CN216333683U

CN216333683U - Helper T cell activation state detection kit

Info

Publication number: CN216333683U
Application number: CN202123096504.2U
Authority: CN
Inventors: 王爱婷; 朱楠楠; 李春雨; 闫奔; 任美佳; 覃婷; 王志媛; 冯丽敏; 张静
Original assignee: Maisaikele Shandong Life Science Co ltd
Current assignee: Maisaikele Shandong Life Science Co ltd
Priority date: 2021-12-10
Filing date: 2021-12-10
Publication date: 2022-04-19
Anticipated expiration: 2031-12-10

Abstract

The utility model discloses an auxiliary T cell activation state detection kit in the technical field of detection kits, which comprises a box body, a partition plate, clamping plates, mounting ports and clamping assemblies, wherein the partition plate is arranged in the box body and is arranged in a rectangular shape, the partition plate is horizontally arranged in the box body, the partition plate is provided with a plurality of mounting ports, the clamping plates are arranged in the mounting ports and are arranged on two sides of each mounting port, the clamping plates in the mounting ports correspond to each other, each clamping plate is connected with the clamping assemblies, each clamping assembly is arranged in the partition plate of the corresponding mounting port, when the auxiliary T cell activation state detection kit is used through a setting device, a container can be directly placed on the partition plate, so that the auxiliary T cell activation state detection kit is more stable, the container is more stable in the device during transportation, and the carrying and transportation are more convenient and rapid through the setting.

Description

Helper T cell activation state detection kit

Technical Field

The utility model relates to the technical field of detection kits, in particular to a kit for detecting the activation state of helper T cells.

Background

T lymphocytes are derived from bone marrow, mature in thymus, are an important member in cellular immunity and play a key role in regulating immunity and immune surveillance. Activating the T cells after antigen stimulation to obtain effector T cells, wherein the effector T cells can secrete cytokines to rapidly eliminate pathogens; however, sustained antigenic stimulation may lead to gradual loss of effector function and proliferative capacity of T cells leading to exhaustion or even apoptosis.

In the prior art, a flow cytometry is generally used for detecting the expression level of a marker in different states to judge the activation state of T cells, and the T cells need to be subpackaged and transported during detection.

SUMMERY OF THE UTILITY MODEL

The present invention aims to provide a kit for detecting the activation state of helper T cells, so as to solve the problems mentioned in the background art.

In order to achieve the purpose, the utility model provides the following technical scheme: the utility model provides an auxiliary T cell activation state detect reagent box, includes box, baffle, splint, installing port and presss from both sides and moves the subassembly, be provided with the baffle in the box, the baffle is the rectangle setting, the baffle level is placed in the box, a plurality of installing ports have been seted up on the baffle, every all be provided with splint in the installing port, splint set up in the both sides of every installing port, every splint in the installing port correspond each other, every splint are all connecting and are pressing from both sides and move the subassembly, every it sets up in the baffle of the installing port that corresponds to press from both sides to move the subassembly.

As a further scheme of the utility model: the clamp moves the subassembly and includes roof, mounting groove, baffle, connecting rod, opening and reset spring, the mounting groove is seted up in the mounting groove that corresponds, reset spring sets up the inner at the mounting groove, the roof is being set up in the mounting groove of reset spring outer end, the splint that correspond are being connected to the connecting rod on the roof, be provided with the baffle on the opening of mounting groove upper end, the baffle blocks the roof.

As a still further scheme of the utility model: the one end of baffle is provided with lifting unit, lifting unit's screw thread mouth sliding connection is at the box internal surface that corresponds one end, the socket has been seted up on the box that the screw thread mouth corresponds, the screw thread mouth sets up in the socket, the other end setting of baffle is in spacing mouthful.

As a still further scheme of the utility model: the lifting assembly comprises a knob, a threaded rod, a threaded hole and a bearing, the bearing is arranged at the bottom end of the socket, the threaded rod is arranged on the bearing and is connected with the threaded hole of the partition plate in a threaded manner, and the knob is arranged at the upper end of the threaded rod.

As a still further scheme of the utility model: the box body is characterized in that a box cover is arranged at the upper end of the box body, the inner part of the box cover is arranged in a hollow mode, the box cover is inserted into the upper end of the box body, and the inner part of the box body is communicated with the inner part of the box cover.

As a still further scheme of the utility model: the box body is characterized in that fixing seats are arranged on the short end faces of two sides of the box body, a connecting plate is arranged on each fixing seat, the connecting plate is hinged to the fixing seats through a rotating rod, a clamping rod is arranged on the inner surface of the lower end of the connecting plate, and a clamping plate is arranged on the box body corresponding to the clamping rod.

Compared with the prior art, the utility model has the beneficial effects that:

1. in the utility model, the container can be placed in the mounting opening through the mounting opening arranged on the partition plate, the mounting opening is internally provided with the mounting groove, a reset spring is arranged in the mounting groove, the top plate is arranged at the front end of the reset spring, the reset spring can push the top plate to move in the mounting groove, a connecting rod is arranged on the top plate and is connected with a clamping plate, when the reset spring pushes the connecting rod, the clamp plate can move along with the connecting rod, a circle of baffle is arranged on the opening at the outer end of the mounting groove, the diameter of the baffle is larger than that of the top plate, the baffle can block the top plate, the top plate can not be dislocated and can not slide out of the mounting groove, after the container is placed between the clamping plates arranged in the mounting port, the clamping plates can block the container, so that the container can be fixed, when the container is transported, the container cannot shake, so that the container is easy to transport and detect and is safer.

2. According to the utility model, one side of the partition plate is connected in the limiting groove, the partition plate can be limited in displacement and can only move up and down on the limiting groove, the threaded opening at the other end of the partition plate is connected with the threaded rod, the knob is arranged at the upper end of the threaded rod and can drive the threaded rod to rotate, the threaded rod can rotate clockwise or anticlockwise, and when the threaded rod rotates anticlockwise, the partition plate can move on the threaded rod, so that the partition plate can move upwards, the container can be driven to the opening of the box body, and the container can be conveniently taken.

Drawings

FIG. 1 is a schematic structural diagram of a kit for detecting the activation state of helper T cells according to the present invention;

FIG. 2 is a sectional view of the whole of a kit for detecting the activation state of helper T cells according to the present invention;

FIG. 3 is an enlarged view of the region A in FIG. 2 of the kit for detecting the activation state of helper T cells according to the present invention.

In the figure: 1. a box body; 2. clamping a plate; 3. a clamping rod; 4. a rotating rod; 5. a connecting plate; 6. a fixed seat; 7. a box cover; 8. a lifting assembly; 801. a knob; 802. a socket; 803. a threaded rod; 804. a threaded opening; 805. a bearing; 9. a limiting port; 10. A partition plate; 11. an installation port; 12. a splint; 13. a clamping assembly; 131. a top plate; 132. mounting grooves; 133. a baffle plate; 134. a connecting rod; 135. a port; 136. a return spring.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

Referring to fig. 1 to 3, in the embodiment of the present invention, an auxiliary T cell activation state detection kit includes a box body 1, a partition plate 10, a clamping plate 12, mounting ports 11, and clamping assemblies 13, the partition plate 10 is disposed in the box body 1, the partition plate 10 is disposed in a rectangular shape, the partition plate 10 is horizontally disposed in the box body 1, the partition plate 10 is provided with a plurality of mounting ports 11, the clamping plate 12 is disposed in each mounting port 11, the clamping plate 12 is disposed on two sides of each mounting port 11, the clamping plates 12 in each mounting port 11 correspond to each other, each clamping plate 12 is connected to the clamping assembly 13, and each clamping assembly 13 is disposed in the partition plate 10 of the corresponding mounting port 11; clamping subassembly 13 includes roof 131, mounting groove 132, baffle 133, connecting rod 134, opening 135 and reset spring 136, mounting groove 132 is seted up in the installing port 11 that corresponds, reset spring 136 sets up the inner at mounting groove 132, roof 131 is being set up in the mounting groove 132 of reset spring 136 outer end, connecting rod 134 on the roof 131 is connecting corresponding splint 12, be provided with baffle 133 on the opening 135 of mounting groove 132 upper end, baffle 133 blocks roof 131, when the device uses, just can directly place the container in the installing port 11 of baffle 10, place the container between splint 12, splint 12 will receive reset spring 136's effect, just can press from both sides the container tight fixedly, thereby make it fixed, just can not take place to rock, thereby it is safer when making its transport.

Wherein, one end of the clapboard 10 is provided with a lifting component 8, a threaded port 804 of the lifting component 8 is connected with the inner surface of the box body 1 at the corresponding end in a sliding way, a socket 802 is arranged on the box body 1 corresponding to the threaded port 804, the threaded port 804 is arranged in the socket 802, and the other end of the clapboard 10 is arranged in the limit port 9; the lifting assembly 8 comprises a knob 801, a threaded rod 803, a threaded port 804 and a bearing 805, the bearing 805 is arranged at the bottom end of the socket 802, the threaded rod 803 is arranged on the bearing 805, the threaded rod 803 is in threaded connection with the threaded port 804 of the partition board 10, the knob 801 is arranged at the upper end of the threaded rod 803, after a container is placed on the partition board 10 through arrangement, the container can be rotated through the threaded rod 803 before and after transportation, the partition board 10 is moved upwards to the opening position of the box body 1, and the container can be placed conveniently.

The upper end of the box body 1 is provided with a box cover 7, the inner part of the box cover 7 is arranged in a hollow way, the box cover 7 is inserted at the upper end of the box body 1, and the inner part of the box body 1 is communicated with the inner part of the box cover 7; be provided with fixing base 6 on the both sides short section terminal surface of box 1, be provided with connecting plate 5 on fixing base 6, connecting plate 5 articulates on fixing base 6 through bull stick 4, card pole 3 has been set up on the lower extreme internal surface of connecting plate 5, be provided with cardboard 2 on the box 1 that card pole 3 corresponds, rotate connecting plate 5 to cardboard 2 positions through setting up, go into the lower extreme of connecting plate 5 with card pole 3 card on the connecting plate 5, just can fix case lid 7, thereby in the protection device of being convenient for.

The working principle of the utility model is as follows: when the device is used, the knob 801 can be rotated, the threaded rod 803 is rotated, the partition plate 10 can be moved on the threaded rod 803 and can be moved on the threaded rod 803, a container can be placed in the mounting opening 11 of the partition plate 10, the container can be placed at the mounting opening 11, the clamping plate 12 can push the container through the reset spring 136, the clamping plate 12 can clamp and fix the container, so that the container is stable, the container cannot shake in the mounting opening 11 during transportation, cells in the container can be protected, and the container is safer during transportation.

The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered to be within the technical scope of the present invention, and equivalent alternatives or modifications according to the technical solution of the present invention and the inventive concept thereof should be covered by the scope of the present invention.

Claims

1. The utility model provides an auxiliary T cell activation state detect reagent box, includes box (1), baffle (10), splint (12), installing port (11) and clamp and move subassembly (13), its characterized in that: be provided with baffle (10) in box (1), baffle (10) are the rectangle setting, baffle (10) level is placed in box (1), a plurality of installing ports (11) have been seted up on baffle (10), every all be provided with splint (12) in installing port (11), splint (12) set up in the both sides of every installing port (11), every splint (12) in installing port (11) correspond each other, every splint (12) are all being connected and are being pressed from both sides and move subassembly (13), every it sets up in baffle (10) of the installing port (11) that correspond to press from both sides and move subassembly (13).

2. The kit for detecting the activation state of helper T cells according to claim 1, wherein: clamping component (13) includes roof (131), mounting groove (132), baffle (133), connecting rod (134), opening (135) and reset spring (136), mounting groove (132) are seted up in corresponding installing port (11), reset spring (136) set up the inner in mounting groove (132), set up roof (131) in mounting groove (132) of reset spring (136) outer end, corresponding splint (12) are being connected in connecting rod (134) on roof (131), be provided with baffle (133) on opening (135) of mounting groove (132) upper end, baffle (133) block roof (131).

3. The kit for detecting the activation state of helper T cells according to claim 1, wherein: one end of the partition board (10) is provided with a lifting component (8), a threaded port (804) of the lifting component (8) is connected to the inner surface of the box body (1) corresponding to one end in a sliding mode, a socket (802) is formed in the box body (1) corresponding to the threaded port (804), the threaded port (804) is arranged in the socket (802), and the other end of the partition board (10) is arranged in a limiting port (9).

4. The kit for detecting the activation state of helper T cells according to claim 3, wherein: the lifting assembly (8) comprises a knob (801), a threaded rod (803), a threaded port (804) and a bearing (805), the bearing (805) is arranged at the bottom end of the socket (802), the threaded rod (803) is arranged on the bearing (805), the threaded rod (803) is in threaded connection with the threaded port (804) of the partition plate (10), and the knob (801) is arranged at the upper end of the threaded rod (803).

5. The kit for detecting the activation state of helper T cells according to claim 1, wherein: the box is characterized in that a box cover (7) is arranged at the upper end of the box body (1), the box cover (7) is arranged in a hollow mode, the box cover (7) is inserted into the upper end of the box body (1), and the interior of the box body (1) is communicated with the interior of the box cover (7).

6. The kit for detecting the activation state of helper T cells according to claim 1, wherein: be provided with on the short section terminal surface of both sides of box (1) fixing base (6), be provided with connecting plate (5) on fixing base (6), connecting plate (5) articulate on fixing base (6) through bull stick (4), set up kelly (3) on the lower extreme internal surface of connecting plate (5), be provided with cardboard (2) on box (1) that kelly (3) correspond.