CN216349783U - Fixed sampling instrument for medicinal soft capsules - Google Patents

Fixed sampling instrument for medicinal soft capsules Download PDF

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Publication number
CN216349783U
CN216349783U CN202122862944.8U CN202122862944U CN216349783U CN 216349783 U CN216349783 U CN 216349783U CN 202122862944 U CN202122862944 U CN 202122862944U CN 216349783 U CN216349783 U CN 216349783U
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capsule
sample
sampling
fixed
thing platform
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CN202122862944.8U
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Chinese (zh)
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郑新元
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Tianjin Institute Of Drug Control
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Tianjin Institute Of Drug Control
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Abstract

The utility model discloses a fixed sampling instrument for medicinal soft capsules, which comprises a sampling operation table and a sampling object placing table, wherein the sampling object placing table is arranged above the sampling operation table, a lifting device is arranged between the sampling object placing table and the sampling operation table and used for driving the sampling object placing table to move up and down, and a capsule fixing device is arranged on the sampling object placing table and used for fixing soft capsules of different shapes. The utility model provides a medicinal soft capsule fixing and sampling instrument, which is suitable for fixing soft capsules in various shapes; the soft capsule can be fixed on an instrument, so that the sampling operation is convenient, and the operation is simple, convenient, sterile and efficient; the soft capsule can have the functions of uniformly mixing the contents and cleaning under the pushing of the lifting device; the utility model has the advantages of simple and convenient sampling, accurate weighing, multiple functions and improvement of working efficiency and accuracy.

Description

Fixed sampling instrument for medicinal soft capsules
Technical Field
The utility model belongs to the technical field of medical instruments, and particularly relates to a fixed sampling instrument for a medicinal soft capsule.
Background
The medicine soft capsule is a very common oral medicine preparation in medicines, and is a capsule prepared by directly sealing a certain amount of liquid raw material medicines or dissolving or dispersing solid raw material medicines in proper auxiliary materials to prepare solution, suspension, emulsion or semisolid and sealing the solution, the suspension, the emulsion or the semisolid in a soft capsule material. The soft capsule wall material is generally prepared by singly or mixing gelatin, glycerin or other suitable pharmaceutical excipients for capsules. Common shapes include spherical, elliptical, tubular, fish-shaped, and more irregular shapes.
In the detection of the soft capsule, the requirements of content, components, microorganisms and the like of the medicine are required to be detected according to the standard of Chinese pharmacopoeia. In order to meet the requirements, the capsule content needs to be extruded and then subjected to a plurality of operation steps of sampling, uniformly mixing, weighing, cleaning and the like. However, in the traditional operation process, the content of the capsule is squeezed out by bare hands of an operator or medical tweezers, and the like, so that the medicine is often leaked to pollute hands or the external environment, and a link violating the aseptic operation principle exists. Meanwhile, in actual work, due to the fact that the medicine sampling amount is large, the operations need to be repeated for multiple times, the situations that the working efficiency is low, the medicine weighing is inaccurate and the like occur, and the accuracy and the timeliness of the medicine inspection report are further seriously affected.
SUMMERY OF THE UTILITY MODEL
In order to solve the technical problem, the utility model provides a fixed sampling instrument for medicinal soft capsules.
The utility model provides a fixed appearance of taking a sample of medicinal softgel, includes the sample operation platform and takes a sample to put the thing platform, the sample is put the thing platform and is located the top of sample operation platform, the sample is put and is equipped with elevating gear between thing platform and the sample operation platform, elevating gear is used for driving the thing platform reciprocates is put in the sample, the sample is put and is equipped with capsule fixing device on the thing platform, capsule fixing device is used for fixing the softgel of different shapes.
Above technical scheme is preferred, capsule fixing device includes that capsule stiff end and capsule move the end, the capsule stiff end is fixed the left side of putting the thing platform in the sample, the capsule moves the end and locates the right side of capsule stiff end, the capsule move the end can for the capsule stiff end removes about, capsule stiff end and capsule move and are equipped with the spring between the end.
Above technical scheme is preferred, the capsule stiff end includes head rod and first mounting panel, the lower extreme of head rod with the thing platform is connected in the sample, the upper end of head rod with the first mounting panel is connected, the center department of first mounting panel is equipped with aperture adjustable connecting hole.
Above technical scheme is preferred, the capsule removes the end and includes second connecting rod and second mounting panel, the lower extreme of second connecting rod with the thing platform sliding connection is put in the sample, the upper end of second connecting rod with the second mounting panel is connected, the center department of second mounting panel is equipped with aperture adjustable connecting hole.
Above technical scheme is preferred, elevating gear includes two electro-hydraulic pressure lifter, the stiff end of electro-hydraulic pressure lifter with the sample operation panel is connected, the removal end of electro-hydraulic pressure lifter with the thing platform is connected in the sample.
Above technical scheme is preferred, the front side of sample operation panel is equipped with the control the switch module of elevating gear work.
The utility model has the advantages and positive effects that: the utility model provides a medicinal soft capsule fixing and sampling instrument, which is suitable for fixing soft capsules in various shapes; the soft capsule can be fixed on an instrument, so that the sampling operation is convenient, and the operation is simple, convenient, sterile and efficient; the soft capsule can have the functions of uniformly mixing the contents and cleaning under the pushing of the lifting device; the utility model has the advantages of simple and convenient sampling, accurate weighing, multiple functions and improvement of working efficiency and accuracy.
Drawings
FIG. 1 is a front view of a fixed sampling instrument for soft pharmaceutical capsules according to an embodiment of the present invention;
FIG. 2 is a front view of the lifting device and the sample stage according to an embodiment of the present invention;
fig. 3 is a left side view of the fixed sampling instrument for soft capsules according to an embodiment of the present invention.
Wherein: 1. a sampling console; 2. a sampling object placing table; 3. a spring; 4. a first connecting rod; 5. a first mounting plate; 6. connecting holes; 7. a second connecting rod; 8. a second mounting plate; 9. an electro-hydraulic lifter; 10. a switch; 11. a speed regulating switch; 12. a site switch; 13. and (4) making capsules.
Detailed Description
It should be noted that the embodiments and features of the embodiments may be combined with each other without conflict.
The present invention will be described in detail below with reference to the embodiments with reference to the attached drawings.
This embodiment is to lacking the current situation of dedicated softgel sampling equipment in clinical and proposes, and this embodiment provides a fixed appearance of taking a sample of medicinal softgel, as shown in fig. 1-3, put thing platform 2 including sample operation panel 1 and sample, the thing platform is located in the sample the top of sample operation panel, the sample is put and is equipped with elevating gear between thing platform and the sample operation panel, elevating gear is used for driving the sample is put the thing platform and is reciprocated, the sample is put and is equipped with capsule fixing device on the thing platform, capsule fixing device is used for the softgel of fixed different shapes.
Specifically, capsule fixing device includes that capsule stiff end and capsule move the end, the capsule stiff end is fixed the left side of putting the thing platform in the sample, the capsule moves the end and locates the right side of capsule stiff end, the capsule move the end can for the capsule stiff end removes about, be equipped with spring 3 between capsule stiff end and the capsule removal end. During operation, the soft capsule is fixed between the fixed end and the movable end of the capsule by the tension of the spring.
Further, the capsule stiff end includes head rod 4 and first mounting panel 5, the lower extreme of head rod with the thing platform is connected in the sample, the upper end of head rod with first mounting panel is connected, the center department of first mounting panel is equipped with aperture adjustable connecting hole 6. The aperture of the connecting hole is adjustable, so that the soft capsules with different diameters can be adapted. Optionally, the connecting hole is formed by two or three arc-shaped plates which are in a circular hole shape and provided with a notch, and a spring is arranged between the arc-shaped plates and the first mounting plate, so that the size of the aperture of the connecting hole is adjusted.
Further, the capsule removes the end and includes second connecting rod 7 and second mounting panel 8, the lower extreme of second connecting rod with the thing platform sliding connection is put in the sample, the upper end of second connecting rod with the second mounting panel is connected, the center department of second mounting panel is equipped with aperture adjustable connecting hole 6. The aperture of the connecting hole is adjustable, so that the soft capsules with different diameters can be adapted. Optionally, the connecting hole is formed by two or three arc-shaped plates which are in a circular hole shape and provided with a notch, and a spring is arranged between the arc-shaped plates and the second mounting plate, so that the size of the aperture of the connecting hole is adjusted. Optionally, the slider can be arranged below the second connecting plate, the sampling storage platform is provided with a slide way in the left-right direction, one end of the spring is connected with the first connecting rod, and the other end of the spring is connected with the second connecting rod.
Specifically, elevating gear includes two electro-hydraulic pressure lifter 9, the stiff end of electro-hydraulic pressure lifter with the sample operation panel is connected, the removal end of electro-hydraulic pressure lifter with the thing platform is connected in the sample. The two electro-hydraulic lifting rods vibrate up and down at a certain frequency to uniformly mix the capsule contents. The electro-hydraulic lifting rod can also be replaced by a vibration table with a vibration motor or an electric push rod and the like.
Specifically, the front side surface of the sampling operation platform is provided with a switch assembly for controlling the lifting device to work. The switch assembly comprises a switch 10, a speed regulating switch 11 and a position switch 12, wherein the switch is turned on, the electric hydraulic lifting rod works, the speed regulating switch is used for regulating the lifting speed, and the position switch is used for regulating the lifting height.
In operation, the capsule 13 is fixed between the fixed end and the movable end of the capsule, the fixed end and the movable end of the capsule are connected by a spring, and the capsule is fixed between the fixed end and the movable end of the capsule by the tension of the spring. And according to the different sizes of capsule diameter, the aperture of the connecting hole of capsule stiff end and capsule removal end can be carried out manual regulation.
If routine detection items are carried out, the capsule can be fixed, a needle is directly inserted from the moving end of the capsule by a special sampling gun, the wall of the capsule is punctured, a certain amount of capsule content is extracted and injected into a specific container, and then the next component and content analysis is carried out. After the embodiment is applied, the possibility that the content of the capsule is infected with the hands of an experimenter is reduced, and the pollution to the external environment is reduced.
If content analysis is carried out, the operation needs to be carried out for tens of times or even hundreds of times, and according to the traditional sampling method, the capsule is held by hands, no efficient tool is used, the sampling is difficult, and time and labor are wasted. After the embodiment is adopted, the sampling efficiency can be greatly improved, the experimental error is reduced, and the measurement accuracy and timeliness are improved.
If the weight detection items such as capsules need to be carried out, the top end of the capsule can be cut open by a blade after the capsule is fixed, a sampling gun is inserted from the moving end of the capsule, the content of the capsule is fully absorbed, and the capsule is injected into a specific container for weighing. And (4) absorbing the organic solvent by using the sampling gun again, injecting the organic solvent into the capsule, fully washing the residual content, completely absorbing the content, repeating the steps for a plurality of times until the content is completely removed, and transferring the capsule into a drying and ventilating cabinet for natural air drying. After the embodiment is adopted, the sampling efficiency can be greatly improved, the experimental error is reduced, and the measurement accuracy and timeliness are improved.
If the microorganism detection project is carried out, the capsule can be fixed, the surface of the capsule is disinfected, a needle is inserted from the moving end of the capsule by using a sterile sampling gun, the wall of the capsule is punctured, a certain amount of capsule content is extracted and injected into a specific sterile container, and then the next step of microorganism analysis is carried out. After the embodiment is applied, the pollution of external microorganisms to the content of the capsule is avoided, and the inspection accuracy is improved.
Optionally, in this embodiment, the overall length of the sampling console is 15cm, the overall width of the console is 12cm, and the overall height of the console =12 cm. The height between the upper plane of the sampling operation platform and the sampling object placing platform is 3 cm; the distance between the two electric hydraulic lifting rods is 4 cm; the outer diameter of the first mounting plate and the second mounting plate is 1.2cm, the initial inner diameter of the connecting hole is 0.6cm, and manual adjustment can be carried out according to the diameter of the capsule. The distance between the first connecting rod and the second connecting rod and the sampling object placing table is 1 cm; the thickness of the sampling object placing table is 0.5 cm; the diameter of the electro-hydraulic rod is 0.8 cm. The size of each part is not particularly limited, and the size can be adaptively designed according to actual conditions.
The utility model has the advantages and positive effects that: the utility model provides a medicinal soft capsule fixing and sampling instrument, which is suitable for fixing soft capsules in various shapes; the soft capsule can be fixed on an instrument, so that the sampling operation is convenient, and the operation is simple, convenient, sterile and efficient; the soft capsule can have the functions of uniformly mixing the contents and cleaning under the pushing of the lifting device; the utility model has the advantages of simple and convenient sampling, accurate weighing, multiple functions and improvement of working efficiency and accuracy.
While one embodiment of the present invention has been described in detail, the description is only a preferred embodiment of the present invention and should not be taken as limiting the scope of the utility model. All equivalent changes and modifications made within the scope of the present invention shall fall within the scope of the present invention.

Claims (6)

1. The utility model provides a fixed appearance of taking a sample of medicinal soft capsule which characterized in that: put the thing platform including sample operation panel and sample, the sample is put the thing platform and is located sample operation panel's top, the sample is put and is equipped with elevating gear between thing platform and the sample operation panel, elevating gear is used for driving the sample is put the thing platform and is reciprocated, the sample is put and is equipped with capsule fixing device on the thing platform, capsule fixing device is used for fixing the soft capsule of different shapes.
2. The fixed sampling instrument of medicinal soft capsule of claim 1, characterized in that: capsule fixing device includes that capsule stiff end and capsule move the end, the capsule stiff end is fixed the left side of putting the thing platform in the sample, the capsule moves the end and locates the right side of capsule stiff end, the capsule move the end can for the capsule stiff end removes about, capsule stiff end and capsule move and are equipped with the spring between the end.
3. The fixed sampling instrument of medicinal soft capsule of claim 2, characterized in that: the capsule stiff end includes head rod and first mounting panel, the lower extreme of head rod with the thing platform is connected in the sample, the upper end of head rod with the first mounting panel is connected, the center department of first mounting panel is equipped with aperture adjustable connecting hole.
4. The fixed sampling instrument of medicinal soft capsule of claim 2, characterized in that: the capsule removes the end and includes second connecting rod and second mounting panel, the lower extreme of second connecting rod with the thing platform sliding connection is put in the sample, the upper end of second connecting rod with the second mounting panel is connected, the center department of second mounting panel is equipped with aperture adjustable connecting hole.
5. The fixed sampling instrument of medicinal soft capsule of claim 1, characterized in that: the lifting device comprises two electric hydraulic lifting rods, the fixed ends of the electric hydraulic lifting rods are connected with the sampling operation platform, and the moving ends of the electric hydraulic lifting rods are connected with the sampling object placing platform.
6. The fixed sampling instrument of medicinal soft capsule of claim 1, characterized in that: and a switch assembly for controlling the lifting device to work is arranged on the front side surface of the sampling operation platform.
CN202122862944.8U 2021-11-22 2021-11-22 Fixed sampling instrument for medicinal soft capsules Active CN216349783U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202122862944.8U CN216349783U (en) 2021-11-22 2021-11-22 Fixed sampling instrument for medicinal soft capsules

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202122862944.8U CN216349783U (en) 2021-11-22 2021-11-22 Fixed sampling instrument for medicinal soft capsules

Publications (1)

Publication Number Publication Date
CN216349783U true CN216349783U (en) 2022-04-19

Family

ID=81151422

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202122862944.8U Active CN216349783U (en) 2021-11-22 2021-11-22 Fixed sampling instrument for medicinal soft capsules

Country Status (1)

Country Link
CN (1) CN216349783U (en)

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