

This embodiment uses two diverter valves and a driving piece to realize all can be to the transport in two places of diluent and washing liquid, adopts low-cost structure can realize the application of sample stirring to human secretion, also can realize the washing to elution needle and puddler, and can guarantee to wash and do not influence and wait to stir the sample.

In the above description of the present specification, the terms "fixed," "mounted," "connected," or "connected," and the like, are to be construed broadly unless otherwise expressly specified or limited. For example, with the term "coupled", it can be fixedly coupled, detachably coupled, or integrally formed; can be mechanically or electrically connected; they may be directly connected or indirectly connected through intervening media, or they may be connected internally or in any other suitable relationship. Therefore, unless the specification explicitly defines otherwise, those skilled in the art can understand the specific meaning of the above terms in the present application according to specific circumstances.

From the above description of the present specification, those skilled in the art will also understand the terms used below, terms indicating orientation or positional relationship such as "upper", "lower", "front", "rear", "left", "right", "length", "width", "thickness", "vertical", "horizontal", "top", "bottom", "inner", "outer", "axial", "radial", "circumferential", "central", "longitudinal", "transverse", "clockwise" or "counterclockwise" and the like are based on the orientation or positional relationship shown in the drawings of the present specification, it is used for convenience in explanation of the disclosure and for simplicity in description, and does not explicitly show or imply that the devices or elements involved must be in the particular orientation described, constructed and operated, therefore, the above terms of orientation or positional relationship should not be interpreted or construed as limiting the present application.

In addition, the terms "first" or "second", etc. used in this specification are used to refer to numbers or ordinal terms for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include at least one of the feature. In the description of the present specification, "a plurality" means at least two, for example, two, three or more, and the like, unless specifically defined otherwise.

While various embodiments of the present application have been shown and described herein, it will be obvious to those skilled in the art that such embodiments are provided by way of example only. Numerous modifications, changes, and substitutions will occur to those skilled in the art without departing from the spirit and scope of the present application. It should be understood that various alternatives to the embodiments of the application described herein may be employed in practicing the application. The following claims are intended to define the scope of the application and, accordingly, to cover module compositions, equivalents, or alternatives falling within the scope of these claims.

Claims

1. A fluid path system for detection of human secretions, the fluid path system comprising:

a cleaning tank;

a stirring rod;

the first pipeline is communicated with the cleaning pool and used for injecting cleaning liquid into the cleaning pool so as to clean the stirring rod when the stirring rod enters the cleaning pool;

and the second pipeline is communicated with the cleaning pool and used for injecting diluent into the cleaning pool so as to wash away the cleaning liquid on the stirring rod.

2. The fluid path system of claim 1, further comprising a switching assembly for switchably communicating the cleaning basin to the first or second conduits.

3. The fluid path system of claim 2, wherein the switching assembly comprises a first switching valve and a second switching valve, the liquid path system also comprises a third pipeline, a fourth pipeline, a fifth pipeline and a first driving piece, the first pipeline is connected with a first liquid inlet end of the first switching valve, the second pipeline is connected with the second liquid inlet end of the first switching valve, the liquid outlet end of the first switching valve is communicated with the liquid inlet end of the second switching valve through the third pipeline, the fourth pipeline and the fifth pipeline are respectively connected with the first liquid outlet end and the second liquid outlet end of the second switching valve, the fourth pipeline is used for injecting the cleaning liquid or the diluent into the cleaning pool, the fifth pipeline is used for discharging the cleaning liquid or the diluent, the first driving piece is used for extracting the cleaning liquid through the first pipeline or extracting the diluent through the second pipeline.

4. The fluid path system of claim 3, wherein the first driver is connected to the third line, the first driver being configured to drive the flow of the cleaning fluid or the diluent between the first switching valve and the second switching valve.

5. The fluid path system of claim 3, further comprising an elution needle connected to the fifth conduit.

6. The fluid path system of claim 5, further comprising a second drive connecting the agitator bar and the elution needle to drive simultaneous movement of the agitator bar and the elution needle.

7. An apparatus for detection of human secretions, characterized in that it comprises a liquid path system according to any of claims 1 to 6.

8. The apparatus of claim 7, further comprising a first station, a second station, and an elution needle, the elution needle being movable to the first station, the agitator bar being movable to the second station.

9. The apparatus of claim 8, wherein the first station and the second station are disposed side-by-side.

10. The apparatus according to claim 8, further comprising a transport mechanism for transporting test tubes to the first and second stations in sequence, the elution needle for adding diluent to the test tube at the first station, and the stirring rod for stirring the test tube at the second station.