CN216322145U - Purification equipment of antibody - Google Patents
Purification equipment of antibody Download PDFInfo
- Publication number
- CN216322145U CN216322145U CN202122767263.3U CN202122767263U CN216322145U CN 216322145 U CN216322145 U CN 216322145U CN 202122767263 U CN202122767263 U CN 202122767263U CN 216322145 U CN216322145 U CN 216322145U
- Authority
- CN
- China
- Prior art keywords
- centrifugal
- broken
- purification
- purifying
- shell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Images
Abstract
The utility model discloses antibody purification equipment which comprises a purification shell, a crushing component, a filtering inclined plate, a collecting hopper and a centrifugal component, wherein the purification shell is arranged in a hollow cavity, the crushing component is arranged at the upper end of the purification shell, the filtering inclined plate is arranged in the purification shell and is arranged below the crushing component, the collecting hopper is arranged in the purification shell and is arranged below the filtering inclined plate, the centrifugal component is arranged at the lower end of the purification shell and is arranged below the collecting hopper, the centrifugal component comprises a centrifugal purification box, a centrifugal driven gear, a centrifugal rotating shaft, a centrifugal driving gear, a centrifugal motor and a centrifugal transmission belt, and the centrifugal purification box is symmetrically arranged in two ends of the purification shell. The utility model belongs to the technical field of biotechnology, and particularly provides an antibody purification device which is convenient for crushing cell tissues by a crushing component, is convenient for extracting antibodies in the cell tissues by a centrifugal component, and has the advantages of high practicability, simple operation, reasonable design, good crushing effect and high purification efficiency.
Description
Technical Field
The utility model belongs to the technical field of biotechnology, and particularly relates to antibody purification equipment.
Background
Antibodies are immunoglobulins that bind specifically to antigens, promote phagocytic phagocytosis of viruses by phagocytic cells, and are currently used extensively in the treatment of pathologies. In the process of preparing or using the antibody, separation and purification are needed, and impurities in the mixture are separated so as to improve the purity of the antibody.
The existing antibody separation and purification device has poor crushing effect and is not beneficial to subsequent filtration and purification; the centrifugal efficiency is low, and the operation is complex; and the purified antibody cannot be preserved in time, so that the antibody is easy to lose activity. Therefore, a new antibody purification apparatus is urgently needed to solve the above problems.
SUMMERY OF THE UTILITY MODEL
In order to solve the existing problems, the utility model provides the antibody purification equipment which is convenient for the crushing of the cell tissue by the crushing component, convenient for the extraction of the antibody in the cell tissue by the centrifugal component, high in practicability, simple in operation, reasonable in design, good in crushing effect and high in purification efficiency.
The technical scheme adopted by the utility model is as follows: the utility model relates to a purifying device of an antibody, which comprises a purifying shell, a crushing component, a filtering inclined plate, a collecting hopper and a centrifugal component, wherein the purifying shell is arranged in a hollow cavity, the crushing component is arranged at the upper end of the purifying shell, the filtering inclined plate is arranged in the purifying shell and is arranged below the crushing component, the collecting hopper is arranged in the purifying shell and is arranged below the filtering inclined plate, the centrifugal component is arranged at the lower end of the purifying shell and is arranged below the collecting hopper, the centrifugal component comprises a centrifugal purifying box, a centrifugal driven gear, a centrifugal rotating shaft, a centrifugal driving gear, a centrifugal motor and a centrifugal driving belt, the centrifugal purifying box is symmetrically arranged in two ends of the purifying shell, the centrifugal purifying box is arranged in a hollow cavity with an opening at the upper end, the centrifugal driven gear is arranged below the center of the centrifugal purifying box, the centrifugal rotating shaft is arranged below the centrifugal purifying box and is rotatably arranged between the centrifugal driven gears, centrifugal pivot both ends are located to centrifugal driving gear symmetry and centrifugal driven gear one side is located in the rotation, centrifugal driving gear and centrifugal driven gear meshing, purification casing diapire top is located and centrifugal pivot below is located in the rotation of centrifugal motor, centrifugal drive belt is around locating centrifugal motor output, centrifugal pivot center department lateral wall, and centrifugal motor passes through centrifugal drive belt and drives centrifugal pivot rotation, and the centrifugal driving gear at centrifugal pivot both ends drives centrifugal driven gear and rotates, and centrifugal driven gear drives centrifugal purification box and rotates, and the cell tissue in the centrifugal purification box of the centrifugal processing of being convenient for draws liquid.
Further, broken subassembly includes broken filter, broken stripper plate, broken hydraulic stem, broken upper teeth and broken lower teeth, the upper end in the purification casing is located to broken filter, the broken stripper plate slides and locates in the purification casing and locate broken filter top, broken stripper plate center department top is located to broken hydraulic stem, the one end that broken stripper plate was kept away from to broken hydraulic stem link up purification casing roof, broken stripper plate diapire is located to the broken upper teeth, broken filter roof is located to broken lower teeth, and broken hydraulic stem extension drives broken stripper plate and is close to broken filter, and tooth and the broken lower teeth of broken filter roof are smashed cell tissue in the breakage of broken stripper plate diapire.
Furthermore, a feeding hopper is arranged on one side of the upper end of the purification shell, the lower end of the feeding hopper is connected with the purification shell, the feeding hopper is arranged above the crushing and filtering plate, and cell tissues can be conveniently fed into the purification shell through the feeding hopper.
Furthermore, broken guide bars are symmetrically arranged at two ends above the broken extrusion plate, one end, far away from the broken extrusion plate, of each broken guide bar penetrates through the top wall of the purification shell, and the broken guide bars are convenient to strengthen the moving stability of the broken extrusion plate.
Further, it is equipped with the discharging pipe to collect hopper below, discharging pipe one end is connected with collection hopper diapire, the discharging pipe lateral wall is equipped with the bleeder valve, and the bleeder valve is convenient for control and is collected the cell tissue extract in the hopper and flow out from the discharging pipe.
Further, it is the slope form setting that one end is high one end is low to filter the swash plate, the one end that filters the swash plate low is equipped with the scum pipe, scum pipe one end is connected with purification casing lateral wall, scum pipe lateral wall is equipped with the slag discharge valve, and the cell tissue that the scum valve was convenient for on the control filter the swash plate is discharged from the scum pipe.
Furthermore, purification casing lower extreme lateral wall is equipped with the refrigerator, the refrigerator is located centrifugal purification box one side, and the refrigerator is convenient for prevent that the antibody after the purification from losing activity.
Furthermore, the purification casing lateral wall is articulated to be equipped with the antibody and to take the door, the antibody is taken the door and is located centrifugation purification box one side, and the antibody is taken the door and is convenient for take the purification antibody in the centrifugation purification box.
The utility model with the structure has the following beneficial effects: the purification equipment of antibody that this scheme provided, broken hydraulic stem extension drive broken stripper plate is close to broken filter and smashes cell tissue, and centrifugal motor passes through centrifugal drive belt and drives centrifugal pivot rotation, and the centrifugation driving gear at centrifugation pivot both ends drives centrifugation purification box through centrifugation driven gear and rotates, and the cell tissue in the centrifugation of being convenient for purification box draws liquid, and the practicality is high, easy operation, reasonable in design, crushing effect is good, purification efficiency is high.
Drawings
FIG. 1 is a front view of an antibody purification apparatus according to the present embodiment;
FIG. 2 is a schematic diagram of the structure of the antibody purification apparatus proposed in the present embodiment.
The accompanying drawings, which are included to provide a further understanding of the utility model and are incorporated in and constitute a part of this specification, illustrate embodiments of the utility model and together with the description serve to explain the principles of the utility model and not to limit the utility model. In the drawings: 1. purification casing, 2, crushing subassembly, 3, filtration swash plate, 4, collection hopper, 5, centrifugal subassembly, 6, centrifugation purification box, 7, centrifugation driven gear, 8, centrifugation pivot, 9, centrifugation driving gear, 10, centrifugal motor, 11, centrifugal drive belt, 12, broken filter, 13, broken stripper plate, 14, broken hydraulic stem, 15, broken upper teeth, 16, broken lower teeth, 17, go into the hopper, 18, broken guide bar, 19, discharging pipe, 20, bleeder valve, 21, slag discharge pipe, 22, slag discharge valve, 23, refrigerator, 24, antibody take-up door.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments; all other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
As shown in fig. 1 and fig. 2, the antibody purification apparatus provided by the present scheme comprises a purification housing 1, a crushing assembly 2, a filtration inclined plate 3, a collection hopper 4 and a centrifugal assembly 5, wherein the purification housing 1 is a hollow cavity, the crushing assembly 2 is arranged at the upper end of the purification housing 1, the filtration inclined plate 3 is arranged in the purification housing 1 and below the crushing assembly 2, the collection hopper 4 is arranged in the purification housing 1 and below the filtration inclined plate 3, the centrifugal assembly 5 is arranged at the lower end of the purification housing 1 and below the collection hopper 4, the centrifugal assembly 5 comprises a centrifugal purification box 6, a centrifugal driven gear 7, a centrifugal rotating shaft 8, a centrifugal driving gear 9, a centrifugal motor 10 and a centrifugal transmission belt 11, the centrifugal purification box 6 is symmetrically arranged at two ends of the purification housing 1, the centrifugal purification box 6 is a hollow cavity with an open upper end, centrifugal driven gear 7 locates the below of 6 center departments of centrifugal purification box, centrifugal pivot 8 is located the below of centrifugal purification box 6 and is rotated and locate between centrifugal driven gear 7, 8 both ends of centrifugal pivot are located to centrifugal driving gear 9 symmetry and are rotated and locate 7 one sides of centrifugal driven gear, centrifugal driving gear 9 and the meshing of centrifugal driven gear 7, 1 diapire top of purification casing and locate centrifugal pivot 8 below are located in the rotation of centrifugal motor 10, centrifugal drive belt 11 is around locating centrifugal motor 10 output, the 8 center departments lateral wall of centrifugal pivot.
Wherein, the crushing component 2 comprises a crushing filter plate 12, a crushing extrusion plate 13, a crushing hydraulic rod 14, a crushing upper tooth 15 and a crushing lower tooth 16, the crushing filter plate 12 is arranged at the inner upper end of the purification shell 1, the crushing extrusion plate 13 is slidably arranged in the purification shell 1 and is arranged above the crushing filter plate 12, the crushing hydraulic rod 14 is arranged above the center of the crushing extrusion plate 13, one end of the crushing hydraulic rod 14 far away from the crushing extrusion plate 13 is communicated with the top wall of the purification shell 1, the crushing upper tooth 15 is arranged at the bottom wall of the crushing extrusion plate 13, the crushing lower tooth 16 is arranged at the top wall of the crushing filter plate 12, one side of the upper end of the purification shell 1 is provided with a feeding hopper 17, the lower end of the feeding hopper 17 is connected with the purification shell 1, the feeding hopper 17 is arranged above the crushing filter plate 12, two ends above the crushing extrusion plate 13 are symmetrically provided with crushing guide rods 18, one end of the crushing guide rods 18 far away from the crushing extrusion plate 13 is communicated with the top wall of the purification shell 1, collect 4 below of hopper and be equipped with discharging pipe 19, 19 one end of discharging pipe is connected with 4 diapire of collection hopper, 19 lateral walls of discharging pipe are equipped with bleeder valve 20, it is the slope form setting that the high one end of one end is low to filter swash plate 3, the one end that filters the swash plate 3 low is equipped with scum pipe 21, scum pipe 21 one end is connected with 1 lateral wall of purification casing, scum pipe 21 lateral wall is equipped with scum valve 22, 1 lower extreme lateral wall of purification casing is equipped with refrigerator 23, centrifugal purification box 6 one side is located to refrigerator 23, 1 lateral wall of purification casing is articulated to be equipped with the antibody door 24 of taking, the antibody door 24 of taking is located centrifugal purification box 6 one side.
When the cell tissue purification device is used specifically, cell tissue is put into a purification shell 1 through a feeding hopper 17 and falls on a crushing filter plate 12, a crushing hydraulic rod 14 extends to drive a crushing extrusion plate 13 to approach the crushing filter plate 12, crushing upper teeth 15 on the bottom wall of the crushing extrusion plate 13 and crushing lower teeth 16 on the top wall of the crushing filter plate 12 crush the cell tissue, the crushed cell tissue falls on a filtering inclined plate 3 along the crushing filter plate 12, cell tissue extracting solution falls into a collecting hopper 4 along the filtering inclined plate 3, cell tissue crushing slag is accumulated at one end of a slag discharge pipe 21 along the filtering inclined plate 3, a discharge valve 20 is opened, the cell tissue extracting solution in the collecting hopper 4 flows into a centrifugal purification box 6 from a discharge pipe 19, a centrifugal motor 10 is started, the centrifugal motor 10 drives a centrifugal rotating shaft 8 to rotate through a centrifugal transmission belt 11, centrifugal driving gears 9 at two ends of the centrifugal rotating shaft 8 drive a centrifugal driven gear 7 to rotate, centrifugation driven gear 7 drives centrifugation purification box 6 and rotates, the cell tissue of being convenient for centrifugation in the purification box 6 draws liquid, refrigerator 23 is convenient for guarantee to be in low temperature environment in the centrifugation purification box 6, prevent that the antibody after the purification from losing activity, after the purification, open scum valve 22, make the cell tissue disintegrating slag on the filtration swash plate 3 discharge from scum pipe 21, when the antibody after the purification of taking, open the antibody door of taking 24, from the centrifugation purification box 6 in the purification antibody can, the practicality is high, and the operation is simple, and reasonable design, crushing effect is good, purification efficiency is high.
It is noted that, herein, relational terms such as first and second, and the like may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the utility model, the scope of which is defined in the appended claims and their equivalents.
Claims (8)
1. An apparatus for purifying an antibody, comprising: comprises a purifying shell, a crushing component, a filtering inclined plate, a collecting hopper and a centrifugal component, wherein the purifying shell is arranged in a hollow cavity, the crushing component is arranged at the upper end of the purifying shell, the filtering inclined plate is arranged in the purifying shell and below the crushing component, the collecting hopper is arranged in the purifying shell and below the filtering inclined plate, the centrifugal component is arranged at the lower end of the purifying shell and below the collecting hopper, the centrifugal component comprises a centrifugal purifying box, a centrifugal driven gear, a centrifugal rotating shaft, a centrifugal driving gear, a centrifugal motor and a centrifugal driving belt, the centrifugal purifying box is symmetrically arranged in two ends of the purifying shell, the centrifugal purifying box is arranged in a hollow cavity with an opening at the upper end, the centrifugal driven gear is arranged below the center of the centrifugal purifying box, the centrifugal rotating shaft is arranged below the centrifugal purifying box and rotatably arranged between the centrifugal driven gears, the centrifugal driving gear is symmetrically arranged at two ends of the centrifugal rotating shaft and is rotatably arranged on one side of the centrifugal driven gear, the centrifugal driving gear is meshed with the centrifugal driven gear, the centrifugal motor is rotatably arranged above the bottom wall of the purification shell and below the centrifugal rotating shaft, and the centrifugal driving belt is wound on the side wall of the center of the centrifugal motor and the output end of the centrifugal rotating shaft.
2. The apparatus for purifying an antibody according to claim 1, wherein: broken subassembly includes broken filter, broken stripper plate, broken hydraulic stem, broken upper teeth and broken lower teeth, the upper end in the purification casing is located to broken filter, the broken stripper plate slides and locates in the purification casing and locate broken filter top, broken stripper plate center department top is located to broken hydraulic stem, the one end that broken stripper plate was kept away from to broken hydraulic stem link up purification casing roof, broken stripper plate diapire is located to broken upper teeth, broken filter roof is located to broken lower teeth.
3. The apparatus for purifying an antibody according to claim 1, wherein: the purification shell is characterized in that a feeding hopper is arranged on one side of the upper end of the purification shell, the lower end of the feeding hopper is connected with the purification shell, and the feeding hopper is arranged above the crushing and filtering plate.
4. The apparatus for purifying antibody according to claim 2, wherein: broken guide bars are symmetrically arranged at two ends above the broken extrusion plate, and one end, far away from the broken extrusion plate, of each broken guide bar penetrates through the top wall of the purification shell.
5. The apparatus for purifying an antibody according to claim 1, wherein: the collecting hopper is provided with a discharging pipe below, one end of the discharging pipe is connected with the bottom wall of the collecting hopper, and the side wall of the discharging pipe is provided with a discharging valve.
6. The apparatus for purifying an antibody according to claim 1, wherein: the filter sloping plate is the slope form setting that one end is high and the other end is low, the one end that the filter sloping plate is low is equipped with the scum pipe, scum pipe one end is connected with purification casing lateral wall, the scum pipe lateral wall is equipped with the scum valve.
7. The apparatus for purifying an antibody according to claim 1, wherein: the side wall of the lower end of the purification shell is provided with a refrigerator, and the refrigerator is arranged on one side of the centrifugal purification box.
8. The apparatus for purifying an antibody according to claim 1, wherein: the side wall of the purification shell is hinged with an antibody taking door, and the antibody taking door is arranged on one side of the centrifugal purification box.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202122767263.3U CN216322145U (en) | 2021-11-12 | 2021-11-12 | Purification equipment of antibody |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202122767263.3U CN216322145U (en) | 2021-11-12 | 2021-11-12 | Purification equipment of antibody |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN216322145U true CN216322145U (en) | 2022-04-19 |
Family
ID=81146969
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202122767263.3U Active CN216322145U (en) | 2021-11-12 | 2021-11-12 | Purification equipment of antibody |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN216322145U (en) |
-
2021
- 2021-11-12 CN CN202122767263.3U patent/CN216322145U/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN110496439B (en) | Prevent sewage treatment plant of jam | |
| CN108970783A (en) | A kind of efficient fixed-end forces device | |
| CN111790189A (en) | Environment-friendly kitchen waste resource recycling and residue-liquid separating device | |
| CN113304541A (en) | Cosmetic extracting solution processing device with residue filtering function | |
| CN216322145U (en) | Purification equipment of antibody | |
| CN214457345U (en) | Anti-clogging sewage treatment device convenient for purifying domestic wastewater | |
| CN219309649U (en) | Solid-liquid separation device for garbage disposal | |
| CN214597340U (en) | Chinese patent medicine filtering and extracting tank | |
| CN211585308U (en) | Purification device of herbaceous plant | |
| CN212440267U (en) | Sewage treatment debris separator | |
| CN113082793A (en) | Waste water purification scrubbing device with automatic reagent feeding | |
| CN218357669U (en) | Filter equipment is used in chinese bee honey processing | |
| CN209348763U (en) | Grinding device is used in a kind of production of vegetables and fruits ferment | |
| CN111940027A (en) | Waste cloth cutting and collecting device based on Internet of things big data technology | |
| CN214599300U (en) | Lutein draws uses filter equipment | |
| CN220364410U (en) | Wastewater treatment device | |
| CN216571790U (en) | Domestic sewage treatment tank | |
| CN217492106U (en) | Solid useless breaker for processing convenient to dismantle | |
| CN215559764U (en) | Avoid extraction pipeline for sludge extraction of jam | |
| CN219723154U (en) | Crushing device for garlic processing | |
| CN218308345U (en) | Straw material reducing mechanism is used in environmental protection tableware preparation | |
| CN219502839U (en) | Integrated garbage clearing and treating device | |
| CN216779016U (en) | Roxburgh rose dreg processing device for production of roxburgh rose juice | |
| CN218437393U (en) | Ponding collection device for town road | |
| CN219651908U (en) | Novel garbage classification facility |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant |